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European Journal of Dermatology最新文献

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Altered expression of S100 fused-type proteins in human skin due to ultraviolet B irradiation. 紫外线B照射对人体皮肤中S100融合型蛋白表达的影响。
IF 1.9 4区 医学
European Journal of Dermatology Pub Date : 2026-06-01 DOI: 10.1684/ejd.2026.5080
Teruhiko Makino
{"title":"Altered expression of S100 fused-type proteins in human skin due to ultraviolet B irradiation.","authors":"Teruhiko Makino","doi":"10.1684/ejd.2026.5080","DOIUrl":"https://doi.org/10.1684/ejd.2026.5080","url":null,"abstract":"<p><p>Ultraviolet B (UVB) radiation profoundly affects epidermal homeostasis by inducing DNA damage, reactive oxygen species generation, and stress signalling. This review summarizes recent findings on the dynamic regulation of S100 fused-type proteins, including filaggrin (FLG), filaggrin 2 (FLG2), cornulin (CRNN), repetin (RPTN), hornerin (HRNR), trichohyalin (TCHH), and trichohyalin like protein 1 (TCHHL1) in human skin after UVB irradiation. In experiments using human skin xenografts, UVB (500 mJ/cm²) irradiation transiently upregulates proliferation-related proteins (TCHHL1, RPTN, and HRNR) and barrier-related proteins (CRNN, FLG2, and FLG) within two days, with normalization by day 7. These temporal changes correlate with activation of the ERK/p38 MAPK and STAT3 pathways, suggesting the existence of a coordinated regulatory network linking proliferation and differentiation during barrier repair. Altered expression in S100 fused-type proteins may serve as biomarkers of acute UVB responses and as targets for promoting epidermal recovery after photodamage.</p>","PeriodicalId":11968,"journal":{"name":"European Journal of Dermatology","volume":"36 3","pages":"223-228"},"PeriodicalIF":1.9,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148590973","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Coexisting pemphigus and mucous membrane pemphigoid: a case with autoantibodies against desmoglein 1 and plakin proteins. 并发天疱疮和粘膜类天疱疮：1例抗粘连蛋白1和血小板蛋白自身抗体。
IF 1.9 4区 医学
European Journal of Dermatology Pub Date : 2026-06-01 DOI: 10.1684/ejd.2026.5093
Masakazu Kakurai, Norito Ishii, Hiroshi Koga, Yoshihiro Moriyama
{"title":"Coexisting pemphigus and mucous membrane pemphigoid: a case with autoantibodies against desmoglein 1 and plakin proteins.","authors":"Masakazu Kakurai, Norito Ishii, Hiroshi Koga, Yoshihiro Moriyama","doi":"10.1684/ejd.2026.5093","DOIUrl":"https://doi.org/10.1684/ejd.2026.5093","url":null,"abstract":"","PeriodicalId":11968,"journal":{"name":"European Journal of Dermatology","volume":"36 3","pages":"285-287"},"PeriodicalIF":1.9,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148591056","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
sQUIZ your knowledge! Sudden eruption of haemorrhagic crusts in a young patient. 测试你的知识！年轻病人突然出现出血性结痂。
IF 1.9 4区 医学
European Journal of Dermatology Pub Date : 2026-06-01 DOI: 10.1684/ejd.2026.5103
Luis Ángel Zamarro-Díaz, Belén Rodríguez-Sánchez, Marina De La Puente-Alonso, Simon Goller, César Silva Ferreira, Luis Jiménez Briones, Jorge Martín-Nieto González
{"title":"sQUIZ your knowledge! Sudden eruption of haemorrhagic crusts in a young patient.","authors":"Luis Ángel Zamarro-Díaz, Belén Rodríguez-Sánchez, Marina De La Puente-Alonso, Simon Goller, César Silva Ferreira, Luis Jiménez Briones, Jorge Martín-Nieto González","doi":"10.1684/ejd.2026.5103","DOIUrl":"https://doi.org/10.1684/ejd.2026.5103","url":null,"abstract":"","PeriodicalId":11968,"journal":{"name":"European Journal of Dermatology","volume":"36 3","pages":"301-303"},"PeriodicalIF":1.9,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148591127","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Reflectance confocal microscopy examination of subungual exostosis in a child. 反射共聚焦显微镜检查儿童尺下外生症。
