European Journal of Radiology最新文献

{"title":"Economic evaluation of bulk packaging and single-dose packaging of contrast media for contrast-enhanced CT","authors":"Jie Jia ,&nbsp;Yuxin Peng ,&nbsp;Zhixu Zhu ,&nbsp;Dunming Xiao ,&nbsp;Yingyao Chen ,&nbsp;Yan Wei","doi":"10.1016/j.ejrad.2026.112665","DOIUrl":"10.1016/j.ejrad.2026.112665","url":null,"abstract":"<div><h3>Objective</h3><div>To conduct an economic evaluation of bulk-packaged contrast media in the CT rooms from multiple perspectives, assess its economic benefits, and provide a evidence to support hospital cost control and pharmacy management.</div></div><div><h3>Methods</h3><div>Based on on-site investigations and the database constructed by the hospital management information system, information from 1,169 patients regarding contrast media utilization and medical insurance reimbursements was analyzed. We assessed the impact of different contrast media packaging formats on the hospital’s scanning volume and waste disposal costs using descriptive statistical methods and a decision-tree mode. In addition, cost-minimization analysis was conducted for the economic evaluation.</div></div><div><h3>Results</h3><div>Based on the average number of scans per hospital (49,807 per year), the 500 ml (400 mg/ml) vial saved an average of 29.60 s per patient compared with the 100 ml (400 mg/ml) vial, resulting in an annual increase of 3,890 patients scanned and potentially generating additional hospital revenue of approximately US$424,163, assuming sufficient appointment availability and operational capacity. In addition, the 500 ml (400 mg/ml) vial reduced medical insurance expenditures by US$1,701,280 to US$1,804,260 annually per hospital (a reduction of 52.19%–55.38%). The switch to bulk packaging also reduced medical waste by an average of 3,832 kg per year, corresponding to savings of US$1,904 in waste disposal costs. Qualitative interview indicated that imaging bulk-packaged contrast media can simultaneously reduce hospital costs and maintain patient safety under current technological conditions.</div></div><div><h3>Conclusion</h3><div>The use of bulk-packaged contrast media in contrast-enhanced CT was shown to be more effective in controlling hospital costs compared with single-dose packaging.</div></div>","PeriodicalId":12063,"journal":{"name":"European Journal of Radiology","volume":"196 ","pages":"Article 112665"},"PeriodicalIF":3.3,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145975425","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A comprehensive quantitative and qualitative assessment of TGSE-BLADE DWI in postoperative imaging following intracranial tumor resection","authors":"Christer Ruff ,&nbsp;Till-Karsten Hauser ,&nbsp;Paula Bombach ,&nbsp;Daniel Vogl ,&nbsp;Constantin Roder ,&nbsp;Frank Paulsen ,&nbsp;Deborah Staber ,&nbsp;Vivien Richter ,&nbsp;Leonie Zerweck ,&nbsp;Ulrike Ernemann ,&nbsp;Georg Gohla","doi":"10.1016/j.ejrad.2026.112659","DOIUrl":"10.1016/j.ejrad.2026.112659","url":null,"abstract":"<div><h3>Purpose</h3><div>Postoperative MRI plays a pivotal role in assessing residual disease and planning therapy after intracranial tumor resection. As acute perioperative infarction may mimic enhancing and non-enhancing tumor tissue in follow-up imaging, the initial postoperative MRI examination is essential for this purpose. However, conventional DWI techniques like RESOLVE are often impaired by artifacts from intracranial air. This study compares RESOLVE DWI with TGSE-BLADE DWI within early postoperative scans to improve diagnostic confidence in identifying ischemic changes.</div></div><div><h3>Method</h3><div>In a retrospective, institutional review board–approved study, 33 patients (mean age 52.3 ± 25.1 years) underwent a 1.5-Tesla MRI within 48 h of resection. RESOLVE and TGSE-BLADE DWI sequences were acquired in the same orientation and slice thickness of 5 mm. Two neuroradiologists blindly evaluated geometric distortion, susceptibility artifacts, overall image quality, and diagnostic confidence. Quantitative analysis included measuring signal-to-noise ratio (SNR), contrast-to-noise ratio (CNR), apparent diffusion coefficient (ADC) values, image quality metrics and resection defect dimensions against T1-weighted images.