{"title":"An Anus By Any Other Name….","authors":"Lester Gottesman","doi":"10.1097/DCR.0000000000003503","DOIUrl":"https://doi.org/10.1097/DCR.0000000000003503","url":null,"abstract":"","PeriodicalId":11299,"journal":{"name":"Diseases of the Colon & Rectum","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2024-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142806198","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"3-Dimensional Pouchography: A Video Tutorial.","authors":"Stefan D Holubar","doi":"10.1097/DCR.0000000000003505","DOIUrl":"https://doi.org/10.1097/DCR.0000000000003505","url":null,"abstract":"","PeriodicalId":11299,"journal":{"name":"Diseases of the Colon & Rectum","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2024-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142799770","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Robotic Low Anterior Resection With En Bloc Total Abdominal Hysterectomy With Bilateral Salpingo-oophorectomy.","authors":"Ankit Sharma, Yogesh Bansod, Avanish Saklani","doi":"10.1097/DCR.0000000000003396","DOIUrl":"https://doi.org/10.1097/DCR.0000000000003396","url":null,"abstract":"","PeriodicalId":11299,"journal":{"name":"Diseases of the Colon & Rectum","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2024-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142799773","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Increased Utilizing Magnetic Resonance Enterography in Crohn's Disease.","authors":"Muhammed Bahaddin Durak","doi":"10.1097/DCR.0000000000003610","DOIUrl":"https://doi.org/10.1097/DCR.0000000000003610","url":null,"abstract":"","PeriodicalId":11299,"journal":{"name":"Diseases of the Colon & Rectum","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2024-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142799771","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Fred C Kobylarz, Dwight D Eisenhower, Alice Lee, Pamela L Burgess
{"title":"Response to \"Specialization Reduces Cost Associated with Colon Cancer Care: A Cost Analysis\".","authors":"Fred C Kobylarz, Dwight D Eisenhower, Alice Lee, Pamela L Burgess","doi":"10.1097/DCR.0000000000003621","DOIUrl":"https://doi.org/10.1097/DCR.0000000000003621","url":null,"abstract":"","PeriodicalId":11299,"journal":{"name":"Diseases of the Colon & Rectum","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2024-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142799772","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Marco Bertucci Zoccali, Cintia Mayumi Sakurai Kimura, Brandon C Chapman, Tamzin Cuming, Carmen Fong, Naomi Jay, Jennifer Kaplan, Michelle J Khan, Craig A Messick, Vlad V Simianu, Jeremy J Sugrue, Luis F Barroso
{"title":"Management of Anal Dysplasia: A Pragmatic Summary of the Current Evidence and Definition of Clinical Practices for Prevention, Diagnosis, and Treatment.","authors":"Marco Bertucci Zoccali, Cintia Mayumi Sakurai Kimura, Brandon C Chapman, Tamzin Cuming, Carmen Fong, Naomi Jay, Jennifer Kaplan, Michelle J Khan, Craig A Messick, Vlad V Simianu, Jeremy J Sugrue, Luis F Barroso","doi":"10.1097/DCR.0000000000003444","DOIUrl":"https://doi.org/10.1097/DCR.0000000000003444","url":null,"abstract":"","PeriodicalId":11299,"journal":{"name":"Diseases of the Colon & Rectum","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2024-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142784477","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Effectiveness of Organ Preservation for Locally Advanced Rectal Cancer With Complete Clinical Response After Neoadjuvant Chemoradiotherapy: Bayesian Network Meta-analysis.","authors":"Kaibo Ouyang, Zifeng Yang, Yuesheng Yang, Zejian Lyu, Junjiang Wang, Yong Li","doi":"10.1097/DCR.0000000000003484","DOIUrl":"https://doi.org/10.1097/DCR.0000000000003484","url":null,"abstract":"<p><strong>Background: </strong>Neoadjuvant chemoradiotherapy followed by radical surgery is the common treatment for patients with locally advanced rectal cancer. Presently, for patients with complete clinical response after neoadjuvant chemoradiotherapy, organ preservation (\"watch-and-wait\" and local excision strategies) has been increasingly favored. However, the optimal treatment for patients with complete clinical response remains still unclear.</p><p><strong>Objective: </strong>This study aimed to use Bayesian meta-analysis to determine the best treatment for patients with locally advanced rectal cancer with complete clinical response among radical surgery, local excision, and watch and wait strategies.</p><p><strong>Data sources: </strong>PubMed, Web Of Science, Cochrane Library and Embase(Ovid) were searched until December 31, 2023.</p><p><strong>Study selection: </strong>Studies that compared two or more treatments for patients with complete clinical response were included.</p><p><strong>Intervention: </strong>The analysis was completed via Bayesian meta-analysis using random-effects model.</p><p><strong>Main outcomes: </strong>Surgery-related complications, local recurrence, distant metastasis, 5-year overall and disease-free survival rate.</p><p><strong>Result: </strong>Eleven articles met inclusion criteria. The groups of watch and wait and local excision exhibited a higher rate of tumor recurrence compared to radical surgery group (OR [95% CI]: watch and wait VS radical surgery: 9.10 [3.30, 32.3], local excision VS radical surgery: 2.93 [1.05, 9.95]). The distant metastasis, overall and disease-free survival rates of 3 treatments were not statistically different. The radical surgery group had the most number of stoma, and had the greatest risk of morbidity than the watch and wait group (OR[95%CI]: watch and wait VS radical surgery: 0.00 [0.00, 0.12]).