IF 1.9 4区 医学
European Journal of Dermatology Pub Date : 2026-06-01 DOI: 10.1684/ejd.2026.5075
Bei Qin, Lixin Chen, Ying Wang, ChengKai Li, Qinfeng Li
{"title":"Reflectance confocal microscopy examination of subungual exostosis in a child.","authors":"Bei Qin, Lixin Chen, Ying Wang, ChengKai Li, Qinfeng Li","doi":"10.1684/ejd.2026.5075","DOIUrl":"https://doi.org/10.1684/ejd.2026.5075","url":null,"abstract":"","PeriodicalId":11968,"journal":{"name":"European Journal of Dermatology","volume":"36 3","pages":"268-269"},"PeriodicalIF":1.9,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148591216","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Baricitinib for treatment of ustekinumab-induced paradoxical eczematous reactions in a patient with plaque psoriasis. Baricitinib治疗斑块型银屑病患者ustekinumab诱导的反常湿疹反应。
IF 1.9 4区 医学
European Journal of Dermatology Pub Date : 2026-06-01 DOI: 10.1684/ejd.2026.5077
Chinatsu Shobatake, Fumi Miyagawa, Yasuhiro Mitsui, Yukiko Nakanishi, Kohei Ogawa, Hideo Asada
{"title":"Baricitinib for treatment of ustekinumab-induced paradoxical eczematous reactions in a patient with plaque psoriasis.","authors":"Chinatsu Shobatake, Fumi Miyagawa, Yasuhiro Mitsui, Yukiko Nakanishi, Kohei Ogawa, Hideo Asada","doi":"10.1684/ejd.2026.5077","DOIUrl":"https://doi.org/10.1684/ejd.2026.5077","url":null,"abstract":"","PeriodicalId":11968,"journal":{"name":"European Journal of Dermatology","volume":"36 3","pages":"266-267"},"PeriodicalIF":1.9,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148591030","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Efficacy, safety, and clinical use of second-generation antihistamines for chronic spontaneous urticaria: a comprehensive review. 第二代抗组胺药治疗慢性自发性荨麻疹的疗效、安全性和临床应用综述
IF 1.9 4区 医学
European Journal of Dermatology Pub Date : 2026-06-01 DOI: 10.1684/ejd.2026.5085
Fabià Torres-Betato, Ana María Giménez Arnau, Jorge Spertino
{"title":"Efficacy, safety, and clinical use of second-generation antihistamines for chronic spontaneous urticaria: a comprehensive review.","authors":"Fabià Torres-Betato, Ana María Giménez Arnau, Jorge Spertino","doi":"10.1684/ejd.2026.5085","DOIUrl":"https://doi.org/10.1684/ejd.2026.5085","url":null,"abstract":"<p><p>Second-generation antihistamines are the mainstay of therapy for chronic spontaneous urticaria. This review summarizes current evidence on their efficacy, safety, and clinical use, including dose escalation and management in specific populations. Recent studies confirm that up-dosing up to four times the standard dose can enhance symptom control without compromising tolerability. Furthermore, these agents demonstrate an excellent cardiovascular safety profile and are generally safe for use in paediatric, elderly, and renally or hepatically impaired patients, with appropriate caution during pregnancy and lactation.</p>","PeriodicalId":11968,"journal":{"name":"European Journal of Dermatology","volume":"36 3","pages":"229-234"},"PeriodicalIF":1.9,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148591061","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prospective real-world evaluation of a new scanning handpiece for fractional carbon dioxide laser in the treatment of hypertrophic burn scars. 一种新型二氧化碳激光扫描机头治疗增生性烧伤疤痕的前瞻性评价。
IF 1.9 4区 医学
European Journal of Dermatology Pub Date : 2026-06-01 DOI: 10.1684/ejd.2026.5088
