{"title":"The role of adenoidectomy and/or tonsillectomy in the treatment of nocturnal enuresis in OSA children: a single-arm meta-analysis.","authors":"Zhe Wang, Chenhai Zheng, Yibo Hao, Yanru Duan, Xiangrong Cao, Zhiming Zhang, Jie Qin, Dahai Wu","doi":"10.1007/s00405-025-09221-2","DOIUrl":"10.1007/s00405-025-09221-2","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the efficacy of tonsillectomy and/or adenoidectomy for the treatment of nocturnal enuresis (NE) in children with obstructive sleep apnea (OSA).</p><p><strong>Methods: </strong>PubMed, Embase, the Cochrane Library, and Web of Science were searched from inception to December 2023. We included all studies of children with OSA and NE who underwent adenoidectomy and/or tonsillectomy. Risk of bias assessment and meta-analyses of included studies were performed. The sources of heterogeneity were explored through subgroup analyses.</p><p><strong>Results: </strong>The combined overall remission (OR), complete remission (CR), and partial remission (PR) were 67%, 57%, and 4%, respectively, in NE children who underwent adenoidectomy and/or tonsillectomy. Therein, the pooled OR and CR of primary nocturnal enuresis in children with OSA were 67% and 59%, respectively. The pooled OR and CR of children who were treated with adenotonsillectomy (T&A) were 72% and 65%, respectively. The pooled OR and CR of children with OSA aged > 5 years were 67% and 58%, respectively. The pooled OR and CR of postoperative follow-up of ≤ 3 months were 64% and 52%, respectively. The pooled OR and CR of NE based on RCT studies were 37.3%.</p><p><strong>Conclusion: </strong>The remission rate of NE children who underwent adenoidectomy and/or tonsillectomy was more than half. While the remission rate was significantly lower when RCT studies were included. This suggested that the actual NE remission rate may be lower than expected. Further studies with large sample sizes and control groups are expected to confirm the position of adenoidectomy and/or tonsillectomy in NE treatment.</p>","PeriodicalId":11952,"journal":{"name":"European Archives of Oto-Rhino-Laryngology","volume":" ","pages":"2843-2854"},"PeriodicalIF":1.9,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143037639","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Maximilian Gaenzle, Juergen Feisthammel, Markus Pirlich, Andreas Dietz, Matthaeus Stoehr
{"title":"Novel approach of combined endoluminal and external vacuum therapy for wound healing disorders after salvage pharyngeal reconstruction.","authors":"Maximilian Gaenzle, Juergen Feisthammel, Markus Pirlich, Andreas Dietz, Matthaeus Stoehr","doi":"10.1007/s00405-025-09227-w","DOIUrl":"10.1007/s00405-025-09227-w","url":null,"abstract":"<p><strong>Objective: </strong>Patients with recurrent head and neck carcinoma are considered for salvage surgery if resectability with clear margins is achievable. However, postoperative complications such as wound healing disorders and pharyngocutaneous fistulas remain significant challenges. While various reconstructive surgical techniques exist, supportive vacuum therapy-both external and endoluminal-has been explored as an alternative treatment modality.</p><p><strong>Type of study: </strong>We present a case report of a 60-year-old male patient with recurrent laryngeal cancer who underwent salvage laryngopharyngectomy following multiple previous surgical procedures and definitive radiochemotherapy. Due to persistent pharyngocutaneous fistula formation despite multiple reconstructions using pectoralis major flaps, an anterolateral thigh flap, and a fasciocutaneous deltopectoral flap, a novel approach combining endopharyngeal and external vacuum therapy was implemented.</p><p><strong>Results: </strong>Over six weeks, with vacuum system changes performed twice weekly, the pharyngocutaneous fistula successfully closed, leading to complete wound healing.</p><p><strong>Conclusion: </strong>This case demonstrates the potential effectiveness of a combined endopharyngeal and external vacuum therapy approach for treating persistent pharyngocutaneous fistulas when conventional surgical options are exhausted. Notably, the patient was able to resume oral food consumption following therapy, highlighting the functional benefits of this novel treatment strategy.</p>","PeriodicalId":11952,"journal":{"name":"European Archives of Oto-Rhino-Laryngology","volume":" ","pages":"3349-3355"},"PeriodicalIF":1.9,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143188601","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Middle ear secretions following spontaneous CSF leak repair may represent effusion rather than CSF leak.","authors":"Omer J Ungar, Hen Chaushu, Yahav Oron, Rani Abu-Eta, Ophir Handzel","doi":"10.1007/s00405-024-09167-x","DOIUrl":"10.1007/s00405-024-09167-x","url":null,"abstract":"<p><strong>Objective: </strong>To characterize middle ear (ME) effusion still present 2 months after repair surgery for spontaneous cerebrospinal fluid (CSF) leak via the temporal bone (TB).