European Journal of Cancer Care最新文献

{"title":"Investigating Fatigue and Its Relationship to Quality of Life and Pruritus in Cutaneous T-Cell Lymphoma","authors":"Deniz Özistanbullu,&nbsp;Stephan Hackenberg,&nbsp;Johannes Kleemann,&nbsp;Stefan Kippenberger,&nbsp;Daniela Lenders,&nbsp;Sabine Tratzmiller,&nbsp;Roland Kaufmann,&nbsp;Claus-Detlev Klemke,&nbsp;Markus Meissner,&nbsp;Manuel Jäger","doi":"10.1155/2023/5017551","DOIUrl":"10.1155/2023/5017551","url":null,"abstract":"<div>\u0000 <p>Cancer-related fatigue as a morbid state of physical, emotional, and mental exhaustion influencing everyday life is an important yet poorly investigated symptom in patients with cutaneous T-cell lymphomas. The aim of this study was to evaluate the prevalence of and the association between pruritus, quality of life, and fatigue in patients with cutaneous T-cell lymphomas. Mycosis fungoides and Sézary syndrome patients were invited to complete the Functional Assessment of Cancer Therapy-General (FACT-G) and the Functional Assessment of Chronic Illness Therapy-Fatigue (FACIT-Fatigue) subscale questionnaire. Pruritus was assessed using the peak pruritus numeric rating scale. Half of the 38 recruited patients reported fatigue. 13 patients (34%) suffered from severe fatigue. The median (interquartile range) FACIT-Fatigue subscale score was 35.5 (25.75–43). The advanced disease stage was associated with more severe fatigue and a poorer quality of life. The FACIT-Fatigue subscale score was significantly correlated with quality of life (<i>r</i> = 0.8 and <i>P</i> &lt; 0.0001). More than 80% of patients reported pruritus. There was no correlation between pruritus and fatigue (<i>r</i> = −0.19 and <i>P</i> = 0.26). All in all, fatigue is a common symptom of cutaneous T-cell lymphomas in early and advanced stage disease and has a strongly negative effect on cutaneous T-cell lymphoma patients’ quality of life.</p>\u0000 </div>","PeriodicalId":11953,"journal":{"name":"European Journal of Cancer Care","volume":"2023 1","pages":""},"PeriodicalIF":1.8,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/2023/5017551","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48270341","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Nature and Quality of Support from Informal Networks for Informal Caregivers of Low-Grade Glioma Patients: A Qualitative Analysis within the Ways Ahead Study","authors":"Andrew James Murrell,&nbsp;Ben Rimmer,&nbsp;Lizzie Dutton,&nbsp;Joanne Lewis,&nbsp;Richéal Burns,&nbsp;Pamela Gallagher,&nbsp;Sophie Williams,&nbsp;Vera Araújo-Soares,&nbsp;Tracy Finch,&nbsp;Linda Sharp","doi":"10.1155/2023/4149412","DOIUrl":"10.1155/2023/4149412","url":null,"abstract":"<div>\u0000 <p><i>Objective</i>. Those closest to the patients with low-grade glioma (LGG) often become informal caregivers (ICs). Caregiving demands can impact ICs’ wellbeing, meaning they themselves may require support. We explored the nature and quality of support from informal networks for ICs of LGG patients. <i>Methods</i>. In this cross-sectional qualitative study, semistructured interviews were conducted with individuals from the United Kingdom who currently, or in the past five years, informally cared for someone diagnosed with an LGG. Interviews explored ICs’ experiences of receiving support from informal networks. Thematic analysis was undertaken. <i>Results</i>. Nineteen ICs were interviewed (mean age 54.6 years; 5 males, 14 females). ICs received multiple forms of support from their informal networks: emotional (e.g., “opportunities to talk”), instrumental (e.g., “opportunities for relief”), information (e.g., “information from network contacts”), and appraisal (e.g., “comparisons with similar others”). Networks comprised strong/familiar (e.g., close friends) and weaker/unfamiliar (e.g., other ICs) ties. Supportive networks were perceived to help protect ICs’ wellbeing. Participants perceived challenges such as poor understanding and unsolicited advice to weaken the quality of support. <i>Conclusion</i>. Informal networks can provide wide-ranging support for ICs of the LGG patients. Different supports may be sought or provided from different contacts, highlighting the importance and value of extended networks.