Luca Bertolaccini, Monica Casiraghi, Lorenzo Spaggiari
{"title":"Chronos, Kairos, and the environmental control against radon.","authors":"Luca Bertolaccini, Monica Casiraghi, Lorenzo Spaggiari","doi":"10.1097/CEJ.0000000000000857","DOIUrl":"10.1097/CEJ.0000000000000857","url":null,"abstract":"","PeriodicalId":11830,"journal":{"name":"European Journal of Cancer Prevention","volume":" ","pages":"241-242"},"PeriodicalIF":2.4,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138298747","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Impact of risk perception and disease cognition on the willingness to participate in screening for lung cancer in a high-risk population.","authors":"Feng Rong, Rui Shi, Lili Hu, Daoyue Wang, Xiazhi Lv, Yong Zhao","doi":"10.1097/CEJ.0000000000000843","DOIUrl":"10.1097/CEJ.0000000000000843","url":null,"abstract":"<p><strong>Objective: </strong>Risk perception and disease cognition may influence the efficiency of lung cancer screening by affecting the participation rate. There is still some uncertainty regarding the association between risk perception and disease cognition and how they affect participation in lung cancer screening. Therefore, we explored the influence of risk perception and disease cognition on the willingness to participate in screening among people at high risk of lung cancer.</p><p><strong>Methods: </strong>Subjects with high-risk factors for lung cancer were recruited in Lu'an City, Anhui Province, China. Questionnaires were used to determine their demographic characteristics, risk perception, disease cognition, and willingness to engage in screening.</p><p><strong>Results: </strong>Of the 1955 subjects with high risk factors for lung cancer, 1136 (58.12%) were willing to participate in lung cancer screening. Univariable and multivariable analyses showed that disease cognition ( adj OR = 2.012, 95% CI: 1.528-2.649, P = 0.000), cognitive risk ( adj OR = 7.661, 95% CI: 6.049-9.704, P = 0.000), and affective risk ( adj OR = 5.964, 95% CI: 4.552-7.815, P = 0.000) were significant factors in promoting screening participation. For those with moderate risk perception, improving disease cognition was a key approach to increase screening participation.</p><p><strong>Conclusion: </strong>This study elucidated the relationship between various factors and lung cancer screening participation and proposed a feasible route for the screening implementation, providing a theoretical basis to further improve the participation rate and efficiency of lung cancer screening.</p>","PeriodicalId":11830,"journal":{"name":"European Journal of Cancer Prevention","volume":" ","pages":"141-151"},"PeriodicalIF":2.4,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41119772","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Eliane Kellen, Zoi Meers, Lore Pil, Mathijs C Goossens
{"title":"Impact of altering the invitation package on screening participation among never-screeners in the Flemish population-based cancer screening programs.","authors":"Eliane Kellen, Zoi Meers, Lore Pil, Mathijs C Goossens","doi":"10.1097/CEJ.0000000000000848","DOIUrl":"10.1097/CEJ.0000000000000848","url":null,"abstract":"<p><strong>Background: </strong>The total coverage of both the Flemish breast cancer and cervical screening program remain suboptimal, with approximately 63% for both. Of all the women invited to the breast cancer screening program, 14.1% never underwent any type of breast cancer screening (any type of mammogram, ultrasound, or clinical breast examination). For the cervical cancer screening, this proportion of 'never-screeners' is 12.1%. We conducted two randomized controlled trials to assess whether various communication and presentation styles in the invitation package, were effective at motivating women who had never participated to attend.</p><p><strong>Methods: </strong>The study population was limited to never-screeners (women who had never participated in the screening program). The RCT embedded in the breast cancer screening consisted of seven intervention arms and one control arm (all of them included a fixed appointment by letter). The RCT embedded in the cervical cancer screening consisted of three intervention arms and two control arms. In both RCTs, several content and style adaptations were made to the invitation letter, information leaflet, and envelope.