European journal of obstetrics, gynecology, and reproductive biology最新文献

{"title":"IV iron supplementation, dosage, and timing in pregnancy: A single-institution review on a maternal transfusion reduction bundle","authors":"Alixandria F. Pfeiffer ,&nbsp;Nathalie Chang ,&nbsp;Oxana Zarudskaya ,&nbsp;Cece Cheng ,&nbsp;Michael D. Berkus ,&nbsp;Angela R. Boyd ,&nbsp;John J. Byrne ,&nbsp;Nora M. Doyle","doi":"10.1016/j.ejogrb.2025.03.045","DOIUrl":"10.1016/j.ejogrb.2025.03.045","url":null,"abstract":"<div><h3>Background</h3><div>Little is known about the effects of intravenous iron (IVFe) supplementation on maternal hemoglobin (Hb) by timing of infusion and dosage.</div></div><div><h3>Objective</h3><div>To identify the association of IVFe timing and dose on pre-delivery Hb.</div></div><div><h3>Study Design</h3><div>A retrospective cohort study of pregnant patients with iron deficiency anemia (IDA) who received iron sucrose (Venofer®) at our Level IV maternity care center following the implementation of a quality improvement (QI) transfusion reduction bundle from January 2020 to December 2023. The primary outcome was the association between IVFe timing and pre-delivery Hb. Secondary outcomes included the impact of IVFe dosage and infusion-to-delivery interval on Hb. Statistical analyses included paired t-tests, Mann-Whitney U tests, χ² tests, ANOVA, and post-hoc Tukey multiple comparisons (significance set at p &lt; 0.05).</div></div><div><h3>Results</h3><div>295 patients were included. Mean age, BMI, and ferritin were 26.6 ± 6.3 years, 28.1, and 7.2 ± 7.8 μg/L, respectively. Mean GA for IVFe administration was 34 weeks. Two patients required intrapartum/postpartum red blood cell transfusions. A greater mean Hb difference (2.5 g/dL vs 1.3 g/dL), was observed with IVFe at &lt;34 weeks compared to ≥34 weeks (p &lt; 0.001). Higher IVFe doses were associated with increased pre-delivery Hb levels (p = 0.002) and a longer infusion-to-delivery interval (p = 0.049). The strongest Hb improvement was seen with latency from ≥6–8 weeks with doses &gt;800 mg versus &lt;2 weeks at doses ≤ 800 mg (increase of 2.6 – 3.1 g/dL, p &lt; 0.0001).</div></div><div><h3>Conclusion</h3><div>Substantial benefit is seen when IVFe is given in the early third trimester, especially with ≥6 weeks of latency and doses ≥800 mg.</div></div>","PeriodicalId":11975,"journal":{"name":"European journal of obstetrics, gynecology, and reproductive biology","volume":"309 ","pages":"Pages 42-47"},"PeriodicalIF":2.1,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143644781","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An effective surgical approach to treat obese patients with gynecological disease using a subcutaneous abdominal wall-retraction device to perform low-pressure laparoscopy: A prospective, single-center study","authors":"Antonino Ditto ,&nbsp;Stefano Fucina ,&nbsp;Giulia Chiarello ,&nbsp;Giorgio Bogani ,&nbsp;Biagio Paolini ,&nbsp;Giuditta Fallabrino ,&nbsp;Umberto Leone Roberti Maggiore ,&nbsp;Francesco Raspagliesi","doi":"10.1016/j.ejogrb.2025.03.037","DOIUrl":"10.1016/j.ejogrb.2025.03.037","url":null,"abstract":"<div><h3>Objective</h3><div>Laparoscopic surgery of obese patients still represents a real challenge in clinical practice. High-pressure pneumoperitoneum and steep Trendelenburg position are the main anesthesiologic indications to laparotomic conversion. The aim of this prospective study was to assess effectiveness and safety of low-pressure laparoscopic (LPL) procedures using a subcutaneous abdominal wall-retraction (LaparoTenser ®).</div></div><div><h3>Materials and Methods</h3><div>We enrolled obese patients (BMI ≥ 30 kg/m²) with early-stage endometrial cancer, atypical endometrial hyperplasia and suspicious adnexal mass who were planned for laparoscopic surgery.</div></div><div><h3>Results</h3><div>A total of 33 patients were included in this study. The median age was 69 (range: 40–83), with a median BMI of 39 kg/m² (range: 33–48). At final pathologic report, 24 patients had endometrial cancer, 4 atypical endometrial hyperplasia, 2 had ovarian borderline tumors and 3 benign cysts. All LPL procedures were performed using the LaparoTenser ® device. Total hysterectomy plus bilateral salpingo-oophorectomy and sentinel node biopsy was the main procedure (69.7 % of cases). Laparotomy conversion rate due to inadequate visualization of the surgical field was 6.1 %. Postoperatively, no patient reported relevant abdominal discomfort caused by lifting of the abdominal wall. Grade &lt; 2 early complications rate was 21.1 %. One grade ≥ 3 complications was reported.