Dysphagia最新文献_第4页

Swallowing Dysfunction and Histopathological Changes in a Rat Model of Duchenne Muscular Dystrophy. 杜氏肌营养不良大鼠模型的吞咽功能障碍和组织病理学改变。

IF 2.3 3区医学

Dysphagia Pub Date : 2026-08-04 DOI: 10.1007/s00455-026-10991-y

Masayuki Kitano, Hiroe Ohnishi, Keiichi Tamura, Keisuke Mizuno, Yasuyuki Hayashi, Hideaki Okuyama, Masayoshi Yoshimatsu, Masae Sato, Yoshitaka Kawai, Hidetoshi Sakurai, Keitaro Yamanouchi, Koichi Omori, Yo Kishimoto

{"title":"Swallowing Dysfunction and Histopathological Changes in a Rat Model of Duchenne Muscular Dystrophy.","authors":"Masayuki Kitano, Hiroe Ohnishi, Keiichi Tamura, Keisuke Mizuno, Yasuyuki Hayashi, Hideaki Okuyama, Masayoshi Yoshimatsu, Masae Sato, Yoshitaka Kawai, Hidetoshi Sakurai, Keitaro Yamanouchi, Koichi Omori, Yo Kishimoto","doi":"10.1007/s00455-026-10991-y","DOIUrl":"https://doi.org/10.1007/s00455-026-10991-y","url":null,"abstract":"Duchenne muscular dystrophy (DMD) is associated with progressive dysphagia. Although histopathological changes in the masseter and tongue muscles have been reported in DMD rats, little is known regarding swallowing-related muscles, especially those involved in the pharyngeal phase. Therefore, this study evaluated the swallowing function and pathology of swallowing-related muscles in a DMD rat model. Seven male DMD rats and five wild-type (WT) rats were used. Their body weight and food intake amount were monitored weekly. Electromyography (EMG) was performed on the geniohyoid muscle to assess the compound muscle action potential (CMAP) amplitude, swallow frequency, and swallowing duration. It was conducted at 90 weeks in WT rats and at the time point of 10% body weight loss in DMD rats. Histopathological examination of the geniohyoid, mylohyoid, digastric, and tongue muscles was performed using hematoxylin and eosin and Masson's trichrome staining. DMD rats exhibited significant reductions in body weight and food intake amount. In four out of five muscles examined, the muscle fiber area significantly decreased. However, all five muscles showed increased fibrosis and central nuclei. EMG revealed that DMD rats had significantly reduced CMAP amplitude, reduced swallow frequency, and prolonged hyoid elevation duration. DMD rats exhibited impaired swallowing function and pathological changes in swallowing-related muscles, similar to those observed in patients with DMD. DMD rats are useful for basic research on swallowing function in DMD and for developing therapeutic strategies targeting dysphagia.","PeriodicalId":11508,"journal":{"name":"Dysphagia","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2026-08-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148668518","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Impact of Nasogastric Tubes (NGTs) on Swallow Function in Adults with Post-stroke Dysphagia: A Systematic Review. 鼻胃管（NGTs）对脑卒中后吞咽困难患者吞咽功能的影响：系统综述。

IF 2.3 3区医学

Dysphagia Pub Date : 2026-08-01 Epub Date: 2026-03-24 DOI: 10.1007/s00455-026-10926-7

