European journal of obstetrics, gynecology, and reproductive biology最新文献

{"title":"Evaluation of serum-based inflammatory and haematological markers in patients with endometriosis: A case–control study","authors":"Dilara Sarikaya Kurt ,&nbsp;Arife Akay ,&nbsp;Can Ozan Ulusoy ,&nbsp;Ahmet Kurt ,&nbsp;Gülşan Karabay ,&nbsp;Hüseyin Levent Keskin","doi":"10.1016/j.ejogrb.2025.114751","DOIUrl":"10.1016/j.ejogrb.2025.114751","url":null,"abstract":"<div><h3>Objective</h3><div>To assess the diagnostic value of serum-based inflammatory and haematological markers in women with endometriosis, and determine their relationship with disease severity, including lesion characteristics.</div></div><div><h3>Materials and methods</h3><div>This prospective study included 103 patients with endometriosis (aged 18–45 years) and 103 healthy controls. Serum C-reactive protein (CRP), albumin and complete blood counts were obtained pre-operatively, and inflammatory markers [neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio, neutrophil-to-platelet ratio (NPAR), CRP-to-albumin ratio (CAR), systemic inflammation index (SII), systemic inflammatory response index (SIRI) and pro-inflammatory index (PIV)] were calculated. Surgical evaluation (laparoscopy/laparotomy) provided histopathological confirmation of endometriosis. The 1996 revised American Society for Reproductive Medicine (rASRM) classification was used for staging. Statistical analyses used <em>t</em>-tests, Mann–Whitney <em>U</em>-tests, Chi-squared tests, Spearman’s correlation, and linear regression modelling. <em>p</em> &lt; 0.05 was considered to indicate significance.</div></div><div><h3>Results</h3><div>Compared with controls, patients with endometriosis had lower white blood cell (7.28 vs 8.43 × 10³/mm³; <em>p</em> &lt; 0.001), neutrophil (4.17 vs 5.09 × 10³/mm³; <em>p</em> &lt; 0.001) and CRP (2.45 vs 3.34 mg/l; <em>p</em> = 0.008) levels, but higher haemoglobin (12.8 vs 11.9 g/dl; <em>p</em> = 0.001) and haematocrit (40.5 % vs 38.1 %; <em>p</em> &lt; 0.001) levels. NPAR (1.38 vs 1.48; <em>p</em> &lt; 0.001), SII (539 vs 737; <em>p</em> &lt; 0.001), SIRI (1004 vs 1337; <em>p</em> &lt; 0.001), PIV (302 vs 422; <em>p</em> &lt; 0.001), CAR (0.061 vs 0.079; <em>p</em> = 0.008) and NLR (1.89 vs 2.44; <em>p</em> &lt; 0.001) were also significantly lower in patients with endometriosis. Postoperatively, NLR, SIRI, PIV and NPAR increased (<em>p</em> &lt; 0.05). Receiver operating characteristic curve analysis indicated moderate diagnostic performance for neutrophil percentage, NLR, SII, SIRI and PIV. On multi-variate analysis, bilaterality (<em>p</em> &lt; 0.001) and area of endometriomas (<em>p</em> = 0.020) correlated with rASRM score.</div></div><div><h3>Conclusion</h3><div>Serum inflammatory markers reflect systemic immune changes in endometriosis. Although they offer diagnostic insights, lesion bilaterality and size remain stronger predictors of disease severity. Larger, multi-centre studies are needed to refine cut-off values and optimize clinical application of these markers.</div></div>","PeriodicalId":11975,"journal":{"name":"European journal of obstetrics, gynecology, and reproductive biology","volume":"315 ","pages":"Article 114751"},"PeriodicalIF":1.9,"publicationDate":"2025-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145218235","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Changing trends in caesarean section rate in Ireland’s four largest maternity hospitals 2015–2021: which groups account for the rising caesarean section rate?","authors":"Charles Leahy ,&nbsp;Richard Greene ,&nbsp;Joye McKernan","doi":"10.1016/j.ejogrb.2025.114749","DOIUrl":"10.1016/j.ejogrb.2025.114749","url":null,"abstract":"<div><h3>Objectives</h3><div>To analyse the changing trends in Caesarean Section (CS) rates in Ireland’s four largest maternity hospitals between 2015 and 2021, utilizing the Robson Ten Group Classification System (TGCS).