Diseases of the Colon & Rectum最新文献

{"title":"Managing Reach Issues in Left Colectomy: Retroileal Tunnel With Arc of Riolan Preservation.","authors":"Lucas Faraco Sobrado, Carlos Walter Sobrado, Carlos Frederico Sparapan Marques, Ulysses Ribeiro-Junior","doi":"10.1097/DCR.0000000000003653","DOIUrl":"https://doi.org/10.1097/DCR.0000000000003653","url":null,"abstract":"","PeriodicalId":11299,"journal":{"name":"Diseases of the Colon & Rectum","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2025-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143986585","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Being a Writer.","authors":"James Church","doi":"10.1097/DCR.0000000000003795","DOIUrl":"https://doi.org/10.1097/DCR.0000000000003795","url":null,"abstract":"","PeriodicalId":11299,"journal":{"name":"Diseases of the Colon & Rectum","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2025-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143991676","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Legacy of Campaign_52: What the Future Holds for Female Pelvic Fistulas in Africa.","authors":"Wissam J Halabi, Chucheep Sahakitrungruang, Hillary Mirera Mabeya, Carolyne M Aluku, Khaled Kouteich, Afshin Iranpour, Maher A Abbas","doi":"10.1097/DCR.0000000000003801","DOIUrl":"https://doi.org/10.1097/DCR.0000000000003801","url":null,"abstract":"","PeriodicalId":11299,"journal":{"name":"Diseases of the Colon & Rectum","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2025-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143988320","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Impact of Preoperative Serum High Mobility Group Box-1 on Recurrence in Patients With Colorectal Cancer: A Prospective Observational Study.","authors":"Jun Watanabe, Hisanaga Horie, Kazuhiko Kotani, Kazuma Rifu, Mineyuki Tojo, Homare Ito, Yoshiyuki Inoue, Koji Koinuma, Hironori Yamaguchi, Naohiro Sata","doi":"10.1097/DCR.0000000000003814","DOIUrl":"https://doi.org/10.1097/DCR.0000000000003814","url":null,"abstract":"<p><strong>Background: </strong>High mobility group box 1 can serve as a marker for a follow-up of postoperative gastrointestinal cancer progression. However, we do not know the role of preoperative high mobility group box 1 measurement in an observation of longer-term recurrence of cancer and for colorectal cancer.</p><p><strong>Objective: </strong>This study aimed to evaluate the prediction of high mobility group box 1 on a long-term recurrence in patients with colorectal cancer.</p><p><strong>Design: </strong>This was a prospective cohort study.</p><p><strong>Patients: </strong>A cohort of 95 patients who underwent surgery for colorectal cancer between 2015 to 2018 were included.</p><p><strong>Main outcome measures: </strong>Serum high mobility group box 1 levels were measured preoperatively. Recurrence-free survival was evaluated using multivariable Cox regression analysis.</p><p><strong>Results: </strong>Serum mean high mobility group box 1 levels were 8.7 (standard deviation 8.0) ng/mL. The high-high mobility group box 1 group comprised 35 patients. The median recurrence-free survival duration was 5 years in both high- and low-high mobility group box 1 groups. The multivariable hazard ratios for high-high mobility group box 1 in relation to recurrence-free survival was 4.45 (95% confidence interval, 1.29-15.38, p = 0.02).</p><p><strong>Limitations: </strong>The sample size from a single site may limit generalizability of findings.</p><p><strong>Conclusion: </strong>Preoperative high-high mobility group box 1 levels were predictive of poorer recurrence-free survival in patients with colorectal cancer. Further studies are needed to confirm the use of high mobility group box 1 in clinical practice on recurrence-free survival. See Video.</p>","PeriodicalId":11299,"journal":{"name":"Diseases of the Colon & Rectum","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2025-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143958575","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Robotic Total Mesorectal Excision-Stepwise Narrative.","authors":"Rajesh S Shinde, Monika Pohekar, Murali V","doi":"10.1097/DCR.0000000000003572","DOIUrl":"https://doi.org/10.1097/DCR.0000000000003572","url":null,"abstract":"","PeriodicalId":11299,"journal":{"name":"Diseases of the Colon & Rectum","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2025-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144062721","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Stoma Rate and Oncological Outcomes of Primary TaTME Vs Completion TaTME in Patients With Early-Stage Rectal Cancer.","authors":"Annabel S van Lieshout, Laura R Moolenaar, Floor F A C Tobben, Stefan E van Oostendorp, Lisanne J H Smits, Jeroen C Hol, Eric H J Belgers, Eric J T H Belt, Steven J Oosterling, Colin Sietses, Pascal G Doornebosch, Roel Hompes, Jurriaan B Tuynman","doi":"10.1097/DCR.0000000000003794","DOIUrl":"https://doi.org/10.1097/DCR.0000000000003794","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Background: &lt;/strong&gt;Local excision as a first step in the treatment of early rectal cancer has gained interest. However, in the presence of histopathological risk factors, (inter)national guidelines recommend completion total mesorectal excision. Although oncologically safe, completion total mesorectal excision is associated with an increased end-colostomy rate compared to primary total mesorectal excision, especially in distal lesions. Transanal total mesorectal excision may facilitate lower anastomoses, potentially reducing end-colostomy rates.