Enfermedades infecciosas y microbiologia clinica最新文献_第5页

Ecografía clínica: presente y futuro en enfermedades infecciosas 临床超声：传染病的现状与未来

IF 2.6 4区医学

Enfermedades infecciosas y microbiologia clinica Pub Date : 2024-08-01 DOI: 10.1016/j.eimc.2024.01.007

引用次数: 0

Enhancing pneumococcal bacteraemia diagnosis: A comparative assessment of culture-independent assays (MALDI–TOF–MS Sepsityper® module and a lateral flow inmunochromatography test) 加强肺炎球菌菌血症诊断：独立于培养的检测方法（MALDI-TOF-MS Sepsityper® 模块和侧流免疫层析检测）的比较评估

IF 2.6 4区医学

Enfermedades infecciosas y microbiologia clinica Pub Date : 2024-08-01 DOI: 10.1016/j.eimc.2024.02.001

{"title":"Enhancing pneumococcal bacteraemia diagnosis: A comparative assessment of culture-independent assays (MALDI–TOF–MS Sepsityper® module and a lateral flow inmunochromatography test)","authors":"","doi":"10.1016/j.eimc.2024.02.001","DOIUrl":"10.1016/j.eimc.2024.02.001","url":null,"abstract":"<div><h3>Introduction</h3><p>Pneumococcal bacteraemia is a major contributor to global morbidity and mortality. Traditional culture-based methods lack sensitivity and are time-consuming. This study aimed to assess the effectiveness of two culture-independent assays, the MALDI–TOF–MS Sepsityper® module and the lateral flow inmunochromatography test (LFICT) with the Standard F® <em>Streptococcus pneumoniae</em>, directly from positive blood culture (BC) bottles.</p></div><div><h3>Methods</h3><p>A prospective study was conducted from December 2021 to July 2022. For all BC positives for <span><span>S. pneumoniae</span></span> a double centrifugation protocol was implemented. The resulting pellet was subsequently processed using both techniques.</p></div><div><h3>Results</h3><p>The LFICT showed exceptional performance with 100% sensitivity and specificity, outperforming the MALDI–TOF–MS Sepsityper® module, which achieved 85.2% sensitivity and 100% specificity. Nevertheless, the combination of these assays offers a robust and comprehensive approach to diagnosis.</p></div><div><h3>Conclusions</h3><p>The simultaneous use of both techniques offers a promising alternative that can be integrated into routine practices directly from BC samples.</p></div>","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":"42 7","pages":"Pages 377-379"},"PeriodicalIF":2.6,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140126947","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparación de medios de cultivo para la detección de Legionella spp. en muestras de agua sanitaria: adaptación a la norma ISO 11731:2017 用于检测卫生水样中军团菌属的培养基比较：ISO 11731:2017 适应版

IF 2.6 4区医学

Enfermedades infecciosas y microbiologia clinica Pub Date : 2024-08-01 DOI: 10.1016/j.eimc.2024.03.013

{"title":"Comparación de medios de cultivo para la detección de Legionella spp. en muestras de agua sanitaria: adaptación a la norma ISO 11731:2017","authors":"","doi":"10.1016/j.eimc.2024.03.013","DOIUrl":"10.1016/j.eimc.2024.03.013","url":null,"abstract":"<div><h3>Introduction</h3><p>Water sample culturing is the reference method to detect <em>Legionella</em> spp. in sanitary facilities. Until 2017, UNE-EN ISO 11731 only included the GVPC medium, which inhibits interfering microbiota but hinders the growth of <em>Legionella</em> spp. To improve its recovery, the new standard incorporates the BCYE medium into the working protocol.</p></div><div><h3>Methods</h3><p>We inoculated 1,306 sanitary water samples onto BCYE and GVPC according to an accredited internal procedure. We compared the number of cfu/L of <em>Legionella</em> spp. detected in both media.</p></div><div><h3>Results</h3><p>The median in BCYE was 2,000cfu/L higher than in GVPC (p=0.000). In the presence of high amounts of interfering microbiota, both media were similar; in the absence or low interfering microbiota BCYE was four times more sensitive than GVPC (p=0.000).</p></div><div><h3>Conclusion</h3><p>Including BCYE in the analysis of sanitary water significantly improves the recovery of <em>Legionella</em> spp. in low contaminated samples.</p></div>","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":"42 7","pages":"Pages 373-376"},"PeriodicalIF":2.6,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140768978","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Intertrigo inguinal: ¿infeccioso o inflamatorio? 腹股沟间肌：是损伤性还是炎症性？

