European Archives of Oto-Rhino-Laryngology最新文献_第5页

A novel method of finding accessory nerve during head and neck surgery. 头颈部手术中寻找副神经的新方法。

IF 2.2 3区医学

European Archives of Oto-Rhino-Laryngology Pub Date : 2025-08-01 Epub Date: 2025-05-14 DOI: 10.1007/s00405-025-09393-x

G Ozyigit, H B Cobanoğlu, S Arslan, A F Ozyasar, O Bahadır, A U Isik

{"title":"A novel method of finding accessory nerve during head and neck surgery.","authors":"G Ozyigit, H B Cobanoğlu, S Arslan, A F Ozyasar, O Bahadır, A U Isik","doi":"10.1007/s00405-025-09393-x","DOIUrl":"10.1007/s00405-025-09393-x","url":null,"abstract":"Introduction and purpose: In this prospective study, we performed neck morphological measurements and the relationship between the nerve and important anatomical structures in the neck to prevent spinal accessory nerve (SAN) damage in patients who underwent neck dissection.Methods: This study was conducted prospectively between October 2021 and September 2023 in 80 patients who underwent neck dissection due to head and neck malignancy.Results: The mean age of 59.2 ± 17.07 years (18-90 years) of the 80 patients, 54 were men and 26 were women. There was a positive correlation between the distance between the NAM-SAN and the sternocleidomastoid (Scm) muscle thickness(r = 0.242, p = 0.03). There was a positive correlation between the distance between the NAM-SAN and the distance between the mastoid apex and the clavicle midline (r = 0.235, p = 0.036). There was a statistically significant negative correlation between the distance between the NAM-SAN and age (r = - 0.324 p = 0.003). There was a positive correlation between the trapezius-SAN and the distance between the mandibula angulus-clavicle midline (r = -0.243 p = 0.03).Conclusion: The spinal accessory nerve must be sought for higher than the estimated point In patients which with more scm thickness. It should be considered that as the preoperatively measured mastoid apex-clavicle distance increases, the distance between the NAM and the SAN increases. It should be taken into consideration that the course of the SAN in the posterior triangle will be longer in patients with longer necks. It should be noted that as age increases, the distance between the SAN and NAM decreases.","PeriodicalId":11952,"journal":{"name":"European Archives of Oto-Rhino-Laryngology","volume":" ","pages":"4251-4258"},"PeriodicalIF":2.2,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12399439/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143959716","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Long-term clinical and audiometric outcomes after the implantation of piezoelectric bone conduction devices in children: a prospective cohort study. 儿童植入压电骨传导装置后的长期临床和听力学结果：一项前瞻性队列研究。

IF 2.2 3区医学

European Archives of Oto-Rhino-Laryngology Pub Date : 2025-08-01 Epub Date: 2025-03-26 DOI: 10.1007/s00405-025-09339-3

Faisal Zawawi, Afnan F Bukhari, Sara A Khairy, Mohamed Garrada

{"title":"Long-term clinical and audiometric outcomes after the implantation of piezoelectric bone conduction devices in children: a prospective cohort study.","authors":"Faisal Zawawi, Afnan F Bukhari, Sara A Khairy, Mohamed Garrada","doi":"10.1007/s00405-025-09339-3","DOIUrl":"10.1007/s00405-025-09339-3","url":null,"abstract":"Background: Bone conduction devices are hearing assistive devices that are used in many children who have conductive hearing loss, mixed hearing loss or single sided deafness. The aim of this study is to assess long-term outcomes of children who underwent piezoelectric bone conductive device implantation.Method: A prospective cohort of children who underwent Osia system implantation (OSI200) between the period of Jan 2021 and December 2022. The main Outcome measures were; Long-term complications, hearing thresholds, speech discrimination, sound localization and quality of life.Results: 25 children were implanted with 27 devices. The median surgical time 39 min. 6 children had single sided deafness, 21 ears had conductive hearing loss due to microtia/canal atresia (20 ears) or chronic ear disease (1 ear). None of the patients had any major adverse events. In children with conductive hearing loss, the median threshold of improvement was 37.5 dB. All patients reported significant improvement of their auditory function. Aided thresholds were best at 1 kHz (median 20 dB HL). Recorded gains were measured up 8000 Hz reflecting good auditory performance even at high frequencies. Speech Discrimination when using the Osia was 89% and self-reported hearing and quality of life by participants improved in all domains assessed.Conclusion: Osia system is a safe and effective solution to restore hearing without any major long term complications. It provides auditory benefits that covers a wide range of frequencies. Children had significant improvement in their ability to sound localize as well as QoL. Osia surgery can be performed in a routine day surgery setting safely in children.","PeriodicalId":11952,"journal":{"name":"European Archives of Oto-Rhino-Laryngology","volume":" ","pages":"4049-4056"},"PeriodicalIF":2.2,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143718327","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Dysphagia from an aberrant internal carotid artery: a case report. 颈内动脉异常引起的吞咽困难1例。

