Marco DI Monaco, Carlotta Castiglioni, Francesca Bardesono, Marco A Minetto, Chiara Busso, Giuseppe Massazza
{"title":"Prevalent vertebral fractures and the diabetic bone paradox in women who sustain a hip fracture: a cross-sectional study.","authors":"Marco DI Monaco, Carlotta Castiglioni, Francesca Bardesono, Marco A Minetto, Chiara Busso, Giuseppe Massazza","doi":"10.23736/S1973-9087.25.08894-X","DOIUrl":"https://doi.org/10.23736/S1973-9087.25.08894-X","url":null,"abstract":"<p><strong>Background: </strong>Patients with type 2 diabetes mellitus (T2DM) have enhanced fracture risk despite high bone mineral density (BMD), a phenomenon known as the diabetic bone paradox. Consistently with the paradox, hip fractures occur at higher BMD in women with T2DM than in controls. However, no studies have addressed BMD in women with T2DM who have prevalent vertebral fractures at the time of their first hip fracture.</p><p><strong>Aim: </strong>The aim of this study was to test the hypothesis that BMD levels could be higher in the hip-fracture women with versus without T2DM in the absence but not in the presence of prevalent vertebral fractures.</p><p><strong>Design: </strong>This was a cross-sectional study.</p><p><strong>Setting: </strong>The research took place in a rehabilitation ward.</p><p><strong>Population: </strong>The study involved women who were undergoing inpatient rehabilitation following a subacute hip fracture.</p><p><strong>Methods: </strong>We investigated hip-fracture women with and without prevalent vertebral fractures, consecutively admitted to our rehabilitation ward. At a median of 19 days after the hip fracture we assessed femoral BMD by dual-energy X-ray absorptiometry and prevalent vertebral fractures by X-ray examination.</p><p><strong>Results: </strong>The study sample included 504 women. One hundred eighty-five of the 504 had no vertebral fractures whereas 319 had at least one spine fracture. The 185 women without vertebral fractures had BMD higher in the presence (N.=29) than in the absence (N.=156) of T2DM (mean T-score difference was 0.67, 95% confidence interval (CI) from 0.31 to 1.03, P<0.001). After adjustment for 8 potential confounders, the odds ratio to have densitometric osteoporosis for a woman without T2DM was 3.21 (95% CI from 1.10 to 9.33, P=0.032). On the contrary, in the 319 women with vertebral fractures T2DM was not associated with BMD.</p><p><strong>Conclusions: </strong>At the time of an original hip fracture, we found a BMD gap between women with and without T2DM in the absence but not in the presence of prevalent vertebral fractures.</p><p><strong>Clinical rehabilitation impact: </strong>Adjustments of fracture risk calculation in T2DM have been authoritatively suggested, because high BMD levels may falsely lead to risk underestimation. Our data suggests that no adjustments may be needed for the risk estimation in patients with prevalent vertebral fractures. Further data from longitudinal studies are needed to define the role of both prevalent vertebral fractures and BMD in fracture risk of patients with T2DM.</p>","PeriodicalId":12044,"journal":{"name":"European journal of physical and rehabilitation medicine","volume":" ","pages":""},"PeriodicalIF":3.3,"publicationDate":"2025-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144625660","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Peiming Chen, Shamay S Ng, Cynthia Y Lai, Samantha M Chan, C Lau, H Wong, Jacqueline H Liang, Christy S Tam, J Li, Tai-Wa Liu, Thomson W Wong, Billy C So, Richard H Xu, Mimi M Tse
{"title":"Psychometric validation of comprehensive coordination scale to assess the advanced coordination ability in people with stroke.","authors":"Peiming Chen, Shamay S Ng, Cynthia Y Lai, Samantha M Chan, C Lau, H Wong, Jacqueline H Liang, Christy S Tam, J Li, Tai-Wa Liu, Thomson W Wong, Billy C So, Richard H Xu, Mimi M Tse","doi":"10.23736/S1973-9087.25.08784-2","DOIUrl":"https://doi.org/10.23736/S1973-9087.25.08784-2","url":null,"abstract":"<p><strong>Background and aim: </strong>The aims of this study were to investigate the psychometric property of the Comprehensive Coordination Scale (CCS) in people with stroke.</p><p><strong>Design: </strong>Cross-sectional design.</p><p><strong>Setting: </strong>University based neurorehabilitation laboratory.</p><p><strong>Population: </strong>Sixty-two people with stroke (33 men; mean ages=67.1±6.4 years; 8.8±4.9 years) and 31 healthy older adults (10 men, mean ages=65.9±4.2 years).