European journal of obstetrics, gynecology, and reproductive biology最新文献

{"title":"The effect of dynamic neuromuscular stabilization training in dysfunctional voiding: A randomized clinical trial.","authors":"Talya Melikoglu, Seda Saka, Duygu Sahin Altac, Tibet Erdogru","doi":"10.1016/j.ejogrb.2025.03.031","DOIUrl":"https://doi.org/10.1016/j.ejogrb.2025.03.031","url":null,"abstract":"<p><strong>Objective: </strong>Dynamic Neuromuscular Stabilization (DNS) training may provide positive effects in adults with Dysfunctional Voiding (DV), considering the regulating effects on intra-abdominal pressure. The purpose of this study was to investigate the effect of DNS on uroflowmetry parameters, severity of symptoms and quality of life (QoL).</p><p><strong>Study design: </strong>Thirty-four adults who were diagnosed with DV were randomized into Group 1: conservative treatment (n = 17) or Group 2: conservative treatment combined with DNS training (n = 17). Both groups received treatment for six weeks. Uroflowmetry parameters, severity of symptoms with \"Dysfunctional Voiding and Incontinence Scoring System (DVISS)\" and QoL with \"The Short-Form 36 Health Survey (SF-36)\" were evaluated baseline and after intervention.</p><p><strong>Results: </strong>While improvement was achieved in some uroflowmetry parameters, DVISS score and many SF-36 subscale scores in both groups (p < 0.05), there was statistically difference in corrected maximum flow rate (cQmax) value from uroflowmetry parameters between groups at week 6 in favor of Group 2 (p = 0.04).</p><p><strong>Conclusion: </strong>In summary, the results of this randomized clinical trial considered that conservative treatment combined with DNS training could be used as clinically a different treatment approach.</p>","PeriodicalId":11975,"journal":{"name":"European journal of obstetrics, gynecology, and reproductive biology","volume":"309 ","pages":"97-106"},"PeriodicalIF":2.1,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143669253","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Update on the challenges of labor and delivery","authors":"Tullio Ghi,&nbsp;Andrea Dall’Asta","doi":"10.1016/j.ejogrb.2025.02.061","DOIUrl":"10.1016/j.ejogrb.2025.02.061","url":null,"abstract":"","PeriodicalId":11975,"journal":{"name":"European journal of obstetrics, gynecology, and reproductive biology","volume":"308 ","pages":"Page 240"},"PeriodicalIF":2.1,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143619649","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Counseling women with obstetric anal sphincter injury – Risk of recurrence and the influence of mode of second delivery on subsequent anal incontinence – A systematic review and meta-analysis","authors":"Ella-Josephine Mørch ,&nbsp;Kathrine Perslev ,&nbsp;Tine Wrønding ,&nbsp;Anna Aabakke ,&nbsp;·Hanna Jangö","doi":"10.1016/j.ejogrb.2025.03.018","DOIUrl":"10.1016/j.ejogrb.2025.03.018","url":null,"abstract":"<div><div>Obstetric anal sphincter injury (OASI) is a severe complication of vaginal delivery. Up to 50% of women with OASI will experience anal incontinence at long-term. However, it is uncertain whether an elective cesarean section (CS) in a subsequent pregnancy following OASI decreases the risk of anal incontinence. The aim of this study was to assess the risk of recurrent OASI in a subsequent pregnancy after a first delivery with OASI. Additionally, we wanted to evaluate the impact of recurrent OASI on the risk of anal incontinence, and to determine whether the CS was protective against anal incontinence in women with a first delivery with OASI.</div><div>Literature searches were made in PubMed, Cochrane, and Embase, the last search was made in May 2024. Studies were screened and study quality was assessed using “SIGN – Methodology Checklist”.</div><div>Thirteen studies (including 3 020 897 women) were included in the <em>meta</em>-analysis on risk of recurrent OASI. OASI in the first delivery increased the risk of recurrent OASI in the second delivery fivefold compared to women without previous OASI OR 4.9 (95%CI 4.0–5.9). The overall risk of acquiring a recurrent OASI was 6.1% (95%CI 5.9%-6.2%).