Enfermedades infecciosas y microbiologia clinica最新文献

{"title":"Aspergilosis invasiva secundaria a corticoterapia","authors":"Sara Miguel Álvarez, Maravillas Carralón González, Juncal Pérez Somarriba, Vicente Estrada Pérez","doi":"10.1016/j.eimc.2024.12.015","DOIUrl":"10.1016/j.eimc.2024.12.015","url":null,"abstract":"","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":"43 4","pages":"Pages 234-235"},"PeriodicalIF":2.6,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143748394","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Neonatal sepsis: Epidemiology and comparison between preterm and term newborns","authors":"Eduardo Rubio-Mora,&nbsp;Iván Bloise-Sánchez,&nbsp;Inmaculada Quiles-Melero,&nbsp;Juana Cacho-Calvo,&nbsp;Emilio Cendejas-Bueno","doi":"10.1016/j.eimc.2024.07.010","DOIUrl":"10.1016/j.eimc.2024.07.010","url":null,"abstract":"<div><h3>Introduction</h3><div>Neonatal sepsis is a severe clinical syndrome that continues to be a common and significant health care burden. Knowledge of the local epidemiology allows for a better empirical treatment and improves morbidity and mortality. The aim of this study was to determine the prevalence, epidemiology, and etiology of blood culture-proven sepsis in neonates and to determine whether there are differences between preterm and term newborns.</div></div><div><h3>Methods</h3><div>A retrospective study was carried out in a tertiary hospital in Madrid, Spain, during 2021, including 1443 patients at risk of developing sepsis.</div></div><div><h3>Results</h3><div>The majority of sepsis episodes occurred in preterm newborns (64.81%) and most of them were very low birth weight infants (74.29%). Late-onset sepsis represented 94.92% of all the episodes reported with an incidence of 11.4 (95% CI 8.8–14.8) per 1000 live newborns. Early onset sepsis incidence was 0.6 (95% CI 0.2–1.8) per 1000 live newborns. Coagulase-negative staphylococci took the first place as causative agents of sepsis (66.10%), causing in all the episodes late onset catheter-related bloodstream infection. When the newborns who developed sepsis were compared with those who did not developed sepsis, the presence of venous/arterial access device was significantly associated with sepsis in both preterm (odds ratio (OR) 8.12, 95% CI 0.47–141.40) and term newborns (OR 16.58, 95% CI 1.00–275.20). Recent surgery was nevertheless the main risk factor in term newborns (OR 45.29, 95% CI 13.70–149.70). Among those patients who developed sepsis, no differences between preterm and term newborns were found regarding time onset, mechanism of transmission, etiological agents, and mortality. A 100% of the preterm and 42.11% of the term newborns presented two or more risk factors. The mortality rate observed here has been 1.85% (95% CI 0.33–9.77%).</div></div><div><h3>Conclusion</h3><div>The main risk factors for sepsis were venous/arterial access device (for both preterm and term newborns) and recent surgery (term newborns). Prematurity and being a catheter carrier were strongly associated with late-onset neonatal sepsis, mainly due to coagulase-negative staphylococci. The mortality rate was lower than that observed in other high-income countries.</div></div>","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":"43 4","pages":"Pages 197-204"},"PeriodicalIF":2.6,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143748215","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bartonella spp. infection in a person with HIV and advanced immunosuppression: A case report","authors":"Roser Navarro-Soler,&nbsp;Juan Martín-Torres,&nbsp;Anatolio Alonso-Crespo,&nbsp;David Rial-Crestelo","doi":"10.1016/j.eimc.2024.12.009","DOIUrl":"10.1016/j.eimc.2024.12.009","url":null,"abstract":"","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":"43 4","pages":"Pages 232-233"},"PeriodicalIF":2.6,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143748395","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Invasive pneumococcal disease in a tertiary hospital in Madrid: are we using pneumococcal vaccine correctly?","authors":"María Isabel Serrano-Tomás ,&nbsp;Margarita Cabello ,&nbsp;Paloma Moreno-Nuñez ,&nbsp;Juan Carlos Sanz ,&nbsp;Rafael Cantón ,&nbsp;Ana María Sánchez-Díaz","doi":"10.1016/j.eimc.2024.08.006","DOIUrl":"10.1016/j.eimc.2024.08.006","url":null,"abstract":"<div><h3>Introduction</h3><div>Invasive pneumococcal disease (IPD) is of concern. We describe the epidemiology and assess the vaccination schedule adequacy of IPD episodes (2019–2021) in northern Madrid.</div></div><div><h3>Methods</h3><div>Clinical, laboratory and vaccination data were collected from clinical/epidemiological records. Antimicrobial susceptibility testing was performed according to EUCAST and serotyping by Pneumotest-agglutination/Quellung.</div></div><div><h3>Results</h3><div>IPD was identified in 103 patients (71 [IQR 23.5] year-old; 50.4% males), 85.4% associated with bacteremia and a high mortality rate (19.4%). Serotypes 8 (29.9%), 3 and 22F (8% each) were dominant (45.9%), all antibiotic-susceptible. β-Lactams increased MICs and macrolide resistance were mainly linked to serotypes 19A, 23F, 24F, 6C, and 15A. Only 10.5% of adults eligible for vaccination had an adequate vaccine regimen before IPD being 40% due to nonvaccine-preventable serotypes (13, 23B, 24F, 31).</div></div><div><h3>Conclusion</h3><div>IPD episodes were dominated by antibiotic-susceptible ST8 and frequently occurred in adults at risk. Despite recommendations, vaccination adherence rates were very low.