Early human development最新文献

{"title":"Exploring the association between haematological markers of iron and general movements in 4-month-old infants exposed to anaemia in-utero","authors":"Kiran P. Nadgauda ,&nbsp;Deepa C. Metgud ,&nbsp;Roopa M. Bellad ,&nbsp;Deepthy M. Sadanandan ,&nbsp;Arend F. Bos ,&nbsp;Michael K. Georgieff","doi":"10.1016/j.earlhumdev.2024.106080","DOIUrl":"10.1016/j.earlhumdev.2024.106080","url":null,"abstract":"<div><h3>Background</h3><p>Iron is a vital micronutrient for brain development, influencing myelination, neurotransmitter balance, and the maturation of specific brain cells. Hence iron insufficiency in the foetal, neonatal and infancy period has the potential to influence the neuromotor development.</p></div><div><h3>Aims</h3><p>We aimed to describe haematological markers of iron at 4 months of age in infants exposed to prenatal anaemia and explore the association with their quality of general movements.</p></div><div><h3>Study design</h3><p>Cross sectional study nested within the RAPIDIRON-KIDS trial.</p></div><div><h3>Subjects</h3><p>All infants whose mothers were part of RAPIDIRON-KIDS trial, were eligible to participate in this study when the infants were 4 months old. Children suffering from fever or acute illness on the day of assessment, or with a history of either surgery, or admission to hospital in the first month were excluded.</p></div><div><h3>Outcome measures</h3><p>Haematological markers of iron (Haemoglobin and Ferritin level) and quality of general movements in infants at 4 months of age.</p></div><div><h3>Results</h3><p>120 infants were assessed with mean birth weight of 2685.5 g (±384.5) and median gestational age of 39 weeks [Q₁, Q₃:38,40]. There was no significant association between haemoglobin or ferritin levels with fidgety movements (<em>p</em> = 0.18 and <em>p</em> = 0.27, respectively). The combined effect of haemoglobin and ferritin estimates also did not show any significant association with the study groups (<em>p</em> = 0.21).</p></div><div><h3>Conclusion</h3><p>A majority of infants still had low iron indices at 4 months of age and this was not associated with the quality of general movements. A prospective longitudinal study needs to be considered in infants exposed to prenatal anaemia rather than assessing the outcomes at a single time point.</p></div>","PeriodicalId":11435,"journal":{"name":"Early human development","volume":"195 ","pages":"Article 106080"},"PeriodicalIF":2.2,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141757792","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Value of near-infrared spectroscopy in evaluating the risk of neonatal necrotizing enterocolitis: A systematic review and meta-analysis","authors":"Yan Gan ,&nbsp;Junjie Ying ,&nbsp;Xia Qiu ,&nbsp;Siyi You ,&nbsp;Ting Zhang ,&nbsp;Tiechao Ruan ,&nbsp;Ruixi Zhou ,&nbsp;Yanxiu Ye ,&nbsp;Yan Yue ,&nbsp;Li Zhang ,&nbsp;Dezhi Mu","doi":"10.1016/j.earlhumdev.2024.106083","DOIUrl":"10.1016/j.earlhumdev.2024.106083","url":null,"abstract":"<div><h3>Purpose</h3><p>Recently, near-infrared spectroscopy (NIRS) has been proposed for diagnosing patients with neonatal necrotizing enterocolitis (NEC). However, a consensus on the credibility of NIRS in evaluating NEC risk has not been reached. This meta-analysis aimed to evaluate the relationship between NEC and splanchnic regional tissue oxygen saturation (SrSO₂) and cerebral regional tissue oxygen saturation (CrSO₂) detected by NIRS to clarify the clinical value of NIRS in evaluating the risk of NEC.</p></div><div><h3>Methods</h3><p>Studies using NIRS to monitor regional tissue oxygen saturation (rSO₂) in neonates with NEC published in PubMed, Web of Science, Embase, and the Cochrane Library were searched from their inception to 30 July 2023. Mean difference (MD), pooled sensitivity, and pooled specificity, along with their 95 % confidence intervals (CI), were calculated, and the random-effects model was used for analysis. This study was registered with PROSPERO (no. CRD42022326783).</p></div><div><h3>Results</h3><p>Fourteen studies including 938 neonates (172 NEC, 766 controls) were identified. SrSO₂ was significantly decreased in patients with NEC (MD: -12.52, 95 % CI: −15.95, −9.08; <em>P</em> &lt; 0.00001), and this decrease was observed even before the diagnosis of NEC (MD: -13.79, 95 % CI: −17.97, −9.62; <em>P</em> &lt; 0.00001). The pooled sensitivity and specificity of SrSO₂ were 0.80 (95 % CI: 0.69, 0.88) and 0.90 (95 % CI: 0.61, 0.98), respectively. However, no significant difference in CrSO₂ was found (MD: -4.37, 95 % CI: −10.62, 1.88; <em>P</em> = 0.17).