IF 2.2 3区医学

European Archives of Oto-Rhino-Laryngology Pub Date : 2025-08-01 Epub Date: 2025-05-07 DOI: 10.1007/s00405-025-09417-6

Marie Bjerg Larsen, Pádraig O'Leary

引用次数: 0

Free-flap surgery with double innervation for smiling restoration in long standing facial paralysis: a literature review. 双神经支配自由瓣手术治疗久治性面瘫微笑修复的文献回顾。

IF 2.2 3区医学

European Archives of Oto-Rhino-Laryngology Pub Date : 2025-08-01 Epub Date: 2025-03-07 DOI: 10.1007/s00405-025-09287-y

Rita De Berardinis, Veronica Santoro, Marta Tagliabue, Fabiana Allevi, Francesco Chu, Stefano Riccio, William Russell-Edu, Mohssen Ansarin, Federico Biglioli

{"title":"Free-flap surgery with double innervation for smiling restoration in long standing facial paralysis: a literature review.","authors":"Rita De Berardinis, Veronica Santoro, Marta Tagliabue, Fabiana Allevi, Francesco Chu, Stefano Riccio, William Russell-Edu, Mohssen Ansarin, Federico Biglioli","doi":"10.1007/s00405-025-09287-y","DOIUrl":"10.1007/s00405-025-09287-y","url":null,"abstract":"Purpose: Currently, free-flap surgery with double innervation is considered a reliable and effective treatment in case of long standing facial paralysis. This study aimed to provide a current review of the literature (the \"current state of the art\") on lower third of the facial reanimation in restoring the voluntary and spontaneous smile in adult population using dual innervation free flap surgery.Methods: We conducted a comprehensive literature review of all relevant papers by searching the electronic databases MEDLINE, Embase, Scopus, and the Cochrane Library.Results: We included 12 retrospective studies involving 147 patients, five of which used the latissimus dorsi double innervation technique (42 patients) and seven of which investigated double innervation with a gracilis free flap (105 patients). In this review, we summarised the available data on smile recovery after free flap double innervation surgery. In half of the included studies, smiling was completely recovered.Conclusions: Our study confirms that free flap surgery with dual innervation for long-term paralysis of the lower third of the face can guarantee comparable results using latissimus dorsi or gracilis free flaps. The best option depends on the case, taking into account the surgeon's skills and experience, as well as the patient's wishes and expectations.","PeriodicalId":11952,"journal":{"name":"European Archives of Oto-Rhino-Laryngology","volume":" ","pages":"3855-3867"},"PeriodicalIF":2.2,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143572627","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Post-operative prognostication of patients diagnosed with Hurthle cell carcinoma: a machine learning approach. Hurthle细胞癌患者的术后预后：一种机器学习方法。

IF 2.2 3区医学

European Archives of Oto-Rhino-Laryngology Pub Date : 2025-08-01 Epub Date: 2025-03-14 DOI: 10.1007/s00405-025-09299-8

Arnavaz Hajizadeh Barfejani, Mohammad Reza Balali, Nabgouri Younes, Mohammad Taha Kabiri Tameh, Shiva Borzooei, Ghodratollah Roshanaei, Aidin Tarokhian