</p><p><strong>Results: </strong>None of the intervention arms in either the breast cancer screening or the cervical cancer screening had a statistically significant impact on the participation rate compared to 'usual care' (the regular invitation package used in the screening program).</p><p><strong>Conclusion: </strong>Sending adapted invitation packages to never-screeners, from the Flemish breast and cervical cancer screening program, does not seem to be effective in increasing the proportion of women screened. Innovative methods are needed to motivate never-screeners to be screened.</p>","PeriodicalId":11830,"journal":{"name":"European Journal of Cancer Prevention","volume":" ","pages":"181-184"},"PeriodicalIF":2.4,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139377391","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Reinvestigating the Perceptions of Annual Skin Cancer Screening Scale: a suitable measure for older adults.","authors":"Matt C Howard","doi":"10.1097/CEJ.0000000000000846","DOIUrl":"10.1097/CEJ.0000000000000846","url":null,"abstract":"<p><strong>Objectives: </strong>The Perceptions of Annual Skin Cancer Screening Scale (PASCSS) explains significant variance in whether people undergo annual clinical skin cancer screening beyond other relevant predictors. When developing the PASCSS, the author only tested its psychometric properties and validity with participants representative of the general USA population, despite the particular relevance of annual clinical skin cancer screenings to at-risk populations, namely, older adults. We reanalyze the PASCSS using a sample of older adults.</p><p><strong>Methods: </strong>We conducted a three-wave survey study (n = 237) with each wave separated by one week. Demographic information was recorded at Time 1. The PASCSS was administered at Time 2. Outcomes were measured at Time 3.</p><p><strong>Results: </strong>The model fit of our confirmatory factor analysis met or closely approached traditional cutoffs, and each item loaded very strongly onto its respective latent factor. These PASCSS's dimensions together explained an additional 38% of variance in dermatologist screening and 37% of variance in any medical professional screening beyond our control variables (both P < 0.01). The dimension of Unknowledgeable was statistically significant in predicting dermatologist screening ( P = 0.03), whereas the three dimensions of Forget, Recommended, and Unknowledgeable were statistically significant in predicting any medical professional screening (all P < 0.05).</p><p><strong>Conclusion: </strong>Our results supported the psychometric properties and validity of the PASCSS, and we showed that the dimensions significantly relate to whether participants received a clinical skin cancer screening in the past year. The current investigation supports that the PASCSS is appropriate to administer to older adults.</p>","PeriodicalId":11830,"journal":{"name":"European Journal of Cancer Prevention","volume":" ","pages":"177-180"},"PeriodicalIF":2.4,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41131635","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Primary tumor resection improves prognosis of unresectable carcinomas of the transverse colon including flexures with pulmonary metastasis: a cohort study.","authors":"Huixia Zhao, Guangze Song, Ruliang Wang, Na Guan, Chao Yun, Jingwen Yang, Jin-Bao Ma, Hui Li, Wenhua Xiao, Liang Peng","doi":"10.1097/CEJ.0000000000000841","DOIUrl":"10.1097/CEJ.0000000000000841","url":null,"abstract":"<p><strong>Purpose: </strong>Studies of unresectable colorectal cancer pulmonary metastasis (CRPM) have rarely analyzed patient prognosis from the perspective of colonic subsites. This study aimed to evaluate the effects of primary tumor resection (PTR) on the prognosis of patients with unresectable pulmonary metastases of transverse colon cancer pulmonary metastasis (UTCPM), hepatic flexure cancer pulmonary metastasis (UHFPM), and splenic flexure cancer pulmonary metastasis (USFPM).</p><p><strong>Methods: </strong>Patients were identified from the Surveillance, Epidemiology, and End Results database between 2000 and 2018. The Cox proportional hazards regression models were used to identify prognostic factors of overall survival (OS) and cause-specific survival (CSS). The Kaplan-Meier analyses and log-rank tests were conducted to assess the effectiveness of PTR on survival.