Elisabetta Manzoni , Chiara Dell’Utri , Daunia Verdi , Sara Parini , Daniela Lucidi , Gaya Spolverato
{"title":"Breaking barriers: Analysing the professional landscape for female gynaecological surgeons in Italy","authors":"Elisabetta Manzoni , Chiara Dell’Utri , Daunia Verdi , Sara Parini , Daniela Lucidi , Gaya Spolverato","doi":"10.1016/j.ejogrb.2024.10.039","DOIUrl":"10.1016/j.ejogrb.2024.10.039","url":null,"abstract":"<div><h3>Objective</h3><div>To examine the status of female gynaecological surgeons in Italy in terms of discriminatory practices and the availability of opportunities for improvement within the operating theatre.</div></div><div><h3>Methods</h3><div>This study is a subanalysis of a comprehensive 83-item questionnaire, administered to 3242 female surgeons across various specialties from 1 November to 31 December 2020. This study focuses specifically on 219 female gynaecological surgeons in order to explore their unique experiences and challenges in surgical practice.</div></div><div><h3>Main outcome measures</h3><div>Data concerning subjective satisfaction of respondents were collected. Satisfaction was evaluated using a five-point Likert scale. Data are presented using mean, median or frequency.</div></div><div><h3>Results</h3><div>This subanalysis included 207 respondents. Among the respondents, 47 % reported that they had children, while 31 % had decided not to have children for professional reasons. Nearly half of the respondents (42 %) were trainees. Despite a considerable workload (mean working week of 45 h), 96 % of the respondents reported spending less than half of their working time in the operating theatre. They performed a median of two operations per week, compared with five operations for their male counterparts. Despite challenges, 65 % expressed a commitment to their career path.</div></div><div><h3>Conclusions</h3><div>Efforts to address gender bias, promote work–life balance, and enhance female leadership representation are essential. These findings emphasize the need for systemic changes to create a supportive environment for female gynaecologists. Further research with broader sampling is warranted to fully understand and address these challenges.</div></div>","PeriodicalId":11975,"journal":{"name":"European journal of obstetrics, gynecology, and reproductive biology","volume":"303 ","pages":"Pages 282-287"},"PeriodicalIF":2.1,"publicationDate":"2024-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142603261","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sébastien Insubri , Laure Bernard , Chrystèle Rubod , Michel Cosson , Marine Lallemant , Géraldine Giraudet
{"title":"Long-term effectiveness of surgical removal of Essure® implants: A retrospective cohort study","authors":"Sébastien Insubri , Laure Bernard , Chrystèle Rubod , Michel Cosson , Marine Lallemant , Géraldine Giraudet","doi":"10.1016/j.ejogrb.2024.10.047","DOIUrl":"10.1016/j.ejogrb.2024.10.047","url":null,"abstract":"<div><h3>Study objective</h3><div>To assess symptom resolution and patient satisfaction following surgical explantation of Essure implants in the short and long term.</div></div><div><h3>Design</h3><div>Retrospective monocentric cohort study (Lille Regional University Hospital, France).</div></div><div><h3>Setting</h3><div>Essure is an implantable medical device for definitive sterilisation. Available from 2002, the Essure device has no longer been marketed since 2017. Following numerous reported side effects, the number of requests to withdraw Essure has steadily increased in recent years.</div></div><div><h3>Patients</h3><div>All women who underwent Essure removal between December 2016 and January 2020 to assess the benefits of surgery on these symptoms and patient satisfaction at 6 weeks and 6 months after the procedure.</div></div><div><h3>Interventions</h3><div>Removal of Essure implant with 4 types of surgery.</div></div><div><h3>Measurements</h3><div>The benefits of the surgery were assessed using data from the postoperative consultation 6 to 8 weeks after surgery and then from a telephone call 6 months after surgery.