Epilepsy & Behavior最新文献

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My epilepsy and Me: Hearing from adults with intellectual disability 我的癫痫和我:来自智障成人的聆听
IF 2.3 3区 医学
Epilepsy & Behavior Pub Date : 2025-10-02 DOI: 10.1016/j.yebeh.2025.110745
Carrie Grennan , Christine Linehan
{"title":"My epilepsy and Me: Hearing from adults with intellectual disability","authors":"Carrie Grennan ,&nbsp;Christine Linehan","doi":"10.1016/j.yebeh.2025.110745","DOIUrl":"10.1016/j.yebeh.2025.110745","url":null,"abstract":"<div><div>People with intellectual disability make up a significant percentage of those with epilepsy. The co-occurrence of these conditions presents distinct challenges in terms of health literacy and accessing healthcare. Easy-read documents have been proposed as a means to improve health literacy and facilitate engagement in healthcare for people with intellectual disability. This study aimed to interview people with these co-occurring conditions directly about their experiences and opinions regarding their experience with epilepsy and where and how they access epilepsy related information and healthcare, specifically easy ready materials. Reflexive thematic analysis was used to analyse interview transcripts and identified three themes and five sub-themes within participant responses. The primary themes were 1) Lifelines Matter − referring to how the knowledge of healthcare options and seizure management strategies impacts upon perceived overall experience of epilepsy, 2) Doctors are Indifferent, which encapsulated how participants interpret their interactions with healthcare professionals and 3) We Want Information, which spoke to participants’ enthusiasm to learn more about their epilepsy and engage more meaningfully in their healthcare planning. These results were consistent with, and provided additional context when considered alongside, previous literature. This study was novel in its exploration of the topic of health literacy as it relates to people with intellectual disability and epilepsy. Future research should aim to consult people with intellectual disability and epilepsy on the development and implementation of easy-read materials in healthcare and assess how the implementation of these materials may impact upon health literacy and, furthermore, overall healthcare experiences for this group.</div></div>","PeriodicalId":11847,"journal":{"name":"Epilepsy & Behavior","volume":"172 ","pages":"Article 110745"},"PeriodicalIF":2.3,"publicationDate":"2025-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145216661","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A guide to systematic reviews and meta-analyses in the field of epilepsy 癫痫领域的系统综述和荟萃分析指南
IF 2.3 3区 医学
Epilepsy & Behavior Pub Date : 2025-10-02 DOI: 10.1016/j.yebeh.2025.110733
Nathan A. Shlobin , Michael Kinney , Francesco Brigo
{"title":"A guide to systematic reviews and meta-analyses in the field of epilepsy","authors":"Nathan A. Shlobin ,&nbsp;Michael Kinney ,&nbsp;Francesco Brigo","doi":"10.1016/j.yebeh.2025.110733","DOIUrl":"10.1016/j.yebeh.2025.110733","url":null,"abstract":"<div><div>Systematic reviews and meta-analyses (SRMAs) are increasingly used in epilepsy research to rigorously address clinical questions and inform patient care. Consequently, the ability to conduct and interpret SRMAs is essential for professionals in this field. This educational article offers a step-by-step guide to performing SRMAs, outlining eight key stages: formulating a research question, developing and publishing a protocol, conducting a comprehensive literature search, selecting studies, extracting data, assessing study quality, synthesizing results (qualitatively or quantitatively via meta-analysis), preparing and disseminating a final report. We also provide practical guidance on interpreting SRMAs, highlighting the importance of evaluating the robustness of findings and their clinical relevance. By equipping epilepsy professionals with these skills, this guide supports the advancement of evidence-based practice and the improvement of patient outcomes.</div></div>","PeriodicalId":11847,"journal":{"name":"Epilepsy & Behavior","volume":"172 ","pages":"Article 110733"},"PeriodicalIF":2.3,"publicationDate":"2025-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145216530","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The efficacy of switching intravenous to oral brivaracetam following status epilepticus: A real-world, multicenter Sicilian study 癫痫持续状态后静脉转口服布伐西坦的疗效:一项真实世界、多中心西西里研究
