European Archives of Oto-Rhino-Laryngology最新文献

{"title":"Hyperacusis in gifted children and its impact on quality of life.","authors":"Banu Baş, Rukiye Çolak Sivri","doi":"10.1007/s00405-025-09389-7","DOIUrl":"10.1007/s00405-025-09389-7","url":null,"abstract":"<p><strong>Purpose: </strong>The aim of this study is to determine the presence of hyperacusis in gifted children and evaluate its effect on quality of life.</p><p><strong>Methods: </strong>The study included 47 children between the ages of 7 and 12 who did not have hearing loss, who were diagnosed as gifted by scoring 120 or more on the Weschler Intelligence Scale for Children-IV (WISC-IV) and who did not have any accompanying disabilities, and 27 age and gender matched children with normal intelligence.The 'Pediatric Hyperacusis Questionnaire Parent Form(P-HQ)' was applied to the children for hyperacusis assessment, and the 'Quality of Life Inventory for Children (PedsQL)' was applied for quality of life.</p><p><strong>Results: </strong>When the pediatric hyperacusis questionnaire parent form scores were compared between the groups, a statistically significant difference was obtained (p =.000).In the quality of life assessment made using the quality of life scale for children, a statistically significant difference was obtained between the groups in the sub-parameters of the test; physical health total score (p =.000),emotional functioning score (p =.032),social functioning score (p =.007),school functioning score (p =.000) and scale total score (p =.000).</p><p><strong>Conclusion: </strong>Our study results showed that gifted children mostly complain of hyperacusis and that this complaint increases as their intelligence level increases.We believe that hyperacusis and its effect on quality of life should not be ignored in gifted children.Whenever possible, gifted children should be evaluated for hyperacusis and sensory sensitivities.We think that individualized therapy planning is necessary for the difficulties caused by sensory sensitivities that affect quality of life. Our findings revealed the necessity of hyperacusis assessment and therapy when working with gifted individuals.</p>","PeriodicalId":11952,"journal":{"name":"European Archives of Oto-Rhino-Laryngology","volume":" ","pages":"3303-3309"},"PeriodicalIF":1.9,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12122583/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143963375","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hamartomas of the nasal cavity: a case series and review of the literature.","authors":"Ahlam H Alamri, Mohammed Alswayyed, Fatma Alenazy, Rayan Alfallaj, Saad Alasmari, Abdulrahman Aljofan, Ahmad S Alroqi","doi":"10.1007/s00405-025-09291-2","DOIUrl":"10.1007/s00405-025-09291-2","url":null,"abstract":"<p><strong>Purpose: </strong>Respiratory epithelial adenomatoid hamartoma (REAH) is an infrequently encountered noncancerous growth. Hamartomas are characterized by excessive pseudoglandular proliferation of the ciliated respiratory epithelium originating from the surface of the respiratory epithelium.</p><p><strong>Methods: </strong>In this retrospective series, we present three cases of Saudi patients diagnosed with REAH between 2015 and 2023. We summarize patient demographics, clinical presentation, radiological features, histopathological characteristics, treatment modalities, and outcomes to enhance the understanding of REAH, inform clinical management strategies, and provide an updated literature review.</p><p><strong>Results: </strong>Our patient population (male, 2; female, 1) had a mean age of 44 years and exhibited REAH at various locations in the nasal cavity. All three patients were treated surgically, without recurrence during the follow-up period.</p><p><strong>Conclusion: </strong>This series contributes to the growing body of evidence that, although rare, REAH may be more common than previously thought, necessitating awareness among clinicians for better patient outcomes.</p>","PeriodicalId":11952,"journal":{"name":"European Archives of Oto-Rhino-Laryngology","volume":" ","pages":"3363-3368"},"PeriodicalIF":1.9,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143633831","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Rapid acclimatization to baseline stimulation with a multi-canal vestibulocochlear implant.","authors":"B L Vermorken, S C J van Boxel, B Volpe, N Guinand, A Pérez Fornos, E M J Devocht, R van de Berg","doi":"10.1007/s00405-024-09184-w","DOIUrl":"10.1007/s00405-024-09184-w","url":null,"abstract":"<p><strong>Purpose: </strong>It is hypothesized that a vestibular implant should re-establish baseline activity of the ampullary nerves. Use of a constant baseline stimulation potentially allows encoding of bi-directional head movements, through the addition of signal modulations. Effective stimulation of the vestibular nerves depends on the ability to acclimate to this baseline signal. This study aims to measure eye movement responses and evaluate patient perception after turning ON and OFF single-canal and multi-canal baseline stimulation with a vestibulocochlear implant.