Paula García-Sánchez , Belén Parra Rodríguez , Rosario López López , Miguel Ángel Molina Gutiérrez , Marta Bueno Barriocanal , María de Ceano-Vivas la Calle
{"title":"Retrospective study of acute mastoiditis in children in Spain attended in a Pediatric Emergency department","authors":"Paula García-Sánchez , Belén Parra Rodríguez , Rosario López López , Miguel Ángel Molina Gutiérrez , Marta Bueno Barriocanal , María de Ceano-Vivas la Calle","doi":"10.1016/j.eimc.2024.02.011","DOIUrl":"10.1016/j.eimc.2024.02.011","url":null,"abstract":"<div><h3>Objective</h3><p>To analyze the cases of acute mastoiditis, characteristics, management and complications in children attended in the emergency department.</p></div><div><h3>Methods</h3><p>Retrospective study of acute mastoiditis in a Spanish tertiary hospital over a 6-year period (2018–2023).</p></div><div><h3>Results</h3><p>One hundred two episodes of acute mastoiditis were analyzed (54% males, median age 1.8 years). Microorganisms were isolated in one third of cases, mainly <em>Streptococcus pyogenes</em> (64% of ear secretion cultures). Complications occurred in 27.5%, primarily subperiosteal abscess. A younger age, absence of vaccination schedule, previous history of otitis, cochlear implant carriers or white blood cell counts and C-reactive protein levels were not associated with complications. Complicated cases had longer hospitalizations. Treatment included antibiotics, corticosteroids, and surgery in 50% of cases.</p></div><div><h3>Conclusions</h3><p>This study shows an increase of acute mastoiditis during 2023, with a relevant role of <em>S. pyogenes</em>. A younger age, absence of vaccination, personal history of otitis or cochlear implant, blood cell counts and C-reactive protein levels were not associated with complications.</p></div>","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":"42 5","pages":"Pages 263-266"},"PeriodicalIF":2.5,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140766307","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Amaia Torrecilla Ugarte , Irene Díaz de Santiago , Rebeca Bermejo Garcés , Roberto Muñoz Arrondo
{"title":"Ictus, más allá del riesgo cardiovascular","authors":"Amaia Torrecilla Ugarte , Irene Díaz de Santiago , Rebeca Bermejo Garcés , Roberto Muñoz Arrondo","doi":"10.1016/j.eimc.2023.10.007","DOIUrl":"10.1016/j.eimc.2023.10.007","url":null,"abstract":"","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":"42 5","pages":"Pages 272-273"},"PeriodicalIF":2.5,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138535700","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Consuelo García-Sánchez, Julio García-Rodríguez, Guillermo Ruiz-Carrascoso
{"title":"Clinical and microbiological findings of recurrent Campylobacter spp. gastroenteritis in a tertiary care hospital","authors":"Consuelo García-Sánchez, Julio García-Rodríguez, Guillermo Ruiz-Carrascoso","doi":"10.1016/j.eimc.2022.09.007","DOIUrl":"https://doi.org/10.1016/j.eimc.2022.09.007","url":null,"abstract":"<div><h3>Introduction</h3><p><span><span>Campylobacter</span></span><span> spp. is the leading cause of bacterial enteritis in industrialized countries, but the literature about its recurrence is scarce. The objective of this study is to analyze a case series of recurrent campylobacteriosis in adult and pediatric patients.</span></p></div><div><h3>Methods</h3><p>During a two-year period, the demographic, clinical and microbiological data were collected retrospectively from patients who met the clinical criteria of recurrent <em>Campylobacter</em><span> spp. gastroenteritis. Enteropathogens were identified by a multiplex-PCR gastrointestinal pathogens panel. When </span><em>Campylobacter</em> spp. was detected, the stool sample was cultured in specific medium and tested for antibiotic susceptibility.