IF 2.6 4区医学

Enfermedades infecciosas y microbiologia clinica Pub Date : 2024-08-01 DOI: 10.1016/j.eimc.2023.12.007

引用次数: 0

Resumen ejecutivo de las Guías Española de Diagnóstico y Manejo de Enfermedades Febriles Importadas de la Sociedad Española de Medicina Tropical y Salud Internacional (SEMTSI), el Grupo de Patología Importada de la Sociedad Española de Enfermedades Infecciosas y microbiología clínica (GEPI-SEIMC), la Sociedad Española de Medicina de Familia y Comunitaria (SEMFYC), la Sociedad Española de Médicos de Atención Primaria (SEMERGEN) y la Sociedad Española de Medicina de Urgencias y Emergencias (SEMES) 西班牙热带医学和国际健康学会 (SEMTSI)、西班牙传染病和临床微生物学学会进口病理学小组 (GEPI-SEIMC)、西班牙家庭和社区医学学会 (SEMFYC)、西班牙初级保健医生学会 (SEMERGEN) 和西班牙急诊医学学会 (SEMES) 制定的《西班牙进口发热疾病诊断和管理指南》执行摘要。

IF 2.6 4区医学

Enfermedades infecciosas y microbiologia clinica Pub Date : 2024-08-01 DOI: 10.1016/j.eimc.2024.05.002

{"title":"Resumen ejecutivo de las Guías Española de Diagnóstico y Manejo de Enfermedades Febriles Importadas de la Sociedad Española de Medicina Tropical y Salud Internacional (SEMTSI), el Grupo de Patología Importada de la Sociedad Española de Enfermedades Infecciosas y microbiología clínica (GEPI-SEIMC), la Sociedad Española de Medicina de Familia y Comunitaria (SEMFYC), la Sociedad Española de Médicos de Atención Primaria (SEMERGEN) y la Sociedad Española de Medicina de Urgencias y Emergencias (SEMES)","authors":"","doi":"10.1016/j.eimc.2024.05.002","DOIUrl":"10.1016/j.eimc.2024.05.002","url":null,"abstract":"<div><p>The Spanish Society of Tropical Medicine and International Health (SEMTSI), the Spanish Society of Infectious Diseases and Clinical Microbiology (SEIMC), the Spanish Society of Emergency Medicine (SEMES), the Spanish Society of Primary Care Physicians (SEMERGEN) and the Spanish Society of Family and Community Medicine (SEMFYC) have elaborated a consensus statement on the diagnosis and management of patients with imported febrile illnesses.</p><p>Twenty authors with different backgrounds and representing different healthcare perspectives (ambulatory primary care, travel and tropical medicine specialists, emergency medicine, hospital care, microbiology and parasitology and public health), identified 39 relevant questions, which were organized in 7 thematic blocks. After a systematic review of the literature and a thoughtful discussion, the authors elaborated 125 recommendations, as well as several tables and figures to be used as a consulting tool. The present executive summary shows a selection of some of the most relevant questions and recommendations included in the guidelines.</p></div>","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":"42 7","pages":"Pages 380-385"},"PeriodicalIF":2.6,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0213005X24002489/pdfft?md5=fbe6e606c7bc1604d760adfc33bfd98f&pid=1-s2.0-S0213005X24002489-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141547251","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Drug burden index in people living with HIV over 50 years of age in a real clinical practice cohort 真实临床实践队列中 50 岁以上艾滋病毒感染者的药物负担指数

IF 2.6 4区医学

Enfermedades infecciosas y microbiologia clinica Pub Date : 2024-08-01 DOI: 10.1016/j.eimc.2023.04.010

