European Journal of Cancer Prevention最新文献_第8页

The global, regional, and national disease burden and risk factors of male breast cancer from 1990 to 2021: an analysis of the Global Burden of Disease Study. 1990年至2021年全球、区域和国家男性乳腺癌疾病负担和风险因素：对全球疾病负担研究的分析

IF 2.1 4区医学

European Journal of Cancer Prevention Pub Date : 2025-02-14 DOI: 10.1097/CEJ.0000000000000952

Jia-Yan Qu, Jing-Bo Lu, Hui-Jun Sun, Cai-Ping Meng, Li-Yuan Rong

{"title":"The global, regional, and national disease burden and risk factors of male breast cancer from 1990 to 2021: an analysis of the Global Burden of Disease Study.","authors":"Jia-Yan Qu, Jing-Bo Lu, Hui-Jun Sun, Cai-Ping Meng, Li-Yuan Rong","doi":"10.1097/CEJ.0000000000000952","DOIUrl":"https://doi.org/10.1097/CEJ.0000000000000952","url":null,"abstract":"Male breast cancer (MBC) contributes to approximately 1% of total breast cancer diagnoses, with rapidly rising incidence and mortality rates worldwide. Since most breast cancer research has focused on women, this study intended to report the incidence, mortality, and disability-adjusted life years (DALYs) of MBC to aid in its control and prevention. The data on the incidence, DALYs, deaths, and age-standardized rates of MBC between 1990 and 2021 in different countries and territories were sourced from the Global Burden of Disease (GBD) 2021 study. In 1990 and 2021, Eastern Sub-Saharan Africa had the highest incidence, DALYs, and mortality rates. Countries in the middle socio-demographic index quintile showed the fastest growth in age-standardized incidence rate, ASDR, and ASMR. From 1990 to 2021, the incidence, mortality rate, and DALYs of MBC increased worldwide. Alcohol use, dietary risks, and tobacco use were risk factors for ASMR, with dietary risks ranking first in all GBD regions. The rise in the number of cases of breast cancer in men places substantial stress on humans. Hence, policymakers should establish effective interventions and strategies for patients with MBC in accordance with the local situation.","PeriodicalId":11830,"journal":{"name":"European Journal of Cancer Prevention","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143406436","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

High utilization of colonoscopy and fecal occult blood testing for screening or diagnostic purposes in Germany: a longitudinal analysis. 在德国，结肠镜检查和粪便潜血检查用于筛查或诊断目的的高利用率：一项纵向分析。

IF 2.1 4区医学

European Journal of Cancer Prevention Pub Date : 2025-02-10 DOI: 10.1097/CEJ.0000000000000956

Michel Hornschuch, Sarina Schwarz, Ulrike Haug

{"title":"High utilization of colonoscopy and fecal occult blood testing for screening or diagnostic purposes in Germany: a longitudinal analysis.","authors":"Michel Hornschuch, Sarina Schwarz, Ulrike Haug","doi":"10.1097/CEJ.0000000000000956","DOIUrl":"https://doi.org/10.1097/CEJ.0000000000000956","url":null,"abstract":"It is often reported that participation in the German colorectal cancer (CRC) screening program is low. However, it must be considered that fecal occult blood testing (FOBT) and colonoscopy are offered in parallel and both are also used for diagnostic purposes. We aimed to quantify and characterize the uptake of these colorectal examinations in Germany. Using the claims database German Pharmacoepidemiological Research Database (~20% of the German population), we included persons aged 50 in 2011 in cohort 1 (cohort 2: age 55) and assessed whether they utilized FOBT or colonoscopy for screening or diagnostic purposes until age 59 (cohort 2: age 64). We have stratified the analyses, i.e. by gender and educational level. Among 185 949 50-year olds, 80% of women and 63% of men had ≥1 colorectal examination (i.e. FOBT or colonoscopy) until age 59; 25% of women and 31% of men had ≥1 colonoscopy (among those, 76 and 62% had a screening colonoscopy). In women with lower vs higher education, 79 vs 82% had any colorectal examination; in men, these proportions were 60 vs 67%. Among 156 258 55-year olds, 78% of women and 69% of men had ≥1 colorectal examination until age 64. Our study demonstrates a high utilization of colorectal examinations in Germany. It also illustrates the value of health claims data to monitor CRC screening in Germany due to their longitudinal character and because they include information on screening, on examinations done for diagnostic reasons as well as information suitable to characterize users and nonusers.","PeriodicalId":11830,"journal":{"name":"European Journal of Cancer Prevention","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143390553","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The global, regional, and national burden of colorectal cancer attributable to smoking from 1990 to 2021: a population-based study. 1990年至2021年吸烟导致的全球、区域和国家结直肠癌负担：一项基于人群的研究

