Francisco Esteban-Ortega, Lina Rosique-López, Jaime A Ochoa-Ríos, Rafael Rodríguez-Romero, Manuel A Burgos-Olmos
{"title":"Empty nose syndrome: new insights from a CFD approach.","authors":"Francisco Esteban-Ortega, Lina Rosique-López, Jaime A Ochoa-Ríos, Rafael Rodríguez-Romero, Manuel A Burgos-Olmos","doi":"10.1007/s00405-024-09122-w","DOIUrl":"https://doi.org/10.1007/s00405-024-09122-w","url":null,"abstract":"<p><strong>Objectives: </strong>Empty Nose Syndrome (ENS) is a debilitating condition which usually arises after aggressive turbinate reduction. However, objective tests to help in the diagnosis of this condition are lacking. Accurate diagnosis of ENS patients is critical for effective diagnosis and treatment. The article's objectives are to utilize computational fluid dynamics (CFD) to analyze nasal airflow resistance and symmetry in suspected ENS patients, classify them into distinct groups based on CFD data, and demonstrate the potential of CFD analysis in refining ENS diagnosis and guiding individualized treatment strategies.</p><p><strong>Methods: </strong>This study involved 48 patients diagnosed of ENS. However, we only considered those patients with documented prior turbinate surgery (eventually plus septal surgery), CT scan with signs of prior surgery, and a history of ENS with symptoms included in the ENS Q6. We employed computational fluid dynamics (CFD) to analyze nasal airflow resistance and symmetry. Patients were classified into three groups based on their CFD data: low resistance and normal symmetry, evident asymmetry, and normal CFD parameters.</p><p><strong>Results: </strong>Half of patients (24 out of 48) were found in the low resistance and normal symmetry group, indicating 'typical' ENS. A smaller group (8) exhibited evident asymmetry, suggesting unilateral ENS or failure of previous surgery. Finally, 16 patients whose CFD parameters are inside the normal range of flow and resistance were classified in the normal breathing group.</p><p><strong>Conclusions: </strong>Our findings highlight the value of CFD analysis in classifying ENS patients based on airflow characteristics, as CFD analysis seems helpful in refining the diagnosis of ENS. This classification system can potentially aid in tailoring individual treatment strategies and improving patient outcomes. Further research is necessary to validate these results and explore the clinical implications of different ENS subgroups.</p><p><strong>Level of evidence: </strong>Level 4 [1].</p>","PeriodicalId":11952,"journal":{"name":"European Archives of Oto-Rhino-Laryngology","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2024-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142812309","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Asma Alahmadi, Yassin Abdelsamad, Nouf A AlAmari, Mohammed Y Alyousef, Murad Al-Momani, Fahad N Altamimi, Salman F Alhabib, Abdulrahman Hagr
{"title":"Hearing implants in pediatrics with cochlear nerve deficiency: an updated systematic review.","authors":"Asma Alahmadi, Yassin Abdelsamad, Nouf A AlAmari, Mohammed Y Alyousef, Murad Al-Momani, Fahad N Altamimi, Salman F Alhabib, Abdulrahman Hagr","doi":"10.1007/s00405-024-09087-w","DOIUrl":"https://doi.org/10.1007/s00405-024-09087-w","url":null,"abstract":"<p><strong>Objective: </strong>Cochlear nerve deficiency (CND) accounts for about one-third of congenital hearing loss cases and presents several challenges during management. Currently, cochlear implant (CI) and auditory brainstem implants (ABI) represent the primary management options for CND. However, robust evidence on the outcomes of different CND management approaches remains limited. Therefore, this systematic review seeks to update and assess the effectiveness of various CND management approaches.</p><p><strong>Databases reviewed: </strong>PubMed, Scopus, Web of Science, and CENTRAL databases.</p><p><strong>Methods: </strong>We conducted an online bibliographic search across these databases. We included both interventional and observational studies evaluating CND management outcomes.</p><p><strong>Results: </strong>Of the 25 studies included, there were retrospective chart reviews, prospective observational studies, and one phase I clinical trial. Most studies focused on children with cochlear nerve aplasia or hypoplasia, with one study including patients with CHARGE syndrome. The mean age at the time of operation ranged from 0.5 to 4.5 years. Tools like the categories of auditory performance (CAP), speech intelligibility rating (SIR), and speech perception category (SPC) were commonly employed. CI outcomes were reported in 17 studies, while ABI outcomes were reported in 4 studies. The study found that the outcomes of both interventions were variable across the included studies.