EjsoPub Date : 2025-07-22DOI: 10.1016/S0748-7983(25)00764-4
{"title":"Advert ESSO Hands on Course on Thyroid Cancer Surgery","authors":"","doi":"10.1016/S0748-7983(25)00764-4","DOIUrl":"10.1016/S0748-7983(25)00764-4","url":null,"abstract":"","PeriodicalId":11522,"journal":{"name":"Ejso","volume":"51 8","pages":"Article 110336"},"PeriodicalIF":3.5,"publicationDate":"2025-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144680622","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
EjsoPub Date : 2025-07-15DOI: 10.1016/j.ejso.2025.110331
Dong Seung Shin , Jiwon Park , Hyunwoo Lee , Woong Ki Park , Se Kyung Lee , Byung Joo Chae , Jonghan Yu , Jeong Eon Lee , Seok Won Kim , Seok Jin Nam , Hee Jun Choi , Jai Min Ryu
{"title":"Potential for omitting sentinel lymph node biopsy in patients with human epidermal growth factor receptor 2-positive or triple negative breast cancer with non-breast pCR after neoadjuvant chemotherapy","authors":"Dong Seung Shin , Jiwon Park , Hyunwoo Lee , Woong Ki Park , Se Kyung Lee , Byung Joo Chae , Jonghan Yu , Jeong Eon Lee , Seok Won Kim , Seok Jin Nam , Hee Jun Choi , Jai Min Ryu","doi":"10.1016/j.ejso.2025.110331","DOIUrl":"10.1016/j.ejso.2025.110331","url":null,"abstract":"<div><h3>Background</h3><div>Pathologic complete response (pCR) after neoadjuvant chemotherapy (NACT) predicts favorable outcomes in HER2-positive and triple-negative breast cancer (TNBC). While breast and axillary pCR often coexist, some patients with residual breast disease still achieve axillary pCR. This study evaluated axillary pCR rates and factors in this subgroup, and the potential to omit sentinel lymph node biopsy (SLNB) in selected patients.</div></div><div><h3>Methods</h3><div>We retrospectively reviewed 1043 patients with HER2-positive or TNBC who did not achieve breast pCR after NACT and underwent surgery between 2008 and 2021 at a single institution. Clinicopathological features were compared between axillary pCR and non-pCR groups. Logistic regression analyses identified predictors of axillary pCR.</div></div><div><h3>Results</h3><div>Axillary pCR was observed in 648 (62.1 %) of 1043 patients who did not achieve breast pCR after NACT. The axillary pCR rate was 91.3 % in clinically node-negative (cN0) patients and 55.4 % in cN-positive patients. Axillary pCR rates decreased as the size of the residual breast tumor increased in both cN0 and cN-positive patients. Axillary pCR rates exceeded 94 % in patients with cN0 and residual tumor size of 1 cm or less. Multivariable analysis identified lower clinical N stage, smaller residual breast tumor size, and absence of lymphovascular invasion as independent predictors of axillary pCR.</div></div><div><h3>Conclusions</h3><div>A substantial proportion of HER2-positive or TNBC patients without breast pCR after NACT achieved axillary pCR, especially those with cN0 status and small residual tumors. These results support the potential omission of SLNB in selected patients and highlight the need for prospective validation and predictive model development.</div></div>","PeriodicalId":11522,"journal":{"name":"Ejso","volume":"51 10","pages":"Article 110331"},"PeriodicalIF":3.5,"publicationDate":"2025-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144662334","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
EjsoPub Date : 2025-07-14DOI: 10.1016/j.ejso.2025.110326
Juhana Rautiola , Johan Björklund , Renata Zelic , Francesco Pellegrino , Per Henrik Vincent , Peter Wiklund , Markus Aly , Henrik Falconer , Olof Akre
