Expert Review of Respiratory Medicine最新文献_第10页

Selection of the access channel in bronchoscopic intervention 支气管镜介入治疗通道的选择

IF 3.9 3区医学

Expert Review of Respiratory Medicine Pub Date : 2022-06-03 DOI: 10.1080/17476348.2022.2089656

Hui Chen, Yang Yao, Sheng-yu Wang, Song Liu, Lin Yang

{"title":"Selection of the access channel in bronchoscopic intervention","authors":"Hui Chen, Yang Yao, Sheng-yu Wang, Song Liu, Lin Yang","doi":"10.1080/17476348.2022.2089656","DOIUrl":"https://doi.org/10.1080/17476348.2022.2089656","url":null,"abstract":"ABSTRACT Background At present, bronchoscopic intervention has become an important treatment approach for central airway obstruction (CAO). Choosing an appropriate access channel for different patients during this operation has become a research focus. Methods Data of bronchoscopic interventions in 201 patients with CAO in which one of endotracheal intubation, laryngeal mask, or rigid bronchoscope were used as the only access channel were retrospectively reviewed. Results The total immediate effective rate was 94.1% (398/423), and the main complications related to the access channels included hypoxemia, elevated arterial partial pressure of carbon dioxide, arrhythmia, airway mucosa tear, glottic edema, vocal cord injury, tooth loss, massive bleeding, airway mucosal necrosis, and asphyxia. The incidence of complications was 16.8% (71/423). Glottic edema was the most common complication with an incidence of 7.8% (33/423) and accounted for 46.5% of all complications. Glottic edema only occurred in the laryngeal mask and rigid bronchoscope groups, and the incidence was significantly correlated with the operation time (p < 0.001). Massive bleeding related to the access channel remains the most serious complication. Conclusions Endotracheal intubation, laryngeal mask, and rigid bronchoscope each have their own advantages and disadvantages. The most appropriate access channel should depend on a comprehensive assessment of the patient.","PeriodicalId":12103,"journal":{"name":"Expert Review of Respiratory Medicine","volume":"16 1","pages":"707 - 712"},"PeriodicalIF":3.9,"publicationDate":"2022-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47478129","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Urine biomarkers of pulmonary tuberculosis 肺结核的尿液生物标志物

IF 3.9 3区医学

Expert Review of Respiratory Medicine Pub Date : 2022-06-03 DOI: 10.1080/17476348.2022.2090341

E. Khimova, X. Gonzalo, Popova Yulia, P. Eliseev, A. Mariandyshev, V. Nikolayevskyy, A. Broda, F. Drobniewski

{"title":"Urine biomarkers of pulmonary tuberculosis","authors":"E. Khimova, X. Gonzalo, Popova Yulia, P. Eliseev, A. Mariandyshev, V. Nikolayevskyy, A. Broda, F. Drobniewski","doi":"10.1080/17476348.2022.2090341","DOIUrl":"https://doi.org/10.1080/17476348.2022.2090341","url":null,"abstract":"ABSTRACT Introduction Sputum-based tuberculosis diagnosis does not address the needs of certain categories of patients. Active development of a noninvasive urine-based diagnosis could provide an alternative approach. We reviewed publications covering more than 30 urine biomarkers proposed as significant for TB diagnosis. Analytical approaches were heterogeneous in design and methods; few studies on diagnostic outcome prediction described a formal specificity and sensitivity analysis. Areas covered This review describes studies of non-sputum diagnostic approaches of pulmonary TB based on urine using specific TB biomarkers. The search was performed until December 2021, using terms [Tuberculosis] + [urine] + [biomarkers] in PubMed and Cochrane databases. Publications concerning LAM urine diagnostics were excluded as they have been described elsewhere. Expert opinion Microbiological culture of sputum is considered to be the ‘gold standard’ diagnostic for pulmonary TB but the methodology is slow due to the slow growth of the TB bacteria. Urine provides a large volume of sample. Investigators have evaluated urine for either TB pathogen biomarkers or host biomarkers with some success as the review demonstrates. Detection sensitivity remains a significant problem. In future, combination of host and pathogen biomarkers could increase the sensitivity and specificity of TB diagnosis.","PeriodicalId":12103,"journal":{"name":"Expert Review of Respiratory Medicine","volume":"16 1","pages":"615 - 621"},"PeriodicalIF":3.9,"publicationDate":"2022-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46412645","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Vaccination and modern management of chronic obstructive pulmonary disease – a narrative review 慢性阻塞性肺病的疫苗接种和现代管理——叙述性综述

