European Journal of Cancer Care最新文献

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The Effects of Mindfulness-Based Stress Reduction on Overall Quality of Life and Its Components in Head and Neck Cancer: Finding Answers in a Randomized Controlled Trial 正念减压对头颈癌患者整体生活质量及其组成部分的影响:在一项随机对照试验中找到答案
IF 1.9 4区 医学
European Journal of Cancer Care Pub Date : 2026-01-22 DOI: 10.1155/ecc/2835450
Zheng Zhang, Qingqin Zhang, Ping Lu, Hao Cheng, Haolong Zhang, Sen Wu, Xiaomei Liu, Yuanyuan Hu, Mohammad Farris Iman Leong Bin Abdullah
{"title":"The Effects of Mindfulness-Based Stress Reduction on Overall Quality of Life and Its Components in Head and Neck Cancer: Finding Answers in a Randomized Controlled Trial","authors":"Zheng Zhang,&nbsp;Qingqin Zhang,&nbsp;Ping Lu,&nbsp;Hao Cheng,&nbsp;Haolong Zhang,&nbsp;Sen Wu,&nbsp;Xiaomei Liu,&nbsp;Yuanyuan Hu,&nbsp;Mohammad Farris Iman Leong Bin Abdullah","doi":"10.1155/ecc/2835450","DOIUrl":"https://doi.org/10.1155/ecc/2835450","url":null,"abstract":"<div>\u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>This multicenter randomized controlled trial compared the changes in the degree of quality of life (QOL) and its components between mindfulness-based stress reduction (MBSR) and treatment-as-usual (TAU) groups over 3 points of time (T<sub>0</sub> = preintervention baseline assessment; T<sub>1</sub> = postintervention, which was right after the intervention completed or 6 weeks after the intervention began; and T<sub>2</sub> = follow-up, which was 12 weeks after the intervention ended) in head and neck cancer (HNC) survivors.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>A total of 120 HNC patients were randomized into MBSR (<i>n</i> = 60) and TAU (<i>n</i> = 60) groups and administered the demographic and clinical data questionnaire and the Malay version of the Functional Assessment for Cancer Therapy-General and Head and Neck module (FACT-General and FACT-HN; to assess the QOL) across the three time points (T<sub>0,</sub> T<sub>1,</sub> and T<sub>2</sub>).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>In the MBSR group, the main effect of the interaction between group and time for total FACT-General [F(2, 232) = 24.7, <i>p</i> &lt; 0.001], social relationship [F(2, 227) = 21.7, <i>p</i> &lt; 0.001], and emotion-related QOL [F(2, 230) = 35.1, <i>p</i> &lt; 0.001] was significant after adjusting for confounding factors (such as age of participants, marital status, types of HNC, and stage of cancer). The total FACT-General and social relationship-related QOL scores of participants significantly increased from T<sub>0</sub> to T<sub>1</sub> and from T<sub>1</sub> to T<sub>2</sub>, while the emotion-related QOL score significantly increased from T<sub>1</sub> to T<sub>2</sub>. However, MBSR exhibited only a small effect on the physical health, functional, and the HN-related QOL scores in the MBSR group across the three time points.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>MBSR enhances the overall QOL by enhancing the social and emotional components of QOL across time when compared with TAU. Hence, MBSR may be considered as part of the treatment regime for HNC, but its effect on QOL among HNC patients should be confirmed in the future study with longer follow-up assessments.</p>\u0000 \u0000 <p><b>Trial Registration:</b>ClinicalTrials.gov identifier: NCT04800419</p>\u0000 </section>\u0000 </div>","PeriodicalId":11953,"journal":{"name":"European Journal of Cancer Care","volume":"2026 1","pages":""},"PeriodicalIF":1.9,"publicationDate":"2026-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/ecc/2835450","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146091526","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Quality of Life and Needs of Patients Undergoing CAR-T Cell Therapy: The Patients’ Perspective CAR-T细胞治疗患者的生活质量和需求:患者的观点
IF 1.9 4区 医学
European Journal of Cancer Care Pub Date : 2026-01-18 DOI: 10.1155/ecc/6766876
S. Alfieri, E. Criscuolo, A. Chiappella, M. Bosisio, R. Petrigliano, L. Gangeri, B. Scacciati, N. Pozzetto, M. Cani, C. Borreani
