European Journal of Radiology最新文献

{"title":"Establishing updated diagnostic reference levels for interventional radiology: a national Italian survey incorporating procedure complexity indices – Part II: interventional neuroradiology","authors":"Monica Cavallari ,&nbsp;Loredana D’Ercole ,&nbsp;Sveva Grande ,&nbsp;Catherine Klersy ,&nbsp;Renato Padovani ,&nbsp;Antonio Orlacchio ,&nbsp;Gaetano Compagnone ,&nbsp;Antonella Rosi ,&nbsp;Alessandra Palma","doi":"10.1016/j.ejrad.2026.112662","DOIUrl":"10.1016/j.ejrad.2026.112662","url":null,"abstract":"<div><h3>Introduction</h3><div>To update the Italian Diagnostic Reference Levels (NDRLs) in interventional neuroradiology, the Istituto Superiore di Sanità coordinated a working group with consolidated expertise in this field. Establishing DRLs in interventional procedures is particularly challenging due to the complexity influenced by clinical and technical factors. For this reason, aim of this work is to provide DRLs that also take into account procedure complexity.</div></div><div><h3>Material and methods</h3><div>Data were collected from 20 Italian hospitals concerning cerebral angiography(CA), embolization of cerebral aneurysms (ECA), and Mechanical Thrombectomy (MT). For each procedure, Air-Kerma (K_a,r), Kerma-Area-Product(P_KA), and Fluoroscopy Time(FT) were recorded.</div><div>Data related to patient age, sex, and radiological equipment were registered. Additionally, for CA number of arteries evaluated, diagnostic priority (elective or emergency), and study type were documented. For ECA, aneurysm status, dome-to-neck ratio, aneurysm size, aneurysm location, and aneurysm morphology were recorded. For MT, collected data included occlusion type, thrombus location, and use of a stent retriever.</div></div><div><h3>Results</h3><div>P_KA distributions were analysed with non-parametric tests and generalized linear regression models to identify clinical and technical factors affecting dosimetry. Log transformations helped develop a complexity score to classify procedures. The new NDRLs are 191 Gy.cm² for CA (71 Gy.cm² for simple, 117 Gy.cm² for medium, 198 Gy.cm² for complex), 252 Gy.cm² for ECA (136 Gy.cm² for simple, 174 Gy.cm² medium, 268 Gy.cm² complex) and 169 Gy.cm² for MT (71 Gy.cm² for simple, 132 Gy.cm² for medium, 169 Gy.cm² for complex).</div></div><div><h3>Conclusion</h3><div>This study establishes updated national diagnostic reference levels for interventional neuroradiology in Italy through a comprehensive complexity-stratified approach. The research demonstrates the critical importance of regular DRL updates to reflect evolving practice patterns and technological advances, offering a more nuanced framework that recognizes the inherent variability of neuro interventional procedures across different complexity tiers.</div></div>","PeriodicalId":12063,"journal":{"name":"European Journal of Radiology","volume":"196 ","pages":"Article 112662"},"PeriodicalIF":3.3,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146009466","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Corrigendum to “RECIST progression: Patterns among target, non-target, non-measurable and new lesions progression” [Eur. J. Radiol. 186 (2025) 112038]","authors":"Teresa M. Tareco Bucho ,&nbsp;Luca Pascucci ,&nbsp;Giovanni Mancò ,&nbsp;Alessio Taraschi ,&nbsp;Maria Claudia Macchia ,&nbsp;Nicola Tinari ,&nbsp;Davide Brocco ,&nbsp;Regina G.H. Beets-Tan ,&nbsp;Andrea Delli Pizzi ,&nbsp;Stefano Trebeschi","doi":"10.1016/j.ejrad.2026.112708","DOIUrl":"10.1016/j.ejrad.2026.112708","url":null,"abstract":"","PeriodicalId":12063,"journal":{"name":"European Journal of Radiology","volume":"196 ","pages":"Article 112708"},"PeriodicalIF":3.3,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146137243","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of fish-hook shaped and spiral shaped wires in CT-guided pulmonary nodule localization: Impact on complications and clinical outcomes","authors":"Xiaowen Zhang ,&nbsp;Thom R.G. Stams ,&nbsp;Gonda J. de Jonge ,&nbsp;Marcel van Tuinen ,&nbsp;Caroline van de Wauwer ,&nbsp;Michiel Erasmus ,&nbsp;Mieke Zwager ,&nbsp;Geertruida H. de Bock ,&nbsp;Monique Dorrius","doi":"10.1016/j.ejrad.2026.112656","DOIUrl":"10.1016/j.ejrad.2026.112656","url":null,"abstract":"<div><h3>Objective</h3><div>In December 2020, our center transitioned from a fish-hook to a spiral wire for CT-guided pulmonary nodule localization. This study compared the effectiveness and safety of both techniques.