{"title":"Drug burden index in people living with HIV over 50 years of age in a real clinical practice cohort","authors":"","doi":"10.1016/j.eimc.2023.04.010","DOIUrl":"10.1016/j.eimc.2023.04.010","url":null,"abstract":"<div><h3>Objectives</h3><p>To determine DBI and its relationship with polypharmacy<span> and pharmacotherapeutic complexity (PC) in a cohort of PLWH over 50 years of age at follow-up of pharmacotherapy in a tertiary hospital.</span></p></div><div><h3>Methods</h3><p>Observational and retrospective study that included PLWH in active antiretroviral treatment over 50 years of age who have been followed up in outpatient pharmacy services. Pharmacotherapeutic complexity was estimated through Medication Regimen Complexity Index (MRCI). Collected variables included comorbidities, current prescriptions and its classification according to anticholinergic and sedative activity and associated risk of falls.</p></div><div><h3>Results</h3><p>Studied population included 251 patients (85.7% men; median age: 58 years, interquartile range: 54–61). There was a high prevalence of high DBI scores (49.2%). High DBI was significantly correlated with a high PC, polypharmacy, psychiatric comorbidity and substances abuse (<em>p</em>  =85), antidepressant drugs (N06A) (<em>n</em>  <span>41) and antiepileptic drugs (N03A) (</span><em>n</em>  =18). Most frequent drugs associated with risk of falls were anxiolytics (N05B) (<em>n</em>  =61) and antidepressants (N06A) (<em>n</em>  <!-->41).</p></div><div><h3>Conclusion</h3><p>The DBI score in older PLWH is high and it is related to PC, polypharmacy, mental diseases and substance abuse as is the prevalence of fall-related drugs. Control of these parameters as well as the reduction of the sedative and anticholinergic load should be included in the lines of work in the pharmaceutical care of people living with HIV+.</p></div>","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":"42 7","pages":"Pages 347-353"},"PeriodicalIF":2.6,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134903980","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Tendencia en la vacunación en personas con infección por VIH participantes en la Encuesta Hospitalaria de pacientes con VIH, 2006-2021 2006-2021 年参与艾滋病医院住院病人调查的艾滋病毒感染者接种疫苗的趋势

IF 2.6 4区医学

Enfermedades infecciosas y microbiologia clinica Pub Date : 2024-08-01 DOI: 10.1016/j.eimc.2023.06.002

{"title":"Tendencia en la vacunación en personas con infección por VIH participantes en la Encuesta Hospitalaria de pacientes con VIH, 2006-2021","authors":"","doi":"10.1016/j.eimc.2023.06.002","DOIUrl":"10.1016/j.eimc.2023.06.002","url":null,"abstract":"<div><h3>Objective</h3><p>To assess the trend in hepatitis A, hepatitis B, pneumococcal, tetanus and seasonal influenza vaccination in people with HIV infection and to analyse associated factors.</p></div><div><h3>Methods</h3><p>The hospital survey of patients with HIV, an annual cross-sectional study conducted on a fixed day (2006-2021), was used. Inpatients and outpatients were included. Trends in vaccination and associated factors were analysed using logistic regression.</p></div><div><h3>Results</h3><p>A total of 8643 participants were included. Vaccination rates increased to 65.3% for hepatitis A, 83.7% for hepatitis B, 49.3% for tetanus, 68.9% for pneumococcal and 74.5% for seasonal influenza in 2021. Factors positively associated with vaccination were older age for pneumococcal and influenza vaccination; higher educational level for hepatitis A and tetanus; living in a closed institutions or prison for tetanus, pneumococcal and influenza; and having acquired HIV through sex between men for hepatitis A, hepatitis B and pneumococcal. In addition, being on antiretroviral treatment and having a high CD4 count were positively associated with vaccination for all these diseases. Factors inversely associated with vaccination were being older (hepatitis A, hepatitis B and tetanus), being an immigrant (tetanus and seasonal influenza) and being an injection drug user/ex-user for hepatitis A and hepatitis B.</p></div><div><h3>Conclusions</h3><p>Vaccination in people with HIV has increased in the study period. The results are in line with the recommendations in this population, although there is still room to reach the established vaccination indicators.</p></div>","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":"42 7","pages":"Pages 339-346"},"PeriodicalIF":2.6,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128446274","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Desenlace inesperado de amigdalitis pultácea en persona joven sin comorbilidad 无并发症的年轻人患扁桃体炎的意外结果

IF 2.6 4区医学

Enfermedades infecciosas y microbiologia clinica Pub Date : 2024-08-01 DOI: 10.1016/j.eimc.2023.12.006