{"title":"Quality of Life and Needs of Patients Undergoing CAR-T Cell Therapy: The Patients’ Perspective","authors":"S. Alfieri,&nbsp;E. Criscuolo,&nbsp;A. Chiappella,&nbsp;M. Bosisio,&nbsp;R. Petrigliano,&nbsp;L. Gangeri,&nbsp;B. Scacciati,&nbsp;N. Pozzetto,&nbsp;M. Cani,&nbsp;C. Borreani","doi":"10.1155/ecc/6766876","DOIUrl":"https://doi.org/10.1155/ecc/6766876","url":null,"abstract":"&lt;div&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Background&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;Despite the strong emphasis in recent scientific literature on the pharmacological features of CAR-T cells, patients’ quality of life (QoL) and needs, by contrast, have received little attention.&lt;/p&gt;\u0000 &lt;/section&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Aim&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;This study aims to investigate patients’ perspectives on their QoL and needs in a referral centre for CAR-T cell treatment in Italy.&lt;/p&gt;\u0000 &lt;/section&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Methods&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;This is a descriptive, qualitative and prospective study conducted at a single centre. Patients were recruited from a list of those who underwent the treatment or who were eligible to do so. Patients were asked to participate in a semistructured interview. The number of people to be interviewed was not predetermined but was established continuously until meaning saturation was achieved. The interviews were audio recorded, transcribed verbatim, and analysed through constructivist lenses using reflexive thematic analysis.&lt;/p&gt;\u0000 &lt;/section&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Results&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;Participants were 12 patients (age mean: 57.88; SD = 9.62; range = 39–70) enrolled in an Italian Comprehensive Cancer Center. From the analysis of the interviews, 7 themes were identified: (1) therapeutic journey to reach CAR-T cell therapy; (2) CAR-T cell images; (3) perception of the quality of care received; (4) three challenging moments; (5) emerging issues to address; (6) coping strategies and (7) needs. Some themes have been organised into subthemes that detail their specific aspects. Starting from the quotations, 41 needs have been identified and organised into 5 macro areas: (1) needs during hospitalisation; (2) existential needs; (3) needs for improving QoL; (4) need for quality and quantity of information and (5) needs for care. The list of needs has been transformed into a checklist, serving as a preliminary step for subsequent studies aimed at identifying and quantifying the needs of patients.&lt;/p&gt;\u0000 &lt;/section&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Conclusions&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;Results indicate that the QoL of patients undergoing CAR-T cell therapy is impaired during hospitalisation and in the subsequent months following infusion. Physical symptoms including fatigue, drowsiness, cognitive slowing or dysfunction emerged. Nonetheless, patients employ various coping strategies to cope with these challenging periods. A multitude of needs, often unaddressed, has emerged. For this matter, a first draft for a checklist of needs has been realised. Should future studies validate its s","PeriodicalId":11953,"journal":{"name":"European Journal of Cancer Care","volume":"2026 1","pages":""},"PeriodicalIF":1.9,"publicationDate":"2026-01-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/ecc/6766876","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146002464","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Palliative Care Stigma in Oncology: An Integrated Systematic Literature Review 姑息治疗耻辱在肿瘤学:一个综合系统的文献综述
IF 1.9 4区 医学
European Journal of Cancer Care Pub Date : 2026-01-17 DOI: 10.1155/ecc/6222421
R. Alexander, P. Meek, C. Stephens
{"title":"Palliative Care Stigma in Oncology: An Integrated Systematic Literature Review","authors":"R. Alexander,&nbsp;P. Meek,&nbsp;C. Stephens","doi":"10.1155/ecc/6222421","DOIUrl":"https://doi.org/10.1155/ecc/6222421","url":null,"abstract":"<div>\u0000 \u0000 <section>\u0000 \u0000 <h3> Purpose</h3>\u0000 \u0000 <p>To conduct an integrated systematic literature review to explore (1) the presence and impact of stigma surrounding palliative care (PC) in Oncology particularly related to the care of adults with advanced cancer and (2) how Oncology healthcare providers (OHCPs) may contribute and perpetuate PC stigma, a factor associated with the underutilization of PC.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>A comprehensive search was conducted in four major databases using PRISMA guidelines. Thirty-two articles met the inclusion criteria focused on the perspectives of PC by OHCPs who treat adults with advanced cancer. Guided by Goffman’s Theory of Stigma, articles were iteratively reviewed and stigma-related themes were generated.