</p>\u0000 </div>","PeriodicalId":11953,"journal":{"name":"European Journal of Cancer Care","volume":"2023 1","pages":""},"PeriodicalIF":1.8,"publicationDate":"2023-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/2023/4149412","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45309906","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Multiple Levels of Influence on Lifestyle Behaviors among Cancer Survivors in Racial and Ethnic Minority Groups: A Systematic Review","authors":"Dalnim Cho,&nbsp;Seokhun Kim,&nbsp;Scherezade K. Mama,&nbsp;Maria C. Swartz,&nbsp;Yimin Geng,&nbsp;Qian Lu","doi":"10.1155/2023/8504968","DOIUrl":"10.1155/2023/8504968","url":null,"abstract":"<div>\u0000 <p><i>Objective</i>. This systematic review aimed to provide a critical summary of studies of physical activity (PA) and diet among racial/ethnic minority cancer survivors. Guided by the socio-ecological model, we identified factors across multiple levels—individual, family/social support, provider/team, and organization/local community/policy environment—that affect PA and diet among racial/ethnic minority survivors. <i>Methods</i>. We searched the Ovid MEDLINE, EBSCO CINAHL, Ovid PsycInfo, and PubMed databases. We extracted the behavior of focus (i.e., PA and diet), cancer type, race/ethnicity, and the level(s) of influence (and the corresponding factor(s)), and each eligible study investigated individual (e.g., demographic characteristics, psychological factors), family/social support, provider/team (e.g., healthcare provider recommendations), and organization/local community/policy environment (e.g., neighborhood/social environment). <i>Results</i>. Of 1,603 studies identified, 23 unique studies were eligible. Most studies included breast cancer survivors (<i>n</i> = 19) and Black survivors (<i>n</i> = 13). Seventeen studies assessed associations between PA and factors at the level of the individual (16 studies), family/social support (two studies), provider/team (one study), or organization/local community/policy environment (four studies). Eleven studies assessed associations between diet and factors at the level of the individual (11 studies), family/social support (two studies), provider/team (one study), or organization/local community/policy environment (two studies). Only five studies simultaneously investigated factors across multiple levels. Most demographic and cancer-related factors were not associated with PA or diet. Overall, factors from social-cognitive theories (e.g., self-efficacy) were positively associated with PA. Less consensus was found regarding diet because fewer studies existed, and they also investigated a diverse range of eating behaviors. <i>Conclusions</i>. There is a critical need for studies of PA and diet that investigate multiple levels of influence particularly for Asian American survivors, male survivors, and cancers other than breast cancer. Social-cognitive theories may help guide the designing of multilevel PA interventions for racial/ethnic minority survivors. Studies assessing overall eating quality or adherence to dietary guidelines are needed.</p>\u0000 </div>","PeriodicalId":11953,"journal":{"name":"European Journal of Cancer Care","volume":"2023 1","pages":""},"PeriodicalIF":1.8,"publicationDate":"2023-07-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11611251/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41603471","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Patient Experiences of a Telehealth Multidisciplinary Cancer Rehabilitation Programme: Qualitative Findings from the ReStOre@Home Feasibility Study","authors":"A. O’Brien,&nbsp;L. Brennan,&nbsp;L. O’Neill,&nbsp;D. Connolly,&nbsp;E. Guinan,&nbsp;J. V. Reynolds,&nbsp;J. Hussey","doi":"10.1155/2023/7998022","DOIUrl":"10.1155/2023/7998022","url":null,"abstract":"<div>\u0000 <p><i>Purpose</i>. Multidisciplinary rehabilitation programmes providing exercise, nutrition support, education, and peer support can effectively meet the rehabilitation needs of upper gastrointestinal (UGI) cancer survivors. This study aimed to explore the experiences of participants who engaged in a telehealth, multidisciplinary rehabilitation programme for UGI cancer survivors. <i>Methods</i>. This single-arm feasibility study recruited participants who completed curative treatment for UGI cancer. Participants (<i>n</i> = 10, male = 9) aged 58–76 years were 5–17 months postsurgery. A 12-week telehealth rehabilitation programme was delivered via video call, consisting of group resistance training, remotely monitored aerobic training, 1 : 1 dietary counselling, 1 : 1 physiotherapy support, and group education sessions. Independent researchers conducted semistructured interviews at postintervention assessments. Transcripts were analysed using reflexive thematic analysis (RTA). <i>Results</i>. RTA of participant transcripts generated three overarching themes: (1) ReStOre@Home impacted psychosocial and physical needs by addressing a broad and meaningful gap in services, (2) paving a pathway towards prosperity, and (3) contrasting experiences with using technology. Participants’ preferences and recommendations for future telehealth programmes were discussed. <i>Conclusions</i>. A telehealth multidisciplinary rehabilitation programme supported participants in physical and psychosocial recovery. Qualitative analysis identified an important ongoing need for some in-person care and provided detailed insights into participant experiences during telehealth-delivered rehabilitation.