{"title":"Post-operative prognostication of patients diagnosed with Hurthle cell carcinoma: a machine learning approach.","authors":"Arnavaz Hajizadeh Barfejani, Mohammad Reza Balali, Nabgouri Younes, Mohammad Taha Kabiri Tameh, Shiva Borzooei, Ghodratollah Roshanaei, Aidin Tarokhian","doi":"10.1007/s00405-025-09299-8","DOIUrl":"10.1007/s00405-025-09299-8","url":null,"abstract":"Objectives: To evaluate the performance of machine learning models in predicting the 5-year overall survival of patients with Hurthle cell carcinoma, and to identify significant prognostic factors influencing survival.Methods: A retrospective cohort study was conducted using data from the Surveillance, Epidemiology, and End Results database, encompassing patients treated between 2010 and 2015. Key variables included demographic information (age, sex, race), clinical characteristics (tumor size, T, N, M stages, and overall stage), and survival outcomes. Patients were included if they had complete data, were not censored before 60 months of follow-up, and had undergone thyroid surgery.Results: The study included 1,143 patients with a mean age of 57.7 years (standard deviation = 15.8). The cohort consisted of 770 females (67.4%) and was predominantly White (83.0%). Tumor classifications were varied, with T2 being most common (37.2%). The majority had no nodal involvement (94.1%) or distant metastasis (97.6%). The support vector model achieved the highest area under receiver characteristics operating curve of 0.8402 (95% CI: 0.7915 to 0.8847), indicating good predictive performance. Sensitivity and specificity were 81.16% and 73.72%, respectively. The Brier score for the model was 0.1223, demonstrating adequate calibration. Higher age and T classification were the most significant predictors of decreased survival, while being female was associated with increased survival.Conclusion: Machine learning models, particularly the support vector model, effectively predicted 5-year overall survival in patients with Hurthle cell carcinoma. The study highlights age and tumor extent as critical prognostic factors.","PeriodicalId":11952,"journal":{"name":"European Archives of Oto-Rhino-Laryngology","volume":" ","pages":"4217-4225"},"PeriodicalIF":2.2,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143633752","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Are chatbots a reliable source for patient frequently asked questions on neck masses? 聊天机器人是患者关于颈部肿块的常见问题的可靠来源吗？

IF 2.2 3区医学

European Archives of Oto-Rhino-Laryngology Pub Date : 2025-08-01 Epub Date: 2025-04-30 DOI: 10.1007/s00405-025-09433-6

Sholem Hack, Shibli Alsleibi, Naseem Saleh, Eran E Alon, Naomi Rabinovics, Eric Remer

{"title":"Are chatbots a reliable source for patient frequently asked questions on neck masses?","authors":"Sholem Hack, Shibli Alsleibi, Naseem Saleh, Eran E Alon, Naomi Rabinovics, Eric Remer","doi":"10.1007/s00405-025-09433-6","DOIUrl":"10.1007/s00405-025-09433-6","url":null,"abstract":"Purpose: To evaluate the reliability and accuracy of Large Language Models in answering patient Frequently Asked Questions about adult neck masses.Methods: Twenty-four questions from the American Academy of Otolaryngology-Head and Neck Surgery were presented to ChatGPT, Claude, and Gemini. Five independent otolaryngologists evaluated responses using six criteria: accuracy, extensiveness, misleading information, resource quality, guideline citations, and overall reliability. Statistical analysis used Fisher's exact tests and Fleiss' Kappa.Results: All models showed high reliability (91.7-100%). Paid GPT and Gemini achieved highest accuracy (95.8%). Extensiveness varied significantly (p = 0.012), with Gemini scoring lowest (62.5%). Resource quality ranged from 58.3% (Claude) to 100% (Paid GPT). Guideline citations were highest for GPT models (50%) and lowest for Gemini (16.7%). Misleading information was rare (0-16.7%). Inter-rater reliability was near-perfect across five reviewers (κ = 0.95).Conclusion: Large Language Models demonstrate high reliability and accuracy for neck mass patient education, with paid versions showing marginally better performance. While promising as educational tools, variable guideline adherence and occasional misinformation suggest they should complement rather than replace professional medical advice.","PeriodicalId":11952,"journal":{"name":"European Archives of Oto-Rhino-Laryngology","volume":" ","pages":"4273-4282"},"PeriodicalIF":2.2,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143977606","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Feasibility of improving vocal fold pathology image classification with synthetic images generated by DDPM-based GenAI: a pilot study. 利用基于ddpm的GenAI合成图像改进声带病理图像分类的可行性：一项初步研究。

IF 2.2 3区医学

European Archives of Oto-Rhino-Laryngology Pub Date : 2025-08-01 Epub Date: 2025-05-17 DOI: 10.1007/s00405-025-09443-4

