European Journal of Cancer Care最新文献

{"title":"Patients’ Experiences in a Newly Established Clinic for Late Complications after Colorectal and Anal Cancer Treatment: A Qualitative Study","authors":"Birthe Thing Oggesen,&nbsp;Momena Akbar,&nbsp;Marie Louise Sjødin Hamberg,&nbsp;Thordis Thomsen,&nbsp;Anne Kjaergaard Danielsen,&nbsp;Jacob Rosenberg","doi":"10.1155/2023/9924560","DOIUrl":"10.1155/2023/9924560","url":null,"abstract":"<div>\u0000 <p><i>Purpose</i>. Treatment of late complications is not systematically provided in Denmark. We therefore established a clinic to treat patients’ late complications. With this study, we wanted to explore patients’ experiences with treatment and care in such a clinic, including their recommendations for the future organization and structure of the clinic. <i>Methods</i>. We conducted a qualitative semistructured interview study with 14 patients who had attended a late complication clinic after treatment for colorectal or anal cancer. We used a descriptive approach to describe the patients’ experiences. <i>Results</i>. We found four major categories: (1) benefitting from the late complication clinic, (2) confusion about which clinic they attended, (3) recommendations for the future of the clinic, and (4) preparation and delivery of the consultations. Patients benefitted from attending the late complication clinic, and some experienced complete relief from symptoms. Others did not, but they gained hope that they might be able to receive treatment in the future. Patients wished for more information about late complications, preferring that the most common symptoms were described along with patient-friendly treatment options. The patients were satisfied with telephone consultations, as they were easy to fit into a daily schedule, and patients found it easy to express themselves openly. <i>Conclusions</i>. Patients were satisfied with the late complication clinic as they felt it gave them a safety net. For the future, patients recommended provision of more information about late complications and possible treatments.</p>\u0000 </div>","PeriodicalId":11953,"journal":{"name":"European Journal of Cancer Care","volume":"2023 1","pages":""},"PeriodicalIF":1.8,"publicationDate":"2023-05-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/2023/9924560","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135861521","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Postoperative Recovery Course of Skeletal Muscle Mass in Older Esophageal Cancer Patients","authors":"Tsuyoshi Harada,&nbsp;Tetsuya Tsuji,&nbsp;Noriatsu Tatematsu,&nbsp;Junya Ueno,&nbsp;Yu Koishihara,&nbsp;Nobuko Konishi,&nbsp;Takumi Yanagisawa,&nbsp;Nanako Hijikata,&nbsp;Aiko Ishikawa,&nbsp;Takeo Fujita","doi":"10.1155/2023/6655999","DOIUrl":"10.1155/2023/6655999","url":null,"abstract":"<div>\u0000 <p><i>Purpose</i>. Skeletal muscle mass (SMM) is an important biomarker for health in older cancer patients. However, there is limited information on the recovery course of SMM after esophagectomy in older patients. This study aimed to investigate the recovery course of SMM after esophagectomy and the predictors in older cancer patients. <i>Methods</i>. We conducted a single-center, retrospective cohort study. Esophageal cancer patients who underwent esophagectomy were included. The skeletal muscle mass index (SMI) was calculated using computed tomography images. The loss of SMI at 4 and 12 months after surgery was calculated as [(preoperative − postoperative SMI) ÷ preoperative SMI] × 100%. Nonrecovery was defined as an SMI loss of ≥2% at 12 months after surgery, considering physiological loss with aging. One-way analysis of variance and multivariate logistic regression analysis was used for statistical analysis. <i>Results</i>. A total of 105 older (≥70 years) and 156 nonolder (&lt;70 years) patients were analyzed. Older patients had a significantly larger loss of SMI 4 months (mean: 5.7% vs. 3.1%; <i>p</i> = 0.021) and 12 months (mean: 1.0% vs. −1.4%; <i>p</i> = 0.040) after surgery than nonolder patients. In older patients, the number of patients with nonrecovery of SMI at 12 months after surgery was 55 (52%). In older patients, significant predictors for the nonrecovery of SMI were preoperative sarcopenia (adjusted OR: 0.297; <i>p</i> = 0.012), neoadjuvant chemotherapy (adjusted OR: 0.248; <i>p</i> = 0.015), and loss of SMI 4 months after surgery (per 1%; adjusted OR: 1.076; <i>p</i> = 0.018). <i>Conclusions</i>. It is suggested that older esophageal cancer patients have a larger unmet need for long-term postoperative loss of SMM than nonolder patients. Continuous outpatient rehabilitation, including exercise and nutritional therapy after discharge, which targets improvement in SMM at 4 months, may improve SMI at 12 months after surgery in older esophageal cancer patients.