Enfermedades infecciosas y microbiologia clinica最新文献

{"title":"New COVID-19 vaccination recommendations in Spain: Optimizing for next seasons","authors":"Pilar Arrazola ,&nbsp;María Fernández Prada ,&nbsp;Ángel Gil ,&nbsp;José Gómez Rial ,&nbsp;Cristina Hernán ,&nbsp;Rosario Menéndez ,&nbsp;Antoni Trilla ,&nbsp;Raúl Ortiz de Lejarazu","doi":"10.1016/j.eimc.2024.08.012","DOIUrl":"10.1016/j.eimc.2024.08.012","url":null,"abstract":"<div><div>Despite high initial vaccination rates, Spain's current COVID-19 vaccination coverage in recommended groups does not meet WHO targets. For the upcoming season, challenges include revising vaccination age, updating risk groups, and unifying criteria with flu vaccine co-administration. European Commission's advance purchase agreements limit access to certain vaccines, and the need for vaccines effective against current variants adds administrative complexities. Spain's COVID-19 vaccination recommendations should adapt to these specific circumstances. Using vaccines effective against predominant variants with appropriate response duration is crucial to protect at-risk populations. Enhancing training and health education campaigns for health professionals and the general public, alongside utilizing tools to simplify vaccination recommendations, can promote higher vaccination rates in Spain. Addressing these challenges is essential to ensure adequate protection and improve vaccination coverage, ultimately achieving better public health outcomes in the face of evolving COVID-19 threats.</div></div>","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":"43 1","pages":"Pages 36-46"},"PeriodicalIF":2.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11752446/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143022827","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Accidental intravenous probiotic injection in an immunocompromised patient: Implications and consequences","authors":"Idoia Bilbao ,&nbsp;María Pascual ,&nbsp;José Ramón Yuste ,&nbsp;José Luis del Pozo","doi":"10.1016/j.eimc.2024.08.004","DOIUrl":"10.1016/j.eimc.2024.08.004","url":null,"abstract":"","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":"43 1","pages":"Pages 58-59"},"PeriodicalIF":2.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143104648","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Screening for Crimean-Congo Haemorrhagic Fever Virus antibodies in humans living in an endemic area of Spain","authors":"Helena Miriam Lorenzo Juanes ,&nbsp;Montserrat Alonso-Sardón ,&nbsp;Belen Vicente ,&nbsp;Beatriz Rodríguez Alonso ,&nbsp;Amparo López-Bernus ,&nbsp;Josue Pendones Ulerio ,&nbsp;Rufino Alamo Sanz ,&nbsp;Antonio Muro ,&nbsp;Juan Luis Muñoz Bellido ,&nbsp;Moncef Belhassen-García","doi":"10.1016/j.eimc.2024.09.006","DOIUrl":"10.1016/j.eimc.2024.09.006","url":null,"abstract":"<div><h3>Introduction</h3><div>Crimean-Congo haemorrhagic fever (CCHF) is an emerging tick-borne viral disease. It has been described in Spain in both ticks and humans. Until July 2024 most cases have been described in the central-western part of the Iberian Peninsula. This study aims to assess the seroprevalence of antibodies against CCHF virus (CCHFV) in humans in the area that has reported the highest number of cases in Spain.</div></div><div><h3>Methods</h3><div>The study was conducted to estimate the seroprevalence of antibodies against CCHFV antibodies among patients referred to a hospital located in the central-western area of Spain, an endemic area for CCHFV of Spain. Patients were recruited from April 1, 2023, to June 30, 2023. A commercial ELISA was used to detect serum antibodies against the CCHFV.</div></div><div><h3>Results</h3><div>We screened 658 samples from 370 (56.2%) men, with a mean (±SD) age of 58.6 years (±14.3). Of these, 4 were IgG positive, representing an IgG seropositivity of 0.6% (95% CI, 0.01–1.19). None of these four patients recalled having a clinical picture that strongly suggested CCHF.</div><div>Over the study period, in the population analysed in an area with circulation of CCHFV the seroprevalence of antibodies was 0.6%.</div></div><div><h3>Conclusion</h3><div>Our results suggest active circulation of the virus in humans in western Spain. Although the risk of developing CCHF is currently considered low, physicians should be alert to the imminent possibility of developing new cases of CCHF.</div></div>","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":"43 1","pages":"Pages 23-27"},"PeriodicalIF":2.