{"title":"Pelvic lymph-node dissections in bladder and prostate cancer surgery and the risk of postoperative venous thromboembolism","authors":"Juhana Rautiola , Johan Björklund , Renata Zelic , Francesco Pellegrino , Per Henrik Vincent , Peter Wiklund , Markus Aly , Henrik Falconer , Olof Akre","doi":"10.1016/j.ejso.2025.110326","DOIUrl":"10.1016/j.ejso.2025.110326","url":null,"abstract":"<div><h3>Introduction</h3><div>To evaluate the risk of venous thromboembolic events in patients operated with radical cystectomy or radical prostatectomy and pelvic lymph-node dissection.</div></div><div><h3>Material and methods</h3><div>Patients operated with radical cystectomy for bladder cancer or with radical prostatectomy for prostate cancer from 1997 through 2016 were identified from Swedish nationwide registers. We estimated odds ratios of association between lymph-node dissection and pulmonary embolism and deep venous thrombosis (DVT) using logistic regression adjusted for the probability of having lymph-node dissection.</div></div><div><h3>Results</h3><div>In total, 6069 patients operated with radical cystectomy and 36 911 patients with radical prostatectomy were included. The risk of pulmonary embolism and DVT after radical cystectomy with lymph-node dissection was 1,89 % and 2,29 %, and without lymph-node dissection 1,99 % and 2,35 %, respectively. After radical prostatectomy and lymph-node dissection the risk for pulmonary embolism and DVT were 0,97 % and 1,36 %, and without lymph-node dissection 0,42 % and 0,49 %, respectively. Pelvic lymph-node dissection during a radical cystectomy was not associated with pulmonary embolism (OR 0,99; 95 % CI 0,65–1,51) or DVT (OR 0,99; 95 % CI 0,68–1,48), whereas lymph-node dissection during radical prostatectomy was associated with higher odds of both pulmonary embolism (OR 2,29; 95 % CI 1,67–3,09) and DVT (OR 2,95; 95 % CI 2,27–3,85).</div></div><div><h3>Conclusion</h3><div>Pelvic lymph-node dissection did not increase the risk of venous thromboembolism after a cystectomy, whereas we found an increased relative risk of venous thromboembolic events associated with radical prostatectomy with lymph-node dissection.</div></div>","PeriodicalId":11522,"journal":{"name":"Ejso","volume":"51 10","pages":"Article 110326"},"PeriodicalIF":3.5,"publicationDate":"2025-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144662335","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
EjsoPub Date : 2025-07-14DOI: 10.1016/j.ejso.2025.110330
Carmela Caballero , Andreas Brandl , Nada Santrac , Mariela Vasileva-Slaveva , Eduard-Alexandru Bonci , Dana Sochorova , Pallvi Kaul , Nikolaos Vassos , Carine Lecoq , Laura Lorenzon , Karol Polom
{"title":"European Society of Surgical Oncology Young Surgeons (Young ESSO): A path for training excellence, inclusive leadership and research engagement","authors":"Carmela Caballero , Andreas Brandl , Nada Santrac , Mariela Vasileva-Slaveva , Eduard-Alexandru Bonci , Dana Sochorova , Pallvi Kaul , Nikolaos Vassos , Carine Lecoq , Laura Lorenzon , Karol Polom","doi":"10.1016/j.ejso.2025.110330","DOIUrl":"10.1016/j.ejso.2025.110330","url":null,"abstract":"<div><div>Young ESSO, previously called ESSO Young Surgeons Alumni Club (EYSAC), is a committee facilitating meaningful collaborations for cancer surgery training and research among ESSO's young members. It is composed of ESSO members ≤45 years old and led by a Steering Committee and National Representatives from >50 countries. Young ESSO has evolved into a well-structured, influential community within ESSO. It contributes to the ESSO Research Academy and to the Educational Training Committee. We describe its history, structure and contribution to the mission and vision of ESSO: to cure cancer together through multidisciplinary approach, precision surgery and harmonized high-quality training in cancer surgery. As a pathway for leadership and research engagement for early-career surgeons, it represents ESSO's commitment to education and career development. We aim convey the aspirations Young ESSO for inclusiveness, advocating for women as leaders in surgical oncology and addressing disparities in cancer surgery training within and beyond Europe.</div></div>","PeriodicalId":11522,"journal":{"name":"Ejso","volume":"51 10","pages":"Article 110330"},"PeriodicalIF":3.5,"publicationDate":"2025-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144679887","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
