Ejso最新文献

{"title":"Comment on “optimized machine learning model for predicting unplanned reoperation after rectal cancer anterior resection”","authors":"Fuji Lai, Sheng Li","doi":"10.1016/j.ejso.2024.109370","DOIUrl":"10.1016/j.ejso.2024.109370","url":null,"abstract":"","PeriodicalId":11522,"journal":{"name":"Ejso","volume":"51 1","pages":"Article 109370"},"PeriodicalIF":3.5,"publicationDate":"2024-11-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142643977","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Establishment a nomogram model for preoperative prediction of the risk of cholangiocarcinoma with microvascular invasion","authors":"Jingyun Guo ,&nbsp;Maobing Wang ,&nbsp;Shuyi Xue ,&nbsp;Qinlei Wang ,&nbsp;Meng Wang ,&nbsp;Zhaowei Sun ,&nbsp;Juan Feng ,&nbsp;Yujie Feng","doi":"10.1016/j.ejso.2024.109361","DOIUrl":"10.1016/j.ejso.2024.109361","url":null,"abstract":"<div><h3>Objectives</h3><div>The research aimed to create and verify a nomogram model that can predict the likelihood of cholangiocarcinoma with microvascular invasion (MVI).</div></div><div><h3>Methods</h3><div>The clinical data of 476 patients with surgically confirmed cholangiocarcinoma were collected retrospectively. This included 240 cases of intrahepatic cholangiocarcinoma (iCCA), 85 cases of perihilar cholangiocarcinoma (pCCA), and 151 cases of extrahepatic cholangiocarcinoma (eCCA). Using this data, we conducted forward multivariate regression analysis to identify the factors that influence the risk of preoperative MVI in patients with cholangiocarcinoma. And using these variables, we developed three nomogram models.</div></div><div><h3>Results</h3><div>The variables in the model for predicting MVI of iCCA were lymph node metastasis, distant metastases, carcinoembryonic antigen, and tumor size, all of which had a significance level of P &lt; 0.05. The internal and external validation consistency index (C-index) were 0.831 and 0.781, respectively. The variables in the model for predicting MVI of pCCA were lymph node metastasis, carcinoembryonic antigen, and tumor size, all of which had a significance level of P &lt; 0.05. The internal and external validation consistency index (C-index) were 0.791 and 0.747. And the variables in eCCA were lymph node metastasis, distant metastases, carcinoembryonic antigen, and tumor size, all of which had a significance level of P &lt; 0.05. The internal and external validation consistency index (C-index) were 0.834 and 0.830.</div></div><div><h3>Conclusions</h3><div>we have developed and validated a preoperative nomogram model for predicting MVI in patients with iCCA, pCCA, and eCCA.</div></div>","PeriodicalId":11522,"journal":{"name":"Ejso","volume":"51 1","pages":"Article 109361"},"PeriodicalIF":3.5,"publicationDate":"2024-11-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142638449","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The growing precision of diagnostic pathways in thyroid nodule evaluation","authors":"Jasper Bekker,&nbsp;Volkert B. Wreesmann","doi":"10.1016/j.ejso.2024.109374","DOIUrl":"10.1016/j.ejso.2024.109374","url":null,"abstract":"","PeriodicalId":11522,"journal":{"name":"Ejso","volume":"51 1","pages":"Article 109374"},"PeriodicalIF":3.5,"publicationDate":"2024-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142616973","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of surgical intervention on overall survival in malignant pleural mesothelioma: A population-based cohort study with propensity score matching","authors":"Ting Zhang ,&nbsp;Zhaotong Wang ,&nbsp;Yuanhang Zuo ,&nbsp;Shuoxin Yin ,&nbsp;Ning Wang","doi":"10.1016/j.ejso.2024.109372","DOIUrl":"10.1016/j.ejso.2024.109372","url":null,"abstract":"<div><h3>Background</h3><div>Malignant pleural mesothelioma (MPM) is a rare and aggressive cancer with limited treatment options. This study aims to assess the impact of surgical intervention on overall survival (OS) in patients with MPM and to identify prognostic factors influencing survival outcomes.