</p></div><div><h3>Conclusions</h3><p>SrSO₂, detected by NIRS, could be a valuable non-invasive method for differentiating NEC from non-NEC neonates. It could differentiate prior to NEC diagnosis.</p></div>","PeriodicalId":11435,"journal":{"name":"Early human development","volume":"195 ","pages":"Article 106083"},"PeriodicalIF":2.2,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S037837822400152X/pdfft?md5=8690a1794bbe60069ddf0de2ea343c8e&pid=1-s2.0-S037837822400152X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141765778","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Detecting month and year of birth effects on reproduction and marriage patterns in two long-term data sets","authors":"Martin Fieder,&nbsp;Susanne Huber","doi":"10.1016/j.earlhumdev.2024.106073","DOIUrl":"10.1016/j.earlhumdev.2024.106073","url":null,"abstract":"<div><p>This study examines the effects of birth month on reproduction and mating behavior using historical and contemporary census data from 1820 to 1970. The research examines the effect of birth month on the number of children for women and their male spouses, finding a monthly cycle for both men and women. In addition, the study examines whether birth month influences whether a person has ever been married. In support of previous research, we find clear birth month effects on the number of children for both women and their spouses, while the time series of ever being married shows a 60-month and a 10-year cycle, the latter possibly related to the solar cycle. Although the effects are small, both results, based on a large and representative dataset, indicate the importance of early life factors on mating and reproduction.</p></div>","PeriodicalId":11435,"journal":{"name":"Early human development","volume":"195 ","pages":"Article 106073"},"PeriodicalIF":2.2,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141698080","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Placenta histology related to flow and oxygenation in fetal congenital heart disease","authors":"Maartje C. Snoep ,&nbsp;Maaike Nijman ,&nbsp;Marco C. DeRuiter ,&nbsp;Mireille N. Bekker ,&nbsp;Moska Aliasi ,&nbsp;Johannes M.P.J. Breur ,&nbsp;Arend D.J. ten Harkel ,&nbsp;Manon J.N.L. Benders ,&nbsp;Lotte E. van der Meeren ,&nbsp;Monique C. Haak","doi":"10.1016/j.earlhumdev.2024.106079","DOIUrl":"10.1016/j.earlhumdev.2024.106079","url":null,"abstract":"<div><h3>Background</h3><p>Fetuses with congenital heart defects (CHD) show delayed neurodevelopment, fetal growth restriction (FGR) and placenta related complications. The neurodevelopmental delay may be, partly, attributed to placental factors.</p></div><div><h3>Aim</h3><p>As both placental development and fetal aortic flow/oxygenation influence neurodevelopment, placentas were compared within fetal CHD groups based on aortic oxygenation and flow, aiming to unravel the true effects in the developmental processes.</p></div><div><h3>Study design</h3><p>Placental tissues of pregnancies with fetal CHD and healthy controls were selected from biobanks of two Dutch academic hospitals (LUMC, UMCU). Additionally, biometry and Dopplers were assessed.</p></div><div><h3>Subjects</h3><p>CHD cases with reduced oxygenation (RO) towards the fetal brain were compared to cases with reduced flow (RF) in the aortic arch and healthy controls. Genetic abnormalities, termination of pregnancy, fetal demise and/or multiple pregnancies were excluded.</p></div><div><h3>Outcome measures</h3><p>Histological outcomes were related to fetal Dopplers and biometry. A placenta severity score was used to assess the severity of placental abnormalities per case.</p></div><div><h3>Results</h3><p>In CHD, significantly more delayed maturation, maternal vascular malperfusion, fetal hypoxia and higher placenta severity scores (median 14 in RO, 14 in RF, 5 in controls, <em>p</em> &lt; 0.001) were observed. Doppler abnormalities (PI UA &gt; p90, PI MCA &lt; p10, CPR &lt; p10) and FGR were more often found in CHD. There were no differences in placental abnormalities, fetal growth and fetal Dopplers between cases with RO and RF.