</div></div><div><h3>Main results</h3><div>86 patients were explanted during the study period. Surgery proved beneficial, with a complete reduction in symptoms at 6 months in 74 % of these patients. Many symptoms were relieved by surgery, with complete resolution of symptoms in 62 % of cases for muscle pain, in 69 % of cases for asthenia, in 82 % of cases for abdominal pain and 100 % of cases for menorrhagia. Patient satisfaction was high, with 97.3 % of patients willing to repeat the procedure and 95.95 % recommending it to a friend.</div></div><div><h3>Conclusion</h3><div>Removal of Essure implants in symptomatic patients appears to reduce all symptoms and improve quality of life in short and long term. Nevertheless, there are many symptoms associated with the insertion of Essure implants, and although surgery appears beneficial with good patient compliance, some adverse effects persist. It is therefore important to carry out a pre-operative etiological assessment and provide information on the risk of surgical failure.</div></div>","PeriodicalId":11975,"journal":{"name":"European journal of obstetrics, gynecology, and reproductive biology","volume":"303 ","pages":"Pages 212-217"},"PeriodicalIF":2.1,"publicationDate":"2024-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142567855","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Tess E.K. Cersonsky , Nina K. Ayala , Nailah S. Tucker , George R. Saade , Donald J. Dudley , Halit Pinar , Robert M. Silver , Uma M. Reddy , Adam K. Lewkowitz
{"title":"Adherence to recommended prenatal visit schedules and risk for stillbirth, according to probable cause of death","authors":"Tess E.K. Cersonsky , Nina K. Ayala , Nailah S. Tucker , George R. Saade , Donald J. Dudley , Halit Pinar , Robert M. Silver , Uma M. Reddy , Adam K. Lewkowitz","doi":"10.1016/j.ejogrb.2024.10.037","DOIUrl":"10.1016/j.ejogrb.2024.10.037","url":null,"abstract":"<div><h3>Objective</h3><div>Suboptimal prenatal care is linked to increased risk of stillbirth, but this association is not well-understood. The study objective was to evaluate the relationship between prenatal visit adherence and cause of death in stillbirths.</div></div><div><h3>Study Design</h3><div>This is a secondary analysis from the Stillbirth Collaborative Research Network of data with complete cause of death evaluation. Appropriateness of prenatal visit frequency was determined per American College of Obstetricians and Gynecologists/American Academy of Pediatrics (ACOG/AAP) recommendations and the novel Michigan Plan for Appropriately Tailored Healthcare in Pregnancy (MiPATH) guidelines. Multivariate regression controlled for differences between groups.</div></div><div><h3>Results</h3><div>Among 451 stillbirths included, 63.6% and 55.9% were non-adherent to ACOG/AAP and MiPATH recommendations, respectively. Non-adherent parturients according to the Michigan plan were more likely to have a stillbirth due to hypertensive disorders of pregnancy.</div></div><div><h3>Conclusion</h3><div>Non-adherence to prenatal visit guidelines is associated with higher risk of stillbirth due to hypertensive disorders of pregnancy.</div></div>","PeriodicalId":11975,"journal":{"name":"European journal of obstetrics, gynecology, and reproductive biology","volume":"303 ","pages":"Pages 159-164"},"PeriodicalIF":2.1,"publicationDate":"2024-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142564139","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Wenting Xu , Lili Zhu , Jiahui Wang , Lingli Shi , Xiuqin Tang , Qingli Chen , Lihong Wang
{"title":"Response to errors in the use of the FAERS database to assess the safety of Yasmin","authors":"Wenting Xu , Lili Zhu , Jiahui Wang , Lingli Shi , Xiuqin Tang , Qingli Chen , Lihong Wang","doi":"10.1016/j.ejogrb.2024.10.051","DOIUrl":"10.1016/j.ejogrb.2024.10.051","url":null,"abstract":"","PeriodicalId":11975,"journal":{"name":"European journal of obstetrics, gynecology, and reproductive biology","volume":"303 ","pages":"Pages 360-361"},"PeriodicalIF":2.1,"publicationDate":"2024-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142617538","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Indiamara Deggerone , Maria Laura Rodrigues Uggioni , Peterson Rech , Vitória Silveira , Tamy Colonetti , Luciane Bisognin Ceretta , Maria Inês Rosa , Antônio José Grande