Layal Hanna, Zaneta Mok, Lital Weizman, Angela Burge, Cassie McDonald

{"title":"The Impact of Nasogastric Tubes (NGTs) on Swallow Function in Adults with Post-stroke Dysphagia: A Systematic Review.","authors":"Layal Hanna, Zaneta Mok, Lital Weizman, Angela Burge, Cassie McDonald","doi":"10.1007/s00455-026-10926-7","DOIUrl":"10.1007/s00455-026-10926-7","url":null,"abstract":"Nasogastric Tubes (NGTs) are a first-line treatment for delivering short-term nutrition to stroke survivors with dysphagia. However, the impact of NGTs on swallowing function itself is not yet well understood, despite the clinical importance of understanding this relationship to guide NGT treatment decisions. This review examined current evidence on the effects of NGTs on swallowing function in this population, focusing on five outcomes of interest: overall swallowing function, penetration/aspiration, oral and pharyngeal transit times and pharyngeal residue. A systematic search of terms related to stroke, dysphagia and NGTs across four major databases identified 1099 records. Eight full-text articles met inclusion criteria, of which seven were a pre-post design and one was a randomised control trial. Sample sizes of included studies ranged from 21 to 147 participants and median ages were between 66.0 ± 8.5 to 73.2 ± 12.4 years. Other participant characteristics, such as time with NGT in situ, time since stroke and NGT type, were inconsistently reported. Six studies used an instrumental swallowing evaluation to evaluate change between conditions, however, significant methodological heterogeneity between studies was evident in the inclusion criteria and assessment methods reported. Data synthesis suggested the following trends when an NGT is present: greater overall dysphagia severity, longer pharyngeal transit times, increased severity of penetration/aspiration, higher rates of pneumonia and increased volume of pharyngeal residue. However, most studies had a moderate-high risk of bias (n = 7), limiting the strength of conclusions. More methodologically robust research is needed to clarify the impact of NGTs on swallowing physiology and inform clinical management of dysphagia in stroke survivors requiring an NGT.","PeriodicalId":11508,"journal":{"name":"Dysphagia","volume":" ","pages":"745-758"},"PeriodicalIF":2.3,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13457347/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147510383","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Swallowing Safety in an Older Patient with Tongue and Pharyngeal Morphological Variations. 舌咽形态变异老年患者的吞咽安全性。

IF 2.3 3区医学

Dysphagia Pub Date : 2026-08-01 Epub Date: 2026-01-23 DOI: 10.1007/s00455-025-10921-4

Taku Suzuki, Hiroshi Hasegawa, Tetsuo Akimoto, Jin Magara, Takanori Tsujimura, Makoto Inoue

引用次数: 0

Association of Coexisting Low Tongue Pressure and Sarcopenia with Pharyngeal Residue in Older Adults with Presbyphagia. 老年食Presbyphagia患者同时存在舌压低、肌肉减少和咽部残留的关系。

IF 2.3 3区医学

Dysphagia Pub Date : 2026-08-01 Epub Date: 2026-02-09 DOI: 10.1007/s00455-026-10934-7

Hiroyasu Furuya, Takeshi Kikutani, Yuri Yokota, Maiko Ozeki, Fumiyo Tamura

{"title":"Association of Coexisting Low Tongue Pressure and Sarcopenia with Pharyngeal Residue in Older Adults with Presbyphagia.","authors":"Hiroyasu Furuya, Takeshi Kikutani, Yuri Yokota, Maiko Ozeki, Fumiyo Tamura","doi":"10.1007/s00455-026-10934-7","DOIUrl":"10.1007/s00455-026-10934-7","url":null,"abstract":"In age-related swallowing decline, low tongue pressure (LTP) represents a localized functional decline, and sarcopenia represents a systemic functional decline. However, their combined relationship with swallowing function is not fully understood. We examined whether the coexistence of LTP and sarcopenia is associated with pharyngeal residue, an indicator of swallowing efficiency, among older patients with dysphagia. A cross-sectional study was conducted in 102 outpatients aged 65 years or older with dysphagia and no clear underlying pathology. LTP and sarcopenia were assessed, and their coexistence was quantified using an original Tongue-Sarcopenia Composite Score (TSCS; 0-2 points). The primary outcome was pharyngeal residue (Bolus Residue Scale ≥ 2) after ingestion of semisolid food, as evaluated via videofluoroscopic swallowing studies. The association was analyzed using multiple logistic regression. LTP was observed in 69.6% of patients, sarcopenia in 49.0%, and their coexistence in 38.2%. The prevalence of pharyngeal residue increased stepwise across TSCS groups: 30.0% in the 0-point group, 60.5% in the 1-point group, and 82.1% in the 2-point group (p < 0.001). Multivariable analysis showed an association between TSCS and pharyngeal residue (adjusted odds ratio, 3.53; 95% confidence interval, 1.86 to 7.22). This association remained consistent across sensitivity analyses. In older patients with dysphagia who had no clear underlying pathology, the coexistence of LTP and sarcopenia was associated with pharyngeal residue. Combined assessment of both factors revealed stepwise differences in prevalence.","PeriodicalId":11508,"journal":{"name":"Dysphagia","volume":" ","pages":"818-826"},"PeriodicalIF":2.3,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146141105","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Assessment of Hyoid Bone Movement by Simultaneous Ultrasound and Videofluoroscopic Imaging. 超声和显像同时评价舌骨运动。