</div></div><div><h3>Methods</h3><div>We retrospectively analyzed 154 consecutive patients with 157 pulmonary nodules who underwent CT-guided wire localization between November 2017 and December 2024. Demographic, lesion, procedural, surgical details, and pathology were collected. Technical success was defined as localization without wire dislodgement. Complications were categorized as minor (no intervention) or major (requiring intervention). Logistic regression identified risk factors for localization success and complications.</div></div><div><h3>Results</h3><div>Localization was performed using fish-hook wires in 79 and spiral wires in 78 procedures. Technical success rates were comparable (94.9 %, 95 %CI: 90.1 %-99.8 % vs. 94.9 %, 95 %CI: 90 %-99.8 %). Major complications were rare (two air embolisms and one drainage-requiring pneumothorax across all procedures). Minor complication rates were 34.2 % (95 % CI: 23.7 %–44.6 %) for fish-hook wires and 21.8 % (95 % CI: 12.6 %–31.0 %) for spiral wires. Pathological representativeness was similar. Wire type showed no difference in localization success (OR = 1.26, 95 % CI: 0.29–5.53). Fish-hook use (OR 2.36, 95 % CI 1.11–5.09) and longer procedure duration (OR 1.06, 95 % CI 1.02–1.10) were associated with minor complication risk.</div></div><div><h3>Conclusion</h3><div>Fish-hook and spiral shaped wires achieved comparable technical success and safety profile regarding major complications for CT-guided pulmonary nodule localization. However, from a patient perspective the relevance of minor complications should also be considered.</div></div>","PeriodicalId":12063,"journal":{"name":"European Journal of Radiology","volume":"196 ","pages":"Article 112656"},"PeriodicalIF":3.3,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145941148","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Transvaginal ultrasound for deep endometriosis: Prospective validation of SRU criteria and diagnostic value of indirect signs","authors":"Yixuan Hu ,&nbsp;Jinxia Wang ,&nbsp;Lingzhi Meng ,&nbsp;Jinzhen Song ,&nbsp;Zongli Yang","doi":"10.1016/j.ejrad.2026.112702","DOIUrl":"10.1016/j.ejrad.2026.112702","url":null,"abstract":"<div><h3>Background</h3><div>The SRU consensus on pelvic ultrasound proposed standardized augmented ultrasound, but its validity and indirect signs’ role require validation. This study will explore the application value of this consensus in deep endometriosis.</div></div><div><h3>Method</h3><div>This prospective study enrolled patients with clinically suspected endometriosis at Qingdao University Affiliated Hospital from May 2024 to April 2025. TVUS findings were compared with surgical findings. The diagnostic performance of TVUS for endometriosis was calculated, and multivariable logistic regression was applied to analyze associations between indirect sonographic signs and lesion locations.</div></div><div><h3>Results</h3><div>Included were 288 patients with clinical suspicion of DE. For DE detection, TVUS showed an overall accuracy of 84.4% (sensitivity 87.4%, specificity 76.8%). Fixed uterine retroflexion was significantly associated with bowel (OR 2.07, 95% CI 1.16–3.71), RVS (OR 2.83, 95% CI 1.34–6.32), and uterine serosal involvement (OR 2.38, 95% CI 1.19–4.88). Bowel tethering predicted bowel (OR 6.45, 95% CI 3.69–11.53), RVS (OR 4.53, 95% CI 2.24–9.62), uterine serosal (OR 2.15, 95% CI 1.12–4.18), and vaginal lesions (OR 3.83, 95% CI 1.85–8.25). Ipsilateral ovarian fixation or abnormal position was indicative of ipsilateral ovarian endometriosis (right: OR 16.9, 95% CI 9.15–32.96; left: OR 14.54, 95% CI 8.02–27.63) and USL involvement (right: OR 4.38, 95% CI 2.40–8.29, left: OR 2.23, 95%CI 1.3–3.91).</div></div><div><h3>Conclusion</h3><div>SRU-based ultrasound demonstrates high diagnostic accuracy for DE. Indirect signs effectively localize endometriotic lesions, enhancing surgical planning.