Enfermedades infecciosas y microbiologia clinica最新文献

{"title":"Dalbavancina como tratamiento antibiótico de consolidación en endocarditis infecciosa, infección de dispositivos de estimulación cardiaca y bacteriemia: experiencia clínica de 7 años","authors":"Alejandro Salinas-Botrán ,&nbsp;Carmen Olmos-Blanco ,&nbsp;David Fernández de Velasco-Pérez ,&nbsp;Alicia Guzmán-Carreras ,&nbsp;Alejandro Morales-Rosas ,&nbsp;Daniel Gómez-Ramírez","doi":"10.1016/j.eimc.2024.02.010","DOIUrl":"10.1016/j.eimc.2024.02.010","url":null,"abstract":"<div><h3>Introduction</h3><div>Dalbavancin (DBV), a novel lipoglycopeptide with activity against Gram-positive bacterial infections, is approved for the treatment of acute bacterial skin and skin structure infections. It has linear dose-related pharmacokinetics allowing a prolonged interval between doses. It would be a good option for the treatment of patients with Gram-positive cardiovascular infections.</div></div><div><h3>Material and methods</h3><div>Retrospective analysis of patients with cardiovascular infection (bacteremia, implantable electronic device infection and infective endocarditis [IE]) treated with DBV at Hospital Clínico San Carlos (Madrid) for 7 years (2016-2022). Patients were divided into 2 study groups: 1) IE, and 2) bacteremia. Epidemiological, clinical, microbiological and therapeutic data were analyzed.</div></div><div><h3>Results</h3><div>A total of 25 patients were treated with DBV for cardiovascular infection. IE was the most common indication (68%), followed by bacteremia (32%) with male predominance in both groups (64 vs. 62%) and median age of 67,7 and 57,5 years, respectively. Hundred percent of blood cultures were positive to Gram-positive microorganisms (<em>Staphylococcus</em> spp., <em>Streptococcus</em> spp. or <em>Enterococcus</em> spp.) in both study groups. Previously to DBV, all patients received other antibiotic therapy, both in the group of IE (median: 80 days) as in bacteremia (14,8 days). The main reason for the administration of DBV was to continue intravenous antimicrobial therapy outside the hospital in both the EI group (n<!--> <!-->=<!--> <!-->15) and the bacteremia group (n<!--> <!-->=<!--> <!-->8). DBV was used as consolidation therapy in a once- or twice-weekly regimen. Microbiological and clinical successes were reached in 84% of cases (n<!--> <!-->=<!--> <!-->21), 76,4% in IE group and 100% in bacteremia group. No patient documented adverse effects during long-term DBV treatment.</div></div><div><h3>Conclusion</h3><div>DBV is an effective and safety treatment as consolidation antibiotic therapy in IE and bacteremia produced by Gram-positive microorganisms.</div></div>","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":"43 2","pages":"Pages 71-79"},"PeriodicalIF":2.6,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140400211","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Unusually high incidence of pneumonia in Navarre, Spain, 2023–2024","authors":"Camino Trobajo-Sanmartín ,&nbsp;María Eugenia Portillo ,&nbsp;Ana Navascués ,&nbsp;Iván Martínez-Baz ,&nbsp;Carmen Ezpeleta ,&nbsp;Jesús Castilla","doi":"10.1016/j.eimc.2024.08.008","DOIUrl":"10.1016/j.eimc.2024.08.008","url":null,"abstract":"<div><h3>Objective</h3><div>To assess the pneumonia incidence in Navarre, Spain, in the 2023–2024 season.</div></div><div><h3>Methods</h3><div>Using electronic medical records, we evaluated the incidence of clinical pneumonia, positive pneumococcal antigen cases and <em>Mycoplasma pneumoniae</em> positive PCR cases by age groups from 2017–2018 to 2023–2024 season.</div></div><div><h3>Results</h3><div>Compared to the average of the 2017–2018 and 2018–2019 seasons, in the 2023–2024 season, pneumonia incidence rate increased by 73% overall and multiplied by 4.43 in the age group of 5–14 years. The rate of confirmed pneumococcal pneumonia increased by 63%, and that of <em>M. pneumoniae</em> multiplied by 19.