Enfermedades infecciosas y microbiologia clinica最新文献_第10页

Comments to the article “First reported case of imported scrub typhus in Spain: A disease to consider in travellers” 对文章 "西班牙首例报告的输入性恙虫病病例：旅行者应注意的一种疾病"

IF 2.5 4区医学

Enfermedades infecciosas y microbiologia clinica Pub Date : 2024-01-01 DOI: 10.1016/j.eimc.2023.09.002

Moisés León-Ruiz , Ritwik Ghosh , Julián Benito-León

引用次数: 0

Listeriosis no gestacional: cambios en frecuencia, formas clínicas y factores pronósticos 非妊娠李斯特菌病：发病率、临床形式和预后因素的变化

IF 2.5 4区医学

Enfermedades infecciosas y microbiologia clinica Pub Date : 2024-01-01 DOI: 10.1016/j.eimc.2022.10.001

Luis Corral , Ignacio de los Santos , Carmen Quereda , Fernando Acebrón , Patricia Ruiz-Garbajosa , Alfonso Muriel , Íñigo Corral

{"title":"Listeriosis no gestacional: cambios en frecuencia, formas clínicas y factores pronósticos","authors":"Luis Corral , Ignacio de los Santos , Carmen Quereda , Fernando Acebrón , Patricia Ruiz-Garbajosa , Alfonso Muriel , Íñigo Corral","doi":"10.1016/j.eimc.2022.10.001","DOIUrl":"10.1016/j.eimc.2022.10.001","url":null,"abstract":"<div><h3>Introduction</h3><p><em>Listeria monocytogenes</em> infection is a severe disease affecting mainly aged people and patients with immune depression. The incidence of listeriosis seems to be increasing. In the present study cases of listeriosis from two hospitals are analyzed with the aims of studying changes in its incidence, clinical forms of presentation and possible factors associated with mortality.</p></div><div><h3>Methods</h3><p>Retrospective multicentric study of patients with culture-proven listeriosis in two university hospitals in Madrid between 1977 and 2021. Epidemiological and clinical variables, as well as factors for immune depression, complementary studies and treatments were registered. Factors associated with mortality were analyzed.</p></div><div><h3>Results</h3><p>A total of 194 cases of listeriosis were analyzed. The incidence of listeriosis among in-patients increased through the study period, with a significant drop in the number of cases in 2020. The most common clinical presentations were isolated bacteriemia (37.1%) and central nervous system involvement (CNS) (36.6%). Symptoms of gastroenteritis occurred in 21% of cases. Other focal infections were present in 16.5% of patients, the most frequent were spontaneous bacterial peritonitis (8.2%), cholecystitis (2.1%), respiratory infection (1.5%) and vascular prothesis infection (1.5%). In-hospital mortality was 24.7%. Independent factors associated with mortality at admission were age (odds ratio [OR] 1.027, 95% confidence interval [95% CI]1.003–1.056) and a diagnosis of a solid tumor (OR 3.525, 95% CI1.652–7.524).</p></div><div><h3>Conclusions</h3><p>This study confirms an increasing incidence of listeriosis in our millieu. The most common clinical presentations were isolated bacteriemia and central nervous system involvement. In-hospital mortality was associated with age and the diagnosis of a solid tumor.</p></div>","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":null,"pages":null},"PeriodicalIF":2.5,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127312179","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Relevancia de los enterovirus en la meningitis neonatal 肠道病毒与新生儿脑膜炎的相关性

IF 2.5 4区医学

Enfermedades infecciosas y microbiologia clinica Pub Date : 2024-01-01 DOI: 10.1016/j.eimc.2022.07.010

Elisenda Moliner-Calderón , Núria Rabella-Garcia , Eulalia Turón-Viñas , Gemma Ginovart-Galiana , Josep Figueras-Aloy

{"title":"Relevancia de los enterovirus en la meningitis neonatal","authors":"Elisenda Moliner-Calderón , Núria Rabella-Garcia , Eulalia Turón-Viñas , Gemma Ginovart-Galiana , Josep Figueras-Aloy","doi":"10.1016/j.eimc.2022.07.010","DOIUrl":"10.1016/j.eimc.2022.07.010","url":null,"abstract":"<div><h3>Introduction</h3><p>Enterovirus (EV) infections are the most frequent infections in the neonatal period and in many cases lead to hospital admission of the newborn (NB).</p><p>The aim of this study was to determine the incidence of EV in the etiology of neonatal meningitis and to define the clinical characteristics of newborns with EV meningitis.</p></div><div><h3>Material and method</h3><p>Retrospective observational cohort study. Including 91 NBs with meningitis and gestational age greater than 34 weeks gestational age (GA) attended in our center over a period of 16 years.</p></div><div><h3>Results</h3><p>The percentage of NBs with EV meningitis was higher than that of NBs with bacterial meningitis (BM) and accounted for 78% (<em>n</em>  <!-->71). Half of the NBs with EV infection had a history of epidemic environment among their caregivers. Fever was present in 96% of cases as a clinical sign and, in general, sensory disturbances represented the main neurological alterations. Antibiotics (ATB) were given to 71.4% of patients with EV infection.</p><p>Detection of EV in CSF samples showed a high sensitivity for the diagnosis of EV meningitis. The most frequently implicated EV types were echovirus 11, coxsackievirus B5, echovirus 18, 25 and 7.</p></div><div><h3>Conclusions</h3><p>The results of this series show that enterovirus infection is a common cause of neonatal meningitis. These data underline the importance of rapid EV testing of infants with suspected meningitis. This allows early diagnosis and reduces antibiotic treatment, hospitalization time and related costs.</p></div>","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":null,"pages":null},"PeriodicalIF":2.5,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124292428","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Dolor abdominal como síntoma guía de la fiebre de origen desconocido 腹痛是不明原因发热的先兆症状