Suhaila Abouhadid, Polly Stevenson, Louise Nevitte, Kay Thomas, Beth Wright, Charankumal Thandi, Rachel Smith, Alison Clowes, Eva Blakemore, Hagar Elgezeri, Humaira Ahmed, Lesley Wiley, Nalin Nagrath, Victoria Vilenchik, Alexandra Phillips, Kyriaki Mitsaki, Amy Martinkosky, Christopher Wearn, Jonathon Pleat, Daniel Keith
{"title":"Prospective real-world evaluation of a new scanning handpiece for fractional carbon dioxide laser in the treatment of hypertrophic burn scars.","authors":"Suhaila Abouhadid, Polly Stevenson, Louise Nevitte, Kay Thomas, Beth Wright, Charankumal Thandi, Rachel Smith, Alison Clowes, Eva Blakemore, Hagar Elgezeri, Humaira Ahmed, Lesley Wiley, Nalin Nagrath, Victoria Vilenchik, Alexandra Phillips, Kyriaki Mitsaki, Amy Martinkosky, Christopher Wearn, Jonathon Pleat, Daniel Keith","doi":"10.1684/ejd.2026.5088","DOIUrl":"https://doi.org/10.1684/ejd.2026.5088","url":null,"abstract":"","PeriodicalId":11968,"journal":{"name":"European Journal of Dermatology","volume":"36 3","pages":"280-281"},"PeriodicalIF":1.9,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148591078","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pyoderma gangrenosum mimicking blue toe syndrome following endovascular treatment. 血管内治疗后的坏疽性脓皮病模拟蓝趾综合征。
IF 1.9 4区 医学
European Journal of Dermatology Pub Date : 2026-06-01 DOI: 10.1684/ejd.2026.5096
Izumi Tanaka, Mizuki Yamamoto Murata, Tsukasa Ugajin
{"title":"Pyoderma gangrenosum mimicking blue toe syndrome following endovascular treatment.","authors":"Izumi Tanaka, Mizuki Yamamoto Murata, Tsukasa Ugajin","doi":"10.1684/ejd.2026.5096","DOIUrl":"https://doi.org/10.1684/ejd.2026.5096","url":null,"abstract":"","PeriodicalId":11968,"journal":{"name":"European Journal of Dermatology","volume":"36 3","pages":"289-291"},"PeriodicalIF":1.9,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148591117","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Analysis of failure of long-term treatment with anti-IL-17A biologics for psoriasis: a cross-sectional study. 抗il - 17a生物制剂治疗银屑病的长期治疗失败分析：一项横断面研究。
IF 1.5 4区 医学
European Journal of Dermatology Pub Date : 2026-04-01 DOI: 10.1684/ejd.2026.5051
Xinyi Dai, Chenxingyue Zhang, Jiliang Lu, Suwen Du, Jiping Xia, Zhiqiang Yin
{"title":"Analysis of failure of long-term treatment with anti-IL-17A biologics for psoriasis: a cross-sectional study.","authors":"Xinyi Dai, Chenxingyue Zhang, Jiliang Lu, Suwen Du, Jiping Xia, Zhiqiang Yin","doi":"10.1684/ejd.2026.5051","DOIUrl":"https://doi.org/10.1684/ejd.2026.5051","url":null,"abstract":"","PeriodicalId":11968,"journal":{"name":"European Journal of Dermatology","volume":"36 2","pages":"188-190"},"PeriodicalIF":1.5,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148013776","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ichthyosiform pityriasis rubra pilaris-like eruption induced by ponatinib, successfully treated with topical vitamin D3 ointment. 波纳替尼引起的红斑性鱼鳞状糠疹样疹，局部用维生素D3软膏治疗成功。
IF 1.5 4区 医学
European Journal of Dermatology Pub Date : 2026-04-01 DOI: 10.1684/ejd.2026.5046
Sadanori Furudate, Yoshihide Asano
{"title":"Ichthyosiform pityriasis rubra pilaris-like eruption induced by ponatinib, successfully treated with topical vitamin D3 ointment.","authors":"Sadanori Furudate, Yoshihide Asano","doi":"10.1684/ejd.2026.5046","DOIUrl":"https://doi.org/10.1684/ejd.2026.5046","url":null,"abstract":"","PeriodicalId":11968,"journal":{"name":"European Journal of Dermatology","volume":"36 2","pages":"183-185"},"PeriodicalIF":1.5,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148014031","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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