</div></div><div><h3>Conclusion</h3><div>Pneumonia incidence was unusually high in all ages in the 2023–2024 season and was related to upsurges in pneumococcal and <em>Mycoplasma</em> diseases.</div></div>","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":"43 2","pages":"Pages 93-96"},"PeriodicalIF":2.6,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143166762","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Erythema induratum of Bazin—A cutaneous manifestation of tuberculosis","authors":"Maria Ana Quadros Flores ,&nbsp;Gustavo Almeida Silva ,&nbsp;Paulo Filipe ,&nbsp;Sérgio Eduardo Paulo","doi":"10.1016/j.eimc.2024.06.006","DOIUrl":"10.1016/j.eimc.2024.06.006","url":null,"abstract":"","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":"43 2","pages":"Pages 110-112"},"PeriodicalIF":2.6,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141851985","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of UV-C disinfection and copper plating on healthcare-associated infections in a NICU with high ESBL infections","authors":"Daniela de la Rosa-Zamboni,&nbsp;Mónica Villa-Guillén,&nbsp;Anaíd Bustos-Hamdan,&nbsp;María Isabel Rosas-Mateos,&nbsp;Marisol Medina-Pelcastre,&nbsp;Margarita Torres-García,&nbsp;María Isabel Franco-Hernández,&nbsp;María del Carmen Castellanos-Cruz,&nbsp;Israel Parra-Ortega,&nbsp;Edmedt Fest-Parra,&nbsp;María Citlalli Casillas-Casillas,&nbsp;Ana Carmen Guerrero-Díaz","doi":"10.1016/j.eimc.2024.02.009","DOIUrl":"10.1016/j.eimc.2024.02.009","url":null,"abstract":"<div><h3>Introduction</h3><div>Healthcare-associated infections (HCAIs) in neonates are frequent and highly lethal, in particular those caused by extended spectrum beta-lactamase (ESBL) producing bacteria. We evaluated the beneficial effects of ultraviolet C (UV-C) disinfection and copper adhesive plating on HCAIs in the Neonatal Intensive Care Unit (NICU) of a third level paediatric hospital in Mexico City, both in combination of hand-hygiene (HH) and prevention bundles.</div></div><div><h3>Methods</h3><div>All NICU patients were included. There were 4 periods (P): P1: HH monitoring and prevention bundles; P2: P1<!--> <!-->+<!--> <!-->UV-C disinfection; P3: P2<!--> <!-->+<!--> <!-->Copper adhesive plating on frequent-contact surfaces and P4: Monitoring of P3 actions.</div></div><div><h3>Results</h3><div>552 neonates were monitored during 15,467 patient days (PD). HCAI rates decreased from 11.03/1000 PD in P1 to 5.35/1000 PD in P4 (<em>p</em> <!-->=<!--> <!-->0.006). HCAIs with bacterial isolates dropped from 5.39/1000 PD in PI to 1.79/1000 PD in P4 (<em>p</em> <!-->=<!--> <!-->0.011). UV-C and copper were associated with significant HCAI prevention (RR 0.49, CI_95% 0.30–0.81, <em>p</em> <!-->=<!--> <!-->0.005) and with lesser HCAIs with bacterial isolates (RR 0.33, CI_95% 0.14–0.77, <em>p</em> <!-->=<!--> <!-->0.011).</div></div><div><h3>Conclusions</h3><div>Copper adhesive plating combined with UV-C disinfection were associated with a drop in HCAI rates and with the elimination of ESBL-caused HCAIs. Hence, we propose that these strategies be considered in MDRO proliferation preventions.