{"title":"The temporal heterogeneity of usual interstitial pneumonia on chest CT.","authors":"Ahmad Abu Qubo, Anjali Saqi, Mary M Salvatore","doi":"10.1080/17476348.2022.2130767","DOIUrl":null,"url":null,"abstract":"The temporal heterogeneity that is a part of the pathologic UIP diagnosis can also be observed on chest CT. Earliest CT features of UIP include sub-pleural, basilar predominant opacities, and traction bronchiectasis. Late UIP presents radiographically with honeycombing that tends to increase in its peripheral extent and thickness over time. Temporal heterogeneity is manifest on CT with isolated areas of traction bronchiectasis representing early disease and separate areas of honeycombing representing more advanced disease in the same patient. Furthermore, some patients evolve from a probable UIP pattern to a UIP pattern. Therefore, a probable UIP pattern with its traction bronchiectasis and absence of honeycombing is an early UIP pattern. The most important questions become \"Will it progress\" and \"Why should it not progress\"?","PeriodicalId":12103,"journal":{"name":"Expert Review of Respiratory Medicine","volume":null,"pages":null},"PeriodicalIF":2.9000,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Expert Review of Respiratory Medicine","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1080/17476348.2022.2130767","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2022/10/13 0:00:00","PubModel":"Epub","JCR":"Q2","JCRName":"RESPIRATORY SYSTEM","Score":null,"Total":0}
引用次数: 1
Abstract
The temporal heterogeneity that is a part of the pathologic UIP diagnosis can also be observed on chest CT. Earliest CT features of UIP include sub-pleural, basilar predominant opacities, and traction bronchiectasis. Late UIP presents radiographically with honeycombing that tends to increase in its peripheral extent and thickness over time. Temporal heterogeneity is manifest on CT with isolated areas of traction bronchiectasis representing early disease and separate areas of honeycombing representing more advanced disease in the same patient. Furthermore, some patients evolve from a probable UIP pattern to a UIP pattern. Therefore, a probable UIP pattern with its traction bronchiectasis and absence of honeycombing is an early UIP pattern. The most important questions become "Will it progress" and "Why should it not progress"?
期刊介绍:
Coverage will include the following key areas:
- Prospects for new and emerging therapeutics
- Epidemiology of disease
- Preventive strategies
- All aspects of COPD, from patient self-management to systemic effects of the disease and comorbidities
- Improved diagnostic methods, including imaging techniques, biomarkers and physiological tests.
- Advances in the treatment of respiratory infections and drug resistance issues
- Occupational and environmental factors
- Progress in smoking intervention and cessation methods
- Disease and treatment issues for defined populations, such as children and the elderly
- Respiratory intensive and critical care
- Updates on the status and advances of specific disease areas, including asthma, HIV/AIDS-related disease, cystic fibrosis, COPD and sleep-disordered breathing morbidity