European journal of general medicine最新文献

Recognizing Limitations: Overcoming Challenges in Enhancing Health and Preventing Disease 认识局限性:克服增进健康和预防疾病方面的挑战

European journal of general medicine Pub Date : 2023-06-13 DOI: 10.31487/j.ejgm.2023.01.01

J. Alzeer, Hamid Benmerabet

{"title":"Recognizing Limitations: Overcoming Challenges in Enhancing Health and Preventing Disease","authors":"J. Alzeer, Hamid Benmerabet","doi":"10.31487/j.ejgm.2023.01.01","DOIUrl":"https://doi.org/10.31487/j.ejgm.2023.01.01","url":null,"abstract":"The advancement of human progress hinges on the ability to identify limitations and develop innovative solutions, particularly in the field of healthcare. While modern medicine has made significant strides in treating various illnesses, it often fails to address the root causes of diseases, impeding the recovery process for many patients. To overcome this challenge, healthcare professionals require a more comprehensive and integrative approach to healthcare that combines rational and logical thinking. Rationality offers a systematic and evidence-based method for understanding and treating diseases, providing healthcare professionals with a strong foundation for developing treatment plans. However, rational thinking has limitations in terms of our observational abilities, which can lead to misdiagnosis and ineffective treatments. On the other hand, logical thinking provides a more creative and flexible approach to problem-solving, which is particularly useful in addressing complex and multifaceted health issues. This approach enables healthcare professionals to think outside the box, consider alternative solutions, and tailor treatment plans to individual needs. By combining rational and logical viewpoints, healthcare providers can enhance their comprehension of a patient's condition, resulting in more favourable treatment results. Halalopathy, which employs a merged thought process, has been introduced to tackle the challenges and limitations of modern medicine. Halalopathy is a holistic healthcare approach that integrates rational and logical thinking, providing a more comprehensive understanding of illness prevention and disease at a physicopsychological level.","PeriodicalId":12017,"journal":{"name":"European journal of general medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90650568","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Stimulation of Vagus By Phenylephrine Increases the Efficiency and Safety of Antidepressants and Anti-Epileptics 苯肾上腺素刺激迷走神经增加抗抑郁药和抗癫痫药的有效性和安全性

European journal of general medicine Pub Date : 2019-11-10 DOI: 10.31487/j.ejgm.2019.01.01

S. Serdyuk, V. Gmiro

{"title":"Stimulation of Vagus By Phenylephrine Increases the Efficiency and Safety of Antidepressants and Anti-Epileptics","authors":"S. Serdyuk, V. Gmiro","doi":"10.31487/j.ejgm.2019.01.01","DOIUrl":"https://doi.org/10.31487/j.ejgm.2019.01.01","url":null,"abstract":"Background: Earlier, we discovered the possibility of potentiation of the therapeutic effects of small (threshold) doses of CNS agents by phenylephrine and adrenaline, while eliminating their side effects. However, the question of the possibility of potentiation by phenylephrine and other CNS potentiators of high therapeutic doses of CNS agents remained unstudied. This study is devoted to the research of this problem.\u0000Objective: The aim of the study was to investigate the effect of the threshold dose of phenylephrine on the antidepressant effect of amitriptyline and the anticonvulsant effect of diazepam, as well as their side sedation in high doses.\u0000Method: The experiments were carried out on the animated models of depression (Porsolt test) and epilepsy (clonic pentylenetetrazole (PTZ)-induced seizures), resistant to antidepressants and antiepileptics even at high therapeutic doses. Side sedative effect of substances was evaluated in the \"open field\" test.\u0000Results: We established that the stimulation of gastric vagal afferents with phenylephrine, when administered orally at threshold doses, potentiates the anticonvulsant effect of diazepam and the antidepressant effect of amitriptyline in high therapeutic doses to the maximum level that is impossible in their application by themselves, and at the same time eliminates their side sedation.\u0000Conclusion: A synergistic effect of phenylephrine and CNS drugs on the peripheral and central links of the vagal stress-protective reflex is discussed. It is assumed that the potentiation of therapeutic effect by phenylephrine and the elimination of side effects of the CNS agents occurs as a result of strengthening the vagal stress-protective reflex, eliminating the drug stress.","PeriodicalId":12017,"journal":{"name":"European journal of general medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-11-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90624075","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