IF 2.5 4区医学

Enfermedades infecciosas y microbiologia clinica Pub Date : 2024-01-01 DOI: 10.1016/j.eimc.2023.08.002

Carmen Agustí-Barjau , Anna Gamell , Mariona F. de Sevilla , Gemma Pons-Tomàs

引用次数: 0

Rapid diagnostic tests for dengue would reduce hospitalizations, healthcare costs and antibiotic prescriptions in Spain: A cost-effectiveness analysis 在西班牙，登革热快速诊断测试将减少住院、医疗费用和抗生素处方:成本效益分析。

IF 2.5 4区医学

Enfermedades infecciosas y microbiologia clinica Pub Date : 2024-01-01 DOI: 10.1016/j.eimc.2022.12.009

Daniel Camprubí-Ferrer , Francesco Ramponi , Leire Balerdi-Sarasola , Ana Godoy , Elisa Sicuri , José Muñoz

{"title":"Rapid diagnostic tests for dengue would reduce hospitalizations, healthcare costs and antibiotic prescriptions in Spain: A cost-effectiveness analysis","authors":"Daniel Camprubí-Ferrer , Francesco Ramponi , Leire Balerdi-Sarasola , Ana Godoy , Elisa Sicuri , José Muñoz","doi":"10.1016/j.eimc.2022.12.009","DOIUrl":"10.1016/j.eimc.2022.12.009","url":null,"abstract":"<div><h3>Background</h3><p>Current gold standard diagnostic techniques for dengue are expensive and time-consuming. Rapid diagnostic tests (RDTs) have been proposed as alternatives, although data about their potential impact in non-endemic areas is scarce.</p></div><div><h3>Methods</h3><p>We performed a cost-effectiveness analysis comparing the costs of dengue RDTs to the current standard of care for the management of febrile returning travelers in Spain. Effectiveness was measured in terms of potential averted hospital admissions and reduction of empirical antibiotics, based on 2015–2020 dengue admissions at Hospital Clinic Barcelona (Spain).</p></div><div><h3>Results</h3><p>Dengue RDTs were associated with 53.6% (95% CI: 33.9–72.5) reduction of hospital admissions and were estimated to save 289.08–389.31€ per traveler tested. Moreover, RDTs would have avoided the use of antibiotics in 46.4% (95% CI: 27.5–66.1) of dengue patients.</p></div><div><h3>Discussion</h3><p>Implementation of dengue RDTs for the management of febrile travelers is a cost-saving strategy that would lead to a reduction of half of dengue admissions and a reduction of inappropriate antibiotics in Spain.</p></div>","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":null,"pages":null},"PeriodicalIF":2.5,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0213005X2300006X/pdfft?md5=ed4bcfae8e45bd8b26b68ae52600abca&pid=1-s2.0-S0213005X2300006X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47716128","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

How should we generalise the diagnosis of dengue as it spreads to more and more regions of the world? 随着登革热在世界越来越多的地区蔓延，我们应该如何推广登革热的诊断？

IF 2.5 4区医学

Enfermedades infecciosas y microbiologia clinica Pub Date : 2024-01-01 DOI: 10.1016/j.eimc.2023.09.003

María José Cárdenas-Isasi , Miguel J. Martínez-Yoldi , Juan Carlos Galán

引用次数: 0

Streptococcus bovis infection of the central nervous system in adults: Report of 4 cases and literature review 成人中枢神经系统牛链球菌感染：4例报告及文献复习。

IF 2.5 4区医学

Enfermedades infecciosas y microbiologia clinica Pub Date : 2024-01-01 DOI: 10.1016/j.eimc.2022.06.010

Juan Corredoira Sánchez , Blanca Ayuso García , Eva María Romay Lema , María José García-Pais , Ana I. Rodríguez-Macias , Patricia Capón González , Rocio Otero López , Ramón Rabuñal Rey , Pilar Alonso García