</div></div><div><h3>Results</h3><div>TGSE-BLADE DWI exhibited significantly reduced geometric distortions and susceptibility artifacts near the resection site compared with RESOLVE DWI, producing superior qualitative image quality and diagnostic confidence (p &lt; 0.001). Conversely, RESOLVE DWI yielded slightly higher SNR and CNR. Measurements of the resection defect on TGSE-BLADE DWI closely matched those on T1-weighted images (p = 0.974), while RESOLVE DWI showed a significant discrepancy (p &lt; 0.001).</div></div><div><h3>Conclusions</h3><div>TGSE-BLADE DWI significantly minimizes artifacts and geometric distortions in intracranial postoperative imaging, thereby improving the detection of perioperative ischemic changes. This robust technique serves as an effective alternative to conventional EPI-based sequences in challenging settings with pronounced B₀ inhomogeneities, ultimately enhancing diagnostic confidence and patient care.</div></div>","PeriodicalId":12063,"journal":{"name":"European Journal of Radiology","volume":"196 ","pages":"Article 112659"},"PeriodicalIF":3.3,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145975350","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of DSA-based postoperative cerebral blood flow cascades on outcomes in acute ischemic stroke patients undergoing successful endovascular thrombectomy","authors":"Jin Liu ,&nbsp;Chen Gong ,&nbsp;Yuetao Wen ,&nbsp;Jing Guo ,&nbsp;Junling Fu ,&nbsp;You Wang ,&nbsp;Jinxian Yuan ,&nbsp;Tao Xu ,&nbsp;Lina Zhang ,&nbsp;Shuyu Jiang","doi":"10.1016/j.ejrad.2026.112664","DOIUrl":"10.1016/j.ejrad.2026.112664","url":null,"abstract":"<div><h3>Background</h3><div>Half of patients with acute ischemic stroke caused by large vessel occlusion (AIS-LVO) fail to achieve functional independence after endovascular treatment (EVT), which may be related to the ineffective restoration of cerebral blood flow in ischemic brain tissue despite revascularization. Therefore, a comprehensive model to assess postoperative cerebral blood flow cascade (pCBF) may provide additional information for treatment.</div></div><div><h3>Methods</h3><div>This was a retrospective cohort study. All patients underwent standard cerebral angiography immediately after EVT. pCBF consisted of expanded Thrombolysis in Cerebral Infarction, microvascular cerebral circulation time, and Cortical Vein Opacification Score based on immediate DSA images after EVT. The primary outcome was functional independence at 90 days, defined as an mRS score of 0–2.</div></div><div><h3>Results</h3><div>156 patients were enrolled in this study after strict screening. In multivariate regression analysis, compared with the unfavorable pCBF group, the favorable pCBF group had a higher rate of functional independence at 90 days (82.1 % vs 26.0 %, aOR 12.94, 95 % CI 5.28–31.73, P &lt; 0.001). In addition, the pCBF demonstrated good discrimination and calibration in this cohort, as well as the fivefold cross-validation.</div></div><div><h3>Conclusion</h3><div>Favorable pCBF may better reflect true reperfusion in AIS-LVO patients after achieving successful recanalization and was associated with functional outcomes.</div></div>","PeriodicalId":12063,"journal":{"name":"European Journal of Radiology","volume":"196 ","pages":"Article 112664"},"PeriodicalIF":3.3,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145975351","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Radiation segmentectomy for treatment of hepatic oligometastases greater than 3 cm","authors":"Qian Yu ,&nbsp;Ali Ahmed ,&nbsp;Wali Badar ,&nbsp;Daniel Kwak ,&nbsp;Aaron William Lyon ,&nbsp;Yating Wang ,&nbsp;Carla Harmath ,&nbsp;Mikin Patel ,&nbsp;Divya Kumari ,&nbsp;Thuong Van Ha ,&nbsp;Osman Ahmed","doi":"10.1016/j.ejrad.2026.112657","DOIUrl":"10.1016/j.ejrad.2026.112657","url":null,"abstract":"<div><h3>Purpose</h3><div>The effectiveness of percutaneous thermoablation as curative treatment of hepatic oligometastases greater than 3 cm can be limited by the ability to achieve adequate ablation coverage. Radiation segmentectomy (RS) using yttrium-90 (Y90) microspheres is an established treatment and potentially curative for hepatocellular carcinoma (HCC) up to 8 cm. This study evaluates the safety and effectiveness of RS for secondary liver tumors larger than 3 cm.