Enfermedades infecciosas y microbiologia clinica最新文献_第2页

Infección por Saksenaea vasiformis en España: caso clínico y revisión de la literatura 西班牙的Vasiformis Saksenaea感染：临床病例和文献综述

IF 2.6 4区医学

Enfermedades infecciosas y microbiologia clinica Pub Date : 2025-06-01 DOI: 10.1016/j.eimc.2024.10.011

Iker Villanueva , Laura Guío , Lara Mourelle , Patricia Martín-Playa , Eduardo Vicario , Laura Zaldumbide , Leyre López-Soria , Josune Goikoetxea

{"title":"Infección por Saksenaea vasiformis en España: caso clínico y revisión de la literatura","authors":"Iker Villanueva , Laura Guío , Lara Mourelle , Patricia Martín-Playa , Eduardo Vicario , Laura Zaldumbide , Leyre López-Soria , Josune Goikoetxea","doi":"10.1016/j.eimc.2024.10.011","DOIUrl":"10.1016/j.eimc.2024.10.011","url":null,"abstract":"<div><h3>Introduction</h3><div><em>Saksenaea vasiformis</em> <em>(S. vasiformis)</em> is a filamentous fungus from the Mucorales order, responsible for isolated infections with high morbidity and mortality, especially in tropical or subtropical areas. The objective is to describe the clinical characteristics of the cases reported in Spain.</div></div><div><h3>Methods</h3><div>In addition to presenting a case of <em>S. vasiformis</em> infection treated at Hospital Universitario Cruces in 2023, a systematic literature review was conducted on 17/04/2024, analyzing a total of 11 cases. Epidemiological and clinical data were obtained, and a descriptive analysis was performed.</div></div><div><h3>Results</h3><div>The average age was 64.9 years, with most being male (72.7%) and immunocompetent. Acquisition was related to severe trauma (45.5%) or insect bites (36.4%). 90.1% suffered from skin and soft tissue infections. The diagnostic process was complex, with the following being useful: direct staining (36.4%), culture in specific media (27.3%), molecular techniques (54.5%), and histopathological findings (90.9%). MICs of antifungals was determined in 3 cases, with low MICs for liposomal amphotericin B (L-AMB) and posaconazole, and variable MICs for voriconazole. L-AMB was the most commonly used antifungal, combined in all cases with extensive surgical debridement. Mortality was 45.5%.</div></div><div><h3>Conclusion</h3><div>Infection by <em>S. vasiformis</em> is rare in our environment but clinically significant due to its severity and difficult diagnosis. Rapid recognition, along with early and aggressive debridement and appropriate antifungal treatment, are essential.</div></div>","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":"43 6","pages":"Pages 337-344"},"PeriodicalIF":2.6,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144190078","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Detección y análisis de un brote de Achromobacter xylosoxidans en una unidad de urodinamia 在尿动力学单位发现和分析嗜氧血红杆菌暴发

IF 2.6 4区医学

Enfermedades infecciosas y microbiologia clinica Pub Date : 2025-06-01 DOI: 10.1016/j.eimc.2024.10.010

Simón Juárez Zapata , Carla Benjumea Moreno , Charo Porrón , Carles Alonso-Tarrés

{"title":"Detección y análisis de un brote de Achromobacter xylosoxidans en una unidad de urodinamia","authors":"Simón Juárez Zapata , Carla Benjumea Moreno , Charo Porrón , Carles Alonso-Tarrés","doi":"10.1016/j.eimc.2024.10.010","DOIUrl":"10.1016/j.eimc.2024.10.010","url":null,"abstract":"<div><h3>Introduction</h3><div><em>Achromobacter xylosoxidans</em> is a gramnegative bacillus resistant to multiple antibiotics, present both in the environment and in hospitals. This study describes an outbreak of colonizations and infections by <em>A. xylosoxidans</em> in the urodynamics unit of the Puigvert Foundation.</div></div><div><h3>Methods</h3><div>On November 11, 2022, a patient developed a fever, and <em>A. xylosoxidans</em> was detected in their urine and blood. The case was linked to a recent urodynamic study. As a result, all <em>A. xylosoxidans</em> cases since 2018 were reviewed, and inspections were conducted in the unit, along with the collection of 24 environmental samples.</div></div><div><h3>Results</h3><div>The review identified 21 patients with <em>A. xylosoxidans</em> infections after urodynamic procedures since April 2022. Environmental microbiological controls revealed that pressure transducers were the likely source of infection. Corrective measures included the temporary closure of the unit, thorough cleaning with hypochlorite, use of single-use urinary catheters, daily replacement of equipment lines and pressure transducers, as well as other improvements in disinfection, handling, and workflows. A multidisciplinary team was formed to implement and supervise these actions.</div></div><div><h3>Conclusion</h3><div>The measures resulted in the elimination of the outbreak and the safe resumption of activities in the unit. This incident highlights the importance of continuous surveillance and rapid response in clinical settings to prevent infections and improve patient safety.</div></div>","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":"43 6","pages":"Pages 331-336"},"PeriodicalIF":2.6,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144190159","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Dermatitis causada por diminutos invasores 由微小入侵者引起的皮炎

