Current Biology最新文献_第6页

A deletion at the X-linked ARHGAP36 gene locus is associated with the orange coloration of tortoiseshell and calico cats. x连锁的ARHGAP36基因位点的缺失与玳瑁猫和印花布猫的橙色有关。

IF 8.1 1区生物学

Current Biology Pub Date : 2025-05-13 DOI: 10.1016/j.cub.2025.03.075

Hidehiro Toh, Wan Kin Au Yeung, Motoko Unoki, Yuki Matsumoto, Yuka Miki, Yumiko Matsumura, Yoshihiro Baba, Takashi Sado, Yasukazu Nakamura, Miho Matsuda, Hiroyuki Sasaki

{"title":"A deletion at the X-linked ARHGAP36 gene locus is associated with the orange coloration of tortoiseshell and calico cats.","authors":"Hidehiro Toh, Wan Kin Au Yeung, Motoko Unoki, Yuki Matsumoto, Yuka Miki, Yumiko Matsumura, Yoshihiro Baba, Takashi Sado, Yasukazu Nakamura, Miho Matsuda, Hiroyuki Sasaki","doi":"10.1016/j.cub.2025.03.075","DOIUrl":"https://doi.org/10.1016/j.cub.2025.03.075","url":null,"abstract":"The X-linked orange (O) locus in domestic cats controls an unknown molecular mechanism that causes the suppression of black-brownish pigmentation in favor of orange coloration. The alternating black-brownish and orange patches seen in tortoiseshell and calico cats are considered classic examples of the phenotypic expression of random X chromosome inactivation (XCI) occurring in female mammals. However, the O gene in the cat genome has not been identified, and the genetic variation responsible for the orange coloration remains unknown. We report here that a 5.1-kilobase (kb) deletion within an intron of the X-linked ARHGAP36 gene, encoding a Rho GTPase-activating protein, is closely and exclusively associated with orange coloration. The deleted region contains a highly conserved putative regulatory element, whose removal is presumed to alter ARHGAP36 expression. Notably, ARHGAP36 expression in cat skin tissues is linked to the suppression of many melanogenesis genes, potentially shifting pigment synthesis from eumelanin to pheomelanin. Furthermore, we find evidence that the gene undergoes XCI in female human and mouse cells and XCI-dependent CpG island methylation consistent with random XCI in female domestic cats. The 5.1-kb deletion seems widespread in domestic cats with orange coat coloration, suggesting a single origin of this coat color phenotype.","PeriodicalId":11359,"journal":{"name":"Current Biology","volume":" ","pages":""},"PeriodicalIF":8.1,"publicationDate":"2025-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144085733","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Discovery of a novel flagellar filament system underpinning Leishmania adhesion to surfaces. 发现一种新的鞭毛细丝系统，支持利什曼原虫对表面的粘附。

IF 8.1 1区生物学

Current Biology Pub Date : 2025-05-13 DOI: 10.1016/j.cub.2025.04.064

Barrack O Owino, Ryuji Yanase, Alan O Marron, Flavia Moreira-Leite, Sue Vaughan, Jack D Sunter