IF 2.3 3区 医学
Epilepsy & Behavior Pub Date : 2025-10-02 DOI: 10.1016/j.yebeh.2025.110744
C. Martellino , G. Salafica , G. Tripepi , A. Vinaccia , G. Atanasio , Diana Tilenni , F. Lamanna , O. Pardeo , M. Panebianco , L. Urso , G. Maira , P. Laisa , S. Zappulla , M. Gammino , D.Lo Coco , L. Agrò , R. Avarello , L. Zummo , A. Laganà , A. Labate
{"title":"The efficacy of switching intravenous to oral brivaracetam following status epilepticus: A real-world, multicenter Sicilian study","authors":"C. Martellino ,&nbsp;G. Salafica ,&nbsp;G. Tripepi ,&nbsp;A. Vinaccia ,&nbsp;G. Atanasio ,&nbsp;Diana Tilenni ,&nbsp;F. Lamanna ,&nbsp;O. Pardeo ,&nbsp;M. Panebianco ,&nbsp;L. Urso ,&nbsp;G. Maira ,&nbsp;P. Laisa ,&nbsp;S. Zappulla ,&nbsp;M. Gammino ,&nbsp;D.Lo Coco ,&nbsp;L. Agrò ,&nbsp;R. Avarello ,&nbsp;L. Zummo ,&nbsp;A. Laganà ,&nbsp;A. Labate","doi":"10.1016/j.yebeh.2025.110744","DOIUrl":"10.1016/j.yebeh.2025.110744","url":null,"abstract":"<div><h3>Background</h3><div>Brivaracetam (BRV) is a third-generation antiseizure medication (ASM) that acts as a high-affinity ligand for synaptic vesicle protein 2A (SV2A), sharing a similar mechanism of action with levetiracetam (LEV). Nevertheless, BRV exhibits higher binding affinity and selectivity for SV2A and a more favorable safety profile. We aim to study the efficacy of switching intravenous to oral BRV following status epilepticus (SE) and cluster seizures.</div></div><div><h3>Methods</h3><div>We conducted a multicenter, retrospective, observational study performed at seven Sicilian epilepsy centers in the context of real-world clinical practice. Recruited patients received intravenous BRV as a second-line treatment for SE and subsequently switched to oral administration. Outcome measures were responder rate (≥ 50 % seizure reduction), sustained seizure freedom and the occurrence of adverse events. were defined as the occurrence, number, and type of adverse events (AEs).</div></div><div><h3>Results</h3><div>75 patients were included in the study whereas seven were excluded because of death before six months of follow-up and five were because lost at follow-up. Sixty-two patients (mean age 69.63 ± 12.99) were included in the present analyses. The mean dosage of BRV was 165 mg (SD 50,04) mg/day at 8.7 months. The retention rate of BRV was 93.7 %. At follow-up, 30 (47.6 %) patients showed sustained seizure freedom, in 22 (34.9 %) seizure frequency decreased ≥ 50 % and 10 (16,1%) experienced a clinical worsening. Adverse events (AEs) were observed in two out of 62 participants (3.2 %). We didn’t find any correlation between sex, age, dosage of BRV and the sustained seizure freedom or the reduction in the number of seizures ≥ 50 % (p = 0.57; p = 0.26; p = 0.57, respectively). Patients with vascular aetiology had a likelihood of resolution or a reduction ≥ 50 % approximately three times higher (odds ratio 3.13<!--> <!-->(IC 95 %: 1.01–9.77), p = 0.05) than others.</div></div><div><h3>Conclusions</h3><div>The switch of BRV from intravenous to oral administration has demonstrated a good effectiveness and safety profile in long-term treatment of epilepsy following a prior SE particularly in patients with vascular diseases.</div></div>","PeriodicalId":11847,"journal":{"name":"Epilepsy & Behavior","volume":"172 ","pages":"Article 110744"},"PeriodicalIF":2.3,"publicationDate":"2025-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145216598","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The association between DTI-based thalamocortical structural connection and the efficacy of vagus nerve stimulation in patients with drug-resistant epilepsy 基于dti的丘脑皮质结构连接与耐药癫痫迷走神经刺激疗效的关系