</p><p><strong>Methods: </strong>CCS was conducted on the subjects, followed with ARAT, BBS, LOS, MoCA, and SF-12muscle strength test, Fugl-Meyer Assessment of Lower Extremity (FMA-LE) and Upper Extremity (FMA-UE), muscle strength, Montreal Cognitive Assessment (MoCA), Action Research Arm Test (ARAT), Berg Balance Scale (BBS), Limit of Stability (LOS) test and 12-Item Short Form Survey (SF12).</p><p><strong>Results: </strong>There was a significant difference (P<0.001) of CCS score between people with stroke (mean difference=48.0±13.5) and healthy older adults (mean difference=62.9±12.1). CCS showed excellent test-retest reliability (intraclass correlation coefficient (ICC)=0.953). The CCS-Total Score showed a significant positive correlation with the average muscle strength of affected side (dorsiflexors, plantarflexors, elbow flexor, and elbow extensor), FMA-UE score, FMA-LE Score, BBS Score, ARAT Score, and LOS (EE and ME) (r=0.387-0.857, P<0.007) in this study. The CCS-total score of 62.5 (sensitivity 83.9%; specificity of 83.9%; AUC=0.892, P<0.001) was shown to distinguish the walking performance between people with stroke and healthy older adults.</p><p><strong>Conclusions: </strong>The CCS is a reliable, valid and objective assessment tool for evaluating the motor coordination in people with stroke. The CCS exhibited good diagnostic power for distinguishing the coordination ability of individuals with stroke from that of healthy older adults.</p><p><strong>Clinical rehabilitation impact: </strong>Therefore, the CCS is recommended for use in clinical settings to provide a detailed and comprehensive assessment of motor coordination impairment in stroke survivors.</p>","PeriodicalId":12044,"journal":{"name":"European journal of physical and rehabilitation medicine","volume":" ","pages":""},"PeriodicalIF":3.3,"publicationDate":"2025-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144625661","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yi-Wen Bai, Yu-Chen Wang, Xue Jiang, Xia Bi, Wen-Yuan Xing, Le Tang, Pei-Jie Chen, Xue-Qiang Wang
{"title":"Prevalence and risk factors of neck pain among middle-aged and older adults in China: a cross-sectional study from the CHARLS cohort.","authors":"Yi-Wen Bai, Yu-Chen Wang, Xue Jiang, Xia Bi, Wen-Yuan Xing, Le Tang, Pei-Jie Chen, Xue-Qiang Wang","doi":"10.23736/S1973-9087.25.08492-8","DOIUrl":"https://doi.org/10.23736/S1973-9087.25.08492-8","url":null,"abstract":"<p><strong>Aim: </strong>To investigate neck pain prevalence and risk factors pain in China.</p><p><strong>Design: </strong>Cross-sectional analysis using data from the China Health and Retirement Longitudinal Study.</p><p><strong>Setting: </strong>Nationwide study conducted in China.</p><p><strong>Population: </strong>Adults aged 45 years or older.</p><p><strong>Methods: </strong>The data for the study were from the China Health and Retirement Longitudinal Study. A total of 19816 representative subjects were selected by multi-stage stratified sampling method. Univariable and multivariable logistic regression analyses were conducted to identify potential risk factors for neck pain.</p><p><strong>Results: </strong>The estimated prevalence of neck pain among Chinese people over 45 was 18.93% (95% CI 18.32-19.55). Neck pain prevalence significantly differed according to sex, with an overall rate of 12.26% in men and 25.04% in women (P<0.001 for sex difference). Risk factors for neck pain included female (odds ratio [OR] 1.83, 95% CI 1.61-2.08), depression (1.23, 1.06-1.42), short sleep time (1.48,1.31-1.68), more than one chronic condition (1.18, 1.04-1.35), headache (4.83, 4.28-5.47), poor health status (2.93, 2.18-3.92), limitation of physical activity (1.37,1.21-1.57) and activity of daily living (1.48, 1.31-1.68). A lower risk of neck pain was associated with age over 75 and illiterate.</p><p><strong>Conclusions: </strong>The Prevalence of neck pain in China is relatively high. These results may help to develop proper prevention and treatment measures for patients with neck pain.</p><p><strong>Clinical rehabilitation impact: </strong>Our study provides insights for rehabilitating neck pain in adults aged 45 or older, aiding targeted interventions and preventive measures.</p>","PeriodicalId":12044,"journal":{"name":"European journal of physical and rehabilitation medicine","volume":" ","pages":""},"PeriodicalIF":3.3,"publicationDate":"2025-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144607818","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Marco Franceschini, Carrie-Louise Thouant, Maurizio Agosti, Francesca Gimigliano, Salvatore Ferro, Jacopo Bonavita, Maria C Pagliacci, Giorgio Felzani, Sanaz Pournajaf