{"title":"Discovery of a novel flagellar filament system underpinning Leishmania adhesion to surfaces.","authors":"Barrack O Owino, Ryuji Yanase, Alan O Marron, Flavia Moreira-Leite, Sue Vaughan, Jack D Sunter","doi":"10.1016/j.cub.2025.04.064","DOIUrl":"https://doi.org/10.1016/j.cub.2025.04.064","url":null,"abstract":"Adhesion to surfaces is a common strategy employed across biology, especially by pathogens. Within their sand fly vector, Leishmania parasites undergo multiple developmental stages, including the understudied haptomonad form, which adheres to the sand fly stomodeal valve via a highly modified flagellum. This adhesion, likely critical for efficient transmission, is mediated by a complex adhesion plaque from which filaments in the modified flagellum extend toward the cell body and likely connect to the flagellum attachment zone (FAZ), a cytoskeletal structure important for cell morphogenesis. However, the role of the FAZ in adhesion and its relationship with the kinetoplastid-insect adhesion proteins (KIAPs) and the filamentous structures of the plaque itself remain unclear. Here, to examine the role of the FAZ in adhesion, we generated FAZ2, FAZ5, and FAZ34 deletion mutants. Deletion of any of these FAZ proteins impaired parasite adhesion in vitro. Furthermore, we identified a novel and distinct set of extra-axonemal flagellar filaments important for adhesion and demonstrated that KIAP2 is an essential component of these filaments. Our findings underscore the importance of a robust connection from the cell body to the adhesion plaque for stable Leishmania adhesion via the highly modified flagellum.","PeriodicalId":11359,"journal":{"name":"Current Biology","volume":" ","pages":""},"PeriodicalIF":8.1,"publicationDate":"2025-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144119180","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Molecular and genetic characterization of sex-linked orange coat color in the domestic cat. 家猫性别连锁橙色毛色的分子和遗传特征。

IF 8.1 1区生物学

Current Biology Pub Date : 2025-05-12 DOI: 10.1016/j.cub.2025.04.055

Christopher B Kaelin, Kelly A McGowan, Joshaya C Trotman, Donald C Koroma, Victor A David, Marilyn Menotti-Raymond, Emily C Graff, Anne Schmidt-Küntzel, Elena Oancea, Gregory S Barsh

{"title":"Molecular and genetic characterization of sex-linked orange coat color in the domestic cat.","authors":"Christopher B Kaelin, Kelly A McGowan, Joshaya C Trotman, Donald C Koroma, Victor A David, Marilyn Menotti-Raymond, Emily C Graff, Anne Schmidt-Küntzel, Elena Oancea, Gregory S Barsh","doi":"10.1016/j.cub.2025.04.055","DOIUrl":"10.1016/j.cub.2025.04.055","url":null,"abstract":"The Sex-linked orange mutation in domestic cats causes variegated patches of reddish/yellow hair and is a defining signature of random X inactivation in female tortoiseshell and calico cats. Unlike the situation for most coat color genes, there is no apparent homolog for Sex-linked orange in other mammals. We show that Sex-linked orange is caused by a 5-kb deletion that leads to ectopic and melanocyte-specific expression of the Rho GTPase Activating Protein 36 (Arhgap36) gene. Single-cell RNA sequencing (RNA-seq) studies from fetal cat skin reveal that red/yellow hair color is caused by reduced expression of melanogenic genes that are normally activated by the melanocortin 1 receptor (Mc1r)-cyclic adenosine monophosphate (cAMP)-protein kinase A (PKA) pathway, but Mc1r and its ability to stimulate cAMP accumulation is intact. Instead, we show that expression of Arhgap36 in melanocytes leads to reduced levels of the PKA catalytic subunit (PKAC); thus, Sex-linked orange is genetically and biochemically downstream of Mc1r. Our findings resolve a longstanding comparative genetic puzzle, provide in vivo evidence for the ability of Arhgap36 to inhibit PKA, and reveal a molecular explanation for a charismatic color pattern with a rich genetic history.","PeriodicalId":11359,"journal":{"name":"Current Biology","volume":" ","pages":""},"PeriodicalIF":8.1,"publicationDate":"2025-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144085761","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Conscious tactile perception entails distinct neural dynamics within somatosensory areas. 有意识的触觉知觉需要躯体感觉区域内不同的神经动力学。

IF 8.1 1区生物学

Current Biology Pub Date : 2025-05-12 DOI: 10.1016/j.cub.2025.04.052

Davide Albertini, Maria Del Vecchio, Ivana Sartori, Andrea Pigorini, Francesca Talami, Flavia Maria Zauli, Simone Sarasso, Ezequiel Pablo Mikulan, Marcello Massimini, Pietro Avanzini