</div></div><div><h3>Methods</h3><div>A retrospective review at a single institution was performed from December 2017 to February 2024 to include patients treated with transarterial radioembolization (TARE) for liver metastases using glass Y90 microspheres. RS was defined as a target dose &gt; 200 Gy to no more than two liver segments. The following outcomes were retrieved: overall survival (OS), radiologic response, progression-free survival (PFS), adverse events, and 3-month serum toxicity.</div></div><div><h3>Results</h3><div>A total of 14 patients (mean age: 64.2 ± 18.5, M:F = 5:9) with secondary liver tumors (mean diameter: 4.7 ± 1.4 cm; single hepatic lesion: 57.1 %[8/14]), including 5 colorectal cancer (35.7 %), 2 renal cell carcinoma (14.3 %), 2 uveal melanoma (14.3 %), 2 adenoid cystic carcinoma (14.3 %), 1 pancreatic adenocarcinoma (7.1 %), 1 endometrial carcinoma (7.1 %), and 1 tonsillar adenocarcinoma (7.1 %). The mean segmentectomy dose was 352.6 ± 149.1 Gy. Response rate and disease control rate were 42.9 % (6/14) and 85.7 % (12/14), respectively. The 1-yr and 3-yr target tumor response rates were 51.4 % (95 %CI: 21.9–74.8 %) and 34.2 % (95 %CI: 7.1–64.9 %), respectively, with a median PFS of 16.3 months 95 %CI: 5.4 months-not reached). The 1-yr and 3-yr OS were 80.8 % (95 %CI: 42.4–94.9 %) and 40.4 % (95 %CI: 9.8–70.2 %), respectively, with a median OS of 24.3 months (95 %CI: 8.9-not reached). One patient developed grade 3 thrombocytopenia, requiring holding of systemic treatment (7.1 %). No additional grade 3 or above adverse events occurred.</div></div><div><h3>Conclusion</h3><div>Preliminary results suggest that RS is a feasible treatment option for secondary liver tumors &gt; 3 cm with few major adverse events.</div></div>","PeriodicalId":12063,"journal":{"name":"European Journal of Radiology","volume":"196 ","pages":"Article 112657"},"PeriodicalIF":3.3,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146035314","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Relationship between resource utilization and diagnostic accuracy of large language models for efficient multimodal reasoning in radiologic image interpretation","authors":"Taewon Han ,&nbsp;Jeong Hyun Lee ,&nbsp;Woo Kyoung Jeong,&nbsp;Jaeseung Shin,&nbsp;Yun Hwa Roh,&nbsp;Min Je Kim","doi":"10.1016/j.ejrad.2026.112677","DOIUrl":"10.1016/j.ejrad.2026.112677","url":null,"abstract":"<div><h3>Objectives</h3><div>We evaluated the diagnostic performance and resource efficiency of three multimodal-reasoning-models for radiological image interpretation.</div></div><div><h3>Methods</h3><div>Using three multimodal-reasoning-models, we analyzed 73 cases under different conditions (Imaging-Only and Combined-Descriptive-Text) with three system prompt types (basic [without system prompt], original [specialized-role], and chain-of-thought [CoT] prompts). Quiz cases were extracted from the Korean Society of Ultrasound in Medicine Website, along with corresponding human benchmark data. Diagnostic performance was assessed through Multiple-Choice (MCQ) and Differential-Diagnosis (DDx) outputs. Resource utilization was measured by token consumption for each case across all scenarios. Pearson correlation coefficients were calculated to evaluate associations between token usage and diagnostic accuracy.</div></div><div><h3>Results</h3><div>For imaging-only input, under CoT prompt, o1 demonstrated superior accuracy of 56.2 %, surpassing the 55.9 % human benchmark compared to Claude-3.7-Sonnet (49.3 %) and Gemini-2.0-Flash-Thinking-Experimental (37 %) for MCQ. The integration of descriptive-text inputs substantially increased performance across all models, with o1 achieving the highest accuracy (71.2 %, with basic and original). This performance advantage was most pronounced in DDx. Original prompts utilized fewer output tokens while maintaining comparable accuracy for o1 (Imaging-Only with DDx: original vs. basic, CoT prompts, all p &lt; 0.01). Intra-model analysis revealed a negative correlation between accuracy and output token for o1 (r = -0.41), while inter-model analysis showed strong positive correlations between total token and accuracy (r = 0.93 for Imaging-Only with MCQ).</div></div><div><h3>Conclusion</h3><div>The paradoxical relationship between resource utilization and diagnostic accuracy suggests that model architecture fundamentally determines baseline performance, while prompt optimization influences efficiency within architectural constraints on multimodal-reasoning-models.