Medica Hospitalia : Journal of Clinical Medicine最新文献_第3页

FAKTOR RISIKO KEMATIAN PADA KASUS PROBABLE COVID-19 DI RSUP Dr. KARIADI SEMARANG 风险因素 KEMATIAN PADA KASUS PROBABLE COVID-19 DI RSUP Dr KARIADI SEMARANG

Medica Hospitalia : Journal of Clinical Medicine Pub Date : 2023-11-29 DOI: 10.36408/mhjcm.v10i3.957

Yui Prashandika, S. G. Pramudo, Sigid Kirana Lintang Bhima, Tuntas Dhanardhono

{"title":"FAKTOR RISIKO KEMATIAN PADA KASUS PROBABLE COVID-19 DI RSUP Dr. KARIADI SEMARANG","authors":"Yui Prashandika, S. G. Pramudo, Sigid Kirana Lintang Bhima, Tuntas Dhanardhono","doi":"10.36408/mhjcm.v10i3.957","DOIUrl":"https://doi.org/10.36408/mhjcm.v10i3.957","url":null,"abstract":"LATAR BELAKANG : Sebuah penelitian yang membandingkan karakteristik pasien yang meninggal karena infeksi COVID-19 mendapatkan hasil bahwa kasus kematian banyak ditemukan pada pasien dengan riwayat komorbid seperti hipertensi, diabetes, penyakit jantung, penyakit ginjal, dan penyakit paru kronis, dan keganasan. Salah satu definisi probable COVID- 19 menurut WHO adalah kasus suspect dengan gambaran radiologis mengarah ke infeksi COVID-19. METODE : Penelitian ini dilakukan dengan desain observasional analitik dengan pendekatan cross-sectional. Teknik sampling yang digunakan adalah teknik consecutive sampling dengan minimal sampel sebanyak 57 rekam medis pasien probable COVID-19. Data yang terkumpul akan dilakukan analisis menggunakan program SPSS secara univariat, bivariat, dan multivariat. HASIL : Pasien probable COVID-19 mayoritas mengalami kematian yaitu sebanyak 65 subjek (91,5%), sedangkan pasien hidup hanya 6 subjek (8,5%). Faktor risiko komorbid seperti pneumoniae (p=0,151), penyakit paru menahun (p=0,764), penyakit jantung (p=0,591), hipertensi (p=0,254), DM (p=0,361), penyakit ginjal (p=0,523) dan keganasan (p=0,523) tidak menunjukan hubungan yang signifikan terhadap kematian probable COVID-19. KESIMPULAN : Faktor risiko komorbiditas pneumoniae, penyakit paru menahun, penyakit jantung, hipertensi, DM, penyakit ginjal , dan keganasan tidak menunjukan hubungan yang signifikan terhadap kematian probable COVID-19 di RSUP dr Kariadi Semarang. Kata Kunci : Faktor Risiko ; Probable COVID-19 ; Kematian","PeriodicalId":117574,"journal":{"name":"Medica Hospitalia : Journal of Clinical Medicine","volume":"20 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139209939","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Pengaruh Variasi Pasta Gigi Terhadap Kekuatan Tarik Elastik Ortodontik Lateks & Non-Lateks 牙膏变化对乳胶和非乳胶正畸弹性拉伸强度的影响

Medica Hospitalia : Journal of Clinical Medicine Pub Date : 2023-11-29 DOI: 10.36408/mhjcm.v10i3.996

