European Journal of Dermatology最新文献_第10页

Complete therapeutic response to upadacitinib as a continued treatment for alopecia areata universalis. upadacitinib作为普遍斑秃持续治疗的完全治疗反应。

IF 2 4区医学

European Journal of Dermatology Pub Date : 2025-04-01 DOI: 10.1684/ejd.2025.4862

Gustavo U Machado, Marina S Silverio, Gleison V Duarte, Paulo Rl Machado, Audrey Nosbaum

引用次数: 0

sQuiz your knowledge! A unilateral swollen lesion of the hand following an insect bite. 测试你的知识！被昆虫叮咬后手部单侧肿胀的损伤。

IF 2 4区医学

European Journal of Dermatology Pub Date : 2025-02-01 DOI: 10.1684/ejd.2025.4839

Nour El Imene Ouni, Maha Lahouel, Mohamed Denguezli

引用次数: 0

A case of systemic sclerosis following administration of pembrolizumab for brain metastasis of breast cancer. 派姆单抗治疗乳腺癌脑转移后发生系统性硬化症1例。

IF 2 4区医学

European Journal of Dermatology Pub Date : 2025-02-01 DOI: 10.1684/ejd.2025.4851

Mina Hashimoto, Tomomitsu Miyagaki, Takafumi Kadono

引用次数: 0

Anti-SAE antibody-positive dermatomyositis with erythroderma. 抗sae抗体阳性皮肌炎伴红皮病。

IF 2 4区医学

European Journal of Dermatology Pub Date : 2025-02-01 DOI: 10.1684/ejd.2025.4833

Azusa Kobayashi, Naohiko Aozasa, Yuki Shiina, Masakazu Okabe, Natsumi Fushida, Takashi Matsushita, Koichiro Nakamura, Yuichiro Tsunemi

引用次数: 0

Home anti-PD1 immunotherapy for melanoma: results of a patient and nursing satisfaction survey. 家庭抗pd1免疫疗法治疗黑色素瘤：患者及护理满意度调查结果

IF 2 4区医学

European Journal of Dermatology Pub Date : 2025-02-01 DOI: 10.1684/ejd.2025.4814

Thu Thao Truong, Marie Lapassat, Aude Belbezier, Marie-Thérèse Leccia, Stéphane Mouret, Aude Lemoigne, Julie Charles, Sabiha Trabelsi

{"title":"Home anti-PD1 immunotherapy for melanoma: results of a patient and nursing satisfaction survey.","authors":"Thu Thao Truong, Marie Lapassat, Aude Belbezier, Marie-Thérèse Leccia, Stéphane Mouret, Aude Lemoigne, Julie Charles, Sabiha Trabelsi","doi":"10.1684/ejd.2025.4814","DOIUrl":"10.1684/ejd.2025.4814","url":null,"abstract":"Immunotherapies have revolutionized the management of melanoma, particularly anti-PD1 agents. While the COVID-19 pandemic disrupted the organization of day hospital care, this health context motivated the implementation of home immunotherapy. We evaluated the safety of home immunotherapy and the satisfaction of patients receiving anti-PD1 agents at home for melanoma. All patients with advanced melanoma, followed at Grenoble University Hospital between June 2020 and August 2021 and receiving a home infusion of anti-PD1 treatment, were included. A satisfaction questionnaire was distributed to patients and to physicians and nurses in charge of these patients. Twenty-six patients were included. No serious adverse events occurred. Of these 26 patients, 25 (96%) were satisfied with their home care. The main strengths were time savings and reduced travel. The main potential issue, according to patients, was the nurses' lack of experience. The physicians (n=5) and private nurses (n=9) were also satisfied overall (100% and 44% respectively). The main issue for nurses was the lack of training in melanoma (78%). Home-based anti-PD1 immunotherapy for advanced melanoma is safe, well accepted and welcomed by patients and caregivers. One of the difficulties raised by homecare was the lack of training of private practice nurses in pathology, which underlines the importance of developing a care pathway.","PeriodicalId":11968,"journal":{"name":"European Journal of Dermatology","volume":"35 1","pages":"31-37"},"PeriodicalIF":2.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143662876","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Four years of study by an expert group on truncal acne: where are we now? 一个专家组对躯干痤疮的四年研究：我们现在在哪里？

IF 2 4区医学

European Journal of Dermatology Pub Date : 2025-02-01 DOI: 10.1684/ejd.2025.4809

Marie Thérèse Leccia, Jean Paul Claudel, Fabienne Ballanger, Nicole Auffret, Brigitte Dreno

{"title":"Four years of study by an expert group on truncal acne: where are we now?","authors":"Marie Thérèse Leccia, Jean Paul Claudel, Fabienne Ballanger, Nicole Auffret, Brigitte Dreno","doi":"10.1684/ejd.2025.4809","DOIUrl":"10.1684/ejd.2025.4809","url":null,"abstract":"Until recently, interest in truncal acne has been low, resulting in only a small amount of published data, focussing mainly on therapeutic options previously developed for facial acne. This report provides a summary of the work carried out since 2020 on truncal acne by a group of experts in acne. The expert group reviewed their own studies as well as more recently published articles on truncal acne and its management in daily clinical practice. The experts produced four publications dating from 2020 onwards on the different issues regarding truncal acne, ranging from physiopathology, aetiology, assessment of severity, and treatment to quality of life in adolescents. Since these studies began, six other publications on truncal acne have been published. Of these, four concern investigative data on clascoterone, sarecyline and a dermocosmetic; one is a review on the management of truncal acne and acne scars, and one is an update of the American acne treatment guidelines. Moreover, the authors confirmed that interest in truncal acne has significantly increased over recent years and that new treatment options for truncal acne are either being developed or are already available. Truncal acne has significantly gained interest over recent years, and novel assessment tools and treatments are available to manage this condition efficiently. However, international treatment guidelines require updating, considering the importance of truncal acne.","PeriodicalId":11968,"journal":{"name":"European Journal of Dermatology","volume":"35 1","pages":"25-30"},"PeriodicalIF":2.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143662869","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Skin condition and barrier function in individuals with a history of atopic dermatitis. 有特应性皮炎病史的个体的皮肤状况和屏障功能。