{"title":"Conscious tactile perception entails distinct neural dynamics within somatosensory areas.","authors":"Davide Albertini, Maria Del Vecchio, Ivana Sartori, Andrea Pigorini, Francesca Talami, Flavia Maria Zauli, Simone Sarasso, Ezequiel Pablo Mikulan, Marcello Massimini, Pietro Avanzini","doi":"10.1016/j.cub.2025.04.052","DOIUrl":"https://doi.org/10.1016/j.cub.2025.04.052","url":null,"abstract":"Distilling the neural correlates of consciousness (NCCs) in humans is challenging due to limitations in the spatiotemporal resolution of recording techniques and confounds related to pre- and post-perceptual processes. In this study, we leveraged the detailed insights provided by human intracortical recordings to elucidate how somatosensory responses to simple tactile stimuli vary across different stimulus intensities and reporting conditions. Among the various spatiotemporal components of somatosensory processing, we observed tonic responses in posterior perisylvian regions that exhibited all the key characteristics of somatosensory NCCs. These responses remained invariant regardless of reporting, displayed an all-or-nothing pattern at the verge of the sensory threshold, and showed the most pronounced divergence between perceived and non-perceived stimuli. Overall, our findings indicate that conscious perception of simple tactile stimuli depends on higher-order somatosensory regions and that sustained neural dynamics in these areas may serve as an organizational principle of somatosensory awareness.","PeriodicalId":11359,"journal":{"name":"Current Biology","volume":" ","pages":""},"PeriodicalIF":8.1,"publicationDate":"2025-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144085738","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Neofunctionalization of VAMP7 opened up a plant-unique vacuolar transport pathway. VAMP7的新功能化开辟了一条植物特有的液泡运输途径。

IF 8.1 1区生物学

Current Biology Pub Date : 2025-05-09 DOI: 10.1016/j.cub.2025.04.062

Masaru Fujimoto, Yutaro Shimizu, Yoko Ito, Kazuo Ebine, Naoki Minamino, Takehiko Kanazawa, Yoichiro Fukao, Akihiko Nakano, Tomohiro Uemura, Takashi Ueda

{"title":"Neofunctionalization of VAMP7 opened up a plant-unique vacuolar transport pathway.","authors":"Masaru Fujimoto, Yutaro Shimizu, Yoko Ito, Kazuo Ebine, Naoki Minamino, Takehiko Kanazawa, Yoichiro Fukao, Akihiko Nakano, Tomohiro Uemura, Takashi Ueda","doi":"10.1016/j.cub.2025.04.062","DOIUrl":"https://doi.org/10.1016/j.cub.2025.04.062","url":null,"abstract":"Each eukaryotic cell possesses a specialized membrane trafficking system that emerged through paralogous expansion followed by the neofunctionalization of trafficking machinery components, including soluble N-ethylmaleimide sensitive factor attachment protein receptor (SNARE) proteins, during evolution. We discovered that the acquisition of an acidic insertion in the polypeptide converted the secretory R-SNARE vesicle-associated membrane protein (VAMP)72 into a major component of plant vacuolar transport. The moderately acidic insertion, originating from alternative splicing in the common ancestor of zygnematophytes and embryophytes, conferred binding ability to the clathrin adapter protein complex-4 (AP-4) at the trans-Golgi network (TGN), partially redirecting the VAMP72 protein from the secretory to the vacuolar transport pathway. Increased acidity of the insertion in angiosperms further reinforced the interaction with AP-4, leading VAMP727 to discrete zoning during sorting at the TGN and a definitive conversion to endosomal localization. This stepwise neofunctionalization of VAMP72 provided an option for the development of the intricate and complex vacuolar transport system in extant angiosperms.","PeriodicalId":11359,"journal":{"name":"Current Biology","volume":" ","pages":""},"PeriodicalIF":8.1,"publicationDate":"2025-05-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144076652","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Dominance rank inference in mice via chemosensation. 基于化学感觉的小鼠优势等级推断。

IF 8.1 1区生物学

Current Biology Pub Date : 2025-05-09 DOI: 10.1016/j.cub.2025.04.063

Neven Borak, Patty Wai, Paula Rodriguez Villamayor, Phoebe M Claxton, Swang Liang, Johannes Kohl

