European Journal of Radiology最新文献

{"title":"Impact of CT reconstruction algorithms on pericoronary and epicardial adipose tissue attenuation","authors":"Huawei Xiao ,&nbsp;Xiangquan Wang ,&nbsp;Panfeng Yang ,&nbsp;Ling Wang ,&nbsp;Jiada Xi ,&nbsp;Jian Xu","doi":"10.1016/j.ejrad.2025.112132","DOIUrl":"10.1016/j.ejrad.2025.112132","url":null,"abstract":"<div><h3>Objective</h3><div>This study aims to investigate the impact of adaptive statistical iterative reconstruction-Veo (ASIR-V) and deep learning image reconstruction (DLIR) algorithms on the quantification of pericoronary adipose tissue (PCAT) and epicardial adipose tissue (EAT). Furthermore, we propose to explore the feasibility of correcting the effects through fat threshold adjustment.</div></div><div><h3>Methods</h3><div>A retrospective analysis was conducted on the imaging data of 134 patients who underwent coronary CT angiography (CCTA) between December 2023 and January 2024. These data were reconstructed into seven datasets using filtered back projection (FBP), ASIR-V at three different intensities (ASIR-V 30%, ASIR-V 50%, ASIR-V 70%), and DLIR at three different intensities (DLIR-L, DLIR-M, DLIR-H). Repeated-measures ANOVA was used to compare differences in fat, PCAT and EAT attenuation values among the reconstruction algorithms, and Bland-Altman plots were used to analyze the agreement between ASIR-V or DLIR and FBP algorithms in PCAT attenuation values.</div></div><div><h3>Results</h3><div>Compared to FBP, ASIR-V 30 %, ASIR-V 50 %, ASIR-V 70 %, DLIR-L, DLIR-M, and DLIR-H significantly increased fat attenuation values (−103.91 ± 12.99 HU, −102.53 ± 12.68 HU, −101.14 ± 12.78 HU, −101.81 ± 12.41 HU, −100.87 ± 12.25 HU, −99.08 ± 12.00 HU vs. −105.95 ± 13.01 HU, all <em>p</em> &lt; 0.001). When the fat threshold was set at −190 to −30 HU, ASIR-V and DLIR algorithms significantly increased PCAT and EAT attenuation values compared to FBP algorithm (all <em>p</em> &lt; 0.05), with these values increasing as the reconstruction intensity level increased. After correction with a fat threshold of −200 to −35 HU for ASIR-V 30 %, −200 to −40 HU for ASIR-V 50 % and DLIR-L, and −200 to −45 HU for ASIR-V 70 %, DLIR-M, and DLIR-H, the mean differences in PCAT attenuation values between ASIR-V or DLIR and FBP algorithms decreased (−0.03 to 1.68 HU vs. 2.35 to 8.69 HU), and no significant difference was found in PCAT attenuation values between FBP and ASIR-V 30 %, ASIR-V 50 %, ASIR-V 70 %, DLIR-L, and DLIR-M (all <em>p</em> &gt; 0.05).</div></div><div><h3>Conclusion</h3><div>Compared to the FBP algorithm, ASIR-V and DLIR algorithms increase PCAT and EAT attenuation values. Adjusting the fat threshold can mitigate the impact of ASIR-V and DLIR algorithms on PCAT attenuation values.</div></div>","PeriodicalId":12063,"journal":{"name":"European Journal of Radiology","volume":"188 ","pages":"Article 112132"},"PeriodicalIF":3.2,"publicationDate":"2025-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143923264","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Predicting early recurrence in hepatocellular carcinoma after hepatectomy using GD-EOB-DTPA enhanced MRI-based model","authors":"Hanqiu Zeng ,&nbsp;Zichang Ma ,&nbsp;Yuxi Tao ,&nbsp;Ci Cheng ,&nbsp;Junyu Lin ,&nbsp;Jiayu Fang ,&nbsp;Yuhan Wei ,&nbsp;Huajin Liu ,&nbsp;Feixiang Zou ,&nbsp;Enming Cui ,&nbsp;Yaqin Zhang","doi":"10.1016/j.ejrad.2025.112130","DOIUrl":"10.1016/j.ejrad.2025.112130","url":null,"abstract":"<div><h3>Purpose</h3><div>To develop and validate a comprehensive model for predicting postoperative early recurrence of hepatocellular carcinoma (HCC) based on gadoxetate disodium (Gd-EOB-DTPA)-enhanced MRI.</div></div><div><h3>Methods</h3><div>239 patients with HCC who underwent curative surgical resection were recruited from two centers between April 2017 and December 2022. Radiomics features were extracted from the region of interest (ROI) on preoperative Gd-EOB-DTPA-enhanced MR images, and consistency analysis was performed to select stable radiomics features. Significant variables in the univariate and multivariate logistic regression analysis were included in clinical-radiologic model. Nomograms were constructed by combining the best performing radiologic and clinical-radiologic characteristics. Recurrence-free survival (RFS) comparisons were conducted using the log-rank test based on high versus low model-derived scores.