IF 2 4区医学

European Journal of Dermatology Pub Date : 2025-02-01 DOI: 10.1684/ejd.2025.4810

Eunbyul Cho, Junghwa Kim, Baegon Kang, Kwanghyeon Liu, Changhui Cho, Eunyoung Lee, Jaehyoun Ha, Kyung-Min Lim

{"title":"Skin condition and barrier function in individuals with a history of atopic dermatitis.","authors":"Eunbyul Cho, Junghwa Kim, Baegon Kang, Kwanghyeon Liu, Changhui Cho, Eunyoung Lee, Jaehyoun Ha, Kyung-Min Lim","doi":"10.1684/ejd.2025.4810","DOIUrl":"10.1684/ejd.2025.4810","url":null,"abstract":"Atopic dermatitis (AD) is a chronic inflammatory skin condition characterized by a multifaceted interplay of factors including skin barrier dysfunction, immunoregulation, environmental influences, and potential infectious agents. While AD lesions commonly ameliorate or resolve with age, individuals with a history of AD often retain susceptibility to irritants even after symptom remission. We aimed to investigate skin condition and barrier function of volunteers with a history of AD in order to obtain insight into their skin care. A cohort comprising 62 adults participated in this study; 30 subjects with a history of AD and 32 in the control group. Assessment parameters included hydration level, trans-epidermal water loss (TEWL), skin barrier recovery following stratum corneum damage induced by tape-stripping, skin roughness, blood flow, and skin sensitivity. Additionally, the levels of natural moisturizing factor (NMF) and ceramides of inner forearm skin were analysed. No significant differences were observed regarding hydration level, sensitivity score, and TEWL on the cheek area between the AD history and control group. Similarly, comparisons of hydration level, NMF level, ceramide level, and blood flow on the inner forearm skin did not reveal significant differences between the AD history and control group. However, the AD history group displayed significantly higher TEWL values, delayed skin barrier recovery following stratum corneum damage, and skin roughness on the inner forearm skin. Individuals with a history of AD, even after symptom resolution and displaying a normal appearance, present compromised skin barrier function and resistance to barrier damage.","PeriodicalId":11968,"journal":{"name":"European Journal of Dermatology","volume":"35 1","pages":"16-24"},"PeriodicalIF":2.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143662923","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

sQUIZ your knowledge! Ulcers on the red ink of tattoos. 测试你的知识！红墨水上的溃疡。

IF 2 4区医学

European Journal of Dermatology Pub Date : 2025-02-01 DOI: 10.1684/ejd.2025.4838

Clara Valente, Maria Cristina Fialho, Bruno Duarte

引用次数: 0

IF 2 4区医学

European Journal of Dermatology Pub Date : 2025-02-01 DOI: 10.1684/ejd.2025.4811

Lan Guo, Biao Song, Chao Wu, Hong-Zhong Jin

{"title":"Platelet-related parameters as systemic markers of erythrodermic psoriasis.","authors":"Lan Guo, Biao Song, Chao Wu, Hong-Zhong Jin","doi":"10.1684/ejd.2025.4811","DOIUrl":"10.1684/ejd.2025.4811","url":null,"abstract":"Erythrodermic psoriasis (EP) is a severe disease with systemic inflammation and complications. The pathogenesis remains largely unknown. Recent studies have shown that platelets play important roles in psoriasis, but the association between platelets and EP is unclear. This study aimed to analyse, for the first time, the clinical significance of platelet-related parameters in EP patients. We retrospectively investigated the clinical and laboratory data of 92 EP patients, 93 sex/age-matched psoriasis vulgaris (PsV) patients, and 93 matched healthy controls (HC). The platelet-related parameters, including platelet count, plateletcrit (PCT), mean platelet volume (MPV), platelet distribution width (PDW), platelet large cell ratio (P-LCR) and platelet/lymphocyte ratio (PLR), were compared between the three groups. Associations between these parameters and disease severity, and between platelet count and complications of EP were analysed, and compared before and after treatment. Platelet count, PCT, and PLR were significantly elevated in EP compared with PsV and HC (p < 0.001). MPV was higher in EP patients compared with HC (p < 0.001). Based on ROC analyses, moderate-to-severe and mild EP could be clearly distinguished based on platelet count and PCT. In terms of complications, a platelet count level ≥ 270 × 109/L was associated with a significantly higher rate of hypoalbuminemia and abnormal liver function. After treatment, platelet count, PCT, and PLR were significantly reduced. Our data show, for the first time, a significant alteration of platelet-related parameters in EP patients, indicating a strong association between platelets and EP. Platelet count and PCT may be used as cost-effective and simple tools to serve as systemic markers for EP.","PeriodicalId":11968,"journal":{"name":"European Journal of Dermatology","volume":"35 1","pages":"9-15"},"PeriodicalIF":2.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143662904","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A case of infantile hemangioma with minimal or arrested growth: clinical differentiation and efficacy of propranolol therapy. 婴儿血管瘤生长缓慢或停止1例：临床鉴别和心得安治疗的疗效。

IF 2 4区医学

European Journal of Dermatology Pub Date : 2025-02-01 DOI: 10.1684/ejd.2025.4817

Momo Sato, Natsumi Hama, Mai Higuchi, Haruna Kimura, Yoshihiro Sasaki, Fumihiro Goto, Riichiro Abe

引用次数: 0