</p></div><div><h3>Conclusion</h3><p>Fetal hemodynamics in the ascending aorta could not be related to placenta characteristics. We hypothesize that placental development influences neurodevelopment in excess of hemodynamics in CHD cases.</p></div>","PeriodicalId":11435,"journal":{"name":"Early human development","volume":"195 ","pages":"Article 106079"},"PeriodicalIF":2.2,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141757793","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Corrigendum to “Relationship of passive hypothermia during transport with the incidence of early multiorgan compromise in newborns with perinatal asphyxia” [Early Human Development 187 (2023) 105902]","authors":"","doi":"10.1016/j.earlhumdev.2024.106070","DOIUrl":"10.1016/j.earlhumdev.2024.106070","url":null,"abstract":"","PeriodicalId":11435,"journal":{"name":"Early human development","volume":"195 ","pages":"Article 106070"},"PeriodicalIF":2.2,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0378378224001397/pdfft?md5=8f5324d4322838741d37880426b782b3&pid=1-s2.0-S0378378224001397-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141466934","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prolonged COVID-19 related effects on early language development: A longitudinal study","authors":"Jovana Pejovic,&nbsp;Cátia Severino,&nbsp;Marina Vigário,&nbsp;Sónia Frota","doi":"10.1016/j.earlhumdev.2024.106081","DOIUrl":"10.1016/j.earlhumdev.2024.106081","url":null,"abstract":"<div><h3>Background</h3><p>There is growing evidence that COVID-19 brought changes that immediately affected early language development. Little is known for how long these COVID-19 related changes shaped development. The current study systematically and longitudinally addressed this issue, following up children's language development throughout the first 2.5 years.</p></div><div><h3>Method</h3><p>The present study follows up on the sample from Frota et al. (2022), which demonstrated that 7–9-month-old infants born and raised during the pandemic do not segment words unlike pre-pandemic peers. Four studies were conducted: (1) word segmentation task at 12 months of age (N_pandemic = 15); (2) word learning task at 20 months of age (N_pandemic = 20); (3) language and communication development up to 30 months of age, via CDI and CSBS parental reports (N_pandemic ranged 25–74); (4) overall development at 30 months of age using the Griffiths Developmental Scales (N_pandemic = 16).</p></div><div><h3>Results</h3><p>The pandemic sample consistently underperformed in all four studies in comparison to pre-pandemic data. There was no evidence of developed word segmentation abilities at 12 months of age, and no successful word learning at 20 months of age. Lexical development between 12 and 24 months of age was lower than in the pre-pandemic sample, while social communication did not seem to be affected. At 30 months of age, the pandemic sample showed lower scores and lower mental age on the Language and Communication Griffiths' subscale, in comparison to the pre-pandemic data.</p></div><div><h3>Conclusions</h3><p>Infants born and raised during the pandemic have a poorer language development, that persists at least until 30 months of age.</p></div>","PeriodicalId":11435,"journal":{"name":"Early human development","volume":"195 ","pages":"Article 106081"},"PeriodicalIF":2.2,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0378378224001506/pdfft?md5=380499cb3d967e9e89d651eda870e356&pid=1-s2.0-S0378378224001506-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141757794","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"High threshold of total developmental quotient at 3 years for follow-up in extremely preterm infants","authors":"Takashi Maeda ,&nbsp;Yoshihiro Tanahashi ,&nbsp;Hideyuki Asada ,&nbsp;Hiroyuki Kidokoro ,&nbsp;Yoshiyuki Takahashi ,&nbsp;Yoshiaki Sato","doi":"10.1016/j.earlhumdev.2024.106098","DOIUrl":"10.1016/j.earlhumdev.2024.106098","url":null,"abstract":"<div><h3>Aim</h3><p>To investigate the relationship between the developmental quotient (DQ) at age 3 years and the need for educational support at school age in extremely preterm infants.