Indryasari, Budi Wibowo, Indah Lestari Vidyahayati

{"title":"Pengaruh Variasi Pasta Gigi Terhadap Kekuatan Tarik Elastik Ortodontik Lateks & Non-Lateks","authors":"Indryasari, Budi Wibowo, Indah Lestari Vidyahayati","doi":"10.36408/mhjcm.v10i3.996","DOIUrl":"https://doi.org/10.36408/mhjcm.v10i3.996","url":null,"abstract":"Latar Belakang : Elastik ortodontik merupakan salah satu alat yang digunakan pada perawatan ortodontik. Berdasarkan jenis bahan elastik ortodontik terbagi menjadi elastik ortodontik lateks & non-lateks. Secara klinis elastik ortodontik mengalami penurunan kekuatan tarik yang dapat dipengaruhi berbagai faktor termasuk pH saliva dan penggunaan pasta gigi. Kandungan SLS pada pasta gigi dapat meningkatkan pH saliva sehingga menyebabkan penurunan kekuatan tarik. Tujuan : Penelitian ini bertujuan untuk menganalisis pengaruh variasi pasta gigi terhadap kekuatan tarik elastik ortodontik lateks dan non-lateks. Metode : Penelitian ini merupakan penelitian eksperimental laboratoris dengan post-test only control group design. Sampel penelitian terdiri dari 15 sampel elastik ortodontik lateks dan 15 sampel elastik ortodontik non-lateks merek American Orthodontics dengan diameter 1⁄4 inchi. Sampel terbagi kedalam 3 kelompok perlakuan dengan variasi jenis elastik disetiap kelompoknya, sampel akan direndam selama 24 jam. Kekuatan tarik akan diukur menggunakan alat Imada Motorized Tensile test MV 110 dan akan dianalisis menggunakan uji One Way Anova. Hasil : Hasil uji One Way Anova menunjukkan tidak terdapat perbedaan yang signifikan antara kelompok kontrol, kelompok pasta gigi detergen dan kelompok pasta gigi non-detergen dengan nilai p = 0,757 (p > 0,05) untuk lateks dan p = 0,382 (p > 0,05) untuk non-lateks Kesimpulan : Pasta gigi detergen dan non-detergen tidak mempengaruhi kekuatan tarik elastik ortodontik lateks & non-lateks.","PeriodicalId":117574,"journal":{"name":"Medica Hospitalia : Journal of Clinical Medicine","volume":"20 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139210217","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Body Composition and Its Related with Hypertension in Elderly in Surakarta 苏腊卡尔塔老年人的身体成分及其与高血压的关系

Medica Hospitalia : Journal of Clinical Medicine Pub Date : 2023-11-29 DOI: 10.36408/mhjcm.v10i3.873

Wahyu Tri Sudaryanto, Wahyuni Wahyuni, Isnaini Herawati, Ika Yuli Ayuningrum, Bhisma Murti, Rizki Setiawan, Nuristiqomah Dwi Putri

{"title":"Body Composition and Its Related with Hypertension in Elderly in Surakarta","authors":"Wahyu Tri Sudaryanto, Wahyuni Wahyuni, Isnaini Herawati, Ika Yuli Ayuningrum, Bhisma Murti, Rizki Setiawan, Nuristiqomah Dwi Putri","doi":"10.36408/mhjcm.v10i3.873","DOIUrl":"https://doi.org/10.36408/mhjcm.v10i3.873","url":null,"abstract":"BACKGROUND: Several studies reported that obesity are linked to abnormal blood pressure. Body composition has been commonly measured using basic anthropometry including body mass index (BMI) or waist circumference (WC). OBJECTIVE: The aim of this study was to compare body composition (body mass index and central obesity) on hypertension in elderly. METHOD: A cross sectional study was carried out in Surakarta, Central Java. A sample of 91 elderly was selected by accidental sampling. The dependent variable was hypertension. The independent variables were age, gender, body mass index (BMI), and central obesity. BMI and central obesity was used to measure body composition. Blood pressure was measured by sphygmomanometer, body weight was measured by digital scale (kg), and body height was measured by stature meter (cm). Central obesity was categorized by waist circumference (WC in centimeter) measurement. The other variables were obtained from questionnaire. Comparison of body composition on hypertension were examined using simple logistic regression run on Stata 13. RESULTS: Overweight (OR= 12.00; 95% CI= 0,81 to 177.44; p= 0.071) and obesity (OR= 10.4; 95% CI= 0.78 to 137.83; p= 0.076) in older peole increased the risk of hypertension and it was statistically marginally significant. Elderly with central obesity (waist circumference ≥94 cm for male or ≥80 cm for female) had higher risk to hypertension and it was statistically significant (OR= 3.07; 95% CI= 1.10 to 8.53; p= 0.032). CONCLUSION: High body compositions (overweight, obesity, or central obesity) increase the risk of hypertension in elderly.","PeriodicalId":117574,"journal":{"name":"Medica Hospitalia : Journal of Clinical Medicine","volume":"36 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139210671","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Rare case of of Enlargment dextro Inguinal Endometriosis TissueLump : Case Report and Literature review 右腹股沟子宫内膜异位症组织肿块增大的罕见病例：病例报告和文献综述

