European journal of obstetrics, gynecology, and reproductive biology最新文献

{"title":"Retraction notice to “Evaluation of the effectiveness of low-dose aspirin and omega 3 in treatment of asymmetrically intrauterine growth restriction: A randomized clinical trial” [Eur. J. Obstet. Gynecol. Reprod. Biol. 210 (2017) 231-235]","authors":"Mohammed K. Ali , Maggy E. Amin , Ahmed F. Amin , Diaa Eldeen M. Abd El Aal","doi":"10.1016/j.ejogrb.2025.114035","DOIUrl":"10.1016/j.ejogrb.2025.114035","url":null,"abstract":"","PeriodicalId":11975,"journal":{"name":"European journal of obstetrics, gynecology, and reproductive biology","volume":"312 ","pages":"Article 114035"},"PeriodicalIF":2.1,"publicationDate":"2025-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144170094","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Outcomes and cost-effectiveness of vNOTES vs conventional laparoscopic ovarian cystectomy for ovarian teratoma (dermoid cysts): A comparison of two minimal access routes of surgery","authors":"Wai Yoong,&nbsp;Zachary Penny ,&nbsp;Joachim Ho ,&nbsp;Olushola Ariyo,&nbsp;Sarah Wylie","doi":"10.1016/j.ejogrb.2025.114087","DOIUrl":"10.1016/j.ejogrb.2025.114087","url":null,"abstract":"<div><h3>Objective</h3><div>Laparoscopic ovarian cystectomy is the benchmark surgical treatment for ovarian teratoma but vNOTES is emerging as an alternative with avoidance of abdominal scars, less pain and more rapid recovery. This study aimed to compare outcome data and expenditure for two minimally invasive routes in the surgical management of ovarian teratoma.</div></div><div><h3>Study design</h3><div>Case control study of vNOTES <em>vs</em> laparoscopic ovarian cystectomy (<em>n</em> = 21 in each group).</div></div><div><h3>Methods</h3><div>Data collected included age, BMI, teratoma size, duration of surgery, estimated blood loss, length of stay and <em>peri</em>-operative complications. Expenditure for the procedures were calculated using unit costs verified with NHS England Cost Collection website.</div></div><div><h3>Results</h3><div>Mean age (38.42 <em>vs</em> 39.80 yrs), BMI (29.38 <em>vs</em> 27.90 kg/m³), parity (0.91 <em>vs</em> 1.20), EBL (110.10 <em>vs</em> 93.60 mL) and teratoma size (7.60 <em>vs</em> 7.20 cm) were statistically similar but vNOTES patients had shorter mean theatre duration (48.33 <em>vs</em> 92.10 mins), length of stay (3.94 <em>vs</em> 13.2 hrs) and VAS at 24 h (1.90 <em>vs</em> 4.00) with less requiring opioids (14.3 <em>vs</em> 33.3 %) (all <em>p</em> &lt; 0.05). vNOTES patients returned to normal daily activity quicker (8.0 <em>vs</em> 20.0 days) and had less intra-peritoneal spillage (0 <em>vs</em> 33 %) (both <em>p</em> &lt; 0.05). Expenditure for laparoscopic ovarian cystectomy is approximately 1.5 times that of vNOTES cases (£3303.76 <em>vs</em> £2147.76) due to longer theatre and recovery bed occupancy, need for additional assistant and use of endoscopic bags.</div></div><div><h3>Conclusion</h3><div>Shorter theatre duration and length of stay, better cosmesis, less pain and rapid recovery, allied with lower cost support the adoption of vNOTES as a viable option for minimally invasive adnexectomy for ovarian teratoma.</div></div>","PeriodicalId":11975,"journal":{"name":"European journal of obstetrics, gynecology, and reproductive biology","volume":"312 ","pages":"Article 114087"},"PeriodicalIF":2.1,"publicationDate":"2025-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144170092","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ferric carboxymaltose for iron deficiency in twin pregnancies: A single center 10-year retrospective longitudinal pre-post study","authors":"Anna A. Wawer ,&nbsp;Anthea Lambrakis ,&nbsp;Kim White ,&nbsp;Romi Sinha ,&nbsp;Gustaaf Dekker ,&nbsp;Bernd Froessler","doi":"10.1016/j.ejogrb.2025.114084","DOIUrl":"10.1016/j.ejogrb.2025.114084","url":null,"abstract":"<div><h3>Background</h3><div>Iron demand is almost double and anemia prevalence four times higher in twin pregnancy. There is limited information on the impact of antenatal intravenous iron (IVI) on maternal hemoglobin in women pregnant with twins.</div></div><div><h3>Objective</h3><div>The main objective was to assess the safety and efficacy of IVI in twin pregnancy. The secondary objective was to analyze the impact of intraoperative cell salvage as an additional Patient Blood Management (PBM) tool.</div></div><div><h3>Study Design</h3><div>Single center retrospective longitudinal pre-post study of all women, pregnant with twins, receiving intravenous Ferric Carboxymaltose (FCM) between 2013 and 2023.