Iman Khazrak, Shahryar Zainaee, Mostafa M Rezaee, Mehran Ghasemi, Robert C Green

{"title":"Feasibility of improving vocal fold pathology image classification with synthetic images generated by DDPM-based GenAI: a pilot study.","authors":"Iman Khazrak, Shahryar Zainaee, Mostafa M Rezaee, Mehran Ghasemi, Robert C Green","doi":"10.1007/s00405-025-09443-4","DOIUrl":"10.1007/s00405-025-09443-4","url":null,"abstract":"Background: Voice disorders (VD) are often linked to vocal fold structural pathologies (VFSP). Laryngeal imaging plays a vital role in assessing VFSPs and VD in clinical and research settings, but challenges like scarce and imbalanced datasets can limit the generalizability of findings. Denoising Diffusion Probabilistic Models (DDPMs), a subtype of Generative AI, has gained attention for its ability to generate high-quality and realistic synthetic images to address these challenges.Purpose: This study explores the feasibility of improving VFSP image classification by generating synthetic images using DDPMs.Methods: 404 laryngoscopic images depicting VF without and with VFSP were included. DDPMs were used to generate synthetic images to augment the original dataset. Two convolutional neural network architectures, VGG16 and ResNet50, were applied for model training. The models were initially trained only on the original dataset. Then, they were trained on the augmented datasets. Evaluation metrics were analyzed to assess the performance of the models for both binary classification (with/without VFSPs) and multi-class classification (seven specific VFSPs).Results: Realistic and high-quality synthetic images were generated for dataset augmentation. The model first failed to converge when trained only on the original dataset, but they successfully converged and achieved low loss and high accuracy when trained on the augmented datasets. The best performance was gained for both binary and multi-class classification when the models were trained on an augmented dataset.Conclusion: Generating realistic images of VFSP using DDPMs is feasible and can enhance the classification of VFSPs by an AI model and may support VD screening and diagnosis.","PeriodicalId":11952,"journal":{"name":"European Archives of Oto-Rhino-Laryngology","volume":" ","pages":"4139-4153"},"PeriodicalIF":2.2,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12399448/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144086032","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Barbecue roll maneuver for horizontal canal benign paroxysmal positional vertigo: a systematic review of randomized controlled trials. 烧烤滚法治疗水平管良性阵发性位置性眩晕：随机对照试验的系统回顾。

IF 2.2 3区医学

European Archives of Oto-Rhino-Laryngology Pub Date : 2025-08-01 Epub Date: 2025-03-18 DOI: 10.1007/s00405-025-09304-0

Anas R Alashram

{"title":"Barbecue roll maneuver for horizontal canal benign paroxysmal positional vertigo: a systematic review of randomized controlled trials.","authors":"Anas R Alashram","doi":"10.1007/s00405-025-09304-0","DOIUrl":"10.1007/s00405-025-09304-0","url":null,"abstract":"Purpose: This review aims to investigate the effects of the Barbecue roll maneuver on horizontal semicircular canal benign paroxysmal positional vertigo (HC-BPPV) recovery.Methods: Multiple databases, including \"PubMed, PEDro, REHABDATA, MEDLINE, SCOPUS, EMBASE, and Web of Science\" were searched from inception to October 2024\". Experimental studies that included patients with HC-BPPV that performed the Barbecue roll maneuver independently or in combination with other treatments, compared with active, passive, or no controls, assessed HC-BPPV symptoms, were included in this analysis. The \"Physiotherapy Evidence Database (PEDro)\" scale was used to investigate the methodological quality of the included studies.Results: Nine studies met the inclusion criteria with 768 HC-BPPV patients (mean age = 56.16 years; 64% female; 52% right-side HC-BPPV; 90% geotropic HC-BPPV). The PEDro scores ranged from 3 to 8, with a median of 6. The findings showed that the Barbecue roll maneuver is not superior in reducing HC-BPPV symptoms compared to other maneuvers, such as the Gufoni, the Gufoni-Appiani and the Li repositioning.Conclusions: The initial findings indicated that the Barbecue roll maneuver is considered a treatment option for treating geotropic HC-BPPV. Performing Barbecue roll maneuver for 1 to 3 times can yield meaningful effects. Accurate diagnosis of HC-BPPV is essential for optimal treatment outcomes. The success rate of recovery depends on patient characteristics and therapist proficiency. Additional studies are recommended.","PeriodicalId":11952,"journal":{"name":"European Archives of Oto-Rhino-Laryngology","volume":" ","pages":"3883-3896"},"PeriodicalIF":2.2,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143656511","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Efficacy of vestibular rehabilitation using unidirectional rotation paradigm in VOR asymmetry: systematic review and meta-analysis. 利用单向旋转范式进行前庭康复训练对 VOR 不对称的疗效：系统综述和荟萃分析。

IF 2.2 3区医学

European Archives of Oto-Rhino-Laryngology Pub Date : 2025-08-01 Epub Date: 2025-03-18 DOI: 10.1007/s00405-025-09282-3