IF 2.3 3区医学

Dysphagia Pub Date : 2026-08-01 Epub Date: 2026-03-24 DOI: 10.1007/s00455-026-10929-4

Nicholas S Schoenleb, Brittany N Krekeler, Anna K Hopkins, Suzanne E Boyce, Rebecca J Howell, David W Rule, T Douglas Mast

{"title":"Assessment of Hyoid Bone Movement by Simultaneous Ultrasound and Videofluoroscopic Imaging.","authors":"Nicholas S Schoenleb, Brittany N Krekeler, Anna K Hopkins, Suzanne E Boyce, Rebecca J Howell, David W Rule, T Douglas Mast","doi":"10.1007/s00455-026-10929-4","DOIUrl":"10.1007/s00455-026-10929-4","url":null,"abstract":"Ultrasound imaging shows promise for bedside tracking of oropharyngeal swallowing structures, but has not been validated against videofluoroscopy. The hyoid bone is readily visible on both ultrasound and fluoroscopy and has multiple muscular attachments involved in execution of swallowing movements. This study aims to validate ultrasound measurements of hyoid motion by quantitatively comparing simultaneously recorded ultrasound and videofluoroscopy data. Participants (N = 23) were recruited from standard-of-care videofluoroscopy studies during which an ultrasound array was positioned submentally to acquire simultaneous B-mode ultrasound imaging. Kinematic analyses of hyoid motion in both ultrasound and videofluoroscopic image data from 56 swallows were analyzed to validate the accuracy of ultrasound measurements. Methods for correction of transducer movement included static angle correction, based on the initial transducer angle, and dynamic translation/rotation, based on the time-dependent transducer position. Hyoid motion variables were compared using intra-class correlation coefficients, root-mean-square error, t tests, and F tests, and included time-dependent trajectories, maximum excursion, and peak velocity. Ultrasound measurements were corrected using dynamic translation/rotation closely agreed with videofluoroscopy (ICC = 0.892 for hyoid trajectories; mean ICC = 0.715 for summary statistics). A substantial portion of hyoid position measurement error was due to transducer motion (estimated as 0.37 cm). These results indicate that ultrasound imaging, when incorporating appropriate correction for transducer motion, can accurately track motion of the hyoid bone and serve as a useful technique for measuring swallowing movements.","PeriodicalId":11508,"journal":{"name":"Dysphagia","volume":" ","pages":"772-787"},"PeriodicalIF":2.3,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13130841/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147510426","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Prevalence of Infection and Sepsis Associated Dysphagia in Hospitalised Patients: A Retrospective Cross-sectional Study. 住院患者感染和败血症相关吞咽困难的患病率：一项回顾性横断面研究

IF 2.3 3区医学

Dysphagia Pub Date : 2026-08-01 Epub Date: 2026-03-04 DOI: 10.1007/s00455-026-10931-w

