Diagnostic Cytopathology最新文献

Study on the Application Value of Colloidal Gold Immunochromatography Assay Combined With Fine Needle Aspiration Biopsy for Identifying Lymph Node Metastasis in Papillary Thyroid Carcinoma. 胶体金免疫层析联合细针穿刺活检鉴别甲状腺乳头状癌淋巴结转移的应用价值研究。

IF 1 4区医学

Diagnostic Cytopathology Pub Date : 2025-07-19 DOI: 10.1002/dc.25498

Mingfeng Mao, Binqian Zhou, Xuejing Zhang, Xinjia Liu, Hongling Li, Jiaming Zhang

{"title":"Study on the Application Value of Colloidal Gold Immunochromatography Assay Combined With Fine Needle Aspiration Biopsy for Identifying Lymph Node Metastasis in Papillary Thyroid Carcinoma.","authors":"Mingfeng Mao, Binqian Zhou, Xuejing Zhang, Xinjia Liu, Hongling Li, Jiaming Zhang","doi":"10.1002/dc.25498","DOIUrl":"https://doi.org/10.1002/dc.25498","url":null,"abstract":"Purpose: To investigate the accuracy of a colloidal gold immunochromatography assay (GICA) for thyroglobulin detection and evaluate the diagnostic performance of the combined GICA and fine-needle aspiration biopsy (FNAB) methods in identifying lymph node metastasis among patients with papillary thyroid carcinoma (PTC).Methods: Out of 97 PTC patients with suspicious cervical lymph nodes determined by the postoperative pathological diagnosis or the ultrasound-directed biopsy were chosen between January 2021 and October 2023. A total of 104 suspicious lymph nodes were detected via the GICA methods and the combined GICA and FNAB methods, respectively. The histological results were used as the gold standard. The accuracy and diagnostic performance were analyzed on the basis of the receiver operating characteristic curves.Results: Among the 104 lymph nodes, 85 were positive and 19 were negative. For GICA methods, 47.92 ng/mL was the optimal cutoff value with a sensitivity of 93.98% and a specificity of 90.48% in the diagnosis of lymph node metastases. The accuracy of FNAB was 88.46%. The combined GICA and FNAB approach yielded an accuracy of 95.19%, a sensitivity of 96.39%, and a specificity of 90.48%.Conclusion: GICA methods appeared to have high sensitivity and specificity for quickly diagnosing suspicious lymph nodes. The combined application of GICA and FNAB methods could improve the accuracy of the preoperative diagnosis and performed exceptionally well in diagnostic performance, providing a new convenient pathway for identifying lymph node metastases in clinical settings.","PeriodicalId":11349,"journal":{"name":"Diagnostic Cytopathology","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2025-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144667331","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cytopathology in India: Past, Present, and Future. 印度的细胞病理学：过去、现在和未来。

IF 1 4区医学

Diagnostic Cytopathology Pub Date : 2025-07-13 DOI: 10.1002/dc.25503

Jitendra Singh Nigam, Jyotsna Naresh Bharti, Ashutosh Rath, Immanuel Pradeep, Biswajit Dey, Ravi Mehrotra

{"title":"Cytopathology in India: Past, Present, and Future.","authors":"Jitendra Singh Nigam, Jyotsna Naresh Bharti, Ashutosh Rath, Immanuel Pradeep, Biswajit Dey, Ravi Mehrotra","doi":"10.1002/dc.25503","DOIUrl":"https://doi.org/10.1002/dc.25503","url":null,"abstract":"Cytopathology was apparent as a feasible and inexpensive screening and diagnostic technique incorporated in India during the 1950s and 1960s. The Indian Academy of Cytologists (IAC) was established to foster cytology research, standardize nomenclature, and advance cytology across India. Although cytopathology is a fundamental component of the postgraduate pathology curriculum, numerous challenges and limitations impede its practice in India, including a shortage of trained cytopathologists, uneven distribution of cytopathology services and their quality assurance, and financial constraints for advanced diagnostics in cytopathology samples. These obstacles hinder the efficient execution of cytopathology activities in India. This review outlines the historical evolution, expansion, institutional and academic advancements, cytology-based screening programs and guidelines, quality assurance, research output, and contemporary developments in cytopathology reporting, as well as the challenges and limitations encountered by cytopathology practice in India. The review argues for intentional initiatives to augment the capability of cytopathology in remote and rural regions of India, facilitating early and improved cancer detection and patient outcomes.","PeriodicalId":11349,"journal":{"name":"Diagnostic Cytopathology","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2025-07-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144625519","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Effect of Uterine Manipulator on Peritoneal Cytology Positivity in Endometrial Cancer: A Prospective Observational Study. 子宫操纵器对子宫内膜癌腹膜细胞学阳性的影响：一项前瞻性观察研究。