</div></div><div><h3>Results</h3><div>The radiomics model based on multiple phases MR outperformed all other radiomics models and had the best discrimination for early recurrence, with AUC of 0.799 and 0.743 in the training and validation sets, respectively. In the entire cohort, high-risk patients exhibited significantly lower RFS compared to low-risk patients.</div></div><div><h3>Conclusion</h3><div>The nomogram integrating Gd-EOB-DTPA enhanced MRI radiomics features and clinical-radiologic characteristics demonstrate superior predictive performance with postoperative early recurrence in patients with HCC. The model can identify patients at high risk and provide support for individualized treatment planning.</div></div>","PeriodicalId":12063,"journal":{"name":"European Journal of Radiology","volume":"188 ","pages":"Article 112130"},"PeriodicalIF":3.2,"publicationDate":"2025-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143887502","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diagnostic performance and reproducibility of ACR Bone-RADS for the radiographic evaluation of potentially neoplastic bone lesions","authors":"Stefano Fusco ,&nbsp;Salvatore Gitto ,&nbsp;Ettore Palizzolo ,&nbsp;Letizia Di Meglio ,&nbsp;Francesca Serpi ,&nbsp;Domenico Albano ,&nbsp;Luca Maria Sconfienza ,&nbsp;Carmelo Messina","doi":"10.1016/j.ejrad.2025.112128","DOIUrl":"10.1016/j.ejrad.2025.112128","url":null,"abstract":"<div><h3>Objective</h3><div>To assess the diagnostic performance and the reproducibility of the American College of Radiology (ACR) Bone-RADS score for the radiographic evaluation of bone lesions.</div></div><div><h3>Materials and methods</h3><div>Patients with histologically proven bone lesion of the extremities and radiographs performed within three months prior to biopsy/surgery were retrospectively enrolled.</div><div>All radiographs were evaluated using ACR Bone-RADS scoring system by two musculoskeletal radiologists (Readers 1 and 2, with 10 and 3 years of experience in bone tumors imaging, respectively), and one junior general radiologist (Reader 3).</div><div>Percent agreement, Cohen’s Kappa and Conger’s Kappa were calculated for all score categories. Weighted-kappa and intraclass correlation coefficient (ICC) were computed for the final Bone-RADS score. Sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) were calculated based on the expert radiologist’s diagnosis, using histology as the reference standard.</div></div><div><h3>Results</h3><div>Final cohort consisted of 285 patients. Substantial to almost perfect agreement was found on almost all Bone-RADS categories. Moderate agreement was found for “endosteal scalloping” between Readers 1–3 (K = 0.59) and Readers 2–3 (K = 0.55). The score showed good diagnostic performance in discriminating between benign and potentially aggressive lesions (AUC = 0.82). Suboptimal sensitivity and NPV were found using a Bone-RADS ≥ 3 cut-off; if enchondroma and atypical cartilaginous tumors were excluded, diagnostic performance significantly improved (AUC = 0.92).</div></div><div><h3>Conclusion</h3><div>The ACR Bone-RADS score showed high reproducibility and good accuracy in identifying benign lesions.</div><div>In cases of cartilaginous tumors, the score may underestimate the disease, suggesting that additional imaging, rather than radiographic follow-up, could be considered for Bone-RADS-2 chondroid lesions.