European journal of general medicine最新文献_第7页

Pott's Puffy tumor: The role of ultrasound, computed tomography and magnetic resonance imaging in diagnosis 波氏浮肿瘤:超声、计算机断层扫描和磁共振成像在诊断中的作用

European journal of general medicine Pub Date : 2017-04-06 DOI: 10.29333/EJGM/81883

H. Kalkan, M. Eryılmaz, D. Kiresi, H. Arbağ, A. Yesildag

引用次数: 0

Biomarkers of endothelial function and insulin resistance response to aerobic exercise versus resistance exercises in obese type 2 diabetic patients 肥胖2型糖尿病患者有氧运动与抵抗运动对内皮功能和胰岛素抵抗反应的生物标志物

European journal of general medicine Pub Date : 2017-04-06 DOI: 10.29333/EJGM/81880

F. Al-Shreef, S. El-Kader

{"title":"Biomarkers of endothelial function and insulin resistance response to aerobic exercise versus resistance exercises in obese type 2 diabetic patients","authors":"F. Al-Shreef, S. El-Kader","doi":"10.29333/EJGM/81880","DOIUrl":"https://doi.org/10.29333/EJGM/81880","url":null,"abstract":"Introduction:The risk of endothelial dysfunction and insulin resistance is higher in type 2 diabetes mellitus (T2DM) which could be modulated with exercise training. However, to our knowledge, there is no clinical studies have addressed which exercise specific type is superior in modulating biomarkers of endothelial dysfunction and insulin resistance for T2DM.This study aimed to determine the differences in response of biomarkers of endothelial dysfunction and insulin resistance to aerobic versus resistance exercises in type 2 diabetic patients.Material and Methods:Eighty obese type 2 diabetic patients participated in this study and were included into two groups, group (A) received aerobic exercises; where group (B) received resistance exercises for 12 months.Results:The mean values of Inter-Cellular Adhesion Molecule (ICAM-1), Vascular Cell Adhesion Molecule (VCAM-1), tissue plasminogen activator (tPA), E-selectin, glycosylated hemoglobin (HBA1c) and Homeostasis Model Assessment-Insulin Resistance (HOMA-IR) were significantly decreased in both groups at the end of the study. However, the mean values of ICAM-1, VCAM-1 and t-PA antigen were more significantly reduced in group (A), while the mean values of HBA1c and HOMA-IR were more significantly reduced in group (B) and there were significant differences between both groups at the end of the study.Conclusions:Resistance exercise appears to be more beneficial than aerobic exercise for improving insulin resistance in T2DM. Also, aerobic exercise appears to be more beneficial than resistance exercise for improving endothelial function in T2DM.","PeriodicalId":12017,"journal":{"name":"European journal of general medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-04-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81918433","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Pilomyxoid astrocytoma showing malignant transformation in adult male 成年男性毛粘液样星形细胞瘤表现为恶性转化

European journal of general medicine Pub Date : 2017-01-06 DOI: 10.29333/EJGM/81877

S. Fındık, H. Esen, M. Erdi, Pembe Oltulu, Naile Kökbudak, S. Gungor

引用次数: 0

Placental chorioangioma complicated with preterm delivery: A case report 胎盘绒毛膜血管瘤合并早产1例

European journal of general medicine Pub Date : 2017-01-05 DOI: 10.29333/EJGM/81873

C. Inan, N. C. Sayın, E. Taştekin, Selen Gursoy-Erzincan, I. Uzun, Nurtaç Sarikaş, F. Varol

引用次数: 2

Tuberculoma presenting as isolated sixth nerve palsy: A rare case report 结核瘤表现为孤立性第六神经麻痹:罕见病例报告

European journal of general medicine Pub Date : 2017-01-05 DOI: 10.29333/EJGM/81875

D. Jain, H. Aggarwal, A. Rao, Shaveta Dahiya

引用次数: 1

Risk factors for hepatotoxicity in patients hospitalized for tuberculosis 肺结核住院患者肝毒性的危险因素

European journal of general medicine Pub Date : 2017-01-05 DOI: 10.29333/EJGM/81870

B. Ergan, E. Kirmizigul, O. Uzun, L. Coplu

{"title":"Risk factors for hepatotoxicity in patients hospitalized for tuberculosis","authors":"B. Ergan, E. Kirmizigul, O. Uzun, L. Coplu","doi":"10.29333/EJGM/81870","DOIUrl":"https://doi.org/10.29333/EJGM/81870","url":null,"abstract":"Introduction:Combination therapy with four drugs (isoniazid, rifampicin, pyrazinamid and ethambutol) is the treatment of choice in tuberculosis but hepatotoxicity due to these drugs is an important medical concern. Therefore identification of patient groups with increased risk for antituberculosis therapy induced hepatotoxicity is crucial.Material and Methods:This retrospective cohort study included hospitalized patients with the diagnosis of tuberculosis during a ten year period. Only patients with microbiological (culture positive) or histopathological (presence of granulomatous reaction with caseification necrosis in the tissue) evidence of tuberculosis infection were included. Incidence of hepatotoxicity and the association of hepatotoxicity with known and unknown risk factors were investigated.Results:Sixty four patients (33 female-31 male; median age 48.0 years) were included into the study. Most of the patients had extrapulmonary tuberculosis (n=49). Antituberculosis therapy was started with four drugs in all patients and 7 patients developed hepatotoxicity. Age, gender, previous tuberculosis history, extent of tuberculosis, positive hepatitis B virus serology, diabetes mellitus and chronic renal insufficiency were not related with the development of hepatotoxicity. The presence of rheumatologic disease and chronic corticosteroid use was associated with increased risk of hepatotoxicity (p<0.01 and p=0.01, respectively).Conclusions:In this study we found that patients with rheumatologic diseases and patients on chronic corticosteroid treatment had increased risk for hepatotoxicity during antituberculosis therapy. These patients should be closely monitored for hepatotoxicity especially during the initial treatment phase.Objective:To assess the rate of hepototoxicity due to antituberculosis drugs and to determine factors associated with hepatotoxicity in hospitalized tuberculosis patients.","PeriodicalId":12017,"journal":{"name":"European journal of general medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-01-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86517898","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Is liquid-based cervical cytology test more effective than conventional pap smear? 液体子宫颈细胞学检查是否比传统子宫颈抹片检查更有效?