</p>\u0000 </div>","PeriodicalId":11953,"journal":{"name":"European Journal of Cancer Care","volume":"2023 1","pages":""},"PeriodicalIF":1.8,"publicationDate":"2023-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/2023/7998022","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46159609","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence of Cachexia in Cancer Patients","authors":"Cristian Orellana López,&nbsp;Jose Leyton Estéfane,&nbsp;Miguel Ramos Rosales,&nbsp;Claudio Vásquez Ramirez,&nbsp;Claudia Manriquez Arriagada,&nbsp;Josep M. Argilés,&nbsp;Francisco J. López-Soriano,&nbsp;Francisco Ortega González,&nbsp;Nicolás Yañez,&nbsp;Silvia Busquets","doi":"10.1155/2023/5743872","DOIUrl":"10.1155/2023/5743872","url":null,"abstract":"<div>\u0000 <p><i>Introduction</i>. Cachexia is a syndrome characterized by the loss of musculoskeletal mass, with or without adipose mass, which cannot be reversed by nutritional support. In Chile, there are no data on cachexia in cancer patients that allows for decision making on better interdisciplinary management. In this study, the prevalence of cachexia in inpatient and outpatient cancer patients was investigated. <i>Methods</i>. An observational, descriptive, and cross-sectional study was carried out. Eighty-six inpatients and outpatients were evaluated. Cachexia was evaluated by applying the miniCASCO tool, its weight by bioimpedance, and inflammation by blood parameters. Comparisons and correlations were made considering <i>p</i> &lt; 0.05 as the threshold for statistical significance. <i>Results</i>. Forty patients met the inclusion criteria, 35% were men and 65% were women. In all, 27.5% of patients had cachexia secondary to cancer. Of the total number of patients with the syndrome, approximately 45.4% had mild cachexia, 36.3% had severe cachexia, and 18.1% had moderate cachexia. In addition, there was a significant positive correlation (<i>p</i> = 0.0150) and moderately strong (<i>r</i> = 0.7209) match between the final scores and the stage of cancer. <i>Conclusion</i>. The prevalence of cachectic patients is reported for the first time through the application of the miniCASCO tool. A moderate positive match was detected between the final miniCASCO score and the stages of cancer patients. Finally, an early discovery of cachexia would allow therapeutic interventions aimed at improving the prognosis of cancer patients.</p>\u0000 </div>","PeriodicalId":11953,"journal":{"name":"European Journal of Cancer Care","volume":"2023 1","pages":""},"PeriodicalIF":1.8,"publicationDate":"2023-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/2023/5743872","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43237289","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of CCR2-V64I on the Susceptibility of Patients to Cancer","authors":"Xue-Jiao Lu,&nbsp;Lin Li,&nbsp;Xin-Ying Zhou","doi":"10.1155/2023/7630422","DOIUrl":"10.1155/2023/7630422","url":null,"abstract":"<div>\u0000 <p><i>Background</i>. Results from the studies investigating the impact of CC chemokine receptor 2 (CCR2) polymorphism on the risk of cancers are diverse. An updated meta-analysis was conducted to access the relationship between cancer risk and CCR2-V64I polymorphism. <i>Methods</i>. We performed a meta-analysis using STATA 11.0 based on a comprehensive retrieval in WanFang Data, PubMed, China National Knowledge Infrastructure, EMBASE, and Web of Science databases up to January 20, 2023. <i>Results</i>. We included 23 studies in our analysis. Overall, we found CCR2-V64I polymorphism was remarkably related to cancer risk (OR = 1.39, 95% CI = 1.14–1.70, and <i>P</i> = 0.001 for A vs <i>G</i>; OR = 1.87, 95% CI = 1.30–2.70, and <i>P</i> = 0.001 for AA vs GG; OR = 1.35, 95% CI = 1.03–1.78, and <i>P</i> = 0.032 for GA vs GG; OR = 1.45, 95% CI = 1.11–1.90, and <i>P</i> = 0.006 for AA + GA vs GG; OR = 1.69, 95% CI = 1.20–2.37, and <i>P</i> = 0.003 for AA vs GA + GG). In the ethnicity subgroup analysis, the relevancy between CCR2-V64I polymorphism and an increased cancer risk was discovered among