</p><p><strong>Study design: </strong>A retrospective chart review (2011-2022).</p><p><strong>Setting: </strong>Tertiary referral academic center.</p><p><strong>Subjects and methods: </strong>All patients with persistent ME effusion at 2 months after surgery were included in this study. The indication for surgery for spontaneous TB CSF leak was an active CSF leak with tegmen dehiscence. The presence of effusion was established by findings on microscopic otoscopy aided by tympanocentesis.ME with effusion were sampled for the presence of 𝛽2transferrin. Those negative for 𝛽2transferrin had a ventilation tube placed for ME aeration of serous otitis media (SOM). Data on persistent fluid leakage from tympanostomy tubes, presence or absence of 𝛽2transferrin in the ME, and residual air-bone gap on the postoperative audiogram were recorded.</p><p><strong>Results: </strong>Fifty-three ears underwent surgery to repair a CSF leak, 42 via a middle fossa craniotomy and 11 via transmastoid approaches. Fourteen ears (26%) still had ME effusion 2 months after surgery and it was sampled for 𝛽2transferrin. Seven were negative (SOM or mucoid OM) and the patients received a tympanostomy tube with resultant ME aeration and air-bone gap closure. The other seven underwent revision surgery.</p><p><strong>Conclusions: </strong>Postoperative ME fluid after surgery for TB CSF leak may often represent effusion by SOM rather than an ongoing or recurrent CSF leak. ME effusion by SOM is likely caused by mucosal irritation from long-standing stagnant CSF or an underlying eustachian tube dysfunction.</p>","PeriodicalId":11952,"journal":{"name":"European Archives of Oto-Rhino-Laryngology","volume":" ","pages":"2977-2981"},"PeriodicalIF":1.9,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142909361","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Zhongyan Chen, Qingling Bi, Yong Lv, Yang Liu, Yuanyuan Tian, Jianfeng Liu, Wenjing Yang, Yukun Zhou, Weiluo Huang, Yuan Li
{"title":"Exploring the relationship between electrophysiological measures of the electrically evoked auditory brainstem response and speech perception outcomes post-cochlear implantation.","authors":"Zhongyan Chen, Qingling Bi, Yong Lv, Yang Liu, Yuanyuan Tian, Jianfeng Liu, Wenjing Yang, Yukun Zhou, Weiluo Huang, Yuan Li","doi":"10.1007/s00405-024-09185-9","DOIUrl":"10.1007/s00405-024-09185-9","url":null,"abstract":"<p><strong>Objectives: </strong>This study examined the relationships between electrophysiological measures of the electrically evoked auditory brainstem response (EABR) with speech perception measured in quiet after cochlear implantation (CI) to identify the ability of EABR to predict postoperative CI outcomes.</p><p><strong>Methods: </strong>Thirty-four patients with congenital prelingual hearing loss, implanted with the same manufacturer's CI, were recruited. In each participant, the EABR was evoked at apical, middle, and basal electrode locations. The following EABR measures were analyzed: wave III and V input/output (I/O) function, latency, threshold, threshold<sub>0.5 μV</sub> and Gibson scoring. Patients' speech perception abilities were assessed using the Mandarin Speech Perception (MSP) materials presented in quiet. The Categories of Auditory Performance (CAP) and Speech Intelligibility Rating (SIR) were also used to assess CI outcomes. A regression model was developed to explore the relationship between EABR and each speech measure, to identify parameters with significant predictive ability.</p><p><strong>Results: </strong>A significantly shorter eV latency, lower eV threshold, lower eV threshold<sub>0.5 μV</sub> and steeper I/O slopes for both eV and eIII were observed when these responses were evoked at the apical electrode, compared to the middle and basal positions. Implantation age was significantly negatively correlated with bisyllables recognition rate (R<sup>2</sup> = 0.20, p = 0.0194). The eIII slope at the apical site and the eV slope at the basal site demonstrated the highest R2 values in positive correlation with CAP, both with R<sup>2</sup> = 0.09. Among the EABR parameters, the regression models based on MSP bisyllables recognition rate, basal eV latency, eV thresholds and threshold<sub>0.5 μV</sub> recorded at the apical and middle positions were statistically significant.</p><p><strong>Conclusions: </strong>Our study identified an apex-to-base gradient in EABR responsiveness following prolonged CI use. The threshold and I/O slopes of EABR appear to be informative predictors of speech perception performance in CI users, especially in the low-to-middle frequency range. However, further validation is needed.</p>","PeriodicalId":11952,"journal":{"name":"European Archives of Oto-Rhino-Laryngology","volume":" ","pages":"3005-3017"},"PeriodicalIF":1.9,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142920816","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Correction: Is there any room for ChatGPT AI bot in speech-language pathology?","authors":"Namık Yücel Birol, Hilal Berber Çiftci, Ayşegül Yılmaz, Ayhan Çağlayan, Ferhat Alkan","doi":"10.1007/s00405-025-09363-3","DOIUrl":"10.1007/s00405-025-09363-3","url":null,"abstract":"","PeriodicalId":11952,"journal":{"name":"European Archives of Oto-Rhino-Laryngology","volume":" ","pages":"3281"},"PeriodicalIF":1.9,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143985627","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Giannicola Iannella, Annalisa Pace, Antonio Greco, Armando De Virgilio, Mario Giuseppe Bellizzi, Enrica Croce, Jerome R Lechien, Antonino Maniaci, Salvatore Cocuzza, Federico Gioacchini, Massimo Re, Andrea Collettini, Lodovica Gatti, Tiziano Perrone, François Simon, Stéphane Gargula, Giuseppe Magliulo