IF 3.9 3区医学

Expert Review of Respiratory Medicine Pub Date : 2022-06-03 DOI: 10.1080/17476348.2022.2092099

Oana Joean, T. Welte

{"title":"Vaccination and modern management of chronic obstructive pulmonary disease – a narrative review","authors":"Oana Joean, T. Welte","doi":"10.1080/17476348.2022.2092099","DOIUrl":"https://doi.org/10.1080/17476348.2022.2092099","url":null,"abstract":"ABSTRACT Introduction Chronic obstructive pulmonary disease (COPD) carries a tremendous societal and individual burden, posing significant challenges for public health systems worldwide due to its high morbidity and mortality. Due to aging and multimorbidity but also in the wake of important progress in deciphering the heterogeneous disease endotypes, an individualized approach to the prevention and management of COPD is necessary. Areas covered This article tackles relevant immunization strategies that are available or still under development with a focus on the latest evidence but also controversies around different regional immunization approaches. Further, we present the crossover between chronic lung inflammation and lung microbiome disturbance as well as its role in delineating COPD endotypes. Moreover, the article attempts to underline endotype-specific treatment approaches. Lastly, we highlight non-pharmacologic prevention and management programs in view of the challenges and opportunities of the COVID-19 era. Expert opinion Despite the remaining challenges, personalized medicine has the potential to offer tailored approaches to prevention and therapy and promises to improve the care of patients living with COPD.","PeriodicalId":12103,"journal":{"name":"Expert Review of Respiratory Medicine","volume":"16 1","pages":"605 - 614"},"PeriodicalIF":3.9,"publicationDate":"2022-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47242018","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Bronchiectasis in patients with antineutrophil cytoplasmic antibody-associated vasculitis: a case control study on clinical features and prognosis 抗中性粒细胞胞浆抗体相关性血管炎患者支气管扩张症的临床特征和预后的病例对照研究

IF 3.9 3区医学

Expert Review of Respiratory Medicine Pub Date : 2022-06-03 DOI: 10.1080/17476348.2022.2088512

Jiaqi Ren, Yanling Ding, Jinxia Zhao, Yongchang Sun

{"title":"Bronchiectasis in patients with antineutrophil cytoplasmic antibody-associated vasculitis: a case control study on clinical features and prognosis","authors":"Jiaqi Ren, Yanling Ding, Jinxia Zhao, Yongchang Sun","doi":"10.1080/17476348.2022.2088512","DOIUrl":"https://doi.org/10.1080/17476348.2022.2088512","url":null,"abstract":"ABSTRACT Background Bronchiectasis was reported in 2%-40% of patients with antineutrophil cytoplasmic antibody-associated vasculitis (AAV), but there were no studies on the prevalence, risk factors and impact of AAV-associated bronchiectasis in Chinese patients. Research design and methods AAV patients were retrospectively enrolled. The clinical, laboratory and imaging features and the prognosis were analyzed and compared between those with and without bronchiectasis. Results Bronchiectasis was present in 48/212 (22.6%) of our AAV patients, among whom 41 were confirmed in 210 patients (19.5%) who received chest HRCT at the initial diagnosis of AAV. There were more women and fewer smokers in those with bronchiectasis as compared to those without. Cases with positive anti-MPO were more likely to have bronchiectasis (26.2%), and those with bronchiectasis were more likely to be anti-MPO positive (93.8%). Patients who had a diagnosis of bronchiectasis before AAV were more likely to have nervous system involvement, while patients without bronchiectasis had higher 24h proteinuria. The presence of bronchiectasis showed no significant effect on the 1, 3, 5-year survival. Conclusions Nearly 20% of patients showed bronchiectasis on chest HRCT at the initial diagnosis of AAV, and positivity of anti-MPO was associated with bronchiectasis in a Chinese cohort of AAV patients.","PeriodicalId":12103,"journal":{"name":"Expert Review of Respiratory Medicine","volume":"16 1","pages":"697 - 705"},"PeriodicalIF":3.9,"publicationDate":"2022-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42699409","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Socioeconomic determinants of respiratory health in patients with cystic fibrosis: implications for treatment strategies. 囊性纤维化患者呼吸系统健康的社会经济决定因素:对治疗策略的影响

IF 3.9 3区医学

Expert Review of Respiratory Medicine Pub Date : 2022-06-01 DOI: 10.1080/17476348.2022.2090928

