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Endokrinologie最新文献

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Relationship between colloid droplets of thyroid follicular cells and serum thyroglobulin concentration in neonatal rats after thyrotropin releasing hormone (TRH) injection. 甲状腺激素释放激素(TRH)注射后新生大鼠甲状腺滤泡细胞胶体滴与血清甲状腺球蛋白浓度的关系
Endokrinologie Pub Date : 1982-07-01
K Yun, H Sugihara, M Izumi, H Hirayu, K Ohta, N Yonemitsu
{"title":"Relationship between colloid droplets of thyroid follicular cells and serum thyroglobulin concentration in neonatal rats after thyrotropin releasing hormone (TRH) injection.","authors":"K Yun,&nbsp;H Sugihara,&nbsp;M Izumi,&nbsp;H Hirayu,&nbsp;K Ohta,&nbsp;N Yonemitsu","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Thyrotropin Releasing Hormone (TRH) shows the obvious and long-durated stimulation to the neonatal thyroid tissue through the pituitary. The sequential changes of serum thyroglobulin (Tg) levels and light and ultrastructural change in the cells of the thyroid gland were studied after TRH injection into neonatal rats. TRH injection induced a rapid increase of the colloid droplets in the thyroid follicular cells followed by a slow increase in serum Tg levels. Ultrastructurally, although marked surface activities consisting of formation of pseudopods and colloid droplets were observed after TRH injection, luminal colloid did not appear to go across the intercellular space between the thyroid follicular cells.</p>","PeriodicalId":11605,"journal":{"name":"Endokrinologie","volume":"79 3","pages":"362-6"},"PeriodicalIF":0.0,"publicationDate":"1982-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17865228","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Oxytocin release from neurohypophysis evoked by preganglionic stimulation of the rat superior cervical ganglion. 节前刺激大鼠颈上神经节诱发神经垂体后叶催产素释放。
Endokrinologie Pub Date : 1982-07-01
S Lipinska, M Orłowska-Majdak, G Rubacha, W Z Traczyk
{"title":"Oxytocin release from neurohypophysis evoked by preganglionic stimulation of the rat superior cervical ganglion.","authors":"S Lipinska,&nbsp;M Orłowska-Majdak,&nbsp;G Rubacha,&nbsp;W Z Traczyk","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>1. In male rats under urethane/chloralose anaesthesia the pituitary gland was exposed by transpharyngeal approach. The following methods were applied: (a) posterior pituitary lobe incubation in situ with the anterior lobe removed and the posterior lobe elevated so that only the vessels between the lobe and the meninges are broken, and continuous exchange of the incubation fluid; (b) removal of the entire pituitary and continuous exchange of the fluid washing the cut proximal end of the pituitary stalk. 2. 20 to 30-min samples of incubation or washing fluid were collected for 3-5 hrs and oxytocin was assayed according to Van Dongen and Hays (1966). 3. Preganglionic stimulation of the superior cervical ganglion caused significant increase (ca. 25 times) of oxytocin release from the posterior pituitary lobe. 4. Preganglionic stimulation of the superior cervical ganglion did not alter oxytocin content in the fluid washing the cut proximal end of the pituitary stalk. 5. The sympathetic neurons of the superior cervical ganglia could evoked oxytocin release from the neurohypophysis but did not change its outflow from the hypothalamus to the neurohypophysis.</p>","PeriodicalId":11605,"journal":{"name":"Endokrinologie","volume":"79 3","pages":"385-92"},"PeriodicalIF":0.0,"publicationDate":"1982-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18143561","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Development of the Schwartz-Bartter syndrome after the administration of chlorpropamide and 1-deamino-8-D-arginine vasopressin. 氯丙胺和1-去氨基-8- d -精氨酸抗利尿激素后施瓦茨-巴特综合征的发展。
Endokrinologie Pub Date : 1982-07-01
Z Valkusz, F Laczi, F A László
{"title":"Development of the Schwartz-Bartter syndrome after the administration of chlorpropamide and 1-deamino-8-D-arginine vasopressin.","authors":"Z Valkusz,&nbsp;F Laczi,&nbsp;F A László","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":11605,"journal":{"name":"Endokrinologie","volume":"79 3","pages":"345-8"},"PeriodicalIF":0.0,"publicationDate":"1982-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18144537","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Thyrotropin, total thyroxine, thyroxine binding capacity and free thyroxine index in patients with gonadal dysgenesis (karyotype 45/XO). 促甲状腺素、总甲状腺素、甲状腺素结合能力和游离甲状腺素指数在性腺发育不良患者中的变化(核型45/XO)。
Endokrinologie Pub Date : 1982-07-01