IF 2.1 4区医学

European Journal of Cancer Prevention Pub Date : 2025-01-22 DOI: 10.1097/CEJ.0000000000000957

Shuai Wang, Tao Zhang, Dongming Li, Xueyuan Cao

{"title":"The global, regional, and national burden of colorectal cancer attributable to smoking from 1990 to 2021: a population-based study.","authors":"Shuai Wang, Tao Zhang, Dongming Li, Xueyuan Cao","doi":"10.1097/CEJ.0000000000000957","DOIUrl":"https://doi.org/10.1097/CEJ.0000000000000957","url":null,"abstract":"Colorectal cancer (CRC) is the third leading cause of cancer-related deaths worldwide, with smoking being a significant risk factor. Understanding the temporal and spatial patterns of the CRC burden attributable to smoking is crucial for global public health strategies. Data from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2021 were used to calculate the number of deaths, disability-adjusted life years (DALYs), age-standardized mortality rate (ASMR) per 100 000 population, and age-standardized disability-adjusted life year rate (ASDR). The average annual percentage change (AAPC) was calculated from 1990 to 2021 to analyze disease burden trends. Frontier analysis was conducted to assess efficiency, and predictions were made for the next decade. In 2021, the global death toll and DALYs attributable to smoking were 47 613 and 1 235 667, respectively. From 1990 to 2021, the absolute number of deaths and DALYs increased, while ASMR (AAPC: -1.20) and ASDR (AAPC: -1.22) showed a significant decline. The disease burden was notably higher in males than females. Analysis by the Social Development Index revealed that more developed regions had a higher burden than less developed areas. China ranked first in the number of deaths and DALYs, while Greenland had the highest ASMR and ASDR. From 1990 to 2021, the age-standardized burden of CRC attributable to smoking decreased globally. However, the absolute burden remains a significant public health challenge, requiring sustained and targeted interventions.","PeriodicalId":11830,"journal":{"name":"European Journal of Cancer Prevention","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143002382","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Development of a prediction model based on Hemoglobin, Albumin, Lymphocyte count, and Platelet-score for lymph node metastasis in rectal cancer. 建立基于血红蛋白、白蛋白、淋巴细胞计数和血小板评分的直肠癌淋巴结转移预测模型。

IF 2.1 4区医学

European Journal of Cancer Prevention Pub Date : 2025-01-22 DOI: 10.1097/CEJ.0000000000000954