EjsoPub Date : 2025-07-13DOI: 10.1016/j.ejso.2025.110317
Mojtaba Ahmadinejad, Saman Sheikhi, Fatemeh Eghbal
{"title":"Reply to: Reply to: Optimal timing of surgery after neoadjuvant chemoradiotherapy in rectal cancer: A retrospective analysis.","authors":"Mojtaba Ahmadinejad, Saman Sheikhi, Fatemeh Eghbal","doi":"10.1016/j.ejso.2025.110317","DOIUrl":"https://doi.org/10.1016/j.ejso.2025.110317","url":null,"abstract":"","PeriodicalId":11522,"journal":{"name":"Ejso","volume":" ","pages":"110317"},"PeriodicalIF":3.5,"publicationDate":"2025-07-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144717740","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
EjsoPub Date : 2025-07-12DOI: 10.1016/j.ejso.2025.110327
Liangyou Gu , Lin Yao , Qingbo Huang , Yonghui Chen , Peng Wu , Cheng Peng , Huaikang Li , Peng Zhang , Yaoyao Zheng , Baojun Wang , Zhisong He , Xin Ma , Xu Zhang
{"title":"Robotic versus open level III-IV inferior vena cava thrombectomy: A multicenter, retrospective, propensity-matched analysis","authors":"Liangyou Gu , Lin Yao , Qingbo Huang , Yonghui Chen , Peng Wu , Cheng Peng , Huaikang Li , Peng Zhang , Yaoyao Zheng , Baojun Wang , Zhisong He , Xin Ma , Xu Zhang","doi":"10.1016/j.ejso.2025.110327","DOIUrl":"10.1016/j.ejso.2025.110327","url":null,"abstract":"<div><h3>Background</h3><div>The safety and efficacy of robotic inferior vena cava thrombectomy (IVCTE) for level III-IV thrombus with a comparison to open IVCTE is still unclear. This study aimed to compare robotic vs open IVCTE for renal tumors with level III-IV tumor thrombus.</div></div><div><h3>Materials and methods</h3><div>We performed a retrospective analysis of patients who underwent R-IVCTE or O-IVCTE in four academic tertiary centers between 2015 and 2023. Propensity score-matching analysis was performed. Perioperative data and prognosis were reviewed. Progression-free survival and overall survival were analyzed by Kaplan-Meier survival curve, and comparison between groups was performed by log-rank test.</div></div><div><h3>Results</h3><div>A total of 34 and 70 patients underwent R-IVCTE and O-IVCTE, respectively. After matching, baseline characteristics were comparable (30 vs 30 patients). Of the matched cohorts, robotic procedures were associated with longer operative time (508 vs 322 min; p < 0.001), lower rate of cardiopulmonary bypass (33.3 % vs 66.7 %; p = 0.010), longer ICU stay (5 vs 2 days, p = 0.001), shorter postoperative hospital stay (10 vs 13 days, p = 0.021). Patients undergoing R-IVCTE had a higher level of serum aminotransferase and aspartate aminotransferase than those undergoing O-IVCTE at 1–2 days after surgery, and the difference had disappeared at 1 week after surgery. No difference was observed between the two approaches regarding estimated blood loss, complications, pathological variables and oncological outcomes.</div></div><div><h3>Conclusions</h3><div>R-IVCTE can be feasible and safe in selected cases of renal tumors with level III-IV tumor thrombus, which may achieve similar perioperative and oncological outcomes compared to O-IVCTE.</div></div>","PeriodicalId":11522,"journal":{"name":"Ejso","volume":"51 10","pages":"Article 110327"},"PeriodicalIF":3.5,"publicationDate":"2025-07-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144633895","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
EjsoPub Date : 2025-07-12DOI: 10.1016/j.ejso.2025.110313
Wei Zhang, Qidong Ge
{"title":"Comment on “Pre-operative radiotherapy for breast cancer patients receiving mastectomy and immediate autologous tissue reconstruction”","authors":"Wei Zhang, Qidong Ge","doi":"10.1016/j.ejso.2025.110313","DOIUrl":"10.1016/j.ejso.2025.110313","url":null,"abstract":"","PeriodicalId":11522,"journal":{"name":"Ejso","volume":"51 10","pages":"Article 110313"},"PeriodicalIF":3.5,"publicationDate":"2025-07-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144632448","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}