</p><p><strong>Conclusion: </strong>While CI is feasible and an option in children with CND, its overall effectiveness is limited in some cases like cochlear nerve aplasia. Conversely, ABI appears to be a promising alternative with better auditory, speech, and learning outcomes.</p>","PeriodicalId":11952,"journal":{"name":"European Archives of Oto-Rhino-Laryngology","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2024-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142806631","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Cortical bone total ossicular graft supported with crescent-shaped cartilage.","authors":"Ibrahim Erdim, Ismail Hologlu, Alara Izgic","doi":"10.1007/s00405-024-09131-9","DOIUrl":"https://doi.org/10.1007/s00405-024-09131-9","url":null,"abstract":"<p><strong>Purpose: </strong>This study aimed to compare the hearing outcomes of patients who underwent different type 4 tympanoplasty techniques.</p><p><strong>Methods: </strong>Patients who underwent tympanoplasty for chronic otitis media and were treated with cortical bone total ossicular prosthesis supported with crescent-shaped cartilage (Group 1), cortical bone total ossicular prosthesis (Group 2) and titanium total ossicular prosthesis (Group 3) were included in the study. Hearing outcomes were evaluated and compared with audiological tests performed before and at least 1 year after surgery.</p><p><strong>Results: </strong>There were 12 patients in Group 1 (6 males and 6 females), 14 patients in Group 2 (6 males and 8 females) and 18 patients in Group 3 (10 males and 8 females). After reconstruction, the air conduction threshold changed from 56.83 ± 13.63 to 32.25 ± 13.55 dB in Group 1, from 57.43 ± 15.3 to 40.07 ± 18.8 dB in Group 2 and from 55.39 ± 15.59 to 42.22 ± 17.32 dB in Group 3. Air-bone gap (ABG) changed from 37.58 ± 9.56 to 15.08 ± 9.58 dB in Group 1, from 36.71 ± 10.84 to 21.07 ± 11.16 dB in Group 2 and from 34.5 ± 11.72 to 22.28 ± 10.13 dB in Group 3. Preoperative and postoperative outcomes of all three groups in terms of both air conduction threshold and air-bone gap were significantly different (p < 0.01). Preoperative and postoperative changes in air conduction threshold of the three groups were also significantly different (p = 0.037). However, the differences among the three groups in terms of preoperative and postoperative changes in ABG were not significant (p = 0.057).</p><p><strong>Conclusions: </strong>Cortical bone supported with crescent-shaped cartilage total ossicular prosthesis had better hearing outcomes than other groups.</p>","PeriodicalId":11952,"journal":{"name":"European Archives of Oto-Rhino-Laryngology","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2024-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142799970","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Alexandra G L Toppenberg, Wouter L Lodder, Robert E Plaat, Leonora Q Schwandt
{"title":"Patient centered outcomes of transoral robotic surgery for obstructive sleep apnea: a retrospective analysis.","authors":"Alexandra G L Toppenberg, Wouter L Lodder, Robert E Plaat, Leonora Q Schwandt","doi":"10.1007/s00405-024-09102-0","DOIUrl":"https://doi.org/10.1007/s00405-024-09102-0","url":null,"abstract":"<p><strong>Purpose: </strong>Obstructive Sleep Apnea (OSA) is usually caused by collapse of the base of tongue (BOT) and impacts patients' overall health. Despite current conventional therapies, some patients do not achieve satisfactory results. Reduction of BOT using Trans Oral Robotic Surgery (TORS) emerges as a promising treatment. We evaluated the patient reported and clinical outcomes of TORS for OSA.</p><p><strong>Methods: </strong>We performed a retrospective cohort study of patients treated from 2018 to 2021 in a non-academic general hospital. Patients were eligible for TORS when apnea hypopnea index (AHI) was >5 in combination with obstruction at BOT level. Patients were included when 1-year follow up respiratory polygraphy was available. Changes in Epworth Sleepiness Scale (ESS), Functional Outcomes of Sleep Questionnaire (FOSQ-35), MD Anderson Dysphagia Inventory (MDADI) scores and postoperative complications were evaluated. Surgical success rates were obtained.