</p></div><div><h3>Methods</h3><p>A total of 176 infants with a gestational age of &lt;28 weeks were analyzed. The total DQ and subscales were evaluated using the Kyoto Scale of Psychological Development (KSPD) test. Neurodevelopment at age 3 years was stratified using total DQ in a conventional (DQ &lt; 70 as developmental delay, DQ 70– &lt;85 as subnormal, DQ ≥85 as normal) and a modified way (subdividing normal into DQ 85– &lt;93 as low-normal and DQ ≥93 as high-normal). The prevalence of future educational support was compared for each stratum. Additionally, subscales were compared between those with and without educational support in each total DQ stratum.</p></div><div><h3>Results</h3><p>In conventional stratification, the prevalence of educational support was 32 (63 %) for developmental delay, 14 (24 %) for subnormal, and 10 (15 %) for normal. In modified stratification, the prevalence was 8 (26 %) for low-normal and 2 (5 %) for high-normal. While there was no significant difference in the odds of educational support between the normal and subnormal, the low-normal had significantly higher odds compared to the high-normal (OR 6.00; 95 % CI, 1.16–30.95, <em>p</em> = 0.03). Among the low-normal stratum, the language-social subscale was significantly lower in those with educational support.</p></div><div><h3>Conclusion</h3><p>Setting high thresholds for total DQ and evaluating detailed subscales at age 3 years may be useful for developmental follow-up in extremely preterm infants.</p></div>","PeriodicalId":11435,"journal":{"name":"Early human development","volume":"196 ","pages":"Article 106098"},"PeriodicalIF":2.2,"publicationDate":"2024-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0378378224001671/pdfft?md5=3a51223b1a6b924eac9c494db7c914a2&pid=1-s2.0-S0378378224001671-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141906188","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The relationship between digit ratio (2D:4D) and intelligence levels in specific learning disorders","authors":"Pınar AYDOĞAN AVŞAR ,&nbsp;Tayfun KARA ,&nbsp;Orhan KOCAMAN ,&nbsp;Merve AKKUŞ","doi":"10.1016/j.earlhumdev.2024.106085","DOIUrl":"10.1016/j.earlhumdev.2024.106085","url":null,"abstract":"<div><h3>Background</h3><p>Higher prenatal testosterone exposure regulates brain development and affects learning and intelligence directly. The digit ratio (2D:4D) is regarded as an indicator of prenatal testosterone exposure. This study aims to investigate the 2D:4D ratios and intelligence levels in individuals with specific learning disorders (SLD) and compare the ratios with healthy subjects.</p></div><div><h3>Methods</h3><p>The study included a total of 117 patients diagnosed with SLD and 67 healthy controls. We measured the 2D:4D ratios and administered the Wechsler-Intelligence Scale for Children-Revised to assess intelligence quotient (IQ) scores in the SLD group. Sociodemographic data was obtained for both patients and healthy subjects and compared in both groups, as well as 2D:4D ratios.</p></div><div><h3>Results</h3><p>Compared to healthy controls, both-hand 2D:4D ratios were found to be lower in the SLD group. In addition, male and female participants with SLD showed lower 2D:4D ratios in both hands than controls. The total scores on the WISC-R were found to decrease as the right-hand 2D:4D ratios and the age increased in the SLD group.</p></div><div><h3>Conclusion</h3><p>Our findings add to the literature examining the influence of prenatal testosterone exposure on learning and intelligence in the SLD sample. Further research in this domain may yield valuable insights into the underlying mechanisms and potential clinical implications for the management of SLDs examining additional variables that could potentially impact alongside the impact of sex hormones on brain development.</p></div>","PeriodicalId":11435,"journal":{"name":"Early human development","volume":"196 ","pages":"Article 106085"},"PeriodicalIF":2.2,"publicationDate":"2024-07-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141852123","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Circadian rhythm development in preterm infants. The role of postnatal versus postmenstrual age","authors":"R.B. Govindan ,&nbsp;Nickie N. Andescavage ,&nbsp;Sudeepta Basu ,&nbsp;Jonathan Murnick ,&nbsp;Julius Ngwa ,&nbsp;Jeffrey T. Galla ,&nbsp;Kushal Kapse ,&nbsp;Catherine Limperopoulos ,&nbsp;Adre du Plessis","doi":"10.1016/j.earlhumdev.2024.106084","DOIUrl":"10.1016/j.earlhumdev.2024.106084","url":null,"abstract":"<div><h3>Background, Aims</h3><p>Circadian rhythm maturation may be disturbed in premature infants undergoing neonatal intensive care. We used continuous heart rate recordings across the entire neonatal intensive care period to study circadian rhythm development in preterm infants and to evaluate the roles of postmenstrual (PMA) versus postnatal age (PNA).