{"title":"Multicenter study on predictors of rehabilitation outcome and home discharge in people with non-traumatic spinal cord injuries.","authors":"Marco Franceschini, Carrie-Louise Thouant, Maurizio Agosti, Francesca Gimigliano, Salvatore Ferro, Jacopo Bonavita, Maria C Pagliacci, Giorgio Felzani, Sanaz Pournajaf","doi":"10.23736/S1973-9087.25.08777-5","DOIUrl":"https://doi.org/10.23736/S1973-9087.25.08777-5","url":null,"abstract":"<p><strong>Background: </strong>Non-traumatic spinal cord injuries (NTSCI) represent an increasing public health concern, particularly in aging populations, yet there is limited literature on rehabilitation outcomes and key predictors of home discharge in this population.</p><p><strong>Aim: </strong>This study evaluates the impact of demographic and clinical characteristics on rehabilitation outcomes and home discharge rates in individuals with NTSCI.</p><p><strong>Design: </strong>Prospective observational cohort study.</p><p><strong>Setting: </strong>Thirty-one specialized SCI centers in 13 Italian regions.</p><p><strong>Population: </strong>Individuals with NTSCI.</p><p><strong>Methods: </strong>Demographic and clinical characteristics of 394 rehabilitation were recorded at admission (T1) and discharge (T2). The American Spinal Injury Association (ASIA) Scale and Spinal Cord Independence Measure (SCIM) were used to assess motor function and functional independence. Binary logistic regression was employed to develop a predictive model for home discharge, incorporating categorical and continuous variables. Two common metrics for this purpose are the Akaike Information Criterion (AIC) and the Bayesian Information Criterion (BIC). Predictive factors for home discharge were analyzed using logistic regression and ROC curves.</p><p><strong>Results: </strong>80% of participants were discharged home. Key predictors of home discharge included higher SCIM scores, younger age, and being married. The SCIM score at discharge was a stronger predictor of home discharge than at admission. Length of stay (LOS) was also a significant factor, with longer stays associated with better functional outcomes, particularly in individuals with severe impairments.</p><p><strong>Conclusions: </strong>SCIM scores at discharge, age, and marital status emerged as key predictors of home discharge, highlighting the importance of personalized rehabilitation strategies and structured discharge planning. Tailoring rehabilitation programs to maximize SCIM score improvements may enhance home discharge rates and long-term patient outcomes.</p><p><strong>Clinical rehabilitation impact: </strong>This study emphasizes the importance of continuous functional assessment using SCIM during rehabilitation, allowing clinicians to optimize treatment plans and improve home discharge likelihood. Additionally, considering demographic factors such as age and marital status in discharge planning may facilitate better reintegration into home environments. Longer rehabilitation stays for individuals with more severe injuries (ASIA A/B) can significantly enhance outcomes. By incorporating these predictors into everyday practice, rehabilitation clinics can better optimize patient care, increase home discharge rates, and improve overall quality of life post-rehabilitation.</p>","PeriodicalId":12044,"journal":{"name":"European journal of physical and rehabilitation medicine","volume":" ","pages":""},"PeriodicalIF":3.3,"publicationDate":"2025-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144607817","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Psychometric validation of ICF Rehabilitation Set-17 through item response theory and network analysis: implications for standardized functioning assessment in Chinese inpatient rehabilitation.","authors":"Chun Feng, Cong-Zhi Tang, Feng Lin, Shou-Guo Liu","doi":"10.23736/S1973-9087.25.08759-3","DOIUrl":"10.23736/S1973-9087.25.08759-3","url":null,"abstract":"<p><strong>Background: </strong>The International Classification of Functioning, Disability and Health (ICF) offers a comprehensive biopsychosocial model widely used to capture functioning and disability status. The development of the national assessment standard regarding the ICF-Rehabilitation Set (ICF-RS)-17 represents the first step in implementing value-based healthcare (VBHC) in China. However, studies relating the ICF to managing goal setting and guiding VBHC are scarce.</p><p><strong>Aim: </strong>This study aims to investigate the psychometric properties of the ICF-17 and further tailor goal settings in inpatient rehabilitation settings.