</div></div>","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":"43 2","pages":"Pages 64-70"},"PeriodicalIF":2.6,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140407999","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dalbavancin: A new milestone in the treatment of Gram-positive infections","authors":"Arístides de Alarcón González","doi":"10.1016/j.eimc.2024.12.004","DOIUrl":"10.1016/j.eimc.2024.12.004","url":null,"abstract":"","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":"43 2","pages":"Pages 61-63"},"PeriodicalIF":2.6,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143166761","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"19 years of VINCat program: Exploring the past, present, and future of infection prevention in Catalonia","authors":"Miquel Pujol ,&nbsp;Enric Limón","doi":"10.1016/j.eimc.2024.12.021","DOIUrl":"10.1016/j.eimc.2024.12.021","url":null,"abstract":"","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":"43 ","pages":"Pages S1-S2"},"PeriodicalIF":2.6,"publicationDate":"2025-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143852125","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Surveillance of catheter-related bacteremia in VINCat program","authors":"Oriol Gasch ,&nbsp;Alexander Almendral ,&nbsp;Marta Andrés ,&nbsp;Jordi Càmara ,&nbsp;Dolors Domenech ,&nbsp;Xavier Garcia-Alarcon ,&nbsp;M. José García-Quesada ,&nbsp;Emilio Jiménez-Martínez ,&nbsp;Anna Marrón ,&nbsp;Encarnación Moreno ,&nbsp;Virginia Pomar ,&nbsp;Montserrat Vaqué ,&nbsp;Enric Limón ,&nbsp;Miquel Pujol ,&nbsp;on behalf of VINCat Programme","doi":"10.1016/j.eimc.2024.12.001","DOIUrl":"10.1016/j.eimc.2024.12.001","url":null,"abstract":"<div><h3>Background</h3><div>Catheter-related bacteremia (CRB) is one of the most frequent infections acquired during hospitalization. We summarize the results of CRB surveillance conducted by the Catalan Program of Surveillance of Nosocomial Infections (VINCat) over the past fifteen years.</div></div><div><h3>Methods</h3><div>All episodes of hospital-acquired CRB diagnosed in the 55 Catalan hospitals participating in the VINCat program (2008–2023) were recorded. Annual incidence rates per 1000 patient-days were calculated. Analyses were stratified into three relevant five-year periods: 2008–2012, 2013–2017, and 2018–2022. Incidence rate ratios (IRRs) were used to compare infection rates.</div></div><div><h3>Results</h3><div>During the study period, 10,212 episodes of nosocomial CRB were diagnosed. The global incidence rate was 0.21 episodes per 1000 patient-days (intensive care units (ICUs): 1.13; medical wards: 0.16; surgical wards: 0.15). Gram-positive bacteria caused 68.3% of the episodes. The incidence rate of CRB acquired in ICUs and that of CRB associated with central venous catheters decreased during the study period, while episodes associated with peripheral venous catheters (PVCs) and peripherally-inserted central venous catheters (PICVCs) significantly increased (<em>p</em> <!-->&lt;<!--> <!-->0.001).</div></div><div><h3>Conclusions</h3><div>The current study underscores the necessity for interventional programs targeting PVCs, particularly in non-ICU wards.</div></div>","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":"43 ","pages":"Pages S19-S27"},"PeriodicalIF":2.6,"publicationDate":"2025-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143852128","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Trends in point-prevalence surveys of healthcare-associated infections in acute care hospitals from the VINCat program in Catalonia, Spain (2008–2022)","authors":"Irma Casas ,&nbsp;Jose Ángel Rodrigo ,&nbsp;Esther Rodríguez ,&nbsp;Dina Reina ,&nbsp;Dolors Ramirez ,&nbsp;Alexander Almendral ,&nbsp;Enric Limón ,&nbsp;Miquel Pujol ,&nbsp;on behalf of VINCat Programme Acute Care Hospital Prevalence Point Survey group","doi":"10.1016/j.eimc.2024.12.002","DOIUrl":"10.1016/j.eimc.2024.12.002","url":null,"abstract":"<div><h3>Introduction</h3><div>Point prevalence surveys (PPS) offer valuable insights into the burden of healthcare-associated infections (HAIs) and antibiotic utilization. Our objective was to analyze trends of HAIs, medical device use, and antibiotic administration among hospitalized adult patients from 2008 to 2022, drawing on data from the VINCat Program in Catalonia, Spain.