EyePub Date : 2025-02-17DOI: 10.1038/s41433-025-03686-5
Yanping Zhou, Wenchang Jia, Jianling Song, Min Li, Wei Dai, Jian Zou, Jing Zhou, Xiangwu Chen, Xiaopan Li
{"title":"Burdens and trends of age-related macular degeneration at global, regional, and national levels,1990-2021: findings from the 2021 global burden of disease study.","authors":"Yanping Zhou, Wenchang Jia, Jianling Song, Min Li, Wei Dai, Jian Zou, Jing Zhou, Xiangwu Chen, Xiaopan Li","doi":"10.1038/s41433-025-03686-5","DOIUrl":"https://doi.org/10.1038/s41433-025-03686-5","url":null,"abstract":"<p><strong>Objectives: </strong>To assess global, regional, and national burdens and trends of age-related macular degeneration (AMD) from 1990 to 2021.</p><p><strong>Methods: </strong>Data from the Global Burden of disease Study 2021(GBD 2021) were used. The primary measurement were prevalent cases, years lived with disability (YLDs), age-standardised prevalence rate (ASPR) and age-standardised YLDs rate (ASYR), categorized by age and sociodemographic index (SDI). Trend analysis was measured by calculating average annual percentage change (AAPC) of ASPR and ASYR.</p><p><strong>Results: </strong>Globally, the prevalent AMD cases increased to 8,057,520.459 (95% uncertainty interval [UI], 6,705,283.83 to 9,823,237.34) in 2021, with associated YLDs rising to 577,984.5004 (95% UI, 401,188.20 to 797,657.63). AMD burdens varied across regions and countries, as well as level of SDI development. China, India, and the United States of America (USA) were the top three countries with AMD cases. Caribbean regions have significant lower ASPR and ASYR of AMD. The AMD burden peaked between ages 65-69. Females had a significantly higher burden of AMD compared to males. From 1990 to 2021, the global ASPR and ASYR showed downward trend (AAPC = -0.15, 95% confidence interval [CI], -0.19 to -0.12, P < 0.001; AAPC = -0.69, 95% CI, -0.71 to -0.67, P < 0.001) respectively. The USA is the only developed country showed decreasing AAPCs of ASPR and ASYR from 1990 to 2021 but increasing AAPCs of ASPR and ASYR from 2012 to 2021.</p><p><strong>Conclusions: </strong>AMD burdens increased over 30 years, varying by age, sex, and SDI, guiding global strategies and public health interventions.</p>","PeriodicalId":12125,"journal":{"name":"Eye","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143440269","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
EyePub Date : 2025-02-15DOI: 10.1038/s41433-025-03690-9
Natasha Mayer, Julie Cassidy, Lauren M Wasser, Peggy J Liu, Andrew M Williams
{"title":"Seeing the unseen: uncovering health-related social needs through universal screening at an academic ophthalmology practice.","authors":"Natasha Mayer, Julie Cassidy, Lauren M Wasser, Peggy J Liu, Andrew M Williams","doi":"10.1038/s41433-025-03690-9","DOIUrl":"https://doi.org/10.1038/s41433-025-03690-9","url":null,"abstract":"<p><strong>Background: </strong>Health-related social needs (HRSN), or unmet conditions that are important to maintain health (such as finances and transportation), contribute to vision health disparities. The purpose of this study is to identify the unmet HRSN of ophthalmology clinic patients.</p><p><strong>Methods: </strong>This retrospective, cross-sectional study examined HRSN survey results from adult patients who checked in for a clinic visit at a tertiary academic eye centre from April 28, 2022, to March 31, 2023. Demographics and visual acuity were extracted from the electronic health record, and their reported HRSNs were evaluated using binary logistic regression.</p><p><strong>Results: </strong>Of 1413 patients who completed the survey, 194 (13.7%) screened positive for at least one HRSN. The most frequently reported need was food insecurity (99/1303, 7.6%), followed by transportation (68/1340, 5.1%), housing instability (63/1305, 4.8%), financial insecurity (46/1293, 3.6%), and homelessness (10/1330, 0.8%). Patients with at least one reported HRSN were more likely to be Black compared to White (OR 4.03, 95% CI: 2.71-5.96), female compared to male (OR 1.88, 95% CI: 1.34-2.62), and younger than 65 years of age compared to 65 to 75 years (OR 2.35, 95% CI: 1.68-3.37) or older than 75 years (OR 4.62, 95% CI: 2.54-8.16). Presence of at least one HRSN was associated with visual impairment, with greater odds of best-corrected visual acuity worse than 20/40 in the group with HRSN compared to without HRSN (OR 1.55, 95% CI: 1.09-2.19).</p><p><strong>Conclusion: </strong>Integrating a screening questionnaire in ophthalmology clinics can uncover unaddressed HRSN, enabling resource allocation to mitigate vision health disparities.</p>","PeriodicalId":12125,"journal":{"name":"Eye","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143425310","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