</div></div><div><h3>Conclusions</h3><div>LPL technique using the LaparoTenser ® device is feasible and safe in morbidly obese patients. The wall-lifting device enables adequate viscera exposure creating a large intra-abdominal operative space avoiding the disadvantages of intraperitoneal high-pressure and CO₂ absorption.</div></div>","PeriodicalId":11975,"journal":{"name":"European journal of obstetrics, gynecology, and reproductive biology","volume":"309 ","pages":"Pages 55-60"},"PeriodicalIF":2.1,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143644782","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Does pelvic floor and abdominal muscle function and the synergy between these muscles change in young and older women with urinary incontinence?","authors":"Melda Başer Seçer ,&nbsp;Damla Korkmaz Dayican ,&nbsp;Ozge Celiker Tosun ,&nbsp;Onur Yavuz ,&nbsp;Sefa Kurt","doi":"10.1016/j.ejogrb.2025.03.032","DOIUrl":"10.1016/j.ejogrb.2025.03.032","url":null,"abstract":"<div><h3>Aim</h3><div>The aim of this study was to examine the synergistic relationship between the pelvic floor muscles (PFM) and abdominal muscles in older women with urinary incontinence (UI). Our secondary aim is to compare PFM and abdominal muscle functions and synergistic relationship according to incontinence type in younger and older women.</div></div><div><h3>Material and methods</h3><div>This cross-sectional study was conducted with 46 older and 31 younger women. Urogenital Distress Inventory (UDI-6) and Over Active Bladder-Validated 8 (OAB-V8) were used to evaluate the severity of participants’ urinary symptoms, and the Incontinence Impact Questionnaire (IIQ-7) was used to evaluate the quality of life related to the symptoms. PFM function was evaluated by superficial electromyography (EMG) and digital palpation; abdominal muscle function was evaluated by EMG.</div></div><div><h3>Results</h3><div>The average ages of the participants in the younger and old female groups were 49.74 ± 7.25 years and 74.87 ± 5.41 years, respectively. PFM endurance (p = 0.005), number of fast repetitions (p = 0.073) and work average value of the participants in the older women group were found to be lower than those in the younger women group (p = 0.002). In the group of older women with mixed incontinence (MUI), PFM endurance (p = 0.022), PFM (p = 0.002), Transversus abdominis (TrA) (p = 0.007), rectus abdominis (RA) (p = 0.015), internal oblique (IO)(p = 0.002) and external oblique (EO) abdominal muscles (p = 0.001) work average values ​​were significantly lower. In the younger women group with urge incontinence (UUI), the PFM work average value was higher than in the older women group (p = 0.021). During PFM contraction, a moderate positive correlation was found between PFM and RA (r = 0.498, p = 0.001), IO (r = 0.405, p = 0.006) and EO (r = 0.442, p = 0.002) in the older women group.</div></div><div><h3>Conclusion</h3><div>This study showed that older women with UI demonstrated reduced PFM endurance, fewer fast PFM contractions, and lower PFM and abdominal muscle activity compared to younger women with UI. A positive association was observed between the PFM and the RA, IO, and EO muscles specifically in older women with UI. Importantly, our findings indicate that both PFM and abdominal muscle function decline with age in women, irrespective of UI status, leading to a worsening of related symptoms. Consequently, we recommend the implementation of preventive physiotherapy and rehabilitation programs beginning at a young age to preserve and optimize PFM and abdominal muscle function in women.</div></div>","PeriodicalId":11975,"journal":{"name":"European journal of obstetrics, gynecology, and reproductive biology","volume":"309 ","pages":"Pages 89-96"},"PeriodicalIF":2.1,"publicationDate":"2025-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143644720","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prenatal manifestations of 3q29 deletion: A potential relationship with enlarged nuchal translucency","authors":"Xijing Liu ,&nbsp;Jiamin Wang ,&nbsp;Rui Hu ,&nbsp;Zhu Zhang ,&nbsp;Na Liao ,&nbsp;Like Xiao ,&nbsp;Junrong Guo ,&nbsp;Shanling Liu ,&nbsp;Ting Hu","doi":"10.1016/j.ejogrb.2025.03.016","DOIUrl":"10.1016/j.ejogrb.2025.03.016","url":null,"abstract":"<div><h3>Background</h3><div>The 3q29 deletion syndrome is characterized by neurodevelopmental and/or psychiatric manifestations after birth. Few cohort studies have been focused on prenatal manifestations of this syndrome.