Enfermedades infecciosas y microbiologia clinica最新文献

{"title":"Uso de isavuconazol en la meningitis criptocócica de un paciente cirrótico","authors":"Jesús Fernández Plaza , Sandra Gregorio Malagón , Manuel Poyato Borrego , Rafael Luque Márquez","doi":"10.1016/j.eimc.2024.04.008","DOIUrl":"10.1016/j.eimc.2024.04.008","url":null,"abstract":"","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":"42 8","pages":"Pages 460-462"},"PeriodicalIF":2.6,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142420220","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lo agresivo no siempre es tumoral: osteomielitis por Bartonella henselae","authors":"","doi":"10.1016/j.eimc.2024.03.010","DOIUrl":"10.1016/j.eimc.2024.03.010","url":null,"abstract":"","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":"42 8","pages":"Pages 457-458"},"PeriodicalIF":2.6,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140796916","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Usefulness of decentralized sequencing networks on antimicrobial resistance surveillance","authors":"","doi":"10.1016/j.eimc.2024.04.011","DOIUrl":"10.1016/j.eimc.2024.04.011","url":null,"abstract":"","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":"42 8","pages":"Pages 462-463"},"PeriodicalIF":2.6,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141275409","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Proponiendo el cambio de denominación de la viruela del mono (Mpox) en español a viruela M","authors":"Francisco Javier Membrillo de Novales , Jaime García Iglesias , Miriam J. Álvarez-Martínez , Luis E. Cuellar , María Eugenia Gutiérrez-Pimentel , Alexis M. Holguin , Virgilio Lezcano , Susana Lloveras , Mariella Raijmakers , Iván Arturo Rodríguez Sabogal , Adriana Sucari , Alfonso J. Rodriguez-Morales , en nombre de la Alianza Latinoamericana de Enfermedades Infecciosas y Microbiología Clínica (ALEIMC)","doi":"10.1016/j.eimc.2024.08.002","DOIUrl":"10.1016/j.eimc.2024.08.002","url":null,"abstract":"","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":"42 8","pages":"Pages 397-398"},"PeriodicalIF":2.6,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142420795","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Desafíos y estrategias en la prevención del dengue: un reto para la salud pública","authors":"","doi":"10.1016/j.eimc.2024.03.007","DOIUrl":"10.1016/j.eimc.2024.03.007","url":null,"abstract":"","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":"42 8","pages":"Pages 464-465"},"PeriodicalIF":2.6,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140767563","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Recently acquired hepatitis C: Epidemiological characteristics and treatment response in a large cohort of MSM living with HIV in Madrid","authors":"","doi":"10.1016/j.eimc.2023.06.011","DOIUrl":"10.1016/j.eimc.2023.06.011","url":null,"abstract":"<div><h3>Introduction</h3><div>We analyzed epidemiological, clinical characteristics, and the response to treatment in people living with HIV (PLHIV) who recently acquired hepatitis C (RAHC) in a multicentre study in Madrid (Spain).</div></div><div><h3>Methods</h3><div>Multicenter, ambispective, observational study of RAHC in men who have sex with men (MSM) infected with HIV. Clinical, epidemiological, and RAHC evolution were recorded prospectively in 2019 and 2020 and retrospectively in 2017 and 2018. In patients who received HCV treatment, sustained virological response (SVR) was provided 12 weeks after the end of treatment in an intention to treat analysis (ITT): all treated patients were included; and in analysis per-protocol (PP): missing patients were excluded.</div></div><div><h3>Results</h3><div>Overall, 133 patients were included. Median (IQR) age was 40 (34.3–46.1) years, 90.9% had at least one previous sexual transmission disease (STD), and 33.6% had previously hepatitis C. More than half of the prospective sample included patients using <em>chemsex</em> related drugs (57.3%), 45.7% of them intravenously. The most prevalent genotype was G1a (66.2%), followed by G4 (11.3%). Ten of 90 patients evaluated for spontaneous cure (11%) cured the infection spontaneously, and 119 had treatment after a median time of 1.8 (0.7–4.6) months: sustained virological response (SVR) was achieved in 90.7% in the ITT and 94.7% in the PP analysis, with no differences regarding the direct-acting antiviral agents (DAA) combination used.</div></div><div><h3>Conclusions</h3><div>MSM infected by HIV with a RAHC were exposed to high-risk sexual behavior. Spontaneous cure rate was low, while SVR after treatment was achieved by more than 90%.</div></div>","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":"42 8","pages":"Pages 414-419"},"PeriodicalIF":2.6,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127486095","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Anticipating the side effects of benznidazole: HLA-B*35 and patch test","authors":"","doi":"10.1016/j.eimc.2024.04.006","DOIUrl":"10.1016/j.eimc.2024.04.006","url":null,"abstract":"<div><h3>Introduction</h3><div>Treatment of Chagas disease frequently causes distress to patients due to a high incidence of adverse effects. Different preemptive tests have been researched to prevent these effects and to allow focus to be given to certain predisposed patients. Benznidazole is the most prescribed Chagas disease treatment in Spain.</div><div>In this work, we analyzed the genetic markers HLA-B*35 allele group and HLA-B*35:05 allele specifically, as well as an allergy patch test, as benznidazole's most frequent adverse effects are cutaneous.