</div></div><div><h3>Methods</h3><div>This retrospective cohort study reviewed 221,098 deliveries from Cork University Maternity Hospital, The National Maternity Hospital, Rotunda Hospital, and The Coombe Hospital, spanning from 2015 to 2021. Data, collected by each individual hospital and submitted to the National Perinatal Audit Centre (NPEC), was combined into a single dataset. Statistical analysis was performed using linear regression to identify trends in CS rates and group contributions according to the TGCS. Pearson’s coefficient was employed to assess statistical significance.</div></div><div><h3>Results</h3><div>The overall CS rate significantly increased from 30.13 % in 2015 to 35.89 % in 2021 (p = 0.001). The primary drivers of this increase, accounting for over 90 % of the rise, were Group 2 and Group 5. Group 5 demonstrated a statistically significant increase in its Caesarean Section rate by 6.52 % (p = 0.001). Additionally, Group 10 (preterm birth) showed a significant increase in its Caesarean Section rate by 8 % (p = 0.046). Changes in Caesarean Section rates within other TGCS groups were not statistically significant.</div></div><div><h3>Conclusion</h3><div>The rising Caesarean Section rate in Ireland’s largest maternity hospitals is predominantly influenced by an increasing proportion of Group 2 and Group 5 overall and a higher Caesarean Section rate in Group 5. Targeted interventions aimed at reducing the overall CS rate should focus on these specific groups, potentially through optimizing induction practices, promoting shared decision-making regarding pre-labour Caesarean Section.</div></div>","PeriodicalId":11975,"journal":{"name":"European journal of obstetrics, gynecology, and reproductive biology","volume":"315 ","pages":"Article 114749"},"PeriodicalIF":1.9,"publicationDate":"2025-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145218234","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Implementation of enhanced recovery after surgery in gynaecologic oncology surgery: where should we start?","authors":"Koray Aslan ,&nbsp;Mükiye Kabakçi ,&nbsp;Tuba Zengin Aksel ,&nbsp;Menşure Kaya ,&nbsp;Funda Atalay","doi":"10.1016/j.ejogrb.2025.114752","DOIUrl":"10.1016/j.ejogrb.2025.114752","url":null,"abstract":"<div><h3>Purpose</h3><div>Compliance with elements of an enhanced recovery after surgery (ERAS) protocol is associated with better outcomes, including decreased length of hospital stay (LHS), but complete implementation is challenging. This study aimed to identify the role of individual ERAS elements on LHS to facilitate the implementation process.</div></div><div><h3>Methods</h3><div>This retrospective single-centre study included 233 women with gynaecological cancers who underwent surgery between 1 February 2021 and 31 July 2023. The first 120 consecutive patients after implementation of the ERAS programme were defined as the ERAS group, and the other patients were in the pre-ERAS group. The groups were compared in terms of LHS. Univariate and multi-variate analyses were used to define independent predictors of decreased LHS (≤5 days).</div></div><div><h3>Results</h3><div>The median LHS was 6 [interquartile range (IQR) 1–29] days for the ERAS group and 7 (IQR 3–23) days for the pre-ERAS group (<em>p</em> = 0.006). Avoidance of mechanical bowel preparation (<em>p</em> = 0.007), avoidance of surgical site drainage (<em>p</em> &lt; 0.001), removal of urinary drainage before postoperative day 3 (<em>p</em> = 0.02), regular diet initiation on postoperative day 0 (<em>p</em> = 0.02), and reduction in total opioid dose (<em>p</em> = 0.006) were significantly associated with LHS ≤ 5 days on univariate analysis. On multi-variate analysis, avoidance of surgical site drainage (<em>p</em> = 0.014), removal of urinary drainage before postoperative day 3 (<em>p</em> = 0.037), and reduction in total opioid dose (<em>p</em> = 0.045) remained significant for LHS ≤ 5 days.</div></div><div><h3>Conclusion</h3><div>Avoidance of surgical site drainage, removal of urinary drainage before postoperative day 3, and reduction in total opioid dose were found to be independent predictors of decreased LHS among ERAS items. Special consideration should be given to these items during the adoption of ERAS programmes.