</div><div>Five studies (including 2 330 women) were included in the <em>meta</em>-analysis assessing the effect of mode of subsequent delivery on anal incontinence. The risk of anal incontinence was non-significantly increased in women with a second vaginal delivery OR 1.1 (95%CI 0.9–1.4). Four studies (including 2 300 women) were included in the <em>meta</em>-analysis on the risk of developing anal incontinence after recurrent OASI. The risk of anal incontinence was increased in women with recurrent OASI compared to women with OASI in the first delivery and a subsequent delivery without OASI OR 1.6 (95%CI 1.3–2.0).</div><div>In conclusion, we found an increased risk of recurrent OASI in the second delivery for women with a previous OASI, compared to women without previous OASI. The risk of anal incontinence was increased in women with recurrent OASI. The risk of new onset or worsening of anal incontinence was not associated with mode of the second delivery. Women with previous OASI should be informed about the increased risk of recurrence and that elective CS is not necessarily protective against anal incontinence.</div></div>","PeriodicalId":11975,"journal":{"name":"European journal of obstetrics, gynecology, and reproductive biology","volume":"309 ","pages":"Pages 14-22"},"PeriodicalIF":2.1,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143628942","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Immediate skin-to-skin contact during cesarean section – A pilot study with simulation characters","authors":"Leena Taittonen ,&nbsp;Tanja Mäkynen ,&nbsp;Tiina-Liisa Erkinheimo","doi":"10.1016/j.ejogrb.2025.03.004","DOIUrl":"10.1016/j.ejogrb.2025.03.004","url":null,"abstract":"<div><h3>Background</h3><div>In extended gentle caesarean section mother sees the baby when the baby is born but does not get the baby directly to skin contact from the operation area. A caesarean section with a drape with a transparent window allows mother to have a direct skin contact with the newborn. This method has not been studied earlier.</div></div><div><h3>Aim</h3><div>A pilot study to describe one traditional way and two gentle ways of taking a newborn to the mother’s skin contact during a cesarean section and to analyse the time lapse between the umbilical cut and the placement of the child to skin contact.</div></div><div><h3>Methods</h3><div>The simulation (SIM) characters were the study subjects. In the first method, the mother could not see the child through an opaque section drape. The operator gave the baby to the midwife, who then took the baby to the mother. In the second method, the mother saw the baby through a transparent anesthesy cover. The baby was otherwise handled as in the first method. In the third method, a drape with a transparent window was used. Here, the mother saw the baby when the baby was born. The baby was passed through the drape opening to the mother’s skin contact. Time lapse between umbilical cut and skin contact was analysed.</div></div><div><h3>Results</h3><div>In the first and second methods, the time between the umbilical cut and the mothers’ skin contact ranged from 11 to 20 and in the third 20 to 65 s. In the third method a minor technical difficulty was seen once.</div></div><div><h3>Conclusion</h3><div>The method of giving the baby through a transparent drape with a window to the mother’s skin contact during a caesarean section is not superior as measured in time, but it might improve bonding between the mother and the baby.</div></div>","PeriodicalId":11975,"journal":{"name":"European journal of obstetrics, gynecology, and reproductive biology","volume":"309 ","pages":"Pages 23-26"},"PeriodicalIF":2.1,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143637598","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"TRANSFER: ThReatened preterm birth, assessment of the need for in-utero tranSFER between 22 + 0–23 + 6 weeks’ gestation, a multicentre prospective service evaluation across the United Kingdom","authors":"Melanie Griffin ,&nbsp;Adam Smith-Collins ,&nbsp;Victoria Hodgetts-Morton ,&nbsp;Terry Hughes ,&nbsp;Laura Magill ,&nbsp;Rita Perry ,&nbsp;Katie Morris ,&nbsp;TRANSFER project collaborative, UK","doi":"10.1016/j.ejogrb.2025.03.030","DOIUrl":"10.1016/j.ejogrb.2025.03.030","url":null,"abstract":"<div><div>TRANSFER was established following updated guidance from British Association of Perinatal Medicine, suggesting offering survival focussed care from 22 + 0 weeks’ gestation. The number of women presenting with threatened preterm birth at this gestation is unknown; essential data to facilitate adequate service provision and planning for UK perinatal services.