</p>\u0000 </div>","PeriodicalId":11953,"journal":{"name":"European Journal of Cancer Care","volume":"2023 1","pages":""},"PeriodicalIF":1.8,"publicationDate":"2023-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/2023/6655999","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46727501","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Women’s Willingness to Pay for Mammography Screening under Two Medical Information Scenarios","authors":"Shirin Nosratnejad,&nbsp;Shiva Rahmani,&nbsp;Mahmood Yousefi,&nbsp;Maryam Moeeni","doi":"10.1155/2023/3732383","DOIUrl":"10.1155/2023/3732383","url":null,"abstract":"<div>\u0000 <p><i>Objective</i>. Secondary prevention of breast cancer (BC) helps diagnose the disease in the early stages and prevent disease progression. World Health Organization and the American Cancer Society consider early diagnosis as the best way to control BC. Mammography screening is the most sensitive and specific test that can be conducted along with the clinical examination for the early diagnosis of BC. However, like other tests, mammography is not a perfect test. The purpose of the present study is to measure willingness to pay (WTP) for mammography among a sample of women by providing each of them one of two scenarios describing medical information on the test. <i>Methods</i>. 450 women aged 35–55 years were assigned randomly into two groups of equal numbers in a quasi-experimental study conducted in Tabriz city, Iran. Each group was presented with one of the two designed scenarios. First scenario described the basic medical information on mammography as a good test of BC screening. The alternative scenario described some information on potential diagnostic errors of the mammography result alongside basic medical information about this test. The double bounded dichotomous choice method was used to extract women’s WTP for mammography under each scenario. <i>Results</i>. Based on the official currency exchange rate of 37000 IRR/USD, the mean WTP for BC screening with mammography was estimated as 30.5$ in the group receiving basic medical information and 26.8$ in the other group. However, the result of regression analysis revealed receiving information on potential diagnostic errors of mammography result did not lead to significant higher WTP for the test. The WTP for mammography raised significantly among older women, employed women, and those with higher level of education. <i>Conclusion</i>. The result of our study suggests that providing women with information about the potential diagnostic errors of mammography may not be correlated to economic value they give to this test. However, women with different individual status may reveal different economic value on mammography.</p>\u0000 </div>","PeriodicalId":11953,"journal":{"name":"European Journal of Cancer Care","volume":"2023 1","pages":""},"PeriodicalIF":1.8,"publicationDate":"2023-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/2023/3732383","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49045302","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Quality of Life in Caregivers of Patients with Brain Tumours: A Systematic Review and Thematic Analysis","authors":"James Tallant,&nbsp;Lillie Pakzad-Shahabi,&nbsp;Sylvie D. Lambert,&nbsp;Matthew Williams,&nbsp;Mary Wells","doi":"10.1155/2023/2882837","DOIUrl":"10.1155/2023/2882837","url":null,"abstract":"<div>\u0000 <p><i>Objective</i>. (1) Examine QoL of caregivers of patients with brain tumours compared to population norms and other cancer caregiver groups, (2) appraise the content of quantitative QoL outcome measures utilised, and (3) assess to what extent QoL measures used in research align with caregivers’ priorities. <i>Methods</i>. Systematic literature search of studies including caregivers of brain tumour patients using self-completed assessments of QoL. Extracted data from included studies included quantitative QoL outcome data, QoL outcome measures utilised, and the included QoL domains. The impact of brain tumour patient caregiving was assessed by summarising included data comparing brain tumour caregivers to other cancer caregivers and normative population data. QoL measures utilised by the studies and their domains were extracted, coded, and analysed by themes. The rates of investigation by theme were then compared to existing data on caregiver-own preference in relation to QoL. <i>Results</i>. 49 studies, including 57 outcome measures, incorporating a combined 124 QoL domains. Brain tumour caregivers reported lower QoL outcomes than population norms but similar to other cancer caregiver groups. Thematic analysis of QoL domains generated 7 themes: caregiving burden and adaptation, existential and self, family and social support, finances, information needs, physical symptoms and functioning, and psychological symptoms and wellbeing. The most investigated themes were physical and psychological symptoms, the most important for caregivers themselves were family and social support. <i>Conclusions</i>. Caregiving for brain tumour patients is shown to negatively affect QoL, particularly mental health, burden, and social life. Existing QoL research in caregivers of brain tumour patients predominantly utilises generic QoL measures designed for use in patients and draws a medicalised view of QoL priorities. The few studies using caregiver-specific QoL measures demonstrated closer alignment to caregiver preferences such as family and social support.