IF 1 4区医学

Diagnostic Cytopathology Pub Date : 2025-07-13 DOI: 10.1002/dc.25497

Ceren Gerçek, Hande Nur Öncü, Tuğba Taşkın Türkmenoğlu, Candost Hanedan, Vakkas Korkmaz

{"title":"The Effect of Uterine Manipulator on Peritoneal Cytology Positivity in Endometrial Cancer: A Prospective Observational Study.","authors":"Ceren Gerçek, Hande Nur Öncü, Tuğba Taşkın Türkmenoğlu, Candost Hanedan, Vakkas Korkmaz","doi":"10.1002/dc.25497","DOIUrl":"https://doi.org/10.1002/dc.25497","url":null,"abstract":"Aim: There are studies suggesting that the use of a uterine manipulator during minimally invasive surgery (MIS) may lead to tumor spread in endometrial cancer patients, and there is no clear consensus on the safety of uterine manipulator use. The aim of this study was to investigate the effect of uterine manipulator use on peritoneal cytology (PC) results obtained before and after hysterectomy in endometrial cancer patients.Methods: A single-center, prospective observational study was conducted, including 108 patients who were diagnosed with endometrial cancer and underwent surgical intervention. The patients were divided into three groups: Group 1 (n = 36), total abdominal hysterectomy (TAH); Group 2 (n = 41) laparoscopic hysterectomy with intrauterine manipulator (TLH with IUM); and Group 3 (n = 31) laparoscopic hysterectomy without IUM (TLH without IUM). PC samples were taken before and after the hysterectomy, and cytology results were compared among the groups.Results: Of the 108 patients included in the study, 33.3% (36/108) were in Group 1, 38% (41/108) were in Group 2, and 28.7% (31/108) were in Group 3. The clinical and demographic data among the groups were similar (p > 0.05). PC was positive in six of the 108 patients. In the TLH with IUM group, one patient with a negative cytology sample before the manipulation showed a positive result after the hysterectomy.Conclusions: Although statistical significance was not reached, utilizing an IUM to manage endometrial cancer with MIS may enhance cytology positivity. This finding requires further validation through larger prospective studies.","PeriodicalId":11349,"journal":{"name":"Diagnostic Cytopathology","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2025-07-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144625520","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Panel Testing of BRAF Mutation, RAS Mutation, and RET/PTC Rearrangements or RET Mutation Using Fine-Needle Aspiration Specimens in Evaluation of Thyroid Carcinoma. 使用细针穿刺标本评估甲状腺癌的BRAF突变、RAS突变、RET/PTC重排或RET突变的小组检测

IF 1 4区医学

Diagnostic Cytopathology Pub Date : 2025-07-05 DOI: 10.1002/dc.25500

Zhaohui Zhu, Hailei Tong, Xu Qian, Meiling Xue, Aijun Sun, Yifei Yin, Weimin Sun, Ling Mao