</div></div><div><h3>Methods</h3><div>Data from the SEER-17 Database between 2000 and 2019 were analyzed. Patients were categorized into surgery and no-surgery groups. Survival analyses were conducted using Kaplan-Meier curves and Cox proportional hazards models. Propensity score matching (PSM) was applied to reduce biases.</div></div><div><h3>Results</h3><div>The study included a total of 3901 MPM patients, with 1190 in the surgery group and 2711 in the no-surgery group. The median OS for the entire cohort was 10 months. The surgery group had a median OS of 15 months compared to 8 months in the no-surgery group (<em>p</em> &lt; 0.001). The 1-year and 5-year OS rates for surgery patients were 56.9 % and 11.2 %, respectively, while for no-surgery patients, they were 34.9 % and 3.7 % (<em>p</em> &lt; 0.001). Multivariate analysis indicated that no-surgery was an independent risk factor for worse OS (HR 1.38, 95 % CI 1.21–1.39, <em>p</em> &lt; 0.001). After PSM, no-surgery remained an independent risk factor influencing OS. Subgroup analysis indicated that surgery benefited most groups except those aged ≥80 years, bilateral disease, N3 stage, and certain histological grades.</div></div><div><h3>Conclusion</h3><div>Surgical intervention significantly improves survival in patients with MPM. However, benefits vary across subgroups, and careful consideration of patient-specific factors is essential.</div></div>","PeriodicalId":11522,"journal":{"name":"Ejso","volume":"51 1","pages":"Article 109372"},"PeriodicalIF":3.5,"publicationDate":"2024-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142616949","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reproductive, obstetrical and oncological outcomes of fertility-sparing treatment for cervical cancer according to the FIGO 2018 staging system: A systematic review","authors":"Cristina Taliento ,&nbsp;Gennaro Scutiero ,&nbsp;Ginevra Battello ,&nbsp;Alessia Sala ,&nbsp;Giulia Pellecchia ,&nbsp;Rita Trozzi ,&nbsp;Martina Arcieri ,&nbsp;Matteo Pavone ,&nbsp;Nicolò Bizzarri ,&nbsp;Pantaleo Greco ,&nbsp;Lorenza Driul ,&nbsp;Frédéric Amant ,&nbsp;Anna Fagotti ,&nbsp;Giovanni Scambia ,&nbsp;Giuseppe Vizzielli ,&nbsp;Stefano Restaino","doi":"10.1016/j.ejso.2024.109359","DOIUrl":"10.1016/j.ejso.2024.109359","url":null,"abstract":"<div><h3>Objective</h3><div>We assessed reproductive, obstetrical, and oncological outcomes in patients who underwent fertility-sparing treatment by including studies that adhere to the FIGO 2018 staging system.</div></div><div><h3>Methods</h3><div>Data on recurrence, mortality, pregnancy rate, live birth rate, and preterm delivery rate were collected.</div></div><div><h3>Results</h3><div>In patients with stages IA1, IA2, and IB1, the recurrence rate was 4.7 % and the death rate was 0.6 %. For patients with stage IB2, the recurrence rate was 12.1 % and the death rate was 3.2 %. Pregnancy rates for conization/simple trachelectomy and radical trachelectomy were 61.7 % and 50 %, respectively. A higher live birth rate (84.4 % vs 58.6 %), and lower preterm birth rate (18.3 % vs 33.3 %) were observed in patients undergoing conization compared to radical trachelectomy.</div></div><div><h3>Conclusion</h3><div>We found a recurrence rate of 4.7 % in patients with stage less than or equal to IB1 and 12.1 % in those with stage IB2. A higher rate of preterm delivery was observed in patients who underwent radical trachelectomy.</div></div>","PeriodicalId":11522,"journal":{"name":"Ejso","volume":"51 1","pages":"Article 109359"},"PeriodicalIF":3.5,"publicationDate":"2024-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142616965","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Women in Surgical Oncology: What I, as a female surgeon, have contributed to the sarcoma community?","authors":"Sylvie Bonvalot","doi":"10.1016/j.ejso.2024.109363","DOIUrl":"https://doi.org/10.1016/j.ejso.2024.109363","url":null,"abstract":"","PeriodicalId":11522,"journal":{"name":"Ejso","volume":" ","pages":"109363"},"PeriodicalIF":3.5,"publicationDate":"2024-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142616918","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Curative-intent