</p>\u0000 </div>","PeriodicalId":11953,"journal":{"name":"European Journal of Cancer Care","volume":"2023 1","pages":""},"PeriodicalIF":1.8,"publicationDate":"2023-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/2023/2882837","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43129024","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Global, Regional, National Burden of Cutaneous Squamous Cell Carcinoma (1990–2019) and Predictions to 2035","authors":"Aiyuan Guo,&nbsp;Xiajing Liu,&nbsp;Heqing Li,&nbsp;Wenwei Cheng,&nbsp;Yexun Song","doi":"10.1155/2023/5484597","DOIUrl":"10.1155/2023/5484597","url":null,"abstract":"<div>\u0000 <p><i>Objective</i>. The aim of the study is to provide the burden of cutaneous squamous cell carcinoma (cSCC) in 21 regions, 204 countries, and territories from 1990 to 2019 by age, sex, and sociodemographic index (SDI) and to predict the global burden of cSCC to 2035. <i>Methods</i>. We use estimates from 2019 Global Burden of Disease (GBD) study to conduct the analysis and prediction. The burden of cSCC was estimated for 21 regions, 204 countries, and territories from 1990 to 2019, through a systematic analysis of incidence, death, and disability adjusted life years (DALYs) modelled data using the methods reported in the GBD 2019 study. We predicted the age-standardized incidence rates to 2035 at the global, regional, and national level. Results. There were 2,402,221 global incidence cases and 356,054 deaths in 2019. The age-standardized incidence rate was 30.3 and the age-standardized death rate was 0.7. cSCC, which caused 1.2 million DALYs with an ASR of 14.6 in 2019. Between 1990 and 2019, the age-standardized incidence rate increased by 36.1%, death rate increased by 6.1%, and DALY rate increased by 1.5% globally. At the regional level, the highest age-standardized incidence rate was found in high-income North America, the highest death and DALY rates were shown in Australasia. At the national level, Canada had the highest age-standardized incidence and DALY rates in 2019, and the highest death rate was shown in Tonga. A total of 11 GBD regions and 114 countries were predicted to increase in age-standardized incidence rates between 2019 and 2035, respectively. <i>Conclusions</i>. The cSCC is a major global public health challenge and the burden was often underestimated. The burden is increasing in most countries, especially in countries such as Canada, China, and regions such as Caribbean.</p>\u0000 </div>","PeriodicalId":11953,"journal":{"name":"European Journal of Cancer Care","volume":"2023 1","pages":""},"PeriodicalIF":1.8,"publicationDate":"2023-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/2023/5484597","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44913973","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Barriers and Facilitators for the Implementation of Exercise Oncology Provision in Germany: A Multilevel, Mixed-Methods Evaluation of the Network OnkoAktiv","authors":"Annelie Voland,&nbsp;Annette Lohmann,&nbsp;Lena Ansmann,&nbsp;Joachim Wiskemann","doi":"10.1155/2023/6270049","DOIUrl":"10.1155/2023/6270049","url":null,"abstract":"<div>\u0000 <p><i>Background</i>. Strong evidence supports the beneficial impact of exercise on cancer patients. However, the provision of exercise programs in Germany is highly heterogeneous. Therefore, the network OnkoAktiv (OA) enables patient consultations and referrals from coordinating regional OA centers (RE) into community-based exercise programs (CBEP). <i>Objective</i>. The aim of this study was to identify barriers and facilitators for the implementation of OA network structures from the perspective of RE and certified CBEP. <i>Methods</i>. This evaluation was executed in a sequential mixed methods design. We conducted 16 qualitative interviews with each leader in RE and the certified CBEP. Then, 89 certified CBEP were invited to a quantitative, cross-sectional survey. <i>Results</i>. We identified 11 facilitators each for RE and certified CBEP, 7 barriers for RE and 5 for certified CBEP. Barriers dealt with, for example, financing OA network structures, a lack of knowledge of exercise trainers, inadequate patient referral, and missing collaborations by healthcare professionals (HCPs). Most of the named facilitators were adequate internal organizational resources, support and reachability of OA staffs, and collaboration with HCPs. <i>Conclusion</i>. Our findings indicate different challenges for the implementation of OA network structures. Future implementation efforts should consider the evaluation of individual barriers and the development of specific solutions.