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Objective: &lt;/strong&gt;To compare the end-colostomy rate and oncological outcomes of primary transanal total mesorectal excision with local excision followed by completion transanal total mesorectal excision in patients with cT1-2N0M0 rectal cancer.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Design: &lt;/strong&gt;Data were prospectively collected from 6 Dutch high-volume centers experienced in transanal total mesorectal excision and retrospectively analyzed.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Patients: &lt;/strong&gt;All patients with cT1-2N0M0 rectal cancer who underwent primary transanal total mesorectal excision or local excision followed by completion transanal total mesorectal excision between 2012 and 2022.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Main outcome measures: &lt;/strong&gt;The primary outcome was end-colostomy rate. Secondary outcomes included anastomotic leakage, involvement of the circumferential resection margin, specimen quality, local recurrence, distant metastases, overall survival and disease-free survival.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;A total of 150 patients were included with a median follow-up of 32 and 23 months for primary transanal total mesorectal excision and local excision followed by completion transanal total mesorectal excision, respectively. The end-colostomy rate was significantly lower in the local excision followed by completion transanal total mesorectal excision group (21%) compared to the primary transanal total mesorectal excision group (42%, p = 0.022). More anastomotic leakages occurred in the local excision followed by completion transanal total mesorectal excision group (33% vs 18%, p = 0.064). No differences were observed in circumferential resection margin involvement and specimen quality. Two-year local recurrence rates were 4% for primary transanal total mesorectal excision and 3% for local excision followed by completion transanal total mesorectal excision (p = 0.343), while distant metastases occurred in 8% and 10% (p = 0.424), respectively. There were no significant differences in 2-year overall survival (88% vs 97%, p = 0.101) and 2-year disease free survival (82% vs 90%, p = 0.463) between groups.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Limitations: &lt;/strong&gt;The small sample size, which precluded correction for group differences, and selection bias.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusion: &lt;/strong&gt;This study demonstrated that local excision followed by completion transanal total mesorectal excision for cT1-2N0 rectal cancer did not increase the end-colo","PeriodicalId":11299,"journal":{"name":"Diseases of the Colon & Rectum","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2025-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143956870","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Outreach: A World of Possibilities.","authors":"Graham L Newstead","doi":"10.1097/DCR.0000000000003701","DOIUrl":"10.1097/DCR.0000000000003701","url":null,"abstract":"","PeriodicalId":11299,"journal":{"name":"Diseases of the Colon & Rectum","volume":" ","pages":"505-508"},"PeriodicalIF":3.2,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143398643","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Long-term Outcomes After Minimally Invasive Ventral Rectopexy for Rectal Prolapse Using Biological Graft Prosthesis: A 15-Year Retrospective Cohort Study.","authors":"Michael L R Lonne, Amy M Y Cao, Ashley Jenkin, Liam J Convie, Grant E Stevenson, Jayson M Moloney, Andrew R L Stevenson","doi":"10.1097/DCR.0000000000003661","DOIUrl":"10.1097/DCR.0000000000003661","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Background: &lt;/strong&gt;Minimally invasive ventral rectopexy has widely become the preferred prolapse procedure. However, there have been recent concerns regarding the safety of permanent synthetic mesh in the pelvis. Biological grafts have also been commonly used as an alternative prosthesis, but data on their safety and the longevity of the prolapse repair have been lacking.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Objective: &lt;/strong&gt;To assess the short- and long-term safety and efficacy of biological grafts in minimally invasive ventral rectopexy.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Design: &lt;/strong&gt;Retrospective cohort study using data from a prospectively collected database.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Settings: &lt;/strong&gt;Single surgeon at a single tertiary hospital in Australia.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Patients: &lt;/strong&gt;There were 366 patients with minimum 6-month follow-up undergoing minimally invasive ventral rectopexy using a biological graft between January 1, 2008, and October 5, 2023.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Main outcome measures: &lt;/strong&gt;Overall recurrence, complications, and functional outcomes.