Enfermedades infecciosas y microbiologia clinica最新文献_第3页

Una interesante pareja de baile en un inmigrante subsahariano 撒哈拉以南移民的有趣舞伴

IF 2.5 4区医学

Enfermedades infecciosas y microbiologia clinica Pub Date : 2024-06-01 DOI: 10.1016/j.eimc.2023.11.004

Mar Redero Cascón , Inmaculada Izquierdo , Juan Luis Muñoz Bellido , Moncef Belhassen-Garcia

引用次数: 0

Una causa inesperada de miopericarditis en un paciente inmunodeprimido 免疫力低下患者心肌炎的意外病因

IF 2.5 4区医学

Enfermedades infecciosas y microbiologia clinica Pub Date : 2024-06-01 DOI: 10.1016/j.eimc.2024.01.010

Elisa González de Herrero , Victoriano Moreno , María Luisa Martín-Pena , Enrique Ruiz de Gopegui

引用次数: 0

Correlates of one-year mortality among patients living with HIV according to the stratification level of the pharmaceutical care model 根据药物护理模式的分层水平，HIV感染者一年死亡率的相关因素。

IF 2.5 4区医学

Enfermedades infecciosas y microbiologia clinica Pub Date : 2024-06-01 DOI: 10.1016/j.eimc.2023.04.002

Enrique Contreras-Macías , María de las Aguas Robustillo-Cortés , Ramón Morillo-Verdugo

{"title":"Correlates of one-year mortality among patients living with HIV according to the stratification level of the pharmaceutical care model","authors":"Enrique Contreras-Macías , María de las Aguas Robustillo-Cortés , Ramón Morillo-Verdugo","doi":"10.1016/j.eimc.2023.04.002","DOIUrl":"10.1016/j.eimc.2023.04.002","url":null,"abstract":"<div><h3>Objectives</h3><p>The patient living with HIV (PLWH) profile has changed and with it, the importance of patient-oriented pharmaceutical care (PC) has been highlighted, for which the stratification tool of the Capacity-Motivation-Opportunity (CMO) PC model helps us which adapts to the needs of each patient. To assess the true relevance, our main objective is to evaluate the differences of one-year mortality among PLWH stratified according to this model.</p></div><div><h3>Methods</h3><p>A single-center observational analytical survival research study including adult PLWH on antiretroviral therapy<span> (ART) from January-2021 to January-2022 treated at hospital pharmacy outpatient service according to CMO pharmaceutical care model.</span></p></div><div><h3>Results</h3><p><span>A total of 428 patients were included, a median age of 51 years (interquartile range 42–57 year). Overall, the number of patients stratified according to the CMO PC model was 86.2% at level 3, 9.8% at level 2, and 4.0% at level 1. Cox proportional hazard model that included the stratification level was associated with a higher mortality, whose level 1 patients had a 99.7% higher mortality (Hazard ratio</span>  <!-->0.0003; 95%CI: 0.001–0.027).</p></div><div><h3>Conclusions</h3><p>To sum up, mortality of-one year differs when comparing the PC strata of level 1 and non-level 1, although being similar in age and other clinical conditions. This result suggests that the multidimensional stratification tool, included in the CMO PC model, could be used to modulate the patients intensity follow-up and design interventions more tailored to their needs.</p></div>","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":null,"pages":null},"PeriodicalIF":2.5,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41882137","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Relevancia clínica de la codetección viral en lactantes con bronquiolitis por virus respiratorio sincitial 呼吸道合胞病毒支气管炎婴儿合并病毒检测的临床意义

IF 2.5 4区医学

Enfermedades infecciosas y microbiologia clinica Pub Date : 2024-06-01 DOI: 10.1016/j.eimc.2023.04.009

Albert Bernet Sánchez , Alba Bellés Bellés , Mercè García González , Laura Minguell Domingo , Eduard Solé Mir

{"title":"Relevancia clínica de la codetección viral en lactantes con bronquiolitis por virus respiratorio sincitial","authors":"Albert Bernet Sánchez , Alba Bellés Bellés , Mercè García González , Laura Minguell Domingo , Eduard Solé Mir","doi":"10.1016/j.eimc.2023.04.009","DOIUrl":"10.1016/j.eimc.2023.04.009","url":null,"abstract":"<div><h3>Introduction</h3><p>Respiratory syncytial virus (RSV) is the main cause of severe bronchiolitis, especially in infants. The aim of this study is to assess whether codetection of RSV and other respiratory viruses could affect the severity of this infection comparing with unique RSV detection.</p></div><div><h3>Methods</h3><p>A prospective study from 2016 to 2019 including children under 2 years who were admitted in the Emergency Service of the Hospital Universitari Arnau de Vilanova de Lleida (Spain) was performed. Nasopharyngeal samples from all patients were sent to the laboratory for RSV real-time PCR detection (GeneXpert®). A multiplex PCR that detects other respiratory viruses was done in all RSV-positive samples. Patients’ medical records were checked to collect clinical data (hospital length of stay, BROSJOD score, ICU admission, need for ventilatory support or transfer to a reference hospital). Patients were divided in 2 groups: infants with unique RSV detection and infants with viral codetection. Bivariant analyses were performed to analyze the data obtained.</p></div><div><h3>Results</h3><p>During the period of study 437 RSV bronchiolitis were diagnosed. In 199 of them (177/437; 45.5%) another respiratory virus was detected concomitantly. Bivariant analyses do not show statistically significant differences between both groups.</p></div><div><h3>Conclusions</h3><p>Viral codetection in infants with RSV bronchiolitis is frequent. However, it does not seems to affect the severity of this infection.</p></div>","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":null,"pages":null},"PeriodicalIF":2.5,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121298669","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Investigating outbreaks in neonatal intensive care units: A crucial battle in the cradle of care 调查新生儿重症监护室的疫情爆发：护理摇篮中的一场关键战役

