European Journal of Dermatology最新文献_第6页

Late-onset encephalitis as an immune-related adverse event of avelumab therapy in a patient with Merkel cell carcinoma of unknown primary. 原发性不明的默克尔细胞癌患者迟发性脑炎作为avelumab治疗的免疫相关不良事件

IF 1.9 4区医学

European Journal of Dermatology Pub Date : 2026-08-01 DOI: 10.1684/ejd.2026.5086

Karen Nomura, Yasuaki Ogura, Reiko Kageyama, Kazuki Watanabe, Tomohiko Nakamura, Tetsuya Honda

引用次数: 0

Improving dermatology tele-expertise through physician training: evidence from a large real-world cohort. 通过医生培训提高皮肤科远程专业知识：来自现实世界大型队列的证据。

IF 1.9 4区医学

European Journal of Dermatology Pub Date : 2026-08-01 DOI: 10.1684/ejd.2026.5111

Cyrus Corrente, Adrien Baudry, Sabine Pedailles

{"title":"Improving dermatology tele-expertise through physician training: evidence from a large real-world cohort.","authors":"Cyrus Corrente, Adrien Baudry, Sabine Pedailles","doi":"10.1684/ejd.2026.5111","DOIUrl":"https://doi.org/10.1684/ejd.2026.5111","url":null,"abstract":"Tele-expertise (TE) has emerged as a key strategy to address limited access to dermatological care. However, its performance may depend on the quality of requests submitted by primary care physicians. To evaluate dermatological TE activity in a regional network and to assess the impact of continuing education in dermatology and dermoscopy on the quality and efficiency of TE requests. We conducted a retrospective single-centre study of all TE requests received between January 1, 2022 and December 31, 2024 at the Centre Hospitalier Intercommunal d'Alençon-Mamers using the Omnidoc platform. After standardization, 3,266 TE cases were analysed. Data from TE requests were cross-referenced with patient records when in-person consultation occurred. Request quality and TE performance were compared between trained and untrained general practitioners. General practitioners accounted for 99.2% of TE requests, mainly for diagnostic purposes (92.4%). The most frequent indications were skin cancer screening (59.6%), inflammatory dermatoses (9.7%), and infections (9.5%). TE provided rapid specialist input (median response time: 13 hours), with only 4% of requests rejected due to insufficient information. TE avoided face-to-face consultations in 51% of cases, with high diagnostic concordance (92.4%). Training significantly improved request quality. This resulted in more efficient specialist responses. TE is an effective tool to optimize dermatological care pathways but is highly dependent on the requesting physician's level of training. Integrating structured education in dermatology and dermoscopy transforms TE into a high-performance, learning healthcare model. Investment in training is therefore essential to maximize the clinical impact of TE.","PeriodicalId":11968,"journal":{"name":"European Journal of Dermatology","volume":"36 4","pages":"339-344"},"PeriodicalIF":1.9,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148900158","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Baseline C-reactive protein independently predicts treatment response and survival in metastatic melanoma patients receiving first-line immune checkpoint inhibitors. 基线c反应蛋白独立预测接受一线免疫检查点抑制剂的转移性黑色素瘤患者的治疗反应和生存期。

IF 1.9 4区医学

European Journal of Dermatology Pub Date : 2026-08-01 DOI: 10.1684/ejd.2026.5117

Thilo Gambichler, Clara Ruhe, Sera S Weyer-Fahlbusch, Laura Susok, Nessr Abu Rached

引用次数: 0

Amoxicillin delabelling in suspected clavulanate-selective delayed hypersensitivity: a case report using lymphocyte transformation and drug provocation tests. 疑似克拉维酸选择性延迟性超敏反应的阿莫西林去标签：使用淋巴细胞转化和药物激发试验的病例报告。