</p><p><strong>Design: </strong>A multi-centered, cross-sectional study.</p><p><strong>Setting: </strong>Three general hospitals and two rehabilitation hospitals in Jiangsu Province, China.</p><p><strong>Population: </strong>Patients received inpatient rehabilitation treatment.</p><p><strong>Methods: </strong>We administrated ICF-RS-17 and Barthel index to assess inpatient patients' function, and quality of life with the Short Form-12 (SF-12). We performed a non-parametric and parametric Item response modeling (IRM) pipeline as a psychometric measurement. We further constructed graphical modeling (GM) to visualize the network structure of functional categories and calculate the treatment benefit index (TBI).</p><p><strong>Results: </strong>The 2-parametric logistic model (2PLM) emerged as the optimal model generating a unidimensional scale with 17 ICF items (9 'd - Activities and Participation', 8 'b - Body Functions'). The final scale presented strong reliability with a latent class reliability coefficient=0.963, indicating great internal reliability. The estimated individual functional competence by the 2PLM model was moderately related to the index score of the PCS (p = 8.68 × 10<sup>-114</sup>, ȓPearson = 0.52) and MCS (p = 7.41 × 10<sup>-45</sup>, ȓPearson = 0.34), as well as a strong positive correlation with the BI (p = 7.41 × 10<sup>-45</sup>, ȓPearson = 0.81). The findings also demonstrated measurement equivalence of the final model for individuals with different gender and across age groups as well as different measurement points (e.g. admission and discharge). Moreover, the GM indicates \"d510 Washing oneself\" possesses the most potent alleviating effect in the functional network (perturbance power=1.019).</p><p><strong>Conclusions: </strong>The IRM-verified ICF-RS-17 tool has good construct validity and internal consistency for assessing the inpatient functional level. Moreover, enhancing \"d510 Washing oneself\" ability demonstrates the highest benefit for overall functional performance.</p><p><strong>Clinical rehabilitation impact: </strong>The IRM might be helpful in facilitating person ability-matched goal setting by comparing person abilities and item difficulties along the same logit scale. GM visualizes the spread and perturbance power of functional limitations within the network model, wh","PeriodicalId":12044,"journal":{"name":"European journal of physical and rehabilitation medicine","volume":" ","pages":""},"PeriodicalIF":3.3,"publicationDate":"2025-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144332699","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aminu A Ibrahim, Katayan Klahan, Kanphajee Sornkaew, Jarugool Tretriluxana, Sheri P Silfies, Peemongkon Wattananon
{"title":"Exploring the therapeutic potential of transcranial direct current stimulation for chronic low back pain: a scoping review.","authors":"Aminu A Ibrahim, Katayan Klahan, Kanphajee Sornkaew, Jarugool Tretriluxana, Sheri P Silfies, Peemongkon Wattananon","doi":"10.23736/S1973-9087.25.08870-7","DOIUrl":"https://doi.org/10.23736/S1973-9087.25.08870-7","url":null,"abstract":"<p><strong>Introduction: </strong>Chronic low back pain (CLBP) is a common disabling condition, inflicting a substantial socioeconomic burden. Given its association with neuroplastic changes, as evidenced by central and peripheral sensitization, neuromodulatory techniques such as transcranial direct current stimulation (tDCS) have emerged as potential treatments. This scoping review aimed to identify and map the existing literature on tDCS studies for CLBP to provide insight into how these studies are conducted, and to address their potential gaps in knowledge.</p><p><strong>Evidence acquisition: </strong>PubMed, Embase, Web of Science, and Cochrane Library were searched for relevant studies from inception to 23 March 2025. Eligible studies included were those examining tDCS alone or with other interventions in adults with CLBP, regardless of the outcome evaluated and included adults with CLBP. The review was conducted using Arksey and O'Malley's six-stage framework and was guided by the PRISMA for scoping review framework.</p><p><strong>Evidence synthesis: </strong>Of 134 screened records, 26 studies were included: 23 randomized controlled trials and 3 quasi-experimental studies. Half of the studies (50%) had a low risk of bias while one-third (34.6%) showed a high or serious risk of bias. Outcomes evaluated varied and included clinical, biophysical, biomechanical, and psychosocial measures. There was considerable variability in tDCS treatment protocols across studies. The effectiveness of tDCS was inconsistent, particularly for clinical outcomes, with some studies indicating positive effects while others reported no significant effects.