</div></div><div><h3>Methods</h3><div>The study compares aggregated data from PPS carried out over three 5-year periods (2008–2012, 2013–2017, and 2018–2022) gathered in a one-day survey carried out in May of each calendar year. Trained infection control personnel collected demographic and clinical data and information on device use and antibiotic administration. Criteria from the ECDC were used to define active HAI.</div></div><div><h3>Results</h3><div>Surveys were conducted at 56 acute care hospitals and included 59,454 patients: 14,914 (period 1), 19,916 (period 2) and 24,624 (period 3). Overall, 3986 patients (6.7%, 95% confidence interval: 6.5–6.9) had one or more HAIs. The trend of HAIs showed a U-shape, falling overall since 2008 but rising during the COVID-19 pandemic. Although there was a significant increase in the use of invasive devices, surgical site infections (SSI) were the most frequently reported HAIs across the three periods. The prevalence of antimicrobial therapy exhibited a significant rise from 33.3% of patients during period 1 to 39.2% in period 3.</div></div><div><h3>Conclusion</h3><div>Although there was an overall downward trend in HAIs during the study period, there was also a significant increase in antibiotic consumption. The data showed that SSI was the most prevalent HAI. This information was used to reinforce prevention activities.</div></div>","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":"43 ","pages":"Pages S3-S10"},"PeriodicalIF":2.6,"publicationDate":"2025-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143852126","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comprehensive surveillance of antimicrobial susceptibility across adult and pediatric populations in Catalonia: Insights from community, hospital, and long-term care facility settings","authors":"Nieves Larrosa ,&nbsp;Montserrat Giménez ,&nbsp;Mónica Ballestero-Téllez ,&nbsp;Sergi Hernández ,&nbsp;Alexander Almendral ,&nbsp;Juan P. Horcajada ,&nbsp;Susana Melendo ,&nbsp;M Pilar García ,&nbsp;Albert Boada ,&nbsp;Enric Limón ,&nbsp;Miquel Pujol ,&nbsp;on behalf of the microbiologists of the participating laboratories in VINCat-PROA","doi":"10.1016/j.eimc.2024.12.003","DOIUrl":"10.1016/j.eimc.2024.12.003","url":null,"abstract":"<div><h3>Background</h3><div>This study presents comprehensive data on antimicrobial susceptibility across healthcare settings and age groups in Catalonia, Spain.</div></div><div><h3>Methods</h3><div>Susceptibility data were collected from 37 microbiology laboratories between 2020 and 2022 for community-acquired infections (CAIs), and 2021 and 2022 for hospital and long-term care facilities (LTCFs). Susceptibility was calculated based on the proportion of susceptible strains among the total strains.</div></div><div><h3>Results</h3><div>Pediatrics: Community-acquired infections (CAIs): in urinary tract infections (UTIs), extended-spectrum beta-lactamase production (ESBL-P) <em>Escherichia coli</em> was 3.8%. <em>Streptococcus pneumoniae</em> was highly susceptible to penicillins (97.5%). Community-acquired methicillin-resistant <em>Staphylococcus aureus</em> was 6.8%. Hospital-acquired infections (HAIs): ESBL-P in <em>E. coli</em> and <em>Klebsiella pneumoniae</em> were 6.7% and 9.4%. Carbapenem resistance in <em>Enterobacter cloacae</em> complex was less than 1%. Extremely drug-resistant <em>Pseudomonas aeruginosa</em> was 1.6%.