Huanhui Liu, Qian Zou, Hanjing Zhang, Xiaojie Ma

{"title":"Development of a prediction model based on Hemoglobin, Albumin, Lymphocyte count, and Platelet-score for lymph node metastasis in rectal cancer.","authors":"Huanhui Liu, Qian Zou, Hanjing Zhang, Xiaojie Ma","doi":"10.1097/CEJ.0000000000000954","DOIUrl":"https://doi.org/10.1097/CEJ.0000000000000954","url":null,"abstract":"This study aimed to evaluate the ability of the preoperative Hemoglobin, Albumin, Lymphocyte count, and Platelet (HALP) score to predict lymph node metastasis (LNM) in patients with rectal cancer (RC) and improve prediction accuracy by incorporating clinical parameters. Data from 263 patients with RC were analyzed. The receiver operating characteristic (ROC) curve was used to determine the optimal cutoff value (OCV) for the HALP score in predicting LNM. Based on this cutoff value, patients were divided into two groups. A baseline analysis was conducted to identify independent factors linked to LNM. A support vector machine (SVM) prediction model was developed, and its performance was evaluated using ROC, calibration curves, decision curve analysis, and Kolmogorov-Smirnov curve. The OCV for HALP score was 45.979. Patients were then classified into a low HALP group (n = 182) and a high HALP group (n = 81). The analysis found 21 clinical factors significantly associated with LNM. Among them, the key risk factors included high inflammatory status, poor nutritional condition, and a low HALP score. The SVM model incorporated these factors and showed robust predictive performance, with area under the curve values of 0.897, 0.813, and 0.750 for the training, validation, and testing datasets, respectively. The HALP score was significantly associated with LNM in RC patients. A machine learning model integrating the HALP score and inflammatory markers may be an effective tool for predicting LNM in RC.","PeriodicalId":11830,"journal":{"name":"European Journal of Cancer Prevention","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143002368","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Correlation between skin cancer and therapy with anti-IL monoclonal antibodies in patients affected by moderate-to-severe psoriasis: an observational monocentric study. 中重度牛皮癣患者的皮肤癌与抗il单克隆抗体治疗的相关性：一项观察性单中心研究

IF 2.1 4区医学

European Journal of Cancer Prevention Pub Date : 2025-01-07 DOI: 10.1097/CEJ.0000000000000948

Flavia Manzo Margiotta, Cristian Fidanzi, Simone Pardossi, Alessandra Michelucci, Giammarco Granieri, Giorgia Salvia, Matteo Bevilacqua, Riccardo Morganti, Salvatore Panduri, Giovanni Bagnoni, Marco Romanelli, Agata Janowska, Valentina Dini

{"title":"Correlation between skin cancer and therapy with anti-IL monoclonal antibodies in patients affected by moderate-to-severe psoriasis: an observational monocentric study.","authors":"Flavia Manzo Margiotta, Cristian Fidanzi, Simone Pardossi, Alessandra Michelucci, Giammarco Granieri, Giorgia Salvia, Matteo Bevilacqua, Riccardo Morganti, Salvatore Panduri, Giovanni Bagnoni, Marco Romanelli, Agata Janowska, Valentina Dini","doi":"10.1097/CEJ.0000000000000948","DOIUrl":"https://doi.org/10.1097/CEJ.0000000000000948","url":null,"abstract":"Our study aimed to investigate the correlation between skin cancer and anti-interleukin (IL) therapy in patients with moderate-to-severe psoriasis. This was an observational monocentric study in which we enrolled a total of 235 patients in which 127 patients were affected by moderate-to-severe psoriasis and treated with anti-IL monoclonal antibodies (mAbs) for at least 6 months, whereas 108 patients affected by mild psoriasis were treated with topical therapies. Afterward, we performed a dermatologic visit to all the subjects, collecting anamnestic information including risk factors for skin cancer. We examined the skin lesions on their entire body by polarized and nonpolarized dermoscopy. A total of 21 suspicious lesions in the first group and 17 in the second one were removed and histologically analyzed. Twelve (9.4%) cancerous or precancerous lesions were found in the first group: seven (5.5%) basal cell carcinoma (BCC) and five actinic keratosis. The mean time to cancer onset was identified as 22 months after the start of four therapy, with an SD of 18 months, suggesting an earlier onset with respect to the start of therapy in our population. On univariate analysis, age (P = 0.001) and age of psoriasis onset (0.009) were statistically significant. Nine of 17 were skin cancers in the second group. Our study provided real-life evidence of the percentage of patients with skin cancers during therapy with anti-IL mAbs, demonstrating a good safety profile of the investigated drugs.","PeriodicalId":11830,"journal":{"name":"European Journal of Cancer Prevention","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-01-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142946696","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Human papillomavirus vaccination coverage in Italy. 意大利的人类乳头瘤病毒疫苗接种覆盖率。

IF 2.1 4区医学

European Journal of Cancer Prevention Pub Date : 2025-01-01 Epub Date: 2024-06-07 DOI: 10.1097/CEJ.0000000000000896

