European Journal of Psychiatry最新文献

{"title":"Identification of a linoleic acid derivative in elderly female patients with schizophrenia from rural regions using untargeted metabolomics","authors":"Bo Pan ,&nbsp;Li Qu ,&nbsp;Chuan-Lan Wang ,&nbsp;Jianjun Weng ,&nbsp;Jian-Feng Yu ,&nbsp;Yanqing Liu ,&nbsp;Xing-Chen Wang","doi":"10.1016/j.ejpsy.2024.100285","DOIUrl":"10.1016/j.ejpsy.2024.100285","url":null,"abstract":"<div><h3>Background and objectives</h3><div>Schizophrenia is a chronic and severe mental illness, affecting a large number of general populations. It was well documented that metabolic dysregulation is associated with schizophrenia. In order to define reliable peripheral biomarkers for schizophrenia in patients with specific age, sex, and locations, plasma metabolic profiling of elderly female schizophrenic patients in rural regions was investigated in this study.</div></div><div><h3>Methods</h3><div>A total of 20 female schizophrenic patients (average age: 68.65 ± 4.11) and 20 matched healthy controls were recruited. An untargeted metabolomics analysis was performed with their plasma samples of the participants. Differentially-expressed metabolites (DEMs) were identified, followed by a pathway enrichment analysis to reveal related signalling pathways. Then, machine learning analyses, including random forest (RF) and support vector machines-recursive feature elimination (SVM-RFE), were implemented to determine signature metabolite(s).</div></div><div><h3>Results</h3><div>A total number of 2764 metabolites were identified, among which 61 DEMs were identified, including 38 down-regulated and 23 up-regulated metabolites. The enrichment analysis showed that glycerophospholipid metabolism and sphingolipid signalling pathway were the most significantly affected pathways. The ROC analysis indicated that metabolites belonging to the class of fatty acyls have higher power to discriminate schizophrenia. Finally, a linoleic acid derivative (Dg(16:0/18:2(9z,12z)/0:0)[Iso2]) was revealed as signature metabolite by the RF and SVM-RFE machine learning analyses.</div></div><div><h3>Conclusion</h3><div>The present study investigated the plasma metabolic profiling of elderly female patients with schizophrenia and identified a peripheral linoleic acid derivative that might help discriminate schizophrenia and develop specific treatment strategies for elderly female patients in rural regions.</div></div>","PeriodicalId":12045,"journal":{"name":"European Journal of Psychiatry","volume":"39 2","pages":"Article 100285"},"PeriodicalIF":2.5,"publicationDate":"2024-12-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143172287","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Validation study for the individual recovery outcomes counter (I.ROC) in a Spanish population.","authors":"José A. Garrido-Cervera ,&nbsp;María I. Ruiz-Granados ,&nbsp;Antonio I. Cuesta-Vargas ,&nbsp;Antonio J. Sánchez-Guarnido","doi":"10.1016/j.ejpsy.2024.100287","DOIUrl":"10.1016/j.ejpsy.2024.100287","url":null,"abstract":"<div><h3>Background and Objective</h3><div>To improve mental health recovery, it is necessary to have validated instruments. At present, however, there is a lack of valid instruments capable of measuring the recovery process in Spanish-speaking populations. The objective of this study was therefore to translate, culturally adapt and validate the Individual Recovery Outcomes Counter (I.ROC) for use in Spanish populations.</div></div><div><h3>Methods</h3><div>The methodology applied was that recommended for cultural adaptations of questionnaires. It included the following phases: translation, back translation, cultural adaptation and understandability analysis. To assess its psychometric properties, the translated version of the I.ROC was administered to 307 people with severe mental disorders (SMDs).</div></div><div><h3>Results</h3><div>The questionnaire's internal consistency was satisfactory (Cronbach's alpha = 0.894). Its stability over time was also appropriate, with no significant differences being found in any of the items in the two evaluations. Concurrent validity with the Recovery Assessment Scale (RAS-24) was also acceptable (<em>r</em> = 0.663 <em>p</em> &lt; 0.001). The exploratory factor analysis (EFA) results were concordant with a division into the 4 original factors, but also compatible with two or even with one single general factor.