Equine Veterinary Education最新文献

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Uterine rupture 子宫破裂
IF 1.1 4区 农林科学
Equine Veterinary Education Pub Date : 2026-09-02 Epub Date: 2026-04-16 DOI: 10.1111/eve.70110
C. Russell
{"title":"Uterine rupture","authors":"C. Russell","doi":"10.1111/eve.70110","DOIUrl":"https://doi.org/10.1111/eve.70110","url":null,"abstract":"","PeriodicalId":11786,"journal":{"name":"Equine Veterinary Education","volume":"38 10","pages":"511-514"},"PeriodicalIF":1.1,"publicationDate":"2026-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148872098","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Correction of equine angular limb deformities with radial osteotomy 桡骨截骨术矫正马角肢畸形
IF 1.1 4区 农林科学
Equine Veterinary Education Pub Date : 2026-09-02 Epub Date: 2026-07-22 DOI: 10.1111/eve.70156
J. F. Hawkins
{"title":"Correction of equine angular limb deformities with radial osteotomy","authors":"J. F. Hawkins","doi":"10.1111/eve.70156","DOIUrl":"https://doi.org/10.1111/eve.70156","url":null,"abstract":"","PeriodicalId":11786,"journal":{"name":"Equine Veterinary Education","volume":"38 10","pages":"533-535"},"PeriodicalIF":1.1,"publicationDate":"2026-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148871929","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Practical approach to clinically diagnosed equine sarcoids using diode laser excision: Results and long-term outcome 应用二极管激光切除临床诊断马肉瘤的实用方法:结果和长期预后
IF 1.1 4区 农林科学
Equine Veterinary Education Pub Date : 2026-09-02 Epub Date: 2026-02-24 DOI: 10.1111/eve.70071
M. C. Fioretti, D. A. Singleton, S. Z. Barakzai
{"title":"Practical approach to clinically diagnosed equine sarcoids using diode laser excision: Results and long-term outcome","authors":"M. C. Fioretti,&nbsp;D. A. Singleton,&nbsp;S. Z. Barakzai","doi":"10.1111/eve.70071","DOIUrl":"https://doi.org/10.1111/eve.70071","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>A recent systematic review reported insufficient evidence to conclude on a preferred treatment for equine sarcoids. Diode laser excision of sarcoids is now one of the most common first-line treatments in UK practices but there is limited evidence of its long-term efficacy.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>This study aimed to evaluate the overall recurrence rate of sarcoids, the recurrence rate at the site of surgical excision (SSE) and at different anatomical sites (DAS) after diode laser excision in clinical practice.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Study Design</h3>\u0000 \u0000 <p>Retrospective case series.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Medical records for horses that underwent surgical excision for clinically diagnosed sarcoid lesions using a diode laser between 2018 and 2023 by a single experienced ECVS diplomate were retrospectively reviewed. Horses that were already receiving additional sarcoid treatment at the time of surgery, histological exclusion of sarcoids or those that were unavailable for follow-up were excluded. Signalment, lesion type, size and location, histology results, surgical complications, recurrence of sarcoid(s) at the SSE and at DAS and time of recurrence were recorded and analysed.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>One hundred and twenty-four horses with 218 lesions were included with a median follow-up of 32 months [6.0–71.2]. The recurrence rate for an individual sarcoid at the SSE was low (6.4%), and the overall recurrence rate per horse (at least one recurrence anywhere) was 20.5%. Obtaining histological tumour-free margins (TFM) was associated with a significant decrease in recurrence rate at SSE (0.0% vs. 11.5%, Fisher test: <i>p</i> = 0.01).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Main Limitations</h3>\u0000 \u0000 <p>Retrospective study design, not all lesions were confirmed histologically.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Diode laser removal is an effective treatment for equine sarcoids, with an overall low recurrence rate observed. Recurrence at the SSE was significantly reduced if TFM were obtained on the excised lesion. Careful selection of lesions and sufficient margins appear to be important for treatment success.</p>\u0000 </section>\u0000 </div>","PeriodicalId":11786,"journal":{"name":"Equine Veterinary Education","volume":"38 10","pages":"e752-e759"},"PeriodicalIF":1.1,"publicationDate":"2026-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148871973","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Early-stage crystalluria-associated cystitis in a horse: Diagnostic value of serial urine sediment examination 马早期结晶性尿相关性膀胱炎:连续尿沉渣检查的诊断价值
