European Journal of Psychiatry最新文献

{"title":"Late-Onset ADHD symptoms in the general population: A scoping review of longitudinal trajectories in population-based cohorts","authors":"Sophie Bayard ,&nbsp;Clarisse Madiouni ,&nbsp;François Radiguer ,&nbsp;Maëva Roulin ,&nbsp;Sébastien Henrard","doi":"10.1016/j.ejpsy.2025.100337","DOIUrl":"10.1016/j.ejpsy.2025.100337","url":null,"abstract":"<div><h3>Background and objectives</h3><div>The developmental validity of late-onset ADHD remains debated. This scoping review aimed to synthesize evidence from longitudinal trajectory studies in the general population to (1) examine the existence and characteristics of late-onset ADHD symptom trajectories, and (2) identify associated factors.</div></div><div><h3>Methods</h3><div>Following PRISMA-ScR guidelines, we systematically reviewed longitudinal studies published up to May 2025 that applied person-centered trajectory modeling to ADHD symptoms in population-based cohorts. Twelve eligible studies were included.</div></div><div><h3>Results</h3><div>Among the twelve studies included in this scoping review, ten identified at least one symptom trajectory consistent with late-onset ADHD, with prevalence estimates ranging from 3 % to 17.5 %, and were analyzed to examine associated factors. These late-onset trajectories were predominantly inattentive and less disruptive than persistent profiles, but consistently observed across cohorts but were reported in the majority of cohorts (10/12), not all. The most robustly supported associated factors included higher childhood cognitive functioning, fewer early externalizing problems, emerging internalizing psychopathology during adolescence, lower family socioeconomic status, female gender, and polygenic liability for ADHD. However, methodological variability, particularly in informant source, symptom measurement and model specification, significantly influenced identification. Notably, no study assessed sleep-wake disturbances, treatment history, contextual supports or neurological antecedents.</div></div><div><h3>Conclusion</h3><div>Late-onset ADHD trajectories are commonly identified in general population cohorts (10/12 studies). Their interpretation calls for a dimensional, developmentally sensitive framework. Future studies should incorporate overlooked domains such as sleep-wake functioning, treatment exposure, and neurological risk factors to refine clinical characterization and diagnostic criteria.</div></div>","PeriodicalId":12045,"journal":{"name":"European Journal of Psychiatry","volume":"40 1","pages":"Article 100337"},"PeriodicalIF":1.5,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145940124","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Use of benzodiazepines in primary care: prescriptions from 2010 to 2019 in Catalonia","authors":"Maria Antonieta Also Fontanet ,&nbsp;Sandra Murgui ,&nbsp;Elisenda Sant ,&nbsp;Mireia Sans-Corrales ,&nbsp;Antoni Sisó-Almirall ,&nbsp;Ariadna Mas ,&nbsp;Clàudia Valenzuela-Pascual ,&nbsp;Gerard Anmella ,&nbsp;Jordi Blanch ,&nbsp;Myriam Cavero ,&nbsp;Eduard Vieta ,&nbsp;Diego Hidalgo-Mazzei","doi":"10.1016/j.ejpsy.2026.100341","DOIUrl":"10.1016/j.ejpsy.2026.100341","url":null,"abstract":"<div><h3>Background and objectives</h3><div>Benzodiazepine (BZD) consumption has increased globally, with Spain among the highest-use countries. This study examines factors associated with intensive BZD in Catalonia’s primary care (PC) from 2010–2019.</div></div><div><h3>Methods</h3><div>Analyzed data from 713,196 adults attending PC without mental health service contact, excluding children, adolescents, and individuals with alcohol use disorders. Intensive BZD use was defined as &gt;56 Defined Daily Doses within an 8-week period. A hurdle model with a negative binomial distribution assessed factors influencing initiation and duration of intensive prescriptions. Multiple imputation addressed missing covariates.</div></div><div><h3>Results</h3><div>Of the study population, 67,184 adults (9.4%) received intensive BZD prescriptions in at least one year. Persistent users—those with prescriptions in all 10 follow-up years—numbered 6,767 and were predominantly female (81.6%) and Spanish nationals (99.2%). After adjustment, 54 of 92 associations (58.7%) remained significant. The strongest for sex, hypertension, and nationality:Females showed a 39% increase in the odds of heavy BZD use, while non-Spanish nationality was associated with a 45% reduction. Hypertension increased the odds by 57%, constituting comorbidity with the greatest impact on heavy use.Among persistent users, the most frequent diagnoses were anxiety (15.1%), insomnia (13.3%), and depression (8.5%).