{"title":"The SAPIENS 3D-printed temporal bone model: a real tool for advanced otologic surgery education.","authors":"Giannicola Iannella, Annalisa Pace, Antonio Greco, Armando De Virgilio, Mario Giuseppe Bellizzi, Enrica Croce, Jerome R Lechien, Antonino Maniaci, Salvatore Cocuzza, Federico Gioacchini, Massimo Re, Andrea Collettini, Lodovica Gatti, Tiziano Perrone, François Simon, Stéphane Gargula, Giuseppe Magliulo","doi":"10.1007/s00405-024-09199-3","DOIUrl":"10.1007/s00405-024-09199-3","url":null,"abstract":"<p><strong>Objective: </strong>Our study focused on the development and evaluation of the SAPIENS (Specific Anatomical Printed-3D-model In Education and New Surgical Simulations) as a valid tool for otologic surgical education.</p><p><strong>Methods: </strong>Twenty junior otolaryngologist surgeons in training were enrolled in the study. Each participant was invited to perform dissection of three different temporal bones. 1)Transparent 3-D printed model; 2)Opaque 3-D model; 3)fresh frozen human temporal bone. Following their drilling experience, participants answered to two specific questionnaires. The first was a questionnaire developed by Mowry et al. to evaluate 3D models in its general characteristics of anatomy and dissection, while the second one was a questionnaire specifically designed to compare the 3-D printed models with the human fresh frozen temporal bone.</p><p><strong>Results: </strong>The average total score of the questionnaire was calculated as 53.2/61 in transparent 3-D model and 55.4/61 in the opaque 3-D model. These values indicate that the 3D printed models closely resemble the human TB in terms of anatomy and dissection. Comparisons of the 3D model and human TB were rated as very similar in all surgical steps. The total score was 4/5 in the transparent 3-D model and 4.2/5 in the opaque 3-D model.</p><p><strong>Conclusion: </strong>We have designed and developed a 3D-printed model of the temporal bone that closely resembles the human temporal bone. The SAPIENS 3-D printed temporal bone model could be considered a valuable tool for advancing oto-surgical education due to its similarity to the human temporal bone in terms of anatomy and dissection.</p>","PeriodicalId":11952,"journal":{"name":"European Archives of Oto-Rhino-Laryngology","volume":" ","pages":"3051-3063"},"PeriodicalIF":1.9,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143440370","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Okikioluwa Stephen Aladeyelu, Peter Michael Burge, Peterson Makinde Atiba, Anil Madaree, Lelika Lazarus
{"title":"Paranasal sinus mucoceles and its distortion of craniofacial-orbital anatomy: a narrative synthesis.","authors":"Okikioluwa Stephen Aladeyelu, Peter Michael Burge, Peterson Makinde Atiba, Anil Madaree, Lelika Lazarus","doi":"10.1007/s00405-024-09174-y","DOIUrl":"10.1007/s00405-024-09174-y","url":null,"abstract":"<p><strong>Purpose: </strong>To explore available literature on PNS mucoceles and its distortions of craniofacial-orbital anatomy with regard to orbital bony defects and ophthalmic manifestations, highlighting the PNS mucoceles that mostly result in these distortions.</p><p><strong>Methods: </strong>A comprehensive literature search was conducted in June 2024 for available literature on the subject matter viz.; Google Scholar, PubMed and Medline, and Cochrane Library. Eligible studies were subjected to bias assessment. Extracted data from eligible studies were synthesized using narrative synthesis.</p><p><strong>Results: </strong>Eighteen studies met the inclusion criteria. The 18 studies correspond to a total of 638 patients diagnosed with different types of PNS mucoceles, with males being the highest incidence of patients. Frontal, ethmoid, and fronto-ethmoidal mucoceles had the highest incidences (26.36%, 24.03%, and 23.29%, respectively). Orbital-bony defects, such as disruption and breach of the lamina papyracea, orbital wall erosion, and skull base erosion, were reported as the damage mostly caused by frontal and ethmoidal mucoceles. Ophthalmic manifestations such as proptosis, diplopia, ptosis, preorbital swelling, epiphora, vision problems, and exophthalmos were reported to occur in any type of the PNS mucoceles but are more common in mucoceles in the anterior sinuses.