Enfermedades infecciosas y microbiologia clinica最新文献

{"title":"Rapid antibiotic susceptibility testing (RAST) of blood cultures in enterobacteria with inducible chromosomal AmpC-type β-lactamase","authors":"Blanca Carrasco,&nbsp;Gloria Zaragoza,&nbsp;David M. Arana,&nbsp;Yolanda Hernández-Hermida,&nbsp;Juan-Ignacio Alós","doi":"10.1016/j.eimc.2023.12.008","DOIUrl":"10.1016/j.eimc.2023.12.008","url":null,"abstract":"<div><h3>Introduction</h3><p>Early and adequate treatment of bloodstream infections decreases patient morbidity and mortality. The objective is to develop a preliminary method for rapid antibiotic susceptibility testing (RAST) in enterobacteria with inducible chromosomal AmpC.</p></div><div><h3>Methods</h3><p>RAST was performed directly on spiked blood cultures of 49 enterobacteria with inducible chromosomal AmpC. Results were read at 4, 6 and 8<!--> <!-->h of incubation. Commercial broth microdilution was considered the reference method. Disks of 10 antibiotics were evaluated.</p></div><div><h3>Results</h3><p>The proportion of readable tests at 4<!--> <!-->h was 85%. All RAST could be read at 6 and 8<!--> <!-->h.</p><p>For most antibiotics, the S or R result at 4, 6 and 8<!--> <!-->h was greater than 80% after tentative breakpoints were established and Area of Technical Uncertainty was defined.</p></div><div><h3>Conclusions</h3><p>This preliminary method seems to be of practical use, although it should be extended to adjust the breakpoints and differentiate them by species.</p></div>","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":"42 4","pages":"Pages 205-207"},"PeriodicalIF":2.5,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139499295","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diagnóstico tardío de VIH en paciente migrante con infección oportunista importada","authors":"Daniel N. Marco ,&nbsp;Oriana Omaña-Iglesias ,&nbsp;Gabriela Caballero ,&nbsp;Francesc Marco","doi":"10.1016/j.eimc.2023.12.003","DOIUrl":"10.1016/j.eimc.2023.12.003","url":null,"abstract":"","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":"42 4","pages":"Pages 225-226"},"PeriodicalIF":2.5,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139095752","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nasopharyngeal colonization and invasive disease in Streptococcus pneumoniae: Two critical aspects of the pneumococcal pathogenesis with many similarities","authors":"Julio Sempere ,&nbsp;Jose Yuste","doi":"10.1016/j.eimc.2024.01.001","DOIUrl":"10.1016/j.eimc.2024.01.001","url":null,"abstract":"","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":"42 4","pages":"Pages 169-171"},"PeriodicalIF":2.5,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139825547","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Auritidibacter ignavus en muestras óticas de pacientes pediátricos. Presentación de 2 casos y revisión de la literatura","authors":"Pablo González-Moreno ,&nbsp;Martina Araujo-Sánchez ,&nbsp;Jonathan Fernández-Suárez ,&nbsp;Javier Fernández-Dominguez ,&nbsp;Jose Luis Llorente ,&nbsp;María Soledad Zapico-González","doi":"10.1016/j.eimc.2023.10.011","DOIUrl":"10.1016/j.eimc.2023.10.011","url":null,"abstract":"<div><h3>Introduction</h3><p>The development and research of new technologies for identifying microorganisms, has allowed the identification of hitherto unknown bacteria. <em>Auritidibacter ignavus</em> is a newly described Gram-positive rod possibly associated with otitis, although its role as an etiologic agent in otitis is currently controversial.</p></div><div><h3>Methods</h3><p>We report two cases of recurrent otitis in paediatric patients in which <em>A. ignavus</em> was isolated and review the previous cases reported in the literature.</p></div><div><h3>Results</h3><p>All the isolates were identified as <em>A. ignavus</em> by proteomic and genomic methods. Both patients recovered from their symptoms.</p></div><div><h3>Conclusion</h3><p><em>A. ignavus</em> was recovered from ear discharges of paedriatic patients with chronic ear problems. All the cases previously reported in the literature were adults. More evidence is needed for the association between <em>A. ignavus</em> and otitis, since data regarding this species are still scarce.