</div></div>","PeriodicalId":12063,"journal":{"name":"European Journal of Radiology","volume":"196 ","pages":"Article 112677"},"PeriodicalIF":3.3,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146035636","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prospective evaluation of artificial intelligence (AI) in lumbar spine magnetic resonance imaging (MRI) workflow: from deep learning (DL)-enhanced accelerated acquisition to simultaneous vision-language model (VLM)-based automated report generation","authors":"Jiwoo Park ,&nbsp;Kyunghwa Han ,&nbsp;Ji Seon Oh ,&nbsp;Hee Dong Chae ,&nbsp;Ahram Kim ,&nbsp;Si Young Park ,&nbsp;Hye Jin Yoo ,&nbsp;Young Han Lee","doi":"10.1016/j.ejrad.2026.112695","DOIUrl":"10.1016/j.ejrad.2026.112695","url":null,"abstract":"<div><h3>Objectives</h3><div>To evaluate the diagnostic interchangeability of DL-enhanced accelerated lumbar (L)-spine magnetic resonance imaging (MRI) with conventional imaging and to assess the diagnostic agreement and feasibility of vision-language-model (VLM)-based automated reporting.</div></div><div><h3>Methods</h3><div>The Institutional Review Boards oftwo participating institutions approved this prospective study. Seventy patients were enrolled from these two institutions. All the participants underwent both conventional and accelerated L-spine MRI during the same session, resulting in 140 MRI scans. Quantitative analyses included signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR), whereas qualitative image quality assessments were conducted by four radiologists blinded to the scan type and patient information. The interchangeability between conventional and accelerated MRI with DL-based enhancement protocols was evaluated for five key pathologic findings. Automated structured reports were generated using a commercially available VLM-based spine interpretation software and compared with radiologist consensus reports. Statistical analyses were performed, with <em>p</em> &lt; 0.05 considered statistically significant.</div></div><div><h3>Results</h3><div>Accelerated L-spine MRI with DL-based enhancement reduced the acquisition time by approximately 80–86% when compared with conventional MRI, while maintaining diagnostic interchangeability. Quantitative analyses revealed superior SNRs and CNRs, and qualitative evaluations supported comparable image quality. Automated reporting demonstrated substantial to almost perfect agreement across key pathologies.</div></div><div><h3>Conclusions</h3><div>DL-enhanced accelerated MRI produced high-quality diagnostic images within 2 min, and VLM-based automated reporting demonstrated strong agreement with the radiologists. These findings provide prospective evidence supporting the clinical feasibility of integrating AI into both the acquisition and interpretation workflows in L-spine MRI, with the potential to enhance the efficiency, consistency, and scalability of musculoskeletal imaging.</div></div>","PeriodicalId":12063,"journal":{"name":"European Journal of Radiology","volume":"196 ","pages":"Article 112695"},"PeriodicalIF":3.3,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146035638","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of diagnostic capability and subtypes classification for inguinal hernias between upright and supine ADCTs","authors":"Masahiko Nomura ,&nbsp;Takeshi Yoshikawa ,&nbsp;Takahiro Ueda ,&nbsp;Yoshiyuki Ozawa ,&nbsp;Hirona Kimata ,&nbsp;Yuya Ito ,&nbsp;Kenji Fujii ,&nbsp;Naruomi Akino ,&nbsp;Daisuke Takenaka ,&nbsp;Yoshiharu Ohno","doi":"10.1016/j.ejrad.2025.112647","DOIUrl":"10.1016/j.ejrad.2025.112647","url":null,"abstract":"<div><h3>Purpose</h3><div>The purpose of this study was to directly compare diagnostic capability of inguinal herniation between upright area-detector CT (ADCT) and conventional supine ADCT under the Valsalva maneuver.