</div></div><div><h3>Conclusion</h3><div>The results of the study suggest that the Spanish version of the I.ROC is a valid, reliable instrument for charting recovery in people with mental disorders (MD).</div></div>","PeriodicalId":12045,"journal":{"name":"European Journal of Psychiatry","volume":"39 2","pages":"Article 100287"},"PeriodicalIF":2.5,"publicationDate":"2024-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143172736","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The role of communication and social support in suicidal behaviour in adults aged between 18–40 years: A systematic review","authors":"Noelia Lucía Martínez-Rives ,&nbsp;María Pilar Martín Chaparro ,&nbsp;Yasuhiro Kotera ,&nbsp;Bibha Dhungel ,&nbsp;Stuart Gilmour","doi":"10.1016/j.ejpsy.2024.100266","DOIUrl":"10.1016/j.ejpsy.2024.100266","url":null,"abstract":"<div><h3>Background and objectives</h3><div>Social support and quality communication are crucial in suicide prevention. This systematic review aimed to identify and summarize the research on the link between these variables and suicidal behavior in adults, and their differences depending on gender.</div></div><div><h3>Methods</h3><div>The Web of Science, Scopus and PsycInfo databases were searched from January 2012 to November 2022 using the terms [(suicide* OR “deliberate self-harm”* OR self- injur* OR “suicidal behavio”*) AND (\"social support\" OR \"interpersonal relationship\") AND (communication)]. Articles published in a peer-reviewed academic journal, written in English, with participants between 18 and 40 years old, assessing communication and/or social support were included.</div></div><div><h3>Results</h3><div>Finally, we included 12 articles. We identified characteristics such as not perceiving social networks as a helpful resource, or difficulties in understanding the messages. Also, the COVID-19 pandemic, highlighted the role that technology played in social support for the most vulnerable people. Communication difficulties of the individual with greater risk for suicide, showed the importance of social support and seeking help.</div></div><div><h3>Conclusions</h3><div>The community can contribute in suicide prevention by reducing the stigma surrounding mental illness and suicide through effective communication.</div></div>","PeriodicalId":12045,"journal":{"name":"European Journal of Psychiatry","volume":"39 1","pages":"Article 100266"},"PeriodicalIF":2.5,"publicationDate":"2024-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142702327","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Influence of 5-HTT, COMT, and BDNF functional polymorphisms and their interaction with parental bonding in attachment anxiety, among adults with personality disorders","authors":"Leire Erkoreka ,&nbsp;Iker Zamalloa ,&nbsp;Pedro Muñoz ,&nbsp;Santiago Rodriguez ,&nbsp;Aurora Arrue ,&nbsp;Miguel Angel Gonzalez-Torres","doi":"10.1016/j.ejpsy.2024.100270","DOIUrl":"10.1016/j.ejpsy.2024.100270","url":null,"abstract":"<div><h3>Background and objectives</h3><div>Attachment is the tendency of human beings to create strong affective bonds towards specific figures, and has been described as a general vulnerability factor to diverse forms of psychopathology. Although attachment research has not tended to emphasize genetic contribution, heritability is estimated at 36–45 %. We explored the association between <em>5-HTTLPR, COMT</em> Val158Met and <em>BDNF</em> Val66Met functional polymorphisms with attachment dimensions, as well as the gene-environment interaction, considering the perceived parental rearing styles, with both a vulnerability and a differential susceptibility approach.</div></div><div><h3>Methods</h3><div>150 outpatients with a cluster B personality disorder participated in the study. Attachment was assessed using Experiences in Close Relationships-Revised and rearing styles by means of the Parental Bonding Instrument. Genotypes were analyzed using saliva samples. Statistical analyses were carried out with general linear models.