IF 2.5 4区医学

Enfermedades infecciosas y microbiologia clinica Pub Date : 2024-06-01 DOI: 10.1016/j.eimc.2024.03.004

Esther Calbo , Laura Gisbert , Maria López-Sánchez

引用次数: 0

Análisis transversal de una cohorte de personas de más de 65 años que viven con VIH 对 65 岁以上艾滋病毒感染者队列的横断面分析

IF 2.5 4区医学

Enfermedades infecciosas y microbiologia clinica Pub Date : 2024-06-01 DOI: 10.1016/j.eimc.2024.01.008

Iván Fernández-Castro, Clara Casar-Cocheteux, Hadrian Pernas-Pardavila, Elena Losada-Arias, Antonio Antela

{"title":"Análisis transversal de una cohorte de personas de más de 65 años que viven con VIH","authors":"Iván Fernández-Castro, Clara Casar-Cocheteux, Hadrian Pernas-Pardavila, Elena Losada-Arias, Antonio Antela","doi":"10.1016/j.eimc.2024.01.008","DOIUrl":"10.1016/j.eimc.2024.01.008","url":null,"abstract":"<div><h3>Introduction</h3><p>This study aims to describe and analyze the characteristics of aged people who are living with HIV (APHIV) and evaluate their association on the comorbidities they currently have.</p></div><div><h3>Methods</h3><p>Cross-sectional analysis of APHIV under active follow-up at the Infectious Diseases Unit of the University Clinical Hospital of Santiago de Compostela. Demographic and clinical data were analyzed, along with their association with the development of comorbidities in this population. A correlation and multiple linear regression analysis were performed for this purpose.</p></div><div><h3>Results</h3><p>Eighty-five APHIV, 65 males and 20 females, with an average age of 69 years (IQR: 8) and a duration of living with HIV of 17 years (SD: 7), were studied. 41% of them had their initial diagnosis with AIDS. The most common comorbidities are hypertension and dyslipidemia in 55% and 52%, respectively. 40% of APHIV take at least 5 medications. 35% have received more than 5 lines of antiretroviral treatment. At the time of analysis, all APHIV have an undetectable viral load. No significant association was observed between the number of comorbidities and various characteristics of APHIV; however, a weak correlation was noted among age, the cumulative number of antiretroviral treatments received throughout their lives, and the number of comorbidities.</p></div><div><h3>Conclusions</h3><p>This analysis highlights the substantial burden of comorbidities and polypharmacy experienced by APHIV. Further studies are needed to better understand the characteristics and variables influencing their development.</p></div>","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":null,"pages":null},"PeriodicalIF":2.5,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139988205","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Brote nosocomial causado por Serratia marcescens en una unidad de cuidados intensivos neonatal de un hospital regional. Análisis y propuestas de mejora 一家地区医院的新生儿重症监护室爆发了由肉豆蔻沙雷氏菌引起的医院内感染。分析和改进建议

IF 2.5 4区医学

Enfermedades infecciosas y microbiologia clinica Pub Date : 2024-06-01 DOI: 10.1016/j.eimc.2023.04.001

María Liébana-Rodríguez , Inés Portillo-Calderón , María Amelia Fernández-Sierra , Mercedes Delgado-Valverde , Lina Martín-Hita , José Gutiérrez-Fernández