</div></div><div><h3>Materials and methods</h3><div>This retrospective study included 209 patients with 360 inguinal herniations and 123 patients without inguinal hernias. All patients underwent supine and upright ADCT for the evaluation of abdominal wall hernias within one week between May 2023 and March 2024. From this cohort, a total of 120 of 360 inguinal hernias and 120 of 304 non-inguinal hernias were computationally selected, and the probability of hernia was visually assessed by two board-certified general and abdominal radiologists with 5-point scales to assess subtypes of herniation. The final score for each hernia was determined as consensus of two investigators. To determine the capability of diagnosis for inguinal herniation in selected lesion groups, diagnostic performance was compared between upright and supine ADCTs using an ROC analysis. Then, sensitivity (SE), specificity (SP), and accuracy (AC) for differentiation of inguinal from non-inguinal hernias were compared between the two methods using McNemar’s test.</div></div><div><h3>Results</h3><div>The area under the curve (AUC) of upright ADCT (AUC = 0.96) was significantly larger than that of supine ADCT (AUC = 0.93, p &lt; 0.0001). Sensitivity (SE) and accuracy (AC) of upright ADCT (SE: 87.5 %, AC: 93.8 %) were significantly higher than those of supine ADCT (SE: 73.3 %, p &lt; 0.0001; AC: 86.7 %, p &lt; 0.0001).</div></div><div><h3>Conclusion</h3><div>Upright ADCT has better potential for the diagnosis and subtype classification of inguinal herniation than conventional supine ADCT when applied under the Valsalva maneuver.</div></div>","PeriodicalId":12063,"journal":{"name":"European Journal of Radiology","volume":"196 ","pages":"Article 112647"},"PeriodicalIF":3.3,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146074548","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development and validation of a radiomics model for lactate metabolism genes-based stratification and prognostic prediction in head and neck squamous cell carcinoma","authors":"Haotian Yuan ,&nbsp;Lin Yuan ,&nbsp;Jiapeng Chen ,&nbsp;Naixu Shi ,&nbsp;Detong Lin ,&nbsp;Xinyu Wang ,&nbsp;Chenfei Kong ,&nbsp;Xiaofeng Wang","doi":"10.1016/j.ejrad.2026.112666","DOIUrl":"10.1016/j.ejrad.2026.112666","url":null,"abstract":"<div><div>Head and neck squamous cell carcinoma (HNSCC) is a highly heterogeneous malignancy characterized by altered lactate metabolism, where traditional prognostic indicators are insufficient for precision medicine. This study aimed to construct an enhanced CT radiomics model integrated with lactate metabolism gene-related (LMGR) genomic signatures for HNSCC prognosis using TCGA and TCIA databases. A cohort of 399 HNSCC patients was analyzed. Analysis of 204 lactate-related genes identified 24 differentially expressed LMGR genes (DELMGR). Univariate Cox regression revealed that among these, PKLR, IL19, and CXCL9 exhibited protective effects (HR = 0.932, 0.885, and 0.931, respectively). A lactate classification score (LCS) was derived from the analysis of these three genes, demonstrating a significant correlation with overall survival (OS) in both univariate (HR = 1.807, 95 % CI: 1.346–2.424, P &lt; 0.001) and multivariate assessments (HR = 1.772, 95 % CI: 1.296–2.424, P &lt; 0.001). From enhanced CT images, 2060 radiomic features were extracted. Subsequently, after feature selection using mRMR and RFE algorithms, a support vector machine (SVM) model was built to predict LCS, which generated a radiomics score (RS). The model demonstrated AUC values of 0.773 and 0.760 in the training and validation datasets, respectively. The RS distribution significantly differed between lactate subtypes in the training cohort (P &lt; 0.001), with specifically higher RS in the high-risk LCS group. High RS was associated with poor OS (HR = 3.582, 95 % CI: 1.240–10.348, P = 0.018) and was correlated with clinical features such as the perineural invasion and the margin status. Mechanistic analysis indicated that the high RS group was enriched in an immunosuppressive microenvironment and was associated with fatty acid metabolism pathways. This enhanced CT-based radiomics model effectively predicts lactate-based stratification, demonstrating potential prognostic value in HNSCC and providing novel biomarkers as well as a non-invasive predictive tool for prognostic assessment.