Enfermedades infecciosas y microbiologia clinica最新文献_第4页

Trend of pediatric leprosy in an endemic area in Northeast of Brazil, 2008–2018 2008-2018年巴西东北部流行区小儿麻风病的发展趋势

IF 2.6 4区医学

Enfermedades infecciosas y microbiologia clinica Pub Date : 2024-10-01 DOI: 10.1016/j.eimc.2023.06.009

{"title":"Trend of pediatric leprosy in an endemic area in Northeast of Brazil, 2008–2018","authors":"","doi":"10.1016/j.eimc.2023.06.009","DOIUrl":"10.1016/j.eimc.2023.06.009","url":null,"abstract":"<div><h3>Background</h3><div>The incidence of leprosy in children is an important indicator of the disease's tendency in the general population and suggests intense circulation and transmission of <span><span>Mycobacterium leprae</span></span>.</div></div><div><h3>Objectives</h3><div>To describe the clinical, epidemiological characteristics and temporal dynamics of leprosy cases in children under 15 years of age from 2008 to 2018 in an endemic municipality.</div></div><div><h3>Methods</h3><div>A descriptive study with an analytical approach was carried out with data from leprosy cases registered in the Brazilian Information System on Notifiable Diseases for the municipality of Cabo de Santo Agostinho, Pernambuco, Brazil.</div></div><div><h3>Results</h3><div>Between 2008 and 2018, 112 new cases of leprosy were registered. Most cases were classified as paucibacillary leprosy and occurred in children living in urban areas. There was no significant difference in the incidence of leprosy during the study period. Only 4.5% of the sample presented reactional episodes, but a high number of cases were not evaluated for the occurrence of reactions.</div></div><div><h3>Conclusions</h3><div>The findings of this study show a high incidence of paucibacillary leprosy in children and adolescents, which reveals active transmission in the community and failures in the detection of new multibacillary cases among adults. Children between 10 and 14 years old are more vulnerable to <em>M. leprae</em> infection and mainly develop paucibacillary leprosy.</div></div>","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":"42 8","pages":"Pages 401-405"},"PeriodicalIF":2.6,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134411699","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Atypical bullae in hands and trunk: An unusual suspect 手部和躯干的非典型鼓包不寻常的嫌疑人

IF 2.6 4区医学

Enfermedades infecciosas y microbiologia clinica Pub Date : 2024-10-01 DOI: 10.1016/j.eimc.2023.12.010

引用次数: 0

Spatial analysis for risk assessment of dengue in Spain 西班牙登革热风险评估的空间分析

IF 2.6 4区医学

Enfermedades infecciosas y microbiologia clinica Pub Date : 2024-10-01 DOI: 10.1016/j.eimc.2023.06.010

{"title":"Spatial analysis for risk assessment of dengue in Spain","authors":"","doi":"10.1016/j.eimc.2023.06.010","DOIUrl":"10.1016/j.eimc.2023.06.010","url":null,"abstract":"<div><h3>Introduction</h3><div>The establishment of <em>Aedes albopictus</em> in new areas in Europe has changed the risk of local dengue transmission represented by imported human cases. The risk of transmission is determined by the distribution of travelers arriving from dengue-endemic areas and the distribution of <em>Ae. albopictus</em> as potential vectors of dengue in Spain.</div></div><div><h3>Methods</h3><div>Environmental, entomological, epidemiological, demographic, tourism and travel data were analyzed to produce a series of maps to represent: the distribution of <em>Ae. albopictus</em> across municipalities; the risk of expansion of <em>Ae. albopictus</em> based on a species distribution model; the calculated index of travelers from dengue-endemic areas (IDVZE) per province; the percentage contribution of each municipality to the total number of cases in Spain. The maps were then added using map algebra, to profile the spatial risk of autochthonous dengue in Spain at a municipal level from 2016 to 2018.</div></div><div><h3>Results</h3><div><em>Ae. albopictus</em> was detected in 983 municipalities. The calculated IDVZE varied from 0.23 to 10.38, with the highest IDVZE observed in Madrid. The overall risk of autochthonous cases oscillated between 0.234 and 115, with the very high risk and high risk areas detected in the Mediterranean region, mainly in the Levantine coast and some parts of the Balearic Islands. Most of the interior of the peninsula was characterized as low risk.</div></div><div><h3>Conclusion</h3><div>Prevention and control measures to mitigate the risk of autochthonous dengue should be prioritized for municipalities in the high risk areas integrating early detection of imported dengue cases and vector control.</div></div>","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":"42 8","pages":"Pages 406-413"},"PeriodicalIF":2.6,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134935912","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Consideraciones sobre los comentarios a las recomendaciones del Comité Español del Antibiograma (COESANT) para la realización de los informes de sensibilidad antibiótica acumulada 对西班牙抗生素图谱委员会（COESANT）关于累积抗菌药物药敏性报告建议的意见的考虑