Gabriela R Oates, Michael S Schechter

{"title":"Socioeconomic determinants of respiratory health in patients with cystic fibrosis: implications for treatment strategies.","authors":"Gabriela R Oates, Michael S Schechter","doi":"10.1080/17476348.2022.2090928","DOIUrl":"https://doi.org/10.1080/17476348.2022.2090928","url":null,"abstract":"Introduction: Great variation exists in the progression and outcomes of cystic fibrosis (CF) lung disease, due to both genetic and environmental influences. Social determinants mediate environmental exposures and treatment success; people with CF from socioeconomically disadvantaged backgrounds have worse health and die younger than those in more advantaged positions.Areas covered: This paper reviews the literature on the mechanisms that are responsible for generating and sustaining disparities in CF health, and the ways by which social determinants translate into health advantages or disadvantages in people with CF. The authors make recommendations for addressing social risk factors in CF clinical practice.Expert opinion: Socioeconomic factors are not dichotomous and their impact is felt at every step of the social ladder. CF care programs need to adopt a systematic protocol to screen for health-related social risk factors, and then connect patients to available resources to meet individual needs. Considerations such as daycare, schooling options, living and working conditions, and opportunities for physical exercise and recreation as well as promotion of self-efficacy are often overlooked. In addition, advocacy for changes in public policies on health insurance, environmental regulations, social welfare, and education would all help address the root causes of CF health inequities.","PeriodicalId":12103,"journal":{"name":"Expert Review of Respiratory Medicine","volume":"16 6","pages":"637-650"},"PeriodicalIF":3.9,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9329222/pdf/nihms-1818323.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9693757","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

What should the recommendations be for lifestyle factors in obstructive sleep apnea? 对于导致阻塞性睡眠呼吸暂停的生活方式因素应该有哪些建议?

IF 3.9 3区医学

Expert Review of Respiratory Medicine Pub Date : 2022-06-01 DOI: 10.1080/17476348.2022.2099377

Tianyi Huang

引用次数: 0

The prevalence of oropharyngeal dysphagia in patients with chronic obstructive pulmonary disease: a systematic review and meta-analysis 慢性阻塞性肺疾病患者口咽吞咽困难的患病率:系统回顾和荟萃分析

IF 3.9 3区医学

Expert Review of Respiratory Medicine Pub Date : 2022-05-04 DOI: 10.1080/17476348.2022.2086123

Wenyan Li, M. Gao, Jin Liu, Fengwa Zhang, Rongjing Yuan, Qingling Su, Yetong Wang, Yanhong Wang

{"title":"The prevalence of oropharyngeal dysphagia in patients with chronic obstructive pulmonary disease: a systematic review and meta-analysis","authors":"Wenyan Li, M. Gao, Jin Liu, Fengwa Zhang, Rongjing Yuan, Qingling Su, Yetong Wang, Yanhong Wang","doi":"10.1080/17476348.2022.2086123","DOIUrl":"https://doi.org/10.1080/17476348.2022.2086123","url":null,"abstract":"ABSTRACT Background Oropharyngeal dysphagia (OD) in chronic obstructive pulmonary disease (COPD) patients seriously influence the long-term prognosis of COPD patients. The aim of this study was to assess the prevalence and risk factors of OD in patients with COPD through a systematic review and meta-analysis of observational studies. Methods We identified all observational studies on the prevalence of OD in COPD patients by searching PubMed, Embase, the Cochrane Library, Web of Science, Cumulative Index to Nursing and Allied Health Literature (CINAHL), China National Knowledge Infrastructure (CNKI), the China Biomedical Literature Service System (CBM), the Wanfang Database, and the WeiPu (VIP) databases from database establishment to 1 December 2020. Results Results of the meta-analysis showed that the prevalence of OD in COPD patients was 32.7% (95%CI=30.1, 35.4, I2=91.5%). Dyspnea, gastroesophageal reflux disease(GERD), xerostomia, sputum bacteria, poor physical capacity, poor quality of life, and high CRP level are the risk factors for OD in COPD patients. Conclusion : The prevalence of OD in COPD patients is high. There were some differences in OD among COPD patients with different sex, ages, continents, evaluation methods, patient source and COPD exacerbation.","PeriodicalId":12103,"journal":{"name":"Expert Review of Respiratory Medicine","volume":"16 1","pages":"567 - 574"},"PeriodicalIF":3.9,"publicationDate":"2022-05-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44468655","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Lung transplantation for COVID-19 associated ARDS: patience is a virtue 肺移植治疗新冠肺炎相关ARDS：耐心是美德

IF 3.9 3区医学

Expert Review of Respiratory Medicine Pub Date : 2022-05-04 DOI: 10.1080/17476348.2022.2084383

