{"title":"Robotic Transperineal Lateral Lymph Node Dissection for Rectal Cancer Through a Single-Port System: the World's First Clinical Experience.","authors":"Atsushi Ogura, Yuki Murata, Norifumi Hattori, Yusuke Sato, Shinichi Umeda, Chie Tanaka, Tomoki Ebata, Mitsuro Kanda","doi":"10.1097/DCR.0000000000004356","DOIUrl":"https://doi.org/10.1097/DCR.0000000000004356","url":null,"abstract":"","PeriodicalId":11299,"journal":{"name":"Diseases of the Colon & Rectum","volume":" ","pages":""},"PeriodicalIF":3.1,"publicationDate":"2026-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148886727","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Selected Abstracts.","authors":"","doi":"10.1097/DCR.0000000000004464","DOIUrl":"https://doi.org/10.1097/DCR.0000000000004464","url":null,"abstract":"","PeriodicalId":11299,"journal":{"name":"Diseases of the Colon & Rectum","volume":" ","pages":""},"PeriodicalIF":3.1,"publicationDate":"2026-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148886760","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ankit Sarin, Christopher M Seffren, Hussam A Shwaib, Monique Couto Matos, Samuel Eisenstein, Marco Ferrara, Nell Maloney Patel, Sean J Langenfeld
{"title":"Artificial Intelligence for Colorectal Surgeons-Part I: Foundations and Clinical and Educational Applications.","authors":"Ankit Sarin, Christopher M Seffren, Hussam A Shwaib, Monique Couto Matos, Samuel Eisenstein, Marco Ferrara, Nell Maloney Patel, Sean J Langenfeld","doi":"10.1097/DCR.0000000000004138","DOIUrl":"10.1097/DCR.0000000000004138","url":null,"abstract":"<p><strong>Background: </strong>Artificial intelligence is rapidly transforming colorectal surgery through applications spanning screening to postoperative care. This 2-part review provides a comprehensive framework for understanding and implementing artificial intelligence technologies in surgical practice.</p><p><strong>Objective: </strong>Part I analyzes fundamental artificial intelligence concepts, clinical applications across the surgical continuum, and educational considerations for colorectal surgeons.</p><p><strong>Methods: </strong>Comprehensive literature review focusing on artificial intelligence applications in colorectal surgery, evaluating current evidence for clinical implementation and training approaches.</p><p><strong>Results: </strong>Artificial intelligence demonstrates measurable clinical impact across multiple domains. In screening, artificial intelligence-enhanced colonoscopy increases adenoma detection rates from 40.4% to 54.8% ( p < 0.001) in multicenter trials, with cross-validation on colonoscopy images demonstrating 96.4% polyp detection accuracy. Diagnostic applications include microsatellite instability prediction from histology and automated MRI tumor segmentation. Preoperatively, machine learning models predict mortality and morbidity, outperforming traditional risk measures such as the American Society of Anesthesiologists classification and the American College of Surgeon-National Surgical Quality Improvement Program. Intraoperatively, artificial intelligence has demonstrated early feasibility for real-time tissue plane, artificial intelligence-based automated perfusion assessment can predict anastomotic viability, and artificial intelligence can enable identification of critical structures such as pelvic nerves. Postoperatively, artificial intelligence is starting to detect complications hours before clinical diagnosis, reducing documentation time. Educational applications include artificial intelligence-enhanced simulation platforms, objective video-based performance assessment, and integration with virtual/augmented reality for immersive training experiences.</p><p><strong>Conclusions: </strong>Artificial intelligence technologies have achieved clinical validation for specific colorectal surgery applications, with several technologies receiving regulatory approval. Successful integration requires understanding fundamental concepts, appropriate clinical application, and structured training approaches. Part II of this series analyzes research applications, implementation resources, challenges, and future directions that will further transform surgical practice.</p>","PeriodicalId":11299,"journal":{"name":"Diseases of the Colon & Rectum","volume":" ","pages":"2230-2240"},"PeriodicalIF":3.1,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147527764","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Fabio Lopes de Queiroz, Marina Barbabela Grisolia de Oliveira, Daniel Mauricio Londoño Estrada
{"title":"Robotic Lateral-to-Medial Left Colon Dissection: A Technical Approach for Total Mesorectal Excision.","authors":"Fabio Lopes de Queiroz, Marina Barbabela Grisolia de Oliveira, Daniel Mauricio Londoño Estrada","doi":"10.1097/DCR.0000000000004247","DOIUrl":"10.1097/DCR.0000000000004247","url":null,"abstract":"","PeriodicalId":11299,"journal":{"name":"Diseases of the Colon & Rectum","volume":" ","pages":"2340-2342"},"PeriodicalIF":3.1,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148257572","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Maedeh Marzoughi, Evan Monge, Sarah Bradley, Mark P MacEachern, C Ann Vitous, Andrew J Read, Pasithorn A Suwanabol