</div></div>","PeriodicalId":12063,"journal":{"name":"European Journal of Radiology","volume":"188 ","pages":"Article 112128"},"PeriodicalIF":3.2,"publicationDate":"2025-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143869246","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Non-contrast dual-energy CT iodine quantification for lung injury characterization after balloon pulmonary angioplasty","authors":"Alfredo Páez-Carpio ,&nbsp;Llúria Cornellas ,&nbsp;Blanca Domenech-Ximenos ,&nbsp;Elena Serrano ,&nbsp;Joan A. Barberà ,&nbsp;Fernando M. Gómez ,&nbsp;Isabel Blanco ,&nbsp;Ivan Vollmer","doi":"10.1016/j.ejrad.2025.112129","DOIUrl":"10.1016/j.ejrad.2025.112129","url":null,"abstract":"<div><div><em>Objectives</em>This study aimed to identify differences in iodine concentrations in new-onset pulmonary injuries and normal lung parenchyma after balloon pulmonary angioplasty (BPA) for chronic thromboembolic pulmonary hypertension (CTEPH) using non-contrast dual-energy CT (NC-DECT) between patients with pulmonary hemorrhage and reperfusion pulmonary edema.</div></div><div><h3>Methods</h3><div>Patients undergoing NC-DECT after BPA between January 2019 and April 2023 due to hemoptysis or clinical worsening were retrospectively evaluated for inclusion. Patients were divided based on the presence or absence of BPA-related hemoptysis. Intralesional iodine concentrations were measured in new-onset lung injuries, adjacent normal parenchyma, same lobe, and contralateral lung. CT morphological features, including lesion shape, imaging pattern, absolute density, and ROI size, were recorded. Statistical comparisons were performed using Mann-Whitney U, Friedman, and Wilcoxon signed-rank tests.</div></div><div><h3>Results</h3><div>Thirteen patients with 32 new-onset post-BPA lung injuries were included. Median iodine concentration in lung injuries was significantly higher in patients with hemoptysis than those without (3.4 mg/mL versus 0.6 mg/mL; <em>p</em> &lt; 0.001). In the hemoptysis group, iodine concentration in lung injuries was significantly higher compared with the different locations of normal lung parenchyma (<em>p</em> &lt; 0.001). In the non-hemoptysis group, no significant differences in iodine concentration were observed between lung injuries and normal parenchyma (<em>p</em> = 0.167; p = 0.351; <em>p</em> = 0.246). Absolute density (p = 0.767), lesion shape (p = 0.610), imaging appearance (p = 0.530), ROI area (p = 0.452), and halo sign (p = 0.810) showed no significant correlation with hemoptysis.</div></div><div><h3>Conclusion</h3><div>NC-DECT identifies iodine concentration differences in lung injuries between patients with and without hemoptysis after BPA. Elevated iodine concentrations may serve as an imaging marker for post-procedural pulmonary hemorrhage.</div></div><div><h3>Critical relevance statement</h3><div>This exploratory study demonstrates the potential of NC-DECT in distinguishing between pulmonary hemorrhage and reperfusion pulmonary edema in lung injuries after BPA in patients with CTEPH. The ability to quantify iodine concentrations in lung lesions offers a novel imaging biomarker for pulmonary hemorrhage, which could play a pivotal role in improving clinical decision-making and management strategies for patients undergoing BPA.</div></div>","PeriodicalId":12063,"journal":{"name":"European Journal of Radiology","volume":"187 ","pages":"Article 112129"},"PeriodicalIF":3.2,"publicationDate":"2025-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143855379","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Application of combi-elastography for follow-up after pediatric liver transplantation: A prospective study","authors":"Yang Gao ,&nbsp;Fenglin Xu ,&nbsp;Lirong Zhu ,&nbsp;Yi Tang ,&nbsp;Chunjiang Yang ,&nbsp;Juan Xu ,&nbsp;Zhi-Gang Wang ,&nbsp;Jingyu Chen","doi":"10.1016/j.ejrad.2025.112127","DOIUrl":"10.1016/j.ejrad.2025.112127","url":null,"abstract":"<div><h3>Objective</h3><div>To investigate the use of combi-elastography in children after liver transplantation.</div></div><div><h3>Methods</h3><div>Thirty-five children who underwent liver transplantation at our hospital were prospectively selected. Donor livers were divided into fatty liver and nonfatty liver groups according to the degree of fatty liver. Recipients were categorized into groups with (10 patients) and without complications (25 patients) according to the presence or absence of complications within 6 months after surgery. Combi-elastography was performed on each donor liver, and each patient underwent combi-elastography at the time of surgery and at 1 day, 7 days, 1 month, 3 months, and 6 months after surgery; the results of liver function tests were recorded at the same time points.