</div></div><div><h3>Results</h3><div><em>COMT</em> ValVal homozygotes and <em>BDNF</em> Met-carriers were associated with significantly higher scores in attachment anxiety (COMT: ValVal 4.95±1.25 vs Met-carriers 4.42±1.30, <em>t</em>=-2.096, <em>p</em>=0.038; BDNF: ValVal 4.38±1.31 vs Met-carriers 4.95±1.24, <em>t</em> = 2.833, <em>p</em>=0.005). From a differential susceptibility approach, plasticity genotypes were identified for the three functional polymorphisms, observing significant interactions with parental overprotection and differential outcomes in relation to attachment anxiety. No associations or interactions were found with regard to attachment avoidance and the care dimension.</div></div><div><h3>Conclusion</h3><div>Our results suggest that there are individuals more susceptible to rearing experiences in terms of adult attachment outcomes, which probably also implies a greater potential to benefit from environmental and psychotherapeutic interventions.</div></div>","PeriodicalId":12045,"journal":{"name":"European Journal of Psychiatry","volume":"39 1","pages":"Article 100270"},"PeriodicalIF":2.5,"publicationDate":"2024-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142701756","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A collective case study of mental health systems’ response to COVID-19: Impact on patterns of care provision for depression and anxiety in two comparable regions of Southern Europe","authors":"G Castelpietra ,&nbsp;T Niyonsenga ,&nbsp;A Iruin ,&nbsp;U Albert ,&nbsp;A Gabilondo ,&nbsp;L Salvador-Carulla","doi":"10.1016/j.ejpsy.2024.100278","DOIUrl":"10.1016/j.ejpsy.2024.100278","url":null,"abstract":"<div><h3>Background and Objectives</h3><div>COVID-19 pandemic has affected the mental health system (MHS) globally, although significant geographical variation was found, particularly for depression and anxiety. The understanding of its impact at the regional level of the context of care is limited when compared to national evaluations.</div></div><div><h3>Methods</h3><div>Collective case study comparing the prior pattern of care with the first 11 months of COVID-19 in two sites: Gipuzkoa (Spain) and Friuli Venezia Giulia - FVG (Italy). Information from both sites derive from administrative data of MHS in the two regions harmonized for comparison. Data included prevalence of psychiatric diagnoses (ICD-10 F30-F39 and F40-F49 codes), number of hospitalisations, mean and range of psychiatric and psychological interventions. Significance of time-period and location difference was assessed using the Chi-square and the T-statistics for prevalence and count data, respectively.</div></div><div><h3>Results</h3><div>MHS is community-based in both sites. The prevalence of anxiety decreased in FVG, while a decrease in hospitalisations was found in Gipuzkoa. Both sites registered an increase in psychiatric visits for anxiety and depression. In both periods, FVG showed significant lower prevalence of diagnoses, but higher mean number of psychiatric interventions.</div></div><div><h3>Conclusions</h3><div><strong>:</strong> The COVID-19 outbreak is a paradigmatic example of complex dynamic systems in public health and illustrates the importance of considering its local context and time dependency. The Standard mapping and coding of local MHS provision is essential to allow comparison and reduce ambiguity. This study highlights the importance of ecosystem research to better interpret epidemiological data and support the development of evidence-informed policymaking.