IF 2.6 4区医学

Enfermedades infecciosas y microbiologia clinica Pub Date : 2025-06-01 DOI: 10.1016/j.eimc.2024.11.010

Karol Nicole Sabas Ortega , José Asensio Gómez , Isabel Zárate Tejero , Javier Sánchez Bernal

引用次数: 0

Fiebre y lesiones cutáneas en paciente en quimioterapia 化疗患者的发烧和皮肤损伤

IF 2.6 4区医学

Enfermedades infecciosas y microbiologia clinica Pub Date : 2025-05-01 DOI: 10.1016/j.eimc.2024.09.009

José González Fernández , Alejandro Tomás Esteban Escudero , Mar García García

引用次数: 0

Absceso en extremidad superior por una especie inusual de Clostridium en una niña inmunocompetente 具有免疫能力的女童因不寻常的梭状芽胞杆菌而导致上肢脓肿

IF 2.6 4区医学

Enfermedades infecciosas y microbiologia clinica Pub Date : 2025-05-01 DOI: 10.1016/j.eimc.2024.12.017

Iker Alonso-González, Nerea Antona-Urieta, Begoña Vilar Achabal, Clara Lejarraga-Cañas

引用次数: 0

A lesion on the right arm for 30 years 右臂上的损伤持续了30年

IF 2.6 4区医学

Enfermedades infecciosas y microbiologia clinica Pub Date : 2025-05-01 DOI: 10.1016/j.eimc.2024.09.013

Ali Mert , Abdurrahman Kaya

引用次数: 0

La mosca fantasma ataca sin ser vista 幽灵苍蝇攻击看不见的

IF 2.6 4区医学

Enfermedades infecciosas y microbiologia clinica Pub Date : 2025-05-01 DOI: 10.1016/j.eimc.2024.11.006

Yolanda García Gambín , María Asunción Iborra-Bendicho , Laura Moreno Parrado , Manuel Segovia-Hernández

引用次数: 0

Precisión diagnóstica de LIAISON MeMed BV® para la bacteriemia en el servicio de urgencias LIAISON MeMed BV®在急诊科细菌性血症诊断的准确性

IF 2.6 4区医学

Enfermedades infecciosas y microbiologia clinica Pub Date : 2025-05-01 DOI: 10.1016/j.eimc.2025.01.001

Laura Serrano Martín , Elena de Rafael González , Javier Cabañas Morafraile , Agustín Julián-Jiménez , en nombre del grupo URGEN-LABQMIC del CHUT del Instituto de Investigación Sanitaria de Castilla La Mancha (IDISCAM)

引用次数: 0

Molecular assays for the initial diagnosis of tuberculosis in a low-prevalence setting: A comparative study 分子检测在低患病率环境下对肺结核的初步诊断：一项比较研究

IF 2.6 4区医学

Enfermedades infecciosas y microbiologia clinica Pub Date : 2025-05-01 DOI: 10.1016/j.eimc.2024.11.013

Ana Fernández-Blázquez , Álvaro Leal-Negredo , Christian Sabater-Cabrera , Miguel Arias-Guillén , José-María García-García , Juan José Palacios Gutiérrez