</div></div>","PeriodicalId":11975,"journal":{"name":"European journal of obstetrics, gynecology, and reproductive biology","volume":"315 ","pages":"Article 114752"},"PeriodicalIF":1.9,"publicationDate":"2025-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145218127","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Studying medicine – Does it influence the choice of contraceptive method?","authors":"Jan Pietruszka ,&nbsp;Maria Szewczyk ,&nbsp;Maciej Taraszkiewicz-Sirocki ,&nbsp;Maciej Walędziak ,&nbsp;Anna Różańska-Walędziak","doi":"10.1016/j.ejogrb.2025.114748","DOIUrl":"10.1016/j.ejogrb.2025.114748","url":null,"abstract":"<div><h3>Introduction</h3><div>Choosing a contraceptive method is an important aspect of sexual life. However, it can be a difficult decision due to insufficient knowledge about the physiology of the menstrual cycle and different methods of contraception. This raises the question of whether female medical students, who should have greater knowledge in this area, choose different contraceptive methods compared with non-medical students.</div></div><div><h3>Aim</h3><div>To examine contraceptive preferences in female students, and establish whether their field of study affects these preferences.</div></div><div><h3>Materials and methods</h3><div>This study included 414 female students: 189 from non-medical faculties, 122 from medical and dental faculties, and 103 from other medical faculties. The inclusion criteria for the study were: female gender; age ≥18 years; student status; informed consent to participate in the study; and completion of the questionnaire. Failure to meet any of the inclusion criteria resulted in exclusion from the study. Data were obtained through an anonymous survey created on the Google Forms platform, consisting of 16 questions. The questionnaire was distributed to potential female respondents via social media, and was open from 3 October 2023 to 3 December 2023.</div></div><div><h3>Results</h3><div>Barrier methods of contraception were used most commonly [264 respondents (63.78 %)], regardless of field of study, and the least commonly used method of contraception, chosen by only three respondents (0.72 %), was the hormone-free intrauterine device. When divided into three groups according to field of study, as in the survey, no significant correlation was found between field of study and preferred contraceptive method. However, when divided into two fields of study (combining medical and dental faculties with other medical faculties in one group), a significant correlation was found between field of study and the use of combined oral contraceptives containing oestrogens and progestins, which was more popular among medical students compared with non-medical students (33.3 % vs 24.3 %).</div></div><div><h3>Conclusions</h3><div>The influence of field of study on preferred contraceptive method is limited, possibly due to the fact that the majority of students, regardless of their field of study, obtain their knowledge about contraception from the internet – 48.9 % of medical students and 58.2 % of non-medical students. In comparison, 12.4 % of medical students but only 1.1 % of non-medical students reported obtaining their knowledge about contraception from lectures at university.</div></div>","PeriodicalId":11975,"journal":{"name":"European journal of obstetrics, gynecology, and reproductive biology","volume":"315 ","pages":"Article 114748"},"PeriodicalIF":1.9,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145250479","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Gestational weight gain and postpartum depressive symptoms in high-income women with low and late fertility","authors":"Vincenzo Zanardo ,&nbsp;Silvia Polver ,&nbsp;Beatrice Zanardo ,&nbsp;Francesca Volpe ,&nbsp;Tiziana Battistin ,&nbsp;Laura Ghiro ,&nbsp;Gianluca Straface","doi":"10.1016/j.ejogrb.2025.114746","DOIUrl":"10.1016/j.ejogrb.2025.114746","url":null,"abstract":"<div><h3>Objective</h3><div>This study aimed to investigate the relationship between GWG and postpartum depressive symptoms among high income women with ‘low and late fertility’, combined into a single category.