</div></div><div><h3>Adults</h3><div>CAIs: In UTIs, <em>E. coli</em> showed high susceptibility to fosfomycin (&gt;95%) and 9% of ESBL-P. In respiratory tract infections, <em>Streptococcus pyogenes</em> exhibited reduced susceptibility to macrolides (67%) and clindamycin (75.1%), while <em>Haemophilus influenzae</em> and <em>S. pneumoniae</em> remained susceptible to penicillins (78% and 96%). HAIs: <em>E. coli</em> showed 12.8% of ESBL-P and <em>K. pneumoniae</em> 20%. Carbapenem resistance was mainly identified in <em>E. cloacae</em> (2.8%) and <em>K. pneumoniae</em> (2.2%). <em>P. aeruginosa</em> showed high susceptibility to meropenem (87%). Methicillin-resistance was detected in 22% of <em>S. aureus</em>.</div><div>Long-term care facilities (LTCFs): <em>E. coli</em> causing UTI was highly susceptible to carbapenems (99%), nitrofurantoin (96%), and fosfomycin (93%) with 25.8% of ESBL-P. <em>K. pneumoniae</em> showed 40% ESBL-P and 2.9% of carbapenem resistance. <em>P. aeruginosa</em> exhibited decreased susceptibility to quinolones (69.5%) and highly susceptibility to meropenem (88.5%).</div></div><div><h3>Conclusion</h3><div>The data underscore the necessity of stratified susceptibility reports by setting, type of infection, and age.</div></div>","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":"43 ","pages":"Pages S80-S89"},"PeriodicalIF":2.6,"publicationDate":"2025-01-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143852045","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Trends in point-prevalence studies of healthcare associated infections in long-term care facilities: A nationwide surveillance program in Catalonia, Spain (2013–2022)","authors":"M.ª Pilar Garcia ,&nbsp;Olga Vázquez ,&nbsp;Julio Duran ,&nbsp;Juan Pablo Horcajada ,&nbsp;Alexander Almendral ,&nbsp;Rosario Porrón ,&nbsp;Enric Limón ,&nbsp;Miquel Pujol ,&nbsp;on behalf of VINCat Programme Long-Term Care Facilities Prevalence Point Survey group","doi":"10.1016/j.eimc.2024.11.003","DOIUrl":"10.1016/j.eimc.2024.11.003","url":null,"abstract":"<div><h3>Introduction</h3><div>From 2013 to 2022, annual point-prevalence studies (PPS) of healthcare-associated infections (HAIs) were conducted in 97 long-term care facilities (LTCF) within the VINCat Program in Catalonia, Spain. The objective was to analyze trends in HAIs and antibiotic use to evaluate the burden of HAIs in this setting.</div></div><div><h3>Methods</h3><div>We compare PPS data from two 5-year periods. Period 1 (2013–2017) involving 50,378 residents and period 2 (2018–2022) involving 65,997 residents. Variables included demographic characteristics, patient conditions, medical devices on the day of PPS and recent surgery. Source of HAI, causative microorganisms, antibiotics and indication were recorded. HAIs were defined according to ECDC criteria.</div></div><div><h3>Results</h3><div>A total of 116,375 residents were included, median age of 82 years (range: 73–88), 56.7% female. Although severe dependency was more common in period 1, the presence of vascular and urinary catheters increased in period 2. Overall, 9943 (8.5%) residents had one or more HAIs. The HAI prevalence rate significantly decreased from 9.3% in period 1 to 8% in period 2, being urinary tract infections the most prevalent HAI in both periods, followed by respiratory tract infections. <em>Escherichia coli</em> was the most frequently identified microorganism. No significant differences in the prevalence of antibiotic use between periods (11.8 vs 12.1 respectively) were found, although there was a shift toward more targeted prescriptions.</div></div><div><h3>Conclusion</h3><div>Despite a significant reduction over the study period, the prevalence of HAIs remains high in LTCFs of Catalonia, affecting 8% of residents. Implementation of infection prevention and control interventions are highly required.</div></div>","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":"43 ","pages":"Pages S11-S18"},"PeriodicalIF":2.6,"publicationDate":"2025-01-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143852127","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}