</div></div><div><h3>Conclusions</h3><div>Findings show initiation and persistence of intensive BZD use are influenced by different factors: initiation relates to sociodemographic characteristics, while persistence is driven by medical complexity. Women, Spanish nationals, and patients with hypertension are at highest risk of long-term use, underscoring the need for targeted interventions and deprescribing strategies.</div></div>","PeriodicalId":12045,"journal":{"name":"European Journal of Psychiatry","volume":"40 1","pages":"Article 100341"},"PeriodicalIF":1.5,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146034315","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Trauma and personality disorders in Danish treatment-seeking veterans","authors":"Ask Elklit ,&nbsp;Signe Fauerholdt Sørensen","doi":"10.1016/j.ejpsy.2025.100327","DOIUrl":"10.1016/j.ejpsy.2025.100327","url":null,"abstract":"<div><h3>Background &amp; objectives</h3><div>50.000 Danish soldiers have been deployed abroad during the last three decades. A recent study reported that 24 % were registered with either a psychiatric diagnosis or receiving psychotropic medication. We want 1) to explore the relationship between ICD-11 PTSD and complex PTSD (CPTSD), and severe personality pathology as well as clinical syndromes, and 2) to assess the mediating impact of social support, secondary trauma symptoms, and aggression for the two trauma diagnoses.</div></div><div><h3>Method</h3><div>142 male war veterans were assessed at intake to the outpatient services of a specialized trauma treatment facility. The participants completed an assessment battery. In addition to descriptive statistics, two multiple regression analyses were performed: one for PTSD and one for CPTSD.</div></div><div><h3>Results</h3><div>While less than half of the personality disorders and the clinical syndromes were associated with PTSD, almost all personality disorders and all the clinical syndromes were associated with CPTSD and to a much higher degree. 52 % of the variation of PTSD could be explained in the regression analysis with three significant factors in the final model: Anxiety, schizotypal personality disorder, and dissociation. In the similar analysis for CPTSD, 61 % of the variation was explained in the final model with Avoidant personality disorder and Negative Affectivity as significant factors. Social support and aggression were not significant predictors in either analysis.</div></div><div><h3>Conclusion</h3><div>The study supports the more severe sequelae associated with CPTSD compared to PTSD. The relationships between trauma disorders and personality pathology deserve more attention to inform the treatment of veterans.</div></div>","PeriodicalId":12045,"journal":{"name":"European Journal of Psychiatry","volume":"39 4","pages":"Article 100327"},"PeriodicalIF":1.5,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145265960","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Current state and future directions of biomarkers for bipolar disorder: A systematic review of studies from 2013 to 2025","authors":"Guocan Ma ,&nbsp;Fengyi Hao ,&nbsp;Soon-Kiat Chiang ,&nbsp;Dewen Zhou ,&nbsp;Roger C. Ho ,&nbsp;Roger S. McIntyre","doi":"10.1016/j.ejpsy.2025.100317","DOIUrl":"10.1016/j.ejpsy.2025.100317","url":null,"abstract":"<div><h3>Background and objectives</h3><div>Bipolar disorder (BD) is a severe mental disorder whose diagnosis heavily relies on subjective symptomatic assessments, thus a need for an objective tool to assist in the timely identification and treatment of BD.</div></div><div><h3>Methods</h3><div>We systematically reviewed the performance of objective diagnostic biomarkers for classification of BD that presented sensitivity and specificity values. A search on Ovid MEDLINE® ALL, PubMed, as well as manual searching were performed for literature dating from December 2013 to February 2025.