S Kunkel, K Rudolf, H Rudolf
{"title":"Thyrotropin, total thyroxine, thyroxine binding capacity and free thyroxine index in patients with gonadal dysgenesis (karyotype 45/XO).","authors":"S Kunkel,&nbsp;K Rudolf,&nbsp;H Rudolf","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In 9 patients with gonadal dysgenesis (karyotype 45/XO), the responsiveness of thyreotropic cells of the pituitary was investigated by stimulation with thyreotropin-releasing hormone (TRH). Both after hormone substitution in the form of sequential therapy (mestranol/mestranol-chlormadinone acetate) and after the end of therapy the investigations were repeated. TSH was determined by RIA, total thyroxine and binding capacity of thyroxine binding globuline (TBC-index) by protein binding assay. The free thyroxine index (FT4-index) was calculated. The results show that the hypothalamic-pituitary unit in patients with gonadal dysgenesis reacts in a similar manner as in normal female subjects.</p>","PeriodicalId":11605,"journal":{"name":"Endokrinologie","volume":"79 3","pages":"367-72"},"PeriodicalIF":0.0,"publicationDate":"1982-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17246824","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Behavior of the hypothalamo-hypophyseal axis in a patient with asymmetric mixed gonadal dysgenesis (chromosome pattern 45,XO/46,XY) before and after gonad excision after with arginine, GRH and TRH stimulation]. [不对称混合性性腺发育不良(染色体型45,XO/46,XY)患者在精氨酸、GRH和TRH刺激下切除性腺前后下丘脑-垂体轴的行为]。
Endokrinologie Pub Date : 1982-07-01
K Rudolf, S Kunkel, H H Büttner, L Pelz, J Meissner
{"title":"[Behavior of the hypothalamo-hypophyseal axis in a patient with asymmetric mixed gonadal dysgenesis (chromosome pattern 45,XO/46,XY) before and after gonad excision after with arginine, GRH and TRH stimulation].","authors":"K Rudolf,&nbsp;S Kunkel,&nbsp;H H Büttner,&nbsp;L Pelz,&nbsp;J Meissner","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In a 12 years old patient with asymmetric mixed gonadal dysgenesis (karyotype 45, XO/46,XY) a stimulation test with arginine, gonadotropin-releasing hormone (GRH) and thyreotropin-releasing hormone (TRH) was performed before and after exstirpation of the gonads as well as after application of sex steroids. FSH, LH, PRL, HGH, TSH, testosterone and oestradiol were determined by radioimmunoassay. The results show an intact hypothalamo-pituitary axis which reacts with a normal negative feedback with respect to the secretion of gonadotropins after application of sex steroids.</p>","PeriodicalId":11605,"journal":{"name":"Endokrinologie","volume":"79 3","pages":"373-8"},"PeriodicalIF":0.0,"publicationDate":"1982-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17246825","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of glutaurine (gamma-l-glutamyl-taurine) on the serum glucocorticoid and estriol level in rats. 谷氨酰牛磺酸对大鼠血清糖皮质激素和雌三醇水平的影响。
Endokrinologie Pub Date : 1982-07-01
L Feuer, S U Nagy, G Csaba
{"title":"Effect of glutaurine (gamma-l-glutamyl-taurine) on the serum glucocorticoid and estriol level in rats.","authors":"L Feuer,&nbsp;S U Nagy,&nbsp;G Csaba","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":11605,"journal":{"name":"Endokrinologie","volume":"79 3","pages":"437-8"},"PeriodicalIF":0.0,"publicationDate":"1982-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18143566","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Results of endocrinolgic studies of the 3rd international crew of the scientific orbital station complex; Soyuz 29 - Salyut 6 - Soyuz 31 (joint space flight enterprise of the USSR - GDR). 2. Hormones and biologically active substances in blood]. [科学轨道站复合体第三届国际机组人员内分泌学研究结果;联盟29号-礼炮6号-联盟31号(苏联-民主德国的联合太空飞行企业)。2. [血液中的激素和生物活性物质]。
Endokrinologie Pub Date : 1982-07-01
R A Tigranjan, H Haase, N F Kalita, V M Ivanov, E A Pavlova, B V Afonin, L I Voronin, B Jarsumbeck