EyePub Date : 2025-02-15DOI: 10.1038/s41433-025-03704-6
Fikret Ucar, Muhammed Sağdıç
{"title":"Effects of enhanced monofocal intraocular lenses on intermediate and near vision.","authors":"Fikret Ucar, Muhammed Sağdıç","doi":"10.1038/s41433-025-03704-6","DOIUrl":"https://doi.org/10.1038/s41433-025-03704-6","url":null,"abstract":"","PeriodicalId":12125,"journal":{"name":"Eye","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143425308","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
EyePub Date : 2025-02-15DOI: 10.1038/s41433-025-03674-9
Raquel Quintanilla, Luke van Leeuwen, Arjun Sharma, Ta Chen Chang, Elizabeth Hodapp, John McSoley, Alana Grajewski, Elena Bitrian
{"title":"Prescribing carbonic anhydrase inhibitors to patients with \"sulfa\" antibiotics allergy: do we dare?","authors":"Raquel Quintanilla, Luke van Leeuwen, Arjun Sharma, Ta Chen Chang, Elizabeth Hodapp, John McSoley, Alana Grajewski, Elena Bitrian","doi":"10.1038/s41433-025-03674-9","DOIUrl":"https://doi.org/10.1038/s41433-025-03674-9","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate if provider characteristics affect attitude toward carbonic anhydrase inhibitors (CAI) prescription for patients with history of sulfonamide antibiotic (SA) hypersensitivity.</p><p><strong>Methods: </strong>A survey querying providers' attitudes toward CAI prescription in hypothetical patients with prior SA hypersensitivity was distributed to four ophthalmology and optometry organizations. Logistic regression was used to assess the relationship between avoiding CAI and profession, specialty, organizational affiliation, and years in practice.</p><p><strong>Results: </strong>Of 250 respondents, 27% and 52% would avoid topical and oral CAI, respectively, in patients with prior SA rash and/or urticaria. >90% would avoid oral CAI in patients with prior severe SA hypersensitivity. Respondents with >10 years in practice were more likely to avoid oral CAI in patients with prior SA rash and/or urticaria than those with ≤10 (OR 2.27, p = 0.002). Respondents affiliated with non-glaucoma organizations were more likely to avoid oral CAI in patients with prior SA rash and/or urticaria than those affiliated with glaucoma organizations (p = 0.03). Providers without glaucoma training were more likely to avoid topical CAI in patients with prior SA rash and/or urticaria (p = 0.004) and anaphylaxis (p = 0.01) than glaucoma-trained providers.</p><p><strong>Conclusions: </strong>Despite no supporting evidence, a significant number of respondents would avoid CAI in patients with prior SA hypersensitivity. Respondents without glaucoma training, no affiliation with a glaucoma organization, and >10 years in practice are more likely to avoid CAI in patients with type I SA hypersensitivity. Providers should be informed of the low cross-reactivity risk between CAI and SA so more patients may benefit from these drugs.</p>","PeriodicalId":12125,"journal":{"name":"Eye","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143425262","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
EyePub Date : 2025-02-15DOI: 10.1038/s41433-025-03708-2
Shuyi Zhang, Truong X. Nguyen, Xujia Liu, Simon K. H. Szeto, Carol Y. Cheung, An Ran Ran
{"title":"Moving artificial intelligence development to deployment in ophthalmology: randomised controlled trials are warranted","authors":"Shuyi Zhang, Truong X. Nguyen, Xujia Liu, Simon K. H. Szeto, Carol Y. Cheung, An Ran Ran","doi":"10.1038/s41433-025-03708-2","DOIUrl":"10.1038/s41433-025-03708-2","url":null,"abstract":"","PeriodicalId":12125,"journal":{"name":"Eye","volume":"39 5","pages":"816-818"},"PeriodicalIF":2.8,"publicationDate":"2025-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143425236","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