{"title":"Panel Testing of BRAF Mutation, RAS Mutation, and RET/PTC Rearrangements or RET Mutation Using Fine-Needle Aspiration Specimens in Evaluation of Thyroid Carcinoma.","authors":"Zhaohui Zhu, Hailei Tong, Xu Qian, Meiling Xue, Aijun Sun, Yifei Yin, Weimin Sun, Ling Mao","doi":"10.1002/dc.25500","DOIUrl":"https://doi.org/10.1002/dc.25500","url":null,"abstract":"Objective: Thyroid carcinoma (TC) is a common malignancy of the endocrine system. This research investigates the value of multiple gene detection in evaluating the pathological features of TC.Methods: This retrospective study includes samples from 213 participants who underwent fine-needle aspiration, among whom 176 were diagnosed as TC and 37 with benign lesions. All patients underwent polygenic (BRAF, RAS, and RET) mutation detection. The surgical and pathological results were used as the gold standard to analyze the correlation between different gene mutations.Results: The diagnostic accuracy and sensitivity of multigene panel testing were remarkably superior to those of BRAF, RAS, and RET alone, whereas the omission diagnosis rate was lower than that of BRAF, RAS, and RET alone. The diagnostic area under the curve of BRAF, RAS, RET, and combined detection for TC was 0.8871, 0.5468, 0.5717, and 0.9396, respectively; RAS and RET gene mutation was closely related to the lymph node metastasis of the enrolled patients (p < 0.05). Mutation status for both single-gene testing and multigene panel testing closely correlated with the histological subtype of the patients.Conclusion: While BRAF mutations are associated with papillary TC, RAS mutations are more common in follicular TC, and RET mutations are common in medullary TC. Combined detection of RAS and RET gene mutations in TC has a certain correlation with the disease's pathological characteristics, which provides new ideas and measures for the subsequent diagnosis and evaluation of TC.","PeriodicalId":11349,"journal":{"name":"Diagnostic Cytopathology","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2025-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144567279","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Targetable Molecular Profiles in Salivary Duct Carcinoma: A Review and Case Study of Molecular Diagnostic and Therapeutic Implications. 涎腺导管癌的靶向分子特征：分子诊断和治疗意义的回顾和案例研究。

IF 1 4区医学

Diagnostic Cytopathology Pub Date : 2025-07-04 DOI: 10.1002/dc.25501

Gloria Hopkins Sura

{"title":"Targetable Molecular Profiles in Salivary Duct Carcinoma: A Review and Case Study of Molecular Diagnostic and Therapeutic Implications.","authors":"Gloria Hopkins Sura","doi":"10.1002/dc.25501","DOIUrl":"https://doi.org/10.1002/dc.25501","url":null,"abstract":"Salivary duct carcinoma is a rare, high-grade malignancy of the salivary glands, most commonly arising in the parotid. This review highlights recent advancements in the cytologic, immunophenotypic, and molecular characterization of salivary duct carcinoma, emphasizing the central role of biomarkers such as androgen receptor (AR) overexpression and ERBB2 (HER2) amplification in diagnosis, prognosis, and therapeutic decision-making. These principles are illustrated through the case of a 55-year-old male with AR-positive, HER2-amplified salivary duct carcinoma of the right parotid gland with nodal and osseous metastases. Diagnosis was established via fine-needle aspiration (FNA) cytology, immunocytochemistry, and molecular profiling. The patient underwent androgen deprivation therapy followed by treatment with a HER2 targeted antibody-drug conjugate, achieving disease stability. This case exemplifies how molecular diagnostics inform personalized treatment strategies in salivary duct carcinoma and underscores the need for standardized testing protocols and greater awareness of precision oncology approaches in salivary gland malignancies.","PeriodicalId":11349,"journal":{"name":"Diagnostic Cytopathology","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2025-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144559502","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cytological Assessment of Metastatic Gastrointestinal Stromal Tumor in Ascitic Fluid. 腹水中转移性胃肠道间质瘤的细胞学评估。

IF 1 4区医学

Diagnostic Cytopathology Pub Date : 2025-06-24 DOI: 10.1002/dc.25499

Hadi Sultan, Zohre Sadeghian, Elvia Goez-Gutierrez, M Julia Diacovo, Esther Yoon

引用次数: 0

BAP1 Loss on Immunocytochemistry and Its Association With Monosomy 3 in Uveal Melanoma Fine-Needle Aspirations. 葡萄膜黑色素瘤细针穿刺中BAP1免疫细胞化学缺失及其与单体3的关系

IF 1 4区医学

Diagnostic Cytopathology Pub Date : 2025-06-17 DOI: 10.1002/dc.25496

Precious Ann Fortes, Michelle Nguyen, Po Chu Fung, Erika F Rodriguez, Teresa H Kim, Kosuke Kawai, Neda A Moatamed