A Rapidly Fatal Case of Lactobacillus Rhamnosus Sepsis Associated with Thyroid Storm in an Immunocompetent Patient 鼠李糖乳杆菌脓毒症与免疫功能正常患者甲状腺风暴相关的快速致命病例

European journal of general medicine Pub Date : 2019-10-21 DOI: 10.31487/j.ejgm.2019.01.02

Nasser Al-Rubai’aan, R. Dhar, W. Alfouzan

引用次数: 0

The Value of Longitudinal Strain versus Coronary Angiography in Detection of Coronary Artery Disease 纵向应变与冠状动脉造影在冠状动脉疾病诊断中的价值

European journal of general medicine Pub Date : 2018-02-01 DOI: 10.31487/J.EJGM.2018.01.001

S. I. Essa

引用次数: 4

Which one in the diagnosis of acute appendicitis: Physical examination, laboratory or imaging? A retrospective analysis in the light of pathological results 诊断急性阑尾炎时，体格检查、实验室检查还是影像学检查?结合病理结果进行回顾性分析

European journal of general medicine Pub Date : 2018-01-17 DOI: 10.29333/ejgm/81764

H. Özdemir, Zehra Özdemir, O. Sunamak, Ferdi Cambaztepe

引用次数: 7

Stem Cells Therapy in General Medicine 普通医学中的干细胞治疗

European journal of general medicine Pub Date : 2018-01-17 DOI: 10.29333/EJGM/83014

A. Gaipov, Askhat Myngbay

引用次数: 2

Effect of sleep duration on muscle mass in Korean non-elderly adults 韩国非老年人睡眠时间对肌肉质量的影响

European journal of general medicine Pub Date : 2018-01-10 DOI: 10.29333/EJGM/81763

J. Moon, M. Kong, Y. Oh, H. Kim

{"title":"Effect of sleep duration on muscle mass in Korean non-elderly adults","authors":"J. Moon, M. Kong, Y. Oh, H. Kim","doi":"10.29333/EJGM/81763","DOIUrl":"https://doi.org/10.29333/EJGM/81763","url":null,"abstract":"Objective:\u0000This study investigated the association of sleep duration and muscle mass in non-elderly adults.\u0000\u0000Methods:\u0000The present study analyzed young (19-39 years) and middle-aged (40-59 years) men and women who participated in the Korea National Health and Nutrition Examination Survey. Muscle mass was measured using dual energy X-ray absorptiometry scan. A self-reported questionnaire was used for assessing sleep duration, which was categorized into ≤ 6, 7, 8, and ≥ 9 h per day.\u0000\u0000Results:\u0000Participants with low muscle mass were more prevalent in the longer sleep group, among men and women. Furthermore, in subgroup analysis, in which participants were classified into a young and middle-aged group, height-adjusted appendicular skeletal muscle mass was inversely related to sleep duration, regardless of sex. After adjusting for covariates, the probability of low muscle mass was increased in longer sleepers, and sleep duration and low muscle mass showed a positive dose-dependent correlation in men and women.\u0000\u0000Conclusion:\u0000In young and middle-aged adults, longer sleep duration may be related to decreased muscle mass, in both sexes.","PeriodicalId":12017,"journal":{"name":"European journal of general medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82817255","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Role of red blood cell distribution width and epicardial fat in atrial fibrillation after cardiopulmonary bypass 红细胞分布宽度和心外膜脂肪在体外循环术后房颤中的作用

European journal of general medicine Pub Date : 2018-01-09 DOI: 10.29333/EJGM/81804