IF 2.3 3区 医学
Epilepsy & Behavior Pub Date : 2025-10-02 DOI: 10.1016/j.yebeh.2025.110734
Zi-Ao Xu, Bohang Liu, Ming Shan, Xue-Fei Ji, Lei Ye, Hong-Wei Cheng
{"title":"The association between DTI-based thalamocortical structural connection and the efficacy of vagus nerve stimulation in patients with drug-resistant epilepsy","authors":"Zi-Ao Xu,&nbsp;Bohang Liu,&nbsp;Ming Shan,&nbsp;Xue-Fei Ji,&nbsp;Lei Ye,&nbsp;Hong-Wei Cheng","doi":"10.1016/j.yebeh.2025.110734","DOIUrl":"10.1016/j.yebeh.2025.110734","url":null,"abstract":"<div><h3>Aim</h3><div>Vagus nerve stimulation (VNS) is an important treatment option for patients with drug-resistant epilepsy (DRE). However, there is a lack of effective indicators to predict the efficacy of VNS. We aimed to investigate the correlation between thalamocortical structural connection and efficacy of VNS treatment.</div></div><div><h3>Method</h3><div>A total of 31 DRE patients and 30 healthy individuals were recruited. All participants received cranial DTI scans. The thalamic subareas were segmented as the region of interest (ROI) by probabilistic tractography. Five pathways of the structural connection between thalamus ROI and corresponding cerebral cortex ROI were analyzed respectively, including thalamus-prefrontal cortex (thalamus-PFC), thalamus-motor and premotor cortex (thalamus-MC), thalamus-somatosensory cortex (thalamus-SC), thalamus- parietal and occipital cortex (POC) and thalamus-temporal cortex (thalamus-TC). The integrity of the thalamocortical structural connection was evaluated by 4 indices, including fractional anisotropy (FA), mean diffusivity (MD), radial diffusivity (RD) and axial diffusivity (AD). The correlation between thalamocortical structural connections and the response to VNS treatment were then analyzed.</div></div><div><h3>Results</h3><div>DRE patients exhibited significantly lower FA values in the thalamus-PFC, thalamus-MC, thalamus-SC, thalamus-POC, and thalamus-TC regions compared to controls, with increased MD and RD values in the thalamus-PFC, thalamus-SC and thalamus-MC regions. Within the DRE group, the FA values in the thalamus-PFC and thalamus-TC regions were significantly higher, while the RD values were significantly lower compared to the other three regions. DRE patients who had better response to VNS treatment had higher FA values in the thalamus-PFC and thalamus-TC regions.</div></div><div><h3>Conclusion</h3><div>there are damages of neural fiber integrity within the thalamo-cortical connection pathway in DRE patients, which is associated with demyelinating lesions. Those patients with relatively intact thalamo-cortical connections tend to achieve better response to VNS treatment.</div></div>","PeriodicalId":11847,"journal":{"name":"Epilepsy & Behavior","volume":"172 ","pages":"Article 110734"},"PeriodicalIF":2.3,"publicationDate":"2025-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145216600","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evidence of language network reorganization and compromised cognitive functioning in pediatric patients with focal refractory epilepsy 局灶性难治性癫痫患儿的语言网络重组和认知功能受损的证据
IF 2.3 3区 医学
Epilepsy & Behavior Pub Date : 2025-10-02 DOI: 10.1016/j.yebeh.2025.110739
Dana Martino , Alena Hornak , Elmira Hassanzadeh , Masoud Hassanzadeh , Jeffrey Bolton , Phillip L. Pearl , Simon Warfield , Alyssa Ailion