</p></div><div><h3>Results</h3><p>Twenty-four (2.03%) out of 1180 patients with <em>Campylobacter</em> spp. positive-PCR met the inclusion criteria. Thirteen patients suffered from underlying diseases, and 11 had no known risk factors but they were all pediatric patients. From the 24 patients were documented 70 episodes. One patient had two episodes of bacteremia. Coinfection/co-detection with other enteropathogens was found in 10 patients being <span><em>Giardia intestinalis</em></span> the most frequent. Twelve (22.6%) out of 53 isolates were resistant to macrolides. One patient had two isolates of multi-drug resistant <em>C. coli</em>, only susceptible to gentamicin.</p></div><div><h3>Conclusion</h3><p>The results suggest the presence of underlying diseases in most adult patients with recurrent <em>Campylobacter</em> spp. infections, particularly primary immunodeficiency. Most of the pediatric patients with recurrent campylobacteriosis lack of known risk factors. Concomitant detection with other enteropathogens was common. The resistance to macrolides was much higher as compared with previous reported rates.</p></div>","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":"42 5","pages":"Pages 257-262"},"PeriodicalIF":2.5,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140825128","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Fátima Castillo , Eulàlia Turón-Viñas , Laura Armendariz , Emma Carbonell , Nuria Rabella , Margarita del Cuerpo , Elisenda Moliner
{"title":"Characteristics of enterovirus infection associated neurologic disease in a pediatric population in Spain","authors":"Fátima Castillo , Eulàlia Turón-Viñas , Laura Armendariz , Emma Carbonell , Nuria Rabella , Margarita del Cuerpo , Elisenda Moliner","doi":"10.1016/j.eimc.2023.02.002","DOIUrl":"10.1016/j.eimc.2023.02.002","url":null,"abstract":"<div><h3>Introduction</h3><p>Enteroviruses are a type of RNA-strained virus with more than 100 different genotypes. Infection can be asymptomatic, and, if any, symptoms can range from mild to severe. Some patients can develop neurological involvement, such as aseptic meningitis, encephalitis, or even cardiorespiratory failure. However, in children, the risk factors for developing severe neurological involvement are not well understood. The aim of this retrospective study was to analyze some characteristics associated with severe neurological involvement in children hospitalized for neurological disease after enterovirus infection.</p></div><div><h3>Methods</h3><p>retrospective observational study analyzing clinical, microbiological and radiological data of 174 children hospitalized from 2009 to 2019 in our hospital. Patients were classified according to the World Health Organization case definition for neurological complications in hand, foot and mouth disease.</p></div><div><h3>Results</h3><p>Our findings showed that, in children between 6 months old and 2 years of age, the appearance of neurological symptoms within the first 12<!--> <span>h from infection onset—especially if associated with skin rash—was a significant risk factor for severe neurological involvement. Detection of enterovirus in cerebrospinal fluid was more likely in patients with aseptic meningitis. By contrast, other biological samples (e.g., feces or nasopharyngeal fluids) were necessary to detect enterovirus in patients with encephalitis. The genotype most commonly associated with the most severe neurological conditions was EV-A71. E-30 was mostly associated with aseptic meningitis.</span></p></div><div><h3>Conclusions</h3><p>Awareness of the risk factors associated with worse neurological outcomes could help clinicians to better manage these patients to avoid unnecessary admissions and/or ancillary tests.</p></div>","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":"42 5","pages":"Pages 242-250"},"PeriodicalIF":2.5,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42346198","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Juan González del Castillo , Maria Jesus Perez Elias , Iría Miguens , Begoña Espinosa , Ricardo Juárez , Lourdes Piedrafita Lozoya , Patricia Trenc , Jesus Alvarez Manzanares , María José Marchena , Raquel Rodríguez , Nayra Cabrera , Pilar Grajal , Carmen Navarro , Pascual Piñera , Federico García , Santiago Moreno , Oscar Miro