IF 1.1 4区 农林科学
Equine Veterinary Education Pub Date : 2026-09-02 Epub Date: 2026-06-29 DOI: 10.1111/eve.70139
R. Sato, S. Imai, A. Yamazaki, T. Miyazaki
{"title":"Early-stage crystalluria-associated cystitis in a horse: Diagnostic value of serial urine sediment examination","authors":"R. Sato,&nbsp;S. Imai,&nbsp;A. Yamazaki,&nbsp;T. Miyazaki","doi":"10.1111/eve.70139","DOIUrl":"https://doi.org/10.1111/eve.70139","url":null,"abstract":"<p>Calcium carbonate crystals are commonly observed in equine urine; however, crystalluria without urolith formation rarely results in clinically significant disease. A 4-year-old Japanese Sport Horse developed recurrent haematuria accompanied by the presence of numerous angular calcium carbonate crystals. Discontinuing the calcium supplementation and increasing dietary salt to promote water intake resulted in a reduction in crystal size and a change to a more rounded morphology after 3 months, although haematuria recurred. Ultrasonography revealed accumulation of sand-like material within the bladder and subjective thickening of the bladder and urethra walls. Urine culture yielded Gram-negative coccobacilli and 16S rRNA gene sequencing identified the organism as <i>Acinetobacter pseudolwoffi</i>. Further dietary management resulted in further reduction of crystal size and morphology comparable to those of a healthy control horse, with complete resolution of haematuria. No recurrence has been observed over 3 years. This case highlights the value of serial urine sediment examination for detecting changes in crystalluria and guiding noninvasive management of equine lower urinary tract disease.</p>","PeriodicalId":11786,"journal":{"name":"Equine Veterinary Education","volume":"38 10","pages":"e690-e697"},"PeriodicalIF":1.1,"publicationDate":"2026-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/eve.70139","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148872174","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Diagnosis and surgical treatment of four radiographically incomplete, articular, proximal third metatarsal bone fractures 四例放射学表现不全的第三跖近端关节骨折的诊断和手术治疗
IF 1.1 4区 农林科学
Equine Veterinary Education Pub Date : 2026-09-02 Epub Date: 2026-05-12 DOI: 10.1111/eve.70117
M. J. S. Duggan, I. Wright, A. Campos Schweitzer, F. Rossignol, E. Cillán García, W. Schofield
{"title":"Diagnosis and surgical treatment of four radiographically incomplete, articular, proximal third metatarsal bone fractures","authors":"M. J. S. Duggan,&nbsp;I. Wright,&nbsp;A. Campos Schweitzer,&nbsp;F. Rossignol,&nbsp;E. Cillán García,&nbsp;W. Schofield","doi":"10.1111/eve.70117","DOIUrl":"https://doi.org/10.1111/eve.70117","url":null,"abstract":"<p>The objective was to describe the diagnosis, surgical repair and outcome of four radiographically incomplete, articular, proximal third metatarsal bone fractures with an uncommon, dorsomedial–plantarolateral oblique configuration and this is a retrospective analysis of four racehorses presenting for surgical treatment of this uncommon fracture configuration to four different hospitals in Ireland, England, Scotland and France. Four horses were included, each presenting with acute hindlimb lameness following fast exercise. The cases involved a 4-year-old Standardbred mare used for racing, a 5-year-old Thoroughbred mare used for jump racing, a 7-year-old Thoroughbred gelding also used for jump racing and a 6-year-old French Trotter mare. Clinical features included marked lameness, mild swelling and pain on palpation of the proximal metatarsal region. The fracture location and configuration were consistently identified by D40-50°M-PlLO radiographical projections. All cases were repaired using screws placed in lag fashion but one case subsequently required double plate fixation due to fracture propagation. Three horses returned to their previous level of exercise between 7 and 8 months and successfully raced between 9- and 14-month postoperatively with two horses subsequently winning. One horse was retired to stud as a broodmare. It was concluded that accurate diagnosis and surgical repair of this fracture type can result in a good outcome and return to athletic function in affected racehorses.