Correlation of Cytology and Histology of Breast Phyllodes Tumor: Atypical Spindle Cells and Multinucleated Cells.

IF 1 4区 医学 Q4 MEDICAL LABORATORY TECHNOLOGY
Takahiko Sakuma, Mina Yamashita, Masanori Ando, Koji Matsuo
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引用次数: 0

Abstract

A case of clinically malignant phyllodes tumor (PT) of the breast is reported. A 55-year-old woman with a lump in her left breast, which had been diagnosed as a fibroadenoma by fine needle aspiration (FNA) cytology five year before, noticed abruptly accelerated growth of the tumor. Repeated FNA cytology revealed atypical spindle and multinucleated cells, but the origin of these atypical cells could not be specifically determined. The rapid growth of the tumor resulted in an open skin ulcer and an emergent mastectomy was performed to control the intractable bleeding from the ulcer. The histological diagnosis was PT. The cytological and histological findings were compared, and there was favorable correlation. Although the tumour was clearly malignant clinically, it did not fulfill the WHO criteria for malignant PT completely. The desirable modification of the diagnostic criteria for malignant PT is discussed.

乳腺叶状瘤细胞学与组织学的相关性:非典型梭形细胞和多核细胞。
本文报告1例乳腺临床恶性叶状瘤(PT)。一名55岁女性左乳肿块,5年前通过细针穿刺细胞学检查诊断为纤维腺瘤,发现肿瘤突然加速生长。反复FNA细胞学检查显示非典型梭形细胞和多核细胞,但这些非典型细胞的来源无法明确确定。肿瘤的快速生长导致开放性皮肤溃疡,并进行紧急乳房切除术以控制溃疡的难治性出血。组织学诊断为PT,细胞学和组织学结果比较,两者有良好的相关性。虽然该肿瘤在临床上是明显的恶性肿瘤,但它不完全符合WHO的恶性PT标准。讨论了恶性PT诊断标准的理想修改。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Diagnostic Cytopathology
Diagnostic Cytopathology 医学-病理学
CiteScore
2.60
自引率
7.70%
发文量
163
审稿时长
3-6 weeks
期刊介绍: Diagnostic Cytopathology is intended to provide a forum for the exchange of information in the field of cytopathology, with special emphasis on the practical, clinical aspects of the discipline. The editors invite original scientific articles, as well as special review articles, feature articles, and letters to the editor, from laboratory professionals engaged in the practice of cytopathology. Manuscripts are accepted for publication on the basis of scientific merit, practical significance, and suitability for publication in a journal dedicated to this discipline. Original articles can be considered only with the understanding that they have never been published before and that they have not been submitted for simultaneous review to another publication.
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