</p><p><strong>Methods: </strong>Nine subjects with a multi-canal vestibulocochlear implant were investigated by turning baseline stimulation ON and OFF. Eye movements were recorded at fixed time points. To quantify acclimatization, both the relative time constant (time until the nystagmus decreases to 37% of its initial maximum value) and the absolute time constant (time until the velocity drops below 5°/s) were calculated. Following each recording, patients' perceptions were collected.</p><p><strong>Results: </strong>A rapid logarithmic decay in response dynamics was observed in all subjects after turning baseline stimulation ON and OFF. Full acclimatization was typically achieved within one minute. The response dynamics were reproducible when tested twice and were comparable when using a stimulation rate of either 100% or 50%. In general, turning baseline stimulation OFF resulted in lower response dynamics compared to ON.</p><p><strong>Conclusion: </strong>The ability to quickly acclimate to step changes in stimulation amplitude level is beneficial and suggests the presence of efficient neuronal processes that aid in the process of dual-state adaptation. Rapid acclimatization paves the way for safe and convenient use of the implant.</p><p><strong>Trial registration number and date: </strong>ClinicalTrials.gov: NCT04918745. Registered 28 April 2021.</p>","PeriodicalId":11952,"journal":{"name":"European Archives of Oto-Rhino-Laryngology","volume":" ","pages":"2991-3003"},"PeriodicalIF":1.9,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12122573/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143064731","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Anatomical investigation of safety determining factors for keyhole drilling trajectories for robotic cochlear implant surgery.","authors":"Saliha Seda Adanır, Piraye Kervancıoğlu, İlhan Bahşi, Mohammad Al Saadi, Paul Van de Heyning, Vedat Topsakal","doi":"10.1007/s00405-024-09198-4","DOIUrl":"10.1007/s00405-024-09198-4","url":null,"abstract":"<p><strong>Purpose: </strong>Cochlear implants (CI) are the most successful bioprosthesis in medicine probably due to the tonotopic anatomy of the auditory pathway and of course the brain plasticity. Correct placement of the CI arrays, respecting the inner ear anatomy are therefore important. The ideal trajectory to insert a cochlear implant array is defined by an entrance through the round window membrane and continues as long as possible parallel to the basal turn of the cochlea. Image-guided surgery can directly drill with a robotic arm through the mastoid and execute an exact drilling of this precalculated most ideal trajectory. Here, we aim to identify critical anatomical structures determining the safest keyhole drilling trajectory by comparing easy and difficult CI surgeries performed with the HEARO Procedure: a robotic tool for image-guided surgery.</p><p><strong>Methods: </strong>Cone-beam computed tomography images of patients who underwent robot-assisted cochlear implantation surgery (RACIS) were included. Three of 25 cases had to be converted to conventional surgery because of the current safety mitigations based on anatomical distance. Radiological images in DICOM format were transferred to dedicated software (OTOPLAN® Cascination GMHB Bern Switzerland) for analyses. Surgical segmentation and previously planned trajectories were analyzed for these 25 cases by comparing cochlear sizes, facial recess sizes, round window sizes, and trajectory angles. In addition, facial recess angle, and cochlear orientation angles were measured with RadiAnt DICOM Viewer (Medixant, Pozan, Poland).</p><p><strong>Results: </strong>Facial recess size, facial recess angle, and distance between the facial nerve and safe trajectory were smaller in patient who converted from robotic surgery to conventional. A significant positive correlation existed between basal turn angle and in-plane angle (p = 0.001, r = 0.859). In addition, there was a significant negative correlation between the basal turn length and the last electrode insertion depth degree (p = 0.007, r = 0.545).</p><p><strong>Conclusion: </strong>In our robotic surgery cases, we demonstrate that the limiting factors of anatomical relationships are constituted by the dimensions of the facial recess and the cochlear orientation. The findings of this study are considered to be a reference for future studies in achieving collision-free trajectory planning in robotic-assisted cochlear implant surgery.