</p></div>","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":"42 4","pages":"Pages 202-204"},"PeriodicalIF":2.5,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138535695","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Epidemiología molecular de la colonización nasofaríngea neumocócica en niños de Sevilla, tras la implementación del programa de vacunación con VNC13 en Andalucía (España)","authors":"Beatriz de Felipe ,&nbsp;Marta Aboza-García ,&nbsp;Verónica González-Galán ,&nbsp;Ignacio Salamanca de la Cueva ,&nbsp;Juan Alfonso Martín-Quintero ,&nbsp;Benito Amil-Pérez ,&nbsp;Cristóbal Coronel-Rodríguez ,&nbsp;María Ángeles Palacios-Soria ,&nbsp;María Isabel García Ruiz-Santaquiteria ,&nbsp;María José Torres-Sánchez ,&nbsp;Francisco Javier Morón ,&nbsp;Juan A. Cordero-Varela ,&nbsp;Pablo Obando-Pacheco ,&nbsp;Ignacio Obando","doi":"10.1016/j.eimc.2022.11.005","DOIUrl":"10.1016/j.eimc.2022.11.005","url":null,"abstract":"<div><h3>Background</h3><p>The 13-valent pneumococcal conjugate vaccine (PCV13) universal vaccination program was introduced in December 2016 in Andalusia.</p></div><div><h3>Methods</h3><p>A cross-sectional study was conducted on the molecular epidemiology of pneumococcal nasopharyngeal colonization. A total of 397 healthy children were recruited from primary healthcare centres in Seville for the periods 1/4/2018 to 28/2/2020 and 1/11/2021 to 28/2/2022 (PCV13 period). Data from a previous carriage study conducted among healthy and sick children from 1/01/2006 to 30/06/2008 (PCV7 period) were used for comparison of serotype/genotype distributions and antibiotic resistance rates.</p></div><div><h3>Results</h3><p>Overall, 76 (19%) children were colonized with <em>S. pneumoniae</em> during the PCV13 period and there were information available from 154 isolates collected during the PCV7 period. Colonization with PCV13 serotypes declined significantly in the PCV13 period compared with historical controls (11 vs. 38%, <em>P</em> <em>=</em> <!-->0.0001), being serotypes 19F (8%), 3 (1%) and 6B (1%) the only circulating vaccine type<strong>s</strong>. Serotypes 15B/C and 11A were the most frequently identified non-PCV13 serotypes during the PCV13 period (14% and 11%, respectively); the later one increased significantly between time periods (<em>P</em> <em>=</em> <!-->0.04). Serotype 11A was exclusively associated in the PCV13 period with ampicillin-resistant variants of the Spain9V-ST156 clone (ST6521 and genetically related ST14698), not detected in the preceding period.</p></div><div><h3>Conclusions</h3><p>There was a residual circulation of vaccine types following PCV13 introduction, apart from serotype 19F. Serotype 11A increased between PCV13 and PCV7 periods due to emergence and clonal expansion of ampicillin-resistant genotype ST6521.</p></div>","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":"42 4","pages":"Pages 172-178"},"PeriodicalIF":2.5,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121889765","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Executive summary: Guidelines for the diagnosis and treatment of septic arthritis in adults and children, developed by the GEIO (SEIMC), SEIP and SECOT","authors":"Natividad Benito ,&nbsp;Juan Carlos Martínez-Pastor ,&nbsp;Jaime Lora-Tamayo ,&nbsp;Javier Ariza ,&nbsp;José Baeza ,&nbsp;Joaquín Belzunegui-Otano ,&nbsp;Javier Cobo ,&nbsp;María-Dolores del-Toro ,&nbsp;Cesar G. Fontecha ,&nbsp;Lluís Font-Vizcarra ,&nbsp;Juan P. Horcajada ,&nbsp;Laura Morata ,&nbsp;Oscar Murillo ,&nbsp;Joan M. Nolla ,&nbsp;Esmeralda Núñez-Cuadros ,&nbsp;Carlos Pigrau ,&nbsp;María Eugenia Portillo ,&nbsp;Dolors Rodríguez-Pardo ,&nbsp;Beatriz Sobrino-Díaz ,&nbsp;Jesús Saavedra-Lozano","doi":"10.1016/j.eimc.2023.07.003","DOIUrl":"10.1016/j.eimc.2023.07.003","url":null,"abstract":"<div><p>Infection of a native joint, commonly referred to as septic arthritis, is a medical emergency because of the risk of joint destruction and subsequent sequelae. Its diagnosis requires a high level of suspicion. These guidelines for the diagnosis and treatment of septic arthritis in children and adults are intended for use by any physician caring for patients with suspected or confirmed septic arthritis. They have been developed by a multidisciplinary panel with representatives from the Bone and Joint Infections Study Group (GEIO) belonging to the Spanish Society of Infectious Diseases and Clinical Microbiology (SEIMC), the Spanish Society of Paediatric Infections (SEIP) and the Spanish Society of Orthopaedic Surgery and Traumatology (SECOT), and two rheumatologists. The recommendations are based on evidence derived from a systematic literature review and, failing that, on the opinion of the experts who prepared these guidelines. A detailed description of the background, methods, summary of evidence, the rationale supporting each recommendation, and gaps in knowledge can be found online in the complete document.