</div></div><div><h3>Results</h3><div>Sixty-one studies were included in the review. Twenty-four of them reported mainly molecular, fluid-based biomarkers, twenty-five reported neurophysiological examinations as biomarkers, and six reported other forms of biomarkers. The most accurate biomarkers included voice features, apoptosis-related long non-coding RNAs, PIK3R1 (Phosphoinositide-3-kinase regulatory subunit 1) and FYN mRNAs, electroencephalography (EEG), functional near-infrared spectroscopy (fNIRS)<strong>,</strong> multimodal magnetic resonance imaging (MRI), and serum VGF protein, with area under the receiver operating characteristic curve (AUC) or accuracy values of greater than 0.93. The majority (thirty-six) of the studies utilized machine learning-based classification algorithms.</div></div><div><h3>Conclusions</h3><div>The results have been promising and replicated for some biomarkers, but these results still need to be validated in larger samples. Future studies should focus on constructing larger cohorts of specific clinical subtypes of BD, predictive utility studies for BD patients initially diagnosed as major depressive disorder (MDD), and utilization of multimodal assessment and machine learning techniques.</div></div>","PeriodicalId":12045,"journal":{"name":"European Journal of Psychiatry","volume":"39 4","pages":"Article 100317"},"PeriodicalIF":2.5,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144686224","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mental health law in Europe: Structures, standards, and ethical dilemmas a comparative analysis of 38 national frameworks in light of international guidelines, regarding involuntary measures in mental healthcare services","authors":"João Cortes Cardoso ,&nbsp;Cíntia Águas Pereira ,&nbsp;Silvana Galderisi ,&nbsp;Mariana Pinto da Costa ,&nbsp;Meryam Schouler-Ocak ,&nbsp;Thomas Pollmächer ,&nbsp;Luís Madeira","doi":"10.1016/j.ejpsy.2025.100326","DOIUrl":"10.1016/j.ejpsy.2025.100326","url":null,"abstract":"<div><h3>Background and Objectives</h3><div>In recent years, tensions have risen between the legislative context of Mental Health Laws (MHL) across Europe and the provisions set forth by the UN Convention on the Rights of Persons with Disabilities, pointing to ongoing discussions about autonomy and the conditions under which involuntary measures may occur.</div></div><div><h3>Methods</h3><div>A comparative analysis of national Mental Health Laws (MHL) across 44 European countries was conducted, focusing on legal frameworks for involuntary psychiatric care. It identifies 38 countries with MHL, excluding six without national legislation or where mental health is governed by regional frameworks. Data were collected from official sources and verified through the WHO Mental Health Atlas 2020. A total of 38 MHLs were analysed across four key domains: general definitions, formal procedures for involuntary admission, emergency procedures, and best practices in involuntary care.</div></div><div><h3>Results</h3><div>All MHLs require the presence of a mental disorder for involuntary admission, with 92 % also citing dangerousness. However, only 45 % provide a legal definition of mental disorder, and 29 % reference international diagnostic criteria (e.g., ICD, DSM). Procedures for involuntary admission are typically initiated by healthcare professionals (66 %), with courts serving as the primary deciding authority in 76 % of cases. Emergency detention durations vary, with many countries lacking clear limits. Best practices—such as distinguishing admission from treatment, allowing outpatient commitment, and requiring periodic legal review—are applied inconsistently. Only 14 countries explicitly prohibit controversial practices like psychosurgery or non-consensual ECT. While most laws emphasize protection of rights, the study highlights ethical tensions with the UN Convention on the Rights of Persons with Disabilities (CRPD), particularly around involuntary measures. Limitations include reliance on translated texts, the omission of subnational laws, and the lack of enforcement analysis.</div></div><div><h3>Conclusions</h3><div>These findings highlight the need for harmonized legal standards, enhanced procedural safeguards, and stronger rights-based frameworks in mental health legislation across Europe. Reforms should aim for standardized legal definitions, clearer procedures, and alignment with international norms, while remaining sensitive to clinical and cultural contexts.