Enfermedades infecciosas y microbiologia clinica最新文献

Bacteriemia por Elizabethkingia anophelis en paciente con neumonía 一名肺炎患者的伊丽莎白金格氏 anophelis 菌血症

IF 2.6 4区医学

Enfermedades infecciosas y microbiologia clinica Pub Date : 2024-08-01 DOI: 10.1016/j.eimc.2024.03.015

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Tubercular longitudinally extensive transverse myelitis: An unmissable zebra grazing the Indian medical field 结核性纵向广泛横贯性脊髓炎：印度医学界一匹不可忽视的斑马

IF 2.6 4区医学

Enfermedades infecciosas y microbiologia clinica Pub Date : 2024-08-01 DOI: 10.1016/j.eimc.2024.04.002

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Respuesta a la carta sobre las limitaciones del diagnóstico de meningitis tuberculosa 回复关于结核性脑膜炎诊断局限性的信件

IF 2.6 4区医学

Enfermedades infecciosas y microbiologia clinica Pub Date : 2024-08-01 DOI: 10.1016/j.eimc.2024.04.007

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Caracterización de la reinfección de prótesis articular tras recambio en 2 tiempos (infección de la prótesis del 2.o tiempo). Un estudio multicéntrico 二期假体置换（二期假体感染）后关节置换术后再感染的特征。多中心研究

IF 2.6 4区医学

Enfermedades infecciosas y microbiologia clinica Pub Date : 2024-08-01 DOI: 10.1016/j.eimc.2023.05.003

{"title":"Caracterización de la reinfección de prótesis articular tras recambio en 2 tiempos (infección de la prótesis del 2.o tiempo). Un estudio multicéntrico","authors":"","doi":"10.1016/j.eimc.2023.05.003","DOIUrl":"10.1016/j.eimc.2023.05.003","url":null,"abstract":"<div><h3>Introduction</h3><p>Two-stage exchange is the gold standard in the surgical management of prosthetic joint infection (PJI). However, perioperative reinfections (RePJI) can occur to newly inserted prosthesis, which highlights the importance of an adequate antibiotic prophylaxis, although there is scarce evidence in this field. Our objective was to evaluate the characteristics of RePJI, its prognosis and the antibiotic prophylaxis that is commonly used in second-stage surgery.</p></div><div><h3>Methods</h3><p>Multicentric retrospective observational study in Spanish hospitals including patients with RePJI between 2009 and 2018.</p></div><div><h3>Results</h3><p>We included 92 patients with RePJI from 12 hospitals. The most frequent isolated microorganism was <em>Staphylococcus epidermidis</em> in 35 cases (38.5%); 61.1% of staphylococci were methiciliin-resistant. In 12 cases (13%), the same microorganism causing the primary PJI was isolated in RePJI. When comparing with the microbiology of primary PJI, there were more cases caused by Gram-negative bacteria (the most frequent was <em>Pseudomonas</em> spp.) and less by Gram-positive bacteria. Failure occurred in 69 cases (75%). There were 43 different courses of antibiotic prophylaxis after the second-stage surgery; the most frequent was a unique preoperative cefazolin dose, but most patients received prophylaxis before and after the second-stage surgery (61 cases).</p></div><div><h3>Conclusions</h3><p>The most frequent microorganisms in RePJI are coagulase-negative staphylococci, although Gram-negative bacteria, especially <em>Pseudomonas</em> spp. are also common. There is a significant heterogeneity in antibiotic prophylaxis for a second-stage surgery. ReIPJI treatment has a high failure rate.</p></div>","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":null,"pages":null},"PeriodicalIF":2.6,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123490424","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Enhancing pneumococcal bacteraemia diagnosis: A comparative assessment of culture-independent assays (MALDI–TOF–MS Sepsityper® module and a lateral flow inmunochromatography test) 加强肺炎球菌菌血症诊断：独立于培养的检测方法（MALDI-TOF-MS Sepsityper® 模块和侧流免疫层析检测）的比较评估

IF 2.6 4区医学

Enfermedades infecciosas y microbiologia clinica Pub Date : 2024-08-01 DOI: 10.1016/j.eimc.2024.02.001

