Enfermedades infecciosas y microbiologia clinica最新文献

{"title":"Estreñimiento pertinaz. A propósito de un caso","authors":"J.G. Sánchez Cano , D. Gayoso Cantero , L. Moreno Núñez","doi":"10.1016/j.eimc.2024.02.002","DOIUrl":"10.1016/j.eimc.2024.02.002","url":null,"abstract":"","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":"42 10","pages":"Pages 597-598"},"PeriodicalIF":2.6,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140126941","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Incidencia de infecciones de transmisión sexual y modelos de cribado entre usuarios de profilaxis preexposición frente al VIH","authors":"Oskar Ayerdi ,&nbsp;Eva Orviz ,&nbsp;Adrián Valls Carbó ,&nbsp;Nuria Fernández Piñeiro ,&nbsp;Mar Vera García ,&nbsp;Teresa Puerta López ,&nbsp;Juan Ballesteros Martín ,&nbsp;Carmen Rodríguez Martín ,&nbsp;Begoña Baza Caraciolo ,&nbsp;Clara Lejarraga Cañas ,&nbsp;Jorge-Alfredo Pérez-García ,&nbsp;Dulce Carrió ,&nbsp;Mónica García Lotero ,&nbsp;María Ferreras Forcada ,&nbsp;Montserrat González Polo ,&nbsp;Montserrat Raposo Utrilla ,&nbsp;Alberto Delgado-Iribarren ,&nbsp;Jorge Del Romero-Guerrero ,&nbsp;Vicente Estrada Pérez","doi":"10.1016/j.eimc.2024.01.003","DOIUrl":"10.1016/j.eimc.2024.01.003","url":null,"abstract":"<div><h3>Introduction</h3><div>There is discussion about the frequency of STI screening among pre-exposure prophylaxis (PrEP) users. The aim of this study was to analyze the incidence of STIs and to evaluate different screening models in order to optimize the follow-up.</div></div><div><h3>Methodology</h3><div>A prospective study was conducted between 2017 and 2023, including 138 PrEP users in a STI clinic. Participants were tested for STIs every three months. Unscheduled visits were performed for those with STI-related symptoms or for people who were notified for an STI by a sexual partner. We performed a survival analysis of repeated events, estimating the cumulative incidence (<span>C</span>I) and incidence rate (IR).</div></div><div><h3>Results</h3><div>The overall CI by quarterly screening was 8.3 (95% CI: 7.6–9.1) infections per person over six years, with a decreasing trend. The most frequently diagnosed pathogen was <em>Neisseria gonorrhoeae</em>, with a IR of 0.76 (95% CI: 0.68–0.84). If the frequency of screening is reduced to every six months, the IR of STIs is reduced by (95% CI: 0.5–0.66) infections per user per year, and at 12 months by 0.82 (95% CI: 0.73–0.89). In the case of no pharyngeal or urethral screening, IR is reduced by 0.37 (95% CI: 0.32–0.42) infections per person per year and in those over 35 years of age by 0.33 (95% CI: 0.25–0.4). Eliminating unscheduled visits, the reduction in IR is 0.33 (95% CI: 0.24–0.42).</div></div><div><h3>Conclusions</h3><div>The incidence of STIs among PrEP users is high, especially in the rectum, but it does not increase over time. STI screening could be optimized reducing the frequency of pharyngeal and urethral testing, particularly in those over 35 years of age. It is essential to redistribute health resources for unscheduled visits, which have been shown to be the most cost-effective screening.</div></div>","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":"42 10","pages":"Pages 570-576"},"PeriodicalIF":2.6,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139871472","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"First characterization of a Klebsiella pneumoniae clinical isolate producing VEB-1 and OXA-436 in Spain","authors":"Laura Pastor Gómez ,&nbsp;Ana Isabel Aller García ,&nbsp;Inmaculada López-Hernández ,&nbsp;Lorena López-Cerero","doi":"10.1016/j.eimc.2024.07.001","DOIUrl":"10.1016/j.eimc.2024.07.001","url":null,"abstract":"","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":"42 10","pages":"Pages 602-604"},"PeriodicalIF":2.6,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143148768","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"COVID-19 and disruptions in HIV care: Assessment and future directions","authors":"Javier De La Torre Lima,&nbsp;Nicolas Jiménez García","doi":"10.1016/j.eimc.2024.05.006","DOIUrl":"10.1016/j.eimc.2024.05.006","url":null,"abstract":"","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":"42 10","pages":"Pages 543-545"},"PeriodicalIF":2.6,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143148479","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Tolerance of Atovacuona/proguanil in off-label indication in children","authors":"Lorea Vicente Elcano ,&nbsp;Cecilia Muruzábal Pino ,&nbsp;Cristina Calvo ,&nbsp;Milagros García López Hortelano","doi":"10.1016/j.eimc.2024.06.012","DOIUrl":"10.1016/j.eimc.2024.06.012","url":null,"abstract":"","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":"42 