</p><p><strong>Conclusions: </strong>Overall, this review reveals inconsistent results for tDCS effectiveness in CLBP, likely due to variability in study designs, sample characteristics, treatment protocols, and outcome measures. Future well-designed trials are needed to clarify the therapeutic potential of tDCS for CLBP, particularly in combination with other interventions.</p>","PeriodicalId":12044,"journal":{"name":"European journal of physical and rehabilitation medicine","volume":" ","pages":""},"PeriodicalIF":3.3,"publicationDate":"2025-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144324831","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Repetitive peripheral magnetic stimulation for pain, disability, and kinesiophobia in patients with chronic musculoskeletal pain: a systematic review and meta-analysis.","authors":"Jiaxin Pan, Yanbing Jia, Kuicheng Li, Xiaoyan Liu, Zhichao Liu, Zhenyang Cui, Linrong Liao, Yingxiu Diao, Hao Liu","doi":"10.23736/S1973-9087.25.08442-4","DOIUrl":"https://doi.org/10.23736/S1973-9087.25.08442-4","url":null,"abstract":"<p><strong>Introduction: </strong>Repetitive peripheral magnetic stimulation (rPMS) is a non-invasive and painless approach developed for therapeutic intervention in clinical rehabilitation. Chronic musculoskeletal pain (CMP) originates from the musculoskeletal system and leads to disability and fear of pain. It may be an option for CMP treatment, but its effectiveness is still unclear.</p><p><strong>Evidence acquisition: </strong>PubMed, PEDro, the Cochrane Library, Web of Science, and Embase were searched for relevant literatures according to strict inclusion and exclusion criteria on May 26<sup>th</sup>, 2023.</p><p><strong>Evidence synthesis: </strong>The methodology quality of the included studies was assessed using the Cochrane Collaboration's Risk of Bias tool (ROB 2.0) and the GRADE (Grading of Recommendations, Assessment, Development, and Evaluation) system. The cumulative effects of available data were processed for a meta-analysis using RevMan software. Eight RCTs with 177 participants were included. All studies were assessed as having some concerns regarding the risk of bias. rPMS significantly reduced pain intensity compared with the control, with a standardized mean difference (SMD) across visual analogue scales (VAS) and numerical rating scales (NRS) was -1.16 (95% CI: -1.56 to -0.76, I<sup>2</sup>=21%, very low-quality evidence), indicating effective pain relief. For subgroup analysis of patients with chronic low back pain (CLBP), the meta-analysis revealed a remarkable pain relief (SMD=-0.92, 95% CI: -1.67 to -0.17, I<sup>2</sup>=45%, very low-quality evidence). In addition, rPMS exhibited significant cumulative effects on disability improvement (Oswestry disability index: MD=-6.55, 95% CI: -10.27 to -2.82, I<sup>2</sup>=0%, very low-quality evidence) but not on kinesiophobia (Tampa scale for kinesiophobia: MD=-1.81, 95% CI: -7.60 to 3.98, I<sup>2</sup>=0%, low quality-evidence).</p><p><strong>Conclusions: </strong>This meta-analysis demonstrated that rPMS is an effective method for relieving pain and improving disability in the treatment of CMP, especially for patients with CLBP.</p>","PeriodicalId":12044,"journal":{"name":"European journal of physical and rehabilitation medicine","volume":" ","pages":""},"PeriodicalIF":3.3,"publicationDate":"2025-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144274445","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mert Zure, Mahir Topaloğlu, Sina Arman, Ayşegül Ketenci
{"title":"The effect of blood flow restricted aerobic exercise training on pain, functional status, quality of life and hormonal response to exercise in fibromyalgia patients: a randomized double-blind study.","authors":"Mert Zure, Mahir Topaloğlu, Sina Arman, Ayşegül Ketenci","doi":"10.23736/S1973-9087.25.08817-3","DOIUrl":"https://doi.org/10.23736/S1973-9087.25.08817-3","url":null,"abstract":"<p><strong>Background: </strong>Fibromyalgia is a chronic pain condition with symptoms such as pain, fatigue, and decreased quality of life. Although aerobic exercise is an effective treatment for fibromyalgia, patients often struggle with exercise intolerance due to fatigue, limiting long-term adherence. Research on blood flow-restricted (BFR) exercise suggests it may provide benefits similar to traditional exercise with reduced intensity, but its effects on fibromyalgia-related symptoms remain underexplored.