</p><p><strong>Conclusions: </strong>The narrative review summarizes the distortion of PNS mucoceles to craniofacial-orbital anatomy. Findings from this review will help to create more awareness of the extent of possible distortion that PNS mucoceles could have on craniofacial-orbital anatomy.</p>","PeriodicalId":11952,"journal":{"name":"European Archives of Oto-Rhino-Laryngology","volume":" ","pages":"2799-2810"},"PeriodicalIF":1.9,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143002412","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Volume-viscosity swallow test to facilitate individualized dietary modifications for dysphagia following intracerebral hemorrhage.","authors":"Roger W Chan, Shuiqin Fu, Yue Zhang, Lei Shi","doi":"10.1007/s00405-025-09242-x","DOIUrl":"10.1007/s00405-025-09242-x","url":null,"abstract":"<p><strong>Purpose: </strong>This study examined the effects of individualized dietary modifications based on the volume-viscosity swallow test (V-VST) on functional oral intake, incidence of pneumonia, and swallowing-related quality of life in individuals with intracerebral hemorrhage.</p><p><strong>Methods: </strong>One hundred and seven participants with signs of dysphagia in the acute and early subacute phases of stroke following intracerebral hemorrhage were randomly assigned into an experimental group for individualized dietary modifications based on V-VST plus routine standard care (n = 53), and a control group for routine care alone (n = 54). Incidence of pneumonia, functional oral intake scale (FOIS) ratings and Eating Assessment Tool (EAT-10) scores before and after intervention were evaluated.</p><p><strong>Results: </strong>A significantly lower incidence of pneumonia was found in the experimental group than in the control group (p < 0.05). Significant group differences were found in functional oral intake and in quality of life, with significantly higher FOIS ratings and significantly lower EAT-10 scores in the experimental group post-intervention (p < 0.001).</p><p><strong>Conclusion: </strong>These findings suggested that despite being a noninstrumental screening tool, V-VST could facilitate individualized dietary modifications and could be an effective clinical option for reducing the risk of pneumonia, improving functional oral intake and enhancing quality of life in individuals with dysphagia following intracerebral hemorrhage. Future studies should explore how dietary modifications could be more precisely implemented based on the International Dysphagia Diet Standardization Initiative framework.</p>","PeriodicalId":11952,"journal":{"name":"European Archives of Oto-Rhino-Laryngology","volume":" ","pages":"3245-3256"},"PeriodicalIF":1.9,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143036901","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Preadmission systemic antibiotic treatment in necrotizing otitis externa (NOE).","authors":"Sharifah Sara Syed Badrol, Oren Ziv, Chilaf Peled","doi":"10.1007/s00405-024-09161-3","DOIUrl":"10.1007/s00405-024-09161-3","url":null,"abstract":"<p><strong>Purpose: </strong>Necrotizing otitis externa (NOE) is a serious life-threatening infection, with Pseudomonas (PA) aeruginosa being the primary causative agent. Over the last two decades the use of systemic anti-PA antibiotics expanded substantially and are now prescribed regularly by physicians. Meanwhile, studies indicate shifting trends in the incidence of the offending pathogen in NOE. The objective of the study is to assess whether preadmission antibiotic treatment influence the incidence offending pathogens and sterile cultures in NOE. Also, we aim to evaluate the effects of preadmission antibiotic treatment on NOE severity and disease progression.</p><p><strong>Methods: </strong>A retrospective case series analysis was performed, including all patients admitted in a single tertiary center due to NOE.</p><p><strong>Results: </strong>83 patients were included in the study. Among them 17 patients received no oral antibiotics prior to admission (NoAb-NOE), and 65 patients received systemic antibiotics prior to admission. There was no statistical difference between the groups regarding the incidence of the pathogen or sterile culture. Furthermore, there was no statistical difference regarding duration of hospitalization, need for surgery or readmission.</p><p><strong>Conclusion: </strong>Preadmission antibiotic treatment does not influence the incidence of offending pathogens or rate of sterile culture in NOE. Moreso, preadmission antibiotic has no effect on disease progression or severity in NOE. Our findings suggest that sterile culture NOE is probably due to the low sensitivity of superficial swabs and not secondary to partially treated disease. Deep tissue culture should be considered in the setting of NOE patients.</p>","PeriodicalId":11952,"journal":{"name":"European Archives of Oto-Rhino-Laryngology","volume":" ","pages":"2921-2925"},"PeriodicalIF":1.9,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142885425","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}