{"title":"Decálogo para promover la implementación y mejora de las recomendaciones para el diagnóstico temprano del VIH en los servicios de urgencias","authors":"Juan González del Castillo , Maria Jesus Perez Elias , Iría Miguens , Begoña Espinosa , Ricardo Juárez , Lourdes Piedrafita Lozoya , Patricia Trenc , Jesus Alvarez Manzanares , María José Marchena , Raquel Rodríguez , Nayra Cabrera , Pilar Grajal , Carmen Navarro , Pascual Piñera , Federico García , Santiago Moreno , Oscar Miro","doi":"10.1016/j.eimc.2023.03.004","DOIUrl":"10.1016/j.eimc.2023.03.004","url":null,"abstract":"<div><p>Early diagnosis of HIV is still a challenge. Emergency Departments (EDs) suppose ideal settings for the early detection of HIV, since patients with high prevalence of hidden HIV infection are frequently attending those services. In 2020, the Spanish Society of Emergency and Emergency Medicine (SEMES) published a series of recommendations for the early diagnosis of patients with suspected HIV infection and their referral and follow-up in the EDs as part of its «Deja tu huella» program. However, the application of these recommendations has been very heterogeneous in our country. Considering this, the working group of the HIV hospital network led by the SEMES has motivated the drafting of a decalogue, with the aim of promoting the implementation and improvement of protocols for the early diagnosis of HIV in Spanish EDs.</p></div>","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":"42 5","pages":"Pages 267-271"},"PeriodicalIF":2.5,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125272573","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Maite Nogales-Garcia , Naiara Parraza Diez , Andoni Vargas Axpe , Rafael Velasco Garcia , Ane Larrabeiti-Etxebarria , Ignacio Roy Lopez-Cano , Inmaculada Atrio Alvarez , Asier Lopez de Arcaute Trincado , Eva María Fernandez Lopez de Vicuña , Ester Saez de Adana Arroniz , Carlos Martínez Martínez , Joseba Portu Zapirain
{"title":"Eliminación del virus de la hepatitis C en un centro penitenciario: una experiencia de 18 años","authors":"Maite Nogales-Garcia , Naiara Parraza Diez , Andoni Vargas Axpe , Rafael Velasco Garcia , Ane Larrabeiti-Etxebarria , Ignacio Roy Lopez-Cano , Inmaculada Atrio Alvarez , Asier Lopez de Arcaute Trincado , Eva María Fernandez Lopez de Vicuña , Ester Saez de Adana Arroniz , Carlos Martínez Martínez , Joseba Portu Zapirain","doi":"10.1016/j.eimc.2023.01.002","DOIUrl":"10.1016/j.eimc.2023.01.002","url":null,"abstract":"<div><h3>Introduction</h3><p>Despite the decrease of hepatitis C in Spanish prisons in the last years, it still remains a reservoir for infection. The aim of this work is to analyze the characteristics of these patients and the response to antiviral treatment over the last 18 years.</p></div><div><h3>Methods</h3><p>Retrospective observational study in inmates of Araba penitentiary center diagnosed with HCV infection between 2002 and 2020.</p><p>A descriptive analysis of patient characteristics and the response to the 3 antiviral treatment modalities was performed: peg-interferon and ribavirin, peg-interferon, ribavirin and a first-generation protease inhibitor and different combinations of direct-acting antivirals.</p></div><div><h3>Results</h3><p>A total of 248 antiviral treatments were prescribed. Treatment response rate up to 2015 was 65% and 93,7% after that year. Interferon non-responders were the main cause of non-response to treatment in periods 1 and 2 (40-50%). Conversely, in period 3 <em>viral breakthroug</em>h (67%) was the main culprit.</p></div><div><h3>Conclusion</h3><p>After 18 years, active hepatitis C infection in prison inmates has resolved with treatment according to clinical criteria. Therefore, the stay in prison may represent an opportunity to reduce the reservoir of the disease in the community, together with continued health care for those released from prison.</p></div>","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":"42 5","pages":"Pages 236-241"},"PeriodicalIF":2.5,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129144444","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}