</div></div><div><h3>Results</h3><div>One hundred nineteen women were included in the analysis. Mean ferritin values prior infusion was 10.9, 12.9, 15.3, and 15.4 µg/L in the severe, moderate, mild and no anemia group respectively. Post infusion mean hemoglobin increased by 21.6 g/L, 13.4 g/L, 11.0 g/L, and 6.8 g/L in the respective groups. No serious adverse events were reported. Forty-four (36.9 %) suffered a postpartum hemorrhage (mean blood loss 1278 ml). Seventeen women received red blood cells. Five had an allogeneic transfusion whereas twelve had cell salvaged autologous re-infusion. Post IVI hemoglobin was negatively correlated with length of stay.</div></div><div><h3>Conclusions</h3><div>We observed a significant increase in antenatal hemoglobin and restored iron status in twin pregnancies in response to IVI. Low allogeneic red blood cell transfusion rates were achieved by combining iron infusion with the utilization of cell salvage technology and autologous reinfusion as part of our Obstetric PBM approach.</div></div>","PeriodicalId":11975,"journal":{"name":"European journal of obstetrics, gynecology, and reproductive biology","volume":"312 ","pages":"Article 114084"},"PeriodicalIF":2.1,"publicationDate":"2025-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144177578","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Erratum to “Investigation of amino acid profile alterations in maternal serum for early diagnosis of anembryonic pregnancy with high performance liquid chromatography-mass spectrometry” [294 (2024) 49–54]","authors":"Min Zhang ,&nbsp;XiaoLin Lu ,&nbsp;LaLa Mi ,&nbsp;MeiYan Song ,&nbsp;Li Wang ,&nbsp;XiaoYan Wang","doi":"10.1016/j.ejogrb.2025.114063","DOIUrl":"10.1016/j.ejogrb.2025.114063","url":null,"abstract":"","PeriodicalId":11975,"journal":{"name":"European journal of obstetrics, gynecology, and reproductive biology","volume":"312 ","pages":"Article 114063"},"PeriodicalIF":2.1,"publicationDate":"2025-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144138391","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A scoping review of decision aids for pregnant women around childbirth: Do they improve decision quality, processes, and outcomes?","authors":"Truc Phuong Nguyen ,&nbsp;Ana Pilar Betrán ,&nbsp;Maria Regina Torloni ,&nbsp;Nils Chaillet ,&nbsp;Alexandre Dumont","doi":"10.1016/j.ejogrb.2025.114085","DOIUrl":"10.1016/j.ejogrb.2025.114085","url":null,"abstract":"<div><h3>Background</h3><div>Meaningful engagement of women in childbirth decisions is a growing priority in maternity care. Decision aids are tools designed to improve decision quality, decision-making processes quality, care behaviours, and health outcomes (quadruple aim).</div></div><div><h3>Objective</h3><div>To map quantitative studies evaluating the effects of decision aids for women making decisions around childbirth.</div></div><div><h3>Methods</h3><div>We searched MEDLINE, Cochrane DSR and CENTRAL, CINAHL, and EMBASE (January 1975–April 2025) for reviews, randomized controlled trials and controlled before-and-after studies that assessed the effect of decision aids for childbirth decisions.</div></div><div><h3>Results</h3><div>28 studies (11 reviews, 17 primary studies) met selection criteria. Most involved high-risk pregnant women and showed that decision aid improved the quality of decision and decision-making process. Positive impacts on care behaviour and health outcomes were more evident when decision aids were combined with other components and required discussions with healthcare providers.</div></div><div><h3>Discussion</h3><div>Although limited, evidence suggests decision aids are more effective when women are prepared to use the tool and healthcare providers are actively involved. The review identified gaps in research targeting low-risk women in low- and middle-income countries and assessing women’s value and preferences for shared decision-making.</div></div><div><h3>Conclusions</h3><div>Decision aids around childbirth have the potential to meet women’s needs in decision-making, appropriate use of care and perinatal health outcomes especially when they are prepared to use the tool and supported by healthcare providers. Future research should evaluate all four aim objectives to strengthen the evidence on the benefits of decision aids, especially for low-risk population and in low- and middle-income countries.