</div></div><div><h3>Results</h3><div>Despite the rapid recovery of liver function in the group without complications, the combi-elastography indices were still high in the early stage and gradually stabilized after 3 months but were still higher than those of the donor liver at 6 months. In the fatty liver group, the postoperative 1-day combi-elastography values were significantly higher than those in the nonfatty liver group, and in the group with complications, the postoperative 1-day combi-elastography values were significantly higher than those in the group without complications. The receiver operating characteristic (ROC) curve analysis revealed that the areas under the curves (AUCs) of the combi-elastography values for predicting complications in children at 6 months after liver transplantation were 8.41 kPa for Young’s modulus (E) (with a sensitivity of 90 % (9/10 and a specificity of 76 % (19/25)) 1.26 for the F-index (FI) value (sensitivity 80 %(8/10), specificity 80 % (20/25)), and 1.05 kPa for the A-index (AI) value (sensitivity 80 %(8/10), specificity 72 % (18/25)).</div></div><div><h3>Conclusions</h3><div>Combi-elastography is useful for assessing changes in liver stiffness in the early period after liver transplantation and should therefore be considered for the follow-up of children who undergo liver transplantation.</div></div>","PeriodicalId":12063,"journal":{"name":"European Journal of Radiology","volume":"188 ","pages":"Article 112127"},"PeriodicalIF":3.2,"publicationDate":"2025-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143876941","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prediction of early recurrence in primary central nervous system lymphoma based on multimodal MRI-based radiomics: A preliminary study","authors":"Xiaochen Wang ,&nbsp;Sihui Wang ,&nbsp;Xuening Zhao ,&nbsp;Lingxu Chen ,&nbsp;Mengyuan Yuan ,&nbsp;Ying Yan ,&nbsp;Xuefei Sun ,&nbsp;Yuanbo Liu ,&nbsp;Shengjun Sun","doi":"10.1016/j.ejrad.2025.112125","DOIUrl":"10.1016/j.ejrad.2025.112125","url":null,"abstract":"<div><h3>Objectives</h3><div>To evaluate the role of multimodal magnetic resonance imaging radiomics features in predicting early recurrence of primary central nervous system lymphoma (PCNSL) and to investigate their correlation with patient prognosis.</div></div><div><h3>Materials and methods</h3><div>A retrospective analysis was conducted on 145 patients with PCNSL who were treated with high-dose methotrexate-based chemotherapy. Clinical data and MRI images were collected, with tumor regions segmented using ITK-SNAP software. Radiomics features were extracted via Pyradiomics, and predictive models were developed using various machine learning algorithms. The predictive performance of these models was assessed using receiver operating characteristic (ROC) curves. Additionally, Cox regression analysis was employed to identify risk factors associated with progression-free survival (PFS).</div></div><div><h3>Results</h3><div>In the cohort of 145 PCNSL patients (72 recurrence, 73 non-recurrence), clinical characteristics were comparable between groups except for multiple lesion frequency (61.1% vs. 39.7%, p &lt; 0.05) and not receiving consolidation therapy (44.4% vs. 13.7%, p &lt; 0.05). A total of 2392 radiomics features were extracted from CET1 and T2WI MRI sequence. Combining clinical variables, 10 features were retained after the feature selection process. The logistic regression (LR) model exhibited superior predictive performance in the test set to predict PCNSL early relapse, with an area under the curve (AUC) of 0.887 (95 % confidence interval: 0.785–0.988). Multivariate Cox regression identified the Cli-Rad score as an independent prognostic factor for PFS. Significant difference in PFS was observed between high- and low-risk groups defined by Cli-Rad score (8.24 months vs. 24.17 months, p &lt; 0.001).