</div></div>","PeriodicalId":12063,"journal":{"name":"European Journal of Radiology","volume":"196 ","pages":"Article 112702"},"PeriodicalIF":3.3,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146074524","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prognostic value of functional MRI and liver function synergy in hepatocellular carcinoma patients receiving combined locoregional-systemic therapy: A multicenter scoring model","authors":"Langlang Tang ,&nbsp;Kaiqian Que ,&nbsp;Yanfen Lan ,&nbsp;Yimin Li ,&nbsp;Bin Wang ,&nbsp;Zhuting Fang","doi":"10.1016/j.ejrad.2026.112705","DOIUrl":"10.1016/j.ejrad.2026.112705","url":null,"abstract":"<div><h3>Purpose</h3><div>To develop and validate a prognostic model integrating pretreatment MRI features and clinical characteristics for hepatocellular carcinoma (HCC) patients undergoing transarterial chemoembolization (TACE) and hepatic arterial infusion chemotherapy (HAIC) combined targeted immunotherapy (TII). A weighted scoring system was developed to improve the model’s clinical utility.</div></div><div><h3>Methods</h3><div>We retrospectively recruited 141 patients with HCC from multiple centers, with 98 in the training cohort and 43 in the validation cohort. The independent predictors were identified using univariate and multivariate Cox regression analyses and developed a clinical nomogram. We constructed an 10-point weighted scoring system incorporating imaging features. Model performance was evaluated using AUC, decision curve analysis (DCA), and calibration curves assessed via bootstrapping.</div></div><div><h3>Results</h3><div>Logistic regression identified four risk factors for objective response (OR): irregular tumor border, absent of Intratumoral artery, albumin-bilirubin (ALBI) score ≥ -2.352, number ≥ 2, and tumor histopathological enhancement (THPE). The AUC was 0.804 in the training cohort and 0.580 in the validation cohort. The Akaike Information Criterion (AIC) for the scoring model was lower than the other model for predicting OR, progression-free survival (PFS), and overall survival (OS). Patients with a scoring model value &gt; 5.5 points were classified as high-risk. The Kaplan-Meier (K-M) curves of the scoring model showed the better discriminative ability for PFS and OS.</div></div><div><h3>Conclusion</h3><div>The functional imaging-liver function synergy model demonstrates superior prognostic accuracy over conventional tumor burden parameters in hepatocellular carcinoma patients receiving quadruple therapy. Furthermore, the derived 10-point scoring system enables clinically actionable risk stratification.</div></div>","PeriodicalId":12063,"journal":{"name":"European Journal of Radiology","volume":"196 ","pages":"Article 112705"},"PeriodicalIF":3.3,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146074617","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Discriminating orbital lymphoma from inflammation and correlating with histopathology using microstructure-based time-dependent diffusion MRI","authors":"Hangzhi Liu ,&nbsp;Yingzhu Zhao ,&nbsp;Jing Li ,&nbsp;Xiaoxia Qu ,&nbsp;Tianying Ma ,&nbsp;Chen Zhang ,&nbsp;Thorsten Feiweier ,&nbsp;Xinyan Wang ,&nbsp;Junfang Xian","doi":"10.1016/j.ejrad.2026.112699","DOIUrl":"10.1016/j.ejrad.2026.112699","url":null,"abstract":"<div><h3>Background</h3><div>Preoperative discrimination between orbital B-cell lymphoma and inflammatory lesions remains a significant challenge using conventional imaging. This study evaluates the potential of time-dependent diffusion MRI (td-dMRI) alongside diffusion-weighted imaging (DWI) to improve differential diagnosis.</div></div><div><h3>Methods</h3><div>Patients with suspected orbital tumors were prospectively enrolled between October 2023 and November 2024. All participants underwent td-dMRI using oscillating gradient spin-echo (OGSE) and pulsed gradient spin-echo (PGSE) sequences on a 3 T scanner. Microstructural parameters—including cell diameter (d), cellularity, extracellular diffusivity (Dex), and intracellular volume fraction (Vin)—were derived. Correlations between apparent diffusion coefficient (ADC), d, cellularity, and histopathological metrics were assessed through quantitative morphometric analysis. Diagnostic performance was evaluated using receiver operating characteristic (ROC) analysis.