Ayodele Sasegbon, Karim Bastawisy, Ivy Cheng, Shaheen Hamdy

{"title":"The Prevalence of Infection and Sepsis Associated Dysphagia in Hospitalised Patients: A Retrospective Cross-sectional Study.","authors":"Ayodele Sasegbon, Karim Bastawisy, Ivy Cheng, Shaheen Hamdy","doi":"10.1007/s00455-026-10931-w","DOIUrl":"10.1007/s00455-026-10931-w","url":null,"abstract":"Little is known about the relationships between infections, sepsis and dysphagia. In this study, we aimed to assess the prevalence and factors associated with dysphagia in patients admitted to hospital with infections or sepsis. Participants ≥ 18 years admitted to hospital with infections or sepsis caused by pneumonia, urine tract infections or cholecystitis were recruited from an NHS Trust in the UK. Electronic patient record and clinical coding staff screened patient data from 01/02/2022 to 01/02/2023. Patients with previous dysphagia, acute head injuries or stroke were excluded. Those that remained had data extracted from their notes, including age, gender, length of stay (LOS), co-morbidities, and mortality. Data was then analysed using statistical tests, including Logistic regression. Over the study period, 4475 patients (M:2031, F:2444) were admitted with infections (Pneumonia 2465, UTI 1888 and Cholecystitis 401). Of these, 189 (4.2%) developed dysphagia during their inpatient stay (Pneumonia 6.0%, UTI 3.5%, Cholecystitis 0.8%). Additionally, 865 patients (M:434, F:431) were admitted with sepsis (Pneumonia 535, UTI 413 and Cholecystitis 55). Of these, 54 (6.2%) developed dysphagia (Pneumonia 9.3%, UTI 3.4%, Cholecystitis 3.6%). Logistic regression revealed that increasing age, the presence of sepsis, delirium, dementia and Parkinson's disease (PD) were significantly associated with an increased risk of dysphagia (OR = 1.02, 1.74, 1.60, 2.43, 3.88; P = 0.002, 0.013, 0.008, < 0.001, < 0.001). Our study has identified that dysphagia is associated with infections and sepsis. Additionally, patients with PD, delirium or dementia who are not known to have swallowing impairments are at risk of developing dysphagia should they be admitted with infections or sepsis.","PeriodicalId":11508,"journal":{"name":"Dysphagia","volume":" ","pages":"799-810"},"PeriodicalIF":2.3,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13457454/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147354207","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Accuracy of Otolaryngology-performed Simplified Flexible Endoscopic Evaluation of Swallowing (S-FEES): A Retrospective Analysis. 耳鼻喉科进行的简化柔性内镜吞咽评估（S-FEES）的准确性：回顾性分析。

IF 2.3 3区医学

Dysphagia Pub Date : 2026-08-01 Epub Date: 2026-02-17 DOI: 10.1007/s00455-026-10935-6

Sara Abu-Ghanem, Nancy Deng, James Alrassi, Lindsay Blank, James Cochran

{"title":"Accuracy of Otolaryngology-performed Simplified Flexible Endoscopic Evaluation of Swallowing (S-FEES): A Retrospective Analysis.","authors":"Sara Abu-Ghanem, Nancy Deng, James Alrassi, Lindsay Blank, James Cochran","doi":"10.1007/s00455-026-10935-6","DOIUrl":"10.1007/s00455-026-10935-6","url":null,"abstract":"Flexible endoscopic evaluation of swallowing (FEES) and modified barium swallow study (MBSS) are considered the gold standard studies for evaluating oropharyngeal swallow. In the United States, these studies are most commonly performed by speech-language pathologists (SLPs), although internationally FEES may be performed by otolaryngologists or other providers Limited literature exists on Otolaryngologist-performed FEES without the presence of SLP in the outpatient setting. This study presents the concept of Otolaryngology simplified screen FEES (S-FEES) and its accuracy compared to SLP-performed MBSS. A retrospective chart review of adult dysphagic patients presenting to an Otolaryngology clinic was performed, identifying patients who underwent Otolaryngology-performed S-FEES and SLP-performed MBSS within 3 months of each other. Demographic information and study findings were compiled and analyzed. Reliability and predictive values were calculated for S-FEES using SLP-performed MBSS as the standard. Overall, 89 patients, 52.8% male, with a mean age of 66.7 years, met the inclusion criteria. Within the group, 57.3% of patients were identified with normal S-FEES, 51.7% with normal laryngoscopy, and 68.5% with normal MBSS. Cohen's kappa for S-FEES and MBSS was 0.762. Otolaryngology performed S-FEES had 100% sensitivity and 85.9% specificity of detecting abnormal swallow when compared to SLP-performed MBSS. Positive and negative predictive values were 73.7% and 100%, respectively. Otolaryngology-performed S-FEES represents a streamlined application of the standard FEES protocol that can be readily incorporated into otolaryngology outpatient practice in the absence of an SLP. This simplified screen protocol demonstrated high sensitivity and negative predictive value for identifying patients who may benefit from referral for comprehensive swallowing evaluation by SLP.","PeriodicalId":11508,"journal":{"name":"Dysphagia","volume":" ","pages":"827-833"},"PeriodicalIF":2.3,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146212546","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Impact of Swallowing Training on Patients with Post-extubation Dysphagia after Endotracheal Intubation in the ICU: A Quasi-Experimental Study. 吞咽训练对ICU气管插管后拔管后吞咽困难患者的影响：一项准实验研究。