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;A total of 57 patients (15.6%) experienced a recurrence during the study period, with a median follow-up time of 35.5 months (range, 6-183 months). Of these, 17 (4.6%) were full-thickness recurrence. The Kaplan-Meier estimates of the overall 1-, 3-, and 5-year recurrence rates were 2.0%, 6.0%, and 16.0%, respectively. There was no statistically significant difference in recurrence for patients who presented with a full-thickness prolapse compared to those with other indications (16.8% vs 14.2%, p = 0.29). Overall, there were a total of 34 complications that occurred in 29 patients (7.9%). Nineteen patients (5.2%) required a return to theater. There was no reported graft-related complication or long-term pelvic pain. Ninety-eight percent of patients had symptomatic improvement and were satisfied with their outcome.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Limitations: &lt;/strong&gt;Retrospective study and generalizability of the results from single surgeon experience. Late recurrences may have been missed.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusions: &lt;/strong&gt;Minimally invasive ventral rectopexy using a biological graft is both safe and effective, offering acceptable short- and long-term recurrence rates and overall complications with no graft-related morbidity. See Video Abstract .&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Resultados a largo plazo despus de la rectopexia ventral mnimamente invasiva para el prolapso rectal utilizando prtesis de injerto biolgico un estudio de cohorte retrospectivo de aos: &lt;/strong&gt;ANTECEDENTES:La rectopexia ventral mínimamente invasiva se ha convertido en gran medida, como el procedimiento preferido para el prolapso. Sin embargo, recientemente ha habido inquietudes con respecto a la seguridad de la malla sintética permanente en la pelvis. Los injertos biológicos también se han utilizado comúnmente como prótesis alterna, pero faltan datos sobre su seguridad y la longevidad de la reparación del prolapso.OBJETIVO:Evaluar la segur","PeriodicalId":11299,"journal":{"name":"Diseases of the Colon & Rectum","volume":" ","pages":"608-615"},"PeriodicalIF":3.2,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143064164","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Management of Obstetric Anal Sphincter Injuries.","authors":"Chloe Price, Ryan Cohen","doi":"10.1097/DCR.0000000000003697","DOIUrl":"10.1097/DCR.0000000000003697","url":null,"abstract":"","PeriodicalId":11299,"journal":{"name":"Diseases of the Colon & Rectum","volume":" ","pages":"510-513"},"PeriodicalIF":3.2,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143363805","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Outcome After Surgical Treatment for Chronic Pilonidal Sinus Disease: A Systematic Review of Common Surgical Techniques.","authors":"Ida-Marie Myron Wiinblad, Johan Ulrichsen, Birgitte Brandstrup","doi":"10.1097/DCR.0000000000003688","DOIUrl":"10.1097/DCR.0000000000003688","url":null,"abstract":"<p><strong>Background: </strong>The choice of operation for chronic pilonidal sinus disease remains controversial.</p><p><strong>Objective: </strong>To compare the outcomes of common operations for chronic pilonidal disease.</p><p><strong>Data sources: </strong>We searched PubMed, Embase, and the Cochrane Library.</p><p><strong>Study selection: </strong>We included randomized trials in English or Danish language, published 2002 to 2024 that compared outcomes of operations to treat chronic pilonidal disease in adults and teenagers.</p><p><strong>Interventions: </strong>We compared the outcomes of secondary healing, primary midline closure, Bascom, Limberg, and Karydakis flap operations.</p><p><strong>Main outcome measures: </strong>The primary outcome was recurrence; secondary outcomes were infection, healing time, and length of stay. We compared recurrence and infection rates in meta-analyses for all techniques. We assessed the risk of bias and the quality of all trials.</p><p><strong>Results: </strong>Fifty trials included a total of 5762 participants. In a meta-analysis, the flap operations had fewer recurrences than primary midline closure (OR 0.31; 95% CI, 0.19-0.51; p < 0.01). The trials comparing flap operations with secondary healing were heterogeneous and did not reach significance (OR 0.38; 95% CI, 0.13-1.13; p = 0.08). Recurrence was similar between Limberg and Karydakis operations. Infection rates were lower for the flap operations compared with primary closure (OR 0.33; 95% CI, 0.23-0.48; p < 0.01) and with secondary healing (OR 0.48; 95% CI, 0.30-0.77; p < 0.01). Two trials tested Bascom procedure against Limberg operation without significant differences. All trials found secondary healing to have significantly longer healing times than any other operation.</p><p><strong>Limitations: </strong>Most studies had a high or medium risk of bias, resulting in very low to low certainty of evidence. The trials generally had small numbers, short follow-ups, and no reported primary outcomes or power calculations.</p><p><strong>Conclusions: </strong>Primary closure and secondary healing performed poorly compared with the flap techniques. Most trials tested Limberg operation; only 2 tested Bascom operation. The literature suggests the surgeon's expertise determines the choice of flap technique.</p>","PeriodicalId":11299,"journal":{"name":"Diseases of the Colon & Rectum","volume":" ","pages":"515-529"},"PeriodicalIF":3.2,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143472308","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}