IF 2.6 4区医学

Enfermedades infecciosas y microbiologia clinica Pub Date : 2024-10-01 DOI: 10.1016/j.eimc.2024.03.011

引用次数: 0

Addressing catheter lock therapy: Does heparin reduce the bioactivity of dalbavancin when together in solution during freezing? 解决导管锁定疗法：肝素与达巴万星一起在溶液中冷冻时是否会降低达巴万星的生物活性？

IF 2.6 4区医学

Enfermedades infecciosas y microbiologia clinica Pub Date : 2024-10-01 DOI: 10.1016/j.eimc.2024.02.005

{"title":"Addressing catheter lock therapy: Does heparin reduce the bioactivity of dalbavancin when together in solution during freezing?","authors":"","doi":"10.1016/j.eimc.2024.02.005","DOIUrl":"10.1016/j.eimc.2024.02.005","url":null,"abstract":"<div><h3>Introduction</h3><div>The possible use of dalbavancin as a catheter lock solution was previously demonstrated by our study group. However, it was needed to assess whether heparin could affect dalbavancin bioactivity during freezing storage.</div></div><div><h3>Methods</h3><div>We tested the bioactivity of a dalbavancin+heparin (DH) vs. dalbavancin (<em>D</em><span>) against Staphylococcal biofilms comparing DH median value of cfu counts and metabolic activity with that obtained for </span><em>D</em> before and during storage under freezing up to 6 months.</div></div><div><h3>Results</h3><div>Despite there was a slight decrease in the median percentage reduction of metabolic activity at month 3 in <span><span>Staphylococcus epidermidis</span></span><span> between DH and </span><em>D</em> (97.6 vs. 100, <em>p</em>  <!-->0.037), considering the clinical criteria, no significant reduction in any of the variables tested was observed at the end of the experiment between <em>D</em> and DH solutions.</div></div><div><h3>Conclusion</h3><div>The addition of heparin to a dalbavancin lock solution did not affect its bioactivity against staphylococcal biofilms irrespective of its preservation time under freezing.</div></div>","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":"42 8","pages":"Pages 435-438"},"PeriodicalIF":2.6,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140181810","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

¿Cómo podemos optimizar el abordaje diagnóstico y terapéutico de la neumonía? Recomendaciones basadas en una opinión de expertos 如何优化肺炎的诊断和治疗方法？基于专家意见的建议

IF 2.6 4区医学

Enfermedades infecciosas y microbiologia clinica Pub Date : 2024-10-01 DOI: 10.1016/j.eimc.2024.06.003

Mario Fernández-Ruiz , Juan José Castón , José Luis del Pozo , Jordi Carratalà , Jesús Fortún , Miguel Salavert , Julián Torre-Cisneros , José María Aguado , en representación de los miembros del Grupo OPENIN (Optimización de procesos clínicos para el diagnóstico y tratamiento de infecciones)

{"title":"¿Cómo podemos optimizar el abordaje diagnóstico y terapéutico de la neumonía? Recomendaciones basadas en una opinión de expertos","authors":"Mario Fernández-Ruiz , Juan José Castón , José Luis del Pozo , Jordi Carratalà , Jesús Fortún , Miguel Salavert , Julián Torre-Cisneros , José María Aguado , en representación de los miembros del Grupo OPENIN (Optimización de procesos clínicos para el diagnóstico y tratamiento de infecciones)","doi":"10.1016/j.eimc.2024.06.003","DOIUrl":"10.1016/j.eimc.2024.06.003","url":null,"abstract":"<div><div>Pneumonia continues to be one of the most frequent infectious syndromes and a relevant cause of death and health resources utilization. The OPENIN <em>(Optimización de procesos clínicos para el diagnóstico y tratamiento de infecciones)</em> Group is composed of infectious diseases specialists and microbiologists and aims at generating recommendations that can contribute to improve the approach to processes with high impact on the health system. Such task relies on a critical review of the available scientific evidence. The first group meeting (held in October 2023) aimed at answering the following questions: Can we optimize the syndromic and microbiological diagnosis of pneumonia? Is it feasible to safely shorten the length of antibiotic therapy? And, is there any role for the immunomodulatory strategies based on the adjuvant use of steroids, macrolides or immunoglobulins? The present review summarizes the literature reviewed for that meeting and offers a series of expert recommendations.</div></div>","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":"42 8","pages":"Pages 442-452"},"PeriodicalIF":2.6,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141700100","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Bacteriemia por Elizabethkingia anophelis en paciente con neumonía 一名肺炎患者的伊丽莎白金格氏 anophelis 菌血症