{"title":"[Results of endocrinolgic studies of the 3rd international crew of the scientific orbital station complex; Soyuz 29 - Salyut 6 - Soyuz 31 (joint space flight enterprise of the USSR - GDR). 2. Hormones and biologically active substances in blood].","authors":"R A Tigranjan,&nbsp;H Haase,&nbsp;N F Kalita,&nbsp;V M Ivanov,&nbsp;E A Pavlova,&nbsp;B V Afonin,&nbsp;L I Voronin,&nbsp;B Jarsumbeck","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Cortisol, insulin, somatotropin, thyreotropin, thyroxine, triiodothyronine, testosterone, aldosterone, c-AMP, c-GMP, prostaglandins (PGF1-x, PGF2-x, PGA + E), and renin concentrations in serum or plasma of the venous blood of the third international crew of the scientific orbital complex of \"Soyuz 29 - Salyut 6 - Soyuz 31\" were determined following the 7-day space flight. The increased activity of the renin-angiotensin-aldosterone system before the flight as well as variations in the pressor/depressor prostaglandin ratios indicate an increased strain during the pre-flight period. During the first stage of the post-flight period some parameters were changed due to the landing process and the returning to earth gravity. The associated physical load and the onset of reactions for enhancement of the orthostatic tolerance resulted in an increase of cyclic nucleotid and thyroxine concentrations. The relatively higher levels of the pressor PGs of group F in comparison with the prostaglandins A + E could be evaluated as a compensatory reaction for enhancement of the orthostatic tolerance. The cortisol and STH concentrations increased with growing motor activity. The variations seen after the 7-day space flight were essentially within the reference areas. It may be assumed that the readaptation was not yet totally accomplished by the 8th day after landing.</p>","PeriodicalId":11605,"journal":{"name":"Endokrinologie","volume":"80 1","pages":"37-41"},"PeriodicalIF":0.0,"publicationDate":"1982-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17809347","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Plasma oxytocin and estradiol in pelvic neurectomized rats with blocked parturition. 盆腔神经切除难产大鼠血浆催产素和雌二醇的变化。
Endokrinologie Pub Date : 1982-07-01
H W Burden, R C Gorewit, T M Louis, P D Muse, I E Lawrence
{"title":"Plasma oxytocin and estradiol in pelvic neurectomized rats with blocked parturition.","authors":"H W Burden,&nbsp;R C Gorewit,&nbsp;T M Louis,&nbsp;P D Muse,&nbsp;I E Lawrence","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>To determine if oxytocin and estradiol were effected by pelvic neurectomy (PN), utero-ovarian vein blood was collected from PN rats during the preparturient period and assayed for these hormones. Radioimmunoassayable oxytocin levels were not significantly different in any groups of sham operated (S) or PN animals on days 21 and 22 or PN animals on days 23 and 24. Estradiol (E2) levels rose significantly on day 22 in S animals but there was no significant change in E2 in PN rats throughout the time period studied, although E2 levels were generally high. These results indicate that the blocked parturition characteristic of PN animals cannot be attributed to altered oxytocin levels. The lack of a significant E2 surge on day 22 in PN rats may contribute to the failure of utero-ovarian vein prostaglandin F levels to rise in these animals during the preparturient period.</p>","PeriodicalId":11605,"journal":{"name":"Endokrinologie","volume":"79 3","pages":"379-84"},"PeriodicalIF":0.0,"publicationDate":"1982-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18143560","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Direct radioimmunoassay of progesterone in human plasma. 人血浆中黄体酮的直接放射免疫测定。
Endokrinologie Pub Date : 1982-07-01
R Stupnicki, E Kula
{"title":"Direct radioimmunoassay of progesterone in human plasma.","authors":"R Stupnicki,&nbsp;E Kula","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A direct method has been described which enables a specific assay of progesterone without extraction in human plasma or in other material containing corticosteroid binding globulin (CBG). When using 20 microliter of plasma per tube, a sensitivity of 6 pg/tube, or 0.3 ng/ml can be achieved. The precision and accuracy are comparable to those observed in methods involving extraction. The described method is particularly suitable for routine assays.</p>","PeriodicalId":11605,"journal":{"name":"Endokrinologie","volume":"80 1","pages":"1-7"},"PeriodicalIF":0.0,"publicationDate":"1982-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18186479","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of streptozotocin-induced diabetes on the activity of the sebaceous glands in rats. 链脲佐菌素诱导的糖尿病对大鼠皮脂腺活性的影响。
Endokrinologie Pub Date : 1982-07-01
Y C Toh
{"title":"Effect of streptozotocin-induced diabetes on the activity of the sebaceous glands in rats.","authors":"Y C Toh","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":11605,"journal":{"name":"Endokrinologie","volume":"80 1","pages":"56-9"},"PeriodicalIF":0.0,"publicationDate":"1982-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18186485","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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