</div></div><div><h3>Conclusions</h3><div>The LR model based on multimodal MRI radiomics and clinical features, can effectively predict early recurrence of PCNSL, while the Cli-Rad score could independently forecast PFS among PCNSL patients.</div></div>","PeriodicalId":12063,"journal":{"name":"European Journal of Radiology","volume":"188 ","pages":"Article 112125"},"PeriodicalIF":3.2,"publicationDate":"2025-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143887499","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Conditions at risk of pancreatic cancer: The radiology perspective","authors":"Roberto Cannella ,&nbsp;Marco Dioguardi Burgio ,&nbsp;Cesare Maino ,&nbsp;Francesco Matteini ,&nbsp;Davide Ippolito ,&nbsp;Piero Boraschi ,&nbsp;Giulia A. Zamboni ,&nbsp;Federica Vernuccio","doi":"10.1016/j.ejrad.2025.112119","DOIUrl":"10.1016/j.ejrad.2025.112119","url":null,"abstract":"<div><div>Pancreatic cancer remains one for the most aggressive cancer worldwide, with pancreatic ductal adenocarcinoma being the most common malignant pancreatic lesion, associated with poor prognosis. While surgical resection is the only curative treatment, only a minority of patients is eligible for surgery due to its diagnosis at advanced stages. Therefore, strategies for early detection of pancreatic cancer are needed. This article aims to provide a state-of-the-art review of the most common conditions associated to an increased risk of pancreatic cancer. Conditions linked to risk of pancreatic cancer development include certain pancreato-biliary anatomical variants, intraductal papillary mucinous neoplasms, mucinous cystic neoplasm, and familial pancreatic cancer with specific genetic mutations. Early imaging signs of pancreatic cancer can also be incidentally encountered on CT or MRI performed for other indications and they should be promptly recognized by the radiologists in order to avoid delays in the diagnosis. The features include focal pancreatic atrophy, contour deformity, dilation of the main pancreatic duct (MPD), changes in the caliber of the MPD, abrupt interruption of the MPD, and biliary tree dilation. MRI with the adoption of abbreviated protocols has been increasingly evaluated for the follow-up of cystic lesions. Although screening of the general population is not recommended due to the low incidence and high costs, surveillance with MRI can be considered in selected high-risk individuals.</div></div>","PeriodicalId":12063,"journal":{"name":"European Journal of Radiology","volume":"188 ","pages":"Article 112119"},"PeriodicalIF":3.2,"publicationDate":"2025-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143864646","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Radiation dose reduction and image quality enhancement for patients unable to elevate their arms in chest CT: A comparative study","authors":"Ki Baek Lee ,&nbsp;Seong Min Kim ,&nbsp;Jong-Tae Yoon ,&nbsp;Yura Ahn ,&nbsp;Kyung-Hyun Do","doi":"10.1016/j.ejrad.2025.112120","DOIUrl":"10.1016/j.ejrad.2025.112120","url":null,"abstract":"<div><h3>Purpose</h3><div>To propose a method to effectively reduce radiation dose while enhancing image quality in chest CT for patients unable to elevate their arms utilizing the air–gap technique.</div></div><div><h3>Methods</h3><div>Chest CT images were acquired in three positions: arms raised (control group, position A), arms lowered with the air–gap technique utilizing an in-house device (position B), and arms lowered without the device (position C). Data were categorized by body weight. Radiation dose was assessed using dose-length product (DLP) values, with quantitative analyses of image noise, contrast-to-noise ratio (CNR), and CNR-to-dose ratio (CNRDR). Qualitative assessment utilized a Likert scale.