</p><p><strong>Results: </strong>This study included 1294 patients: 419 with UHFPM, 636 with UTCPM, and 239 with USFPM. Survival analysis for OS and CSS in the PTR groups, showed that there were no statistical differences in the the UHFPM, UTCPM, and USFPM patients. There were statistical differences in the UHFPM, UTCPM, and USFPM patients for OS and CSS. Three non-PTR subgroups showed significant statistical differences for OS and CSS.</p><p><strong>Conclusion: </strong>We confirmed the different survival rates of patients with UTCPM, UHFPM, and USFPM and proved for the first time that PTR could provide survival benefits for patients with unresectable CRPM from the perspective of the colonic subsites of the transverse colon, hepatic flexure, and splenic flexure.</p>","PeriodicalId":11830,"journal":{"name":"European Journal of Cancer Prevention","volume":" ","pages":"95-104"},"PeriodicalIF":2.4,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10833197/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41195419","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Silvia Mignozzi, Claudia Santucci, Matteo Malvezzi, Fabio Levi, Carlo La Vecchia, Eva Negri
{"title":"Global trends in anal cancer incidence and mortality.","authors":"Silvia Mignozzi, Claudia Santucci, Matteo Malvezzi, Fabio Levi, Carlo La Vecchia, Eva Negri","doi":"10.1097/CEJ.0000000000000842","DOIUrl":"10.1097/CEJ.0000000000000842","url":null,"abstract":"<p><strong>Objective: </strong>Anal cancer is a rare disease, affecting more frequently women than men, mainly related to human papillomavirus infection (HPV). Rising incidence and mortality have been reported over the past four decades in different countries.</p><p><strong>Methods: </strong>To provide an up-to-date overview of recent trends in mortality from anal cancer, we analysed death certification data provided by the WHO in selected countries worldwide over the period from 1994 to 2020. We also analysed incidence derived from Cancer Incidence in Five Continents from 1990 to 2012 for all histologies as well as for anal squamous cell carcinoma (SCC).</p><p><strong>Results: </strong>The highest age-standardised mortality rates around 2020 were registered in Central and Eastern Europe, such as Slovakia (0.9/100 000 men and 0.40/100 000 women), in the UK (0.24/100 000 men and 0.35/100 000 women), and Denmark (0.33/100 000 for both sexes), while the lowest ones were in the Philippines, Mexico, and Japan, with rates below 0.10/100 000 in both sexes. Upwards trends in mortality were reported in most countries for both sexes. Similarly, incidence patterns were upward or stable in most countries considered for both sexes. In 2008-2012, Germany showed the highest incidence rates (1.65/100 000 men and 2.16/100 000 women).</p><p><strong>Conclusion: </strong>Attention towards vaccination against HPV, increased awareness of risk factors, mainly related to sexual behaviours and advancements in early diagnosis and management are required to control anal cancer incidence and mortality.</p>","PeriodicalId":11830,"journal":{"name":"European Journal of Cancer Prevention","volume":" ","pages":"77-86"},"PeriodicalIF":2.4,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10833181/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138477071","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Resilience and its related factors among women with breast cancer.","authors":"Hossein Ostadi-Sefidan, Farnaz Faroughi, Azita Fathnezhad-Kazemi","doi":"10.1097/CEJ.0000000000000839","DOIUrl":"10.1097/CEJ.0000000000000839","url":null,"abstract":"<p><strong>Objectives: </strong>Breast cancer is the most challenging disease, and the level of resilience in patients determines their ability to cope with the arising stress. There is relatively limited information on the resilience of patients in clinical settings. Our study aims were to evaluate the extent of resilience and identify factors that predict resilience in women with breast cancer.</p><p><strong>Patients and methods: </strong>A cross-sectional study was conducted with the participation of 218 women with breast cancer who were referred to the Oncology clinic in 2022. The participants completed three scales, namely the Conner-Davidson Resilience, Schneider's Life Expectancy, and the Multidimensional Scale of Perceived Social Support, along with sociodemographic information. Descriptive statistics, bivariate, and multiple linear regression were used to explore the predictors of resilience.