{"title":"Fibromyalgia and sexual dysfunction in women: A systematic review and meta-analysis","authors":"Indiamara Deggerone , Maria Laura Rodrigues Uggioni , Peterson Rech , Vitória Silveira , Tamy Colonetti , Luciane Bisognin Ceretta , Maria Inês Rosa , Antônio José Grande","doi":"10.1016/j.ejogrb.2024.10.050","DOIUrl":"10.1016/j.ejogrb.2024.10.050","url":null,"abstract":"<div><h3>Introduction</h3><div>Fibromyalgia syndrome (FMS) is a chronic condition that associates pain, sleep disturbances, and cognitive changes. Recent evidence shows that sexual dysfunction is also associated with fibromyalgia, further affecting patients’ quality of life.</div></div><div><h3>Objective</h3><div>Our aim was to explore the association between FMS and sexual dysfunction (SD) in women.</div></div><div><h3>Methods</h3><div>A comprehensive search strategy was carried out, using the keywords “fibromyalgia” and “sexual dysfunction” and their synonyms. The databases used were MEDLINE, EMBASE, Scopus, Biomed Central, Web of Science, CINAHL, IBECS, LILACS, Congress Abstracts, and gray literature sources like Google Scholar. Studies published from January 1990 to August 2023 were considered, without imposing any language restrictions. The inclusion criteria involved studies that investigated individuals diagnosed with FMS and who suffered from sexual dysfunction, while studies that did not meet these criteria were excluded. The methodological quality of the included studies was assessed using the New Castle Ottawa tool. The results were presented in tables and forest graphs generated by the RevMan 5.4 software.</div></div><div><h3>Results</h3><div>27 studies were included, 10 of which were case-control and 17 were cross-sectional. These studies were published between 2005 and 2023, with participants aged between 18 and 81 years. Patients with FMS performed markedly worse than healthy controls in all domains of sexual dysfunction assessed. The methodological quality of the included studies was classified as moderate to high.</div></div><div><h3>Conclusion</h3><div>Compared to healthy women, the findings indicate a negative correlation between sexual dysfunction and fibromyalgia. These results underscore the significance of addressing sexual disturbances as a source of distress in the context of fibromyalgia syndrome. It becomes evident that incorporating psychological therapies that encompass emotional, physical, and sexual health could be a pivotal component in the comprehensive treatment of fibromyalgia syndrome.</div></div>","PeriodicalId":11975,"journal":{"name":"European journal of obstetrics, gynecology, and reproductive biology","volume":"303 ","pages":"Pages 171-179"},"PeriodicalIF":2.1,"publicationDate":"2024-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142564143","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pietro Santulli , Géraldine Giraudet , Jean-Philippe Estrade , Emilie Indersie , Sophie Morin , Céline Solignac , Elisangela Arbo , Horace Roman
{"title":"Impact of endometriosis on partners: Results from the French EndoVie survey","authors":"Pietro Santulli , Géraldine Giraudet , Jean-Philippe Estrade , Emilie Indersie , Sophie Morin , Céline Solignac , Elisangela Arbo , Horace Roman","doi":"10.1016/j.ejogrb.2024.10.040","DOIUrl":"10.1016/j.ejogrb.2024.10.040","url":null,"abstract":"<div><h3>Objectives</h3><div>To study the impact of endometriosis on women’s partners and evaluate the partners’ perceptions and experiences.</div></div><div><h3>Study design</h3><div>Between January 21 and 28, 2020, a prospective cross-sectional web-based survey was conducted among partners of women suffering from endometriosis. The investigated sample group (n = 100) was taken from a targeted population among the Ipsos Access panel that collects data from 235,171 French subjects. The online questionnaire aimed to assess the impact of endometriosis on partners’ well-being and daily life on a scale of 0 to 10 (where 0 represents very low impact and 10 represents very high impact).