</div></div><div><h3>Objectives</h3><div>This study is aimed to reveal the prenatal manifestations of 3q29 deletion syndrome.</div></div><div><h3>Methods</h3><div>In this 5-year retrospective cohort study, gravidas with singleton pregnancies who underwent invasive prenatal diagnosis via single nucleotide polymorphism array for chromosomal abnormalities were included. First-trimester ultrasound screening was performed at 11⁺⁰––13⁺⁶ weeks’ gestation for all included gravidas, and detailed mid-trimester fetal anomaly scans were performed at 20⁺⁰––24⁺⁰ weeks’ gestation.</div></div><div><h3>Results</h3><div>The prevalence of 3q29 deletion was 0.24 per thousand (9/36,978) in the prenatal period. Approximately 77.78 % (7/9) fetuses with 3q29 deletion were observed with unseptate enlarged nuchal translucency (NT) without major heart defects. Except for one was inherited from the gravidas with mild intellectual disability, all the other eight were proven to be <em>de novo</em>. The incidence of 3q29 deletion in fetuses with enlarged NT was significantly higher than those without enlarged NT (<em>P</em> &lt; 0.001).</div></div><div><h3>Conclusion</h3><div>The 3q29 deletion was enriched in fetuses with enlarged NT. Enlarged NT was the most specific prenatal presentation for 3q29 deletions.</div></div>","PeriodicalId":11975,"journal":{"name":"European journal of obstetrics, gynecology, and reproductive biology","volume":"309 ","pages":"Pages 61-64"},"PeriodicalIF":2.1,"publicationDate":"2025-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143644814","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Knowledge mapping for prediction of spontaneous preterm birth","authors":"Hui Shen ,&nbsp;Lihe Zhang ,&nbsp;Han Bai,&nbsp;Lihong Wu,&nbsp;Liu Du,&nbsp;Hongning Xie","doi":"10.1016/j.ejogrb.2025.03.023","DOIUrl":"10.1016/j.ejogrb.2025.03.023","url":null,"abstract":"<div><h3>Introduction</h3><div>Preterm birth (PTB) before 37 weeks gestation, especially spontaneous premature birth (sPTB), poses significant global health challenges, with rising rates linked to advanced and multiple pregnancies. Despite efforts to understand the pathogenesis and related biomarkers of sPTB, accurate prediction is still difficult to achieve. Recent research in academic journals has focused on sPTB prediction, prompting our bibliometric analysis to understand the current situation and explore the new research direction.</div></div><div><h3>Methods</h3><div>We used keywords in the Web of Science Core Collection (WoSCC) to search for articles related to sPTB prediction from 2004 to 2023. Subsequently, we primarily employed three distinct software tools (VOSviewer, CiteSpace, and Python) for conducting this bibliometric analysis.</div></div><div><h3>Results</h3><div>Focusing on sPTB as the primary subject, a total of 647 papers have been published in 136 academic journals. There are the most publications from The United States (n = 245, 39.26 %), and the University of London contributed the most publications (n = 57, 8.81 %). The <em>American Journal of Obstetrics and Gynecology</em> is the most productive academic journal on sPTB prediction [n = 74, 11.44 %; impact factor (IF) = 8.7]. Through the co-occurrence and cluster analysis, we found that recent research has focused on is “pamg-1”, “uterocervical angle”, “twin pregnancy”, “quantitative ultrasound”, and “lactobacillus iners”.</div></div><div><h3>Conclusion</h3><div>We utilized bibliometric software to perform a comprehensive analysis of the literature concerning sPTB prediction. Broadly, the primary focus of future sPTB prediction lies in the application of novel ultrasound and biological markers, as well as in predicting sPTB in twin pregnancies.</div></div>","PeriodicalId":11975,"journal":{"name":"European journal of obstetrics, gynecology, and reproductive biology","volume":"309 ","pages":"Pages 79-88"},"PeriodicalIF":2.1,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143644718","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Outcome of obliterative versus reconstructive surgery for pelvic organ prolapse in women of advanced age − A propensity score analysis","authors":"Anna Padoa ,&nbsp;Roni Tomashev ,&nbsp;Matar Yekutiel ,&nbsp;Hadil Hassouna ,&nbsp;Liran Mendel ,&nbsp;Tal Fligelman","doi":"10.1016/j.ejogrb.2025.03.033","DOIUrl":"10.1016/j.ejogrb.2025.03.033","url":null,"abstract":"<div><h3>Objective</h3><div>Le Fort colpocleisis and reconstructive pelvic organ prolapse (POP) surgery in women aged ≥ 75 were compared. Evaluated outcomes were objective POP cure and long-term complications.