Enfermedades infecciosas y microbiologia clinica最新文献_第7页

Investigating outbreaks in neonatal intensive care units: A crucial battle in the cradle of care 调查新生儿重症监护室的疫情爆发：护理摇篮中的一场关键战役

IF 2.5 4区医学

Enfermedades infecciosas y microbiologia clinica Pub Date : 2024-06-01 DOI: 10.1016/j.eimc.2024.03.004

Esther Calbo , Laura Gisbert , Maria López-Sánchez

引用次数: 0

Análisis transversal de una cohorte de personas de más de 65 años que viven con VIH 对 65 岁以上艾滋病毒感染者队列的横断面分析

IF 2.5 4区医学

Enfermedades infecciosas y microbiologia clinica Pub Date : 2024-06-01 DOI: 10.1016/j.eimc.2024.01.008

Iván Fernández-Castro, Clara Casar-Cocheteux, Hadrian Pernas-Pardavila, Elena Losada-Arias, Antonio Antela

{"title":"Análisis transversal de una cohorte de personas de más de 65 años que viven con VIH","authors":"Iván Fernández-Castro, Clara Casar-Cocheteux, Hadrian Pernas-Pardavila, Elena Losada-Arias, Antonio Antela","doi":"10.1016/j.eimc.2024.01.008","DOIUrl":"10.1016/j.eimc.2024.01.008","url":null,"abstract":"<div><h3>Introduction</h3><p>This study aims to describe and analyze the characteristics of aged people who are living with HIV (APHIV) and evaluate their association on the comorbidities they currently have.</p></div><div><h3>Methods</h3><p>Cross-sectional analysis of APHIV under active follow-up at the Infectious Diseases Unit of the University Clinical Hospital of Santiago de Compostela. Demographic and clinical data were analyzed, along with their association with the development of comorbidities in this population. A correlation and multiple linear regression analysis were performed for this purpose.</p></div><div><h3>Results</h3><p>Eighty-five APHIV, 65 males and 20 females, with an average age of 69 years (IQR: 8) and a duration of living with HIV of 17 years (SD: 7), were studied. 41% of them had their initial diagnosis with AIDS. The most common comorbidities are hypertension and dyslipidemia in 55% and 52%, respectively. 40% of APHIV take at least 5 medications. 35% have received more than 5 lines of antiretroviral treatment. At the time of analysis, all APHIV have an undetectable viral load. No significant association was observed between the number of comorbidities and various characteristics of APHIV; however, a weak correlation was noted among age, the cumulative number of antiretroviral treatments received throughout their lives, and the number of comorbidities.</p></div><div><h3>Conclusions</h3><p>This analysis highlights the substantial burden of comorbidities and polypharmacy experienced by APHIV. Further studies are needed to better understand the characteristics and variables influencing their development.</p></div>","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":"42 6","pages":"Pages 317-320"},"PeriodicalIF":2.5,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139988205","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Brote nosocomial causado por Serratia marcescens en una unidad de cuidados intensivos neonatal de un hospital regional. Análisis y propuestas de mejora 一家地区医院的新生儿重症监护室爆发了由肉豆蔻沙雷氏菌引起的医院内感染。分析和改进建议

IF 2.5 4区医学

Enfermedades infecciosas y microbiologia clinica Pub Date : 2024-06-01 DOI: 10.1016/j.eimc.2023.04.001

María Liébana-Rodríguez , Inés Portillo-Calderón , María Amelia Fernández-Sierra , Mercedes Delgado-Valverde , Lina Martín-Hita , José Gutiérrez-Fernández