Asians (OR = 1.57, 95% CI = 1.30–1.91, and <i>P</i> &lt; 0.001 for A vs <i>G</i>; OR = 2.30, 95% CI = 1.64–3.24, and <i>P</i> &lt; 0.001 for AA vs GG; OR = 1.35, 95% CI = 1.10–1.67, and <i>P</i> = 0.005 for GA vs GG; OR = 1.52, 95% CI = 1.25–1.87, and <i>P</i> &lt; 0.001 for AA + GA vs GG; OR = 2.21, 95% CI = 1.58–3.08, and <i>P</i> &lt; 0.001 for AA vs GA + GG). In addition, the subgroup analysis in the light of cancer types demonstrated that CCR2-V64I polymorphism was strongly correlated with bladder cancer (OR = 3.04, 95% CI = 1.09–8.45, and <i>P</i> = 0.033 for AA vs GG; OR = 2.84, 95% CI = 1.07–7.09, and <i>P</i> = 0.035 for AA vs GA + GG) and oral cancer (OR = 1.83, 95% CI = 1.39-2.42, and <i>P</i> &lt; 0.001 for A vs <i>G</i>; OR = 2.04, 95% CI = 1.47–2.85, and <i>P</i> &lt; 0.001 for GA vs GG; OR = 2.03, 95% CI = 1.48–2.79, and <i>P</i> &lt; 0.001 for AA + GA vs GG). <i>Conclusion</i>. The meta-analysis suggested that CCR2-V64I polymorphism might be a high-risk factor for cancers among Asians, especially for bladder and oral cancers.</p>\u0000 </div>","PeriodicalId":11953,"journal":{"name":"European Journal of Cancer Care","volume":"2023 1","pages":""},"PeriodicalIF":1.8,"publicationDate":"2023-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/2023/7630422","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43185302","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Development of Ambulatory Cancer Care in the UK: A Scoping Review of the Literature","authors":"Alison Finch,&nbsp;Silvie Cooper,&nbsp;Rosalind Raine,&nbsp;Rachel M. Taylor,&nbsp;Faith Gibson","doi":"10.1155/2023/4589362","DOIUrl":"10.1155/2023/4589362","url":null,"abstract":"<div>\u0000 <p><i>Introduction</i>. Ambulatory Care (AC), where patients receive inpatient cancer treatment on an outpatient basis, was introduced into the United Kingdom (UK) National Health Service (NHS) in 2004. Although now well established within some services, the development of AC across the NHS is yet to be described. We report findings of a scoping review that set out to understand the provenance of the clinical pathway, whilst exploring drivers for the development of AC in the UK. <i>Methods</i>. Using scoping review methods, database citation, and grey literature, searches were undertaken to map the storyline of AC’s development internationally. The Joanna Briggs Institute guidance was followed; this included consultation with six professionals considered critical to the development of AC. <i>Results.</i> From the 57 records identified between 1979 and 2022, four domains were identified through a narrative synthesis that reflected the following drivers for AC: financial; optimisation of bed capacity; advances in technology and supportive care; and professional motivation to improve patient experience. <i>Conclusion.</i> We report the first descriptive analysis of the international development of AC, locating the UK cancer service within its commissioning, operational, and philosophical foundations. The review additionally highlights limited research exploring the experience of the AC model from the patients’ perspective.</p>\u0000 </div>","PeriodicalId":11953,"journal":{"name":"European Journal of Cancer Care","volume":"2023 1","pages":""},"PeriodicalIF":1.8,"publicationDate":"2023-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/2023/4589362","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46934640","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Erratum to “Multidisciplinary Preventive Intervention for Breast Cancer-Related Lymphedema: An International Consensus”","authors":"Patricia Martínez-Jaimez,&nbsp;Pilar Fuster Linares,&nbsp;Neil Piller,&nbsp;Jaume Masia,&nbsp;Takumi Yamamoto,&nbsp;Luis López-Montoya,&nbsp;Cristina Monforte-Royo","doi":"10.1155/2023/9897040","DOIUrl":"https://doi.org/10.1155/2023/9897040","url":null,"abstract":"<p>In the article titled “Multidisciplinary Preventive Intervention for Breast Cancer-Related Lymphedema: An International Consensus” [<span>1</span>], an Acknowledgments section was omitted in error. The Acknowledgments section is as follows.</p><p>The error was introduced during the production process of the article, and Hindawi apologises for causing this error in the article.