</p>","PeriodicalId":11952,"journal":{"name":"European Archives of Oto-Rhino-Laryngology","volume":" ","pages":"3037-3050"},"PeriodicalIF":1.9,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12122655/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143002392","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Harnessing advanced large language models in otolaryngology board examinations: an investigation using python and application programming interfaces.","authors":"Cosima C Hoch, Paul F Funk, Orlando Guntinas-Lichius, Gerd Fabian Volk, Jan-Christoffer Lüers, Timon Hussain, Markus Wirth, Benedikt Schmidl, Barbara Wollenberg, Michael Alfertshofer","doi":"10.1007/s00405-025-09404-x","DOIUrl":"10.1007/s00405-025-09404-x","url":null,"abstract":"<p><strong>Purpose: </strong>This study aimed to explore the capabilities of advanced large language models (LLMs), including OpenAI's GPT-4 variants, Google's Gemini series, and Anthropic's Claude series, in addressing highly specialized otolaryngology board examination questions. Additionally, the study included a longitudinal assessment of GPT-3.5 Turbo, which was evaluated using the same set of questions one year ago to identify changes in its performance over time.</p><p><strong>Methods: </strong>We utilized a question bank comprising 2,576 multiple-choice and single-choice questions from a German online education platform tailored for otolaryngology board certification preparation. The questions were submitted to 11 different LLMs, including GPT-3.5 Turbo, GPT-4 variants, Gemini models, and Claude models, through Application Programming Interfaces (APIs) using Python scripts, facilitating efficient data collection and processing.</p><p><strong>Results: </strong>GPT-4o demonstrated the highest accuracy among all models, particularly excelling in categories such as allergology and head and neck tumors. While the Claude models showed competitive performance, they generally lagged behind the GPT-4 variants. A comparison of GPT-3.5 Turbo's performance revealed a significant decline in accuracy over the past year. Newer LLMs displayed varied performance levels, with single-choice questions consistently yielding higher accuracy than multiple-choice questions across all models.</p><p><strong>Conclusion: </strong>While newer LLMs show strong potential in addressing specialized medical content, the observed decline in GPT-3.5 Turbo's performance over time underscores the necessity for continuous evaluation. This study highlights the critical need for ongoing optimization and efficient API usage to improve LLMs potential for applications in medical education and certification.</p>","PeriodicalId":11952,"journal":{"name":"European Archives of Oto-Rhino-Laryngology","volume":" ","pages":"3317-3328"},"PeriodicalIF":1.9,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12122622/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143974340","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ultra-high-resolution CT of the temporal bone before cochlear implantation for pre-operative prediction of chorda tympani nerve management and round window access.","authors":"Fatma Boubaker, Ulysse Puel, Sara Imbs, Gabriela Hossu, Alain Blum, Pedro Augusto Gondim Teixeira, Michael Eliezer, Cécile Parietti-Winkler, Romain Gillet","doi":"10.1007/s00405-025-09231-0","DOIUrl":"10.1007/s00405-025-09231-0","url":null,"abstract":"<p><strong>Background and purpose: </strong>To evaluate various anatomical parameters and their relationship to chorda tympani nerve (CTN) injury and round window (RW) access during cochlear implantation.</p><p><strong>Materials and methods: </strong>Ultra-high-resolution CT images of 66 patients were retrospectively reviewed and compared with operative reports. The facial recess and the round window were analyzed, mainly using the chorda-facial angle (CFA), the width of the facial recess, the CTN-tympanic annulus distance, the RW-mastoid portion of the facial nerve angle, and the type of RW.</p><p><strong>Results: </strong>Surgical management of the CTN was uneventful in 59 patients, whereas surgical difficulty occurred in 7, with significant differences only between the CTN-tympanic annulus distance and the RW-mastoid portion of the facial nerve angle (P ≤ 0.04). The optimal cut-off values for predicting surgical difficulty were 0.95 mm and 19°, respectively, with sensitivity, specificity, positive, and negative predictive values of 0.71, 0.67, 0.2 and 0.95 for the distance, and 0.57, 0.95, 0.57 and 0.94 for the angle, respectively. The RW was accessible in 51 patients and cochleostomy was performed in 15 patients, without significant difference between radiological parameters, especially concerning the CFA.