</p><p><strong>Limitations: </strong>The study included only 1 randomized controlled trial compared to 10 observational studies, which could affect overall quality. Funnel plots of disease-free survival rates and stoma suggest significant publication bias among studies which compared radical surgery with watch and wait strategy.</p><p><strong>Conclusion: </strong>The watch and wait strategy could be optimal for patients with locally advanced rectal cancer with complete clinical response after neoadjuvant chemoradiotherapy.</p>","PeriodicalId":11299,"journal":{"name":"Diseases of the Colon & Rectum","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2024-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142784474","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Sexual Dysfunction After Pelvic Radiation.","authors":"Alexandra N Jones, Hillary L Simon","doi":"10.1097/DCR.0000000000003618","DOIUrl":"https://doi.org/10.1097/DCR.0000000000003618","url":null,"abstract":"","PeriodicalId":11299,"journal":{"name":"Diseases of the Colon & Rectum","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2024-12-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142767375","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Deciphering Early Onset Colorectal Cancer: Molecular Profiling of the Tumor Microenvironment.","authors":"Munir H Buhaya, Emina H Huang","doi":"10.1097/DCR.0000000000003447","DOIUrl":"https://doi.org/10.1097/DCR.0000000000003447","url":null,"abstract":"","PeriodicalId":11299,"journal":{"name":"Diseases of the Colon & Rectum","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2024-12-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142767194","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Eyal Aviran, Dan Assaf, Karen Zaghiyan, Phillip Fleshner
{"title":"Has the Use of Enhanced Recovery Protocols in Colorectal Surgery Increased Postoperative Bleeding Complications?","authors":"Eyal Aviran, Dan Assaf, Karen Zaghiyan, Phillip Fleshner","doi":"10.1097/DCR.0000000000003581","DOIUrl":"https://doi.org/10.1097/DCR.0000000000003581","url":null,"abstract":"<p><strong>Background: </strong>Enhanced recovery after surgery (ERAS) protocols are multimodal perioperative care pathways shown to improve postoperative complications and decrease length of stay after surgery. A critical component of an enhanced recovery after surgery protocol is the use of multimodal non-opiate analgesia using non-steroidal anti-inflammatory drugs and COX-2 inhibitors.</p><p><strong>Objective: </strong>To compare the incidence of postoperative gastrointestinal bleeding between patients treated with and without an enhanced recovery after surgery protocol.</p><p><strong>Design: </strong>Retrospective review of a prospective maintained colorectal registry.</p><p><strong>Settings: </strong>Large colorectal referral center.</p><p><strong>Patients: </strong>Preoperative elective colorectal surgery requiring an anastomosis.</p><p><strong>Intervention: </strong>Standardized enhanced recovery after surgery protocol included celecoxib and ketorolac.</p><p><strong>Main outcome: </strong>Postoperative outcomes included bleeding (+/- sequelae), reduction in hematocrit after operation, intervention for bleeding (transfusion, endoscopy or surgery), length of stay and hospital readmission.</p><p><strong>Results: </strong>The enhanced recovery after surgery group (n = 630) and non-enhanced recovery after surgery groups (n = 739) were comparable in baseline clinical features except for surgical indication, with more inflammatory bowel disease and less malignant disease in the enhanced recovery after surgery group. Minimally invasive surgery was more commonly performed in the enhanced recovery after surgery group. Both bleeding with sequelae (p < 0.0001) and bleeding without sequelae (p = 0.0004) were significantly more common in the enhanced recovery after surgery group compared to the non-enhanced recovery after surgery group. In addition, there was a significantly larger hematocrit decline after operation noted in the enhanced recovery after surgery group (p < 0.0001). Both the need for transfusion and intervention for bleeding however did not significantly differ between patient groups. Factors associated with bleeding were the use of an enhanced recovery after surgery protocol (OR = 2.96; 95% CI, 1.57-5.58; p < 0.001) and performing a small to large bowel anastomosis (OR= 2.68; 95% CI, 1.49-4.81; p < 0.001).</p><p><strong>Limitation: </strong>Retrospective observational design and inability to determine which component of the enhanced recovery after surgery protocol caused the bleeding.</p><p><strong>Conclusion: </strong>Use of an enhanced recovery after surgery protocol in patients undergoing colorectal surgery with an anastomosis is associated with an increased incidence of bleeding without significant difference in the need for transfusion or intervention. See Video Abstract.</p>","PeriodicalId":11299,"journal":{"name":"Diseases of the Colon & Rectum","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2024-12-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142767343","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}