</div></div>","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":"43 4","pages":"Pages 210-214"},"PeriodicalIF":2.6,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143748576","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of Zhuhai DL Biotech's BT24 automated blood culture system","authors":"Blanca Carrasco,&nbsp;Elena Hidalgo,&nbsp;Gloria Zaragoza,&nbsp;Juan-Ignacio Alós","doi":"10.1016/j.eimc.2024.07.003","DOIUrl":"10.1016/j.eimc.2024.07.003","url":null,"abstract":"<div><h3>Introduction</h3><div>For the microbiological diagnosis of bacteremia and fungemia, it is essential to use automated blood culture systems that guarantee good performance in the detection of microorganisms.</div><div>We evaluated the BT24 system for blood cultures (BCs) by comparing it with the BACTEC™ FX system in detection of positive spiked BCs and bottles, subsequent growth of the microorganism, and time to detection (TTD).</div></div><div><h3>Methods</h3><div>The parallel analysis of both systems was performed with 160 strains of 31 different species, each inoculated under the same conditions and simultaneously in six BC bottles.</div><div>The Chi-square test was used for comparison per BC and per bottle detection. Wilcoxon test and Student's <em>t</em>-test were used for comparison of TTDs.</div></div><div><h3>Results</h3><div>Overall, the following BC (aerobic bottle<!--> <!-->+<!--> <!-->anaerobic bottle) were detected as positive: 160/160 (100%) in BACTEC FX and 158/160 (98.7%) in BT24 (<em>p</em> <!-->=<!--> <!-->0.31). Furthermore, the following pediatric BCs (1 single bottle, aerobic) were also detected: 159/160 (99.4%) in BACTEC FX and 156/160 (97.5%) in BT24 (<em>p</em> <!-->=<!--> <!-->0.17).</div><div>TTDs were longer with BT24 system than with BACTEC FX system, especially for <em>Staphylococcus aureus</em> strains.</div></div><div><h3>Conclusions</h3><div>We consider the BT24 system with good performance and specificity comparable to the reference system, but inferior in TTD.</div></div>","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":"43 4","pages":"Pages 188-192"},"PeriodicalIF":2.6,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143748213","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lesión genital inusual simulando carcinoma epidermoide: un desafío diagnóstico","authors":"Marta Cebolla-Verdugo ,&nbsp;David Moyano-Bueno ,&nbsp;Álvaro Prados-Carmona ,&nbsp;Ricardo Ruiz-Villaverde","doi":"10.1016/j.eimc.2024.07.012","DOIUrl":"10.1016/j.eimc.2024.07.012","url":null,"abstract":"","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":"43 4","pages":"Pages 229-230"},"PeriodicalIF":2.6,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143748211","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dientamoeba fragilis: An emerging pathogen","authors":"Candela Menéndez Fernández-Miranda ,&nbsp;Jonathan Fernández-Suárez ,&nbsp;Alicia García Pérez ,&nbsp;José Antonio Boga ,&nbsp;Mercedes Rodríguez-Pérez ,&nbsp;Azucena Rodríguez-Guardado","doi":"10.1016/j.eimc.2024.08.015","DOIUrl":"10.1016/j.eimc.2024.08.015","url":null,"abstract":"<div><div><em>Dientamoeba fragilis</em> is a protozoan of the gastrointestinal tract, very prevalent in our environment and responsible for diverse clinical symptoms mainly abdominal pain, diarrhoea and eosinophilia, although some infected patients are asymptomatic. Since the first description just a century ago, there are many unanswered questions: its different morphologies and the role of each of them, its actual prevalence, the mode of transmission, its pathogenicity, or the treatment of choice, continue to be source of controversy. Risk factors associated with infection by <em>D. fragilis</em> are: contact with children, residence in a rural area, and co-infection by <em>Enterobius vermicularis</em>. New molecular diagnostic techniques in the form of commercial multi-diagnostic panels are now considered first choice techniques. Paromomycin show higher cure rates, than metronidazole.</div></div>","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":"43 4","pages":"Pages 219-226"},"PeriodicalIF":2.6,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143748578","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Violaceous plaque in an immunosuppressed patient's leg","authors":"Rodolfo David Palacios-Diaz ,&nbsp;Iván Rienda-Martínez ,&nbsp;Antonio Sahuquillo-Torralba ,&nbsp;Rafael Botella-Estrada","doi":"10.1016/j.eimc.2024.07.009","DOIUrl":"10.1016/j.eimc.2024.07.009","url":null,"abstract":"","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":"43 4","pages":"Pages 227-228"},"PeriodicalIF":2.6,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143748209","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Macrolide and fluoroquinolone resistance in Mycoplasma genitalium in the Northwestern region of Spain, 2019–2022","authors":"Antonio Moreno-Flores ,&nbsp;María Domínguez-Landesa ,&nbsp;Laura Sante-Fernández ,&nbsp;María José Gude-González","doi":"10.1016/j.eimc.2024.10.006","DOIUrl":"10.1016/j.eimc.2024.10.006","url":null,"abstract":"","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":"43 4","pages":"Pages 231-232"},"PeriodicalIF":2.6,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143748210","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Experiencia en Canarias de una estrategia de cribado de VIH en los servicios de urgencias hospitalarios: resultados del programa «Deja tu huella»","authors":"Nayra Cabrera-González ,&nbsp;José M. Pavón-Monzó ,&nbsp;Araceli Hernández-Betancor ,&nbsp;Isidro Báez-Ramos","doi":"10.1016/j.eimc.2024.12.020","DOIUrl":"10.1016/j.eimc.2024.12.020","url":null,"abstract":"","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":"43 4","pages":"Pages 237-238"},"PeriodicalIF":2.6,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143748212","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}