10","pages":"Pages 605-606"},"PeriodicalIF":2.6,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143148767","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Inflammation in HIV: A persistent challenge","authors":"Julia Barrado ,&nbsp;Vicente Estrada","doi":"10.1016/j.eimc.2024.09.007","DOIUrl":"10.1016/j.eimc.2024.09.007","url":null,"abstract":"","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":"42 9","pages":"Page 467"},"PeriodicalIF":2.6,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142586380","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Respuesta a «Caracterización de las infecciones de herida entre pacientes procedentes de la guerra ruso-ucraniana en un hospital Role 4»","authors":"María del Mar Rodero Roldán ,&nbsp;Valentín Yuste Benavente ,&nbsp;Ana Isabel López Calleja ,&nbsp;Juan Manuel García-Lechuz","doi":"10.1016/j.eimc.2024.06.014","DOIUrl":"10.1016/j.eimc.2024.06.014","url":null,"abstract":"","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":"42 9","pages":"Page 542"},"PeriodicalIF":2.6,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142586576","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Recurrent invasive pneumococcal disease (RIPD) in an immunocompromised patient","authors":"Ivonne Andrea Torres Jiménez ,&nbsp;Sara de Miguel García ,&nbsp;Julio Sempere García ,&nbsp;Juan Carlos Sanz Moreno","doi":"10.1016/j.eimc.2024.06.004","DOIUrl":"10.1016/j.eimc.2024.06.004","url":null,"abstract":"","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":"42 9","pages":"Pages 533-535"},"PeriodicalIF":2.6,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141710475","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Meningitis tuberculosa por Mycobacterium africanum en España, a propósito de un caso","authors":"Nuria Torrellas Bertran ,&nbsp;Gemma Garcia Continente ,&nbsp;Oscar Villarreal","doi":"10.1016/j.eimc.2024.06.007","DOIUrl":"10.1016/j.eimc.2024.06.007","url":null,"abstract":"","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":"42 9","pages":"Pages 536-538"},"PeriodicalIF":2.6,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141850259","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Utilidad predictiva de mortalidad de las escalas qSOFA, NEWS y GYM en el paciente anciano con infección en urgencias: estudio EDEN-5","authors":"","doi":"10.1016/j.eimc.2023.07.004","DOIUrl":"10.1016/j.eimc.2023.07.004","url":null,"abstract":"<div><h3>Objective</h3><div>To analyze the prognostic accuracy of the scores NEWS, qSOFA, GYM used in hospital emergency department (ED) in the assessment of elderly patients who consult for an infectious disease.</div></div><div><h3>Methods</h3><div>Data from the EDEN (Emergency Department and Elderly Needs) cohort were used. This retrospective cohort included all patients aged ≥<!--> <!-->65<!--> <!-->years seen in 52 Spanish EDs during two weeks (from 1/4/2019 to 7/4/2019 and 30/3/2020 to 5/4/2020) with an infectious disease diagnosis in the emergency department. Demographic variables, comorbidities, Charlson and Barthel index and needed scores parameters were recorded. The predictive capacity for 30-day mortality of each scale was estimated by calculating the area under the receiver operating characteristic (ROC) curve, and sensitivity and specificity were calculated for different cut-off points. The primary outcome variable was 30-day mortality.</div></div><div><h3>Results</h3><div>Six thousand fifty-four patients were analyzed. Median age was 80<!--> <!-->years (IQR 73-87) and 45.3% women. Nine hundred and ninety-three (16.4%) patients died. NEWS score had better AUC than qSOFA (0.765; 95%<!--> <!-->CI: 0.725-0.806, vs. 0.700; 95%<!--> <span>C</span>I: 0.653-0.746; <em>P</em> <!-->&lt;<!--> <!-->.001) and GYM (0.716; 95%<!--> <!-->CI: 0.675-0.758; <em>P</em> <!-->=<!--> <!-->.024), and there was no difference between qSOFA and GYM (<em>P</em> <!-->=<!--> <!-->.345). The highest sensitivity scores for 30-day mortality were GYM ≥<!--> <!-->1 point (85.4%) while the qSOFA score ≥<!--> <!-->2 points showed high specificity. In the case of the NEWS scale, the cut-off point ≥<!--> <!-->4 showed high sensitivity, while the cut-off point NEWS ≥<!--> <!-->8 showed high specificity.</div></div><div><h3>Conclusion</h3><div>NEWS score showed the highest predictive capacity for 30-day mortality. GYM score ≥<!--> <!-->1 showed a great sensitivity, while qSOFA ≥<!--> <!-->2 scores provide the highest specificity but lower sensitivity.</div></div>","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":"42 9","pages":"Pages 468-477"},"PeriodicalIF":2.6,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135852634","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}