{"title":"Evidence of language network reorganization and compromised cognitive functioning in pediatric patients with focal refractory epilepsy","authors":"Dana Martino ,&nbsp;Alena Hornak ,&nbsp;Elmira Hassanzadeh ,&nbsp;Masoud Hassanzadeh ,&nbsp;Jeffrey Bolton ,&nbsp;Phillip L. Pearl ,&nbsp;Simon Warfield ,&nbsp;Alyssa Ailion","doi":"10.1016/j.yebeh.2025.110739","DOIUrl":"10.1016/j.yebeh.2025.110739","url":null,"abstract":"<div><h3>Objective</h3><div>Patients with focal refractory frontal or temporal lobe epilepsy are at risk for overlap between the epileptogenic zone and eloquent language cortex, potentially resulting in language reorganization or atypical language representation. While such reorganization may indicate functional resilience, it may reflect compromised neural networks and poorer language outcomes. We hypothesized that patients with left frontal or temporal seizure onset zones would more often demonstrate atypical language dominance and lower cognitive and language compared to patients with right seizure onset zones.</div></div><div><h3>Methods</h3><div>We retrospectively reviewed 26 patients with frontal (n = 12)<!--> <!-->or temporal (n = 14) lobe epilepsy who underwent Phase I Surgical Evaluation, including structural and functional MRI and neuropsychological evaluation. FMRI using Auditory Description Decision Task provided language laterality indices. Participants were grouped as <strong>reorganized</strong> (Left seizure onset zones, Right/Bilateral LI; n = 8), <strong>not reorganized</strong> (Left seizure onset zones, Left LI; n = 10), and <strong>right seizure onset zones</strong> (n = 8). Neuropsychological assessments included Wechsler IQ tests, Boston Naming Test and Delis-Kaplan Executive Function System.</div></div><div><h3>Results</h3><div>Patients with <strong>left seizure onset zones</strong> had earlier seizure onset and longer epilepsy duration than the <strong>right seizure onset zones</strong> group. The <strong>reorganized</strong> group showed lower Perceptual/Fluid Reasoning Index scores compared to other groups.</div></div><div><h3>Significance</h3><div>This study is one of the few to investigate the combination of neuropsychological measures and fMRI language lateralization and found that fMRI language reorganization was associated with lower cognitive and perceptual/fluid reasoning. Language reorganization may indicate compromised neural networks or developmental persistence.</div></div>","PeriodicalId":11847,"journal":{"name":"Epilepsy & Behavior","volume":"172 ","pages":"Article 110739"},"PeriodicalIF":2.3,"publicationDate":"2025-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145216599","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Implementation of clinic-based data capture in a real-world epilepsy clinic 在现实世界癫痫诊所实现基于临床的数据捕获
IF 2.3 3区 医学
Epilepsy & Behavior Pub Date : 2025-10-02 DOI: 10.1016/j.yebeh.2025.110730
Gabriel Martz , Isshori Gurung , Ya-Huei Li
{"title":"Implementation of clinic-based data capture in a real-world epilepsy clinic","authors":"Gabriel Martz ,&nbsp;Isshori Gurung ,&nbsp;Ya-Huei Li","doi":"10.1016/j.yebeh.2025.110730","DOIUrl":"10.1016/j.yebeh.2025.110730","url":null,"abstract":"<div><div>Capturing structured clinical data during routine care remains an elusive but potentially high-impact goal. Learning Health Systems (LHS) are intended to capture data and provide evidence-based guidance, improving the care clinicians provide. Our epilepsy center implemented software to enable patient survey delivery and discrete data entry by clinicians during clinic visits. Here we evaluate the initial 18 months of this process. There were 2779 visits by 1664 patients seeing 12 clinicians. Manual entry of any data by clinicians occurred in 59.5 % of visits, and entry of all data domains occurred in 48.9 %, dominated by 3 clinicians who completed 74 % of these visits. Clinician manual entry rate was slightly higher among White, non-Hispanic and male patient visits, those with Medicaid or Self Pay as primary insurance, and among follow up visits (vs new patient). Patient surveys were all completed in 16.2 % and at least one survey in 54.7 % of visits. Higher rate of patient survey completion was associated with English speakers, in person visits (vs virtual), new patient visits, and private insurance. There was no association of survey completion with race, ethnicity or diagnosis. Overall, clinical data capture is achievable when there is strong clinician engagement and optimization of clinic workflows to enable survey completion. Care should be taken to ensure implementation captures representative data and avoids systematically marginalizing people facing social barriers to healthcare.