</p>","PeriodicalId":11953,"journal":{"name":"European Journal of Cancer Care","volume":"2023 1","pages":""},"PeriodicalIF":1.8,"publicationDate":"2023-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/2023/9897040","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143252509","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Multimodal Exercise in Older Patients with Advanced Pancreatic Cancer Undergoing First-Line Chemotherapy: A Case Series Examining Feasibility and Preliminary Efficacy","authors":"Hao Luo,&nbsp;Daniel A. Galvão,&nbsp;Robert U. Newton,&nbsp;Colin I. Tang,&nbsp;Nigel Spry,&nbsp;Dennis R. Taaffe","doi":"10.1155/2023/1179848","DOIUrl":"10.1155/2023/1179848","url":null,"abstract":"<div>\u0000 <p><i>Purpose</i>. Exercise is emerging as an adjunct therapy to cancer treatment; however, its role in older patients with advanced pancreatic cancer undergoing first-line chemotherapy is unclear. The aim of this study was to primarily provide evidence on feasibility with an exploratory examination of the initial efficacy of exercise in this clinical setting. <i>Materials and Methods</i>. Six patients aged 60–75 years with <i>de novo</i> or recurrent advanced pancreatic cancer undergoing first-line chemotherapy consented to participate in twice-weekly exercise that included resistance and aerobic training and boxing-related activities for up to 12 weeks. Patients were monitored for attendance, adherence, and adverse events. Body composition, muscle strength, functional ability, patient-reported outcome measures, and patient-reported experience measures were assessed at baseline and/or postintervention. <i>Results</i>. Of the 6 patients, 1 withdrew after baseline testing and 5 attended 42%–95% of planned sessions and adhered to 28%–83% of the prescribed exercise. There were no serious exercise-emergent adverse events. All 5 patients increased or maintained lean mass (0.1%–4.4%) and 4 reduced fat mass (−0.4%–−8.6%). Improvements were observed in 4 or all 5 patients for muscle strength (7.1%–75%), 5 times sit-to-stand (1.3%–21.4%), 6-m backward walk (16.5%–35.8%), and patient-reported outcomes. Furthermore, all patients perceived exercise as very helpful in managing their cancer and expressed a strong willingness to continue exercise in the future. <i>Conclusion</i>. A multimodal exercise program appears feasible with potential physical and psychological benefits for older patients with advanced pancreatic cancer undergoing first-line chemotherapy. Further research including a larger sample size is warranted.</p>\u0000 </div>","PeriodicalId":11953,"journal":{"name":"European Journal of Cancer Care","volume":"2023 1","pages":""},"PeriodicalIF":1.8,"publicationDate":"2023-05-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/2023/1179848","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48289407","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prognostic Analysis on Different Tumor Sizes for 14634 Hepatocellular Carcinoma Patients","authors":"Zilin Chen,&nbsp;He Zheng,&nbsp;Wen Zeng,&nbsp;Mengyao Liu,&nbsp;Yong Chen","doi":"10.1155/2023/1106975","DOIUrl":"10.1155/2023/1106975","url":null,"abstract":"<div>\u0000 <p><i>Aim</i>. This study investigated the effect of tumor size and other factors on the survival and prognosis of hepatocellular carcinoma (HCC). <i>Methods</i>. All HCC populations based on the National Cancer Institute’s SEER database to receive from 2010 to 2016 were employed in the study. <i>Results</i>. This study enrolled a total of 14,634 HCC. Among them, 1,686 patients had tumors ≤ 2 cm, 6,169 patients had tumors 2–5 cm, and 6,779 patients had tumors &gt; 5 cm. The results using univariate analysis showed that all factors were significant prognostic factors for overall survival and specific survival. Patients with tumor size ≤ 2 cm were more likely to survive, while patients with tumor size &gt; 5 cm had a lower survival rate. Patients who had surgery or surgery plus chemotherapy had a higher chance of survival in stages I-II, and the survival rate declined smoothly during the 80 months. The change rate of the mortality rate increased rapidly during the period of 1–12 cm; afterwards, the mortality rate’s HR was basically and smoothly maintained at a high level. <i>Conclusions</i>. Tumor size was positively correlated with the mortality rate of HCC. Survival rates were greater in patients with tumors ≤ 2 cm who underwent surgery or surgery plus chemotherapy. Patients with HCC in the early stage had a higher survival probability particularly when they had experienced surgery or surgery plus chemotherapy.</p>\u0000 </div>","PeriodicalId":11953,"journal":{"name":"European Journal of Cancer Care","volume":"2023 1","pages":""},"PeriodicalIF":1.8,"publicationDate":"2023-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/2023/1106975","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"64789715","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}