{"title":"Dominance rank inference in mice via chemosensation.","authors":"Neven Borak, Patty Wai, Paula Rodriguez Villamayor, Phoebe M Claxton, Swang Liang, Johannes Kohl","doi":"10.1016/j.cub.2025.04.063","DOIUrl":"https://doi.org/10.1016/j.cub.2025.04.063","url":null,"abstract":"Social dominance hierarchies enable efficient resource allocation and conflict avoidance in animal communities.1 Individuals can determine their relative status by tracking previous conflict outcomes, as seen in aggression training2 and the winner effect,3,4 where successive wins increase the likelihood of future victories. Repeated optogenetic stimulation of the dorsomedial prefrontal cortex (dmPFC) results in lasting rank increases,5 suggesting that social rank is derived as a statistic of past outcomes. However, relative rank could be assessed more efficiently by incorporating information about an opponent's dominance status. Pheromone signals, such as darcin, are enriched in the urine of dominant individuals,6,7,8,9 suggesting that hierarchical behavior may integrate information about both own and opponent rank. Although prior studies have explored the learning and neural representation of own rank,5,10,11 how opponent rank is detected and encoded remains unclear. Here, we address this question in male mice using a tube test assay. We show that stable hierarchies do not rely on fixed behavioral traits and that mice can infer the rank of unfamiliar opponents by detecting scalable chemosensory rank cues. Sensory ablation experiments reveal that both olfactory and vomeronasal cues are sufficient for rank assessment. Male mice thus use chemosensory signals to infer dominance status during social interactions.","PeriodicalId":11359,"journal":{"name":"Current Biology","volume":" ","pages":""},"PeriodicalIF":8.1,"publicationDate":"2025-05-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144110196","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Positive feedback from woodpeckers on deadwood decomposition via invertebrates. 啄木鸟对通过无脊椎动物分解腐木的积极反馈。

IF 8.1 1区生物学

Current Biology Pub Date : 2025-05-08 DOI: 10.1016/j.cub.2025.04.041

Bin Tuo, Li Lin, Reinier S van Rantwijk, Richard S P van Logtestijn, Leo Goudzwaard, Kamiel Scheffers, Matty P Berg, Mariet M Hefting, Ute Sass-Klaassen, Juan Zuo, Chao Guo, Johannes H C Cornelissen

{"title":"Positive feedback from woodpeckers on deadwood decomposition via invertebrates.","authors":"Bin Tuo, Li Lin, Reinier S van Rantwijk, Richard S P van Logtestijn, Leo Goudzwaard, Kamiel Scheffers, Matty P Berg, Mariet M Hefting, Ute Sass-Klaassen, Juan Zuo, Chao Guo, Johannes H C Cornelissen","doi":"10.1016/j.cub.2025.04.041","DOIUrl":"10.1016/j.cub.2025.04.041","url":null,"abstract":"Plant matter decomposition is a linchpin of global carbon cycling,1,2 yet the role of vertebrates remains poorly understood.3 Woodpeckers are ubiquitous vertebrate inhabitants of forests, where they hack into deadwood to forage for small animals. Our study in a temperate forest revealed not only how this behavior significantly impacts deadwood decomposition through mechanical breakdown but also how its species specificity leads to positive feedback on decomposition rates. Investigating large logs from six conifer species over 6 years in a tree cemetery, we found that woodpeckers accelerated decomposition (both mass and volume losses) selectively in softer, more decomposable deadwood like that of Norway spruce (Picea abies), which hosted abundant wood-boring beetle larvae relative to the abundances in other tree species. This selectivity triggers a positive feedback loop: bottom-up drivers (low wood density and high water-holding capacity) foster abundant invertebrate prey, promoting top-down woodpecker foraging that fragments logs and exposes inner tissues to microbial decay. Positioning woodpeckers as a potential keystone wood decay agent, our study supports the growing call for integrating vertebrate contributions into global carbon cycling models.4 As the first study to elucidate the complex interactions between deadwood traits, invertebrate populations, and woodpecker activities, we aim to galvanize further research into their often-overlooked functional role as deadwood fragmenters. The conservation implications of these findings are profound, especially in light of the historical context where vertebrates that once performed key ecological functions are now endangered or extinct due to widespread anthropogenic activities.5,6,7,8,9.","PeriodicalId":11359,"journal":{"name":"Current Biology","volume":" ","pages":""},"PeriodicalIF":8.1,"publicationDate":"2025-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143998386","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Expression of clock genes tracks daily and tidal time in brains of intertidal crustaceans Eurydice pulchra and Parhyale hawaiensis. 时钟基因在潮间带甲壳类动物Eurydice pulchra和Parhyale hawaiensis脑中的表达跟踪每日和潮汐时间。