</div></div><div><h3>Results</h3><div>Forty-eight patients were enrolled (20 orbital MALT lymphoma, 28 inflammatory lesions). All parameters showed excellent interobserver agreement (ICCs: 0.82–0.93). Strong correlations were observed between histological cell diameter and d (r = 0.75), and between histological cellularity and both td-dMRI-derived cellularity (r = 0.71) and ADC (r = -0.74) (all p &lt; 0.001). Lymphomas exhibited significantly lower ADC, d, and Dex, and higher Vin and cellularity compared to inflammatory lesions (all p &lt; 0.01). Cellularity demonstrated the highest discriminative power (AUC = 0.87), followed by Vin (AUC = 0.82), while ADC showed moderate performance (AUC = 0.74). No significant differences in diagnostic efficacy were observed among the parameters.</div></div><div><h3>Conclusions</h3><div>The td-dMRI provides highly reproducible, histologically correlated biomarkers that effectively differentiate orbital lymphoma from inflammatory lesions, thereby enabling orbital lesion risk-stratification and providing valuable non-invasive characterization to complement conventional ADC-based assessment for preoperative diagnosis of orbital lesions.</div></div>","PeriodicalId":12063,"journal":{"name":"European Journal of Radiology","volume":"196 ","pages":"Article 112699"},"PeriodicalIF":3.3,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146074549","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Benefits of photon counting CT for the assessment of native heart valves","authors":"Charles Mayard ,&nbsp;Salim Si-Mohamed ,&nbsp;Angèle Houmeau ,&nbsp;Cyril Prieur ,&nbsp;Jean-Nicolas Dacher ,&nbsp;Loic Boussel ,&nbsp;Philippe Douek ,&nbsp;Sara Boccalini","doi":"10.1016/j.ejrad.2026.112661","DOIUrl":"10.1016/j.ejrad.2026.112661","url":null,"abstract":"<div><h3>Objectives</h3><div>Systematic data about whether photon counting detector CT (PCD-CT) could improve the assessment of native heart valves is lacking. Thus, the aim of this study was to assess the performances of PCD-CT for the evaluation of native heart valves as compared to energy integrating detector CT (EID-CT).</div></div><div><h3>Methods</h3><div>Patients necessitating coronary artery CT were prospectively included (February 2021 to December 2022) to undergo an ECG-gated PCD-CT and EID-CT. A subjective assessment of the sharpness and conspicuity of each of the components of the four valves was performed with a 4-point scale. The number of small structures of the valvular apparati was calculated. The number of calcifications per leaflet and their localization within the thickness of the aortic leaflets were noted. The volume of the calcifications and the full width at mid weight (FWMH) of the aortic valve were calculated.</div></div><div><h3>Results</h3><div>Thirty-three patients (62 ± 13 years; 88 % men) were included. Conspicuity of aortic, mitral, and pulmonary valvular structures was increased with PCD-CT (all &lt; 0.05) except for the aortic right-non-coronary commissure and the pulmonary right-left commissure (p = 0.06 and p = 0.07). Sharpness was superior for all the borders and the commissures of the aortic and mitral valve (all p &lt; 0.05). More fine structures (nodules, chordae) and calcifications were visible with PCD-CT. The precise localization of the calcifications could be assessed with PCD-CT in most cases (70 %) while the volumes were similar (p = 0.07). FWMH was lower with PCD-CT (1.7(IQ = 1.1) vs 2.5 mm (IQ = 1.3); p &lt; 0.01).</div></div><div><h3>Conclusions</h3><div>PCD-CT yielded better subjective and objective image quality of native aortic, mitral and pulmonary valves and allowed for more structures to be detected compared to EID-CT. This might result in earlier, improved diagnosis of valve pathologies.