</p><p><strong>Result: </strong>The mean (SD) scores for resilience, social support, and hope were 59.22 (17.25), 38.53 (6.19), and 59.37 (16.68), respectively. Based on analysis 50.8% of the variations in resilience could be explained by 6 variables including social support, hope, women's age, employment, and income status as well as the stage of illness (R 2adj = 0.508, P < 0.001). Employment status and disease stage did not show a significant relationship with resilience and social support was the factor with the highest impact on resilience (β = 0.516, P < 0.001).</p><p><strong>Conclusion: </strong>Our study showed social support, hope, age, and income level predict significant resilience in women with breast cancer. The findings emphasize the importance of fostering strong support networks, cultivating a hopeful mindset, embracing life's transitions, and addressing financial considerations in the pursuit of enhanced resilience.</p>","PeriodicalId":11830,"journal":{"name":"European Journal of Cancer Prevention","volume":" ","pages":"129-135"},"PeriodicalIF":2.4,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10215386","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Francesco Di Bello, Ernesto di Mauro, Giovanni Maria Fusco, Alfonso Falcone, Gabriele Pezone, Claudia Collà Ruvolo, Gianluigi Califano, Agostino Fraia, Francesco Passaro, Francesco Pepillo, Alessandro Ranieri, Pierluigi Alvino, Francesco Mastrangelo, Carmine Turco, Luigi Cirillo, Corrado Aniello Franzese, Roberto La Rocca, Massimiliano Creta, Nicola Longo, Luigi Napolitano
{"title":"A mobile health application for prostate cancer antigen dosage: is it time to say goodbye to classic screening methods?","authors":"Francesco Di Bello, Ernesto di Mauro, Giovanni Maria Fusco, Alfonso Falcone, Gabriele Pezone, Claudia Collà Ruvolo, Gianluigi Califano, Agostino Fraia, Francesco Passaro, Francesco Pepillo, Alessandro Ranieri, Pierluigi Alvino, Francesco Mastrangelo, Carmine Turco, Luigi Cirillo, Corrado Aniello Franzese, Roberto La Rocca, Massimiliano Creta, Nicola Longo, Luigi Napolitano","doi":"10.1097/CEJ.0000000000000845","DOIUrl":"10.1097/CEJ.0000000000000845","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the quality of apps for prostate cancer antigen (PSA) dosage, available for downloading on the iOS and Android platforms, discussing the potential role of mobile health applications (MHAs) in update the screening protocol.</p><p><strong>Methods: </strong>An observational cross-sectional descriptive study of all smartphone apps for PSA dosage was performed through the most used platforms (iOS and Android). On 10 February 2023, a total of 457 apps were found according to the search criteria. Mobile Application Rating Scale (MARS) was adopted to assess apps' quality. Then, MARS items were analyzed through descriptive statistics and bivariate correlations between study variables with Pearson's coefficient.</p><p><strong>Results: </strong>Of all samples, 24 MHAs were included in the final analysis: 12% (n = 3) from the iTunes App Store and 88% (n = 21) from the Google Play Store. According to the MARS quality assessment, the mean values 2.61, 2.94, 3.11, 2.97, 2.94, and 2.63 were measured for the engagement, functionality, aesthetics, information, overall mean score, and subjective quality, respectively.</p><p><strong>Conclusion: </strong>The MHAs for PSA were under the acceptability threshold and future improvements are required. Moreover, MHAs appropriately developed could play an active role in PSA screening campaign and adherence of follow-up regimens. Finally, the virtual instrument could both reduce the social divide of access to care for patients in rural areas and improve PCA detection, speeding up the active treatment.</p>","PeriodicalId":11830,"journal":{"name":"European Journal of Cancer Prevention","volume":" ","pages":"87-94"},"PeriodicalIF":2.4,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138487046","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jun-Peng Lin, Xiao-Feng Chen, Hang Zhou, Feng-Nian Zhuang, Hao He, Wei-Jie Chen, Feng Wang, Shuo-Yan Liu