</p><p><strong>Results: </strong>Out of 56 patients, 28 patients of which 22 (78.6%) males and 6 (21.4%) females, with OSA severity ranging from mild to severe and mean age of 49 (SD 11.8) with a median BMI of 28.1 (IQR 26.9-32.1) were included. ESS score declined from mean 5.9 (SD 3.8) to 2.2 (SD 2.0) (p<0.00). FOSQ-35 scores were all declined (p<0.05). MDADI scores were in normal range (80-100) and remained stable (p = 0.44). In 23 (82.1%) patients no postoperative complications were observed. Surgical success rates were 86%.</p><p><strong>Conclusions: </strong>TORS demonstrate to be effective and safe in OSA patients, and it can be used in both patients who are unresponsive to conventional therapies or as a primary therapy.</p>","PeriodicalId":11952,"journal":{"name":"European Archives of Oto-Rhino-Laryngology","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2024-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142799987","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The gender-related volumetric side asymmetries in sphenoid sinuses and their clinical significance.","authors":"Bulent Ozdemir, Serdar Durmaz, Ayhan Kanat, Tugba Yemis, Cihangir Ozdemir, Fatma Beyazal Celiker","doi":"10.1007/s00405-024-09134-6","DOIUrl":"https://doi.org/10.1007/s00405-024-09134-6","url":null,"abstract":"<p><strong>Background: </strong>The sphenoid sinus (SS) is important in neurosurgical practice because it is surrounded by numerous critical neurovascular structures. Using helical computerized tomography (CT) scanning, we investigated the gender-related volumetric asymmetric nature of the SS.</p><p><strong>Materials and methods: </strong>CT scans of SS of 49 (21 females, 28 males) patients admitted to the hospital between 1 October 2018 and 1 June 2019 were analyzed retrospectively. The volumes of SSs were calculated using a secondary reconstruction tool.</p><p><strong>Results: </strong>The mean age was 33,81 for females, 41,107 and in males patients which was not statistically significant. The mean right and left SS volume was 3,03 cm<sup>3</sup> and 3,.57cm<sup>3</sup> in females, but 4,28cm<sup>3</sup> and 4,70cm<sup>3</sup> in males, respectively. The difference in side asymmetry between men and women was statistically significant (p < 0.05).</p><p><strong>Conclusion: </strong>In this study, the gender-related side differences of the SS have been the first time reported in this study. The reason for this gender-related asymmetric size of the SSs may be related to the pneumatization process.</p>","PeriodicalId":11952,"journal":{"name":"European Archives of Oto-Rhino-Laryngology","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2024-12-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142791328","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Laryngeal dystonia and vocal tremor response to botulinum toxin injection.","authors":"João Viana Pinto, Isabel García López","doi":"10.1007/s00405-024-09111-z","DOIUrl":"https://doi.org/10.1007/s00405-024-09111-z","url":null,"abstract":"<p><strong>Purpose: </strong>The main objective of this study was to compare laryngeal dystonia (LD) and vocal tremor's (VT) response to botulinum toxin injection.</p><p><strong>Methods: </strong>Retrospective study including every patient with LD or VT injected with botulinum toxin guided by electromyography, from January 1, 2010, to September 30, 2022, at a tertiary hospital centre. Improvement was assessed with the VHI-10, grade of dysphonia in a visual analogue scale (VAS; 0-10), GRBAS(I) scale (0-3) and maximum phonation time (MPT).</p><p><strong>Results: </strong>A total of 77 patients were included, 44 patients with LD and 33 with VT. There were no differences between groups on pre-treatment VHI-10, grade of dysphonia in the VAS, MPT and G, R, B, A and I at diagnosis (p > 0.05). S was significantly higher in patients with LD (p < 0.001). After the first injection, both groups showed an increase in the grade of dysphonia on the VAS and a decrease in VHI-10, G, S and I (p < 0.05), with a higher variation in the VAS and S parameters in the LD group compared to VT (p < 0.05). In the 54 patients that performed two or more injections, G, S and I had a higher decrease in patients with LD when compared to patients with VT (p < 0.05).</p><p><strong>Conclusion: </strong>BTX injection was successful in improving the VHI-10, grade of dysphonia on the VAS and G, S and I in the GRBAS-I scale for both DT and VT. LD seems to have a better response to BTX in comparison to VT.</p>","PeriodicalId":11952,"journal":{"name":"European Archives of Oto-Rhino-Laryngology","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2024-12-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142791396","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Antonino Maniaci, Thomas Radulesco, Laure Santini, Pauline Pâris, Mario Lentini, Justin Michel, Nicolas Fakhry