</div></div><div><h3>Results</h3><div>The survey included 92 men and 8 women. Most of them (78 %) were at least 45 years of age and had been in a relationship for over 13 years (63 %). For 75 %, the diagnosis of endometriosis was made after the relationship had begun. At the time of endometriosis diagnosis, the dominant partners’ feelings were concern, understanding, and compassion; however, 17 % also reported negative feelings. The average ratings for the impact of endometriosis on sexual relations and the couple’s life were 4.2 ± 3.2 out of 10 and 3.6 ± 2.8 out of 10, respectively. The psychological impact, impact on leisure, and impact on relationships with friends and family were less significant. Endometriosis was also found to impact partners’ emotions: 26 % reported that they did not often/very often understand the expectations of their partners when they underwent endometriosis-associated pain and 19 % reported feeling guilty about blaming their partner because of endometriosis.</div></div><div><h3>Conclusion</h3><div>This data provides new insights regarding the impact of endometriosis on partners of women suffering from the condition and highlights the importance of counselling in the management of endometriosis.</div></div>","PeriodicalId":11975,"journal":{"name":"European journal of obstetrics, gynecology, and reproductive biology","volume":"303 ","pages":"Pages 310-316"},"PeriodicalIF":2.1,"publicationDate":"2024-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142603270","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Azadeh Akbari Sene , Zahra Zandieh , Sadegh Amiri , FatemehSadat Amjadi , Mohammad Azimi Alamouty , Mandana Rashidi Meibodi , Arash Mohazzab , Roza Baharishargh , Behnaz Mohabatian
{"title":"Evaluation of the effect of an amniotic membrane derived bio-nano product (LifeCell) on human endometrial cells proliferation and gene expression: An in-vitro study","authors":"Azadeh Akbari Sene , Zahra Zandieh , Sadegh Amiri , FatemehSadat Amjadi , Mohammad Azimi Alamouty , Mandana Rashidi Meibodi , Arash Mohazzab , Roza Baharishargh , Behnaz Mohabatian","doi":"10.1016/j.ejogrb.2024.10.021","DOIUrl":"10.1016/j.ejogrb.2024.10.021","url":null,"abstract":"<div><h3>Objective</h3><div>Successful assisted reproductive technology (ART) requires a receptive endometrium with appropriate thickness and the presence of specific cytokines, chemokines, and growth factors. Despite advancements in ART, the success rates remain suboptimal, particularly in individuals with thin endometrium resistant to treatment. In this study, we evaluated the potential effects of LifeCell, a product of BioNano Technology, on the growth, development, and acceptance of endometrial cells.</div></div><div><h3>Study design</h3><div>We cultured endometrial cells in a defined medium with different concentrations of LifeCell and examined cell growth, development, and the expression of genes involved in endometrial receptivity.</div></div><div><h3>Results</h3><div>Co-culture of primary human endometrial cells with 5 % Life cell solution significantly stimulated the endometrial cell growth, development and receptivity genes expression. The expression levels of FGF2 and CSF in the 72 h co-cultured were significantly increased compared with other groups (P < 0.01). HOXA10 and LIF significantly increased in the 72 h co-cultured compared with 24 h co-cultured and control groups but had no significant level compared with 48 h cocultured. HOXA10 significantly increased in the 48 h cocultured compared with control group. IL-6 and Hb-EGF increased in the 48 h co-cultured compared to other groups but had no significant level. VEGF increased in the treated groups compared to control but had no significant level. The expression of OPN, unlike the other genes, decreased in the treated group compared to the control, which was not significant.</div></div><div><h3>Conclusions</h3><div>These findings suggest that LifeCell may be a potential option for patients with treatment-resistant thin endometrium in cases of infertility.