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European Journal of Dermatology最新文献

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Coexistence of early localized and late disseminated cutaneous borreliosis in the same patient. 同一患者同时患有早期局部性和晚期播散性皮肤包虫病。
IF 2 4区 医学
European Journal of Dermatology Pub Date : 2024-10-01 DOI: 10.1684/ejd.2024.4765
Rémy Hamdan, Anne-Laure Baldassini, Anh-Thu Phan Thi, Cédric Lenormand, Véronique Jacomo, Olivier Harou, Gilles Mauduit, Annabelle Paleau, Catherine Falchero
{"title":"Coexistence of early localized and late disseminated cutaneous borreliosis in the same patient.","authors":"Rémy Hamdan, Anne-Laure Baldassini, Anh-Thu Phan Thi, Cédric Lenormand, Véronique Jacomo, Olivier Harou, Gilles Mauduit, Annabelle Paleau, Catherine Falchero","doi":"10.1684/ejd.2024.4765","DOIUrl":"https://doi.org/10.1684/ejd.2024.4765","url":null,"abstract":"","PeriodicalId":11968,"journal":{"name":"European Journal of Dermatology","volume":"34 5","pages":"550-551"},"PeriodicalIF":2.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142715821","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
sQUIZ your knowledge! Not your usual hand foot syndrome: peculiar taxane toxicity worth remembering. 唤醒您的知识！非同寻常的手足综合症：值得记住的特殊类固醇毒性。
IF 2 4区 医学
European Journal of Dermatology Pub Date : 2024-10-01 DOI: 10.1684/ejd.2024.4781
Joana Xara, Duarte Flor, Mónica Mariano, Inês Coutinho
{"title":"sQUIZ your knowledge! Not your usual hand foot syndrome: peculiar taxane toxicity worth remembering.","authors":"Joana Xara, Duarte Flor, Mónica Mariano, Inês Coutinho","doi":"10.1684/ejd.2024.4781","DOIUrl":"https://doi.org/10.1684/ejd.2024.4781","url":null,"abstract":"","PeriodicalId":11968,"journal":{"name":"European Journal of Dermatology","volume":"34 5","pages":"580-581"},"PeriodicalIF":2.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142716032","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
sQUIZ your knowledge! A painful plaque on the heel of a young female. 测验您的知识！年轻女性脚后跟上的疼痛斑块。
IF 2 4区 医学
European Journal of Dermatology Pub Date : 2024-10-01 DOI: 10.1684/ejd.2024.4776
Yoshitsugu Sunaga, Takayuki Suyama
{"title":"sQUIZ your knowledge! A painful plaque on the heel of a young female.","authors":"Yoshitsugu Sunaga, Takayuki Suyama","doi":"10.1684/ejd.2024.4776","DOIUrl":"https://doi.org/10.1684/ejd.2024.4776","url":null,"abstract":"","PeriodicalId":11968,"journal":{"name":"European Journal of Dermatology","volume":"34 5","pages":"571-572"},"PeriodicalIF":2.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142716028","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Reflectance confocal microscopy for the diagnosis of facial cutaneous lupus erythematosus and tinea incognito in children: a retrospective study. 反射共聚焦显微镜用于诊断儿童面部皮肤红斑狼疮和癣菌：一项回顾性研究。
IF 2 4区 医学
European Journal of Dermatology Pub Date : 2024-10-01 DOI: 10.1684/ejd.2024.4766
Lixin Chen, Ying Wang, Min Ren, Xiaofang Ping, Qinfeng Li
{"title":"Reflectance confocal microscopy for the diagnosis of facial cutaneous lupus erythematosus and tinea incognito in children: a retrospective study.","authors":"Lixin Chen, Ying Wang, Min Ren, Xiaofang Ping, Qinfeng Li","doi":"10.1684/ejd.2024.4766","DOIUrl":"https://doi.org/10.1684/ejd.2024.4766","url":null,"abstract":"","PeriodicalId":11968,"journal":{"name":"European Journal of Dermatology","volume":"34 5","pages":"564-566"},"PeriodicalIF":2.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142716026","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
VAV1 regulates cell growth in cutaneous T-cell lymphoma via the BAMBI/BMF signalling pathway. VAV1 通过 BAMBI/BMF 信号通路调节皮肤 T 细胞淋巴瘤的细胞生长。
IF 2 4区 医学
European Journal of Dermatology Pub Date : 2024-10-01 DOI: 10.1684/ejd.2024.4752
Yimeng Wang, Tingting Li, Guanyu Wang, Chunlei Zhang