</p>\u0000 </div>","PeriodicalId":11953,"journal":{"name":"European Journal of Cancer Care","volume":"2023 1","pages":""},"PeriodicalIF":1.8,"publicationDate":"2023-04-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/2023/6270049","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45237168","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Multiple Myeloma in People of Working Age: A Systematic Review and Evidence Synthesis of Experiences of Paid and Unpaid Work","authors":"Liz Forbat,&nbsp;Tim Sedgley,&nbsp;Laura Bellussi","doi":"10.1155/2023/6292479","DOIUrl":"10.1155/2023/6292479","url":null,"abstract":"<div>\u0000 <p><i>Introduction</i>. This review sought to synthesise the qualitative evidence pertaining to the experiences of myeloma patients and relatives of work, given the distinct symptom burden and illness trajectory. <i>Methods and Designs</i>. CINAHL, Medline, Web of Science, PsychINFO, SocIndex were searched on 22-Apr-2022. No limiters were used for language or date of publication. CASP was used for critical appraisal. An integrative synthesis was conducted to inductively construct analytic themes PROSPERO CRD42022323137. <i>Results</i>. 34 articles were included, published from 2004 to 2022. Nineteen were assessed as having low risk of bias, and four with moderate risk of bias. The following four themes were derived from analysis of the papers: (i) side effects, medicines, and stigma; (ii) relationships; (iii) creation and maintenance of identity; (iv) privilege and income. <i>Conclusion</i>. Myeloma impacts the engagement of patients and relatives in paid and unpaid work, yet very little is currently known on how the cancer impacts these important interdependent systems. Addressing workplace stigma, understanding the role of workplace relationships, the construction of self through work, interpreting data through a lens of life-course and, privilege offer helpful starting points.</p>\u0000 </div>","PeriodicalId":11953,"journal":{"name":"European Journal of Cancer Care","volume":"2023 1","pages":""},"PeriodicalIF":1.8,"publicationDate":"2023-04-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/2023/6292479","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44955052","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prostate Cancer, Radical Prostatectomy, Recovery, and Survivorship: A Narrative Study of How Men Make Sense of a Cancer Diagnosis","authors":"Melissa Corbally,&nbsp;Catherine McGarvey,&nbsp;Barry Kestell","doi":"10.1155/2023/1915790","DOIUrl":"10.1155/2023/1915790","url":null,"abstract":"<div>\u0000 <p>Prostate cancer invariably impacts men’s health and well-being and remains the most common male cancer. This study explored how men with prostate cancer who were scheduled for radical prostatectomy made sense of their cancer diagnosis. A narrative analysis was performed of 18 men’s life stories at three different time points: preoperatively (<i>n</i> = 13), three months postoperatively (<i>n</i> = 10), and six to nine months postoperatively (<i>n</i> = 11). In total, 34 interviews were undertaken in Ireland to examine how men talked over time. Riessman’s narrative analytic technique and structural and thematic analysis were used as the analytic framework. The following four themes emerged which reflected how men made sense of their prostate cancer diagnosis: seeking coherence, connecting through collective masculinity, rejecting a survivorship identity, and positioning prostate cancer. Seeking coherence was evident in the preoperative phase whilst the other three themes emerged in both postoperative time points. Whilst the experience of prostate cancer was an individualised one, masculine identity and narrative positioning underpinned every aspect of men’s accounts. Subscription to and expression of a masculine identity underpinned all aspects of the men’s narratives. In conclusion, it is recommended that care interventions targeted towards meeting the unmet needs of this group account for this highly masculinised experience. Appropriately sequenced information and support which is gender sensitive to individualised and collective identity expression is crucial. Acknowledgment of masculinised language is also recommended for men’s individual and collective recovery from this life-altering experience.