Medica Hospitalia : Journal of Clinical Medicine Pub Date : 2023-11-29 DOI: 10.36408/mhjcm.v10i3.1019

Indra Adi Susianto, Edward Hartono, Barkah Fajar Riyadi, Siti Amarwati, Alberta Widya Kristanti, Aprilia Karen Mandagie, Mohammad Haekal

{"title":"Rare case of of Enlargment dextro Inguinal Endometriosis TissueLump : Case Report and Literature review","authors":"Indra Adi Susianto, Edward Hartono, Barkah Fajar Riyadi, Siti Amarwati, Alberta Widya Kristanti, Aprilia Karen Mandagie, Mohammad Haekal","doi":"10.36408/mhjcm.v10i3.1019","DOIUrl":"https://doi.org/10.36408/mhjcm.v10i3.1019","url":null,"abstract":"Background : Endometriosis is usually found in intrapelvic structures such as the ovaries, peritoneum, gynecological organs and the pouch of Douglas. We report an unusual case of endometriosis in the right inguinal region. Cases : A 36-year-old woman with a history of laparoscopic surgery for endometriosis 4 years ago complained of catamenial pain and a mass in the right inguinal region, and her symptoms fluctuated with the menstrual cycle. An indistinct firm mass palpable in the right inguinal region. Ultrasound examination revealed a 2 × 1 cm mass in front of the pubic area on the lower edge of the rectus abdominis muscle. In a patient with an inguinal subcutaneous mass who complains of periodic changes in symptoms, endometriosis should be considered in the differential diagnosis. Conclusion : The low incidence of inguinal endometriosis is one of the considerations in the different diagnosis of painful inguinal hernias in the inguinal area in women with childbearing age. The diagnosis of endometriosis can be demonstrated clearly on High-Definition Ultrasound by trained personnel. Surgery is the optional treatment and is curative in this case.","PeriodicalId":117574,"journal":{"name":"Medica Hospitalia : Journal of Clinical Medicine","volume":"42 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139210010","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Influence of inflammatory factors (IL-6, CRP, NLPR, D-Dimer, LDH) on the PaO2/FiO2 ratio, in patients with severe and critical degrees of COVID-19 炎症因子（IL-6、CRP、NLPR、D-二聚体、LDH）对重度和临界 COVID-19 患者 PaO2/FiO2 比率的影响

Medica Hospitalia : Journal of Clinical Medicine Pub Date : 2023-11-29 DOI: 10.36408/mhjcm.v10i3.1014

Yulia Octaviany Harnoto, A. Assagaf, Dewi Indah Noviana Pratiwi, M. Isa, I. Nurrasyidah, Erna Kusumawardhani