{"title":"Molecular assays for the initial diagnosis of tuberculosis in a low-prevalence setting: A comparative study","authors":"Ana Fernández-Blázquez , Álvaro Leal-Negredo , Christian Sabater-Cabrera , Miguel Arias-Guillén , José-María García-García , Juan José Palacios Gutiérrez","doi":"10.1016/j.eimc.2024.11.013","DOIUrl":"10.1016/j.eimc.2024.11.013","url":null,"abstract":"<div><h3>Introduction</h3><div>The WHO's End TB Strategy promotes using rapid molecular assays as initial diagnosis to reduce tuberculosis globally. This prospective study assessed commercial molecular platforms’ effectiveness in diagnosing or ruling out tuberculosis (TB) in a low-prevalence setting.</div></div><div><h3>Methods</h3><div>One hundred clinical samples (80 respiratory/20 non-respiratory) were included among all samples routinely received in a mycobacterial laboratory. Five real-time polymerase-chain-reaction (RT-PCR) assays (Xpert-MTB/Rif-Ultra, BDMAX-MDR-TB, RealTime-MTB, FluoroType-MTBDR, Anyplex-MTB/NTM) were characterized and compared through blinded-parallel analysis. Sensitivity, specificity, likelihood ratios, and Cohen's Kappa were calculated to assess the accuracy and agreement of RT-PCR results with culture.</div></div><div><h3>Results</h3><div>Sensitivity ranged 88.89–100%, improving initial screening by 30–40%. Specificity was 96.70–98.98%. RT-PCR showed excellent discriminatory power, as TB patients were 26.9–91.0 times more likely to test positive. Cohen's Kappa showed substantial to excellent concordance (0.78–0.94).</div></div><div><h3>Conclusion</h3><div>RT-PCR improves TB initial diagnosis, offering tailored solutions for diverse laboratories, revolutionizing control strategies with its operational flexibility.</div></div>","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":"43 5","pages":"Pages 272-276"},"PeriodicalIF":2.6,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143894639","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Human Mycobacterium bovis infection: A multicentre retrospective study conducted by the Madrid Study Group for Mycobacteria (GEMIMAD) 人牛分枝杆菌感染：马德里分枝杆菌研究组（GEMIMAD）开展的一项多中心回顾性研究

IF 2.6 4区医学

Enfermedades infecciosas y microbiologia clinica Pub Date : 2025-05-01 DOI: 10.1016/j.eimc.2024.09.014

Loreto Sangorrin-Lapieza , Alba Ruedas-López , Jaime Esteban , Carlos Toro , Laura Barrado , María Jesús Ruiz-Serrano , Jorge Anel , Diego Domingo , Alhena Reyes , Paula López-Roa

{"title":"Human Mycobacterium bovis infection: A multicentre retrospective study conducted by the Madrid Study Group for Mycobacteria (GEMIMAD)","authors":"Loreto Sangorrin-Lapieza , Alba Ruedas-López , Jaime Esteban , Carlos Toro , Laura Barrado , María Jesús Ruiz-Serrano , Jorge Anel , Diego Domingo , Alhena Reyes , Paula López-Roa","doi":"10.1016/j.eimc.2024.09.014","DOIUrl":"10.1016/j.eimc.2024.09.014","url":null,"abstract":"<div><h3>Introduction</h3><div>This study aimed to evaluate trends and clinical characteristics of <em>Mycobacterium bovis</em> human tuberculosis cases, describe the epidemiological features, and compare risk factors associated with extrapulmonary and pulmonary tuberculosis.</div></div><div><h3>Methods</h3><div>A retrospective cohort analysis was conducted on <em>M. bovis</em> infection cases confirmed by culture from seven clinical microbiology laboratories in Madrid, Spain, from 2010 to 2022. Sociodemographic and clinical data were extracted from the hospital database. Tuberculosis (TB) cases were classified as extrapulmonary (EPTB) and pulmonary tuberculosis (PTB), with disseminated TB cases excluded from statistical analysis.</div></div><div><h3>Results</h3><div>Among 3670 patients with <em>Mycobacterium tuberculosis complex</em> infection, <em>M. bovis</em> was identified in 66 patients, representing 1.8% of the total. PTB and EPTB were identified in 45.5% and 39.4% of cases, respectively, with 15.1% having disseminated TB. PTB was significantly associated with males and Spanish nationality, while EPTB was more prevalent among females and those with a rural lifestyle.</div></div><div><h3>Conclusions</h3><div>The study revealed an escalating trend in <em>M. bovis</em> tuberculosis cases. Middle-aged patients, including a substantial immigrant population, were predominantly affected. Female gender and a rural lifestyle were associated to extrapulmonary disease.</div></div>","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":"43 5","pages":"Pages 267-271"},"PeriodicalIF":2.6,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143894631","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0