IF 2.6 4区医学

Enfermedades infecciosas y microbiologia clinica Pub Date : 2024-08-01 DOI: 10.1016/j.eimc.2024.03.015

引用次数: 0

Tubercular longitudinally extensive transverse myelitis: An unmissable zebra grazing the Indian medical field 结核性纵向广泛横贯性脊髓炎：印度医学界一匹不可忽视的斑马

IF 2.6 4区医学

Enfermedades infecciosas y microbiologia clinica Pub Date : 2024-08-01 DOI: 10.1016/j.eimc.2024.04.002

引用次数: 0

Caracterización de la reinfección de prótesis articular tras recambio en 2 tiempos (infección de la prótesis del 2.o tiempo). Un estudio multicéntrico 二期假体置换（二期假体感染）后关节置换术后再感染的特征。多中心研究

IF 2.6 4区医学

Enfermedades infecciosas y microbiologia clinica Pub Date : 2024-08-01 DOI: 10.1016/j.eimc.2023.05.003

{"title":"Caracterización de la reinfección de prótesis articular tras recambio en 2 tiempos (infección de la prótesis del 2.o tiempo). Un estudio multicéntrico","authors":"","doi":"10.1016/j.eimc.2023.05.003","DOIUrl":"10.1016/j.eimc.2023.05.003","url":null,"abstract":"<div><h3>Introduction</h3><p>Two-stage exchange is the gold standard in the surgical management of prosthetic joint infection (PJI). However, perioperative reinfections (RePJI) can occur to newly inserted prosthesis, which highlights the importance of an adequate antibiotic prophylaxis, although there is scarce evidence in this field. Our objective was to evaluate the characteristics of RePJI, its prognosis and the antibiotic prophylaxis that is commonly used in second-stage surgery.</p></div><div><h3>Methods</h3><p>Multicentric retrospective observational study in Spanish hospitals including patients with RePJI between 2009 and 2018.</p></div><div><h3>Results</h3><p>We included 92 patients with RePJI from 12 hospitals. The most frequent isolated microorganism was <em>Staphylococcus epidermidis</em> in 35 cases (38.5%); 61.1% of staphylococci were methiciliin-resistant. In 12 cases (13%), the same microorganism causing the primary PJI was isolated in RePJI. When comparing with the microbiology of primary PJI, there were more cases caused by Gram-negative bacteria (the most frequent was <em>Pseudomonas</em> spp.) and less by Gram-positive bacteria. Failure occurred in 69 cases (75%). There were 43 different courses of antibiotic prophylaxis after the second-stage surgery; the most frequent was a unique preoperative cefazolin dose, but most patients received prophylaxis before and after the second-stage surgery (61 cases).</p></div><div><h3>Conclusions</h3><p>The most frequent microorganisms in RePJI are coagulase-negative staphylococci, although Gram-negative bacteria, especially <em>Pseudomonas</em> spp. are also common. There is a significant heterogeneity in antibiotic prophylaxis for a second-stage surgery. ReIPJI treatment has a high failure rate.</p></div>","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":"42 7","pages":"Pages 354-360"},"PeriodicalIF":2.6,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123490424","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Respuesta a la carta sobre las limitaciones del diagnóstico de meningitis tuberculosa 回复关于结核性脑膜炎诊断局限性的信件

IF 2.6 4区医学

Enfermedades infecciosas y microbiologia clinica Pub Date : 2024-08-01 DOI: 10.1016/j.eimc.2024.04.007

Lluïsa Guillem , Miguel Santín

引用次数: 0