A. Banga

引用次数: 0

Pulmonary fibrosis associated with rheumatoid arthritis: from pathophysiology to treatment strategies 与类风湿性关节炎相关的肺纤维化:从病理生理学到治疗策略

IF 3.9 3区医学

Expert Review of Respiratory Medicine Pub Date : 2022-05-04 DOI: 10.1080/17476348.2022.2089116

R. Diesler, V. Cottin

{"title":"Pulmonary fibrosis associated with rheumatoid arthritis: from pathophysiology to treatment strategies","authors":"R. Diesler, V. Cottin","doi":"10.1080/17476348.2022.2089116","DOIUrl":"https://doi.org/10.1080/17476348.2022.2089116","url":null,"abstract":"ABSTRACT Introduction Rheumatoid arthritis (RA) is the most common inflammatory autoimmune disease, characterized by symmetric destructive arthritis and synovitis. Lung involvement is frequent, including in the form of interstitial lung disease (ILD). RA-ILD often presents with a radiologic and pathologic pattern of usual interstitial pneumonia, similar to idiopathic pulmonary fibrosis, highlighting the similarities between the two diseases, but other patterns and pathological associations are described. Areas covered This article reviews the pathogenesis of pulmonary fibrosis in the setting of rheumatoid arthritis as well as the current and future therapeutic options. Expert opinion Pulmonary fibrosis in the setting of RA-ILD is an example of genotype–environment interaction and involves multiple mechanisms including autoimmunity, inflammation, and fibrogenesis. Although ILD conveys most of the exceeding mortality in RA patients, there are no official guidelines for the management of RA-ILD. Attention should be paid to potential lung toxicity of RA treatment even though some of them might help stabilize the ILD. Current standard of care is often composed of glucocorticoids that may be associated with immunosuppressive therapy. Following the approval of antifibrotic therapy for ILDs with a progressive fibrosing phenotype, current works are evaluating the benefit of such treatment in RA-ILD.","PeriodicalId":12103,"journal":{"name":"Expert Review of Respiratory Medicine","volume":"16 1","pages":"541 - 553"},"PeriodicalIF":3.9,"publicationDate":"2022-05-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48640264","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

Pathophysiology and clinical evaluation of the patient with unexplained persistent dyspnea. 原因不明的持续性呼吸困难患者的病理生理学和临床评估。

IF 2.9 3区医学

Expert Review of Respiratory Medicine Pub Date : 2022-05-01 Epub Date: 2022-01-20 DOI: 10.1080/17476348.2022.2030222

Andi Hudler, Fernando Holguin, Meghan Althoff, Anne Fuhlbrigge, Sunita Sharma

{"title":"Pathophysiology and clinical evaluation of the patient with unexplained persistent dyspnea.","authors":"Andi Hudler, Fernando Holguin, Meghan Althoff, Anne Fuhlbrigge, Sunita Sharma","doi":"10.1080/17476348.2022.2030222","DOIUrl":"10.1080/17476348.2022.2030222","url":null,"abstract":"Introduction: Dyspnea is a complex symptom, which largely results from an imbalance between an afferent sensory stimulus and the corresponding efferent respiratory neuromuscular response. In addition, it is heavily influenced by the patient's prior experiences and sociocultural factors.Areas covered: The diagnostic approach to these patients requires a graded, systematic, and often multidisciplinary approach to determine what is the underlying pathophysiologic process. Utilization of objective data obtained through lab testing, imaging, and advanced testing, such as cardiopulmonary exercise testing, is often required to help identify underlying pathology contributing to a patient's symptoms. This article will review dyspnea's underlying pathophysiological mechanisms and standardized approaches to diagnoses. In the expert opinion section, we will discuss our own clinical approach to evaluating patients with persistent dyspnea.Expert opinion: Unexplained dyspnea is a challenging diagnosis that occurs in patients with and without underlying cardiopulmonary diseases. It requires a systematic approach, which initially uses clinical evaluation in addition to standard imaging and clinical biomarkers. When diagnoses are not made during the initial evaluation, subsequent tests can include cardiopulmonary exercise test and methacholine challenge. To be certain of the correct diagnosis, It is imperative that the clinician determines dyspnea's response to a particular therapeutic intervention.","PeriodicalId":12103,"journal":{"name":"Expert Review of Respiratory Medicine","volume":"16 5","pages":"511-518"},"PeriodicalIF":2.9,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9276544/pdf/nihms-1776502.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9378898","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0