IF 8.1 1区生物学

Current Biology Pub Date : 2025-05-08 DOI: 10.1016/j.cub.2025.04.047

Andrew Oliphant, Chee Y Sia, Charalambos P Kyriacou, David C Wilcockson, Michael H Hastings

{"title":"Expression of clock genes tracks daily and tidal time in brains of intertidal crustaceans Eurydice pulchra and Parhyale hawaiensis.","authors":"Andrew Oliphant, Chee Y Sia, Charalambos P Kyriacou, David C Wilcockson, Michael H Hastings","doi":"10.1016/j.cub.2025.04.047","DOIUrl":"https://doi.org/10.1016/j.cub.2025.04.047","url":null,"abstract":"Intertidal organisms, such as the crustaceans Eurydice pulchra and Parhyale hawaiensis, express daily and tidal rhythms of physiology and behavior to adapt to their temporally complex environments. Although the molecular-genetic basis of the circadian clocks driving daily rhythms in terrestrial animals is well understood, the nature of the circatidal clocks driving tidal rhythms remains a mystery. Using in situ hybridization, we identified discrete clusters of ∼60 putative \"clock\" cells co-expressing canonical circadian clock genes across the protocerebrum of E. pulchra and P. hawaiensis brains. In field-collected, tidally rhythmic E. pulchra sampled under a light:dark (LD) cycle, the expression of period (per) and cryptochrome 2 (cry2) exhibited daily rhythms in particular cell groups, whereas timeless (tim) showed 12-h rhythms in others. In tidally rhythmic laboratory-reared P. hawaiensis, previously entrained to 12.4-h cycles of agitation under LD and sampled under continuous darkness, several cell groups (e.g., medioposterior cells) exhibited circadian expression of per and cry2. In contrast, dorsal-lateral cells in the protocerebrum exhibited robust ∼12-h, i.e., circatidal, rhythms of per and cry2, phased to the prior tidal agitation but not the prior LD. In P. hawaiensis exhibiting daily behavior under LD without tidal agitation, robust daily rhythms of per and cry2 expression were evident in medioposterior and other cells, whereas expression in dorsal-lateral cells was not rhythmic, underlining their essentially tidal periodicity. These results implicate canonical circadian molecules in circatidal timekeeping and reveal conserved brain networks as potential neural substrates for the generation of daily and tidal rhythms appropriate to intertidal habitats.","PeriodicalId":11359,"journal":{"name":"Current Biology","volume":" ","pages":""},"PeriodicalIF":8.1,"publicationDate":"2025-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143984964","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The expanded Bostrychia moritziana genome unveils evolution in the most diverse and complex order of red algae. 扩大的moritziana Bostrychia基因组揭示了红藻最多样化和最复杂的进化顺序。

IF 8.1 1区生物学

Current Biology Pub Date : 2025-05-07 DOI: 10.1016/j.cub.2025.04.044

Romy Petroll, John A West, Michael Ogden, Owen McGinley, Rory J Craig, Susana M Coelho, Michael Borg

