Is liquid-based cervical cytology test more effective than conventional pap smear?

İlknur Alkan-Kuşabbi, H. Aydoğmuş, H. Işık, A. Seven, B. Yuksel, Gülenay Gençosmanoğlu-Türkmen, D. Karçaaltıncaba, Y. Ergün, M. Çaydere, S. Batıoğlu
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引用次数: 2

Abstract

Introduction:To evaluate and compare the efficiencies of cytologic test methods conventional Pap smear (CVS) versus Thin Prep liquid-based cytology technique (TPT) in the histologic diagnosis of the precancerous lesions of the cervix and cervical cancer.Material and Methods:We selected randomly 1203 non-gravid women who were admitted to gynecology and menopause out-patient clinics of our hospital in the study. The cervical smear tests of all women were evaluated both using the conventional Pap smear and the TPT. Cytological examinations were compared according to their adequacy for evaluation. The evaluation of samples were performed and compared according to The Bethesda System.Results:The two screening methods were statistically compatible for evaluating the samples (κ=0,379 and p<0,001). The diagnosis interpreted by CPS and TPT methods were synchronous and this was also statistically significant (ĸ=0,829 ve p<0,001).Conclusions:Our cytohistologic diagnoses and samples' adequacy interpreted with CVS and TPT were statistically significantly synchronous.
液体子宫颈细胞学检查是否比传统子宫颈抹片检查更有效?
目的:评价和比较常规巴氏涂片(CVS)与薄准备液基细胞学技术(TPT)在宫颈和宫颈癌癌前病变的组织学诊断中的效率。材料与方法:随机选取我院妇科及绝经期门诊收治的1203例未妊娠妇女。所有妇女的子宫颈涂片检查均采用传统的巴氏涂片和TPT进行评估。比较细胞学检查的充分性。根据Bethesda系统对样品进行评价和比较。结果:两种筛选方法对样品的评价在统计学上是一致的(κ= 0.379, p< 0.001)。CPS和TPT方法的诊断是同步的,这也有统计学意义(p< 0.001)。结论:我们的细胞组织学诊断和样本的充分性与CVS和TPT解释具有统计学意义上的同步。
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