</div></div><div><h3>Methods</h3><div>We examined the impact of low and late fertility on GWG, based on pre-pregnancy body mass index (BMI) categories, and postpartum depressive symptoms, tested by the Edinburgh Postnatal Depression Scale (EPDS), in a cohort of 2,561 low-risk puerperae, prior to discharge from the maternity ward of Abano Polyclinic, Abano Terme (Italy). Postpartum depressive symptoms were evaluated separately using EPDS cut-off thresholds of &gt; 9 and &gt; 12, as well as the Anhedonia, Anxiety, and Depression subscales.</div></div><div><h3>Results</h3><div>The women had a median age of 33.0 years (IQR: 30.0–37.0) and a parity of 1.00 (IQR: 1.00–2.00). A higher prevalence of pre-pregnancy underweight status (8.71 %) was observed compared to obesity (5.19 %). Additionally, 25.15 % of the participants had EPDS total scores &gt; 9, and 10.89 % had scores &gt; 12. Analysis revealed a significant overall association between pre-pregnancy BMI and GWG category (p &lt; 0.001), with 47.30 % classified as having adequate GWG, 24.25 % as inadequate, and 28.43 % as excessive. Finally, GWG was not associated with an increased risk of elevated EPDS total scores (&gt;9 or &gt; 12) or with higher scores on the Anhedonia, Depression, or Anxiety subscales.</div></div><div><h3>Conclusion</h3><div>In high-income women experiencing a late first pregnancy, the lack of association between abnormal GWG and postpartum psycho-emotional distress may be influenced by a higher prevalence of pre-pregnancy underweight status over obesity.</div></div>","PeriodicalId":11975,"journal":{"name":"European journal of obstetrics, gynecology, and reproductive biology","volume":"315 ","pages":"Article 114746"},"PeriodicalIF":1.9,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145270709","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Optimal surgical technique at cervical cerclage to prevent pregnancy loss, a systematic review","authors":"Matthew Vaughan ,&nbsp;Alexandra Emms ,&nbsp;Victoria Hodgetts Morton ,&nbsp;R.Katie Morris ,&nbsp;Fidan Israfil-Bayli ,&nbsp;Nicole Pilarski","doi":"10.1016/j.ejogrb.2025.114745","DOIUrl":"10.1016/j.ejogrb.2025.114745","url":null,"abstract":"<div><h3>Objective</h3><div>Cervical cerclage has been used for decades for prevention of preterm birth; no consensus regarding optimal surgical technique exists. This review assesses if Shirodkar’s technique (bladder dissection) is superior to McDonald’s (without dissection) with respect to pregnancy loss and maternal-fetal outcomes. A secondary aim is to assess potential benefits of double cerclage.</div></div><div><h3>Methods</h3><div>Systematic review was conducted, PROSPERO protocol (CRD42023472563). MEDLINE, Embase, CINAHL and Cochrane Library were searched. 1647 abstracts were screened, 22 studies met inclusion criteria. Bias was assessed using ROBINS-I and ROB2 and <em>meta</em>-analysis conducted using RevMan.</div></div><div><h3>Results</h3><div>Odds of pregnancy loss and birth &lt;37 weeks did not differ between dissection and no dissection groups (OR 0.95 [95 %CI 0.60–1.48], I²38%), (OR 0.86, [95 %CI 0.63–1.19], I²23%). Dissection prolonged pregnancy by 2 weeks (MD 2.29 [95 %CI 1.49–3.10], I²44%) and reduced birth &lt;32 weeks, (OR 0.43 [95 %CI 0.19–0.61], I²0%). Double cerclage reduced pregnancy loss, (OR 0.52 [95 %CI 0.28–0.98], I²29%), and birth &lt;28, &lt;32, &lt;34 weeks, however not at &lt;37 weeks, (OR 0.96, [95 %CI 0.64–1.45] I²35%).</div></div><div><h3>Conclusions</h3><div>No difference in odds of pregnancy loss was evident between surgical techniques, however dissection was associated with prolongation of pregnancy by 2 weeks and reduced odds of birth &lt;32 weeks. Double cerclage may provide additional benefits in prevention of preterm birth. Overall quality of evidence is low.<!--> <!-->Choice of technique should be informed by obstetric history, clinical examination, and clinician preference.