Miriam González-García, Lucía Prieto-Sánchez-de-Puerta, María Alharilla Montilla-Ibáñez, Emilio Domínguez-Durán, Serafín Sánchez-Gómez, Ana Sedeño-Vidal

{"title":"Efficacy of vestibular rehabilitation using unidirectional rotation paradigm in VOR asymmetry: systematic review and meta-analysis.","authors":"Miriam González-García, Lucía Prieto-Sánchez-de-Puerta, María Alharilla Montilla-Ibáñez, Emilio Domínguez-Durán, Serafín Sánchez-Gómez, Ana Sedeño-Vidal","doi":"10.1007/s00405-025-09282-3","DOIUrl":"10.1007/s00405-025-09282-3","url":null,"abstract":"Purpose: Unilateral vestibular dysfunction leads to significant asymmetry in the horizontal vestibulo-ocular reflex (VOR) during swift head movements. This reflex can be enhanced through rehabilitation exercises and visual-vestibular adaptation techniques. This systematic review aims to evaluate the current evidence on the effectiveness of unidirectional rotation treatments for improving symptoms and function in patients with vestibular disorders.Methods: A systematic review was conducted following the PRISMA 2020 guidelines, using databases such as PubMed, Cochrane Library, EMBASE, and Scopus. Included were experimental studies, randomized controlled trials (RCTs), or pilot RCTs. Meta-analysis was performed based on the findings of these studies.Results: Among 24 articles identified, three addressed the systematic review's question, two observational studies (one retrospective and one prospective) and a RCT. Studies included data from a total of 200 participants with vestibular disorders (n = 96; 48% males) for the meta-analysis. A meta-analysis, including a subgroup analysis, was conducted to assess the improvement in VOR asymmetry following vestibular rehabilitation. The analysis compared pre- and post-rehabilitation directional preponderance (DP) across three studies. Results showed a significant improvement in VOR asymmetry, with a mean difference of 18.72% in favour of rehabilitation.Conclusion: Our findings substantiate the efficacy of unilateral vestibular stimulation in reducing asymmetry in the VOR among patients with vestibular dysfunction. This modality represents a promising rehabilitation strategy, significantly enhancing vestibular function and patient outcomes.","PeriodicalId":11952,"journal":{"name":"European Archives of Oto-Rhino-Laryngology","volume":" ","pages":"3845-3853"},"PeriodicalIF":2.2,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143656514","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Treatment of Menière's disease: a scoping review of the current evidence. meni<e:1>病的治疗：对现有证据的范围审查。

IF 2.2 3区医学

European Archives of Oto-Rhino-Laryngology Pub Date : 2025-08-01 Epub Date: 2025-04-09 DOI: 10.1007/s00405-025-09329-5

Hanne Oscé, Elke Loos, Annelien Huygen, Christian Desloovere

{"title":"Treatment of Menière's disease: a scoping review of the current evidence.","authors":"Hanne Oscé, Elke Loos, Annelien Huygen, Christian Desloovere","doi":"10.1007/s00405-025-09329-5","DOIUrl":"10.1007/s00405-025-09329-5","url":null,"abstract":"Purpose: The management of unilateral Menière's disease (MD) in adult patients remains contentious, with various therapeutic options proposed but no established gold standard. This scoping review aims to evaluate the current treatment options for unilateral MD, identifying challenges in management and providing guidance for ENT physicians in selecting effective therapies.Methods: A comprehensive literature search of the MEDLINE and Embase databases was conducted without date restrictions, assessing various treatment modalities for MD. Randomized controlled trials (RCTs) were selected to ensure the highest quality of evidence was reviewed.Results: Thirty-four RCTs met the inclusion criteria. The current evidence base encompasses dietary interventions, systemic drug therapy, intratympanic treatments, positive pressure therapy, low-level laser therapy, and non-destructive surgical techniques. However, the evidence supporting these treatments is limited and inconsistent. Notably, none of the RCTs considered the heterogeneity of MD patient populations, which may explain the variability in study results.Conclusion: This review highlights the limited evidence supporting current treatments for unilateral MD, emphasizing the need for high-quality, placebo-controlled trials. Future research should incorporate biomarker-based stratification, large patient cohorts, standardized outcome measures, and long follow-up periods to enhance the consistency and comparability of findings.","PeriodicalId":11952,"journal":{"name":"European Archives of Oto-Rhino-Laryngology","volume":" ","pages":"3897-3923"},"PeriodicalIF":2.2,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143973884","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0