</p><p><strong>Aim: </strong>This study investigated the impact of a BFR aerobic exercise program on pain, functional status, quality of life, and hormonal response in women with fibromyalgia.</p><p><strong>Design: </strong>A prospective, randomized, double-blind, sham-controlled trial.</p><p><strong>Setting: </strong>Outpatient rehabilitation center.</p><p><strong>Population: </strong>Fifty women diagnosed with fibromyalgia were included in this study.</p><p><strong>Methods: </strong>Participants were randomly assigned to two groups receiving supervised aerobic exercise four times weekly for six weeks. The experimental group used blood flow restriction aid with elastic bandages at the groin level, while the control group received a sham restriction. Primary outcomes were assessed with the Fibromyalgia Impact Questionnaire (FIQ). Secondary outcomes included the Central Sensitization Index (CSI), Beck Depression Inventory (BDI), Visual Analogue Scale (VAS) for pain, Chronic Pain Acceptance Questionnaire-8 (CPAQ-8), and 24-hour urine levels of vanillyl mandelic acid (VMA) and 5-hydroxy indole acetic acid (5-HIAA). Evaluations were conducted before, immediately after, and three months post-intervention.</p><p><strong>Results: </strong>The mean age of participants was 43.2±7.2 years, with comparable baseline characteristics between groups. Both groups showed significant improvements across all outcomes, with the BFR group exhibiting superior improvements in FIQ (P<0.001), CSI, and BDI scores, as well as increased urine levels of VMA and 5-HIAA. Although both groups improved in pain and pain acceptance, these changes were not significantly different between groups.</p><p><strong>Conclusions: </strong>Patients with fibromyalgia who have limited exercise tolerance may find that BFR aerobic exercise improves pain, function, central sensitization, mood, and catecholamine-serotonin levels. Additional research is needed to further understand its effects and broaden the scope of this technique in the treatment of fibromyalgia.</p><p><strong>Clinical rehabilitation impact: </strong>BFR aerobic training could improve adherence to exercise therapy in fibromyalgia by offering a lower-intensity alternative with enhanced benefits, potentially leading to better symptom management in clinical settings.</p>","PeriodicalId":12044,"journal":{"name":"European journal of physical and rehabilitation medicine","volume":" ","pages":""},"PeriodicalIF":3.3,"publicationDate":"2025-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144156628","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Psychometric assessment of the translated and culturally adapted Chinese (Cantonese) of the brief memory and executive test in people with stroke.","authors":"Longjun Ren, Thomson Wong, Cynthia Lai, Shamay Ng","doi":"10.23736/S1973-9087.25.08873-2","DOIUrl":"https://doi.org/10.23736/S1973-9087.25.08873-2","url":null,"abstract":"<p><strong>Background: </strong>Stroke is a leading cause of death and disability, with up to half of people with stroke developing persistent cognitive deficits. The brief memory and executive test (BMET) was developed to provide a comprehensive cognitive assessment, with a focus on executive function and processing speed. However, the psychometric properties of the BMET have not yet been studied in people with stroke.</p><p><strong>Aim: </strong>This study aimed to: 1) translate and culturally adapt the BMET into Chinese (Cantonese) (C-BMET); 2) compare the C-BMET scores of people with stroke with those of healthy old adults; 3) examine the internal consistency, test-retest reliability, minimal detectable change (MDC), and standard error of measurement (SEM) of the C-BMET in people with stroke; 4) investigate correlations between C-BMET scores and other cognitive and functional outcomes; and 5) determine the C-BMET cut-off score of C-BMET to differentiate the cognitive functions in people with stroke from that of healthy old adults.</p><p><strong>Design: </strong>Cross-sectional.</p><p><strong>Setting: </strong>Research lab in the Hong Kong Polytechnic University.</p><p><strong>Population: </strong>People with stroke over 12 months.</p><p><strong>Methods: </strong>Sixty people with stroke and 27 healthy old adults underwent C-BMET and other cognitive and functional outcomes. To examine the test-retest reliability of the C-BMET, it was re-administered to the stroke group after 7 days.