IF 1.9 4区医学

European Journal of Dermatology Pub Date : 2026-08-01 DOI: 10.1684/ejd.2026.5116

Souta Kobayashi, Yasuaki Ikuno, Haruna Shintani, Masahiro Yamada, Yasuhiro Maeda, Akihiko Yamaguchi, Toshifumi Takahashi, Akiko Arakawa, Noriki Fujimoto

引用次数: 0

Epidemiology update and refractoriness to initial pharmacotherapy of chronic spontaneous urticaria: insight from an Italian primary care cohort. 慢性自发性荨麻疹初始药物治疗的流行病学更新和难治性：来自意大利初级保健队列的见解。

IF 1.9 4区医学

European Journal of Dermatology Pub Date : 2026-08-01 DOI: 10.1684/ejd.2026.5106

Francesco Lapi, Ettore Marconi, Alessandro Rossi, Iacopo Cricelli, Ornella Bonavita, Lucia Casoli, Diletta Valsecchi, Barbara Giomi, Claudio Cricelli

{"title":"Epidemiology update and refractoriness to initial pharmacotherapy of chronic spontaneous urticaria: insight from an Italian primary care cohort.","authors":"Francesco Lapi, Ettore Marconi, Alessandro Rossi, Iacopo Cricelli, Ornella Bonavita, Lucia Casoli, Diletta Valsecchi, Barbara Giomi, Claudio Cricelli","doi":"10.1684/ejd.2026.5106","DOIUrl":"https://doi.org/10.1684/ejd.2026.5106","url":null,"abstract":"Chronic spontaneous urticaria (CSU) is characterized by hives and/or angioedema for at least six weeks, impacting quality of life and healthcare costs. Objectives: This study aimed to update CSU epidemiology and assess refractoriness to initial pharmacotherapy and related determinants in Italian primary care. A cohort of patients aged 15 years and older with newly diagnosed CSU was identified from Italian primary care data from January 1, 2002, to September 30, 2022. Prevalence and incidence were calculated as % and rate per 1000 person-years, respectively. The study investigated occurrence and determinants of refractoriness to initial pharmacotherapy (H1-antihistamines and/or steroids) using multivariable Cox regression analysis. Annual CSU prevalence ranged from 0.41% in 2002 to 0.35% in 2022. The incidence was 2.07-1.93 per 1000 person-years. A cohort of 7,018 patients with CSU was identified during the study period. Of these, 50% experienced refractoriness to initial pharmacotherapy, with most events occurring within two months. Factors associated with increased refractoriness risk included age 55 years and older, autoimmune thyroiditis, asthma/COPD, unspecified allergies, and immunosuppressive drug use, including steroids. Patients who developed refractoriness were 52% more likely to be referred to dermatologists or allergists compared to non-refractory patients. These findings show that many patients, particularly those with certain coexisting conditions, do not respond well to initial CSU pharmacotherapy. By identifying these patients early through a decision support system, GPs could promptly refer them to specialists for second-line therapy evaluation.","PeriodicalId":11968,"journal":{"name":"European Journal of Dermatology","volume":"36 4","pages":"353-361"},"PeriodicalIF":1.9,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148900138","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Review of the European Society for Photodynamic Therapy (Euro-PDT) Annual Congress 2025. 欧洲光动力治疗学会（Euro-PDT） 2025年年会综述。

IF 1.9 4区医学

European Journal of Dermatology Pub Date : 2026-08-01 DOI: 10.1684/ejd.2026.5127

Colin A Morton, Rolf-Markus Szeimies, Lasse R Braathen

引用次数: 0

Misdiagnosis of an odontogenic cutaneous fistula as a first branchial cleft cyst and diagnostic insights: a paediatric case report. 牙源性皮瘘误诊为第一鳃裂囊肿和诊断见解：一个儿科病例报告。