</div></div>","PeriodicalId":12045,"journal":{"name":"European Journal of Psychiatry","volume":"39 4","pages":"Article 100326"},"PeriodicalIF":1.5,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145324556","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The association of α-klotho/fibroblast growth factor 23 with cognitive features in euthymic older age patients with bipolar disorder","authors":"Wen-Yin Chen ,&nbsp;Chih Chiang Chiu ,&nbsp;Po-Hsiu Kuo ,&nbsp;Cho-Yin Huang ,&nbsp;Shang-Ying Tsia ,&nbsp;Chian-Jue Kuo ,&nbsp;Ying-Chih Cheng ,&nbsp;Po-Yu Chen ,&nbsp;Ming-Chyi Huang","doi":"10.1016/j.ejpsy.2025.100320","DOIUrl":"10.1016/j.ejpsy.2025.100320","url":null,"abstract":"<div><h3>Background and objectives</h3><div>Cognitive aging is common among bipolar disorder (BD). The α-klotho/fibroblast growth factor 23 (FGF23) system has been associated with neuropsychiatric disorders and age-related diseases. This study aimed to investigate α-klotho and FGF23 levels in older-age bipolar disorder (OABD) and examine their associations with aging-related characteristics and cognitive function.</div></div><div><h3>Methods</h3><div>This study included 87 euthymic OABD, 83 younger-age bipolar disorder (YABD), and 20 healthy controls, to assess α-klotho and FGF23 levels. In OABD group, cognitive function was evaluated using the Brief Assessment of Cognition in Affective Disorders. Aging-related features were assessed, including daily physical activity, grip strength, and the Framingham Risk Score. We examined the correlations between α-klotho/FGF23 levels and aging-related features and explored their associations with cognitive domains in OABD.</div></div><div><h3>Results</h3><div>The FGF23 levels in OABD were lower compared to those in YABD. The α-klotho levels were not significantly different between three groups. A negative association was observed between FGF23 and global cognitive composite scores (<em>B</em> = -0.006, <em>p</em> = 0.005), particularly in motor speed (<em>B</em> = -0.006, <em>p</em> = 0.001), working memory (<em>B</em> = -0.007, <em>p</em> = 0.006), and verbal fluency (<em>B</em> = -0.002, <em>p</em> = 0.049). Additionally, α-klotho levels were positively associated with working memory (<em>B</em> = 0.735, <em>p</em> = 0.039).</div></div><div><h3>Conclusions</h3><div>FGF23 had a negative impact on cognitive domains, while α-klotho was positively associated with working memory in OABD. Future research should investigate the dysfunction of the α-klotho/FGF23 axis and incorporate additional validated aging markers in longitudinal studies to confirm the proposed biomarker relationships.</div></div>","PeriodicalId":12045,"journal":{"name":"European Journal of Psychiatry","volume":"39 4","pages":"Article 100320"},"PeriodicalIF":1.5,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144886654","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Psychometric validation of the self-administered French version of the Functioning Assessment Short Test (FAST): Factor structure, reliability, validity, and sociodemographic predictors","authors":"Audrey Uyttersprot ,&nbsp;Nellia Bellaert ,&nbsp;Eduard Vieta ,&nbsp;Sandra Invernizzi ,&nbsp;Laurence Ris ,&nbsp;Laurent Lefebvre","doi":"10.1016/j.ejpsy.2025.100325","DOIUrl":"10.1016/j.ejpsy.2025.100325","url":null,"abstract":"<div><h3>Background and objectives</h3><div>The <em>Functioning Assessment Short Test</em> (FAST) is widely used to assess psychosocial functioning across psychiatric conditions. Despite extensive international validation, a validated French version of the self-administered FAST is currently lacking. This study aimed to evaluate the psychometric properties of the self-administered French FAST in a general adult population.</div></div><div><h3>Methods</h3><div>A total of 508 French-speaking adults aged 18–65 completed the FAST alongside standardized measures of depression and anxiety. Exploratory and confirmatory factor analyses and bifactor modeling evaluated the original six-factor structure. Reliability was assessed using Cronbach’s alpha and McDonald’s omega. Convergent validity was evaluated through multitrait-multimethod (MTMM) analysis and correlations with depression and anxiety. Generalized additive models (GAMs) examined non-linear associations between symptom severity and FAST scores, controlling for demographic covariates.