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Six major themes emerged defining the concept of Oncology PC stigma and were categorized into two groups, which Goffman labels as “stigmatized” and “stigmatizers.” Assumptions, fear, and discomfort are the three common perceptions OHCPs which drive their behaviors as the stigmatizers. Avoidance, undesired differentness, and negative association with the term “palliative care” are the three reoccurring behaviors and perceptions seen in adults with advanced-stage cancer, who are the stigmatized. A novel conceptual framework is presented with these six major characteristics of Oncology PC stigma with their corresponding outcomes.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Societal stigma associated with PC in Oncology is pervasive and driven by behaviors and perceptions of not only patients and their families who are reluctant to use PC but OHCPs themselves. Findings underscore the need for interventions that address OHCP’s lack of understanding about how their own perceptions and behaviors may impact patient PC utilization and outcomes.</p>\u0000 </section>\u0000 </div>","PeriodicalId":11953,"journal":{"name":"European Journal of Cancer Care","volume":"2026 1","pages":""},"PeriodicalIF":1.9,"publicationDate":"2026-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/ecc/6222421","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146007725","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Construction of a Platelet-Related Gene Signature for Predicting Prognosis and Drug Sensitivity in Colorectal Cancer 预测结直肠癌预后和药物敏感性的血小板相关基因标记的构建
IF 1.9 4区 医学
European Journal of Cancer Care Pub Date : 2026-01-13 DOI: 10.1155/ecc/6430579
Yufang Wang, Junjie Yang, Xiaofang Xu, Tao Yu
{"title":"Construction of a Platelet-Related Gene Signature for Predicting Prognosis and Drug Sensitivity in Colorectal Cancer","authors":"Yufang Wang,&nbsp;Junjie Yang,&nbsp;Xiaofang Xu,&nbsp;Tao Yu","doi":"10.1155/ecc/6430579","DOIUrl":"https://doi.org/10.1155/ecc/6430579","url":null,"abstract":"<div>\u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Colorectal cancer (CRC) ranks among the most prevalent forms of cancer and is a significant contributor to cancer-related mortality globally. Platelets play a crucial role in tumor biology by interacting with various immune cells, influencing multiple biological processes.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>We utilized datasets from TCGA, GSE17536, GSE39582, and GSE103479 to develop a platelet-related gene signature (PRS) using least absolute shrinkage and selection operator (LASSO) analysis. The effectiveness of PRS in predicting responses to immunotherapy was assessed using three immunotherapy datasets (GSE91061, GSE78220, and IMvigor210) and several predictive scores.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The PRS demonstrated robust performance in forecasting the survival outcomes of CRC patients. In the TCGA cohort, the areas under the ROC curves for 1-, 3-, and 5-year survival were 0.845, 0.849, and 0.785, respectively. Further analysis identified PRS as an independent risk factor for CRC patients. A nomogram was constructed to predict clinical outcomes for CRC patients. Additionally, a lower PRS score was associated with higher TMB scores, elevated PD1 and CTLA4 immunopheno scores, reduced TIDE and immune escape scores, higher response rates, and more favorable clinical outcomes, suggesting better immunotherapy responses. Conversely, lower PRS scores correlated with increased IC<sub>50</sub> values for certain drugs used in chemotherapy and targeted therapy. Patients in the high-risk group exhibited elevated gene set scores related to cancer hallmarks such as Notch signaling, hypoxia, and glycolysis.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Our study established a PRS for CRC that serves as a valuable tool for predicting prognosis, stratifying risk, and guiding treatment decisions for CRC patients.</p>\u0000 </section>\u0000 </div>","PeriodicalId":11953,"journal":{"name":"European Journal of Cancer Care","volume":"2026 1","pages":""},"PeriodicalIF":1.9,"publicationDate":"2026-01-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/ecc/6430579","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146002229","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Competing Risk of Specific Mortality in Prostate Cancer Patients in Brazil: A Retrospective Cohort Study 巴西前列腺癌患者特定死亡率的竞争风险:一项回顾性队列研究