</p></div><div><h3>Materials and methods</h3><p>The circadian rhythm was calculated using a cosine fit of heart rate. The circadian rhythm amplitudes were averaged weekly and studied relative to PMA and PNA using the linear mixed effects models, adjusting for clinical variables that could affect the heart rate. The daily circadian rhythms were used to create grand averages for PMA groups: <span><math><mo>≤</mo></math></span>31, 32–35, and &gt; 35 weeks, and for PNA groups: <span><math><mo>≤</mo></math></span>30, 31–60, and &gt; 60 days.</p></div><div><h3>Results</h3><p>Sixty-six infants were evaluated as part of an ongoing prospective study with gestational ages between 23 and 36 weeks. The PMA (1.47 × 10⁻² beats per minute (bpm)/week, <em>P</em> = 2.07 × 10⁻⁸) and PNA (1.87 × 10⁻² bpm/day; <em>P</em> = 1.86 × 10⁻⁶) were significantly associated with the circadian rhythm amplitude independent of covariates. Infants <span><math><mo>≤</mo></math></span>31 weeks' PMA and <span><math><mo>≤</mo></math></span>30 days PNA, the phase of circadian rhythm amplitude grand averages showed a peak at night and a nadir during the day. Hereafter the circadian rhythm phase reversed to that established for mature individuals. The highest circadian rhythm amplitudes present &gt;35 weeks' PMA and &gt; 60 days PNA.</p></div><div><h3>Conclusions</h3><p>Our results indicate circadian rhythm matures with advancing gestation. The reversed circadian rhythm phase during the early postnatal period could be due to premature exposure to the ex-utero environment and warrant further study.</p></div>","PeriodicalId":11435,"journal":{"name":"Early human development","volume":"196 ","pages":"Article 106084"},"PeriodicalIF":2.2,"publicationDate":"2024-07-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141851860","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Trait mindfulness during pregnancy and maternal-infant bonding: Longitudinal associations with infant temperament and social-emotional development","authors":"Noor de Waal ,&nbsp;Paul Lodder ,&nbsp;Ivan Nyklíček ,&nbsp;Lianne P. Hulsbosch ,&nbsp;Marion I. van den Heuvel ,&nbsp;Katleen van der Gucht ,&nbsp;Elien de Caluwé ,&nbsp;Victor J.M. Pop ,&nbsp;Myrthe G.B.M. Boekhorst","doi":"10.1016/j.earlhumdev.2024.106082","DOIUrl":"10.1016/j.earlhumdev.2024.106082","url":null,"abstract":"<div><p>Maternal love and caregiving are pillars for optimal child development and may affect infant outcomes from pregnancy onwards. The present study aimed to examine whether maternal trait mindfulness during pregnancy and pre- and postnatal maternal-infant bonding were associated with maternal perceptions of infant temperament and social-emotional development. In total, 408 Dutch women (<em>M</em>_age = 31.33, <em>SD</em> = 3.59) participated in a prospective perinatal cohort study and completed questionnaires on trait mindfulness, prenatal bonding, postnatal bonding, infant temperament, and infant social-emotional development at 20 and 28 weeks of gestation, and 10 weeks, 6 and 12 months postpartum, respectively. Path analyses demonstrated that higher levels of the trait mindfulness facet non-judging (i.e., refraining from judgments about own feelings and thoughts) were associated with more pre- and postnatal maternal bonding and fewer social-emotional problems as perceived by the mother. Adopting an accepting and non-judgmental attitude may promote positive feelings of bonding and benefit the infant in terms of having fewer social-emotional problems in the first year of life. Mindfulness interventions may be offered to pregnant women in order to enhance maternal bonding and improve infant outcomes after birth.</p></div>","PeriodicalId":11435,"journal":{"name":"Early human development","volume":"196 ","pages":"Article 106082"},"PeriodicalIF":2.2,"publicationDate":"2024-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0378378224001518/pdfft?md5=dcbf651c290fd34c0ef5d2f3f6bc43f6&pid=1-s2.0-S0378378224001518-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141852476","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}