</div></div><div><h3>Results</h3><div>The original six-factor structure was confirmed, and the bifactor model further supported interpretation of both total and subscale scores. Reliability was strong for the total FAST score (<em>α</em> = .86; <em>ω</em> = .90), whereas subscale reliability (<em>α</em> = .58–.80), with lower values for autonomy, cognitive, and leisure. MTMM analysis demonstrated moderate-to-high monotrait correlations (.51–.84), and moderate correlations with depressive (<em>r</em> = .46) and anxiety (<em>r</em> = .35) symptoms, supporting convergent validity. GAM analyses revealed a non-linear relationship between depressive symptoms and psychosocial impairment (<em>edf</em> = 2.91, <em>F</em> = 19.87, <em>p</em> &lt; .001), alongside significant effects of anxiety (<em>p</em> = .024) and employment status (<em>p</em> = .003).</div></div><div><h3>Conclusions</h3><div>The French self-administered FAST demonstrates robust psychometric properties and appears suitable for assessing psychosocial functioning in general adult populations, though caution is advised when interpreting autonomy, cognitive, and leisure subscales in non-clinical samples until further clinical validation is available.</div></div>","PeriodicalId":12045,"journal":{"name":"European Journal of Psychiatry","volume":"39 4","pages":"Article 100325"},"PeriodicalIF":1.5,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145154690","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical practice and metabolic consequences of olanzapine use in schizophrenia: results from a national survey in Spain","authors":"L.I. Muñoz-Manchado ,&nbsp;M. Bernardo ,&nbsp;J.M. Villagrán-Moreno ,&nbsp;E. Fernández-Egea","doi":"10.1016/j.ejpsy.2025.100323","DOIUrl":"10.1016/j.ejpsy.2025.100323","url":null,"abstract":"<div><h3>Background and objectives</h3><div>Schizophrenia is a psychiatric disorder with a global crude prevalence of approximately 23.6 million individuals and ranks among the top ten leading causes of disability worldwide. Antipsychotic medications, including olanzapine (Zyprexa), represent the most effective treatment option for these patients. This study aimed to assess the current prescribing patterns of olanzapine (Zyprexa).</div></div><div><h3>Methods</h3><div>To explore real-world prescribing patterns of olanzapine (Zyprexa), patient adherence, and the perceived incidence of adverse effects—especially metabolic syndrome—a structured, purpose-designed survey was distributed to psychiatrists across Spain.</div></div><div><h3>Results</h3><div>A total of 197 Consultant psychiatrists practising in Spain responded to a survey on olanzapine (Zyprexa) use patterns. olanzapine (Zyprexa) was noted for its high efficacy, rapid onset of action, and tolerability. The majority of psychiatrists (77.8 %) reported prescribing olanzapine (Zyprexa) primarily to patients aged 31–50 years. Regarding metabolic syndrome, out of 111 responses, 60.4 % (66 psychiatrists) considered olanzapine (Zyprexa) to be associated with a higher incidence of metabolic syndrome, which was reported to occur predominantly at an early stage (61.3 %).</div></div><div><h3>Conclusions</h3><div>Treatment adherence to olanzapine (Zyprexa) may be negatively affected by adverse events such as weight gain and the development of metabolic syndrome, which could serve as causal factors for treatment discontinuation. The implementation of both pharmacological and non-pharmacological strategies aimed at metabolic control may play a key role in optimizing the therapeutic management of schizophrenia.</div></div>","PeriodicalId":12045,"journal":{"name":"European Journal of Psychiatry","volume":"39 4","pages":"Article 100323"},"PeriodicalIF":1.5,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145358594","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Telehealth group parent training for children with autism spectrum disorder and behavioral difficulties: feasibility, acceptability and preliminary efficacy","authors":"Imanol Setien-Ramos ,&nbsp;Teresa Alonzo-Castillo ,&nbsp;Aina García-Martínez ,&nbsp;Jorge Lugo-Marín ,&nbsp;María Martínez-Ramírez ,&nbsp;Josep Antoni Ramos-Quiroga ,&nbsp;Laura Gisbert-Gustemps","doi":"10.1016/j.ejpsy.2025.100319","DOIUrl":"10.1016/j.ejpsy.2025.100319","url":null,"abstract":"<div><h3>Background and objectives</h3><div>Children with Autism Spectrum Disorder (ASD) frequently experience significant behavioral challenges that hinder adaptive functioning and increase caregiver stress. This study assesses the feasibility, acceptability, and preliminary efficacy of a telehealth-delivered group parent training program designed to address behavioral difficulties in children with ASD.