Diseases of the Colon & Rectum最新文献

{"title":"Reframing the Microbiome's Role in Anastomotic Leak: From Composition to Causality.","authors":"Alpaslan Sahin","doi":"10.1097/DCR.0000000000003923","DOIUrl":"10.1097/DCR.0000000000003923","url":null,"abstract":"","PeriodicalId":11299,"journal":{"name":"Diseases of the Colon & Rectum","volume":" ","pages":"e1895"},"PeriodicalIF":3.7,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144728737","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of Anal Cancer Screening Practices Among a National Cohort of Veterans With HIV.","authors":"Austin J Hewitt, Matthew J Freeman, Dana M Hayden, Evie H Carchman, Marin L Schweizer, Cristina B Sanger","doi":"10.1097/DCR.0000000000003928","DOIUrl":"10.1097/DCR.0000000000003928","url":null,"abstract":"<p><strong>Background: </strong>When available, anal cytology is used for initial anal cancer screening, whereas diagnostic histology is typically performed after abnormal cytology or in symptomatic individuals.</p><p><strong>Objective: </strong>Analyze index anal evaluations (cytology vs histology) in veterans with HIV.</p><p><strong>Design: </strong>Retrospective cohort study.</p><p><strong>Settings: </strong>One hundred thirty Department of Veterans Affairs medical centers.</p><p><strong>Patients: </strong>Veterans with HIV who received care from 1999 to 2023.</p><p><strong>Main outcome measures: </strong>Distribution of index anal evaluations as cytology or histology, annual incidence rates of index evaluations, and regional anal cancer prevalence and screening rates.</p><p><strong>Results: </strong>Among 48,368 veterans with HIV, 7127 (15%) had at least 1 anal evaluation. Index evaluations were cytology in 4477 (63%) and histology in 2650 (37%). The mean annual rate of index anal evaluations was 1.04%, with a relative decrease in 2020 and beyond. Among patients with anal evaluations, the Pacific region had the highest proportion of index cytology (77%), comprising 77% of evaluations, and the Continental region had the lowest (37%, p < 0.001). Conversely, the lowest and highest rates of anal cancer were observed in the Pacific and Continental regions, respectively (4.7% vs 9.4%, p < 0.001). However, this trend did not translate into differences in anal cancer rates between the 2 regions when comparing all veterans with HIV (1.01% vs 0.90%, p = 0.52).</p><p><strong>Limitations: </strong>Retrospective data.</p><p><strong>Conclusions: </strong>In this national analysis of veterans with HIV, only 15% had an anal evaluation, despite recommendations for annual screening. The majority of index evaluations were screening assessments with cytology (63%). There was a relative decrease in index evaluations after 2020. Regional screening differences were observed among patients with anal evaluations. Higher anal cancer detection was seen in the region with the lowest screening and lower detection in the region with the highest screening. Interestingly, this correlation did not persist when examining the overall regional populations of veterans with HIV, including those never evaluated. See Video Abstract.</p><p><strong>Evaluacin de las prcticas de deteccin del cncer anal en una cohorte nacional de veteranos con vih: </strong>ANTECEDENTES:Cuando está disponible, la citología anal se utiliza para el cribado inicial del cáncer anal, mientras que la histología diagnóstica se suele realizar tras una citología anómala o en personas sintomáticas.OBJETIVO:Analizar las evaluaciones anales índice (citología frente a histología) en veteranos con VIH.DISEÑO:Estudio de cohorte retrospectivo.ENTORNO:Ciento treinta centros médicos del Departamento de Asuntos de Veteranos.PACIENTES:Veteranos con VIH que recibieron atención entre 1999 y 2023.PRINCIPALES RESULTADOS Y MEDI","PeriodicalId":11299,"journal":{"name":"Diseases of the Colon & Rectum","volume":" ","pages":"1276-1284"},"PeriodicalIF":3.7,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144788482","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Maroon DCR Website Banner: A Cache of Valuable Content-Part II.","authors":"Susan Galandiuk","doi":"10.1097/DCR.0000000000003945","DOIUrl":"https://doi.org/10.1097/DCR.0000000000003945","url":null,"abstract":"","PeriodicalId":11299,"journal":{"name":"Diseases of the Colon & Rectum","volume":"68 11","pages":"1231-1235"},"PeriodicalIF":3.7,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145354148","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pouch Inlet Transposition: A Novel Approach for Recurrent Small-Bowel Volvulus From Pouch Inlet Twists.","authors":"Stefan D Holubar, Olga Lavryk, Imran Khan, George Kereselidze, Michael Goldenshluger, Gilad Alon","doi":"10.1097/DCR.0000000000003724","DOIUrl":"10.1097/DCR.0000000000003724","url":null,"abstract":"","PeriodicalId":11299,"journal":{"name":"Diseases of the Colon & Rectum","volume":" ","pages":"e1882-e1883"},"PeriodicalIF":3.7,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144697859","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"V-Y Advancement Flap for Correcting Severe Perianal Fistulizing Crohn's Disease.","authors":"María A Casas, Nicholas S Murdoch Duncan, Agustin C Valinoti, Maximiliano E Bun, Nicolás A Rotholtz","doi":"10.1097/DCR.0000000000003828","DOIUrl":"10.1097/DCR.0000000000003828","url":null,"abstract":"","PeriodicalId":11299,"journal":{"name":"Diseases of the Colon & Rectum","volume":" ","pages":"e1884"},"PeriodicalIF":3.7,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144697860","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Autonomic Nerve Preserving Robotic Rectal Cancer Surgery: \"Radicality With Functionality\".","authors":"Somashkehar Sampige Prasanna, Kushal Agrawal, Ashwin Kyatsandra Rajagopal","doi":"10.1097/DCR.0000000000003749","DOIUrl":"10.1097/DCR.0000000000003749","url":null,"abstract":"","PeriodicalId":11299,"journal":{"name":"Diseases of the Colon & Rectum","volume":" ","pages":"e1890-e1893"},"PeriodicalIF":3.7,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144607807","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Management of Colorectal Peritoneal Metastases.","authors":"Lauren Weaver, Paolo Goffredo","doi":"10.1097/DCR.0000000000003943","DOIUrl":"10.1097/DCR.0000000000003943","url":null,"abstract":"","PeriodicalId":11299,"journal":{"name":"Diseases of the Colon & Rectum","volume":" ","pages":"1259-1262"},"PeriodicalIF":3.7,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144854844","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Time to Reconsider the Mechanism of Hemorrhoidectomy Pain.","authors":"Mina Sarofim","doi":"10.1097/DCR.0000000000003931","DOIUrl":"10.1097/DCR.0000000000003931","url":null,"abstract":"","PeriodicalId":11299,"journal":{"name":"Diseases of the Colon & Rectum","volume":" ","pages":"e1896"},"PeriodicalIF":3.7,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144793714","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Incidence and Risk Factors of Pulmonary Metastasis as the Initial Site of Metastasis After Surgical Resection for Rectal Cancer by TNM Stage.","authors":"Misol Do, Seijong Kim, Woo Yong Lee, Seong Hyeon Yun, Hee Cheol Kim, Yong Beom Cho, Jung Wook Huh, Yoon Ah Park, Jung Kyong Shin","doi":"10.1097/DCR.0000000000003899","DOIUrl":"10.1097/DCR.0000000000003899","url":null,"abstract":"<p><strong>Background: </strong>There are scant data on the incidence and risk factors associated with pulmonary metastasis in rectal cancer, particularly according to TNM stage.</p><p><strong>Objective: </strong>To determine the incidence of pulmonary metastasis in patients with stage I to III rectal cancer after surgical resection and to identify stage-specific risk factors.</p><p><strong>Design: </strong>A retrospective analysis was conducted of patients with rectal cancer who underwent radical resection.</p><p><strong>Settings: </strong>Samsung Medical Center from January 2007 to December 2019.</p><p><strong>Patients: </strong>A total of 3504 patients were diagnosed as having either a pathologic complete response after neoadjuvant concurrent chemoradiotherapy and subsequent radical resection or stage I to III rectal cancer with no initial metastasis.</p><p><strong>Main outcome measures: </strong>The main outcomes were the incidence of pulmonary metastasis and overall survival.</p><p><strong>Results: </strong>Of the patients, 313 (8.9%) developed pulmonary metastasis. The median time to pulmonary metastasis was 16 months (range, 6-92 months). The incidence rates of pulmonary metastasis by TNM stage were 2.0% (pathologic complete response), 2.4% (stage I), 8.0% (stage II), and 17.4% (stage III). For the neoadjuvant chemoradiotherapy group, the incidence rates were 2.0% (pathologic complete response), 5.1% (stage I), 9.9% (stage II), and 21.4% (stage III). In the no neoadjuvant chemoradiotherapy group, the incidence rates were 1.0% (stage I), 6.5% (stage II), and 15.8% (stage III). Major risk factors for pulmonary metastasis included neoadjuvant chemoradiotherapy status, elevated CEA of ≥5 ng/mL, tumor location, (yp)TNM stage, (yp)T stage, vascular invasion, perineural invasion, and tumor budding.</p><p><strong>Limitations: </strong>Single-center retrospective study.</p><p><strong>Conclusions: </strong>As TNM stage increases, the incidence of pulmonary metastasis also increases, regardless of neoadjuvant chemoradiotherapy. Elevations in CEA levels, neoadjuvant chemoradiotherapy status, tumor location, vascular invasion, perineural invasion, and tumor budding were identified as risk factors for pulmonary metastasis in rectal cancer. Patients with these risk factors may benefit from protocolized surveillance to facilitate timely detection and management. See Video Abstract .</p><p><strong>Incidencia y factores de riesgo de la metstasis pulmonar como sitio inicial de metstasis tras la reseccin quirrgica del cncer rectal segn la clasificacin tnm: </strong>ANTECEDENTES:Existen pocos datos sobre la incidencia y los factores de riesgo asociados a la metástasis pulmonar en el cáncer rectal, especialmente según el estadio TNM.OBJETIVO:Determinar la incidencia de la metástasis pulmonar en pacientes con cáncer rectal en estadio I-III tras la resección quirúrgica e identificar los factores de riesgo específicos de cada estadio.DISEÑO:Se realizó un análisis ","PeriodicalId":11299,"journal":{"name":"Diseases of the Colon & Rectum","volume":" ","pages":"1285-1295"},"PeriodicalIF":3.7,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144728736","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reply.","authors":"Brian N Williams, Sang W Lee","doi":"10.1097/DCR.0000000000003925","DOIUrl":"10.1097/DCR.0000000000003925","url":null,"abstract":"","PeriodicalId":11299,"journal":{"name":"Diseases of the Colon & Rectum","volume":" ","pages":"e1897"},"PeriodicalIF":3.7,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144728733","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}