</div></div>","PeriodicalId":12063,"journal":{"name":"European Journal of Radiology","volume":"196 ","pages":"Article 112661"},"PeriodicalIF":3.3,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146051150","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Silent magnetic resonance angiography: Techniques and applications of neurovascular imaging","authors":"Sunil Kumar,&nbsp;Smily Sharma,&nbsp;Vishnu Shivshankar Pujari,&nbsp;Venkata Subbaih Arunachalam,&nbsp;Bejoy Thomas,&nbsp;Santhosh Kumar Kannath,&nbsp;Jayadevan E.R.,&nbsp;Chandrasekharan Kesavadas","doi":"10.1016/j.ejrad.2026.112654","DOIUrl":"10.1016/j.ejrad.2026.112654","url":null,"abstract":"<div><h3>Purpose</h3><div>Silent Magnetic Resonance Angiography (S-MRA) is a non-contrast MR imaging method that utilises ultrashort echo in conjunction with the arterial spin labeling technique to produce angiographic images. The present article discusses the technical aspects of Silent MR angiography and its applications in neurovascular imaging, along with its advantages and pitfalls.</div></div><div><h3>Methods</h3><div>Using illustrative cases, various applications of the Silent MRA are explored along with a brief discussion on its technique and limitations. The Silent MR sequence provides an angiographic image with good background suppression in a duration of about 6–7 min and is devoid of saturation artefacts seen with Time of Flight (TOF) MR angiography.</div></div><div><h3>Results</h3><div>Applications include assessment of aneurysms (both untreated and treated cases), direct and indirect carotico-cavernous fistulas, dural arteriovenous fistulas, intracranial atherosclerotic disease, and Moya Moya disease with superior image quality compared to MR TOF angiography. It is particularly useful in post-procedural scans, such as after stenting and flow diverter placement, owing to reduced artefacts. In the pediatric population and acutely ill patients, an additional advantage includes reduced acoustic noise during the sequence, leading to diminished requirements for repeat studies.</div></div><div><h3>Conclusions</h3><div>S-MRA is a useful non-contrast MR angiography technique with improved image quality and reduced artifacts compared to MR TOF angiography, thereby facilitating the evaluation of multiple neurovascular diseases both pre- and post-interventions.</div></div>","PeriodicalId":12063,"journal":{"name":"European Journal of Radiology","volume":"196 ","pages":"Article 112654"},"PeriodicalIF":3.3,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145965721","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ultrasound dactylitis predicts bone erosion in early psoriatic arthritis: A longitudinal cohort study","authors":"Qian Zhang ,&nbsp;Cuilian Mao ,&nbsp;Fengyun Lu ,&nbsp;Yunjuan Wu ,&nbsp;Yao Ke ,&nbsp;Rui Liu","doi":"10.1016/j.ejrad.2026.112704","DOIUrl":"10.1016/j.ejrad.2026.112704","url":null,"abstract":"<div><h3>Objective</h3><div>Bone erosion is a hallmark of progressive joint damage and poor prognosis in psoriatic arthritis (PsA). Early identification of high-risk patients is critical for implementing aggressive interventions that can mitigate inflammation and prevent irreversible structural joint damage. This study aimed to identify clinical and ultrasonographic features associated with bone erosion in patients with early PsA.</div></div><div><h3>Methods</h3><div>A total of 82 patients with early PsA with articular and/or the entheseal involvement of less than 6-month duration were prospectively enrolled from the Rheumatology Department of the First Affiliated Hospital with Nanjing Medical University between March 2022 and January 2025 and followed for 24 months. Data about demographic and clinical characteristics, clinical enthesitis and dactylitis, and medication were collected. Musculoskeletal ultrasound was performed at baseline and the 2-year visit.<!--> <!-->Inflammatory and structural changes were scored with the modified MAdrid Sonographic Enthesitis Index (MASEI) and Novel and reliable DACTylitis glObal Sonographic (DACTOS) score. Erosions were defined by two radiology experts based on at least two imaging techniques. Logistic regression analysis was performed to identify variables associated with bone erosion occurring within 2 years of initial diagnosis. This trial has been registered on <span><span>ClinicalTrials.gov</span><svg><path></path></svg></span> under identifier NCT06730334.