ERJ Open ResearchPub Date : 2024-07-29eCollection Date: 2024-07-01DOI: 10.1183/23120541.00406-2024
Mengru Zhang, Dominic L Sykes
{"title":"Coughing our guts up: how do we diagnose reflux cough?","authors":"Mengru Zhang, Dominic L Sykes","doi":"10.1183/23120541.00406-2024","DOIUrl":"10.1183/23120541.00406-2024","url":null,"abstract":"<p><p><b>Should Peptest be routinely used in a cough clinic? The answer is yes, but only as part of more intricate workup in which discovering the nature of the reflux is as important as identifying its presence.</b> https://bit.ly/3QkbChb.</p>","PeriodicalId":11739,"journal":{"name":"ERJ Open Research","volume":null,"pages":null},"PeriodicalIF":4.3,"publicationDate":"2024-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11284586/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141792242","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ERJ Open ResearchPub Date : 2024-07-29eCollection Date: 2024-07-01DOI: 10.1183/23120541.50534-2020
{"title":"Erratum: \"Azithromycin for sarcoidosis cough: an open-label exploratory clinical trial\". Simon D. Fraser, Susannah Thackray-Nocera, Marica Shepherd, Rachel Flockton, Caroline Wright, Wayne Sheedy, Kayleigh Brindle, Alyn H. Morice, Paul M. Kaye, Michael G. Crooks and Simon P. Hart. <i>ERJ Open Res</i> 2020; 6: 00534-2020.","authors":"","doi":"10.1183/23120541.50534-2020","DOIUrl":"https://doi.org/10.1183/23120541.50534-2020","url":null,"abstract":"<p><p>[This corrects the article DOI: 10.1183/23120541.00821-2023.].</p>","PeriodicalId":11739,"journal":{"name":"ERJ Open Research","volume":null,"pages":null},"PeriodicalIF":4.3,"publicationDate":"2024-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11284596/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141792243","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ERJ Open ResearchPub Date : 2024-07-29eCollection Date: 2024-07-01DOI: 10.1183/23120541.00202-2024
Sebastian Riemann, Johnmary T Arinze, Andrei Malinovschi, Guy G Brusselle
{"title":"Need for sex-stratified reference values for exhaled nitric oxide as biomarker in chronic cough.","authors":"Sebastian Riemann, Johnmary T Arinze, Andrei Malinovschi, Guy G Brusselle","doi":"10.1183/23120541.00202-2024","DOIUrl":"10.1183/23120541.00202-2024","url":null,"abstract":"<p><p><b>The implementation of exhaled nitric oxide fraction (<i>F</i> <sub>ENO</sub>) as a biomarker in patients with chronic cough requires sex-stratified <i>F</i> <sub>ENO</sub> reference values in general and sex-stratified cut-off levels in the management of unexplained chronic cough</b> https://bit.ly/3JHi0vb.</p>","PeriodicalId":11739,"journal":{"name":"ERJ Open Research","volume":null,"pages":null},"PeriodicalIF":4.3,"publicationDate":"2024-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11284590/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141792244","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ERJ Open ResearchPub Date : 2024-07-22eCollection Date: 2024-07-01DOI: 10.1183/23120541.00305-2024
Angela T Burge, Annemarie L Lee
{"title":"Get a move on: physical (in)activity in people with obstructive airway disease.","authors":"Angela T Burge, Annemarie L Lee","doi":"10.1183/23120541.00305-2024","DOIUrl":"10.1183/23120541.00305-2024","url":null,"abstract":"<p><p><b>A study extended the \"can do, do do\" concept in people with obstructive airways disease to demonstrate different clinical and movement behaviour characteristics based on quadrant classification, and proposed a treatable traits approach to management</b> https://bit.ly/4cOGlN5.</p>","PeriodicalId":11739,"journal":{"name":"ERJ Open Research","volume":null,"pages":null},"PeriodicalIF":4.3,"publicationDate":"2024-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11261376/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141747784","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Time to negative conversion and cardiopulmonary performance in athletes with COVID-19.","authors":"Pasquale Mone, Leonardo Bencivenga, Gaetano Santulli, Giuseppe Rengo, Germano Guerra, Klara Komici","doi":"10.1183/23120541.00090-2024","DOIUrl":"10.1183/23120541.00090-2024","url":null,"abstract":"<p><p><b>Athletes with longer time to negative conversion for COVID-19 do not present reduction of exercise capacity. However, respiratory and ventilatory parameters are modified.</b> https://bit.ly/3TMdrFL.</p>","PeriodicalId":11739,"journal":{"name":"ERJ Open Research","volume":null,"pages":null},"PeriodicalIF":4.3,"publicationDate":"2024-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11261377/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141747785","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ERJ Open ResearchPub Date : 2024-07-15eCollection Date: 2024-07-01DOI: 10.1183/23120541.00240-2024
Sharyn A Roodenburg, Jorine E Hartman, Ilse A Eichhorn, Dirk-Jan Slebos, Simon D Pouwels