IF 1.9 4区 医学
European Journal of Cancer Care Pub Date : 2026-01-13 DOI: 10.1155/ecc/9297248
Wesley Rocha Grippa, Luís Carlos Lopes-Júnior
{"title":"Competing Risk of Specific Mortality in Prostate Cancer Patients in Brazil: A Retrospective Cohort Study","authors":"Wesley Rocha Grippa,&nbsp;Luís Carlos Lopes-Júnior","doi":"10.1155/ecc/9297248","DOIUrl":"https://doi.org/10.1155/ecc/9297248","url":null,"abstract":"<div>\u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Prostate cancer is among the most common malignancies worldwide and a leading cause of premature mortality in men. Although survival rates have improved globally, disparities persist. Here, we aim to analyze the risk factors associated with prostate cancer-specific mortality among patients in a southeastern Brazilian state.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>We conducted a retrospective cohort study using data from 10,556 patients diagnosed with prostate cancer between 2000 and 2016. Data were extracted from hospital-based cancer registries linked to the state Mortality Information System. Patients were followed up for a minimum of 5 years and classified as alive, deceased from prostate cancer, or deceased from other causes. Subdistribution hazard ratios (SHRs) were estimated using Fine–Gray competing-risks models.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>By the end of 2021, 6388 patients were alive, 1936 had died from prostate cancer, and 2232 had died from other causes. Older age increased prostate cancer-specific mortality (SHR per 10 year increment = 1.098; 95% CI: 1.024–1.176), while distant metastasis was the strongest clinical predictor (SHR = 5.315; 95% CI: 4.676–6.041). Higher educational attainment remained statistically associated with lower prostate cancer-specific mortality in the multivariable competing-risks model (SHR = 0.767; 95% CI: 0.629–0.935), although the protective effect was attenuated after adjustment. Surgery (SHR = 0.382; 95% CI: 0.309–0.471) and radiotherapy (SHR = 0.477; 95% CI: 0.396–0.575) were also associated with lower cancer-specific mortality, while hormone therapy remained associated with higher mortality, reflecting treatment selection among patients with a more advanced disease rather than a causal treatment effect.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Age, education, metastatic disease, and treatment modalities were significantly associated with prostate cancer-specific mortality. These findings reinforce the importance for equitable access to early diagnosis pathways and curative treatment options and highlight the value of competing-risks methods for accurately estimating prostate cancer outcomes in population-based settings.</p>\u0000 </section>\u0000 </div>","PeriodicalId":11953,"journal":{"name":"European Journal of Cancer Care","volume":"2026 1","pages":""},"PeriodicalIF":1.9,"publicationDate":"2026-01-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/ecc/9297248","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146002030","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Being a Resource or a Burden, Preparing Return to Work During Treatment: Breast Cancer Survivors’ Experiences 成为资源还是负担,在治疗期间准备重返工作岗位:乳腺癌幸存者的经历
IF 1.9 4区 医学
European Journal of Cancer Care Pub Date : 2026-01-09 DOI: 10.1155/ecc/7050251
Siv Tove Aunan, May A. Hauken, Kristin G. Bodsberg, Britt S. Hansen
{"title":"Being a Resource or a Burden, Preparing Return to Work During Treatment: Breast Cancer Survivors’ Experiences","authors":"Siv Tove Aunan,&nbsp;May A. Hauken,&nbsp;Kristin G. Bodsberg,&nbsp;Britt S. Hansen","doi":"10.1155/ecc/7050251","DOIUrl":"https://doi.org/10.1155/ecc/7050251","url":null,"abstract":"<div>\u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>The return to work (RTW) is critical for physical, psychosocial, and financial wellbeing and the normalization of breast cancer (BC) survivors. While research indicates that these survivors experience several barriers to the RTW after treatment, limited knowledge exists on preparing the RTW during treatment from women’s perspectives.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>To explore the experiences of women with BC preparing their RTW during cancer treatment.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>A qualitative, inductive study was performed and 21 BC survivors with experience from RTW were interviewed individually. Qualitative content analysis was used to analyze the interviews.