引用次数: 0

Impacto de la inmunización con nirsevimab en las infecciones por VRS atendidas en urgencias pediátricas: primeros resultados en un hospital terciario de Madrid nirsevimab 免疫接种对儿科急诊室 RSV 感染的影响：马德里一家三级医院的初步结果。

IF 2.6 4区医学

Enfermedades infecciosas y microbiologia clinica Pub Date : 2024-08-01 DOI: 10.1016/j.eimc.2024.04.010

{"title":"Impacto de la inmunización con nirsevimab en las infecciones por VRS atendidas en urgencias pediátricas: primeros resultados en un hospital terciario de Madrid","authors":"","doi":"10.1016/j.eimc.2024.04.010","DOIUrl":"10.1016/j.eimc.2024.04.010","url":null,"abstract":"<div><h3>Introduction</h3><p>Human respiratory syncytial virus (RSV) is the most commonly identified virus associated with lower respiratory tract infections. The monoclonal antibody nirsevimab immunization campaign began in our country in October 2023.</p></div><div><h3>Methods</h3><p>This study was conducted in the Pediatric Emergency Department (PED) of a tertiary care center in Madrid, Spain. The aim was to compare PED visits of patients eligible for immunization with nirsevimab who attended between weeks 40 and 52 of 2022 and 2023 and who had a confirmed diagnosis of RSV infection.</p></div><div><h3>Results</h3><p>During the study period, 264 out of 765 patients with confirmed RSV infection who attended the PED were eligible for immunization with nirsevimab and were selected for our analysis. The PED attendance was 80.3% in 2022 and 19.7% in 2023. The number of RSV-positive cases increased from week 42 in both analyzed periods, with a peak of maximum incidence between weeks 46 and 48. In 2022, the morphology of the case curve in the group of children eligible for immunization was similar to the overall curve. However, in 2023, we did not observe a similar increase in cases among patients eligible for immunization.</p></div><div><h3>Conclusion</h3><p>Immunization with nirsevimab during the 2023 RSV epidemic season had a beneficial effect, reducing the number of PED consultations for RSV infection.</p></div>","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":"42 7","pages":"Pages 367-372"},"PeriodicalIF":2.6,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141407589","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Consideraciones sobre la aplicación del plan formativo de Microbiología y Parasitología clínica en los hospitales de España: una encuesta nacional 西班牙医院实施临床微生物学和寄生虫学培训计划的考虑因素：全国调查

IF 2.6 4区医学

Enfermedades infecciosas y microbiologia clinica Pub Date : 2024-08-01 DOI: 10.1016/j.eimc.2023.06.006

{"title":"Consideraciones sobre la aplicación del plan formativo de Microbiología y Parasitología clínica en los hospitales de España: una encuesta nacional","authors":"","doi":"10.1016/j.eimc.2023.06.006","DOIUrl":"10.1016/j.eimc.2023.06.006","url":null,"abstract":"<div><h3>Introduction</h3><p>The specialty of Microbiology and Parasitology is a four-year multidisciplinary training with a central role in the diagnosis and epidemiological surveillance of infectious diseases.</p><p>The aim of this study is to analyze the degree of implementation of the official program and the degree of satisfaction of residents with their training.</p></div><div><h3>Methods</h3><p>We conducted an online survey distributed in eight sections to which active residents of the Specialty of Clinical Microbiology and Parasitology had access.</p></div><div><h3>Results</h3><p>A total of 69 responses were received, with a predominance of residents from the regions of Madrid (43.5%) and of FIR admission route (55%).</p><p>The areas in which the residents feel best prepared correspond to systematic bacteriology, antimicrobials and clinical aspects of microbiology. The areas with the worst preparation, on the other hand, are mycology, parasitology and microbiological emergencies.</p><p>There are significant differences between the clinical rotation time for residents with MIR access pathway with respect to residents with other degrees.</p><p>Respondents perceive a high degree of responsibility and a medium agreement with the quality of teaching. Attendance at clinical sessions and external rotations is frequent.</p><p>Research activity is perceived as complicated, both at the level of doctoral studies and with respect to entering research lines and the publication of scientific results.</p></div><div><h3>Conclusion</h3><p>Some points of improvement of the training itinerary have been identified that need to be reinforced. Likewise, it would be interesting to seek a better balance between care, teaching and research activities.</p></div>","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":"42 7","pages":"Pages 361-366"},"PeriodicalIF":2.6,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121166813","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0