{"title":"Brote nosocomial causado por Serratia marcescens en una unidad de cuidados intensivos neonatal de un hospital regional. Análisis y propuestas de mejora","authors":"María Liébana-Rodríguez , Inés Portillo-Calderón , María Amelia Fernández-Sierra , Mercedes Delgado-Valverde , Lina Martín-Hita , José Gutiérrez-Fernández","doi":"10.1016/j.eimc.2023.04.001","DOIUrl":"10.1016/j.eimc.2023.04.001","url":null,"abstract":"<div><h3>Objectives</h3><p><em>Serratia marcescens</em> may cause nosocomial outbreaks in neonatal intensive care units. We describe an outbreak of <em>Serratia marcescens</em> in a neonatal intensive care unit and propose additional prevention and control recommendations.</p></div><div><h3>Methods</h3><p>Between March 2019 and January 2020, samples were taken from patients in the neonatal intensive care unit (rectal, pharyngeal, axillary and other locations) and from 15 taps and their sinks. Control measures were implemented including thorough cleaning of incubators, health education to staff and neonates’ relatives, and use of single-dose containers. PFGE was performed in 19 isolates from patients and in 5 environmental samples.</p></div><div><h3>Results</h3><p>From the first case in March 2019 to the detection of the outbreak, a month elapsed. Finally, 20 patients were infected and 5 colonized. Eighty percent of infected neonates had conjunctivitis, 25% bacteremia, 15% pneumonia, 5% wound infection, and 5% urinary tract infection. Six neonates had 2 foci of infection. Among the 19 isolates studied, 18 presented the same pulsotype and only one of the isolates from the sinkhole showed a clonal relationship with those of the outbreak. Initial measures established were ineffective to control the outbreak and were implemented with exhaustive cleaning, use of individual eye drops, environmental sampling and changing sinks.</p></div><div><h3>Conclusion</h3><p>This outbreak presented a high number of neonates affected due to its late detection and torpid evolution. The microorganisms isolated from the neonates were related to an environmental isolate. Additional prevention and control measures are proposed, including routine weekly microbiological sampling.</p></div>","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":"42 6","pages":"Pages 286-293"},"PeriodicalIF":2.5,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116411222","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A case of unresolved skin lesion in a cobbler 一个鞋匠身上未治愈的皮损病例

IF 2.5 4区医学

Enfermedades infecciosas y microbiologia clinica Pub Date : 2024-06-01 DOI: 10.1016/j.eimc.2023.12.002

Ali Mert , Abdurrahman Kaya , Sibel Yildiz Kaya

引用次数: 0

Celulitis craneo-facial con pericondritis y otitis externa profesional, a propósito de un caso 颅面蜂窝织炎伴软骨周炎和职业性外耳道炎，病例报告

IF 2.5 4区医学

Enfermedades infecciosas y microbiologia clinica Pub Date : 2024-06-01 DOI: 10.1016/j.eimc.2024.02.008

Eloy Sempere Moreno, Santos Ibáñez Barceló, Marta Montero Alonso

引用次数: 0

Espiroquetosis intestinal humana como entidad asociada a infecciones de transmisión sexual 作为性传播感染相关实体的人类肠道螺旋体病

IF 2.5 4区医学

Enfermedades infecciosas y microbiologia clinica Pub Date : 2024-05-01 DOI: 10.1016/j.eimc.2023.03.001

Alejandro De Gea-Grela , Alfredo Maldonado-Barrueco , Clara Cabañuz , Mariana Díaz-Almiron , Alicia Rico , Guillermo Ruíz-Carrascoso , Maria Elena Palacios , Eduardo Martín-Arranz , Raquel Escudero-Nieto , José I Bernardino

{"title":"Espiroquetosis intestinal humana como entidad asociada a infecciones de transmisión sexual","authors":"Alejandro De Gea-Grela , Alfredo Maldonado-Barrueco , Clara Cabañuz , Mariana Díaz-Almiron , Alicia Rico , Guillermo Ruíz-Carrascoso , Maria Elena Palacios , Eduardo Martín-Arranz , Raquel Escudero-Nieto , José I Bernardino","doi":"10.1016/j.eimc.2023.03.001","DOIUrl":"10.1016/j.eimc.2023.03.001","url":null,"abstract":"<div><h3>Introduction</h3><p>Human intestinal spirochetosis (HIE) is a poorly studied clinical entity with variable clinical manifestations. However, in recent years it has gained special relevance because an increasing number of cases have been described in people living with HIV (PWH) and in patients with a history of sexually transmitted infections (STI) or immunosuppression.</p></div><div><h3>Methods</h3><p>retrospective review of all HIE cases identified in a tertiary level hospital (Hospital Universitario la Paz, Madrid) between 2014-2021.</p></div><div><h3>Results</h3><p>36 cases of HIE were identified. Most cases corresponded to males (94%) with a median age of 45 years. 10 patients (29.4%) were PWH and 20 (56%) were men who had sex with men. Although the clinical manifestations were very heterogeneous, the most frequent was chronic diarrhea (47%), and up to 25% of the subjects had clinical proctitis. 39% percent of patients had been diagnosed with an STI in the previous two years, this characteristic being more frequent in PWH (90% vs 28%; p < 0.01) than in patients without HIV infection. The STI most frequently associated with a diagnosis of HIE was syphilis (31%).</p></div><div><h3>Conclusión</h3><p>HIE is frequently diagnosed with other STIs and affects mostly men who have sex with men, which supports that this entity could be considered as a new STI.</p></div>","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":"42 5","pages":"Pages 231-235"},"PeriodicalIF":2.5,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115242072","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Low rate of vaccination and risk of incident hepatitis A among HIV-infected men who have sex with men in Seville, Southern Spain 在西班牙南部塞维利亚，受艾滋病毒感染的男男性行为者的疫苗接种率低，患甲型肝炎的风险高。