</div></div><div><h3>Objectives</h3><div>To identify women presenting with threatened preterm birth between 22 + 0–23 + 6 weeks’ gestation across the UK and determine the number presenting ou + tside an obstetric unit with a Level 3 NICU. Record the number of in-utero transfers of women presenting between 22 + 0––23 + 6 weeks’ gestation and determine the number of women who deliver prior to 24 weeks’ gestation in units without a Level 3 NICU.</div></div><div><h3>Design</h3><div>Multicentre prospective service evaluation.</div></div><div><h3>Setting</h3><div>90 UK maternity units.</div></div><div><h3>Patients</h3><div>Women presenting with threatened preterm birth between 22 + 0–23 + 6 weeks’ gestation between 17/5/21–30/6/22.</div></div><div><h3>Main outcome measures</h3><div>Number of women presenting in each geographical region, need for in utero transfer, length of antenatal hospital stay and use of biomarkers to predict preterm birth.</div></div><div><h3>Results</h3><div>Between 22 + 0–23 + 6 weeks’ gestation:</div><div>1. 511 women presented with threatened preterm birth to UK obstetric units.</div><div>2. 286 (56%) women presented to obstetric units without level 3 NICU.</div><div>3. 217 (76%) women required transfer.</div><div>4. 41 (8%) women delivered in a unit without a Level 3 NICU (10 (24%) opted for survival focussed care).</div></div><div><h3>Conclusions</h3><div>Women presenting with threatened preterm birth between 22 + 0–23 + 6 weeks gestation is higher than anticipated and is likely to be an under-representation of actual number of presentations.</div></div>","PeriodicalId":11975,"journal":{"name":"European journal of obstetrics, gynecology, and reproductive biology","volume":"309 ","pages":"Pages 73-78"},"PeriodicalIF":2.1,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143644783","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Implementation of blood pressure telemonitoring in high-risk pregnancies; a multicenter quantitative analysis of patient experiences in the SAFE@home study","authors":"Shinta L. Moes ,&nbsp;Martine Depmann ,&nbsp;Ingelin Kvamme ,&nbsp;Victoria M.C. Veenis ,&nbsp;Elles In ’T. Anker ,&nbsp;Jacques Dirken ,&nbsp;Leonoor Van Eerden ,&nbsp;Arie Franx ,&nbsp;Sanne Gordijn ,&nbsp;Roel De Heus ,&nbsp;Steven Koenen ,&nbsp;Maarten M.H. Lahr ,&nbsp;A. Titia Lely ,&nbsp;Flip Van Der Made ,&nbsp;Lindy Santegoets ,&nbsp;Marc Spaanderman ,&nbsp;Ewoud Schuit ,&nbsp;Mireille N. Bekker","doi":"10.1016/j.ejogrb.2025.03.028","DOIUrl":"10.1016/j.ejogrb.2025.03.028","url":null,"abstract":"<div><h3>Objective</h3><div>This study evaluates patient experiences with the SAFE@home platform for telemonitoring of blood pressure (BP) and symptom tracking in patients high-risk pregnancies. We hypothesized patients would perceive telemonitoring as usable and patient-centered and aimed to identify barriers and facilitators to aid future digital health scale-up.</div></div><div><h3>Methods</h3><div>A quantitative analysis within a cohort study across 11 hospitals was conducted. Patients with a high risk of or established HDP home monitored their BP and symptoms daily via the SAFE@home platform. The SAFE@home group had less composite adverse outcomes (17.2 % vs. 21.5) compared to the usual care group. The patient satisfaction and perceived quality of care (PSPQC) questionnaire and client centered care questionnaire (CCCQ) were answered on a 5-point Likert-scale. Primary outcomes were usability and client-centeredness, with ≥ 20 % disagreement indicating barriers and ≥ 80 % agreement indicating facilitators.</div></div><div><h3>Results</h3><div>Of the 606 participants, 376 (62%) completed the survey. The majority indicated high usability for SAFE@home: 98% found it useful for BP monitoring, and 86–95% rated it easy to use. Around 68% felt more in control, 81% appreciated the alignment with personal preferences and 92% would recommend SAFE@home to others. However, 51% of the patients felt they could independently manage their care and 25% did not know who to contact with technical issues.</div></div><div><h3>Conclusion</h3><div>Telemonitoring of BP and symptoms in high-risk pregnancies demonstrates high usability and acceptance among patients, improving engagement and control. While autonomy and technical support require improvement, SAFE@home represents a feasible and scalable model for integrating digital care into obstetrics.