{"title":"BAP1 Loss on Immunocytochemistry and Its Association With Monosomy 3 in Uveal Melanoma Fine-Needle Aspirations.","authors":"Precious Ann Fortes, Michelle Nguyen, Po Chu Fung, Erika F Rodriguez, Teresa H Kim, Kosuke Kawai, Neda A Moatamed","doi":"10.1002/dc.25496","DOIUrl":"10.1002/dc.25496","url":null,"abstract":"Background: Loss of nuclear BRCA1-associated protein 1 (nBAP1) expression is strongly linked to monosomy 3 in uveal melanoma. While fine-needle aspiration (FNA) aids diagnosis, the prognostic value of nBAP1 immunocytochemistry (ICC) is still being investigated. This study examines the correlation between nBAP1 loss on ICC and fluorescence in situ hybridization (FISH) findings, as well as its clinical impact.Methods: Intraocular FNA cytology specimens with clinical concern for uveal melanoma from April 2015 to March 2023 with available nBAP1 ICC, FISH results, and clinical follow-up were examined. Two independent reviewers, blinded to the cytogenetic results, interpreted the nBAP1 ICC as either loss or retained. Statistical analysis using Fisher's exact test was utilized to evaluate the relationship between nBAP1 loss on ICC and FISH findings. Kaplan-Meier survival plots were constructed to examine the metastasis-free survival.Results: Among the 79 cases included in the study, 86.1% (68/79) showed nBAP1 loss. Approximately 63.2% of patients with nBAP1 loss had monosomy 3, whereas none with nBAP1 retained had monosomy 3 (p < 0.001). Of the nBAP1 loss cases, 41.2% (28/68) had monosomy 3 alone, while 22.1% (15/68) had both monosomy 3 and 6p gain. Patients with nBAP1 loss had a significantly higher risk of metastasis (p ≤ 0.04), with a 5-year metastasis-free survival of 57.1% versus 100% in nBAP1 retained cases.Conclusion: BAP1 ICC is a cost-effective prognostic tool in uveal melanoma FNAs, strongly correlating with monosomy 3 and poor outcomes. Integrating BAP1 ICC with FISH enhances risk stratification, enabling earlier identification of high-risk patients and guiding treatment decisions.","PeriodicalId":11349,"journal":{"name":"Diagnostic Cytopathology","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2025-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12265483/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144316174","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Spectrum of Polyoma Virus and Polyoma Virus-Like Changes in Urine Cytology: When Should an Atypical Diagnosis Be Considered. 尿细胞学中多瘤病毒和多瘤病毒样改变的谱：何时应考虑非典型诊断。

IF 1 4区医学

Diagnostic Cytopathology Pub Date : 2025-06-09 DOI: 10.1002/dc.25494

Yaogong Li, Yonca Kanber, Derin Caglar, Wassim Kassouf, Manon Auger, Fadi Brimo

{"title":"The Spectrum of Polyoma Virus and Polyoma Virus-Like Changes in Urine Cytology: When Should an Atypical Diagnosis Be Considered.","authors":"Yaogong Li, Yonca Kanber, Derin Caglar, Wassim Kassouf, Manon Auger, Fadi Brimo","doi":"10.1002/dc.25494","DOIUrl":"https://doi.org/10.1002/dc.25494","url":null,"abstract":"Background: While the Paris system for reporting urinary cytology states that cells with well-recognized and typical changes of polyoma virus (PV) infection should not lead to a diagnosis of 'atypia, the prognostic significance of PV-like features is unknown.Methods: Included were 284 urine cytology cases with PV or PV-like changes. Four cell types were identified. Cell A was typical of PV infection, cell B had a spider-web chromatin pattern, and cells C and D were degenerated cells with clumpy chromatin or homogeneous severely hyperchromatic nuclei, respectively. Events were correlated with a subsequent histological diagnosis of high-grade urothelial carcinoma (HGUC).Results: 47% of cases had more than one cell type. The most common cell was D (64%) and the least common was A (27%). The most common cell to be present in isolation was D (n = 109, 60%). 92% of cases with cell A had other cell types. Overall, the presence of cell A was associated with a benign follow-up (1.2% association with HGUC). There was a gradual increase in the association with a HGUC diagnosis in cases with cells B (PPV = 8%), C (PPV = 15.5%), and D (PPV = 44%). The presence of only cells B, C, or D was predictive of HGUC in 22.4%, 33.3%, and 61.5%, respectively.Conclusions: Cases with cell type A can be confidently diagnosed as 'negative for HGUC', even in the presence of associated cells with PV-like changes. Cases with cells displaying PV-like features (cell type B, C, or D) in the absence of type A features may represent degenerated HGUC cells.","PeriodicalId":11349,"journal":{"name":"Diagnostic Cytopathology","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2025-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144246943","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Retrospective Analysis of 1151 Chinese Women With Atypical Glandular Cells: Impact of High-Risk Human Papilloma Virus Status and Age on Cervical and Endometrial Neoplasia Risk. 1151例中国非典型腺细胞女性的回顾性分析：高危人乳头瘤病毒状态和年龄对宫颈和子宫内膜瘤风险的影响