</div></div>","PeriodicalId":11975,"journal":{"name":"European journal of obstetrics, gynecology, and reproductive biology","volume":"315 ","pages":"Article 114745"},"PeriodicalIF":1.9,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145269688","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Optimal surgical technique at cervical cerclage to prevent pregnancy loss, a systematic review","authors":"Matthew Vaughan ,&nbsp;Alexandra Emms ,&nbsp;Victoria Hodgetts Morton ,&nbsp;R.Katie Morris ,&nbsp;Fidan Israfil-Bayli ,&nbsp;Nicole Pilarski","doi":"10.1016/j.ejogrb.2025.114745","DOIUrl":"10.1016/j.ejogrb.2025.114745","url":null,"abstract":"<div><h3>Objective</h3><div>Cervical cerclage has been used for decades for prevention of preterm birth; no consensus regarding optimal surgical technique exists. This review assesses if Shirodkar’s technique (bladder dissection) is superior to McDonald’s (without dissection) with respect to pregnancy loss and maternal-fetal outcomes. A secondary aim is to assess potential benefits of double cerclage.</div></div><div><h3>Methods</h3><div>Systematic review was conducted, PROSPERO protocol (CRD42023472563). MEDLINE, Embase, CINAHL and Cochrane Library were searched. 1647 abstracts were screened, 22 studies met inclusion criteria. Bias was assessed using ROBINS-I and ROB2 and <em>meta</em>-analysis conducted using RevMan.</div></div><div><h3>Results</h3><div>Odds of pregnancy loss and birth &lt;37 weeks did not differ between dissection and no dissection groups (OR 0.95 [95 %CI 0.60–1.48], I²38%), (OR 0.86, [95 %CI 0.63–1.19], I²23%). Dissection prolonged pregnancy by 2 weeks (MD 2.29 [95 %CI 1.49–3.10], I²44%) and reduced birth &lt;32 weeks, (OR 0.43 [95 %CI 0.19–0.61], I²0%). Double cerclage reduced pregnancy loss, (OR 0.52 [95 %CI 0.28–0.98], I²29%), and birth &lt;28, &lt;32, &lt;34 weeks, however not at &lt;37 weeks, (OR 0.96, [95 %CI 0.64–1.45] I²35%).</div></div><div><h3>Conclusions</h3><div>No difference in odds of pregnancy loss was evident between surgical techniques, however dissection was associated with prolongation of pregnancy by 2 weeks and reduced odds of birth &lt;32 weeks. Double cerclage may provide additional benefits in prevention of preterm birth. Overall quality of evidence is low.<!--> <!-->Choice of technique should be informed by obstetric history, clinical examination, and clinician preference.</div></div>","PeriodicalId":11975,"journal":{"name":"European journal of obstetrics, gynecology, and reproductive biology","volume":"315 ","pages":"Article 114745"},"PeriodicalIF":1.9,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145269575","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of the need for in-vitro fertilization to conceive on pregnancy risks in women with the polycystic ovary syndrome. Evaluation of a population database and a matched cohort","authors":"Magdalena Peeva ,&nbsp;Ahmad Badeghiesh ,&nbsp;Haitham Baghlaf ,&nbsp;Michael H. Dahan","doi":"10.1016/j.ejogrb.2025.114742","DOIUrl":"10.1016/j.ejogrb.2025.114742","url":null,"abstract":"<div><h3>Objective</h3><div>To determine if conception by in-vitro fertilization (IVF) confers risk for adverse obstetric outcomes in women with polycystic ovary syndrome (PCOS).</div></div><div><h3>Design</h3><div>A retrospective population-based cohort study was conducted using data from the Healthcare Cost and Utilization Project Nationwide Inpatient Sample (2004–2014). Women who underwent IVF comprised the study group (n = 360), and the remaining women with PCOS comprised the reference group (n = 14,522). Logistic regression analyses were performed to explore associations between IVF, pregnancy, and delivery outcomes through the estimation of odds ratio (OR) and 95 % confidence intervals (CI). Sub-analyses performed examined outcomes in singleton pregnancies. A matched cohort analysis was conducted, comparing PCOS patients who underwent IVF and those who did not.