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143104872","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"More threats: The increase in tick-borne diseases and their spectrum","authors":"José A. Oteo,&nbsp;Ana M. Palomar","doi":"10.1016/j.eimc.2024.10.001","DOIUrl":"10.1016/j.eimc.2024.10.001","url":null,"abstract":"","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":"43 1","pages":"Pages 1-2"},"PeriodicalIF":2.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143179321","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A simple MALDI–TOF-MS method for the identification of non-mycobacterial aerobic actinomycetes growing on blood agar subcultures from positive MGIT cultures","authors":"Maria Jose Muñoz Davila ,&nbsp;Maria Teresa Cabezas Fernandez ,&nbsp;Ana Belen Esteban García ,&nbsp;Miguel José Martinez Lirola","doi":"10.1016/j.eimc.2024.08.009","DOIUrl":"10.1016/j.eimc.2024.08.009","url":null,"abstract":"","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":"43 1","pages":"Pages 55-57"},"PeriodicalIF":2.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143181436","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bartonelosis sistémica con granulomas hepatoesplénicos","authors":"Sara Rodríguez-Vega ,&nbsp;Julio Noval Menéndez ,&nbsp;Elena Criado Hevia ,&nbsp;Diana Galiana Martín","doi":"10.1016/j.eimc.2024.07.005","DOIUrl":"10.1016/j.eimc.2024.07.005","url":null,"abstract":"","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":"43 1","pages":"Pages 52-53"},"PeriodicalIF":2.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143104875","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Are corticosteroids safe in adolescent and adult patients with infectious mononucleosis? A retrospective cohort study","authors":"Emilio-Manuel Páez-Guillán,&nbsp;Joaquín Campos-Franco,&nbsp;Rosario Alende,&nbsp;Arturo González-Quintela","doi":"10.1016/j.eimc.2023.10.004","DOIUrl":"10.1016/j.eimc.2023.10.004","url":null,"abstract":"<div><h3>Background and aim</h3><div>The use of systemic corticosteroids during Epstein-Barr virus (EBV)-induced infectious mononucleosis<span> is a controversial but widespread practice. We aimed to investigate the frequency of complications in adolescents and adults with infectious mononucleosis in relation to the use of corticosteroids.</span></div></div><div><h3>Methods</h3><div>We reviewed the clinical records of 396 patients admitted to the hospital with infectious mononucleosis (52.0% male; median age, 19 years; range, 15–87 years), with a focus on both short-term (infectious and non-infectious) and long-term (hematological malignancies) complications in relation to corticosteroid use.</div></div><div><h3>Results</h3><div>A total of 155 (38.6%) patients received corticosteroids at some point during infectious mononucleosis. Corticosteroid use was significantly (<em>P</em> <!-->≤<!--> <!-->0.002) associated with sore throat, lymphadenopathy, leukocytosis, and with antibiotics use (mainly indicated after suspicion of tonsillar bacterial superinfection). Overall, 139/155 (89.7%) patients who were treated with corticosteroids also received antibiotics either before or during hospitalization, compared with 168/241 (69.7%) patients who did not. The frequency of short-term severe complications, either infectious (peritonsillar–parapharyngeal abscess or bacteremia) or non-infectious (splenic rupture, severe thrombocytopenia, myopericarditis, or lymphocytic meningitis) were similar in patients receiving and not receiving corticosteroids. After a median of 15 years of follow-up, only one Hodgkin's lymphoma was diagnosed, in a patient who was not treated with corticosteroids during infectious mononucleosis.</div></div><div><h3>Conclusions</h3><div>The use of systemic corticosteroids during EBV-induced infectious mononucleosis is generally safe, at least with concomitant antibiotic therapy. However, this should not encourage the use of corticosteroids in this context, given that their efficacy has yet to be demonstrated.</div></div>","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":"43 1","pages":"Pages 10-16"},"PeriodicalIF":2.