</div></div><div><h3>Results</h3><div>Early PsA patients with bone erosion had later onset of the disease (40.70 ± 13.35 vs 32.33 ± 13.98, p = 0.008), higher proportion with metabolic syndrome (p = 0.043), a greater number of swollen joints at baseline (p = 0.029), and higher DACTOS scores (p = 0.026). Over the 24-month follow-up, a higher proportion of patients without bone erosion received IL-17 inhibitor therapy (p = 0.034). Multivariate analysis identified older age at symptom onset (OR 1.049, p = 0.012) and higher DACTOS score (OR 1.082, p = 0.036) as independent predictors of bone erosion.</div></div><div><h3>Conclusion</h3><div>Our findings establish that an older age at symptom onset and a higher ultrasonographic dactylitis burden, quantified by the DACTOS score, are independent risk factors for bone erosion in early PsA. This supports the integration of ultrasound into early risk stratification to identify patients at greater risk for structural damage.</div></div>","PeriodicalId":12063,"journal":{"name":"European Journal of Radiology","volume":"196 ","pages":"Article 112704"},"PeriodicalIF":3.3,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146100086","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Predictive value of dynamic contrast enhanced magnetic resonance imaging and diffusion-weighted imaging in pancreatic cancer invasion and metastasis","authors":"Jun Fu ,&nbsp;Ji-Xin Li ,&nbsp;Ruzeaji Muhetaer ,&nbsp;Ze-Hong Yang ,&nbsp;Qi-Hua Yang","doi":"10.1016/j.ejrad.2026.112713","DOIUrl":"10.1016/j.ejrad.2026.112713","url":null,"abstract":"<div><h3>Objective</h3><div>To explore the clinical value of parameters of dynamic contrast enhanced magnetic resonance imaging (DCE-MRI) and diffusion-weighted imaging (DWI) in the diagnosis of pancreatic cancer and its invasiveness prediction.</div></div><div><h3>Materials and methods</h3><div>A total of 122 participants, comprising 58 patients with pathologically confirmed pancreatic cancer (median age 60.50 years [interquartile range, 54.00–65.25 years]; 38 males), 34 pancreatitis patients (median age 55.50 years[interquartile range, 43.00–67.25 years]; 23 males), and 30 healthy volunteers (median age 52.00 years[interquartile range, 36.00–62.25 years]; 16 males), underwent DWI and DCE-MRI scans. The values of K^trans (volume transfer constant), K_ep (rate constant), V_e (extravascular extracellular volume fraction), V_p (plasma volume fraction), TTP (Time to Peak), MAX Conc (Maximum Concentration), AUC (Area Under the Curve), and MAXSlope (Maximum Slope) from DCE sequence as well as the values of ADC and eADC from DWI sequence were collected. We also collected data on tumor invasion and metastasis within the pancreatic cancer cohort and divided it into ten subgroups. We analyzed the differences in parameters between pancreatic cancer, pancreatitis, and normal groups, and differences in parameters within pathologic subgroups of the pancreatic cancer group to distinguish among the groups. The area under the receiver operating characteristic curve (AUC) was used to assess diagnostic performance.</div></div><div><h3>Results</h3><div>The most prominent parameter to differentiate pancreatic cancer from pancreatitis was TTP, with AUC of 0.897, sensitivity of 86.2% and specificity of 91.2%. K^trans values were higher in the group with organ invasion than in the group without organ invasion (<em>p</em> = 0.007), higher in the group with nerve invasion than in the group without nerve invasion (<em>p</em> = 0.021), and lower in the group with implantation metastasis than in the group without implantation metastasis (<em>p</em> = 0.009) for pancreatic cancer.</div></div><div><h3>Conclusion</h3><div>DCE-MRI and DWI parameters were of clinical value in the diagnosis of pancreatic cancer. DCE parameters, especially K_trans, can be used to predict the occurrence of invasion or metastasis in pancreatic cancer.</div></div>","PeriodicalId":12063,"journal":{"name":"European Journal of Radiology","volume":"196 ","pages":"Article 112713"},"PeriodicalIF":3.3,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146104526","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}