{"title":"Knowledge, attitudes and practices in HIV-related chronic inflammation and cardiovascular risk in Spain","authors":"","doi":"10.1016/j.eimc.2023.07.005","DOIUrl":"10.1016/j.eimc.2023.07.005","url":null,"abstract":"<div><h3>Background</h3><div>People with HIV (PWH) in suppressive antiretroviral treatment suffer from chronic inflammation-related comorbidities, mainly cardiovascular diseases. However, given the lack of specific evidence about inflammation in PWH, clinical guidelines do not provide recommendations for the management of this issue. To date, physician awareness of inflammation in PWH remains unclear. We analyzed the knowledge, attitudes, and practices (KAP) related to inflammation, particularly in the clinical management of PWH, of infectious disease specialists (IDS)/internists compared to other specialists treating inflammation directly (rheumatologists) or its cardiovascular consequences (cardiologists).</div></div><div><h3>Methods</h3><div>A committee of IDS/internists treating PWH, cardiologists, and rheumatologists designed the KAP questionnaire. The survey was completed by 405 participants (135 physicians per specialty) stratified by Spanish geography, hospital size, and number of PWH under care (IDS/internists only).</div></div><div><h3>Results</h3><div>IDS/internists treating PWH scored higher than cardiologists and rheumatologists on knowledge of inflammation (5.5<!--> <!-->±<!--> <!-->1.4 out of 8 points vs. 5.2<!--> <!-->±<!--> <!-->1.3 and 4.6<!--> <!-->±<!--> <!-->1.4 points, respectively; <em>p</em> <!--><<!--> <!-->0.05). Nevertheless, rheumatologists showed the most proactive attitude toward inflammation (i.e., biomarkers monitoring, anti-inflammatory drug prescription and cardiologist referral), followed by cardiologists and IDS/internists (13<!--> <!-->±<!--> <!-->3 of a total of 16 points vs. 11<!--> <!-->±<!--> <!-->3 and 10<!--> <!-->±<!--> <!-->3.3 points, respectively; <em>p</em> <!--><<!--> <!-->0.05), irrespective of hospital size and years of experience. Most IDS/internists (59%) include inflammation in their therapeutic recommendations. However, in IDS/internists treating PWH, we observed a negative correlation between years of experience and concern about the clinical consequences of inflammation.</div></div><div><h3>Conclusion</h3><div>Our findings show that, compared to other specialists, infectious disease specialists/internists have high knowledge about inflammation in HIV infection, but, in the absence of scientific evidence to base their decisions on inflammatory markers, the therapeutic implications are scarce. The results support the need for more evidence on the monitoring and treatment of inflammation in PWH.</div></div>","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":"42 9","pages":"Pages 484-491"},"PeriodicalIF":2.6,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135761245","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Domingo Fernández Vecilla , Mikel Joseba Urrutikoetxea Gutiérrez , Mary Paz Roche Matheus , Felicitas Elena Calvo Muro , José Luis Díaz de Tuesta del Arco
{"title":"Clinical and microbiological characteristics of Eggerthella lenta causing bacteremia","authors":"Domingo Fernández Vecilla , Mikel Joseba Urrutikoetxea Gutiérrez , Mary Paz Roche Matheus , Felicitas Elena Calvo Muro , José Luis Díaz de Tuesta del Arco","doi":"10.1016/j.eimc.2024.05.003","DOIUrl":"10.1016/j.eimc.2024.05.003","url":null,"abstract":"<div><div><span><em>Eggerthella lenta</em></span><span> is an obligate anaerobic, Gram-positive bacilli, belonging to the human microbiota of gastrointestinal and female reproductive tracts, oral cavity and prostate gland. In this article, we aim to describe clinical and microbiological characteristics of seven </span><em>E. lenta</em> strains causing bacteremia. We conducted a descriptive retrospective study including all <em>E. lenta</em> strains causing bacteremia, from February 2019 to August 2023 at the Basurto University Hospital. Seven patients were included in the study with a mean age of 72.7 years. Six patients presented risk factors associated with bacterial infections. All patients were admitted to the hospital because of suspicious of bloodstream infection associated with abdominal symptoms for intravenous antibiotic treatment. Four <em>E. lenta</em> isolates were resistant to penicillin, while all isolates presented high MICs to piperacillin/tazobactam and low MICs to amoxicillin/clavulanic acid. All patients recovered without no complications.</div></div>","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":"42 9","pages":"Pages 512-515"},"PeriodicalIF":2.6,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142586572","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Fernando de la Calle-Prieto , Marta Arsuaga , Graciela Rodríguez-Sevilla , Nancy Sandoval Paiz , Marta Díaz-Menéndez