{"title":"Influence of inflammatory factors (IL-6, CRP, NLPR, D-Dimer, LDH) on the PaO2/FiO2 ratio, in patients with severe and critical degrees of COVID-19","authors":"Yulia Octaviany Harnoto, A. Assagaf, Dewi Indah Noviana Pratiwi, M. Isa, I. Nurrasyidah, Erna Kusumawardhani","doi":"10.36408/mhjcm.v10i3.1014","DOIUrl":"https://doi.org/10.36408/mhjcm.v10i3.1014","url":null,"abstract":"BACKGROUND: Several types of inflammatory biomarkers that are important in severe and critical Covid-19 infections include: levels of IL-6, C-reactive protein (CRP), lactate dehydrogenase (LDH), D-Dimer and neutrophil-lymphocyte platelet ratio (NLRP), which are independent variables. Meanwhile, the severity of Covid-19 infection can be determined by measuring the PaO2 /FiO2 ratio. However, the relationship between the PaO2/FiO2 ratio as the dependent variable is not yet known. AIMS: To analyze the relationship between PaO2/FiO2 ratio and inflammatory biomarkers in COVID-19 patients METHOD: An analytic observational study with a retrospective, cross-sectional approach. The research sample consisted of PCR-confirmed severe and critical COVID-19 patients who were treated in the isolation room of the Ulin Hospital in Banjarmasin from August–December 2021, who met the inclusion and exclusion criteria. Data analysis used the Spearman test to see the relationship between the PaO2/FiO2 ratio and various inflammatory markers. RESULT: 52 severe and critical patients were observed according to the research flow. The number of male and female subjects (32/20) was found. The mean age was 55.38 years. The correlation test found that: there was no significant relationship between the PaO2/FiO2 ratio and IL-6 (p = 0.964), but there was a negative correlation between the PaO2/FiO2 ratio and: a).CRP (p = 0.038), b).LDH ( p<0.001), c).NLPR (p = 0.013), and d). D-dimer (p<0.001). The inflammatory biomarkers NLPR, LDH, and D-dimer are important independent variables for the severity of COVID-19, namely the PaO2/FiO2 ratio. CONCLUSION: There are a significant correlation between the PaO2/FiO2 ratio to measure the severity of Covid-19 and several inflammatory biomarkers CRP, LDH, NLPR and D-dimer","PeriodicalId":117574,"journal":{"name":"Medica Hospitalia : Journal of Clinical Medicine","volume":"20 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139214796","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Relationship between Stress Level and Risk of Eating Disorder in Undergraduate Students during the COVID-19 Pandemic COVID-19 大流行期间大学生压力水平与饮食失调风险之间的关系

Medica Hospitalia : Journal of Clinical Medicine Pub Date : 2023-11-29 DOI: 10.36408/mhjcm.v10i3.953

Jessica Clara, Titis Hadiati, Innawati Jusup, Widodo Sarjana A.S.

{"title":"Relationship between Stress Level and Risk of Eating Disorder in Undergraduate Students during the COVID-19 Pandemic","authors":"Jessica Clara, Titis Hadiati, Innawati Jusup, Widodo Sarjana A.S.","doi":"10.36408/mhjcm.v10i3.953","DOIUrl":"https://doi.org/10.36408/mhjcm.v10i3.953","url":null,"abstract":"BACKGROUND: The prevalence of undergraduate students' stress before COVID-19 pandemic in Indonesia was 36.7-71.6%, where undergraduate students' age was classified as the age group for the onset of eating disorders. During the COVID-19 pandemic, students must continue their studies. However, modifications of daily routines in pandemic have a negative effect on mental health, increase negative stress (distress), and it could increase the incidence of eating disorders symptoms. AIMS: The purpose of this study was to find out the relationship between stress level in undergraduate student and the risk of eating disorder they might have during the COVID-19 Pandemic. METHOD: This study used cross sectional study design and conducted on June 2021. The subjects were 110 active students who studied in Faculty of Medicine Diponegoro University who was chosen using consecutive sampling technique. The Perceived Stress Scale-10 questionnaire was used to measure the students’ stress level for the past month and the Eating Attitude Test-26 questionnaire was used to determine the students' risk of having an eating disoder. Both questionnaires were selected because it has been proven as reliable questionnaires with high sensitivity and specificity (Cronbach's alpha >0.7). RESULT: The result showed that out of 110 students who have been subjects of this study, 25,5% of respondents experienced low stress, 68,2% of respondents experienced moderate stress, and 6,4% of respondents experienced high stress. It also showed that 4,5% of respondents have the risk of having an eating disorder. CONCLUSION: There is a significant correlation (p=0,005) between the stress level and risk of eating disorder with very weak positive relationship direction (r=0,097).","PeriodicalId":117574,"journal":{"name":"Medica Hospitalia : Journal of Clinical Medicine","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139210233","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Full Text Volume 10 Number 3 November 2023 全文第 10 卷第 3 号 2023 年 11 月

Medica Hospitalia : Journal of Clinical Medicine Pub Date : 2023-11-29 DOI: 10.36408/mhjcm.v10i3.1047

Kariadi General Hospital

引用次数: 0

KORELASI KADAR TESTOSTERON TOTAL DENGAN HBA1C SEBAGAI KONTROL GLIKEMIK PADA LAKI LAKI PENDERITA DIABETES MELLITUS TIPE 2 总睾酮水平与作为 2 型糖尿病男性血糖控制指标的 Hba1c 的相关性