{"title":"The expanded Bostrychia moritziana genome unveils evolution in the most diverse and complex order of red algae.","authors":"Romy Petroll, John A West, Michael Ogden, Owen McGinley, Rory J Craig, Susana M Coelho, Michael Borg","doi":"10.1016/j.cub.2025.04.044","DOIUrl":"https://doi.org/10.1016/j.cub.2025.04.044","url":null,"abstract":"Red algae are an ancient eukaryotic lineage that were among the first to evolve multicellularity. Although they share a common origin with modern-day plants and display complex multicellular development, comprehensive genome data from the most highly evolved red algal groups remain scarce. Here, we present a chromosome-level genome assembly of Bostrychia moritziana, a complex red seaweed in the Rhodomelaceae family of the Ceramiales-the largest and most diverse order of red algae. Contrary to the view that red algal genomes are typically small, we report significant genome size expansion in Bostrychia and other Ceramiales, which represents one of at least three independent expansion events in red algal evolution. Our analyses suggest that these expansions do not involve polyploidy or ancient whole-genome duplications, but in Bostrychia rather stem from the proliferation of a single lineage of giant Plavaka DNA transposons. Consistent with its enlarged genome, Bostrychia has an increased gene content shaped by de novo gene emergence and amplified gene families in common with other Ceramiales, providing insight into the genetic adaptations underpinning this successful and species-rich order. Finally, our sex-specific assemblies resolve the UV sex chromosomes in Bostrychia, which feature expanded gene-rich sex-linked regions. Notably, each sex chromosome harbors a three amino acid loop extension homeodomain (TALE-HD) transcription factor orthologous to ancient regulators of haploid-diploid transitions in other multicellular lineages. Together, our findings offer a unique perspective of the genomic adaptations driving red algal diversity and demonstrate how this red seaweed lineage can provide insight into the evolutionary origins and universal principles underpinning complex multicellularity.","PeriodicalId":11359,"journal":{"name":"Current Biology","volume":" ","pages":""},"PeriodicalIF":8.1,"publicationDate":"2025-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144062851","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Memory and the scheduling of parental care in an insect population in the wild. 野外昆虫种群的记忆与亲代抚育的安排。

IF 8.1 1区生物学

Current Biology Pub Date : 2025-05-07 DOI: 10.1016/j.cub.2025.04.045

Jeremy Field, Charlie Savill, William A Foster

{"title":"Memory and the scheduling of parental care in an insect population in the wild.","authors":"Jeremy Field, Charlie Savill, William A Foster","doi":"10.1016/j.cub.2025.04.045","DOIUrl":"https://doi.org/10.1016/j.cub.2025.04.045","url":null,"abstract":"Animals are expected to schedule their activities so as to maximize fitness. Vertebrates achieve this using memories of previous events-what happened, where, and when1,2-but most studies have been lab based.3 Here, we investigate the scheduling of parental care by progressively provisioning digger wasps (Ammophila) in their natural environment, where fitness consequences are observable and we can relate behavior to its ecological context. Despite their miniature brains, females used information including all three elements of the what-where-when paradigm. Remarkably, they remember the locations of up to 9 separate nests simultaneously (where), each nest containing a single offspring. Without having to resample, females feed offspring in order of age (when), reducing the chance of starvation, and can adjust the sequence flexibly. Memory capacity might sometimes constrain performance: offspring were fed out of order when there were more of them to choose between or if the age sequence was altered following offspring deaths. Mothers delayed feeding offspring that had been given larger first food items experimentally (what), enabling them to initiate additional offspring earlier, but in this case decisions were based on resampling offspring needs directly rather than on memories of the food provided during egg-laying. Resampling could reflect ecological pressures rather than cognitive constraints: mothers relied on memory if resampling would expose offspring to parasites but resampled when risks were reduced. Progressive provisioning requires mothers to coordinate the feeding of multiple offspring and assess offspring maternity and needs during development. These skills may have preadapted some lineages for sociality.","PeriodicalId":11359,"journal":{"name":"Current Biology","volume":" ","pages":""},"PeriodicalIF":8.1,"publicationDate":"2025-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143957903","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0