{"title":"The current status of arboviruses with major epidemiological significance in Europe","authors":"Fernando de la Calle-Prieto , Marta Arsuaga , Graciela Rodríguez-Sevilla , Nancy Sandoval Paiz , Marta Díaz-Menéndez","doi":"10.1016/j.eimc.2024.09.002","DOIUrl":"10.1016/j.eimc.2024.09.002","url":null,"abstract":"<div><div>Currently, an increasing impact of some arboviruses has been observed in Europe, mainly Dengue (DENV), Chikungunya (CHIKV), Zika (ZIKV), West Nile (WNV), and Crimean-Congo hemorrhagic fever (CCHFV) analyzed through a One Health perspective that considers their expansion across the continent. Arboviruses are primarily transmitted by vectors such as mosquitoes and ticks, with human activities and climate change playing crucial roles in their spread. The review highlights the ecological and epidemiological aspects of arboviruses, emphasizing the roles of diverse hosts and reservoirs, including humans, animals, and vectors, in their life cycles. The influence of climate change on the ecology of the vector, which potentially favors the arbovirus transmission, is also reviewed. Focusing on diagnosis, prevention and in the absence of specific treatments, the importance of understanding vector–host interactions and environmental impacts to develop effective control and prevention strategies is emphasized. Ongoing research on vaccines and therapies is crucial to mitigate the public health impact of these diseases.</div></div>","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":"42 9","pages":"Pages 516-526"},"PeriodicalIF":2.6,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142586573","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Rafael García-Cañas , Francisco Javier Areta-Jiménez
{"title":"Caracterización de las infecciones de herida entre pacientes procedentes de la guerra ruso-ucraniana en un hospital Role 4","authors":"Rafael García-Cañas , Francisco Javier Areta-Jiménez","doi":"10.1016/j.eimc.2024.06.013","DOIUrl":"10.1016/j.eimc.2024.06.013","url":null,"abstract":"","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":"42 9","pages":"Pages 540-542"},"PeriodicalIF":2.6,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142586575","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"¿Fascitis necrosante por una picadura de araña?","authors":"","doi":"10.1016/j.eimc.2024.01.006","DOIUrl":"10.1016/j.eimc.2024.01.006","url":null,"abstract":"","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":"42 9","pages":"Pages 529-530"},"PeriodicalIF":2.6,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140082771","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Marta Pérez-Abeledo , Fernando Martín , Susana Jiménez , Juan Carlos Sanz
{"title":"Caso confirmado de sarampión en vacunada: papel de la determinación de avidez de IgG específica","authors":"Marta Pérez-Abeledo , Fernando Martín , Susana Jiménez , Juan Carlos Sanz","doi":"10.1016/j.eimc.2024.05.005","DOIUrl":"10.1016/j.eimc.2024.05.005","url":null,"abstract":"","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":"42 9","pages":"Pages 539-540"},"PeriodicalIF":2.6,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142586372","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Análisis de los motivos de solicitud de serología del virus de la inmunodeficiencia humana (VIH) en urgencias diferentes a los definidos en la estrategia de detección dirigida del programa «Urgències VIHgila» y su potencial inclusión en un futuro documento de consenso","authors":"","doi":"10.1016/j.eimc.2023.12.012","DOIUrl":"10.1016/j.eimc.2023.12.012","url":null,"abstract":"<div><h3>Objective</h3><div>To describe other reasons for requesting HIV serology in emergency departments (ED) other than the six defined in the SEMES-GESIDA consensus document (DC-SEMES-GESIDA) and to analyze whether it would be efficient to include any of them in the future.</div></div><div><h3>Method</h3><div>Review of all HIV serologies performed during 2 years in 20 Catalan EDs. Serologies requested for reasons not defined by the DC-SEMES-GESIDA were grouped by common conditions, the prevalence (95% <span>C</span>I) of seropositivity for each condition was calculated, and those whose 95% confidence lower limit was > 0.1% were considered efficient. Sensitivity analysis considered that serology would have been performed on 20% of cases attended and the remaining 80% would have been seronegative.</div></div><div><h3>Results</h3><div>There were 8044 serologies performed for 248 conditions not recommended by DC-SEMES-GESIDA, in 17 there were seropositive, and in 12 the performance of HIV serology would be efficient. The highest prevalence of detection corresponded to patients from countries with high HIV prevalence (7.41%, 0.91–24.3), lymphopenia (4.76%, 0.12–23.8), plateletopenia (4.37%, 1.20–10.9), adenopathy (3.45%, 0.42–11.9), meningoencephalitis (3.12%, 0.38–10.8) and drug use (2.50%, 0.68–6.28). Sensitivity analysis confirmed efficiency in 6 of them: country with high HIV prevalence origin, plateletopenia, drug abuse, toxic syndrome, behavioral-confusional disorder-agitation and fever of unknown origin.</div></div><div><h3>Conclusion</h3><div>The DC-SEMES-GESIDA targeted HIV screening strategy in the ED could efficiently include other circumstances not previously considered; the most cost-effective would be origin from a country with high HIV prevalence, plateletopenia, drug abuse, toxic syndrome, behavioral-confusional-agitation disorder and fever of unknown origin.</div></div>","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":"42 9","pages":"Pages 492-500"},"PeriodicalIF":2.6,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139561772","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}