K. Özbek, H. Katlandur, B. Arık, A. Kuzgun, M. Yıldız, A. Keser, H. Özdil

{"title":"Role of red blood cell distribution width and epicardial fat in atrial fibrillation after cardiopulmonary bypass","authors":"K. Özbek, H. Katlandur, B. Arık, A. Kuzgun, M. Yıldız, A. Keser, H. Özdil","doi":"10.29333/EJGM/81804","DOIUrl":"https://doi.org/10.29333/EJGM/81804","url":null,"abstract":"Objective:Postoperative atrial fibrillation (POAF) is a common complication after cardiac surgery, and it remains a challenge for cardiac surgeons despite advances in medicine. A number of studies have been performed to examine various parameters to predict which patients will develop POAF. The present study was performed to investigate the roles of epicardial adipose tissue (EAT) volume and red blood cell distribution width (RDW) as predictors of POAF.Methods:The medical records of 350 patients undergoing coronary artery bypass grafting in one or more vessels at the Tertiary Cardiac Center, Cardiovascular Surgery Department, Mevlana (Rumi) University Private Hospital (Konya, Turkey), were screened between December 2011 and May 2015. The study population consisted of 149 patients fulfilling the inclusion criteria and undergoing a preoperative evaluation by computed chest tomography. All patient demographics and laboratory parameters were obtained from medical records.Results:Age, postoperative RDW, and tomography variables, including the left atrial (LA) volume, LA diameters, and EAT volume, were significantly higher while the hemoglobin level and hematocrit were significantly lower in patients developing atrial fibrillation after cardiopulmonary bypass. A logistic multivariate regression analysis was performed on age, postoperative RDW, and tomography variables, including LA volume, LA diameters and EAT volume. Only age (OR 1.0731, 95% CI 1.012–1.138; p = 0.018) was an independent predictor of the development of POAF.Conclusions:Although the EAT volume was high in patients developing atrial fibrillation after surgery, age was the only significant predictor of POAF on multivariate analysis. Additional studies regarding the predictive roles of epicardial fat and RDW in POAF are needed.","PeriodicalId":12017,"journal":{"name":"European journal of general medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81196461","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

Candida species as potential nosocomial pathogens – A review 念珠菌作为潜在的医院病原菌——综述

European journal of general medicine Pub Date : 2018-01-09 DOI: 10.29333/EJGM/82346

V. Jahagirdar, M. Davane, Shrey C. Aradye, B. Nagoba

{"title":"Candida species as potential nosocomial pathogens – A review","authors":"V. Jahagirdar, M. Davane, Shrey C. Aradye, B. Nagoba","doi":"10.29333/EJGM/82346","DOIUrl":"https://doi.org/10.29333/EJGM/82346","url":null,"abstract":"The frequency of nosocomial fungal infections is being increased because of the advent of newer diagnostic and therapeutic techniques. Among various fungal pathogens, Candida spp. are the cause of substantial morbidity and mortality in hospitalized patients, especially among critically ill hospitalized patients. The frequency of non-ablicans spp. of Candida (NAC) causing nosocomial infections is increasing. The Candida infections are usually endogenous, however, the exogenous infections may also occur. The important predisposing factors leading to nosocomial candidiasis include treatment with broad spectrum antibiotics, immunosuppression, malignancy, surgical intervention, diabetes and prolonged hospitalization. Virulence factors like adherence to biotic and abiotic substances and production of hydrolytic enzymes play important role. Also the biofilm forming ability makes it more noxious. Nosocomial Candida infections are difficult to diagnose clinically and refractory to therapy. Therefore, rapid and accurate laboratory diagnosis is very important to provide appropriate antifungal treatment. This review is structured to know the key factors responsible for emergence of Candida spp. as important nosocomial pathogens. The available data suggests that the nosocomial infections caused by Candida spp. should be dealt through awareness and constant vigilance.","PeriodicalId":12017,"journal":{"name":"European journal of general medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82454700","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 24

Laryngeal & Lower lung field tuberculosis in pregnancy: A case report 妊娠期喉、下肺野结核1例

European journal of general medicine Pub Date : 2018-01-09 DOI: 10.29333/ejgm/82343

Patil Shital, M. Mirza

引用次数: 3