{"title":"Brote nosocomial causado por Serratia marcescens en una unidad de cuidados intensivos neonatal de un hospital regional. Análisis y propuestas de mejora","authors":"María Liébana-Rodríguez , Inés Portillo-Calderón , María Amelia Fernández-Sierra , Mercedes Delgado-Valverde , Lina Martín-Hita , José Gutiérrez-Fernández","doi":"10.1016/j.eimc.2023.04.001","DOIUrl":"10.1016/j.eimc.2023.04.001","url":null,"abstract":"<div><h3>Objectives</h3><p><em>Serratia marcescens</em> may cause nosocomial outbreaks in neonatal intensive care units. We describe an outbreak of <em>Serratia marcescens</em> in a neonatal intensive care unit and propose additional prevention and control recommendations.</p></div><div><h3>Methods</h3><p>Between March 2019 and January 2020, samples were taken from patients in the neonatal intensive care unit (rectal, pharyngeal, axillary and other locations) and from 15 taps and their sinks. Control measures were implemented including thorough cleaning of incubators, health education to staff and neonates’ relatives, and use of single-dose containers. PFGE was performed in 19 isolates from patients and in 5 environmental samples.</p></div><div><h3>Results</h3><p>From the first case in March 2019 to the detection of the outbreak, a month elapsed. Finally, 20 patients were infected and 5 colonized. Eighty percent of infected neonates had conjunctivitis, 25% bacteremia, 15% pneumonia, 5% wound infection, and 5% urinary tract infection. Six neonates had 2 foci of infection. Among the 19 isolates studied, 18 presented the same pulsotype and only one of the isolates from the sinkhole showed a clonal relationship with those of the outbreak. Initial measures established were ineffective to control the outbreak and were implemented with exhaustive cleaning, use of individual eye drops, environmental sampling and changing sinks.</p></div><div><h3>Conclusion</h3><p>This outbreak presented a high number of neonates affected due to its late detection and torpid evolution. The microorganisms isolated from the neonates were related to an environmental isolate. Additional prevention and control measures are proposed, including routine weekly microbiological sampling.</p></div>","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":null,"pages":null},"PeriodicalIF":2.5,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116411222","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A case of unresolved skin lesion in a cobbler 一个鞋匠身上未治愈的皮损病例

IF 2.5 4区医学

Enfermedades infecciosas y microbiologia clinica Pub Date : 2024-06-01 DOI: 10.1016/j.eimc.2023.12.002

Ali Mert , Abdurrahman Kaya , Sibel Yildiz Kaya

引用次数: 0

Celulitis craneo-facial con pericondritis y otitis externa profesional, a propósito de un caso 颅面蜂窝织炎伴软骨周炎和职业性外耳道炎，病例报告

IF 2.5 4区医学

Enfermedades infecciosas y microbiologia clinica Pub Date : 2024-06-01 DOI: 10.1016/j.eimc.2024.02.008

Eloy Sempere Moreno, Santos Ibáñez Barceló, Marta Montero Alonso

引用次数: 0

Espiroquetosis intestinal humana como entidad asociada a infecciones de transmisión sexual 作为性传播感染相关实体的人类肠道螺旋体病

IF 2.5 4区医学

Enfermedades infecciosas y microbiologia clinica Pub Date : 2024-05-01 DOI: 10.1016/j.eimc.2023.03.001

Alejandro De Gea-Grela , Alfredo Maldonado-Barrueco , Clara Cabañuz , Mariana Díaz-Almiron , Alicia Rico , Guillermo Ruíz-Carrascoso , Maria Elena Palacios , Eduardo Martín-Arranz , Raquel Escudero-Nieto , José I Bernardino

{"title":"Espiroquetosis intestinal humana como entidad asociada a infecciones de transmisión sexual","authors":"Alejandro De Gea-Grela , Alfredo Maldonado-Barrueco , Clara Cabañuz , Mariana Díaz-Almiron , Alicia Rico , Guillermo Ruíz-Carrascoso , Maria Elena Palacios , Eduardo Martín-Arranz , Raquel Escudero-Nieto , José I Bernardino","doi":"10.1016/j.eimc.2023.03.001","DOIUrl":"10.1016/j.eimc.2023.03.001","url":null,"abstract":"<div><h3>Introduction</h3><p>Human intestinal spirochetosis (HIE) is a poorly studied clinical entity with variable clinical manifestations. However, in recent years it has gained special relevance because an increasing number of cases have been described in people living with HIV (PWH) and in patients with a history of sexually transmitted infections (STI) or immunosuppression.</p></div><div><h3>Methods</h3><p>retrospective review of all HIE cases identified in a tertiary level hospital (Hospital Universitario la Paz, Madrid) between 2014-2021.</p></div><div><h3>Results</h3><p>36 cases of HIE were identified. Most cases corresponded to males (94%) with a median age of 45 years. 10 patients (29.4%) were PWH and 20 (56%) were men who had sex with men. Although the clinical manifestations were very heterogeneous, the most frequent was chronic diarrhea (47%), and up to 25% of the subjects had clinical proctitis. 39% percent of patients had been diagnosed with an STI in the previous two years, this characteristic being more frequent in PWH (90% vs 28%; p < 0.01) than in patients without HIV infection. The STI most frequently associated with a diagnosis of HIE was syphilis (31%).</p></div><div><h3>Conclusión</h3><p>HIE is frequently diagnosed with other STIs and affects mostly men who have sex with men, which supports that this entity could be considered as a new STI.</p></div>","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":null,"pages":null},"PeriodicalIF":2.5,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115242072","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0