</div></div><div><h3>Study Design</h3><div>We retrospectively identified patients aged &gt; 75 following POP surgery during 2008–2021. Data were retrieved from clinical files. Objective cure was defined as POP stage &lt; 2. Propensity score (PS) matching was used to balance background variables for outcomes of interest.</div></div><div><h3>Results</h3><div>108 women were identified. The PS-matched cohort for objective cure included 65 women and resulted in comparable cure rates: 18 (78.3%) vs 27 (64.3%) women, respectively (p = 0.375). Survival analysis demonstrated decreased rate of objective failure following Le Fort colpocleisis (HR = 0.52, 95% CI of [0.2138, 1.309], p = 0.20).</div><div>In the initial cohort, obliterative surgery resulted in more postoperative constipation. A PS model matched for constipation included 55 women and resulted in a trend to more constipation following Le Fort colpocleisis: 9 (40.9%) women vs 4 (13.8%) women, respectively (p = 0.06, SMD = 0.639).</div></div><div><h3>Conclusion</h3><div>Reconstructive POP surgery and Le Fort colpocleisis are equally effective in women of advanced age. POP recurrence may appear earlier following reconstructive surgery. Obliterative surgery may be related to more postoperative constipation.</div></div>","PeriodicalId":11975,"journal":{"name":"European journal of obstetrics, gynecology, and reproductive biology","volume":"309 ","pages":"Pages 27-33"},"PeriodicalIF":2.1,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143637599","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"What went wrong?: Patient reasons for nonattendance at Women’s health physiotherapy","authors":"Phil Reed ,&nbsp;Emily Sharples-Carter ,&nbsp;Emily Syder ,&nbsp;Aemaan Javaid ,&nbsp;Hannalee Lewis ,&nbsp;Catherine M. Havard-Thomas ,&nbsp;Simon Emery ,&nbsp;Lisa A. Osborne","doi":"10.1016/j.ejogrb.2025.03.024","DOIUrl":"10.1016/j.ejogrb.2025.03.024","url":null,"abstract":"<div><div>Nonattendance at women’s health physiotherapy sessions involves considerable cost in time and resources. Uncovering factors associated with nonattendance is one priority, and the current research aimed to enhance understanding of this issue. In each of two studies, women referred for women’s health physiotherapy were interviewed. Study 1 (<em>N</em> = 80) compared participants who did and did not attend their appointment, and Study 2 (<em>N</em> = 61) compared reasons for nonattendance given by women with pelvic-floor muscle dysfunction and pelvic girdle pain. The results corroborated several key issues associated with nonattendance noted in previous reports, such as problems in the administration of appointments. Results further suggested attention to the information given by healthcare professionals at the time of referral may help remove some barriers to attendance. The issue of transport to appointments was raised, and developing links to affordable and reliable systems is critical, including development of dedicated transport systems. Finally, the psychological aspects of patients who do not attend appeared to differ and addressing these issues could form part of their treatment. Although each recommendation does involve cost, the savings from reduction in nonattendance may outweigh any initial costs of set up.</div></div>","PeriodicalId":11975,"journal":{"name":"European journal of obstetrics, gynecology, and reproductive biology","volume":"309 ","pages":"Pages 34-41"},"PeriodicalIF":2.1,"publicationDate":"2025-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143642713","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Residual placental blood volume after cesarean section: A scoping review","authors":"Sara Maler ,&nbsp;Kari Axelsson ,&nbsp;Deborah Utjés ,&nbsp;Thomas Abrahamsson ,&nbsp;Jenny Svedenkrans ,&nbsp;Li Thies-Lagergren ,&nbsp;Ola Andersson ,&nbsp;Anna Sand","doi":"10.1016/j.ejogrb.2025.03.021","DOIUrl":"10.1016/j.ejogrb.2025.03.021","url":null,"abstract":"<div><div>The overall aim of this scoping review was to map the existing literature on residual placental blood volume in cesarean sections as an indirect measure of placental transfusion. Multiple databases including Pubmed, Cochrane, Embase and Web of Science were searched for relevant studies published between 1972 and 2023. All studies on cesarean sections with term pregnancies and information on residual placental blood volume were included. The PRISMA checklist was used for guiding the writing of this report. The literature search resulted in 31 