Giorgio Bogani, Giovanni Scambia, Francesco Raspagliesi, Giovanni Corso

引用次数: 0

Conditional survival of male breast cancer. 男性乳腺癌的条件生存率。

IF 2.1 4区医学

European Journal of Cancer Prevention Pub Date : 2025-01-01 Epub Date: 2024-05-06 DOI: 10.1097/CEJ.0000000000000893

Yanshuai Fan, Chaoyue Ku, Ruizhe Wang, Binbin Wu, Man Cui, Juan Wang, Miao Deng, Li Liu, Zhiguang Ping

{"title":"Conditional survival of male breast cancer.","authors":"Yanshuai Fan, Chaoyue Ku, Ruizhe Wang, Binbin Wu, Man Cui, Juan Wang, Miao Deng, Li Liu, Zhiguang Ping","doi":"10.1097/CEJ.0000000000000893","DOIUrl":"10.1097/CEJ.0000000000000893","url":null,"abstract":"Background: The incidence of male breast cancer has been increasing in recent years; however, the long-term survival outcomes of diagnosed patients remain uncertain. This study was designed to evaluate the conditional survival of male breast cancer patients and to predict the future survival of patients through the conditional nomogram, to provide important suggestions for clinical decision-making.Methods: Retrospective data from the SEER database included 3600 male breast cancer patients, divided into training and validation groups (7 : 3 ratio). Overall survival rates were calculated using Kaplan-Meier analysis. Conditional survival analysis described survival at specific years. Time-dependent multivariate Cox analysis identified prognostic factors' impact. The conditional survival nomogram model predicted real-time survival rates.Results: Over time, the 5-year real-time survival rate of patients gradually improved, increasing from 70.5 to 74.8, 79.4, 85.8, and 92.9% (respectively, representing 5-year survival rates of 1-4 years after diagnosis). In addition, the improvement in conditional survival rate CS5 showed a nonlinear trend. After 5 years of diagnosis, age, tumor size, and tumor stage had a sustained impact on patient prognosis. Finally, a conditional survival nomogram was constructed to predict the 10-year survival rate in real time.Conclusion: Five years after diagnosis, the conditional survival rate of male patients with breast cancer has improved, but it is not nonlinear. In the first 5 years after diagnosis, patients with older age, larger tumor size, poorer tumor stage, and distant metastasis should be actively followed up and treated to improve their long-term survival.","PeriodicalId":11830,"journal":{"name":"European Journal of Cancer Prevention","volume":" ","pages":"66-75"},"PeriodicalIF":2.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140897540","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Oncoplastic breast surgery: where are we now. 乳房肿瘤整形手术：我们现在在哪里？

IF 2.1 4区医学

European Journal of Cancer Prevention Pub Date : 2025-01-01 Epub Date: 2024-12-04 DOI: 10.1097/CEJ.0000000000000923

Francesca De Lorenzi, Mario Alessandri-Bonetti

引用次数: 0

Physical activity and exercise health benefits: cancer prevention, interception, and survival. 体育活动和锻炼对健康的益处：癌症预防、拦截和生存。

IF 2.1 4区医学

European Journal of Cancer Prevention Pub Date : 2025-01-01 Epub Date: 2024-06-26 DOI: 10.1097/CEJ.0000000000000898

Adriana Albini, Carlo La Vecchia, Francesca Magnoni, Ornella Garrone, Danilo Morelli, Jaak Ph Janssens, Alain Maskens, Gad Rennert, Viviana Galimberti, Giovanni Corso