IF 2.3 3区医学

Dysphagia Pub Date : 2026-08-01 Epub Date: 2026-02-21 DOI: 10.1007/s00455-026-10924-9

Jieqiong Li, Ting Liu, Mi Zhang, Yipin Tang, Juan Han, Jiajia Ma, Xiaomei Li

{"title":"The Impact of Swallowing Training on Patients with Post-extubation Dysphagia after Endotracheal Intubation in the ICU: A Quasi-Experimental Study.","authors":"Jieqiong Li, Ting Liu, Mi Zhang, Yipin Tang, Juan Han, Jiajia Ma, Xiaomei Li","doi":"10.1007/s00455-026-10924-9","DOIUrl":"10.1007/s00455-026-10924-9","url":null,"abstract":"Post-extubation dysphagia (PED) in ICU patients can delay oral intake, prolong mechanical ventilation, and extend ICU stays. Despite its impact, evidence-based standard procedures for swallowing rehabilitation are lacking. This study aimed to investigate the benefits of a swallowing training program in patients with PED in the ICU. This quasi-experimental study was conducted from January to September 2024 and ICU units were randomly assigned to either a control group or an intervention group. The former were given routine rehabilitation care, whereas the latter received a swallowing training program to investigate best-evidence clinical practice, targeted enhancements were implemented for critical components with suboptimal adherence in swallowing screening and management protocols. Applying the swallowing training program to the intervention group, which included screening for dysphagia, indirect training (basic training), direct training (ingestion training), and the management of complications, for 14 days of intervention. Compared with those of the control group, the swallowing function (MD, 95% CI [2.13(0.27,3.98)], P = 0.025), functional oral intake (MD, 95% CI [1.05(0.29,1.81), P = 0.008), nasogastric tube removal (Log-rank P = 0.013; Cox HR = 0.51, 95% CI: 0.28-0.93, P = 0.028), and incidence of aspiration (P = 0.014) of patients in the intervention group significantly improved, while nutritional indicators did not significantly improve (P > 0.05). The results of this study demonstrated the effectiveness of using a swallowing training program for improving swallowing function, reducing the days of gastric tube retention and complication rates in ICU patients with PED. The results of this study provided evidence to promote early rehabilitation in critically ill patients.","PeriodicalId":11508,"journal":{"name":"Dysphagia","volume":" ","pages":"723-734"},"PeriodicalIF":2.3,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146257781","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Association between Oropharyngeal Dysphagia and Subgroups of Patients with Idiopathic Inflammatory Myopathy: A Cross-Sectional Study. 口咽吞咽困难与特发性炎性肌病亚组之间的关系：一项横断面研究。

IF 2.3 3区医学

Dysphagia Pub Date : 2026-08-01 Epub Date: 2026-02-21 DOI: 10.1007/s00455-026-10932-9

Monica Segura-Hernandez, Luis Fernando Galindo-Borbón, Miguel Ángel Pérez-Rodriguez

引用次数: 0

Ankyloglossia in Infants. 婴儿强直性咬合症。

IF 2.3 3区医学

Dysphagia Pub Date : 2026-08-01 Epub Date: 2026-03-09 DOI: 10.1007/s00455-026-10933-8

Azliana Aziz

引用次数: 0