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Most participants believed that their RTW would be unproblematic. They used all their energy to remain hopeful. Losing value as a human being and as an employee was a painful experience. The need for support to keep hope alive and nurture their feelings of value was described as crucial.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Feelings of hope and value were sustained through positive contact with the workplace, receipt of realistic information on the RTW, continuity of treatment and care, experiencing active listening from healthcare providers, and receipt of information about and coordination of support services.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Implications for practice</h3>\u0000 \u0000 <p>HCPs should inform BC survivors that their disease may have long-term side effects and is a burden that may affect their work life and cause cognitive and psychological distress.</p>\u0000 \u0000 <p>HCPs must strive to provide continuity and individualized information during treatment regarding optimal use of the sick leave system, legal rights, support service, contact with work, and individualized RTW planning.</p>\u0000 </section>\u0000 </div>","PeriodicalId":11953,"journal":{"name":"European Journal of Cancer Care","volume":"2026 1","pages":""},"PeriodicalIF":1.9,"publicationDate":"2026-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/ecc/7050251","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145941566","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prognostic Significance of Pre- and Posttreatment 18F-FDG PET/CT-Derived SUV-max in Esophageal Cancer: A South Asian Perspective 食管癌治疗前后18F-FDG PET/ ct衍生SUV-max的预后意义:南亚视角
IF 1.9 4区 医学
European Journal of Cancer Care Pub Date : 2026-01-08 DOI: 10.1155/ecc/9653240
Sajida Qureshi, Waqas Ahmad Abbasi, Mehreen Ansari, Raheel Ahmed, Mubashir Iqbal, Hanieya Saiyed, Hira Abdul Jalil, Saba Mughal, Muhammad Saeed Quraishy
{"title":"Prognostic Significance of Pre- and Posttreatment 18F-FDG PET/CT-Derived SUV-max in Esophageal Cancer: A South Asian Perspective","authors":"Sajida Qureshi,&nbsp;Waqas Ahmad Abbasi,&nbsp;Mehreen Ansari,&nbsp;Raheel Ahmed,&nbsp;Mubashir Iqbal,&nbsp;Hanieya Saiyed,&nbsp;Hira Abdul Jalil,&nbsp;Saba Mughal,&nbsp;Muhammad Saeed Quraishy","doi":"10.1155/ecc/9653240","DOIUrl":"https://doi.org/10.1155/ecc/9653240","url":null,"abstract":"<div>\u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Esophageal cancer (EC) is a leading cause of cancer-related deaths globally, with South Asia bearing a particularly high disease burden. While <sup>18</sup>F-FDG PET/CT-derived SUV-max values are explored for their prognostic relevance, previous findings remain inconsistent, and data from South Asian populations are limited.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>This retrospective study analyzed data from 42 biopsy-confirmed EC patients treated between June 2019 and December 2024 at a tertiary care center. All included patients had initially received standardized neoadjuvant chemoradiotherapy and underwent both pre- and posttreatment 18F-FDG PET/CT imaging. Associations between clinicopathological factors and survival status were evaluated using the independent <i>t</i>-test, Chi-square test, and Fisher’s exact test. Receiver operating characteristic (ROC) analysis was performed to determine optimal SUV-max cutoffs. Survival outcomes were assessed using Kaplan–Meier estimates, log-rank test, and Cox proportional hazards regression to identify independent predictors of mortality.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Kaplan–Meier analysis showed significantly reduced survival in patients with elevated nodal SUV-max values both pre- and posttreatment. In multivariate Cox regression, posttreatment nodal SUV-max was the strongest independent predictor of mortality (HR = 52.9, <i>p</i> = 0.012), followed by pretreatment nodal SUV-max (HR = 15.3, <i>p</i> = 0.034), while tumor SUV-max values (pre- and posttreatment) did not demonstrate independent prognostic significance.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Nodal SUV-max on PET/CT is a strong, independent predictor of survival in EC and may effectively guide personalized treatment decisions.</p>\u0000 </section>\u0000 </div>","PeriodicalId":11953,"journal":{"name":"European Journal of Cancer Care","volume":"2026 1","pages":""},"PeriodicalIF":1.9,"publicationDate":"2026-01-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/ecc/9653240","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145941700","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Joinpoint Analysis and Age–Period–Cohort Effect on Mortality of Colorectal Cancer in Iran From 1990 to 2021 1990 - 2021年伊朗结直肠癌死亡率的结合点分析和年龄-时期-队列效应