</p><p><strong>Results: </strong>People with stroke had significantly lower C-BMET subtotal and total scores compared to healthy old adults. The internal consistency, as indicated by Cronbach's α of 0.652, and the test-retest reliability, reflected by an intra-class correlation coefficient of 0.604, were observed, with an MDC of 4.13 and a SEM of 1.49. The C-BMET scores were significantly correlated with other cognitive outcomes but not with functional outcomes. The optimal cut-off score of C-BMET to differentiate the cognitive functions in people with stroke from that of the and healthy old adults was 12.5 (area under the receiver operating characteristic curve = 0.728).</p><p><strong>Conclusions: </strong>The C-BMET scores were significantly lower in people with stroke compared with healthy old adults. The internal consistency and test-retest reliability of C-BMET scores were investigated. The C-BMET scores were significantly correlated with cognitive outcomes. The optimal C-BMET cut-off score of 12.5 was identified.</p><p><strong>Clinical rehabilitation impact: </strong>The C-BMET may be considered for assessing the cognitive function, especially executive function and processing speed, of people with stroke.</p>","PeriodicalId":12044,"journal":{"name":"European journal of physical and rehabilitation medicine","volume":" ","pages":""},"PeriodicalIF":3.3,"publicationDate":"2025-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143958046","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Emily J Thomas, William J Taylor, Richard J Siegert, William M Levack
{"title":"Brain Injury Sense of Self Scale: psychometric development of a new measure of strength of self-identity after traumatic brain injury.","authors":"Emily J Thomas, William J Taylor, Richard J Siegert, William M Levack","doi":"10.23736/S1973-9087.25.08721-0","DOIUrl":"https://doi.org/10.23736/S1973-9087.25.08721-0","url":null,"abstract":"<p><strong>Background: </strong>There is growing awareness that traumatic brain injury (TBI) can have a significant and troublesome impact of a person's self-identity, yet few measurement tools exist to clinically evaluate this.</p><p><strong>Aim: </strong>The aim of this paper was to develop a patient-reported measure of strength of self-identity after TBI - the Brain Injury Sense of Self Scale (BISOSS).</p><p><strong>Design: </strong>Measurement development and validation.</p><p><strong>Setting: </strong>UK and New Zealand communities.</p><p><strong>Population: </strong>One hundred and thirty-six people with TBI (68.4% [93/136]) male; mean age 47.9 years, SD 13.0 years; mean time post-TBI 11.2 years, SD 11.1 years; 74.3% (101/136) moderate to severe TBI).</p><p><strong>Methods: </strong>Preliminary measurement items were generated from prior qualitative research, a concept analysis, and cognitive interviewing with survivors of TBI. Administration of the draft BISOSS, the Glasgow Outcome Scale, and the Sense of Coherence Scale to participants - with factor analysis, Rasch analysis, and construct validity testing to refine and test the draft BISOSS.</p><p><strong>Results: </strong>After iterative refinements using the Rasch model to help guide item adjustments, BISOSS was comprised of three subscales (egocentric self, sociocentric self, and relational self), each which fit the Rasch model and demonstrated unidimensionality, adequate precision, absence of differential item functioning and adequate person separation index. BISOSS scores correlated well with employment status, leisure activities and positive family relationships. Participants' responses supported the notion that problems with self-identity were commonplace after TBI, with 40% of respondents self-reporting such problems.</p><p><strong>Conclusions: </strong>BISOSS is a valid measure, which conforms to measurement expectations for an interval scale and is in grounded in the language of people with TBI. It is now available as a validated tool for assessing self-identity issues post-TBI. Further work is required to assess whether the scale can change over time or is responsive to interventions targeted at strengthening self-identity.</p><p><strong>Clinical rehabilitation impact: </strong>Change in self-identity is a commonplace problem following TBI but is seldomly evaluated in clinical practice. BISOSS can be used to explore patient experiences of problems with self-identity after TBI and will help further our understanding of this phenomenon.</p>","PeriodicalId":12044,"journal":{"name":"European journal of physical and rehabilitation medicine","volume":" ","pages":""},"PeriodicalIF":3.3,"publicationDate":"2025-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143980416","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}