</div></div><div><h3>Methods</h3><div>HLA-B intermediate-resolution genotyping was performed followed by a high-resolution level analysis. Cutaneous allergies were tested using strips impregnated with a mixture of benznidazole and placed on the upper back of patients before starting treatment.</div></div><div><h3>Results</h3><div>In our sample of more than 400 patients, there was almost no relationship between any kind of side effect and either of the HLA-B alleles studied. The patch testing was quickly discarded as a preemptive test due to its low sensitivity (16.7%).</div></div><div><h3>Conclusion</h3><div>In conclusion, we were unable to replicate and corroborate genetic markers identified by other groups and there is currently no test that can anticipate the adverse effects of benznidazole, therefore, more investigation should be carried out in this field.</div></div>","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":"42 8","pages":"Pages 430-434"},"PeriodicalIF":2.6,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141023662","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bolas fúngicas en senos paranasales causadas por Syncephalastrum spp.: 2 casos clínicos y revisión de la literatura","authors":"Virginia Cerpa Almenara ,&nbsp;Teresa Nebreda Mayoral ,&nbsp;María Álvarez Álvarez ,&nbsp;Clara Rodrigo Pérez ,&nbsp;Natalia Saiz Sigüenza ,&nbsp;Maria de la Paz Sánchez Hernández","doi":"10.1016/j.eimc.2024.05.001","DOIUrl":"10.1016/j.eimc.2024.05.001","url":null,"abstract":"<div><h3>Introduction</h3><div><em>Syncephalastrum</em> spp. is a mucoral that rarely produces pathology. Fungal balls caused by this genus are infrequent. It requires early diagnosis and treatment to avoid associated morbidity and mortality.</div></div><div><h3>Methods</h3><div>We describe 2<!--> <!-->clinical cases of sinus fungus balls caused by <em>Syncephalastrum</em> spp<em>.</em> and review the literature.</div></div><div><h3>Results</h3><div>Two patients were treated for sinus fungus balls. When their samples were analysed, the aetiology was determined to be <em>Syncephalastrum</em> spp. A case of pulmonary fungus ball due to <em>Syncephalastrum</em> spp. is described in the literature. All cases, including these described in the present study, had a good evolution after treatment.</div></div><div><h3>Conclusions</h3><div><em>Syncephalastrum</em> spp. is a filamentous fungus that should be considered as an aetiology of sinus fungus ball.</div></div>","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":"42 8","pages":"Pages 439-441"},"PeriodicalIF":2.6,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142420794","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sequencing the evolution of vaccinia skin lesions in a laboratory worker: Insights from image analysis","authors":"","doi":"10.1016/j.eimc.2024.04.003","DOIUrl":"10.1016/j.eimc.2024.04.003","url":null,"abstract":"","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":"42 8","pages":"Pages 459-460"},"PeriodicalIF":2.6,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141280779","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Aspectos epidemiológicos y de manejo clínico relativos a las neumonías diagnosticadas en urgencias en pacientes mayores en España: resultados del estudio EDEN-29","authors":"","doi":"10.1016/j.eimc.2023.10.015","DOIUrl":"10.1016/j.eimc.2023.10.015","url":null,"abstract":"<div><h3>Objectives</h3><div>To estimate the incidence of pneumonia diagnosis in elderly patients in Spanish emergency departments (ED), need for hospitalization, adverse events and predictive capacity of biomarkers commonly used in the ED.</div></div><div><h3>Methods</h3><div>Patients ≥<!--> <!-->65 years with pneumonia seen in 52 Spanish EDs were included. We recorded in-hospital and 30-day mortality as adverse events, as well as intensive care unit (ICU) admission among hospitalized patients. Association of 10 predefined variables with adverse events was calculated and expressed as odds ratio (OR) with 95% confidence interval (CI), as well as predictive capacity of 5 commonly used biomarkers in the ED (leukocytes, hemoglobin, C-reactive protein, glucose, creatinine) was investigated using area under the receiver operating characteristic curve (AUC-ROC).</div></div><div><h3>Results</h3><div>591 patients with pneumonia attended in the ED were included (annual incidence of 18.4 per 1,000 inhabitants). A total of 78% were hospitalized. Overall, 30-day mortality was 14.2% and in-hospital mortality was 12.9%. Functional dependency was associated with both events (OR<!--> <!-->=<!--> <!-->4.453, 95%CI<!--> <!-->=<!--> <!-->2.361-8.400; and OR<!--> <!-->=<!--> <!-->3.497, 95%CI<!--> <!-->=<!--> <!-->1.578- 7.750, respectively) as well as severe comorbidity (2.344, 1.363-4.030, and 2.463, 1.252-4.846, respectively). Admission to the ICU during hospitalization occurred in 3.5%, with no associated factors. The predictive capacity of biomarkers was only moderate for creatinine for ICU admission (AUC-ROC<!--> <!-->=<!--> <!-->0.702, 95%CI<!--> <!-->=<!--> <!-->0.536-0.869) and for leukocytes for post-discharge adverse event (0.669, 0.540-0.798).</div></div><div><h3>Conclusions</h3><div>Pneumonia is a frequent diagnosis in elderly patients consulting in the ED. Their functional dependence and comorbidity is the most frequent factor associated with adverse events. The biomarkers analyzed do not have a good predictive ability to predict adverse events.</div></div>","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":"42 8","pages":"Pages 420-429"},"PeriodicalIF":2.6,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139014636","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}