</p><p><strong>Conclusion: </strong>A CTN-tympanic annulus distance greater than 0.95 mm may help to predict a non-negligible risk of CTN surgical damage, and a RW thinner than 1.85 mm may require exploring the possibility of a cochleostomy approach.</p>","PeriodicalId":11952,"journal":{"name":"European Archives of Oto-Rhino-Laryngology","volume":" ","pages":"3065-3073"},"PeriodicalIF":1.9,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143037640","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Surgical consideration and practical difficulty in malignant otitis externa: a systematic review.","authors":"Mariam Aljehani, Rayan Alhussaini, Abdulrhman Alsanosi","doi":"10.1007/s00405-024-09175-x","DOIUrl":"10.1007/s00405-024-09175-x","url":null,"abstract":"<p><strong>Purpose: </strong>This systematic review aims to explore the role of surgery in managing Malignant Otitis Externa (MOE) by analyzing surgical considerations, treatment duration, responses, and patient outcomes.</p><p><strong>Methods: </strong>A comprehensive search was conducted across PubMed, Science Direct, Google Scholar, and Cochrane Library databases between 2003 and February 2023. Studies meeting inclusion criteria detailed MOE cases, patient medical profiles, surgical procedures undertaken, and treatment outcomes. Selection criteria emphasized surgical aspects and patient-related outcomes in MOE.</p><p><strong>Results: </strong>Twenty-two articles published from 2006 to 2023, encompassing 901 predominantly male participants, were included. Studies fell into quantitative descriptive (e.g., case series) and non-randomized quantitative categories (e.g., cohort studies). Surgery was primarily performed due to failed conservative treatments, complications like skull base osteomyelitis, and disease progression. Surgical interventions, notably debridement and mastoidectomy (n = 15), were detailed, with varied survival and mortality rates among studies.</p><p><strong>Conclusion: </strong>Prompt identification and effective management are crucial for MOE, a rapidly advancing condition. Surgical intervention emerged as the preferred treatment option for critically affected MOE patients, especially in cases of failed conservative measures, complications, and disease progression.</p>","PeriodicalId":11952,"journal":{"name":"European Archives of Oto-Rhino-Laryngology","volume":" ","pages":"2811-2820"},"PeriodicalIF":2.2,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143002483","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy and safety of platelet-rich fibrin combined with diced cartilage in rhinoplasty: a systematic review and meta-analysis.","authors":"Salmah M Alharbi, Ghaida H Alotaibi, Ali A Alshehri, Ali J Asiry, Mohammed S Alahmari","doi":"10.1007/s00405-025-09240-z","DOIUrl":"10.1007/s00405-025-09240-z","url":null,"abstract":"<p><strong>Purpose: </strong>The purpose of this study was to evaluate the efficacy and safety of combining platelet-rich fibrin (PRF) with diced cartilage (DC) in patients undergoing rhinoplasty.</p><p><strong>Methods: </strong>A systematic search of MEDLINE/PubMed, Cochrane Library, Web of Science, and Scopus was conducted, including studies published through August 9, 2024. We included observational studies and clinical trials of rhinoplasty using the DC technique with PRF. Primary outcomes were cartilage resorption, nasal dorsum/tip irregularity, and patient satisfaction. Secondary outcomes included postoperative complications such as edema, hematoma, infection, erythema, displacement, and extrusion. Risk of bias (ROB) was assessed using the ROB2 tool for randomized trials and the MINORS checklist for observational studies.</p><p><strong>Results: </strong>Seven studies with 286 participants were included. Results showed minimal cartilage resorption in five studies. The pooled incidences of nasal dorsum/tip irregularity, erythema, and displacement were 0.43% [95% CI: 0.00-1.95%], 1.63% [95% CI: 0.00-4.99%], and 0.63% [95% CI: 0.00-2.22%], respectively. Patient satisfaction was high, with a pooled rate of 94.33% [95% CI: 89.28-99.38%].</p><p><strong>Conclusion: </strong>The addition of PRF to DC in rhinoplasty was associated with favorable postoperative outcomes and high patient satisfaction, with a low incidence of complications. However, the lack of comparative studies makes it difficult to determine whether PRF provides significant benefits over DC alone. Larger randomized controlled trials with longer follow-up are needed to further validate these findings.