</div></div>","PeriodicalId":11975,"journal":{"name":"European journal of obstetrics, gynecology, and reproductive biology","volume":"303 ","pages":"Pages 224-229"},"PeriodicalIF":2.1,"publicationDate":"2024-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142567851","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Remnants of right venous valve in utero and early postnatal life. Case report and literature review","authors":"Luigi Ferraro , Evelina Bertelli , Claudio Bonanno , Antonella Cromi , Fabio Ghezzi","doi":"10.1016/j.ejogrb.2024.10.020","DOIUrl":"10.1016/j.ejogrb.2024.10.020","url":null,"abstract":"<div><div>During fetal life the right valve of the sinus venosus directs oxygenated blood from the inferior vena cava to the left atrium through the foramen ovale, until the regression of the right valve which usually occurs within the 15th week of pregnancy. Incomplete regression of the right venous valve in varying degrees can lead to different types of remnants such as the Eustachian valve, the Chiari Network and Cor Triatriatum Dexter. Prenatal diagnosis of remnants of right venous valve has only rarely been reported in the literature. We present a case of prenatal diagnosis of Chiari Network associated with severe tricuspid regurgitation, further complicated by tachyarrhythmia and signs of fetal heart failure with the appearance of abundant pleural and ascitic effusion. A cesarean section was performed at 32 weeks. After 48 h of life, because of persistence of atrial flutter, an electrical cardioversion was performed. The physical examination 7 months after being discharged showed a normal growth, good condition and persistence of mild tricuspid regurgitation. We also reviewed the available evidence on persistent right venous valve diagnosed in utero or early postnatal life. In conclusion we believe that prenatal recognition is helpful in planning fetal surveillance identifying those newborns at risk of dyspnea, cyanosis or neonatal heart failure.</div></div>","PeriodicalId":11975,"journal":{"name":"European journal of obstetrics, gynecology, and reproductive biology","volume":"303 ","pages":"Pages 186-205"},"PeriodicalIF":2.1,"publicationDate":"2024-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142564125","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Juriy Wladimiroff , Sofia Tsiapakidou , Tahir Mahmood , Petr Velebil
{"title":"Caesarean section rates across Europe and its impact on specialist training in Obstetrics: A qualitative review by the Standing Committee of Hospital Visiting Programme for Training Recognition of the European Board and College of the Obstetrics and Gynaecology (EBCOG):","authors":"Juriy Wladimiroff , Sofia Tsiapakidou , Tahir Mahmood , Petr Velebil","doi":"10.1016/j.ejogrb.2024.10.044","DOIUrl":"10.1016/j.ejogrb.2024.10.044","url":null,"abstract":"<div><div>Information is presented from hospital visiting reports with focus on Caesarean section and vaginal instrumental delivery rates from training units in European countries during the period 1999 -2023. In a considerable number of countries training units were audited more than once, allowing assessment of trends in both obstetric interventions. There is a notable rise in Caesarean section rate in a number of European countries, with the highest rates in Poland (55.1%), Turkey (54.8%) and Greece (48.6%). Conversely Caesarean sections were low in France (19.3%) associated with a higher rate of instrumental vaginal delivery rates. Some countries like Germany and Poland have high variability in their rates, indicating fluctuations or regional differences over the years.</div><div>Vaginal instrumental delivery rates varied across countries having very low rates (Turkey with 1.0% and Poland with 1.2%) and others having relatively high rates (like Switzerland, France and Belgium). Germany and Belgium showed a balanced use of both Caesarean sections and vaginal instrumental deliveries but with considerable variability in both practices. Countries in Central Europe display marked differences in Caesarean section rate: Hungary 37.8%; Slovakia 34.5%, Czech Republic 27.5% and Slovenia 20.7%. Apart from Poland (1.2%), differences in vaginal instrumental delivery rate between these countries are relatively small with Hungary 2.7%, Slovakia 2.8% , Czech Republic 2.9% and Slovenia 2.9%. Low instrumental delivery rates have major effect on the quality of training for the trainees in their formative years. Having a limited experience in this area of clinical practice would influence their future clinical obstetric practice.</div></div>","PeriodicalId":11975,"journal":{"name":"European journal of obstetrics, gynecology, and reproductive biology","volume":"304 ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2024-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142703543","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}