{"title":"Physical activity and exercise health benefits: cancer prevention, interception, and survival.","authors":"Adriana Albini, Carlo La Vecchia, Francesca Magnoni, Ornella Garrone, Danilo Morelli, Jaak Ph Janssens, Alain Maskens, Gad Rennert, Viviana Galimberti, Giovanni Corso","doi":"10.1097/CEJ.0000000000000898","DOIUrl":"10.1097/CEJ.0000000000000898","url":null,"abstract":"Physical activity (PA) has an established role in the promotion of health and fitness and the prevention of disease. Expected overall benefits include reduction of all-cause morbidity and death, weight control, improved quality of life, improved bone health and decreased falls of elderly subjects, , deeper cognition, and reduced risk of depression, anxiety, and sleeplessness. Currently, PA is a mainstay in the management of cardiovascular diseases, metabolic syndrome, diabetes, and bone health. Recently, the perception of its role in primary and secondary prevention, interception, and treatment of cancer, however, is also gaining importance. Regular walking, the simplest type of PA, is associated with reduced all-cause and cardiovascular disease mortality, and a role in cancer prevention is of increasing interest. Furthermore, PA improves the quality of life of cancer patients, attenuating side effects of chemotherapy, decreasing sarcopenia, increasing fitness, and inhibiting the recurrence and progression of some cancer types. It promotes emotional and psychological benefits in patients, inducing positive changes. While mechanisms, effective levels and useful amount of PA practice are well established in cardiology, they are yet to be fully determined in oncology. Nevertheless, PA is recommended to reduce cancer risk in the general population, and it has been introduced in programs for the prevention of second cancers. In perspective, it will help as integrative therapy in cancer patients and for cancer survivors. The number of beneficial effects in the cancer continuum is highlighted in this review.","PeriodicalId":11830,"journal":{"name":"European Journal of Cancer Prevention","volume":" ","pages":"24-39"},"PeriodicalIF":2.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141450148","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cardiovascular death risk in patients with solid tumors: a population-based study in the United States. 实体瘤患者的心血管死亡风险：一项基于美国人口的研究。

IF 2.1 4区医学

European Journal of Cancer Prevention Pub Date : 2025-01-01 Epub Date: 2024-08-26 DOI: 10.1097/CEJ.0000000000000921

Shuaijie Gao, Hao Zhu, Xinyu Chang, Xiting Cao, Zhenwei Wang, Xiaoxuan Chu, Lu Zhang, Xinhua Wang, Jie Lu

{"title":"Cardiovascular death risk in patients with solid tumors: a population-based study in the United States.","authors":"Shuaijie Gao, Hao Zhu, Xinyu Chang, Xiting Cao, Zhenwei Wang, Xiaoxuan Chu, Lu Zhang, Xinhua Wang, Jie Lu","doi":"10.1097/CEJ.0000000000000921","DOIUrl":"10.1097/CEJ.0000000000000921","url":null,"abstract":"Background: Previous studies have focused on the risk of cardiovascular disease (CVD)-specific death in hematological cancers and in some single anatomical tumor sites, there remains a paucity of data on systematic analyses in solid tumors.Objective: The objective of this study is to evaluate the distribution, risk, and trends of CVD-specific death in patients with solid tumors.Methods: A total of 2 679 293 patients with solid tumors diagnosed between 1975 and 2019 were screened from the Surveillance, Epidemiology and End Results (SEER) program across 15 anatomical sites. Standardized mortality ratios (SMRs) and absolute excess risks (AERs) were used to describe the intensity of CVD-specific death, competing risk regression models were used to assess the risk of CVD-specific death, and restricted cubic spline analyses were employed to investigate the potential linear or nonlinear relationship between age and CVD death.Results: CVD-specific death in patients with solid tumors accounted for 48.95% of non-cancer deaths. Compared with the general population, patients with solid tumors had higher SMR and AER of CVD death (SMR: 1.15; AER: 21.12), heart disease-related death (SMR: 1.13; AER: 13.96), and cerebrovascular disease-related death (SMR: 1.20; AER: 4.85). Additionally, the SMR exhibited a decreasing trend with increasing time to diagnosis. Furthermore, a nonlinear relationship was observed between age and CVD-specific death in patients with solid tumors of different systems.Conclusion: CVD-specific death accounted for a large proportion of the cause of non-cancer deaths. Patients with solid tumors exhibit an elevated risk of CVD-specific death. Screening for CVD death and optimizing risk management in patients with solid tumors throughout anticancer treatment may be beneficial in preventing CVD death.","PeriodicalId":11830,"journal":{"name":"European Journal of Cancer Prevention","volume":" ","pages":"11-23"},"PeriodicalIF":2.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142125179","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0