</p>","PeriodicalId":11952,"journal":{"name":"European Archives of Oto-Rhino-Laryngology","volume":" ","pages":"2887-2897"},"PeriodicalIF":2.2,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143074258","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Analytical review of facial nerve palsy following SARS-CoV-2 vaccination: comprehensive assessment.","authors":"Ahmad A Mirza, Abdulaziz H Almalki, Zaid AlMubarak, Jennifer L Spiegel, Valerie Dahm, Vincent Y Lin","doi":"10.1007/s00405-024-09173-z","DOIUrl":"10.1007/s00405-024-09173-z","url":null,"abstract":"<p><strong>Purpose: </strong>The SARS-CoV-2 vaccination has reduced COVID-19 infection, though facial nerve palsy (FNP) has emerged as a notable side effect of the vaccine. We evaluated the current literature on the clinical presentation and outcomes of FNP related to COVID-19 vaccination.</p><p><strong>Methods: </strong>A comprehensive search of seven databases was conducted for studies up to January 2023. We included individually reported patients on FNP following COVID-19 vaccination, while cases with co-existing neurological disorders or secondary causes of FNP were excluded. Pooled descriptive and inferential analyses were conducted, with prognostic factors evaluated through regression and Kaplan-Meier survival analysis.</p><p><strong>Results: </strong>A total of 33 studies were included, with data from 52 patients who developed post-COVID-19 vaccination FNP (PV-FNP). Most cases (71%) followed mRNA vaccines, primarily occurring after the first dose and within the first week post-vaccination. Nearly all cases (98%) were unilateral, with Grade III palsy being most common. Complete recovery was achieved in 55% of patients, significantly lower than pre-pandemic rate (83%). A longer latency period was associated with a reduced likelihood of full recovery, and females experienced faster recovery compared to males.</p><p><strong>Conclusion: </strong>FNP following SARS-CoV-2 vaccination tends to present as mild and unilateral, with a lower full recovery rate compared to pre-pandemic cases. Symptoms often develop within the first week after vaccination, and earlier symptom onset is associated with a higher likelihood of full recovery. Recognizing these patterns provides valuable guidance for clinicians in counseling patients about prognosis and managing follow-up care effectively.</p>","PeriodicalId":11952,"journal":{"name":"European Archives of Oto-Rhino-Laryngology","volume":" ","pages":"2787-2797"},"PeriodicalIF":1.9,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142946815","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Unveiling the relation between swallowing muscle mass and skeletal muscle mass in head and neck cancer patients.","authors":"Javier Hurtado-Oliva, Lucy Núñez-Miranda, Aniek T Zwart, Jeroen Vister, Boudewijn E C Plaat, Roel J H M Steenbakkers, Anouk van der Hoorn, Inge Wegner, Gyorgy B Halmos","doi":"10.1007/s00405-025-09207-0","DOIUrl":"10.1007/s00405-025-09207-0","url":null,"abstract":"<p><strong>Purpose: </strong>Sarcopenia, characterized by loss of skeletal muscle mass (SMM) and strength, often leads to dysphagia in the elderly. This condition can also worsen treatment outcomes in head and neck cancer (HNC) patients, who are susceptible to swallowing difficulties. This study aimed to establish the correlation between swallowing muscle mass (SwMM) and SMM in HNC patients.</p><p><strong>Methods: </strong>Data from 157 HNC patients in the OncoLifeS biobank of the University Medical Center Groningen were analyzed using pre-treatment neck CT scans. The SwMM was assessed by the cross-sectional area (CSA) of the tongue complex muscles (TCM), and SMM was indicated by the skeletal muscle index (SMI), calculated from corrected CSA at the third lumbar vertebra (L3). Correlations between SwMM and SMM were analyzed using Pearson or Spearman tests, and multivariable linear regression with SMI as dependent variable was performed.</p><p><strong>Results: </strong>SwMM was moderately correlated with SMI (r = 0.600, p < 0.001), CSA at C3 (r = 0.538, p < 0.001), and CSA at L3 (r = 0.651, p < 0.001). The CSA at C3 strongly correlated with SMI (r = 0.871, p < 0.001). In multivariable regression analysis, age, sex, and weight were strong predictors of SMI, while the TCM area was a less robust predictor (p = 0.059). Models with CSA at C3 and L3 showed all variables as significant predictors (p < 0.001).</p><p><strong>Conclusions: </strong>Although SwMM was significantly correlated with SMI and holds clinical utility, it is not strong enough to be considered interchangeably with C3 for predicting SMI, suggesting that swallowing muscles represent a different entity than skeletal muscles and not reflect accurately the general muscle mass.</p>","PeriodicalId":11952,"journal":{"name":"European Archives of Oto-Rhino-Laryngology","volume":" ","pages":"3173-3182"},"PeriodicalIF":1.9,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12122628/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143036829","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}