IF 2.5 4区医学

Enfermedades infecciosas y microbiologia clinica Pub Date : 2024-05-01 DOI: 10.1016/j.eimc.2023.03.003

Marta Fernandez-Fuertes , Juan Macias , Anaïs Corma-Gomez , Adolfo Salazar-Gonzalez , Alejandro Gonzalez-Serna , Pilar Rincon , Maria J. Arriaza-Estevez , Ana Fuentes-Lopez , Luis M. Real , Juan A. Pineda

{"title":"Low rate of vaccination and risk of incident hepatitis A among HIV-infected men who have sex with men in Seville, Southern Spain","authors":"Marta Fernandez-Fuertes , Juan Macias , Anaïs Corma-Gomez , Adolfo Salazar-Gonzalez , Alejandro Gonzalez-Serna , Pilar Rincon , Maria J. Arriaza-Estevez , Ana Fuentes-Lopez , Luis M. Real , Juan A. Pineda","doi":"10.1016/j.eimc.2023.03.003","DOIUrl":"10.1016/j.eimc.2023.03.003","url":null,"abstract":"<div><h3>Background</h3><p>Periodic outbreaks of hepatitis A (HAV) infection in men who have sex with men (MSM) have been reported. Low vaccination uptake in HIV-infected individuals could drive new outbreaks. We aimed at evaluating the incidence of and risk factors for HAV infection in people living with HIV (PLWH) in our area. We also assessed the rates of HAV vaccination.</p></div><div><h3>Methods</h3><p>This was a prospective cohort study. 915 patients were included, 272 (30%) of them were anti-HAV seronegative at baseline.</p></div><div><h3>Results</h3><p>Twenty-six (9.6%) susceptible individuals became infected. Incident cases peaked in 2009–2010 and 2017–2018. Incident HAV infection was independently associated with MSM [adjusted odds ratio (95% confidence ratio): 4.39 (1.35–14.27), <em>p</em>  <!-->0.014]. One hundred and five (38.6%) HAV seronegative patients were vaccinated, 21 (20%) of them did not respond, and one (1%) patient lost immunity against HAV. Four (29%) non-responders to vaccination showed incident HAV 5–9 years afterwards.</p></div><div><h3>Conclusions</h3><p>The incidence of HAV infection in a cohort of well-controlled PLWH remains low and stable, with intermittent outbreaks involving mainly non-immunized MSM. A significant proportion of PLWH remain susceptible to HAV infection due to insufficient vaccine uptake and limited response to vaccination. Importantly, patients not responding to HAV vaccination continue at risk of infection.</p></div>","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":"42 5","pages":"Pages 251-256"},"PeriodicalIF":2.5,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43814215","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Reactivation of cutaneous tuberculosis induced by trauma: A case report 创伤诱发的皮肤结核再活化：病例报告

IF 2.5 4区医学

Enfermedades infecciosas y microbiologia clinica Pub Date : 2024-05-01 DOI: 10.1016/j.eimc.2024.02.007

Ali Mert , Abdurrahman Kaya , Sibel Yıldız Kaya

引用次数: 0

Lesiones papulares eritematosas en un paciente procedente de Venezuela 委内瑞拉一名患者的红斑丘疹性病变

IF 2.5 4区医学

Enfermedades infecciosas y microbiologia clinica Pub Date : 2024-05-01 DOI: 10.1016/j.eimc.2023.10.012

Amparo Broseta Tamarit , Víctor Dios Guillán , Marta Jiménez Mayordomo , Victoria Domínguez-Márquez

引用次数: 0

Síndrome destructivo centrofacial: una etiología inusual 中枢性面部毁损综合征：一种不寻常的病因

IF 2.5 4区医学

Enfermedades infecciosas y microbiologia clinica Pub Date : 2024-05-01 DOI: 10.1016/j.eimc.2023.12.005

Camilo Ruiz Mejía, Andrés Felipe Lozano Camayo, Juan David Ruiz Restrepo, Gloria Andrea Vargas Suaza

引用次数: 0