{"title":"Enhancing pneumococcal bacteraemia diagnosis: A comparative assessment of culture-independent assays (MALDI–TOF–MS Sepsityper® module and a lateral flow inmunochromatography test)","authors":"","doi":"10.1016/j.eimc.2024.02.001","DOIUrl":"10.1016/j.eimc.2024.02.001","url":null,"abstract":"<div><h3>Introduction</h3><p>Pneumococcal bacteraemia is a major contributor to global morbidity and mortality. Traditional culture-based methods lack sensitivity and are time-consuming. This study aimed to assess the effectiveness of two culture-independent assays, the MALDI–TOF–MS Sepsityper® module and the lateral flow inmunochromatography test (LFICT) with the Standard F® <em>Streptococcus pneumoniae</em>, directly from positive blood culture (BC) bottles.</p></div><div><h3>Methods</h3><p>A prospective study was conducted from December 2021 to July 2022. For all BC positives for <span><span>S. pneumoniae</span></span> a double centrifugation protocol was implemented. The resulting pellet was subsequently processed using both techniques.</p></div><div><h3>Results</h3><p>The LFICT showed exceptional performance with 100% sensitivity and specificity, outperforming the MALDI–TOF–MS Sepsityper® module, which achieved 85.2% sensitivity and 100% specificity. Nevertheless, the combination of these assays offers a robust and comprehensive approach to diagnosis.</p></div><div><h3>Conclusions</h3><p>The simultaneous use of both techniques offers a promising alternative that can be integrated into routine practices directly from BC samples.</p></div>","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":null,"pages":null},"PeriodicalIF":2.6,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140126947","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Ecografía clínica: presente y futuro en enfermedades infecciosas 临床超声：传染病的现状与未来

IF 2.6 4区医学

Enfermedades infecciosas y microbiologia clinica Pub Date : 2024-08-01 DOI: 10.1016/j.eimc.2024.01.007

引用次数: 0

Comparación de medios de cultivo para la detección de Legionella spp. en muestras de agua sanitaria: adaptación a la norma ISO 11731:2017 用于检测卫生水样中军团菌属的培养基比较：ISO 11731:2017 适应版

IF 2.6 4区医学

Enfermedades infecciosas y microbiologia clinica Pub Date : 2024-08-01 DOI: 10.1016/j.eimc.2024.03.013

{"title":"Comparación de medios de cultivo para la detección de Legionella spp. en muestras de agua sanitaria: adaptación a la norma ISO 11731:2017","authors":"","doi":"10.1016/j.eimc.2024.03.013","DOIUrl":"10.1016/j.eimc.2024.03.013","url":null,"abstract":"<div><h3>Introduction</h3><p>Water sample culturing is the reference method to detect <em>Legionella</em> spp. in sanitary facilities. Until 2017, UNE-EN ISO 11731 only included the GVPC medium, which inhibits interfering microbiota but hinders the growth of <em>Legionella</em> spp. To improve its recovery, the new standard incorporates the BCYE medium into the working protocol.</p></div><div><h3>Methods</h3><p>We inoculated 1,306 sanitary water samples onto BCYE and GVPC according to an accredited internal procedure. We compared the number of cfu/L of <em>Legionella</em> spp. detected in both media.</p></div><div><h3>Results</h3><p>The median in BCYE was 2,000cfu/L higher than in GVPC (p=0.000). In the presence of high amounts of interfering microbiota, both media were similar; in the absence or low interfering microbiota BCYE was four times more sensitive than GVPC (p=0.000).</p></div><div><h3>Conclusion</h3><p>Including BCYE in the analysis of sanitary water significantly improves the recovery of <em>Legionella</em> spp. in low contaminated samples.</p></div>","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":null,"pages":null},"PeriodicalIF":2.6,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140768978","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Intertrigo inguinal: ¿infeccioso o inflamatorio? 腹股沟间肌：是损伤性还是炎症性？

IF 2.6 4区医学

Enfermedades infecciosas y microbiologia clinica Pub Date : 2024-08-01 DOI: 10.1016/j.eimc.2023.12.007

引用次数: 0

Drug burden index in people living with HIV over 50 years of age in a real clinical practice cohort 真实临床实践队列中 50 岁以上艾滋病毒感染者的药物负担指数

IF 2.6 4区医学

Enfermedades infecciosas y microbiologia clinica Pub Date : 2024-08-01 DOI: 10.1016/j.eimc.2023.04.010