</div></div><div><h3>Method</h3><div>An open-label, single-arm trial was conducted with children aged 3–12 years diagnosed with ASD and behavioral difficulties, recruited from a tertiary hospital’s autism care program. Program effectiveness was evaluated using parent-reported measures on their children and on themselves assessing behavior problems, parental stress, and quality of life. Data analysis included pre-post comparisons and follow-up assessments at 3 and 6 months.</div></div><div><h3>Results</h3><div>Twenty dyads parent-children were analyzed. Satisfaction with the program was moderate, with especially favorable feedback on the \"planned ignoring\" unit. Preferences for delivery mode and format varied, with suggestions to reduce the number of tasks and tailor content to individual needs. Significant reductions in irritability, lethargy, hyperactivity were observed immediately after treatment, with improvements in irritability and hyperactivity sustained at the 3- and 6-month follow-ups. Parental stress decreased significantly post-treatment but did not persist over time. Quality of life improved significantly compared to baseline, both immediately post-treatment and during follow-up evaluations.</div></div><div><h3>Conclusions</h3><div>The telehealth-delivered group parent training program demonstrated feasibility and moderate acceptability, with significant improvements in child behavior and caregiver quality of life. However, the reduction in parental stress was not sustained over time. These findings underscore the potential of telehealth-delivered group interventions for managing ASD-related behavioral issues and indicate areas for program refinement to enhance adherence and long-term effectiveness.</div></div>","PeriodicalId":12045,"journal":{"name":"European Journal of Psychiatry","volume":"39 4","pages":"Article 100319"},"PeriodicalIF":1.5,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144886724","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Measuring referentiality in psychiatric disorders: Psychometric properties of the Spanish version of the Ideas of Reference and Interview Scale (IRIS-S)","authors":"Isabel Argila-Plaza ,&nbsp;Ana Aquino-Servín ,&nbsp;María Ángeles García-León ,&nbsp;Paola Fuentes-Claramonte ,&nbsp;Núria Ramiro ,&nbsp;Pilar Salgado-Pineda ,&nbsp;Joan Soler-Vidal ,&nbsp;María Llanos Torres ,&nbsp;Amalia Guerrero-Pedraza ,&nbsp;Manel Sánchez ,&nbsp;Salvador Sarró ,&nbsp;Raymond Salvador ,&nbsp;Peter J McKenna ,&nbsp;Ana Barajas ,&nbsp;Edith Pomarol-Clotet","doi":"10.1016/j.ejpsy.2025.100329","DOIUrl":"10.1016/j.ejpsy.2025.100329","url":null,"abstract":"<div><h3>Background and objectives</h3><div>Referentiality is a common symptom in psychotic and also some non-psychotic disorders, but there are few existing measures for assessing it. A recently developed detailed measure for this purpose is the Ideas of Reference Interview Scale (IRIS), which however has only been validated in a Chinese population of first episode psychosis patients.</div></div><div><h3>Methods</h3><div>We examined the reliability and validity of a Spanish version of the IRIS (IRIS-S) in 185 patients aged between 18 and 65 with schizophrenia or schizoaffective disorder.</div></div><div><h3>Results</h3><div>The IRIS-S showed internal consistency, with this being good or acceptable for the presence scale and its three subsidiary measures. Inter-rater reliability was good and test-retest reliability was also good, except for one subsidiary measure. Convergent reliability was demonstrated but was lower than expected.</div></div><div><h3>Conclusion</h3><div>The IRIS-S has acceptable psychometric properties when employed in patients with schizophrenia/schizoaffective disorder. Caution is necessary for its use outside psychotic disorders as it has not been examined in such populations.</div></div>","PeriodicalId":12045,"journal":{"name":"European Journal of Psychiatry","volume":"39 4","pages":"Article 100329"},"PeriodicalIF":1.5,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145358593","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}