IF 1.9 4区 医学
European Journal of Cancer Care Pub Date : 2026-01-08 DOI: 10.1155/ecc/1617252
Fatemeh Jafari, Soheila Khodakarim, Abbas Rezaianzadeh, Hamed Karami
{"title":"Joinpoint Analysis and Age–Period–Cohort Effect on Mortality of Colorectal Cancer in Iran From 1990 to 2021","authors":"Fatemeh Jafari,&nbsp;Soheila Khodakarim,&nbsp;Abbas Rezaianzadeh,&nbsp;Hamed Karami","doi":"10.1155/ecc/1617252","DOIUrl":"https://doi.org/10.1155/ecc/1617252","url":null,"abstract":"<div>\u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Colorectal cancer reported the fourth most common cancer in Iran. The aim of this study was to describe the time trends of colorectal cancer mortality from 1990 to 2021, focusing on the effects of age, period, and cohort.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Method</h3>\u0000 \u0000 <p>Our data included the number of colorectal cancer deaths and population recorded by the global burden of disease (GBD) and categorized by 5-year age groups from 1990 to 2021. Joinpoint regression and the age–period–cohort (APC) model were used to reflect temporal trend and effects of age, period, and cohort on colorectal cancer mortality, respectively.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The crude mortality rate of colorectal cancer was significantly increased in men, with an average annual percentage change (AAPC) of 1.558% (95% confidence interval [CI]: 1.398%, 1.778%), while the crude mortality rate increased (AAPC = 1.340%; 95% CI: 1.215%, 1.465%) and the age-standardized mortality rate decreased in women (AAPC = −0.307%; 95% CI: −0.460%, −0.152%). APC analysis showed that the risk of death increased with age in both genders (Coef<sub>15–19</sub> = −2.823 vs. Coef<sub>&gt; 95</sub> = 1.731 in men and Coef<sub>15–19</sub> = −2.628 vs. Coef<sub>&gt; 95</sub> = 1.964 in women) and time (Coef<sub>1992–1996</sub> = −0.385 vs. Coef<sub>2017–2021</sub> = 0.438 in men and Coef<sub>1992–1996</sub> = −0.271 vs. Coef<sub>2017–2021</sub> = 0.380 in women) and was lower in later-born cohort (Coef<sub>2002–2006</sub> = −1.590 in men and Coef<sub>2002–2006</sub> = −1.543 in women) than earlier-born cohort (Coef<sub>&lt; 1901</sub> = 1.458 in men and Coef<sub>&lt; 1901</sub> = 1.208 in women).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Due to the increasing trend from colorectal cancer mortality and age and period effects, it seems necessary to modify early detection strategies and increase public awareness to reduce the burden of this cancer.</p>\u0000 </section>\u0000 </div>","PeriodicalId":11953,"journal":{"name":"European Journal of Cancer Care","volume":"2026 1","pages":""},"PeriodicalIF":1.9,"publicationDate":"2026-01-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/ecc/1617252","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145941626","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Listen to Lung Cancer Patients’ Emotions With Photographs Taken by Them: A Mixed-Method Study 用照片倾听肺癌患者的情绪:一项混合方法研究
IF 1.9 4区 医学
European Journal of Cancer Care Pub Date : 2025-12-31 DOI: 10.1155/ecc/1098567
Aysun Akcakaya Can, Sevilay Hintistan, Yilmaz Bulbul
{"title":"Listen to Lung Cancer Patients’ Emotions With Photographs Taken by Them: A Mixed-Method Study","authors":"Aysun Akcakaya Can,&nbsp;Sevilay Hintistan,&nbsp;Yilmaz Bulbul","doi":"10.1155/ecc/1098567","DOIUrl":"https://doi.org/10.1155/ecc/1098567","url":null,"abstract":"<div>\u0000 \u0000 <section>\u0000 \u0000 <h3> Aim</h3>\u0000 \u0000 <p>This study was conducted to examine the emotional experiences of lung cancer patients.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>This study, carried out with an intervention design, is a mixed-method study in two parts. The qualitative part of the mixed method was enriched with photovoice methodology. The study used a criterion sampling technique, and 17 participants were interviewed. Some scales collected quantitative data from the survey, and qualitative data were collected through “semistructured interviews” and “photographs.”