</p></div>","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":"42 4","pages":"Pages 208-214"},"PeriodicalIF":2.5,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0213005X2300188X/pdfft?md5=95023c5c115e63fb19eb5073fbf07c14&pid=1-s2.0-S0213005X2300188X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135588823","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Artritis de muñeca por Mycobacterium malmoense","authors":"Raquel Fernández González ,&nbsp;Ricardo Fernández Rodríguez ,&nbsp;Pedro Luis Prieto Casal ,&nbsp;Eva Salgado","doi":"10.1016/j.eimc.2023.11.001","DOIUrl":"10.1016/j.eimc.2023.11.001","url":null,"abstract":"","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":"42 4","pages":"Pages 221-223"},"PeriodicalIF":2.5,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138572425","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cerebral and spinal neurocysticercosis with extensive myocysticercosis presenting with new-onset convulsive status epilepticus and myopathic symptoms","authors":"Ritwik Ghosh ,&nbsp;Moisés León-Ruiz ,&nbsp;Souvik Dubey ,&nbsp;Julián Benito-León","doi":"10.1016/j.eimc.2023.11.003","DOIUrl":"10.1016/j.eimc.2023.11.003","url":null,"abstract":"","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":"42 4","pages":"Pages 223-225"},"PeriodicalIF":2.5,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138631863","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Un caso inusual de dolor ocular y ceguera unilateral","authors":"Yiraldine Herrera-Martínez,&nbsp;Álvaro De Bonilla-Damiá,&nbsp;Irene Acevedo-Bañez,&nbsp;José M. Jiménez-Hoyuela García","doi":"10.1016/j.eimc.2023.10.001","DOIUrl":"10.1016/j.eimc.2023.10.001","url":null,"abstract":"","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":"42 4","pages":"Pages 215-217"},"PeriodicalIF":2.5,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138683185","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Progresión temporal de la distribución de los serotipos de Streptococcus pneumoniae productores de enfermedad neumocócica invasiva en Galicia (España) y su relación con la resistencia a antibióticos (periodo 2011-2021)","authors":"Isabel Losada-Castillo ,&nbsp;Isolina Santiago-Pérez ,&nbsp;Pedro Miguel Juiz-Gonzalez ,&nbsp;Susana Méndez-Lage ,&nbsp;María Jesús Purriños-Hermida ,&nbsp;Alberto Malvar ,&nbsp;José Andrés Agulla-Budiño ,&nbsp;Grupo de estudio de neumococo de Galicia","doi":"10.1016/j.eimc.2022.12.007","DOIUrl":"10.1016/j.eimc.2022.12.007","url":null,"abstract":"<div><h3>Introduction</h3><p><em>Streptococcus pneumoniae</em> causes serious diseases in the susceptible population. The 13-valent pneumococci conjugate vaccine (PCV13) was included in the children's calendar in 2011. The objective of the study was to analyze the evolution of pneumococcal serotypes and their resistance after PCV13.</p></div><div><h3>Methods</h3><p>This study included the pneumococci serotyped in Galicia in 2011-2021. Antibiotic susceptibility was analyzed following EUCAST criteria. The data was analyzed in 3 sub-periods: initial (2011-2013), middle (2014-2017) and final (2018-2021). The prevalence of serotypes and their percentage of resistance to the most representative antibiotics were calculated.</p></div><div><h3>Results</h3><p>A total of 2.869 isolates were included. Initially, 42.7% isolates presented capsular types included in PCV13, compared to 15.4% at the end. Those included in PCV20 and not in PCV13 and PCV15 were 12.5% at baseline and 41.3% at the end; 26.4% of the isolates throughout the study had serotypes not included in any vaccine. The prevalence of serotype 8 multiplied almost by 8 and that of 12F tripled. The 19A serotype was initially the most resistant, while the resistance of serotypes 11A and 15A increased throughout the study.</p></div><div><h3>Conclusions</h3><p>The introduction of PCV13 in the pediatric population determined a change in pneumococcal serotypes towards those included in PCV20 and those not included in any vaccine. Serotype 19A was initially the most resistant and the 15A, not included in any vaccine, deserves special follow-up. Serotype 8, which increased the most, did not show remarkable resistance.</p></div>","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":"42 4","pages":"Pages 179-186"},"PeriodicalIF":2.5,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114821917","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}