</div></div><div><h3>Results</h3><div>Among all pregnant women with PCOS, IVF was associated with an increased risk for pre-term delivery (aOR 1.74, 95 %CI 1.05–2.88; p = 0.03), while controlling for confounders. IVF did not significantly increase the risk of other obstetrical complications. In singleton pregnancies, IVF was associated with a higher risk of preterm delivery (aOR2.12, 95 %CI 1.15–3.89; p = 0.016) and operative vaginal delivery (aOR 1.98, 95 %CI 1.03–3.8; p = 0.041). Without adjustment for multiple gestation, IVF was associated with an increased risk of preeclampsia (aOR2.05, 95 %CI1.17–3.61; p = 0.01), pre-term delivery (aOR2.67, 95 %CI 1.68–4.24 ;p &lt; 0.001), preterm premature rupture of membranes (aOR2.74, 95 %CI 1.15–6.54; p = 0.02), chorioamnionitis (aOR2.14 95 %CI 1.005–4.55; p = 0.048), and cesarean section (aOR1.69, 95 %CI 1.16–2.46; p = 0.007). In the matched cohort, women with PCOS who underwent IVF had a higher risk of placenta previa (aOR3.31 95 %CI 1.08–10.14; p = 0.05) and placental abruption (aOR3.04, 95 %CI 1.16–7.92; p = 0.02).</div></div><div><h3>Conclusion</h3><div>IVF appears minimally additive to the inherent risks associated with PCOS. Patients with PCOS who undergo IVF, are at an increased risk of placental abnormalities including placenta previa and placental abruption.</div></div>","PeriodicalId":11975,"journal":{"name":"European journal of obstetrics, gynecology, and reproductive biology","volume":"315 ","pages":"Article 114742"},"PeriodicalIF":1.9,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145205863","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Gestational weight gain and postpartum depressive symptoms in high-income women with low and late fertility","authors":"Vincenzo Zanardo ,&nbsp;Silvia Polver ,&nbsp;Beatrice Zanardo ,&nbsp;Francesca Volpe ,&nbsp;Tiziana Battistin ,&nbsp;Laura Ghiro ,&nbsp;Gianluca Straface","doi":"10.1016/j.ejogrb.2025.114746","DOIUrl":"10.1016/j.ejogrb.2025.114746","url":null,"abstract":"<div><h3>Objective</h3><div>This study aimed to investigate the relationship between GWG and postpartum depressive symptoms among high income women with ‘low and late fertility’, combined into a single category.</div></div><div><h3>Methods</h3><div>We examined the impact of low and late fertility on GWG, based on pre-pregnancy body mass index (BMI) categories, and postpartum depressive symptoms, tested by the Edinburgh Postnatal Depression Scale (EPDS), in a cohort of 2,561 low-risk puerperae, prior to discharge from the maternity ward of Abano Polyclinic, Abano Terme (Italy). Postpartum depressive symptoms were evaluated separately using EPDS cut-off thresholds of &gt; 9 and &gt; 12, as well as the Anhedonia, Anxiety, and Depression subscales.</div></div><div><h3>Results</h3><div>The women had a median age of 33.0 years (IQR: 30.0–37.0) and a parity of 1.00 (IQR: 1.00–2.00). A higher prevalence of pre-pregnancy underweight status (8.71 %) was observed compared to obesity (5.19 %). Additionally, 25.15 % of the participants had EPDS total scores &gt; 9, and 10.89 % had scores &gt; 12. Analysis revealed a significant overall association between pre-pregnancy BMI and GWG category (p &lt; 0.001), with 47.30 % classified as having adequate GWG, 24.25 % as inadequate, and 28.43 % as excessive. Finally, GWG was not associated with an increased risk of elevated EPDS total scores (&gt;9 or &gt; 12) or with higher scores on the Anhedonia, Depression, or Anxiety subscales.</div></div><div><h3>Conclusion</h3><div>In high-income women experiencing a late first pregnancy, the lack of association between abnormal GWG and postpartum psycho-emotional distress may be influenced by a higher prevalence of pre-pregnancy underweight status over obesity.</div></div>","PeriodicalId":11975,"journal":{"name":"European journal of obstetrics, gynecology, and reproductive biology","volume":"315 ","pages":"Article 114746"},"PeriodicalIF":1.9,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145269577","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dietl’s crisis from fibroid burden","authors":"Eva K. Welch,&nbsp;Katherine L. Dengler,&nbsp;Daniel D. Gruber","doi":"10.1016/j.ejogrb.2025.114744","DOIUrl":"10.1016/j.ejogrb.2025.114744","url":null,"abstract":"","PeriodicalId":11975,"journal":{"name":"European journal of obstetrics, gynecology, and reproductive biology","volume":"315 ","pages":"Article 114744"},"PeriodicalIF":1.9,"publicationDate":"2025-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145218183","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}