</div></div>","PeriodicalId":11975,"journal":{"name":"European journal of obstetrics, gynecology, and reproductive biology","volume":"312 ","pages":"Article 114085"},"PeriodicalIF":2.1,"publicationDate":"2025-05-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144154790","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Changes in fatigue, health-related fitness, sleep quality, mental health, gastrointestinal complaints and sexual function after a multimodal supervised therapeutic exercise program in women with endometriosis unresponsive to conventional therapy: a secondary analysis of a randomized controlled trial","authors":"María del Mar Salinas-Asensio ,&nbsp;Francisco Álvarez-Salvago ,&nbsp;Antonio Mundo-López ,&nbsp;Olga Ocón-Hernández ,&nbsp;Mario Lozano-Lozano ,&nbsp;María López-Garzón ,&nbsp;Paula Postigo-Martín ,&nbsp;Manuel Arroyo-Morales ,&nbsp;Ángel Rodríguez-Ruiz ,&nbsp;Carolina Fernández-Lao ,&nbsp;Francisco Artacho-Cordón","doi":"10.1016/j.ejogrb.2025.114083","DOIUrl":"10.1016/j.ejogrb.2025.114083","url":null,"abstract":"<div><h3>Objective</h3><div>To explore the impact of ‘Physio-EndEA’, a multimodal 9-week supervised exercise intervention, on fatigue, health-related physical fitness, sleep quality, mental health, gastrointestinal complaints, and sexual function in women with endometriosis unresponsive to conventional therapy.</div></div><div><h3>Methods</h3><div>This randomized controlled trial included 31 patients randomly allocated to the ‘Physio-EndEA’ group (n = 16) or the control group (n = 15). The primary outcome, fatigue, was evaluated using the Piper Fatigue Scale (PFS). Secondary outcomes included health-related physical fitness [lumbar strength (back dynamometer), lumbar flexibility (Schöber test), body balance (Flamingo test) and cardiorespiratory fitness (6-minute walking test, 6MWT)], sleep quality (Pittsburgh Sleep Quality Index, PSQI), anxiety and depression (Hospital Anxiety and Depression Scale, HADS), digestive complaints (Gastrointestinal quality of life index, GIQLI), and sexual function (Female sexual function index, FSFI). Outcomes were measured at baseline, post-intervention, and at one year. Statistical (between-group analyses of covariance) and clinical effects were analyzed by intention-to-treat. The study was registered with <span><span>ClinicalTrials.gov</span><svg><path></path></svg></span> #NCT03979183.</div></div><div><h3>Results</h3><div>After the intervention and at 1 year, the ‘Physio-EndEA’ group showed significantly improved fatigue compared with the control group, with large size effects (d &gt; 0.80). Post-intervention improvements were also observed in the intervention group for lumbar strength, cardiorespiratory fitness, anxiety, depression, and digestive complaint scores. Improvements in cardiorespiratory fitness, anxiety and digestive complaints were maintained at the 1-year follow-up.</div></div><div><h3>Conclusions</h3><div>A 9-week supervised multimodal therapeutic exercise program is effective in ameliorating a broad range of endometriosis-related impairments, suggesting that ‘Physio-EndEA’ is a promising strategy for reducing symptom burden in women with endometriosis unresponsive to conventional treatment.</div></div>","PeriodicalId":11975,"journal":{"name":"European journal of obstetrics, gynecology, and reproductive biology","volume":"312 ","pages":"Article 114083"},"PeriodicalIF":2.1,"publicationDate":"2025-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144154791","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lack of originality of technique in preprint “Intracavitary-Electrohysterogram: Novel technique for assessing uterine peristalsis and electrophysiology in non-pregnant women” and intentionally omitted references to past work","authors":"Vasilios Tanos,&nbsp;Julius Georgiou","doi":"10.1016/j.ejogrb.2025.114076","DOIUrl":"10.1016/j.ejogrb.2025.114076","url":null,"abstract":"","PeriodicalId":11975,"journal":{"name":"European journal of obstetrics, gynecology, and reproductive biology","volume":"312 ","pages":"Article 114076"},"PeriodicalIF":2.1,"publicationDate":"2025-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144177579","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Management of pregnancy of unknown location","authors":"Yue Lin,&nbsp;Yingxi Wang,&nbsp;Ying Huang,&nbsp;Lina Wang,&nbsp;Rong Li,&nbsp;Xiumei Zhen","doi":"10.1016/j.ejogrb.2025.114047","DOIUrl":"10.1016/j.ejogrb.2025.114047","url":null,"abstract":"<div><div>Pregnancy