</div></div>","PeriodicalId":11847,"journal":{"name":"Epilepsy & Behavior","volume":"172 ","pages":"Article 110730"},"PeriodicalIF":2.3,"publicationDate":"2025-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145216601","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Immediate-use rescue medication and the epilepsy monitoring unit: experiences from an expert panel. 立即使用抢救药物和癫痫监测单位:专家小组的经验。
IF 2.3 3区 医学
Epilepsy & Behavior Pub Date : 2025-10-01 Epub Date: 2025-08-07 DOI: 10.1016/j.yebeh.2025.110644
Evelyn K Shih, Brin E Freund, Michael R Sperling, Danielle A Becker, Proleta Datta, Sandra Dewar, Edward Faught, Tracy Glauser, R Edward Hogan, Randa Jarrar, Andres M Kanner, David King-Stephens, Rebecca E Matthews, Patricia Penovich, M Scott Perry, Eric B Segal, Joseph Sirven, John M Stern, James W Wheless, Enrique Carrazana, Adrian L Rabinowicz, William O Tatum
{"title":"Immediate-use rescue medication and the epilepsy monitoring unit: experiences from an expert panel.","authors":"Evelyn K Shih, Brin E Freund, Michael R Sperling, Danielle A Becker, Proleta Datta, Sandra Dewar, Edward Faught, Tracy Glauser, R Edward Hogan, Randa Jarrar, Andres M Kanner, David King-Stephens, Rebecca E Matthews, Patricia Penovich, M Scott Perry, Eric B Segal, Joseph Sirven, John M Stern, James W Wheless, Enrique Carrazana, Adrian L Rabinowicz, William O Tatum","doi":"10.1016/j.yebeh.2025.110644","DOIUrl":"10.1016/j.yebeh.2025.110644","url":null,"abstract":"<p><strong>Background: </strong>People with epilepsy (PWE) may experience seizure clusters, broadly defined as ≥2 seizures that occur in close proximity. In epilepsy monitoring units (EMUs), seizure clusters can spontaneously occur during long-term videoelectroencephalogram monitoring (LTVEM) or as a result of antiseizure medication dose adjustments. In this survey, we examined the experiences and practices of expert clinicians with seizure clusters in EMUs.</p><p><strong>Methods: </strong>A 55-item survey was sent to members of an Epilepsy Education Council who are epilepsy experts. Items described experiences, treatment practices, and negative outcomes with seizure clusters in EMUs.</p><p><strong>Results: </strong>Of the 15 experts (aged 43-77 y), 14 are physicians and 1 is an advanced practice provider; 14 work at level 4 epilepsy centers. The definition of seizure cluster varied across experts, from 2 seizures in 1 hour to 3 seizures over 24 hours. Twelve experts prescribe immediate-use rescue medication (RM) during EMU stay, usually a benzodiazepine. An intranasal route is preferred by 11 if intravenous access is unavailable. Nine experts have had a presurgical evaluation compromised owing to seizure clusters during LTVEM, and 12 have cared for PWE who required transfer to a higher-level care (eg, intensive care unit) owing to seizure clusters. Thirteen experts indicated they would follow expert consensus recommendations for immediate-use RMs in the EMU if available.</p><p><strong>Conclusions: </strong>In the EMU, seizure clusters may compromise presurgical evaluations and require higher levels of care. Consensus recommendations are needed to guide patient-specific treatment practices before, during, and after EMU admission.</p>","PeriodicalId":11847,"journal":{"name":"Epilepsy & Behavior","volume":"171 ","pages":"110644"},"PeriodicalIF":2.3,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144803879","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Musical neurostimulation improves cognitive function in children with epilepsy and causes electroencephalogram changes. 音乐神经刺激可改善癫痫患儿的认知功能并引起脑电图改变。
IF 2.3 3区 医学