</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The themes in the first part are “meeting with cancer and a new life.” The second part determines the “range of emotions, the world through my window, and perspective.” The study revealed in striking detail that lung cancer patients experience many different emotions simultaneously. There was no significant difference in the scale mean scores of the participants.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Phototherapy is essential for revealing lung cancer patients’ emotions and concentrating on positive emotions. Cancer nurses can also add phototherapy as a simple, feasible, and accessible method of caring for lung cancer patients. Thus, lung cancer patients can participate in life through the photographs they take.</p>\u0000 </section>\u0000 </div>","PeriodicalId":11953,"journal":{"name":"European Journal of Cancer Care","volume":"2025 1","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/ecc/1098567","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145905239","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Current Situation and Influencing Factors of Vascular Access Decision-Making Conflicts Among Breast Cancer Chemotherapy Patients in China: A Multicenter Investigation Based on the Ottawa Decision Framework 中国乳腺癌化疗患者血管通路决策冲突现状及影响因素:基于渥太华决策框架的多中心调查
IF 1.9 4区 医学
European Journal of Cancer Care Pub Date : 2025-12-30 DOI: 10.1155/ecc/9931282
Jialu Sun, Pengli Chen, Shouxun He, Mengzhu Jiang, Jinhong Lü, Lina Wang, Hongru Wang
{"title":"Current Situation and Influencing Factors of Vascular Access Decision-Making Conflicts Among Breast Cancer Chemotherapy Patients in China: A Multicenter Investigation Based on the Ottawa Decision Framework","authors":"Jialu Sun,&nbsp;Pengli Chen,&nbsp;Shouxun He,&nbsp;Mengzhu Jiang,&nbsp;Jinhong Lü,&nbsp;Lina Wang,&nbsp;Hongru Wang","doi":"10.1155/ecc/9931282","DOIUrl":"https://doi.org/10.1155/ecc/9931282","url":null,"abstract":"<div>\u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>To explore the decision-making conflicts regarding vascular access devices in Chinese breast cancer patients undergoing chemotherapy and the influencing factors.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Design</h3>\u0000 \u0000 <p>A multicenter cross-sectional survey study.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Method</h3>\u0000 \u0000 <p>A total of 308 breast cancer patients undergoing chemotherapy were included. Questionnaires were conducted using a general information questionnaire, the Chinese version of the Decision Conflict Scale, the Decision Participation Expectation Scale, and the Decision Preparation Scale. Multivariate linear regression analysis was used to investigate the influencing factors of decision conflict regarding vascular access devices in breast cancer patients undergoing chemotherapy.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Result</h3>\u0000 \u0000 <p>The level of decision conflict in the patients was relatively high, with a score of 40.88 ± 9.64, significantly higher than the critical value of 37.5. During the decision-making process of the patients, 162 cases (52.6%) tended to share the decision with the doctor, but in the actual participation process, 105 cases (34.9%) made the decision passively. There were a negative correlation between patient decision conflict and decision preparation and a positive correlation between patient decision conflict and decision participation. Age, unmarried status, average monthly family income, understanding of the disease, understanding of vascular access, and decision preparation were the main influencing factors of decision conflict.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>There is a discrepancy between the expected decision-making for vascular access devices among Chinese breast cancer chemotherapy patients and the actual participation. The level of decision conflicts is relatively high, and it is influenced by multiple factors. Medical staff should enhance communication with patients, respect their decision preferences, develop decision support tools, provide appropriate decision support to patients, reduce decision conflicts, and minimize decision regret.</p>\u0000 </section>\u0000 </div>","PeriodicalId":11953,"journal":{"name":"European Journal of Cancer Care","volume":"2025 1","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/ecc/9931282","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145905174","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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