{"title":"Streptococcus bovis infection of the central nervous system in adults: Report of 4 cases and literature review","authors":"Juan Corredoira Sánchez , Blanca Ayuso García , Eva María Romay Lema , María José García-Pais , Ana I. Rodríguez-Macias , Patricia Capón González , Rocio Otero López , Ramón Rabuñal Rey , Pilar Alonso García","doi":"10.1016/j.eimc.2022.06.010","DOIUrl":"10.1016/j.eimc.2022.06.010","url":null,"abstract":"<div><h3>Objectives</h3><p>To describe the clinical features, history and association with intestinal disease in central nervous system (CNS) <em>S. bovis</em> infections.</p></div><div><h3>Methods</h3><p>Four cases of <em>S. bovis</em> CNS infections from our institution are presented. Additionally a systematic literature review of articles published between 1975 and 2021 in PubMed/MEDLINE was conducted.</p></div><div><h3>Results</h3><p>52 studies with 65 cases were found; five were excluded because of incomplete data. In total 64 cases were analyzed including our four cases: 55 with meningitis and 9 with intracranial focal infections. Both infections were frequently associated with underlying conditions (70.3%) such as immunosuppression (32.8%) or cancer (10.9%). In 23 cases a biotype was identified, with biotype <span>II</span> being the most frequent (69.6%) and <em>S. pasteurianus</em> the most common within this subgroup. Intestinal diseases were found in 60.9% of cases, most commonly neoplasms (41.0%) and <span><em>Strongyloides</em></span> infestation (30.8%). Overall mortality was 17.1%, with a higher rate in focal infection (44.4% <em>vs</em> 12.7%; <em>p</em>  <!-->0.001).</p></div><div><h3>Conclusions</h3><p>CNS infections due to <em>S. bovis</em><span> are infrequent and the most common clinical form is meningitis. Compared with focal infections, meningitis had a more acute course, was less associated with endocarditis and had a lower mortality. Immunosuppression and intestinal disease were frequent in both infections.</span></p></div>","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":null,"pages":null},"PeriodicalIF":2.5,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49142977","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Epidemiological changes in invasive Streptococcus pyogenes infection during the UK alert period: A molecular comparative analysis from a tertiary Spanish hospital in 2023 英国预警期间侵袭性化脓性链球菌感染的流行病学变化：2023 年西班牙一家三级医院的分子对比分析

IF 2.5 4区医学

Enfermedades infecciosas y microbiologia clinica Pub Date : 2024-01-01 DOI: 10.1016/j.eimc.2023.09.004

Alfredo Maldonado-Barrueco , Iván Bloise , Emilio Cendejas-Bueno , Francisco López-Rodrigo , Julio García-Rodríguez , Fernando Lázaro-Perona

{"title":"Epidemiological changes in invasive Streptococcus pyogenes infection during the UK alert period: A molecular comparative analysis from a tertiary Spanish hospital in 2023","authors":"Alfredo Maldonado-Barrueco , Iván Bloise , Emilio Cendejas-Bueno , Francisco López-Rodrigo , Julio García-Rodríguez , Fernando Lázaro-Perona","doi":"10.1016/j.eimc.2023.09.004","DOIUrl":"10.1016/j.eimc.2023.09.004","url":null,"abstract":"<div><h3>Objectives</h3><p>To study the genomic epidemiology of <span><em>Streptococcus pyogenes</em></span> causing bloodstream infections (GAS-BSI) in a Spanish tertiary hospital during the United Kingdom invasive <em>S. pyogenes</em> outbreak alert.</p></div><div><h3>Methods</h3><p>Retrospective epidemiological analysis of GAS-BSI during the January–May 2017–2023 period. WGS was performed using Ion torrent GeneStudio™ S5 system for <em>emm</em> typing and identification of superantigen genes in <em>S. pyogenes</em> isolated during the 2022–2023 UK outbreak alert.</p></div><div><h3>Results</h3><p>During 2023, there were more cases of GAS-BSI compared to the same period of previous year with a non-significant increase in children. Fourteen isolates were sequenced. The <em>emm1</em> (6/14, 42.9%) and <em>emm12</em> (2/14, 14.3%) types predominated; 5 of 6 (75%) <em>emm1</em> isolates were from the M1<sub>UK</sub> clone. The most detected superantigen genes were <em>speG</em> (12/14, 85.7%), <em>speC</em> (10/14, 71.4%), <em>speJ</em> (7/14, 50%), and <em>speA</em> (5/15, 33.3%). <em>speA</em> and <em>speJ</em> were predominant in M1<sub>UK</sub> clone.</p></div><div><h3>Conclusions</h3><p>Our genomic epidemiology in 2023 is similar to the reported data from the UK outbreak alert in the same period and different from previous national <em>S. pyogenes</em> surveillance reports.</p></div>","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":null,"pages":null},"PeriodicalIF":2.5,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135850246","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Absceso muscular de etiología poco frecuente

IF 2.5 4区医学

Enfermedades infecciosas y microbiologia clinica Pub Date : 2024-01-01 DOI: 10.1016/j.eimc.2023.04.005

María Martínez-Bra , Tomás Galeano-Fernández , Eugenio Garduño Eseverri , Francisco-Félix Rodríguez-Vidigal

引用次数: 0

Hallazgo inusual en cultivo de herida esternal 胸骨伤口培养的异常发现

IF 2.5 4区医学

Enfermedades infecciosas y microbiologia clinica Pub Date : 2024-01-01 DOI: 10.1016/j.eimc.2023.06.004

Clara Rodríguez Pinilla , Nerea Cuesta Urbano , Ana Flores Guerrero , Eugenio Garduño Eseverri

引用次数: 0