</div></div><div><h3>Results</h3><div>Average DLP was 473.7 ± 142.9 mGy × cm in position C, with the lowest in position A at 267.3 ± 93.3 mGy × cm. Position B had a DLP of 317.2 ± 121.4 mGy × cm, 18.7 % higher than position A but 33.0 % lower than position C. In patients over 70 kg, all positions exceeded the thoracic CT diagnostic reference level (DRL) (324.2 mGy × cm). For those under 70 kg (i.e., &lt;50 kg, 50–70 kg), position B showed lower DLPs compared to the above DRL. Quantitative analysis indicated that position B maintained image quality similar to position A, with CNRDR of 30.2 ± 11.1 versus 26.6 ± 10.9 in position A, showing marginal significance (p = 0.046). The qualitative evaluation indicated that position A had the highest rating at 4.96, followed by position B at 4.51, and position C at 3.47.</div></div><div><h3>Conclusion</h3><div>The air–gap device with lowered arms during chest CT for patients unable to elevate their arms can reduce radiation dose while maintaining image quality. A custom-designed device facilitates safe and efficient procedures, especially for patients with higher body weight.</div></div>","PeriodicalId":12063,"journal":{"name":"European Journal of Radiology","volume":"188 ","pages":"Article 112120"},"PeriodicalIF":3.2,"publicationDate":"2025-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143875066","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"PRECISE framework: Enhanced radiology reporting with GPT for improved readability, reliability, and patient-centered care","authors":"Satvik Tripathi ,&nbsp;Liam Mutter ,&nbsp;Meghana Muppuri ,&nbsp;Suhani Dheer ,&nbsp;Emiliano Garza-Frias ,&nbsp;Komal Awan ,&nbsp;Aakash Jha ,&nbsp;Michael Dezube ,&nbsp;Azadeh Tabari ,&nbsp;Bernardo C. Bizzo ,&nbsp;Keith J. Dreyer ,&nbsp;Christopher P. Bridge ,&nbsp;Dania Daye","doi":"10.1016/j.ejrad.2025.112124","DOIUrl":"10.1016/j.ejrad.2025.112124","url":null,"abstract":"<div><h3>Background</h3><div>The PRECISE framework, defined as Patient-Focused Radiology Reports with Enhanced Clarity and Informative Summaries for Effective Communication, leverages GPT-4 to create patient-friendly summaries of radiology reports at a sixth-grade reading level.</div></div><div><h3>Purpose</h3><div>The purpose of the study was to evaluate the effectiveness of the PRECISE framework in improving the readability, reliability, and understandability of radiology reports. We hypothesized that the PRECISE framework improves the readability and patient understanding of radiology reports compared to the original versions.</div></div><div><h3>Materials and Methods</h3><div>The PRECISE framework was assessed using 500 chest X-ray reports. Readability was evaluated using the Flesch Reading Ease, Gunning Fog Index, and Automated Readability Index. Reliability was gauged by clinical volunteers, while understandability was assessed by non-medical volunteers. Statistical analyses including t-tests, regression analyses, and Mann-Whitney U tests were conducted to determine the significance of the differences in readability scores between the original and PRECISE-generated reports.</div></div><div><h3>Results</h3><div>Readability scores significantly improved, with the mean Flesch Reading Ease score increasing from 38.28 to 80.82 (p-value &lt; 0.001), the Gunning Fog Index decreasing from 13.04 to 6.99 (p-value &lt; 0.001), and the ARI score improving from 13.33 to 5.86 (p-value &lt; 0.001). Clinical volunteer assessments found 95 % of the summaries reliable, and non-medical volunteers rated 97 % of the PRECISE-generated summaries as fully understandable.</div></div><div><h3>Conclusion</h3><div>The application of the PRECISE approach demonstrates promise in enhancing patient understanding and communication without adding significant burden to radiologists. With improved reliability and patient-friendly summaries, this approach holds promise for fostering patient engagement and understanding in healthcare decision-making. The PRECISE framework represents a pivotal step towards more inclusive and patient-centric care delivery.