{"title":"VAV1 regulates cell growth in cutaneous T-cell lymphoma via the BAMBI/BMF signalling pathway.","authors":"Yimeng Wang, Tingting Li, Guanyu Wang, Chunlei Zhang","doi":"10.1684/ejd.2024.4752","DOIUrl":"https://doi.org/10.1684/ejd.2024.4752","url":null,"abstract":"<p><p>Cutaneous T-cell lymphomas (CTCLs) are a heterogeneous group of tumours originating from the cutaneous infiltration of clonal malignant T cells. VAV1 is a hematopoietic signal transducer and an oncogene in various cancers, however, the relevance of aberrant VAV1 expression in CTCL pathogenesis remains unclear. This study aimed to evaluate the expression pattern and underlying pathogenic mechanisms of VAV1 in CTCLs. The expression of VAV1 in CTCL tumour tissues and benign inflammatory dermatoses skin samples were examined by immunohistochemistry. CTCL cells were also transfected with lentiviral-based VAV1 gene knockdown vectors, and the effects of VAV1 knockdown on cell proliferation and apoptosis in CTCL cells was determined by MTS assay and flow cytometry. Transcriptomic sequencing was performed to detect the direct downstream targets of VAV1 silencing. RT-qPCR and western blot analysis were used to verify the transcriptomic analysis results. High expression of VAV1 was observed in CTCL tissues (n = 25) compared with benign inflammatory dermatoses (n = 23) using immunohistochemistry. VAV1 knockdown in two CTCL cell lines decreased cell proliferation and increased the percentage of apoptotic cells. Moreover, messenger RNA and protein expression of Bcl-2-modifying factor was increased, whereas that of bone morphogenetic proteins and activin membrane-bound inhibitor was downregulated in VAV1-silenced CTCL cells. VAV1 silencing induces apoptosis and inhibits cell growth, which is associated with upregulation of Bcl-2 modifying factor and downregulation of bone morphogenetic proteins and activin membrane-bound inhibitor. Therefore, VAV1 may be a potential tumour marker and therapeutic target for CTCLs.</p>","PeriodicalId":11968,"journal":{"name":"European Journal of Dermatology","volume":"34 5","pages":"480-489"},"PeriodicalIF":2.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142716038","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clues on dermoscopy: Arborizing and dotted vessels: an atypical vascular pattern associated with atrophic dermatofibroma. 皮肤镜的线索：树枝状和点状血管：与萎缩性皮纤维瘤相关的非典型血管形态。
IF 2 4区 医学
European Journal of Dermatology Pub Date : 2024-10-01 DOI: 10.1684/ejd.2024.4775
María Córdoba García-Rayo, Elisa Hernández De La Torre Ruiz, Paloma García Piqueras
{"title":"Clues on dermoscopy: Arborizing and dotted vessels: an atypical vascular pattern associated with atrophic dermatofibroma.","authors":"María Córdoba García-Rayo, Elisa Hernández De La Torre Ruiz, Paloma García Piqueras","doi":"10.1684/ejd.2024.4775","DOIUrl":"https://doi.org/10.1684/ejd.2024.4775","url":null,"abstract":"","PeriodicalId":11968,"journal":{"name":"European Journal of Dermatology","volume":"34 5","pages":"569-570"},"PeriodicalIF":2.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142715814","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
sQuiz your knowledge! An erythematous nodule on the leg: the importance of dermoscopy for diagnosis. 知识问答腿部红斑结节：皮肤镜检查对诊断的重要性。
IF 2 4区 医学
European Journal of Dermatology Pub Date : 2024-10-01 DOI: 10.1684/ejd.2024.4777
Turki Kmar, Fatma Hammami, Hamida Turki
{"title":"sQuiz your knowledge! An erythematous nodule on the leg: the importance of dermoscopy for diagnosis.","authors":"Turki Kmar, Fatma Hammami, Hamida Turki","doi":"10.1684/ejd.2024.4777","DOIUrl":"https://doi.org/10.1684/ejd.2024.4777","url":null,"abstract":"","PeriodicalId":11968,"journal":{"name":"European Journal of Dermatology","volume":"34 5","pages":"572-574"},"PeriodicalIF":2.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142716029","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Parallel pigmented network in lentigo maligna: a case series and correlation with in vivo reflectance confocal microscopy. 恶性白斑中的平行色素网：病例系列及与活体反射共聚焦显微镜的相关性。
IF 2 4区 医学
European Journal of Dermatology Pub Date : 2024-10-01 DOI: 10.1684/ejd.2024.4747