of unknown location (PUL) refers to a condition in which a woman has a positive pregnancy test without definite sign of pregnancy on transvaginal ultrasound. The main concern about PUL could be lethal if a patient isn’t diagnosed with ectopic pregnancy timely. Therefore, triaging women with high risk is a primary goal in the management of women with PUL. On the premise of ensuring safety, many efforts have been made to offer both efficient and satisfactory treatment for women with PUL in recent years. This review provides an overview of factors that should be considered during the diagnosis and treatment progress of PULs. Mathematical prediction models, incorporating more than serum human chorionic gonadotropin and progesterone levels, exhibit satisfying performance in triaging women with PUL. As assisted reproductive technologies advance by leaps and bounds, a new indicative of estimating the intervention risk occurs in the management of PULs following assisted reproductive technologies. In the meanwhile, patient-centered care, an important principle in clinical practice, and other potential biomarkers deserve our attention. Hopefully, this review could offer some potential research avenues and trigger future advancements in the management of PUL.</div></div>","PeriodicalId":11975,"journal":{"name":"European journal of obstetrics, gynecology, and reproductive biology","volume":"312 ","pages":"Article 114047"},"PeriodicalIF":2.1,"publicationDate":"2025-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144138392","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Increased risk of cardiovascular disease in women with endometriosis: A systematic review and meta-analysis","authors":"Muhammad Saad ,&nbsp;Ifrah Ansari ,&nbsp;Zainab Siddiqua Ibrahim ,&nbsp;Ruqiat Masooma Batool ,&nbsp;Syed Ibad Ahsan ,&nbsp;Muhammad Sameer Arshad ,&nbsp;Peter Collins ,&nbsp;Raheel Ahmed","doi":"10.1016/j.ejogrb.2025.114081","DOIUrl":"10.1016/j.ejogrb.2025.114081","url":null,"abstract":"<div><h3>Background</h3><div>The association between endometriosis and cardiovascular disease remains poorly understood. This study conducted a meta-analysis to evaluate the risk of adverse cardiovascular outcomes in women with endometriosis compared to those without the condition.</div></div><div><h3>Methods</h3><div>A comprehensive search of online databases was performed up to November 2024 to identify studies comparing adverse cardiovascular outcomes in women with and without endometriosis. A random-effects model was employed for the meta-analysis to calculate hazard ratios (HRs) with 95% confidence intervals (CIs).</div></div><div><h3>Results</h3><div>The meta-analysis included seven studies encompassing a total of 1,407,875 participants. Women with endometriosis demonstrated a significantly increased risk of cerebrovascular disease (HR: 1.19, 95 % CI: 1.13–1.24, p &lt; 0.00001) and ischemic heart disease (HR: 1.35, 95 % CI: 1.32–1.39, p &lt; 0.00001). Additionally, the risk of major adverse cardiovascular events (HR: 1.15, 95 % CI: 1.13–1.19, p &lt; 0.00001) and arrhythmias (HR: 1.21, 95 % CI: 1.17–1.25, p &lt; 0.00001) was significantly elevated. However, no significant associations were observed for heart failure or all-cause mortality.</div></div><div><h3>Conclusion</h3><div>This meta-analysis indicates that women with endometriosis are at heightened risk for several cardiovascular conditions. These findings underscore the need for robust prospective studies to validate these associations and to explore underlying mechanisms.</div></div>","PeriodicalId":11975,"journal":{"name":"European journal of obstetrics, gynecology, and reproductive biology","volume":"312 ","pages":"Article 114081"},"PeriodicalIF":2.1,"publicationDate":"2025-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144177577","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intracavitary-electrohysterogram: novel technique for assessing uterine peristalsis and electrophysiology in non-pregnant women (letter)","authors":"Jose Alberola-Rubio ,&nbsp;Javier Garcia-Casado","doi":"10.1016/j.ejogrb.2025.114075","DOIUrl":"10.1016/j.ejogrb.2025.114075","url":null,"abstract":"","PeriodicalId":11975,"journal":{"name":"European journal of obstetrics, gynecology, and reproductive biology","volume":"311 ","pages":"Article 114075"},"PeriodicalIF":2.1,"publicationDate":"2025-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144123419","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}