</p>\u0000 </div>","PeriodicalId":11953,"journal":{"name":"European Journal of Cancer Care","volume":"2023 1","pages":""},"PeriodicalIF":1.8,"publicationDate":"2023-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/2023/1915790","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"64791154","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development of a Core Set of Self-Management Support Needs of Esophageal Cancer Patients: Results from a Delphi Study among Healthcare Professionals","authors":"Daniëlle J. M. Adriaans,&nbsp;Fanny B. M. Heesakkers,&nbsp;Joep A. W. Teijink,&nbsp;Angelique T. M. Dierick-van Daele,&nbsp;Jan Willem Haveman,&nbsp;Meindert N. Sosef,&nbsp;Jan Willem van den Berg,&nbsp;Marc J. van Det,&nbsp;Henk H. Hartgrink,&nbsp;Walther J. B. M. Jansen,&nbsp;Camiel Rosman,&nbsp;Sjoerd M. Lagarde,&nbsp;Stijn van Esser,&nbsp;Erwin van der Harst,&nbsp;Hanneke W. M. van Laarhoven,&nbsp;Grard A. P. Nieuwenhuijzen","doi":"10.1155/2023/3164450","DOIUrl":"10.1155/2023/3164450","url":null,"abstract":"<div>\u0000 <p><i>Objective</i>. We aimed to gain consensus on HCPs’ perspectives on self-management support information needs of patients with esophageal cancer during the preoperative phase. <i>Methods</i>. Based on the literature, observations of clinical consultations, and hospital patient information leaflets, a survey was created. HCPs were surveyed twice about their opinion on importance of information, from “not essential” to “absolutely essential,” using Delphi methods. Topics were included in the second round if predetermined criteria were met. To be included in the final list, topics had to meet criteria for consensus and stability. <i>Results</i>. 64 information items and 6 sources of support were identified. Survey response rates were 59% (68 out of 116, first round) and 75% thereafter. The final list included 33 topics, including logistical information, expectations for future health condition, complications, follow-up care, nutrition during treatment, and nutrition during recovery as topics with 100% agreement. Consensus on the source of support was reached for face-to-face contact, written information, information video, and a case manager. <i>Conclusion</i>. This study provides a list of important topics, from the perspectives of HCPs, to guide the systematic provision of education to support EC patients’ self-management during the preoperative phase. Additionally, the most preferred sources of support were face-to-face contact and a case manager.</p>\u0000 </div>","PeriodicalId":11953,"journal":{"name":"European Journal of Cancer Care","volume":"2023 1","pages":""},"PeriodicalIF":1.8,"publicationDate":"2023-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/2023/3164450","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49641136","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Noninvasive Brain Stimulation for Cancer Pain Management in Nonbrain Malignancy: A Meta-Analysis","authors":"Yung-Jiun Chien,&nbsp;Chun-Yu Chang,&nbsp;Meng-Yu Wu,&nbsp;Yung-Chen Chien,&nbsp;Hsin-Chi Wu,&nbsp;Yi-Shiung Horng","doi":"10.1155/2023/5612061","DOIUrl":"10.1155/2023/5612061","url":null,"abstract":"<div>\u0000 <p><i>Purpose</i>. Noninvasive brain stimulation (NIBS) has been reported to have analgesic effects on fibromyalgia and chronic neuropathic pain; however, its effects on cancer pain have yet to be determined. The present study aimed to evaluate the effects of NIBS on patients with pain secondary to nonbrain malignancy. <i>Methods</i>. Electronic databases including PubMed, Embase, Cochrane Library, and Web of Science were searched from inception through June 5th, 2022. Parallel, randomized, placebo-controlled studies were included that enrolled adult patients with cancer pain, except for that caused by brain tumors, compared NIBS with placebo stimulation, and reported sufficient data for performing meta-analysis. <i>Results</i>. Four parallel, randomized, sham-controlled studies were included: two of repetitive transcranial magnetic stimulation (rTMS), one of transcranial direct current stimulation (tDCS), and one of cranial electrical stimulation (CES). rTMS significantly improved pain in the subgroup analysis (standardized mean difference (SMD): −1.148, 95% confidence interval (CI): −1.660 to −0.637, (<i>p</i> &lt; 0.001)), while NIBS was not benefited in reducing pain intensity (SMD: −0.632, 95% CI: −1.356 to 0.092, <i>p</i> = 0.087). Also, NIBS significantly improved depressive symptoms (SMD: −0.665, 95% CI: −1.178 to −0.153, <i>p</i> = 0.011), especially in the form of rTMS (SMD: −0.875, 95% CI: −1.356 to −0.395, <i>p</i> &lt; 0.001) and tDCS (SMD: −1.082, 95% CI: −1.746 to −0.418, <i>p</i> = 0.001). <i>Conclusion</i>. rTMS significantly improved pain secondary to nonbrain malignancy apart from other forms of NIBS without major adverse events.</p>\u0000 </div>","PeriodicalId":11953,"journal":{"name":"European Journal of Cancer Care","volume":"2023 1","pages":""},"PeriodicalIF":1.8,"publicationDate":"2023-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/2023/5612061","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47011430","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}