Giulia Greta Dradi, Reyes Gamo Villegas, María Uxmal Floristán Murzubal, Fernando Pinedo Moraleda, Claudia Sarró Fuente, José Luis López Estebaranz
{"title":"Parallel pigmented network in lentigo maligna: a case series and correlation with in vivo reflectance confocal microscopy.","authors":"Giulia Greta Dradi, Reyes Gamo Villegas, María Uxmal Floristán Murzubal, Fernando Pinedo Moraleda, Claudia Sarró Fuente, José Luis López Estebaranz","doi":"10.1684/ejd.2024.4747","DOIUrl":"https://doi.org/10.1684/ejd.2024.4747","url":null,"abstract":"<p><p>Lentigo maligna (LM) often poses a diagnostic challenge due to its clinical and dermoscopic mimicry of benign lesions, leading to delayed diagnosis. Focal areas of reticular disruption have been described as one of the earliest dermoscopic signs observed. To describe a novel dermoscopic sign in LM, namely the presence of a parallel pigmented network. Case series of 22 histopathologically-proven LM and lentigo maligna melanoma (LMM), diagnosed between 2018 and 2023, at a tertiary centre. All lesions showed a parallel network upon dermoscopy, in the form of parallel reticular lines, light or dark brown in colour, not emanating from the follicle, with an asymmetrical distribution. Reflectance confocal microscopy (RCM) images were reviewed to correlate these areas. The median age of patients was 73 years old. The majority of lesions were in situ (91%) and extrafacial (82%). Lesions showed minimal signs of atypia other than a parallel network and mostly focal erased areas (100%), followed by perifollicular linear projections (18%) and asymmetrical follicular pigmentation (18%). On RCM, focally areas correlated with atypical junctional thickenings distributed in a parallel fashion (100%) and mitochondria-like structures (23%). Most cases (88%) showed atypical cells in the epidermis, mostly in the form of isolated dendritic cells (41%). Parallel network emerges as a potential dermoscopic sign associated with LM. We hypothesize that in early stages of LM transformation, disruption of the reticular network manifests as parallel lines and/or radial perifollicular lines. Validation with larger studies is warranted.</p>","PeriodicalId":11968,"journal":{"name":"European Journal of Dermatology","volume":"34 5","pages":"490-496"},"PeriodicalIF":2.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142716021","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Psoriasis induced at the injection sites of interferon beta in a patient with multiple sclerosis. 一名多发性硬化症患者注射干扰素 beta 的部位诱发牛皮癣。
IF 2 4区 医学
European Journal of Dermatology Pub Date : 2024-10-01 DOI: 10.1684/ejd.2024.4772
Chang-Yu Hsieh, Tsen-Fang Tsai
{"title":"Psoriasis induced at the injection sites of interferon beta in a patient with multiple sclerosis.","authors":"Chang-Yu Hsieh, Tsen-Fang Tsai","doi":"10.1684/ejd.2024.4772","DOIUrl":"https://doi.org/10.1684/ejd.2024.4772","url":null,"abstract":"","PeriodicalId":11968,"journal":{"name":"European Journal of Dermatology","volume":"34 5","pages":"554-555"},"PeriodicalIF":2.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142716024","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
sQUIZ your knowledge! An ulcerated and friable plaque on the leg of a middle-aged woman. 测验您的知识！一位中年妇女腿上的溃疡和易碎斑块。
IF 2 4区 医学
European Journal of Dermatology Pub Date : 2024-10-01 DOI: 10.1684/ejd.2024.4779
Ana Serrano Ordóñez, Alejandro Arroyo Córdoba, Alexandra Perea Polak
{"title":"sQUIZ your knowledge! An ulcerated and friable plaque on the leg of a middle-aged woman.","authors":"Ana Serrano Ordóñez, Alejandro Arroyo Córdoba, Alexandra Perea Polak","doi":"10.1684/ejd.2024.4779","DOIUrl":"https://doi.org/10.1684/ejd.2024.4779","url":null,"abstract":"","PeriodicalId":11968,"journal":{"name":"European Journal of Dermatology","volume":"34 5","pages":"576-577"},"PeriodicalIF":2.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142716030","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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