{"title":"The association between histological subtypes and lymph node metastasis and prognosis in early esophageal cancer: a population-based study.","authors":"Jun-Peng Lin, Xiao-Feng Chen, Hang Zhou, Feng-Nian Zhuang, Hao He, Wei-Jie Chen, Feng Wang, Shuo-Yan Liu","doi":"10.1097/CEJ.0000000000000847","DOIUrl":"10.1097/CEJ.0000000000000847","url":null,"abstract":"<p><strong>Background: </strong>There is still a lack of high-level clinical evidence and uniform conclusions on whether there are differences in lymph node metastasis (LNM) and prognosis between early esophageal adenocarcinoma (EAC) and squamous cell carcinoma (ESCC).</p><p><strong>Methods: </strong>Patients with surgically resected, histologically diagnosed, pT1 EAC or ESCC in the Surveillance, Epidemiology and End Results registries database from 2004 to 2015 were included. Multivariable logistic regression, Cox regression, multivariate competing risk model, and propensity score matching were used to analyze association the histology and LNM or prognosis.</p><p><strong>Results: </strong>A total of 570 early esophageal cancer patients were included. The LNM rates were 13.8% and 15.1% for EAC and ESCC ( P = 0.757), respectively. Multivariate logistic regression analysis showed no significant association between histological type and LNM (odds ratio [OR], 1.209; 95% CI, 0.538-2.715; P = 0.646). Moreover, the prognosis of early EAC and ESCC was shown to be comparable in both multivariate Cox regression (hazard ratio [HR], 1.483; 95% CI, 0.699-3.150; P = 0.305) and the multivariate competing risk model (subdistribution HR, 1.451; 95% CI, 0.628-3.354; P = 0.383). After propensity score matching, there were no significant differences between early EAC and ESCC in terms of LNM (10.6% vs.18.2%, P = 0.215), 5-year CSS (89.8% [95% CI, 81.0%-98.6%] vs. 79.1% [95% CI, 67.9%-90.3%], P = 0.102) and 5-year cumulative incidence of CSS (10.2% [95% CI, 1.4%-19.0%] vs. 79.1% [95% CI, 9.7%-32.1%], P = 0.124).</p><p><strong>Conclusion: </strong>The risk of LNM and prognosis of early ESCC and EAC are comparable, so the treatment choice for early esophageal cancer does not depend on the histologic type.</p>","PeriodicalId":11830,"journal":{"name":"European Journal of Cancer Prevention","volume":" ","pages":"152-160"},"PeriodicalIF":2.4,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138290702","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Spatial mapping of colorectal cancer screening uptake and associated factors.","authors":"Getachew A Dagne","doi":"10.1097/CEJ.0000000000000840","DOIUrl":"10.1097/CEJ.0000000000000840","url":null,"abstract":"<p><strong>Objective: </strong>Over the past decades, it has been understood that the availability of screening tests has contributed to a steady decline in incidence of colorectal cancer (CRC). However, it is also seen that there is a geographic disparity in the use of such tests across small areas. The aim of this study is to examine small-area level barrier factors that may impact CRC screening uptake and to delineate coldspot (low uptake of screening) counties in Florida.</p><p><strong>Methods: </strong>Data on the percentages of county-level CRC screening uptakes in 2016 and county-level barrier factors for screening were obtained from the Florida Department of Health, Division of Public Health Statistics & Performance Management. Bayesian spatial beta models were used to produce posterior probability of deceedance to identify coldspots for CRC screening rates.</p><p><strong>Results: </strong>Unadjusted screening rates using sigmoidoscopy or colonoscopy test ranged from 56.8 to 85%. Bayesian spatial beta models were fitted to the proportion data. At an ecological level, we found that an increasing rate of CRC screening uptake for either of the test types (colon/rectum exam, stool-based test) was strongly associated with a higher health insurance coverage, and lower percentage of population that speak English less than very well (immigration) at county level. Eleven coldspot counties out of 67 total were also identified.</p><p><strong>Conclusion: </strong>This study suggests that health insurance disparities in the use of CRC screening tests are an important factor that may need more attention for resource allocation and health policy targeting small areas with low uptake of screening.</p>","PeriodicalId":11830,"journal":{"name":"European Journal of Cancer Prevention","volume":" ","pages":"161-167"},"PeriodicalIF":2.4,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10573052","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}