</div></div>","PeriodicalId":12063,"journal":{"name":"European Journal of Radiology","volume":"187 ","pages":"Article 112124"},"PeriodicalIF":3.2,"publicationDate":"2025-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143868020","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Novel approach to MRI based risk stratification of uterine myometrial lesions","authors":"Eva Zlotykamien-Taieb ,&nbsp;Diana Gherman ,&nbsp;Rana Al Rouhban ,&nbsp;Marie Florin ,&nbsp;Emile Darai ,&nbsp;Bassam Haddad ,&nbsp;Yohann Dabi ,&nbsp;Safaa Arbel ,&nbsp;Priyanka Jha ,&nbsp;Isabelle Thomassin-Naggara","doi":"10.1016/j.ejrad.2025.112126","DOIUrl":"10.1016/j.ejrad.2025.112126","url":null,"abstract":"&lt;div&gt;&lt;h3&gt;Background&lt;/h3&gt;&lt;div&gt;Surgery for uterine mesenchymal tumors is common in gynecology. Preoperative diagnosis of malignant tumors can lead to appropriate management for the lesions.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Purpose&lt;/h3&gt;&lt;div&gt;This study aims to externally validate a previous MRI-based expert consensus algorithm and evaluate the potential modification of MR-based scoring system’s accuracy in diagnosing uterine mesenchymal tumors (UMT).&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Material and methods&lt;/h3&gt;&lt;div&gt;With institutional ethics committee approval and a waiver of informed consent (CRM-2405–410), a bicentric retrospective observational cohort study was conducted from January 2018 to December 2023. The study included women with a pathological diagnosis of uterine mesenchymal tumor following a pelvic MRI within six months. Clinical and MR criteria were blindly recorded by two radiologists (6- and 3-years’ experience in gynaecological MR imaging) who assessed several MR features. Continuous variables were analyzed using a Mann–Whitney test, and categorical variables using Fisher’s exact test. Odds ratios (OR) for predicting malignancy were calculated with 95% confidence intervals and p-values.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Results&lt;/h3&gt;&lt;div&gt;The cohort included 455 women (mean age: 43 years, range: 15–82 years) with mesenchymal tumors: 437 leiomyomas, 2 STUMPs (0.4 %), and 16 malignant UMT (3.5 %). Using initial criteria (enlarged pelvic lymph nodes, T2W signal intensity, DW signal intensity compared to endometrium, and ADC cutoff value of 0.9 × 10&lt;sup&gt;−3&lt;/sup&gt; mm&lt;sup&gt;2&lt;/sup&gt;/sec), the model accurately classified 421 out of 455 cases (Accuracy: 92,5% (CI 93,1–94,3) and missed with 7 tumors (5 leiomyosarcomas, 2 STUMP). The sensitivity was 61.1 % (CI95% 38.5–83.6) and specificity was 93.8 % (CI95% 91.2–95.8) A modified algorithmic approach added “irregular tumor margins” and menopausal status, modified DW signal compared to bladder, and an elevated ADC cutoff value of 1.23 × 10&lt;sup&gt;−3&lt;/sup&gt; mm&lt;sup&gt;2&lt;/sup&gt;/sec, improving classification to 446 out of 455 cases (Accuracy: 98 % (CI95% 97.1 %-98.1 %) with only 3 missed tumors (2 STUMP and one leiomyosarcoma). The sensitivity was 83.3 % (CI95% 79–88) and specificity was 98.6 % (CI95% 98–99). The new algorithm significantly improved accuracy (p = 0.001), allowing the development of a 5-category scoring system.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Conclusion&lt;/h3&gt;&lt;div&gt;Modified MR imaging evaluation algorithms increase true positive diagnosis of malignant UMTs leading to effective differentiation from benign leiomyomas. The new algorithm can allow for appropriate triage of potentially malignant UMTs, alleviating risk associated with morcellation in patients with uterine leiomyosarcoma.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Summary&lt;/h3&gt;&lt;div&gt;Our study demonstrates that combining 5 criteria based on multivariate analysis in a new algorithm (T2W signal, DW signal, ADC cut off value of 1.23 x 10–3 mm2/sec, tumor margins and menopausal status) allows us to distinguish benign from mal","PeriodicalId":12063,"journal":{"name":"European Journal of Radiology","volume":"187 ","pages":"Article 112126"},"PeriodicalIF":3.2,"publicationDate":"2025-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143860462","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}