IF 1.9 4区医学

European Journal of Dermatology Pub Date : 2026-08-01 DOI: 10.1684/ejd.2026.5104

Hongwei Fang, Jiahui Jin, Feifan Qi, Liang Li, Lixin Chen, Guangping Liu

引用次数: 0

Dupilumab treatment of linear IgA bullous dermatosis in a child. 杜匹单抗治疗儿童线性IgA大疱性皮肤病。

IF 1.9 4区医学

European Journal of Dermatology Pub Date : 2026-08-01 DOI: 10.1684/ejd.2026.5129

Mattia Giovannini, Valentina Ruffo Di Calabria, Francesca Mori, Teresa Oranges, Greta Tronconi, Silvia Ricci, Beatrice Serra, Gabriele Simonetti, Sara Soldovieri, Cesare Filippeschi

引用次数: 0

Successful treatment of severe refractory folliculitis decalvans and lichen planopilaris phenotypic spectrum with baricitinib. 巴西替尼成功治疗重度难治性脱斑疹性毛囊炎和扁平苔藓表型谱。

IF 1.9 4区医学

European Journal of Dermatology Pub Date : 2026-08-01 DOI: 10.1684/ejd.2026.5092

Sasha Visinoni, Maria Efenesia Baffa, Carlo Pipitò, Vincenzina Rubino, Stefano Colabrese, Chiara Quitadamo, Roberto Maglie, Emiliano Antiga

引用次数: 0

Ratio of varicella-zoster virus-specific immunoglobulin G antibody titre in the late acute phase to that in the early acute phase as a novel indicator of postherpetic neuralgia in patients with herpes zoster: a single-centre retrospective cohort study. 急性期晚期水痘-带状疱疹病毒特异性免疫球蛋白G抗体滴度与急性期早期抗体滴度之比作为带状疱疹患者带状疱疹后神经痛的新指标：一项单中心回顾性队列研究

IF 1.9 4区医学

European Journal of Dermatology Pub Date : 2026-08-01 DOI: 10.1684/ejd.2026.5055

Masahiro Oka, Sae Murakami

{"title":"Ratio of varicella-zoster virus-specific immunoglobulin G antibody titre in the late acute phase to that in the early acute phase as a novel indicator of postherpetic neuralgia in patients with herpes zoster: a single-centre retrospective cohort study.","authors":"Masahiro Oka, Sae Murakami","doi":"10.1684/ejd.2026.5055","DOIUrl":"https://doi.org/10.1684/ejd.2026.5055","url":null,"abstract":"Postherpetic neuralgia (PHN) is a common but feared complication of herpes zoster (HZ) caused by latent varicella-zoster virus (VZV) reactivation. Objectives: To investigate the relationship between the late-to-early acute phase VZV immunoglobulin (Ig)G antibody (Ab) titre ratio (VZV IgG L/E ratio) and pain intensity after 90 days from onset in patients with HZ. In this hospital-based retrospective cohort study, we analysed the data of patients who met the following criteria between July 2019 and September 2024: 1) those clinically diagnosed with HZ within seven days from onset; 2) those in whom VZV IgG Ab titres were measured twice in the early and late acute phases; and 3) those in whom pain intensity was assessed at the earliest time point after 90 days from onset, using the numerical rating scale (NRS). VZV IgG Ab titres were measured by enzyme-linked immunosorbent assay. A total of 21 patients were included in the analysis. The VZV IgG L/E ratio negatively correlated with NRS score after 90 days from onset (ρ= -0.53). When PHN was defined as pain associated with HZ (rated as 3 or more on the NRS), persisting or appearing for more than 90 days after the onset of HZ, the receiver operating characteristic curve analysis revealed a cut-off value of the VZV IgG L/E ratio for PHN to be 1.8, with 100% sensitivity and 93% specificity. Our results suggest that the VZV IgG L/E ratio could serve as a novel PHN indicator.","PeriodicalId":11968,"journal":{"name":"European Journal of Dermatology","volume":"36 4","pages":"345-352"},"PeriodicalIF":1.9,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148900147","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0