</p>","PeriodicalId":11786,"journal":{"name":"Equine Veterinary Education","volume":"38 10","pages":"e721-e728"},"PeriodicalIF":1.1,"publicationDate":"2026-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/eve.70117","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148871879","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Mitral regurgitation and decompensated heart failure in a young pregnant pony mare: An aetiological challenge 二尖瓣反流和失代偿性心力衰竭在一个年轻的怀孕小马母马:一个病因挑战
IF 1.1 4区 农林科学
Equine Veterinary Education Pub Date : 2026-09-02 Epub Date: 2026-05-22 DOI: 10.1111/eve.70121
M. F. David, L. Cannon, A. Tortereau, A. Thomas-Cancian, I. Desjardins
{"title":"Mitral regurgitation and decompensated heart failure in a young pregnant pony mare: An aetiological challenge","authors":"M. F. David,&nbsp;L. Cannon,&nbsp;A. Tortereau,&nbsp;A. Thomas-Cancian,&nbsp;I. Desjardins","doi":"10.1111/eve.70121","DOIUrl":"https://doi.org/10.1111/eve.70121","url":null,"abstract":"<p>A 4-year-old, 6-month pregnant, Welsh pony mare presented with severe acute clinical signs including depression, anorexia, pale mucous membranes, tachycardia with a grade 4/6 holosystolic murmur and moderate expiratory dyspnoea with diffuse wheezes. There was no evidence of placentitis or fetal distress. Electrocardiography showed sinus tachycardia. Echocardiography revealed atrial and ventricular dilatation, pulmonary artery enlargement, irregular hyperechoic thickening of the mitral valve (MV) leaflets, with moderate to severe regurgitation and severely impaired systolic function. Thoracic radiographs were consistent with pulmonary oedema. Congenital MV dysplasia or early degenerative valve disease was suspected. Left heart failure did not respond to emergency treatment, and the pony developed severe jugular venous distension and pulsation. Due to the poor prognosis, euthanasia was elected. Post-mortem examination revealed thickening of the mitral leaflets, predominantly the septal cusp, and severe four-chamber dilatation, with no other cardiac lesions. Histological examination showed myxoid valvular degeneration but did not allow differentiation between congenital dysplasia and early degenerative disease. In this case, physiological effects of gestation may have exacerbated the deleterious haemodynamic effects on mitral insufficiency.</p>","PeriodicalId":11786,"journal":{"name":"Equine Veterinary Education","volume":"38 10","pages":"e676-e685"},"PeriodicalIF":1.1,"publicationDate":"2026-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/eve.70121","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148871880","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of polymyxin B on survival in strangulating small intestinal lesions 多粘菌素B对绞窄性小肠病变存活的影响
IF 1.1 4区 农林科学
Equine Veterinary Education Pub Date : 2026-09-02 Epub Date: 2026-04-10 DOI: 10.1111/eve.70100
O. A. Taylor, A. R. E. Jones, H. A. Stone, T. S. Mair
{"title":"Effect of polymyxin B on survival in strangulating small intestinal lesions","authors":"O. A. Taylor,&nbsp;A. R. E. Jones,&nbsp;H. A. Stone,&nbsp;T. S. Mair","doi":"10.1111/eve.70100","DOIUrl":"https://doi.org/10.1111/eve.70100","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Polymyxin B is an antibiotic that targets gram-negative bacteria by binding to lipopolysaccharide on the outer membrane of the bacteria, the endotoxin responsible for triggering systemic inflammation. Endotoxaemia is common in horses with small intestinal strangulating lesions. Although polymyxin B has been shown to reduce endotoxaemic effects in experimental studies, the efficacy in clinical cases remains unclear.