</div></div>","PeriodicalId":12045,"journal":{"name":"European Journal of Psychiatry","volume":"39 1","pages":"Article 100278"},"PeriodicalIF":2.5,"publicationDate":"2024-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142701758","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Has psychiatric emergency care changed after the COVID-19 pandemic? A retrospective study in a tertiary hospital in Madrid, Spain","authors":"Carolina Fajardo ,&nbsp;Simona Sciacchitano ,&nbsp;Alba Maria Pozo-Prados ,&nbsp;Ana Izquierdo ,&nbsp;Álvaro Orosa-Duarte ,&nbsp;Eduardo Delgado-Parada ,&nbsp;Jose Luis Ayuso-Mateos ,&nbsp;Iosune Torio","doi":"10.1016/j.ejpsy.2024.100281","DOIUrl":"10.1016/j.ejpsy.2024.100281","url":null,"abstract":"<div><h3>Background and objectives</h3><div>The COVID-19 pandemic and the ensuing restrictive measures had a detrimental impact on the mental health of the population, potentially altering the pattern of seeking psychiatric care. A retrospective cross-sectional study was conducted to compare Psychiatric Emergencies after the most restrictive phases of the pandemic with an equivalent pre-pandemic period. Additionally, we aimed to investigate a possible association between the influx of patients to the emergency department (ED) and the cumulative incidence of COVID-19 cases.</div></div><div><h3>Methods</h3><div>Data from the psychiatric ED of a tertiary hospital in Madrid, Spain, during the so-called “new normal” phase (October 2020 - May 2021) were compared with a corresponding period (October 2018 - May 2019).</div></div><div><h3>Results</h3><div>The number of visits to the ED significantly increased from 879 to 980 after the pandemic. Patients were more likely to be compulsorily transferred (<em>M</em> = 281, SD 28.7 vs. <em>M</em> = 209, SD 23.8) and had a higher likelihood of requiring psychiatric hospitalization (<em>M</em> = 323, SD 33.0 vs. <em>M</em> = 246, SD 28.0). Notably, the number of visits related to suicide attempts was significantly higher during the pandemic (<em>M</em> = 147, SD 15.0 vs. <em>M</em> = 86, SD 9.8), while the proportion of patients with bipolar disorder decreased (<em>M</em> = 89, SD 9.1 vs. <em>M</em> = 121, SD 13.8). No significant results were found regarding a possible association between the number of patients in the ED and the COVID-19 incidence rate.</div></div><div><h3>Conclusions</h3><div>These results suggest critical changes in psychiatric emergency care and an increasing trend of suicide attempts during the pandemic, emphasizing the need for the reorganization of emergency care in future health crises.</div></div>","PeriodicalId":12045,"journal":{"name":"European Journal of Psychiatry","volume":"39 1","pages":"Article 100281"},"PeriodicalIF":2.5,"publicationDate":"2024-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142701759","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Testing implementation support strategies to facilitate an evidence-based substance use and mental health care intervention in veterans treatment courts: A hybrid type III trial protocol","authors":"David A. Smelson ,&nbsp;Vera Yakovchenko ,&nbsp;Kathryn E. Bruzios ,&nbsp;Thomas Byrne ,&nbsp;Megan Mccullough ,&nbsp;Paige M. Shaffer ,&nbsp;A. Rani Elwy","doi":"10.1016/j.ejpsy.2024.100282","DOIUrl":"10.1016/j.ejpsy.2024.100282","url":null,"abstract":"<div><h3>Background and Objectives</h3><div>Veterans Treatment Courts (VTCs) are alternative to incarceration programs for veterans involved in the criminal legal system. VTC participants have high rates of co-occurring mental health and substance use disorders (COD). Maintaining Independence and Sobriety Through Systems Integration, Outreach and Networking – Criminal Justice (MISSION<img>CJ) is an evidence-based, multicomponent intervention offered alongside VTCs to support veterans’ complex needs. Multicomponent interventions are often difficult to implement nationally, let alone when care is offered and coordinated across multiple systems. This protocol offers an overview of an implementation-effectiveness trial of MISSION<img>CJ in VTCs.</div></div><div><h3>Methods</h3><div>This quality improvement (QI) project will involve an adaptive, randomized design, in which VA staff in four geographically-dispersed regions across the U.S. will be invited to participate and receive varying implementation facilitation (IF) support (i.e., low/passive and high/active) for implementing MISSION<img>CJ. Sites will have a 9-month run-in period (e.g., orientation) followed by 9-months of low/passive IF. Sites that meet an implementation benchmark will then be randomized to continue low/passive IF or discontinue; and sites that do not meet the benchmark will be randomized to continue low/passive IF, or receive high/active IF for 12-months. Implementation outcomes are based on the RE-AIM (Reach, Effectiveness, Adoption, Implementation, Maintenance) framework (e.g., reaching eligible veterans, adoption rates, fidelity to MISSION<img>CJ, and maintenance/sustainment). MISSION<img>CJ effectiveness outcomes include treatment engagement and COD improvements.