Epilepsy & Behavior Pub Date : 2025-10-01 Epub Date: 2025-08-08 DOI: 10.1016/j.yebeh.2025.110647
Wei-Han Wang, Yung-Chia Chen, Rei-Cheng Yang, Mei-Wen Lee, Hin-Kiu Mok, Chen-Sen Ouyang, Yi-Hung Chiu, Rong-Ching Wu, Lung-Chang Lin
{"title":"Musical neurostimulation improves cognitive function in children with epilepsy and causes electroencephalogram changes.","authors":"Wei-Han Wang, Yung-Chia Chen, Rei-Cheng Yang, Mei-Wen Lee, Hin-Kiu Mok, Chen-Sen Ouyang, Yi-Hung Chiu, Rong-Ching Wu, Lung-Chang Lin","doi":"10.1016/j.yebeh.2025.110647","DOIUrl":"10.1016/j.yebeh.2025.110647","url":null,"abstract":"<p><strong>Purpose: </strong>Cognitive impairments are common in patients with epilepsy. Three musical pieces-Mozart's K. 448 first movement; Johann Sebastian Bach's Harpsichord Concerto No. 1 in D Minor, BWV 1052: I. Allegro; and Johann Christian Bach's Keyboard Concerto in E-flat Major, Op. 7-5: Allegro di Molto-were used as an intervention of musical neurostimulation in patients with epilepsy.</p><p><strong>Methods: </strong>A total of 34 children with epilepsy (13 boys, 21 girls) were involved. Each patient was randomly assigned to listen to one of the three musical pieces before bedtime every day for 6 months at home. An electroencephalogram (EEG), a neurocognitive test, and a Pediatric Quality of Life Inventory survey were conducted before and after the intervention.</p><p><strong>Results: </strong>The intervention significantly improved the patients' overall cognitive performance, including their memory, attention, processing speed, verbal fluency, and abstract thinking. However, no significant changes were found in their perceptual reasoning or executive function. In addition, the intervention had a positive effect on quality of life. EEG analysis revealed significantly increased alpha, beta, and gamma band power and significantly decreased theta and delta band power. It also revealed significantly increased EEG features of Hjorth complexity, Hjorth mobility, Higuchi fractal dimension, Lempel-Ziv complexity, Petrosian fractal dimension, and sample entropy and significantly decreased the EEG feature of detrended fluctuation analysis, particularly in the frontal regions.</p><p><strong>Conclusions: </strong>Listening to Mozart's K. 448, Johann Sebastian Bach's Allegro, and Johann Christian Bach's Allegro di Molto is a promising approach for improving the cognitive function of children with epilepsy.</p>","PeriodicalId":11847,"journal":{"name":"Epilepsy & Behavior","volume":"171 ","pages":"110647"},"PeriodicalIF":2.3,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144811959","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Response to “The landscape of uncertainty: living, healing and dying with epilepsy. Anthropological reflections” 对“不确定的景观:与癫痫共存、治愈和死亡”的回应。人类学反思”。
IF 2.3 3区 医学
Epilepsy & Behavior Pub Date : 2025-09-29 DOI: 10.1016/j.yebeh.2025.110679
Giancarlo Di Gennaro , Andrea Tomasini , Damiano Abeni , Angelo Labate , Carlo Di Bonaventura
{"title":"Response to “The landscape of uncertainty: living, healing and dying with epilepsy. Anthropological reflections”","authors":"Giancarlo Di Gennaro ,&nbsp;Andrea Tomasini ,&nbsp;Damiano Abeni ,&nbsp;Angelo Labate ,&nbsp;Carlo Di Bonaventura","doi":"10.1016/j.yebeh.2025.110679","DOIUrl":"10.1016/j.yebeh.2025.110679","url":null,"abstract":"","PeriodicalId":11847,"journal":{"name":"Epilepsy & Behavior","volume":"172 ","pages":"Article 110679"},"PeriodicalIF":2.3,"publicationDate":"2025-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145198742","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
EpilepTikTok: An inductive thematic analysis and quality assessment of #epilepsy content shared via a popular social media platform 癫痫tiktok:对热门社交媒体平台上分享的#癫痫内容进行归纳主题分析和质量评估。
IF 2.3 3区 医学
Epilepsy & Behavior Pub Date : 2025-09-29 DOI: 10.1016/j.yebeh.2025.110711
Hannah E. Snyder , Kyra Horsthuis , Kristal Cerga , David Callen
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