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>To investigate whether polymyxin B influences survival to discharge on both an univariable and multivariable level. To investigate the effect that confounding factors may have on the survival to discharge.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Study Design</h3>\u0000 \u0000 <p>Prospective, controlled study, alternating treatment and control groups.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Case details, lesion, segment affected, length of ischaemic intestine and type of anastomosis (if required) were recorded using a data collection sheet created by one clinician. All horses were alternately assigned to receive polymyxin B or nothing and their survival to discharge was recorded. The use of post-operative lidocaine and clinical parameters at admission were also recorded.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Univariable analysis showed a higher survival rate in horses that received polymyxin B compared with those that did not. Multivariable logistic regression, when controlling for heart rate, PCV and age, abolished this effect. Findings show polymyxin B was not an independent predictor of survival.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Main Limitations</h3>\u0000 \u0000 <p>Limited case numbers, non-blinded study, long study period, lack of placebo and lack of confirmation of endotoxaemia.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>The use of polymyxin B in strangulating small intestinal lesions was not found to be statistically significant on survival to discharge as an independent predictor.</p>\u0000 </section>\u0000 </div>","PeriodicalId":11786,"journal":{"name":"Equine Veterinary Education","volume":"38 10","pages":"e729-e735"},"PeriodicalIF":1.1,"publicationDate":"2026-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148872015","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Fetlock varus correction in a horse using a radial osteotomy of the distal third metacarpus 马第三掌骨远端桡骨切开术矫正费特洛克内翻
IF 1.1 4区 农林科学
Equine Veterinary Education Pub Date : 2026-09-02 Epub Date: 2026-03-15 DOI: 10.1111/eve.70080
J. L. Gaida, J. L. Kamm, M. J. Huber
{"title":"Fetlock varus correction in a horse using a radial osteotomy of the distal third metacarpus","authors":"J. L. Gaida,&nbsp;J. L. Kamm,&nbsp;M. J. Huber","doi":"10.1111/eve.70080","DOIUrl":"https://doi.org/10.1111/eve.70080","url":null,"abstract":"<div>\u0000 \u0000 <p>Angular limb deformities in horses with closed physes present a significant surgical challenge due to limited corrective options. This case report discusses a novel approach using a radial osteotomy at the centre of rotation and angulation with a crescentic saw blade and two locking compression plates (LCPs) to correct metacarpophalangeal deformity in a 10-month-old colt. The horse presented with right front fetlock varus, physeal closure of distal third metacarpus (MCIII), AAEP grade 4/5 lameness, and subluxation with degenerative joint disease of the metacarpophalangeal joint. A prior attempt for growth retardation using a transphyseal screw did not result in correction. A radial osteotomy was performed proximal to the distal physis of MCIII using a crescentic saw blade. Axial alignment was achieved by rotating the distal fragment of MCIII laterally in the frontal plane and fixated with two narrow 4.5 mm LCPs. Complications after surgery included surgical site infection, incisional dehiscence and progressive degenerative joint disease. Twenty weeks post-surgery the surgical site was completely healed, and the horse was sound at the walk. Radiographs showed correction of the varus deformity from 15° to 2°. No reports exist of a radial osteotomy using a crescentic saw blade for surgical correction of a metacarpophalangeal deviation in a horse.</p>\u0000 </div>","PeriodicalId":11786,"journal":{"name":"Equine Veterinary Education","volume":"38 10","pages":"e714-e720"},"PeriodicalIF":1.1,"publicationDate":"2026-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148872096","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Epidermoid cyst as differential diagnosis for spherical keratoma: What do we know? 表皮样囊肿作为球形角化瘤的鉴别诊断:我们知道些什么?