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138535698","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Indirect impact of PCV10 children vaccination on the serotype distribution and antimicrobial resistance of Streptococcus pneumoniae causing invasive disease in adults over 50 in Colombia, 2005–2019: Observational analysis","authors":"Carolina Duarte ,&nbsp;Clara Inés Agudelo ,&nbsp;Carlos Castañeda-Orjuela ,&nbsp;Jaime Moreno ,&nbsp;Olga Marina Sanabria ,&nbsp;Adriana Bautista ,&nbsp;Elizabeth Castañeda","doi":"10.1016/j.eimc.2023.07.002","DOIUrl":"10.1016/j.eimc.2023.07.002","url":null,"abstract":"<div><h3>Introduction</h3><div><span>The introduction of pneumococcal conjugate vaccine (PCV) into childhood vaccination programmes has reduced the prevalence of vaccine serotypes (VTs) that cause invasive pneumococcal disease (IPD) in children. In the elderly population, an impact has also been seen through indirect protection (herd effect). The aim of this study was to estimate the changes in serotype distribution and antimicrobial susceptibility of </span><span><span>Streptococcus pneumoniae</span></span> isolates recovered from adult IPD and to evaluate the indirect effect of immunization with PCV10 based on laboratory records by analyzing the period from 2005 to 2019 for six years before and eight years after the universal PCV10 administration to Colombian children.</div></div><div><h3>Methods</h3><div>A total of 2204 <span><em>S. pneumoniae</em></span> isolates from adults (≥50 years) with IPD were analyzed. The analysis examined the percentage changes in proportions (prevalence) and percentage variations in population rates (annual reported rates – ARR) of VTs between the pre-PCV10 (2005–2009) and post-PCV10 (2015–2019) periods.</div></div><div><h3>Results</h3><div>The findings were (1) evidence of a significant percentage decrease of pneumococcal VT10 causing IPD in adults (50% pre-PCV10 and 16% post-PCV10); (2) significant increase of serotype 19A (from 1.6% to 14.8%) and less important increase of serotype 3 (from 10.5% to 14.5%) and non-vaccine serotypes (NVT) (from 21.4% to 38.4%) non-significant; and (3) meningitis and non-meningitis multidrug resistant isolates associated with serotype 19A. An improvement in the surveillance system is associated with the immunization of children, as noted by the increased ARRs across the analysis period.</div></div><div><h3>Conclusions</h3><div>Our results show the indirect impact of PCV10 vaccination in children on the VT10 distribution and antimicrobial resistance of <em>S. pneumoniae</em> causing IPD in Colombian adults over 50 when comparing the pre-PCV10 (2005–2009) and post-PCV10 (2015–2019) periods.</div></div>","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":"43 1","pages":"Pages 3-9"},"PeriodicalIF":2.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133831374","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of automated nucleic acid extraction platforms on plasma Cytomegalovirus DNA loads quantitated by real-time PCR normalized to the 1st WHO international standard","authors":"Ángela Sánchez-Simarro ,&nbsp;Eliseo Albert ,&nbsp;Paula Michelena ,&nbsp;Estela Giménez ,&nbsp;David Navarro","doi":"10.1016/j.eimc.2024.07.008","DOIUrl":"10.1016/j.eimc.2024.07.008","url":null,"abstract":"<div><h3>Introduction</h3><div>The extent to which commercially available nucleic acid extraction platforms impact the magnitude of Cytomegalovirus (CMV) DNA loads measured in plasma specimens by 1st WHO standard-normalized real-time PCR assays is uncertain.</div></div><div><h3>Methods</h3><div>This retrospective study compares the performance of Abbott m2000sp, Qiagen QIAsymphony SP, and KingFisher Flex platforms using plasma samples from allogeneic hematopoietic stem cell transplant recipients and plasma spiked with the CMV AD169 strain. The Abbott RealTi<em>m</em>e CMV PCR assay was used for CMV DNA quantitation.</div></div><div><h3>Results</h3><div>Maximum differences in CMV DNA loads quantified in plasma from 11 allo-HSCT and spiked plasma over a wide range of viral DNA concentrations (2.0–4.0 log₁₀ IU/ml) were ≤0.5 log₁₀ IU/ml.</div></div><div><h3>Conclusions</h3><div>The CMV DNA extraction efficiency of the platforms evaluated varies. The impact of these variations on CMV DNA loads quantified in plasma may not be clinically relevant.</div></div>","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":"43 1","pages":"Pages 28-31"},"PeriodicalIF":2.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143104873","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Uñas gruesas en lactante","authors":"Karol Nicole Sabas Ortega,&nbsp;Lydia Corbalán Escortell,&nbsp;Mariano Ara Martín,&nbsp;Javier Sánchez Bernal","doi":"10.1016/j.eimc.2024.06.002","DOIUrl":"10.1016/j.eimc.2024.06.002","url":null,"abstract":"","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":"43 1","pages":"Pages 49-50"},"PeriodicalIF":2.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141697592","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}