</div></div>","PeriodicalId":12063,"journal":{"name":"European Journal of Radiology","volume":"196 ","pages":"Article 112666"},"PeriodicalIF":3.3,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146035334","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Uterine artery embolization versus dienogest for symptomatic adenomyosis: A randomized controlled trial of short-term efficacy","authors":"Rania Refaat ,&nbsp;Eshraq Arabi Mohamed Ammar ,&nbsp;Mohammad Abd Alkhalik Basha ,&nbsp;Ahmed Mohamed Abouelhoda ,&nbsp;Pasant M. Abo-Elhoda ,&nbsp;Mohamed MohsenTolba Fawzi ,&nbsp;Abd EL-Aziz Galal EL-Dein EL-Darwish ,&nbsp;Khaled M. Abdallah ,&nbsp;Ahmed Abdelrady Ahmed","doi":"10.1016/j.ejrad.2026.112712","DOIUrl":"10.1016/j.ejrad.2026.112712","url":null,"abstract":"<div><h3>Rationale and objectives</h3><div>Adenomyosis significantly impairs quality of life, yet optimal uterine-sparing management remains uncertain. While both uterine artery embolization (UAE) and dienogest show promise, no direct comparison exists. This study compared their 6-month efficacy in treating symptomatic adenomyosis.</div></div><div><h3>Patients and methods</h3><div>This prospective, single-center, randomized controlled trial enrolled 60 patients with MRI-confirmed adenomyosis desiring uterine preservation between January and July 2025, randomly assigned (1:1) to UAE (n = 30) or 2 mg/day dienogest (n = 30). Co-primary outcomes were complete resolution of chronic pelvic pain and heavy menstrual bleeding at 6 months. Secondary outcomes included visual analog scale (VAS) dysmenorrhea scores, Uterine Fibroid Symptom and Quality of Life (UFS-QoL) symptom severity and health-related quality of life (HRQOL) scores, hemoglobin levels, junctional zone thickness, and uterine volume measured at baseline, 3 months, and 6 months.</div></div><div><h3>Results</h3><div>UAE achieved higher complete resolution rates for chronic pelvic pain (93.3% vs. 66.7%; p = 0.010; relative risk [RR] = 1.40) and heavy menstrual bleeding (90.0% vs. 56.7%; p = 0.004; RR = 1.59), with composite success in 86.7% versus 50.0% (RR = 1.73; number needed to treat = 3). At 6 months, UAE was associated with significantly better outcomes for VAS dysmenorrhea (1.27 ± 1.23 vs. 2.10 ± 1.25; p = 0.016), symptom severity scores (31.48 ± 9.78 vs. 45.36 ± 9.55; p &lt; 0.001), HRQOL scores (66.25 ± 7.35 vs. 50.82 ± 10.11; p &lt; 0.001), hemoglobin levels (10.55 ± 1.49 vs. 10.19 ± 1.55 g/dL; p = 0.010), junctional zone reduction (33.5% vs. 14.0%; p = 0.005), and uterine volume reduction (17.6% vs. 7.3%; p = 0.006).</div></div><div><h3>Conclusion</h3><div>At 6 months, UAE achieved better symptom relief and anatomical outcomes than dienogest, supporting UAE as an effective uterine-sparing therapy for symptomatic adenomyosis.</div></div>","PeriodicalId":12063,"journal":{"name":"European Journal of Radiology","volume":"196 ","pages":"Article 112712"},"PeriodicalIF":3.3,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146104495","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of two software programs for cross‐sectional body composition analysis on abdominal computed tomography scans of patients with cirrhosis","authors":"Francesca D’Arcangelo ,&nbsp;Alberto Zanetto ,&nbsp;Abha Dunichand-Hoedl ,&nbsp;Maryam Motamedrad ,&nbsp;Patrizia Burra ,&nbsp;Aldo J. Montano-Loza","doi":"10.1016/j.ejrad.2025.112637","DOIUrl":"10.1016/j.ejrad.2025.112637","url":null,"abstract":"<div><div>The impact of body composition abnormalities and clinical outcomes in patients with cirrhosis is well established. Abdominal computed tomography (CT) evaluation is the technique that is better evaluated; however, agreements are not well known. Fifty patients were randomly selected from two centers, and two observers independently evaluated their CT. The cross-sectional muscle area (CSMA), skeletal muscle index (SMI), muscle attenuation (MA), visceral adipose tissue area (VAT), visceral adipose tissue index (VATI), subcutaneous adipose tissue area (SAT), and subcutaneous adipose tissue area (SATI) were analyzed using SliceOmatic©V.5.0 (Magog, Canada), and Synapse 3D, Fujifilm. The interobserver and intersoftware intra-class correlation coefficients (ICCs) were highly equivalent for CSMA, SMI, MA, VAT, VATI, SAT, and SATI (Range 0.984–0.999, P &lt; 0.001), and excellent Pearson’s correlation coefficients were found for all comparisons (Range 0.970–0.998). Using different software programs to evaluate body composition in patients with cirrhosis showed excellent agreement for measuring muscle mass and adipose depots.</div></div>","PeriodicalId":12063,"journal":{"name":"European Journal of Radiology","volume":"196 ","pages":"Article 112637"},"PeriodicalIF":3.3,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145941147","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}