European journal of general medicine Pub Date : 2017-01-05 DOI: 10.29333/EJGM/81871

İlknur Alkan-Kuşabbi, H. Aydoğmuş, H. Işık, A. Seven, B. Yuksel, Gülenay Gençosmanoğlu-Türkmen, D. Karçaaltıncaba, Y. Ergün, M. Çaydere, S. Batıoğlu

{"title":"Is liquid-based cervical cytology test more effective than conventional pap smear?","authors":"İlknur Alkan-Kuşabbi, H. Aydoğmuş, H. Işık, A. Seven, B. Yuksel, Gülenay Gençosmanoğlu-Türkmen, D. Karçaaltıncaba, Y. Ergün, M. Çaydere, S. Batıoğlu","doi":"10.29333/EJGM/81871","DOIUrl":"https://doi.org/10.29333/EJGM/81871","url":null,"abstract":"Introduction:To evaluate and compare the efficiencies of cytologic test methods conventional Pap smear (CVS) versus Thin Prep liquid-based cytology technique (TPT) in the histologic diagnosis of the precancerous lesions of the cervix and cervical cancer.Material and Methods:We selected randomly 1203 non-gravid women who were admitted to gynecology and menopause out-patient clinics of our hospital in the study. The cervical smear tests of all women were evaluated both using the conventional Pap smear and the TPT. Cytological examinations were compared according to their adequacy for evaluation. The evaluation of samples were performed and compared according to The Bethesda System.Results:The two screening methods were statistically compatible for evaluating the samples (κ=0,379 and p<0,001). The diagnosis interpreted by CPS and TPT methods were synchronous and this was also statistically significant (ĸ=0,829 ve p<0,001).Conclusions:Our cytohistologic diagnoses and samples' adequacy interpreted with CVS and TPT were statistically significantly synchronous.","PeriodicalId":12017,"journal":{"name":"European journal of general medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-01-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85269571","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Spinal extradural Rosai Dorfman disease 脊髓硬膜外Rosai Dorfman病

European journal of general medicine Pub Date : 2017-01-05 DOI: 10.29333/EJGM/81874

J. James, J. Jose

引用次数: 3

Gluteal region muscle metastasis from squamous cell lung carcinoma 肺鳞状细胞癌臀区肌肉转移

European journal of general medicine Pub Date : 2017-01-05 DOI: 10.29333/EJGM/81876

C. Korkmaz, Ramazan Yolacan, T. Teke, D. M. Yavşan

引用次数: 0

Preoperative MRI versus intraoperative frozen-section in the assessment of myometrial invasion in endometrioid type endometrial cancer 术前MRI与术中冷冻切片对子宫内膜样型子宫内膜癌子宫肌层浸润的评估

European journal of general medicine Pub Date : 2017-01-05 DOI: 10.29333/EJGM/81872

Ceyda Sancakli-Usta, A. Usta, M. Karacan, M. Kanter, F. Ozen, K. Güzin, N. Yucel, Nurver Ozbay-Ozel, M. Takir

{"title":"Preoperative MRI versus intraoperative frozen-section in the assessment of myometrial invasion in endometrioid type endometrial cancer","authors":"Ceyda Sancakli-Usta, A. Usta, M. Karacan, M. Kanter, F. Ozen, K. Güzin, N. Yucel, Nurver Ozbay-Ozel, M. Takir","doi":"10.29333/EJGM/81872","DOIUrl":"https://doi.org/10.29333/EJGM/81872","url":null,"abstract":"In this study, it is aimed to compare the diagnostic accuracy of preoperative magnetic resonance imaging (MRI) and intraoperative frozen section in determining the depth of myometrial invasion in patients with endometrioid type endometrial cancer. Retrospective evaluation of 69 patients with endometrioid type endometrial cancer who underwent preoperative MRI and subsequently intraoperative frozen-section and surgical staging between February 2004 and September 2011. Surgical staging was performed according to 2009 FIGO classification. Final histopathological examination was accepted as the standard of reference. The median age of patients was 59 years (range 41-80 years). Histopathological evaluation revealed that 41 patients had superficial myometrial invasion (<50% of myometrium) and 28 had deep myometrial invasion (≥50% of myometrium). Sensitivity, specificity, positive predictive value, negative predictive value and accuracy were 64.2%, 87.8%, 78.2%, 78.2% and 78.2% for MRI, and 89.3%, 97.6 %, 96.2 %, 93.0 % and 94.2% for frozen-section, respectively. The diagnostic accuracy of the intraoperative frozen-section was significantly higher than that of preoperative MRI according to McNemar’s test (p=0.03). A statistically significant negative correlation was found between MRI accuracy and tumor grade (p=0.0002). None of the other variables was associated with incorrect prediction of MRI. The rate of incorrect prediction of myometrial invasion with frozen-section was significantly higher in nonvisualized tumors (p=0.01). A significant difference was not detected with other variables and frozen-section. Intraoperative frozen section has a better accuracy compared to MRI in the assessment of myometrial invasion in endometrioid type endometrial cancer. MRI seems suboptimal in the identification of invasion to the myometrium.","PeriodicalId":12017,"journal":{"name":"European journal of general medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-01-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81980763","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1