IF 1 4区医学

Diagnostic Cytopathology Pub Date : 2025-06-09 DOI: 10.1002/dc.25495

Ruhang Fan, Shuang Song, Haiyan Shi, Xiaofei Zhang, Bingjian Lu

{"title":"A Retrospective Analysis of 1151 Chinese Women With Atypical Glandular Cells: Impact of High-Risk Human Papilloma Virus Status and Age on Cervical and Endometrial Neoplasia Risk.","authors":"Ruhang Fan, Shuang Song, Haiyan Shi, Xiaofei Zhang, Bingjian Lu","doi":"10.1002/dc.25495","DOIUrl":"https://doi.org/10.1002/dc.25495","url":null,"abstract":"Objective: To investigate the clinical significance of high-risk human papillomavirus (hrHPV) testing and age in women with atypical glandular cells (AGC) on Pap tests.Methods: We retrospectively analyzed the relationship between hrHPV and cytology co-testing, follow-up histopathology within 6 months, age, and other demographic features in a large cohort of AGC patients from a single Chinese academic institution.Results: Among1510 AGC patients, 1151, 1260, and 866 patients had histopathologic results, hrHPV co-testing, and both, respectively. High-grade squamous intraepithelial lesions (HSIL)/adenocarcinoma in situ (AIS) and worse lesions (HSIL/AIS+) and endometrial atypical hyperplasia (EAH)/endometrial carcinoma (EC) (EAH/EC+) were present in 27.8% (281/1009) and 25.1% (113/450) patients, respectively. hrHPV was positive in 34.5% (435/1260) patients. Among hrHPV+ patients with genotyping by the Aptima assay, 48.8% (125/256) had HPV16 and/or 18/45. Compared to hrHPV- patients, hrHPV+ women had a significantly increased risk of HSIL/AIS+ (OR: 10.958, 95% CI: 7.657-15.682), particularly with HPV16 and/or18/45 (OR: 3.556, 95% CI: 2.122-5.959; both p < 0.001). Among hrHPV- patients, those aged ≥ 40 years had higher risks of HSIL/AIS+ (including 18 HPV-independent and 11 metastatic adenocarcinomas; OR: 5.882, 95% CI: 2.702-12.806) and EAH/EC+ (OR: 7.622, 95% CI: 3.188-18.225) compared to younger patients (both p < 0.001).Conclusions: Combining hrHPV testing and age effectively stratifies risks in AGC patients: hrHPV positivity predicts high-grade cervical lesions, while older hrHPV-negative women are more likely to have endometrial or extra-uterine malignancies. These findings may optimize management of AGC patients with cumulative supportive data.","PeriodicalId":11349,"journal":{"name":"Diagnostic Cytopathology","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2025-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144246942","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Correlation of Cytology and Histology of Breast Phyllodes Tumor: Atypical Spindle Cells and Multinucleated Cells 乳腺叶状瘤细胞学与组织学的相关性：非典型梭形细胞和多核细胞。

IF 1 4区医学

Diagnostic Cytopathology Pub Date : 2025-06-05 DOI: 10.1002/dc.25492

Takahiko Sakuma, Mina Yamashita, Masanori Ando, Koji Matsuo

引用次数: 0