studies including 8337 neonates born by cesarean section. Only four studies specifically explored cord clamping time in cesarean section and following residual placental blood volume. All except one, showed a significant association between delayed cord clamping and decreased residual placental blood volume, indicating an increased placental transfusion to the infant. No difference was found between emergency and elective cesarean section. Inconclusive results appeared regarding association between placental weight, foetal weight, gravitation, uterotonics and residual placental blood volume. Delayed cord clamping time in cesarean section seems to be associated with a decreased residual placental blood volume indicating an increased transfusion to the infant. Due to the limited evidence revealing placental transfusion in cesarean section, further studies are needed to investigate the physiology of placental transfusion and to identify the optimal time of cord clamping at cesarean section.</div></div>","PeriodicalId":11975,"journal":{"name":"European journal of obstetrics, gynecology, and reproductive biology","volume":"309 ","pages":"Pages 65-72"},"PeriodicalIF":2.1,"publicationDate":"2025-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143644813","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Perineal body and anal sphincter biometrics and stiffness using elastography during labor: a feasibility study","authors":"Marine Lallemant ,&nbsp;Tiguida Kadiaké ,&nbsp;Arnaud Lejeune ,&nbsp;Michel Cosson ,&nbsp;Jérôme Chambert ,&nbsp;Emmanuelle Jacquet ,&nbsp;Nicolas Mottet","doi":"10.1016/j.ejogrb.2025.03.034","DOIUrl":"10.1016/j.ejogrb.2025.03.034","url":null,"abstract":"<div><h3>Objectives</h3><div>The study aimed to evaluate the biometrics and stiffness of the perineal body and anal sphincter using 2D-mode ultrasound and shear wave elastography (SWE) during labor and to assess their association with perineal tears.</div></div><div><h3>Methods</h3><div>A prospective observational study was conducted on pregnant women. The perineal body (PB), the external anal sphincter (EAS), the internal anal sphincter (IAS) and the anal mucosa (AM) biometrics and stiffness were measured during labor using a transperineal 2D-mode ultrasound and shear wave elastography (SWE), respectively, at rest and during Valsalva maneuvers.</div></div><div><h3>Results</h3><div>Among the 10 women who underwent a vaginal delivery, 6 (60.0 %) perineal tears occurred. All were first degree perineal tears. Before expulsive efforts, the PB area at rest was statistically higher in women with perineal tears (1.0 ± 0.1 cm2 vs 0.3 ± 0.1 cm2, p &lt; 0.01). The perineal body length, height and area seemed to decrease between the onset of labor and the beginning of expulsive efforts. The PB Youngs’ modulus at rest at the onset of labor or before expulsive efforts were 11.9 ± 3.6 kPa and 25.7 ± 18.9 kPa, respectively. The PB elastic modulus at rest and at the onset of labor (11.3 ± 4.1 vs 12.9 ± 2.9 kPa, p = 0.6) or before expulsive efforts (18.0 ± 15.9 vs 37.4 ± 18.6 kPa, p = 0.1) tended to be higher in women with a perineal tear at delivery, but it was not statistically significant.</div></div><div><h3>Conclusion</h3><div>In vivo assessment of both the perineal body and anal sphincter biometrics and stiffness during labor in women is feasible. The perineal body area during labor could be a predictive factor for perineal tears, suggesting a potential link between its stiffness and tear risk.</div></div><div><h3>Trial registration</h3><div>The study was registered on <span><span>https://clinicaltrials.gov</span><svg><path></path></svg></span> (NCT05556304): <span><span>https://classic.clinicaltrials.gov/ct2/show/NCT05556304</span><svg><path></path></svg></span>.</div></div>","PeriodicalId":11975,"journal":{"name":"European journal of obstetrics, gynecology, and reproductive biology","volume":"309 ","pages":"Pages 48-54"},"PeriodicalIF":2.1,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143644719","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Update on the challenges of labor and delivery","authors":"Tullio Ghi,&nbsp;Andrea Dall’Asta","doi":"10.1016/j.ejogrb.2025.02.061","DOIUrl":"10.1016/j.ejogrb.2025.02.061","url":null,"abstract":"","PeriodicalId":11975,"journal":{"name":"European journal of obstetrics, gynecology, and reproductive biology","volume":"308 ","pages":"Page 240"},"PeriodicalIF":2.1,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143619649","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}