</div></div>","PeriodicalId":11975,"journal":{"name":"European journal of obstetrics, gynecology, and reproductive biology","volume":"308 ","pages":"Pages 201-207"},"PeriodicalIF":2.1,"publicationDate":"2025-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143600782","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Alpha-fetoprotein (AFP) is reduced at 36 weeks' gestation in pregnancies destined to deliver small for gestational age infants.","authors":"Joshua Masci, Manju Kandel, Susan P Walker, Ping Cannon, Tuong-Vi Nguyen, Georgia P Wong, Teresa M MacDonald, Natalie J Hannan, Tu'uhevaha J Kaitu'u-Lino, Lucy A Bartho","doi":"10.1016/j.ejogrb.2025.03.027","DOIUrl":"https://doi.org/10.1016/j.ejogrb.2025.03.027","url":null,"abstract":"<p><p>Alpha-fetoprotein (AFP) is a protein commonly used to screen for aneuploidy in pregnancy. This study measured circulating AFP in maternal plasma at 36 weeks' gestation preceding diagnosis of term preeclampsia or delivery of a small for gestational age infant (SGA; <10 % birthweight centile) in a case-cohort design (122 SGA; 23 preeclampsia; 182 controls). AFP was significantly reduced in SGA < 5th birthweight centile (n = 51; P = 0.002) but not changed preceding preeclampsia diagnosis. This suggests that AFP is reduced near term preceding SGA diagnosis and may have potential as a biomarker if combined with other candidate molecules.</p>","PeriodicalId":11975,"journal":{"name":"European journal of obstetrics, gynecology, and reproductive biology","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143630255","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intrauterine twin pregnancy complicated by cornual heterotopic pregnancy: A case report and narrative review","authors":"Li Gao ,&nbsp;Yan-Lin Wang","doi":"10.1016/j.ejogrb.2025.03.026","DOIUrl":"10.1016/j.ejogrb.2025.03.026","url":null,"abstract":"<div><h3>Background</h3><div>Intrauterine twin pregnancy complicated by cornual heterotopic pregnancy is a rare pregnancy situation that demands effective intervention to avert rupture of the cornual pregnancy, while also striving to preserve the intrauterine fetus.</div></div><div><h3>Case description</h3><div>A 31-year-old woman presented with a complex pregnancy scenario involving an intrauterine twin gestation alongside a cornual heterotopic pregnancy subsequent to in vitro fertilization (IVF) treatment. Under the guidance of abdominal ultrasound, a transabdominal puncture was performed to administer potassium chloride directly at the site of fetal heartbeats for the purpose of fetal reduction, and to aspirate a portion of the fluid within the gestational sac to reduce its volume. Two male infants via cesarean section at 31 weeks’ gestation due to premature rupture of membranes. Postoperative follow-up revealed no abnormalities in the physical and intellectual development of the two boys.</div></div><div><h3>Conclusions</h3><div>For cases of cornual pregnancy with concomitant intrauterine pregnancy, laparoscopic surgery is a treatment option with a relatively high success rate. However, selective fetal reduction may be more advantageous in reducing the miscarriage rate of the intrauterine pregnancy. Compared to transvaginal puncture for fetal reduction, transabdominal ultrasound-guided puncture potassium chloride injection for fetal reduction has a lower infection rate. Additionally, aspirating the fluid from the gestational sac during fetal reduction may help to reduce the size of the gestational sac, thereby lowering the risk of uterine rupture at the cornual region.</div></div>","PeriodicalId":11975,"journal":{"name":"European journal of obstetrics, gynecology, and reproductive biology","volume":"308 ","pages":"Pages 190-194"},"PeriodicalIF":2.1,"publicationDate":"2025-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143592504","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Another link in the chain- Diet, digestive health, and pelvic floor integrity: A cross-cultural study","authors":"Reut Rotem ,&nbsp;Michal Ovadia ,&nbsp;Barry A. O’Reilly ,&nbsp;Orfhlaith E. O’Sullivan ,&nbsp;Yael Yagur ,&nbsp;Ron Schonman ,&nbsp;Nissim Arbib ,&nbsp;Zvi Klein ,&nbsp;Yair Daykan","doi":"10.1016/j.ejogrb.2025.03.019","DOIUrl":"10.1016/j.ejogrb.2025.03.019","url":null,"abstract":"<div><h3>Objective</h3><div>To explore the association between impaired bowel function (IBF), diet and their collective impact on the incidence of different pelvic organ prolapse (POP) compartments.