{"title":"Impact of neck dissection in cN0 patients undergoing primary or salvage total laryngectomy.","authors":"Antonino Maniaci, Thomas Radulesco, Laure Santini, Pauline Pâris, Mario Lentini, Justin Michel, Nicolas Fakhry","doi":"10.1007/s00405-024-09126-6","DOIUrl":"https://doi.org/10.1007/s00405-024-09126-6","url":null,"abstract":"<p><strong>Introduction: </strong>It is debatable whether neck dissection is necessary in patients with advanced laryngeal carcinoma who are clinically node-negative (cN0). We assessed the effect of neck dissection on overall survival in patients with cN0 undergoing primary or salvage laryngectomy.</p><p><strong>Materials and methods: </strong>A retrospective evaluation of cN0 patients who underwent primary or salvage total/pharyngolaryngectomy at a French tertiary facility in 2008-2018, with or without neck dissection, was carried out. Patients were divided into two groups: primary (n = 65) and salvage (n = 84).</p><p><strong>Results: </strong>Comparing subglottic (HR = 3.978; p = 0.023) and hypopharyngeal (HR = 2.958; p = 0.018) malignancies to other tumor subsites, the mortality rates were greater. The primary group had a greater rate of occult metastases (23.07% vs. 14.28%; p = 0.089) than the salvage. The average lymph node ratio was significantly different between the treatment groups (0.05 ± 0.04 vs. 0.17 ± 0.33; p = 0.004). If LNR > 0.05, we found poor survival rates (p < 0.001). Although performing a neck dissection during the primary treatment increased the 5-year OS rate (Yes 89.5% vs. No 83.3%; p = 0.062), there was no discernible difference in the salvage group (Yes 80.3% vs. No 78.6%; p = 0.806; Log-rank p > 0.05). For the predicted survival variables, no significant relationships were detected in the Cox regression analysis (all p-values > 0.05).</p><p><strong>Conclusion: </strong>Although the primary group had a greater frequency of occult metastases, neither the primary group's survival outcomes nor those of the salvage laryngectomy cases were significantly affected by neck dissection. LNR and the location of the tumor were important variables that could affect survival and the choice to do a neck dissection.</p>","PeriodicalId":11952,"journal":{"name":"European Archives of Oto-Rhino-Laryngology","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2024-12-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142791374","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Tzu-Kung Wang, Ta-Jen Lee, Po-Hung Chang, Chia-Chen Wu, Chia-Hsiang Fu
{"title":"Biphenotypic sinonasal sarcoma in a toddler: a case report and literature review.","authors":"Tzu-Kung Wang, Ta-Jen Lee, Po-Hung Chang, Chia-Chen Wu, Chia-Hsiang Fu","doi":"10.1007/s00405-024-09121-x","DOIUrl":"https://doi.org/10.1007/s00405-024-09121-x","url":null,"abstract":"<p><strong>Introduction: </strong>Biphenotypic sinonasal sarcoma (BSNS) is an extremely rare malignant tumor characterized by neural and myogenic differentiation. No documented cases of BSNS have been reported in toddlers.</p><p><strong>Case report: </strong>A 1-year-11-month-old girl presented with significant unilateral nasal bleeding. Identification of the bleeding source during the initial assessment was particularly challenging given the patient's agitated state. Subsequent exploration under anesthesia revealed an exophytic tumor arising from the middle turbinate. Afterwards, the patient underwent tumor excision via transnasal endoscopy, with no immediate complications. Immunohistochemistry confirmed a diagnosis of BSNS. No signs of recurrence or distant metastasis were observed over a two-year follow-up period.</p><p><strong>Conclusion: </strong>Massive, persistent nasal bleeding due to sinonasal malignancies in very young children is exceedingly uncommon. For young patients with recurrent or atypical epistaxis, clinicians should consider a neoplastic origin, given the difficulty in pinpointing the bleeding source. This case aims to remind physicians to include such rare malignancies in differential diagnoses, stressing the need for heightened awareness during pediatric assessments.</p>","PeriodicalId":11952,"journal":{"name":"European Archives of Oto-Rhino-Laryngology","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2024-12-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142791368","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Marco Govoni, Arianna Soncini, Maria Luce Bardon, Enrico Pasanisi, Gabriele Oretti