Medica Hospitalia : Journal of Clinical Medicine Pub Date : 2023-11-29 DOI: 10.36408/mhjcm.v10i3.941

Raja Iqbal Mulya Harahap, N. Tristina, I. Nurhayati, Sylvia Rachmayati

{"title":"KORELASI KADAR TESTOSTERON TOTAL DENGAN HBA1C SEBAGAI KONTROL GLIKEMIK PADA LAKI LAKI PENDERITA DIABETES MELLITUS TIPE 2","authors":"Raja Iqbal Mulya Harahap, N. Tristina, I. Nurhayati, Sylvia Rachmayati","doi":"10.36408/mhjcm.v10i3.941","DOIUrl":"https://doi.org/10.36408/mhjcm.v10i3.941","url":null,"abstract":"LATAR BELAKANG : Diabetes Mellitus Tipe 2 (DMT2) mampu menyebabkan berbagai komplikasi akibat terbentuknya advanced glycation end products (AGEs). AGEs dapat merusak berbagai organ dalam tingkat selular, salah satunya di testis sehingga menyebabkan gangguan pada testis dan penurunan produksi testosteron yang dapat menyebabkan hipogonadisme. Proses terbentuknya AGEs akan bergantung dengan rerata kadar glukosa harian pada pasien DMT2. HbA1C adalah pemeriksaan yang paling sering digunakan untuk menilai kontrol glikemik pada pasien DMT2. TUJUAN : Penelitian ini dilakukan untuk mengetahui korelasi kadar testosteron total serum dengan HbA1C pada laki – laki penderita DM Tipe 2 METODE : Subjek penelitian dikumpulkan dari pasien Poliklinik Endokrin Departemen Ilmu Penyakit Dalam RSUP Hasan Sadikin. Pemeriksaan HbA1C dilakukan dengan metode turbidimetri, sementara pemeriksaan testosteron total dilakukan dengan metode ELISA diperiksa di Instalasi Laboratorium Klinik RSUP Hasan Sadikin Bandung HASIL : Selama periode penelitian, sebanyak 70 subjek penelitian berhasil dikumpulkan dan memenuhi kriteria inklusi, didapatkan 18 dari 70 pasien memiliki penurunan kadar testosteron dengan Rerata (SB) = 424,48 (204,82) ng/mL. Hasil uji korelasi antara kedua variabel menunjukkan korelasi r = -0,619 dan nilai p <0,001, yang artinya terdapat korelasi kuat dan bermakna antara testosteron total dengan HbA1C pada pasien DMT2 KESIMPULAN : Terdapat korelasi kuat dan bermakna antara testosteron total dengan HbA1C pada subjek penderita DMT2 . Penelitian lebih lanjut dapat dilakukan secara kohort prospektif atau menggunakan pemeriksaan free testosteron Kata Kunci: Diabetes Mellitus, Glikemik, HbA1C, Testosteron","PeriodicalId":117574,"journal":{"name":"Medica Hospitalia : Journal of Clinical Medicine","volume":"93 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139210236","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

PERBEDAAN RESPON KLINIS ANTARA KEMOTERAPI KOMBINASI 5 FLUOROURASIL-PLATINUM BASED DENGAN IFOSFAMID-TAXAN-PLATINUM BASED PADA KARSINOMA NASOFARING REKUREN 复发性鼻咽癌的氟尿嘧啶-铂类联合化疗与伊福酰胺-他生-铂类联合化疗的临床反应差异

Medica Hospitalia : Journal of Clinical Medicine Pub Date : 2023-11-29 DOI: 10.36408/mhjcm.v10i3.926