surgery for solitary bone metastasis from extremity and trunk wall sarcoma: What are the outcomes and complications?","authors":"Liuzhe Zhang ,&nbsp;Jean-Camille Mattei ,&nbsp;Anthony M. Griffin ,&nbsp;Kim Tsoi ,&nbsp;Peter C. Ferguson ,&nbsp;Jay S. Wunder","doi":"10.1016/j.ejso.2024.109369","DOIUrl":"10.1016/j.ejso.2024.109369","url":null,"abstract":"<div><h3>Introduction</h3><div>Approximately 40–50 % of sarcoma patients will develop lung metastasis, but only 10 % will develop bone metastasis. The survival benefit of surgery for solitary bone metastasis remains unclear.</div></div><div><h3>Methods</h3><div>From 1987 to 2019, 47 patients who underwent curative-intent treatment for localized bone or soft tissue sarcoma in the extremities or trunk wall developed solitary bone metastases as the first distant recurrence. Of them, 51 % (24/47) received curative-intent metastasectomy. We compared the clinicopathologic characteristics of the metastasectomy versus non-metastasectomy patients and evaluated the prognostic impact of solitary bone metastasectomy. The primary outcome measure was disease-specific survival (DSS) after developing solitary bone metastasis.</div></div><div><h3>Results</h3><div>The post-metastasis DSS was worse with larger primary tumour size (HR 1.09; 95 % CI 1.02–1.16; p = 0.01) and bone metastasis in the pelvis or spine versus other bones (HR 3.79, 95 % CI 1.46–9.87; p = 0.01), and better with curative-intent surgery for the solitary bone metastasis (HR 0.14; 95 % CI 0.06–0.34; p &lt; 0.001). The median DSS was 43 (95 % CI, 24–69) months for the metastasectomy group vs. 13 (95 % CI, 7–19) months for the non-metastasectomy group (p &lt; 0.001). The metastasectomy group had fewer patients with metastasis in the spine or pelvis and longer metastasis-free interval. In the multivariate analysis, curative-intent surgery for solitary bone metastasis was associated with better survival (HR 0.21; 95 % CI 0.08–0.53; p = 0.001).</div></div><div><h3>Conclusions</h3><div>Curative-intent surgery for solitary bone metastasis from sarcoma is associated with a better prognosis and is a reasonable treatment strategy whenever feasible.</div></div>","PeriodicalId":11522,"journal":{"name":"Ejso","volume":"51 1","pages":"Article 109369"},"PeriodicalIF":3.5,"publicationDate":"2024-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142638446","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prospective evaluation of MRI artefacts following breast conserving surgery and sentinel lymph node dissection with the magnetic technique","authors":"Allan Jazrawi ,&nbsp;Eirini Pantiora ,&nbsp;Shahin Abdsaleh ,&nbsp;Chin Lian Ng ,&nbsp;Athanasios Zouzos ,&nbsp;Tanja Gagliardi ,&nbsp;Fredrik Wärnberg ,&nbsp;Staffan Eriksson ,&nbsp;Andreas Karakatsanis","doi":"10.1016/j.ejso.2024.109368","DOIUrl":"10.1016/j.ejso.2024.109368","url":null,"abstract":"<div><h3>Introduction</h3><div>Superparamagnetic Iron Oxide (SPIO) nanoparticles serve as a promising tracer for sentinel lymph node (SLN) detection in breast cancer. Concerns exist regarding artefacts on postoperative Magnetic Resonance Imaging (MRI), especially following breast conservation (BCS).</div></div><div><h3>Materials and methods</h3><div>In this prospective observational study, 97 women with DCIS or invasive breast cancer underwent BCS and SLN detection with peritumoral SPIO injection administered up to four weeks before surgery. Postoperatively, patients were followed with MRI and mammograms, and imaging outcomes were evaluated by four, independent breast radiologists, blinded to clinical data, using a predefined, standardized questionnaire.