</div></div><div><h3>Study design</h3><div>This cross-sectional, international, multi-center study was conducted among patients undergoing pelvic floor repair in Ireland and Israel. Adherence to the Mediterranean diet and the presence of IBF were assessed using validated questionnaires (The Mediterranean Diet Adherence Questionnaire and the Patient Assessment of Constipation Symptoms, respectively). General demographic information, clinical details, and intraoperative data were extracted from the electronic medical records in each hospital. A univariate analysis was followed by a multivariate one, and correlations were assessed using Spearman’s rho coefficient.</div></div><div><h3>Results</h3><div>Among the 204 patients enrolled, 105 (51.5 %) were categorized into the IBF group, and 99 (48.5 %) into the NBF group. There was no difference in age, parity, body mass index and obesity rate between groups. Patients in the IBF group were more often nullipara (1 % Vs. 8.1 %, p = 0.01) and exhibited significantly lower rates of adherence to the Mediterranean diet than the NBF group (22.0 % vs. 70.5 %, p = 0.01). Cystocele, cul-de-sac (enterocele), and genital hiatus prolapse were more prevalent in the IBF group. The distribution of surgical repair procedures was similar between the two groups. Multivariate logistic regression analysis revealed a significant association between surgical repair involving the anterior wall and low adherence to the Mediterranean diet.</div></div><div><h3>Conclusion</h3><div>This study suggests that IBF and constipation shows specific patterns of vaginal wall prolapse as cystocele and enterocele, underscoring the importance of dietary habits in the prevention and management of pelvic floor disorders.</div></div>","PeriodicalId":11975,"journal":{"name":"European journal of obstetrics, gynecology, and reproductive biology","volume":"308 ","pages":"Pages 222-227"},"PeriodicalIF":2.1,"publicationDate":"2025-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143609184","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of single-site and three-port hysterectomy for benign uterine diseases: A randomised trial (LESS-H)","authors":"Ok-Ju Kang,&nbsp;Joo-Hyun Nam,&nbsp;Jeong-Yeol Park","doi":"10.1016/j.ejogrb.2025.03.005","DOIUrl":"10.1016/j.ejogrb.2025.03.005","url":null,"abstract":"<div><h3>Objective</h3><div>To evaluate the feasibility and safety of laparoendoscopic single-site (LESS) vaginal hysterectomy compared to conventional three-port laparoscopic-assisted vaginal hysterectomy (LAVH) for benign and pre-invasive uterine disease.</div></div><div><h3>Methods</h3><div>We conducted a prospective randomized controlled trial that included patients who were scheduled to undergo hysterectomy using laparoscopic surgery for the benign and pre-invasive uterine diseases. The primary endpoint was to compare the ratio of patients discharged within 2 days after surgery between LESS LAVH and three-port LAVH groups.</div></div><div><h3>Results</h3><div>A total of 428 patients were randomised to the LESS group (n = 216) and the conventional group (n = 212). The two groups did not show significant differences in the proportion of patients discharged within two days after surgery (LESS vs. three-port, 93 % vs. 90 %, <em>P</em> = 0.277). There were also no significant differences in operating time, hemoglobin change, average length of postoperative hospital stay and perioperative complications. While the visual analogue score (VAS) pain score during hospital stay was similar between the two groups, the pain score at the first outpatient visit (2 weeks after surgery) was significantly lower in the LESS group (LESS vs. three-port, 3.29 vs. 3.93, <em>P</em> = 0.012).</div></div><div><h3>Conclusions</h3><div>Although LESS LAVH was not superior to conventional multiport surgery, it is a feasible, safe procedure for managing benign and pre-invasive uterine diseases.</div></div><div><h3>Trial registration</h3><div><span><span>Clinicaltrial.gov</span><svg><path></path></svg></span> identifier number: NCT01679548, <span><span>https://clinicaltrials.gov/study/NCT01679548</span><svg><path></path></svg></span>.</div></div>","PeriodicalId":11975,"journal":{"name":"European journal of obstetrics, gynecology, and reproductive biology","volume":"308 ","pages":"Pages 251-256"},"PeriodicalIF":2.1,"publicationDate":"2025-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143619646","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}