Riona Sanjaya, Willy Yusmawan, D. Antono, Dwi Marliyawati, Kanti Yunika

{"title":"PERBEDAAN RESPON KLINIS ANTARA KEMOTERAPI KOMBINASI 5 FLUOROURASIL-PLATINUM BASED DENGAN IFOSFAMID-TAXAN-PLATINUM BASED PADA KARSINOMA NASOFARING REKUREN","authors":"Riona Sanjaya, Willy Yusmawan, D. Antono, Dwi Marliyawati, Kanti Yunika","doi":"10.36408/mhjcm.v10i3.926","DOIUrl":"https://doi.org/10.36408/mhjcm.v10i3.926","url":null,"abstract":"LATAR BELAKANG : Rekurensi pada KNF adalah munculnya tumor setelah mengalami remisi pasca pemberian kemoradiasi berdasarkan gejala dan pemeriksaan penunjang. Kemoterapi kombinasi pada KNF rekuren masih memberikan hasil yang baik. Kombinasi regimen yang dipakai masih bervariasi dan belum dilakukan penelitian respon klinisnya. TUJUAN : Mengetahui perbedaan respon klinis antara pemberian kombinasi 5 Fluorourasil-Platinum based (5-FU) dengan Ifosfamid-taxan-platinum based (IFO) pada KNF rekuren. METODE : . Penelitian observasional dengan desain cross-sectional menggunakan data rekam medis elektronik (RME) di poliklinik THT onkologi RSUP dr Kariadi periode Januari 2020- Januari 2022. Sampel dibagi menjadi dua kelompok masing-masing 22 subyek. Uji chi-square digunakan untuk menilai perbedaan perubahan gejala klinis, ukuran massa tumor, ukuran pembesaran KGB leher, penurunan stadium, dan pengaruh faktor perancu terhadap respon terapi pada kedua kelompok. HASIL : Jumlah penderita KNF rekuren paling banyak pada usia ≥45 tahun dan jenis kelamin laki-laki (75%). Tipe WHO 3 paling banyak ditemukan (95,5%) dan status ECOG 1 (95,5%). Tidak ada perbedaan bermakna pada pemberian kombinasi kemoterai 5-FU dengan IFO pada perubahan gejala klinis (p=0,500), perubahan ukuran tumor (p=0,347), perubahan ukuran KGB leher (p=0,164), dan penurunan stadium tumor (p=0,347). Faktor usia, jenis kelamin, jenis histopatologis, dan status performance tidak mempengaruhi respon terapi.","PeriodicalId":117574,"journal":{"name":"Medica Hospitalia : Journal of Clinical Medicine","volume":"101 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139214170","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Factors Affecting Gastric Perforation Patient Outcome with History of Arthritis and Long Term Use of NSAIDs in Dr. Kariadi Semarang Period 2020 – 2022 2020 - 2022 年期间影响有关节炎病史和长期服用非甾体抗炎药的三宝垄卡瑞迪博士医院胃穿孔患者预后的因素

Medica Hospitalia : Journal of Clinical Medicine Pub Date : 2023-11-29 DOI: 10.36408/mhjcm.v10i3.978

Leonardo Cahyo Nugroho, Ardi Fauzi, Agus Priambodo

{"title":"Factors Affecting Gastric Perforation Patient Outcome with History of Arthritis and Long Term Use of NSAIDs in Dr. Kariadi Semarang Period 2020 – 2022","authors":"Leonardo Cahyo Nugroho, Ardi Fauzi, Agus Priambodo","doi":"10.36408/mhjcm.v10i3.978","DOIUrl":"https://doi.org/10.36408/mhjcm.v10i3.978","url":null,"abstract":"Background: The incidence of gastric perforation gives a high mortality outcome. The second most common cause of gastric perforation is long-term use of NSAIDs. In cases of arthritis during the COVID-19 pandemic, a conservative therapeutic approach and administration of NSAIDs are preferred. Due to this, researchers want to know the factors affecting gastric perforation cause by NSAIDs. Method: An analytic descriptive study with a retrospective cohort study design, using electronic medical records of patients at RSUP Dr. Kariadi Semarang from January 2020 - December 2022. Data collected was in the form of demographics, diagnoses, procedures, preoperative conditions, scoring system, and outcome. Results: PULP score, one of prognostic factor, has a good level of significance compared to other scoring systems in determining the prognostic mortality of patients with gastric perforation. The combination of variables between the type of NSAIDs and the type of arthritis has a direct correlation with a positive inter-variable power of 86.7% and a significance of 0.049 on patient outcome. Conclusion: NSAIDs pose a risk of gastric perforation in long-term use. tNSAIDs carry a higher risk inducing gastric perforation than selective NSAIDs.","PeriodicalId":117574,"journal":{"name":"Medica Hospitalia : Journal of Clinical Medicine","volume":"45 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139214203","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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