</div></div><div><h3>Results</h3><div>In 97 patients included, there was inter-rater discordance in the prevalence of “any artefact” (range: 24.1–74.4 %; weighted average: 32.4 %) and “SPIO specific artefact” (range: 12.0–49.4 %; weighted average: 20.9 %). The median area of “any artefact” was 9.24 cm² (iqr 4.72, 15.50) and SPIO specific artefact 9.88 (iqr 5.32, 15.5). Likert scores indicated higher difficulty interpreting MRI if artefacts were present (OR: 2.295, 95 % CI 1.028, 5.123; p = 0.043), but this was reduced if intravenous contrast was administered (OR: 0.177, 95 % CI 0.091, 0.342; p &lt; 0.001). Multivariable analysis identified free-hand SPIO administration as a risk factor (OR 8.929, 95 % CI 2.849, 27.778; p &lt; 0.001). All six patients with local recurrence were successfully diagnosed on MRI by all raters.</div></div><div><h3>Conclusion</h3><div>This prospective cohort study suggests that a targeted peritumoral SPIO injection can result in the removal of SPIO during lumpectomy and address the concerns for artefacts on postoperative MRI follow-up, in the selected patients that MRI may be warranted.</div></div>","PeriodicalId":11522,"journal":{"name":"Ejso","volume":"51 1","pages":"Article 109368"},"PeriodicalIF":3.5,"publicationDate":"2024-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142616951","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development and validation of a cross-modality tensor fusion model using multi-modality MRI radiomics features and clinical radiological characteristics for the prediction of microvascular invasion in hepatocellular carcinoma","authors":"Ao Meng ,&nbsp;Yinping Zhuang ,&nbsp;Qian Huang ,&nbsp;Li Tang ,&nbsp;Jing Yang ,&nbsp;Ping Gong","doi":"10.1016/j.ejso.2024.109364","DOIUrl":"10.1016/j.ejso.2024.109364","url":null,"abstract":"<div><h3>Objectives</h3><div>To develop and validate a cross-modality tensor fusion (CMTF) model using multi-modality MRI radiomics features and clinical radiological characteristics for the prediction of microvascular invasion (MVI) in hepatocellular carcinoma (HCC).</div></div><div><h3>Materials and methods</h3><div>This study included 174 HCC patients (47 MVI-positive and 127 MVI-negative) confirmed by postoperative pathology. The synthetic minority over-sampling technique was used to augment MVI-positive samples. The amplified dataset of 254 samples (127 MVI-positive and 127 MVI-negative) was randomly divided into training and test cohorts in a 7:3 ratio. Radiomics features were respectively extracted from arterial phase, delayed phase, diffusion-weighted imaging, and fat-suppressed T2-weighted imaging. The least absolute shrinkage and selection operator was used for feature selection. Univariate and multivariate logistic regression analyses were employed to identify clinical and radiological independent predictors. The selected multi-modality MRI radiomics features, clinical and radiological characteristics were used to construct the CMTF model, single modality (SM) model, early fusion (EF) model.</div></div><div><h3>Results</h3><div>The CMTF model demonstrated superior performance in predicting MVI compared to the SM and EF models. When integrating four MRI modalities, the CMTF model achieved a high area under the curve (AUC) with 95 % confidence interval (95 % CI) of 0.894 (0.820–0.968). Additionally, incorporating clinical and radiological characteristics further enhanced the predictive performance of CMTF model, the AUC (95 % CI) value increased to 0.945 (0.892–0.998).</div></div><div><h3>Conclusion</h3><div>The CMTF model showed promising performance in preoperative MVI prediction, providing a more effective non-invasive detection tool for HCC patients.</div></div>","PeriodicalId":11522,"journal":{"name":"Ejso","volume":"51 1","pages":"Article 109364"},"PeriodicalIF":3.5,"publicationDate":"2024-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142616947","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Filler advert- Sciencedirect","authors":"","doi":"10.1016/S0748-7983(24)01418-5","DOIUrl":"10.1016/S0748-7983(24)01418-5","url":null,"abstract":"","PeriodicalId":11522,"journal":{"name":"Ejso","volume":"50 11","pages":"Article 109350"},"PeriodicalIF":3.5,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142572510","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}