</div></div><div><h3>Discussion</h3><div>This QI project aims to determine the most effective type and intensity of IF to increase MISSION<img>CJ, while improving outcomes among VTC participants. As the first national trial to implement MISSION<img>CJ in VTCs, it has important implications for the criminal legal and implementation science fields.</div></div><div><h3>Trial Registration</h3><div>ISRCTN registry, ISRCTN13576289, Registered 21 December 2022, https://www.isrctn.com/ISRCTN13576289</div></div>","PeriodicalId":12045,"journal":{"name":"European Journal of Psychiatry","volume":"39 1","pages":"Article 100282"},"PeriodicalIF":2.5,"publicationDate":"2024-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142701768","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Systematic review of psychological assessment tools in emergencies, crises, and disasters","authors":"Alba Pérez-González ,&nbsp;Adolfo Jarne","doi":"10.1016/j.ejpsy.2024.100271","DOIUrl":"10.1016/j.ejpsy.2024.100271","url":null,"abstract":"<div><h3>Objectives</h3><div>We conducted a systematic review to determine which psychological assessment measures are most commonly used by emergency services to assess the psychological response of the general population in a crisis event and the time point at which the assessment is carried out.</div></div><div><h3>Method</h3><div>A systematic review was performed based on PRISMA recommendations and registered with PROSPERO by searching in electronic citation databases (Web of Science, PubMed, and PsycInfo).</div></div><div><h3>Results</h3><div>Twelve studies were included. The flowchart shows the entire decision-making process. Among the variables assessed, self-report measures that assess PTSD stand out above all others, followed by self-report measures that assess negative emotional states (anxiety and depression). Psychologists frequently appeared among the professionals involved in the assessments. None of the experiences analyzed were an assessment carried out immediately after the event.</div></div><div><h3>Conclusion</h3><div>Very few psychological assessment instruments have been developed in the context of emergencies, and those that are used are translations of others designed in a clinical context. According to the latest research, studies tend to overlook the importance of the time elapsed between the event and assessment.</div></div>","PeriodicalId":12045,"journal":{"name":"European Journal of Psychiatry","volume":"39 1","pages":"Article 100271"},"PeriodicalIF":2.5,"publicationDate":"2024-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142701766","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Problematic gaming use and psychological distress among Spanish young adults: A comprehensive study","authors":"E. Suárez-Soto ,&nbsp;A. Peris-de la Hoz ,&nbsp;A. Sanchez-Fernandez-Quejo ,&nbsp;E. Rodriguez-Toscano ,&nbsp;N. Lagunas ,&nbsp;B. Reneses ,&nbsp;A. De la Torre-Luque","doi":"10.1016/j.ejpsy.2024.100279","DOIUrl":"10.1016/j.ejpsy.2024.100279","url":null,"abstract":"<div><h3>Background and objectives</h3><div>This study examined problematic video game use and its sociodemographic and clinical correlates in a sample of 1,410 Spanish video game players (33.6% women; mean age = 21.12 years, SD = 3.29).</div></div><div><h3>Methods</h3><div>The participants completed a comprehensive set of assessment scales to evaluate clinical features: a sociodemographic interview, problematic video gaming (using the GAS-7), emotional symptoms (with the Goldberg Anxiety and Depression scales), suicidal ideation (with the Paykel Suicidal Ideation Scale), loneliness (De Jong Gierveld Loneliness Scale) and impulsivity (UPPS-P scale). Participants were classified based on problematic gaming severity. Differences between groups were explored for the clinical features assessed.