{"title":"Low serum double-stranded DNA levels are associated with higher survival rates in severe COPD patients.","authors":"Sharyn A Roodenburg, Jorine E Hartman, Ilse A Eichhorn, Dirk-Jan Slebos, Simon D Pouwels","doi":"10.1183/23120541.00240-2024","DOIUrl":"10.1183/23120541.00240-2024","url":null,"abstract":"<p><strong>Introduction: </strong>Damage-associated molecular patterns (DAMPs) are endogenous danger signals that alert and activate the immune system upon cellular damage or death. It has previously been shown that DAMP release is increased in patients with COPD, leading to higher levels in extracellular fluids such as serum. In the current study we investigated whether the serum levels of DAMPs were associated with survival rates in COPD patients.</p><p><strong>Methods: </strong>A panel of seven DAMPs, consisting of HMGB1, fibrinogen, α-defensin, heat shock protein 70, S100A8, galectin-9 and double-stranded DNA (dsDNA), was measured in serum of 949 severe COPD patients. Maximally selected rank statistics was used to define cut-off values and a Cox proportional hazards model was used to evaluate the effect of high or low DAMP levels on 4-year survival. For DAMPs that were found to affect survival significantly, baseline characteristics were compared between the two DAMP groups.</p><p><strong>Results: </strong>Out of the seven DAMPs, only dsDNA was significantly associated with 4-year survival. Patients with elevated serum level of dsDNA had higher 4-year mortality rates, lower FEV<sub>1</sub> % predicted values and higher emphysema scores.</p><p><strong>Discussion: </strong>In conclusion, in a clinical cohort of 949 patients with moderate-to-severe COPD, elevated serum levels of dsDNA were associated with a higher risk of death. This study further illustrates the potential role of circulating DAMPs, such as dsDNA, in the progression of COPD. Together, the results of this study suggest that levels of circulating dsDNA might serve as an additional prognostic biomarker for survival in COPD patients.</p>","PeriodicalId":11739,"journal":{"name":"ERJ Open Research","volume":null,"pages":null},"PeriodicalIF":4.3,"publicationDate":"2024-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11247366/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141619652","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ERJ Open ResearchPub Date : 2024-07-08eCollection Date: 2024-07-01DOI: 10.1183/23120541.00294-2024
Brian G Oliver, Paul S Foster
{"title":"To burn or not to burn: similar effects of different types of prenatal tobacco exposure on infant lung function.","authors":"Brian G Oliver, Paul S Foster","doi":"10.1183/23120541.00294-2024","DOIUrl":"10.1183/23120541.00294-2024","url":null,"abstract":"<p><p><b>The first study to describe the harmful effects of snus on the unborn infant provides evidence to help clinicians and mothers collectively to make an informed choice about quitting the use of snus before planning pregnancies</b> https://bit.ly/3vJnBxW.</p>","PeriodicalId":11739,"journal":{"name":"ERJ Open Research","volume":null,"pages":null},"PeriodicalIF":4.3,"publicationDate":"2024-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11228605/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141558351","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Height seems to be the only variable that determines lung oscillometry indices.","authors":"Deesha Ghorpade, Sujata Chauthmal, Ruby Swami, Sundeep Salvi","doi":"10.1183/23120541.00106-2024","DOIUrl":"10.1183/23120541.00106-2024","url":null,"abstract":"<p><p><b>Oscillometry presents four distinct advantages over spirometry</b> https://bit.ly/49LNPyh.</p>","PeriodicalId":11739,"journal":{"name":"ERJ Open Research","volume":null,"pages":null},"PeriodicalIF":4.3,"publicationDate":"2024-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11228603/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141560906","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ERJ Open ResearchPub Date : 2024-07-08eCollection Date: 2024-07-01DOI: 10.1183/23120541.00289-2024
Laura Gochicoa-Rangel, David Martínez-Briseño, Mario H Vargas
{"title":"Reply to: Height seems to be the only variable that determines lung oscillometry indices.","authors":"Laura Gochicoa-Rangel, David Martínez-Briseño, Mario H Vargas","doi":"10.1183/23120541.00289-2024","DOIUrl":"10.1183/23120541.00289-2024","url":null,"abstract":"<p><p><b>Age, sex and BMI, as well as height, should be used in IOS reference equations</b> https://bit.ly/3VMUMLz.</p>","PeriodicalId":11739,"journal":{"name":"ERJ Open Research","volume":null,"pages":null},"PeriodicalIF":4.3,"publicationDate":"2024-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11228607/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141560907","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ERJ Open ResearchPub Date : 2024-06-17eCollection Date: 2024-05-01DOI: 10.1183/23120541.00059-2024
Amy Gilmour, Chloe Hughes, Yan Hui Giam, Rebecca C Hull, Thomas Pembridge, Hani Abo-Leyah, A A Roger Thompson, Alison M Condliffe, Amelia Shoemark, James D Chalmers, Merete B Long
{"title":"A serum calprotectin lateral flow test as an inflammatory and prognostic marker in acute lung infection: a prospective observational study.","authors":"Amy Gilmour, Chloe Hughes, Yan Hui Giam, Rebecca C Hull, Thomas Pembridge, Hani Abo-Leyah, A A Roger Thompson, Alison M Condliffe, Amelia Shoemark, James D Chalmers, Merete B Long","doi":"10.1183/23120541.00059-2024","DOIUrl":"10.1183/23120541.00059-2024","url":null,"abstract":"<p><p><b>A rapid, quantitative serum S100A8/A9 (calprotectin) lateral flow test in combination with clinical status predicted outcomes in people hospitalised with COVID-19 and associated with a patient cluster driven by markers of neutrophil activation</b> https://bit.ly/48e1BIv.</p>","PeriodicalId":11739,"journal":{"name":"ERJ Open Research","volume":null,"pages":null},"PeriodicalIF":4.6,"publicationDate":"2024-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11181086/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141418368","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}