{"title":"Drug burden index in people living with HIV over 50 years of age in a real clinical practice cohort","authors":"","doi":"10.1016/j.eimc.2023.04.010","DOIUrl":"10.1016/j.eimc.2023.04.010","url":null,"abstract":"<div><h3>Objectives</h3><p>To determine DBI and its relationship with polypharmacy<span> and pharmacotherapeutic complexity (PC) in a cohort of PLWH over 50 years of age at follow-up of pharmacotherapy in a tertiary hospital.</span></p></div><div><h3>Methods</h3><p>Observational and retrospective study that included PLWH in active antiretroviral treatment over 50 years of age who have been followed up in outpatient pharmacy services. Pharmacotherapeutic complexity was estimated through Medication Regimen Complexity Index (MRCI). Collected variables included comorbidities, current prescriptions and its classification according to anticholinergic and sedative activity and associated risk of falls.</p></div><div><h3>Results</h3><p>Studied population included 251 patients (85.7% men; median age: 58 years, interquartile range: 54–61). There was a high prevalence of high DBI scores (49.2%). High DBI was significantly correlated with a high PC, polypharmacy, psychiatric comorbidity and substances abuse (<em>p</em>  =85), antidepressant drugs (N06A) (<em>n</em>  <span>41) and antiepileptic drugs (N03A) (</span><em>n</em>  =18). Most frequent drugs associated with risk of falls were anxiolytics (N05B) (<em>n</em>  =61) and antidepressants (N06A) (<em>n</em>  <!-->41).</p></div><div><h3>Conclusion</h3><p>The DBI score in older PLWH is high and it is related to PC, polypharmacy, mental diseases and substance abuse as is the prevalence of fall-related drugs. Control of these parameters as well as the reduction of the sedative and anticholinergic load should be included in the lines of work in the pharmaceutical care of people living with HIV+.</p></div>","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":null,"pages":null},"PeriodicalIF":2.6,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134903980","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Resumen ejecutivo de las Guías Española de Diagnóstico y Manejo de Enfermedades Febriles Importadas de la Sociedad Española de Medicina Tropical y Salud Internacional (SEMTSI), el Grupo de Patología Importada de la Sociedad Española de Enfermedades Infecciosas y microbiología clínica (GEPI-SEIMC), la Sociedad Española de Medicina de Familia y Comunitaria (SEMFYC), la Sociedad Española de Médicos de Atención Primaria (SEMERGEN) y la Sociedad Española de Medicina de Urgencias y Emergencias (SEMES) 西班牙热带医学和国际健康学会 (SEMTSI)、西班牙传染病和临床微生物学学会进口病理学小组 (GEPI-SEIMC)、西班牙家庭和社区医学学会 (SEMFYC)、西班牙初级保健医生学会 (SEMERGEN) 和西班牙急诊医学学会 (SEMES) 制定的《西班牙进口发热疾病诊断和管理指南》执行摘要。

IF 2.6 4区医学

Enfermedades infecciosas y microbiologia clinica Pub Date : 2024-08-01 DOI: 10.1016/j.eimc.2024.05.002

{"title":"Resumen ejecutivo de las Guías Española de Diagnóstico y Manejo de Enfermedades Febriles Importadas de la Sociedad Española de Medicina Tropical y Salud Internacional (SEMTSI), el Grupo de Patología Importada de la Sociedad Española de Enfermedades Infecciosas y microbiología clínica (GEPI-SEIMC), la Sociedad Española de Medicina de Familia y Comunitaria (SEMFYC), la Sociedad Española de Médicos de Atención Primaria (SEMERGEN) y la Sociedad Española de Medicina de Urgencias y Emergencias (SEMES)","authors":"","doi":"10.1016/j.eimc.2024.05.002","DOIUrl":"10.1016/j.eimc.2024.05.002","url":null,"abstract":"<div><p>The Spanish Society of Tropical Medicine and International Health (SEMTSI), the Spanish Society of Infectious Diseases and Clinical Microbiology (SEIMC), the Spanish Society of Emergency Medicine (SEMES), the Spanish Society of Primary Care Physicians (SEMERGEN) and the Spanish Society of Family and Community Medicine (SEMFYC) have elaborated a consensus statement on the diagnosis and management of patients with imported febrile illnesses.</p><p>Twenty authors with different backgrounds and representing different healthcare perspectives (ambulatory primary care, travel and tropical medicine specialists, emergency medicine, hospital care, microbiology and parasitology and public health), identified 39 relevant questions, which were organized in 7 thematic blocks. After a systematic review of the literature and a thoughtful discussion, the authors elaborated 125 recommendations, as well as several tables and figures to be used as a consulting tool. The present executive summary shows a selection of some of the most relevant questions and recommendations included in the guidelines.</p></div>","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":null,"pages":null},"PeriodicalIF":2.6,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0213005X24002489/pdfft?md5=fbe6e606c7bc1604d760adfc33bfd98f&pid=1-s2.0-S0213005X24002489-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141547251","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0