IF 1.1 4区 农林科学
Equine Veterinary Education Pub Date : 2026-08-05 Epub Date: 2026-06-29 DOI: 10.1111/eve.70144
R. Goodman-Davis, D. C. Debald, R. Haralambus
{"title":"Epidermoid cyst as differential diagnosis for spherical keratoma: What do we know?","authors":"R. Goodman-Davis,&nbsp;D. C. Debald,&nbsp;R. Haralambus","doi":"10.1111/eve.70144","DOIUrl":"https://doi.org/10.1111/eve.70144","url":null,"abstract":"<p>This article briefly presents the case of a space-occupying coronary band mass that raised the question of how one can differentiate between two uncommonly seen but now commonly paired differential diagnoses and prompted a review of the relevant literature. For over 20 years, spherical keratoma and epidermoid cyst (EC) have been given as differential diagnoses for benign space-occupying masses of the foot with the understanding that the two must be and could be differentiated only by histological examination. However, nowhere in the literature is it specified how these two structures differ histologically, leading to a diagnostic conundrum for pathologists and surgeons alike. This article reviews the relevant literature in both equine and human medicine, on which the equine world's understanding of ECs is based, finds the two histologically indistinguishable and suggests these terms are in fact not differentials, but rather that a spherical keratoma may be a type of EC, and that histological evidence from the scarcely documented subungual epidermoid inclusion cyst in humans could provide insight into the pathogenesis of spherical keratoma formation in horses. The authors do not offer unequivocal answers but seek to highlight the complexity of the topic, suggesting categorisation may be influenced by location and suspected aetiology more than by histological characterisation.</p>","PeriodicalId":11786,"journal":{"name":"Equine Veterinary Education","volume":"38 9","pages":"489-508"},"PeriodicalIF":1.1,"publicationDate":"2026-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/eve.70144","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148696613","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Serial investigation of Lawsonia intracellularis seroprevalence and shedding in Thoroughbred foals during the first year 一年内纯种马驹细胞内裂毛线虫血清流行及脱落情况的系列调查
IF 1.1 4区 农林科学
Equine Veterinary Education Pub Date : 2026-08-05 Epub Date: 2026-07-06 DOI: 10.1111/eve.70115
C. Ribonnet, V. A. Colgate, N. Robinson, M. Cubitt, C. Bolton, E. Floyd
{"title":"Serial investigation of Lawsonia intracellularis seroprevalence and shedding in Thoroughbred foals during the first year","authors":"C. Ribonnet,&nbsp;V. A. Colgate,&nbsp;N. Robinson,&nbsp;M. Cubitt,&nbsp;C. Bolton,&nbsp;E. Floyd","doi":"10.1111/eve.70115","DOIUrl":"https://doi.org/10.1111/eve.70115","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>There are no studies reporting seroprevalence and faecal shedding <i>of Lawsonia intracellularis</i> (<i>L. intracellaris</i>) in UK foals during their first year of life.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>To determine seroprevalence and faecal shedding for <i>L. intracellularis</i> in Thoroughbred mares and foals in the United Kingdom. To evaluate associations between clinicopathologic parameters and serology titres in foals.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Study design</h3>\u0000 \u0000 <p>Single-centre prospective cohort study.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Foals from six farms underwent clinical examination, blood sampling for haematology and biochemistry, serum immunoperoxidase monolayer assay (IPMA) for analysis of antibodies against <i>L. intracellularis</i>, and faecal PCR at birth, 3, 6, 9 and 12 months of age. A blood sample was collected from the dams at time point 0 for IPMA analysis.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Forty-seven foals from six different farms were enrolled and 37 completed the entire study. At foaling, 77% (95% CI: 64%–88%) of mares and 64% (95% CI: 50%–77%) of foals were seropositive. There was a positive linear relationship between mare and foal serum titres (rho = 0.723; p &lt; 0.001) and between foal serum titres and immunoglobulin G (IgG) levels (rho = 0.38; <i>p</i> = 0.008). Peak timing for seroconversion occurred between 6 and 9 months of age and between September and January. Only 2 faecal PCR samples tested positive, and no clinical signs of disease were recognised in any foal. Twenty-nine out of 37 foals (78%; 95% CI: 65%–92%) did not seroconvert between 3 and 12 months of age.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Main limitations</h3>\u0000 \u0000 <p>Convenience sample encompassing a small number of farms and foals recruited from a single county.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>This study suggests frequent exposure to <i>L. intracellularis</i> on UK Thoroughbred stud farms. Peak timing of seroconversion was between 6 and 9 months of age.</p>\u0000 </section>\u0000 </div>","PeriodicalId":11786,"journal":{"name":"Equine Veterinary Education","volume":"38 9","pages":"e650-e659"},"PeriodicalIF":1.1,"publicationDate":"2026-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148695880","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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