EyePub Date : 2025-02-14DOI: 10.1038/s41433-025-03677-6
Maria S. Varughese, Sarita Jacob
{"title":"Diabetic retinopathy and pregnancy: an overview of the predictive risk factors for progressive worsening of eye disease during the antenatal period","authors":"Maria S. Varughese, Sarita Jacob","doi":"10.1038/s41433-025-03677-6","DOIUrl":"10.1038/s41433-025-03677-6","url":null,"abstract":"","PeriodicalId":12125,"journal":{"name":"Eye","volume":"39 5","pages":"812-813"},"PeriodicalIF":2.8,"publicationDate":"2025-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.nature.com/articles/s41433-025-03677-6.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143425306","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
EyePub Date : 2025-02-14DOI: 10.1038/s41433-025-03699-0
David J Ramsey, Alexander Huther, Ruba E Muhtaseb
{"title":"Response to 'Comment on: 'Optimizing open-angle glaucoma risk assessment in patients with retinal vein occlusions\".","authors":"David J Ramsey, Alexander Huther, Ruba E Muhtaseb","doi":"10.1038/s41433-025-03699-0","DOIUrl":"https://doi.org/10.1038/s41433-025-03699-0","url":null,"abstract":"","PeriodicalId":12125,"journal":{"name":"Eye","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143425278","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
EyePub Date : 2025-02-14DOI: 10.1038/s41433-025-03684-7
Seyed-Hashem Daryabari, Seyyed Morteza Hosseini Imeni, Seyyed Rahim Hassanpour
{"title":"Ophthalmologic trauma following the pager explosion in Lebanon","authors":"Seyed-Hashem Daryabari, Seyyed Morteza Hosseini Imeni, Seyyed Rahim Hassanpour","doi":"10.1038/s41433-025-03684-7","DOIUrl":"10.1038/s41433-025-03684-7","url":null,"abstract":"","PeriodicalId":12125,"journal":{"name":"Eye","volume":"39 5","pages":"814-815"},"PeriodicalIF":2.8,"publicationDate":"2025-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143425242","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
EyePub Date : 2025-02-13DOI: 10.1038/s41433-025-03656-x
Eleanor McCance, Ingeborg Steinbach, Daniel S Morris
{"title":"Comparative carbon footprinting study of reusable vs. disposable instruments in cataract surgery.","authors":"Eleanor McCance, Ingeborg Steinbach, Daniel S Morris","doi":"10.1038/s41433-025-03656-x","DOIUrl":"https://doi.org/10.1038/s41433-025-03656-x","url":null,"abstract":"<p><strong>Background: </strong>Theatre activity is a major source of hospital waste, accounting for 21-30% of total output, and is 3-6 times more energy-intensive than any other hospital department. Cataract remains the leading cause of blindness worldwide, and cataract surgery is the most commonly performed surgical procedure worldwide, but to date has received little analysis in this field. The aim of this study was to evaluate the carbon impact of streamlining single-use packs, and transitioning from single-use items, to reusable equivalents in cataract surgery.</p><p><strong>Methods: </strong>A focus group and prospective audit was carried out to identify single-use pack items for streamlining. A bottom-up, process-based carbon footprint analysis was conducted of single-use items and reusable alternatives using activity data provided by the suppliers and greenhouse gas (GHG) conversion factors from the UK Government GHG Conversion Factors for Company Reporting database.</p><p><strong>Results: </strong>Total carbon savings from streamlining was 935 kgCO2e/year, and switching, was 309 kgCO2e/year. Single-use items had a 27 times greater carbon footprint than reusable equivalents (322 kgCO2 vs. 12 kgCO2e respectively). A net carbon saving was achieved from 19 or more re-uses of the reusable items compared to single-use equivalents.</p><p><strong>Conclusions: </strong>This study provides evidence of carbon emissions savings both from streamlining disposable instruments in cataract surgical packs, and from switching from single-use to reusable instruments. Mitigation strategies targeting hotspots in resource intensive areas will be an important aspect of reducing the climate burden of surgery. Change in practice and policy is required in all surgical specialities to realize net zero carbon healthcare.</p>","PeriodicalId":12125,"journal":{"name":"Eye","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143413896","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}