{"title":"Dupilumab in chronic rhinosinusitis with nasal polyposis and concomitant cystic fibrosis: a real-life experience.","authors":"Marco Govoni, Arianna Soncini, Maria Luce Bardon, Enrico Pasanisi, Gabriele Oretti","doi":"10.1007/s00405-024-09125-7","DOIUrl":"https://doi.org/10.1007/s00405-024-09125-7","url":null,"abstract":"<p><strong>Purpose: </strong>Chronic rhinosinusitis (CRS) has been distinguished in primary CRS, a primary inflammatory disorder limited to airways and secondary CRS, in which the sinonasal pathology is caused by a systemic disease or a local pathologic condition. Primary CRS is in turn classified in Type 2 and Non-type 2 on the basis of the endotype and of the pattern of the immune response. Advance in the knowledge of CRS has led to new therapeutic options, among which Dupilumab (anti-IL4R). We report the clinical response to Dupilumab in two patients with cystic fibrosis and nasal polyposis, in which the coexistence of a primary and secondary CRS could not be excluded.</p><p><strong>Methods: </strong>Nasal endoscopy, smell and quality of life of the patients were evaluated at each follow-up.</p><p><strong>Results: </strong>In the first case, increased blood eosinophils, allergy to inhalants and NSAIDs intolerance supported the suspect of primary CRS with type 2 inflammatory pattern, in addition to cystic fibrosis and the therapy was effective. In the second case the patient did not show atopy or peculiar blood test and even if the phenotype could suggest a primary CRS combined with a secondary one, the treatment was ineffective and it was suspended.</p><p><strong>Conclusion: </strong>Even though classifications can be helpful, they can be reductive in cases where different aetiologies overlap. The presence of a concomitant primary CRS must not be excluded a priori in patients affected by secondary CRS. Each patient must be investigated to identify endotype characteristics and select the most appropriate therapeutic option.</p>","PeriodicalId":11952,"journal":{"name":"European Archives of Oto-Rhino-Laryngology","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2024-12-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142791372","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Arcuate eminence distance to temporal bone outer table in the middle fossa repair of superior canal dehiscence.","authors":"Hong-Ho Yang, Isaac Yang, Quinton S Gopen","doi":"10.1007/s00405-024-09067-0","DOIUrl":"https://doi.org/10.1007/s00405-024-09067-0","url":null,"abstract":"<p><strong>Purpose: </strong>To investigate the influence of arcuate eminence's distance to temporal bone outer table (AE-OT) on surgical outcomes following the middle fossa repair of superior canal dehiscence (SCD).</p><p><strong>Methods: </strong>We conducted a cohort study of consecutive repairs at a center between 2011 and 2022. AE-OT was measured on temporal bone CT imaging. Surgical outcomes were assessed with established metrics including Symptom Resolution Score (SRS), rate of Overall Symptom Improvement (OSI), and change in low-frequency air-bone gap (ΔLF-ABG) from pre- to post-surgery. Multivariable regression models assessing surgical outcomes were constructed with AE-OT as the primary predictor. Models adjusted for patient demographics, medical and surgical history, and follow-up duration.</p><p><strong>Results: </strong>A total of 402 repairs were included. Mean AE-OT was 27.1 mm (SD 2.1, range 20.8-33.9). Every mm increase in AE-OT was independently associated with a 14% reduction in odds of OSI (aOR 0.86, 95% C.I. [0.75, 0.98]) and a 4-point decrease in SRS (adj. β - 4.0 [- 6.9, - 1.1]) among frank dehiscences. AE-OT was also not associated with operative duration and ΔLF-ABG among both frank dehiscences and near dehiscences.</p><p><strong>Conclusions: </strong>Longer AE-OT predicted poorer symptomatic response but similar operative duration and audiometric improvement among frank SCD cases.</p>","PeriodicalId":11952,"journal":{"name":"European Archives of Oto-Rhino-Laryngology","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2024-12-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142791354","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}