</div></div><div><h3>Results</h3><div>As a result, most participants showed a low-risk gaming pattern (88.2%), in comparison to those showing either excessive use of video games (10% of participants) or problematic (pathological) gaming use (almost 2%). Risk groups differed by sex (<em>p</em> &lt; .01), but not age, education, or employment. Game time and frequency varied across risk groups, indicating higher use with greater risk. Clinical correlates were examined, with higher risk groups showing more depressive symptoms (<em>p</em> &lt; .01), anxiety symptoms (<em>p</em> &lt; .01), suicidal ideation (<em>p</em> &lt; .01), and loneliness (<em>p</em> &lt; .01). Impulsiveness dimensions also showed significant group differences, except for sensation seeking. In conclusion, problematic video game use was linked to higher levels of depressive symptoms, anxiety, suicidal ideation, loneliness, and impulsiveness.</div></div><div><h3>Conclusion</h3><div>This study sheds light on the clinical aspects associated with different levels of problematic gaming.</div></div>","PeriodicalId":12045,"journal":{"name":"European Journal of Psychiatry","volume":"39 1","pages":"Article 100279"},"PeriodicalIF":2.5,"publicationDate":"2024-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142701757","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dissociation and dysfunctional personality traits in patients with borderline personality disorder: A study based On DSM-5 alternative model","authors":"Margherita Alfieri ,&nbsp;Anna Caterina Leucci ,&nbsp;Biancamaria Bortolotti ,&nbsp;Sara Gibiino ,&nbsp;Loredana Lia ,&nbsp;Lorenzo Pelizza ,&nbsp;Marco Menchetti","doi":"10.1016/j.ejpsy.2024.100283","DOIUrl":"10.1016/j.ejpsy.2024.100283","url":null,"abstract":"<div><h3>Background and objectives</h3><div>Borderline Personality Disorder (BPD) and dissociative experiences are frequently co-occurring conditions. This study aimed to assess the relationship between DSM-5 Alternative Model of Personality Disorder (AMPD) maladaptive personality facets and self-report dissociation in a sample of patients with BPD.</div></div><div><h3>Methods</h3><div>Our sample consisted of 178 Italian adult patients who met the criteria for BPD diagnosed by Structured Clinical Interview for DSM IV-Axis II. They were administered the Personality Inventory for DSM-5 (PID-5) and the Dissociative Experiences Scale (DES). An agglomerative hierarchical cluster analysis was performed using facets as clustering variables. Multivariable regression analysis was performed to identify the PID-5 characteristics which could suggest a dissociative dimension.</div></div><div><h3>Results</h3><div>Our results showed the potential of PID-5 to hypothesize a dissociative dimension towards DES scores. Therefore, we theorized a specific BPD phenotype characterized by high levels of Unusual Behaviors and Beliefs, high levels of Perceptual Dysregulation, high levels of Withdrawal, low levels of Impulsivity and Irritability, low levels of Callousness and low levels of Avoidance, for which it may be assumed a dissociative framework. Moreover, it could be postulated that patients with dissociative symptoms who will be diagnosed with BPD according to the AMDP would have the domain of Psychoticism as “specifier”.</div><div>Lastly, we highlighted the role of gender as a moderator between personality traits and dissociative symptoms.</div></div><div><h3>Conclusion</h3><div>Consistently with this study, an initial assessment with PID-5 personality facets may detect an underlying dissociative psychopathology, suggesting significant clinical implications for both treatment and prognosis.</div></div>","PeriodicalId":12045,"journal":{"name":"European Journal of Psychiatry","volume":"39 1","pages":"Article 100283"},"PeriodicalIF":2.5,"publicationDate":"2024-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142701760","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}