{"title":"Delays in Diagnosis of Early-Onset Colorectal Cancer Across the United States: A Systematic Review.","authors":"Maedeh Marzoughi, Evan Monge, Sarah Bradley, Mark P MacEachern, C Ann Vitous, Andrew J Read, Pasithorn A Suwanabol","doi":"10.1097/DCR.0000000000004462","DOIUrl":"https://doi.org/10.1097/DCR.0000000000004462","url":null,"abstract":"<p><strong>Background: </strong>Early-onset colorectal cancer is now the leading cause of cancer death among adults under 50, with delays in diagnosis cited as a potential contributor to patients being diagnosed more frequently at advanced stages than their older counterparts. Despite this, few studies have comprehensively evaluated factors associated with diagnostic delays among patients with early-onset colorectal cancer in the United States.</p><p><strong>Objective: </strong>To synthesize factors contributing to early-onset colorectal cancer diagnostic delays in the United States using the Model of Pathways to Treatment to guide interventions that reduce diagnostic delays.</p><p><strong>Data sources: </strong>Two electronic databases were queried: Embase and MEDLINE.</p><p><strong>Study selection: </strong>Both qualitative and quantitative studies were included if they had early-onset colorectal cancer participants and a discussion of factors contributing to delays in diagnosis. Studies conducted outside of the United States, not peer-reviewed, and lacking primary data were excluded.</p><p><strong>Main outcome measures: </strong>Patient, provider, and system-level factors contributing to delays in diagnosis across the appraisal, help-seeking, and diagnostic intervals.</p><p><strong>Results: </strong>Among 35 included studies, only 8 utilized qualitative methods. Most studies examined broader trends in early-onset colorectal cancer instead of evaluating a specific interval, using stage at diagnosis as a proxy for delays. Additionally, many factors affected multiple intervals, highlighting that factors are crosscutting.</p><p><strong>Limitations: </strong>Findings may not be generalizable outside the United States, given differences in healthcare financing, access, and screening practices. Using late-stage diagnosis as a proxy for delays is also debated and could confound stage-based inferences about delay. Few studies capture the subjective experiences of younger patients or the clinical reasoning and constraints providers face when evaluating symptoms.</p><p><strong>Conclusions: </strong>Diagnostic delays in early-onset colorectal cancer are difficult to confine to a single interval and require system-level interventions to support earlier detection. More qualitative inquiry is necessary to identify effective interventions, including interviews that elicit patient and provider experiences of barriers.</p>","PeriodicalId":11299,"journal":{"name":"Diseases of the Colon & Rectum","volume":" ","pages":""},"PeriodicalIF":3.1,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148879633","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Artificial Intelligence-Assisted Anatomical Recognition System-Guided Robotic Total Mesorectal Excision and Autonomic Nerve Preservation for Rectal Neuroendocrine Tumor.","authors":"Yudai Fukui, Sung Uk Bae","doi":"10.1097/DCR.0000000000004183","DOIUrl":"10.1097/DCR.0000000000004183","url":null,"abstract":"","PeriodicalId":11299,"journal":{"name":"Diseases of the Colon & Rectum","volume":" ","pages":"2338"},"PeriodicalIF":3.1,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147282787","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Considerations on Upfront Surgery for Stage II/III Rectal Cancer.","authors":"Kun Xu, Haode Shen, Weidong Tong, Fan Li","doi":"10.1097/DCR.0000000000004314","DOIUrl":"10.1097/DCR.0000000000004314","url":null,"abstract":"","PeriodicalId":11299,"journal":{"name":"Diseases of the Colon & Rectum","volume":" ","pages":"2355"},"PeriodicalIF":3.1,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148149086","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Expert Commentary on Managing Reach in Colectomy: Achieving a Tension-Free Anastomosis.","authors":"H David Vargas","doi":"10.1097/DCR.0000000000004318","DOIUrl":"10.1097/DCR.0000000000004318","url":null,"abstract":"","PeriodicalId":11299,"journal":{"name":"Diseases of the Colon & Rectum","volume":" ","pages":"2252-2253"},"PeriodicalIF":3.1,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148162143","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Garrett Johnson, Tae L Hart, Mantaj S Brar, Selina Schmocker, Amandeep Pooni, Jordyn Vernon, Erin Kennedy
{"title":"Sexual Distress Is Common in Long-term Follow-up After Pelvic Pouch for Ulcerative Colitis: A Cross-Sectional Study.","authors":"Garrett Johnson, Tae L Hart, Mantaj S Brar, Selina Schmocker, Amandeep Pooni, Jordyn Vernon, Erin Kennedy","doi":"10.1097/DCR.0000000000004352","DOIUrl":"10.1097/DCR.0000000000004352","url":null,"abstract":"<p><strong>Background: </strong>Sexual dysfunction is common after pelvic pouch surgery for ulcerative colitis. Despite this, little work has been done to explore the degree of sexual distress this causes in patients.</p><p><strong>Objective: </strong>To determine the proportion of patients with ulcerative colitis who experience sexual distress after pelvic pouch surgery and to explore the effects of social demographics, age, bowel function, anxiety, and depression on sexual distress.</p><p><strong>Design: </strong>A cross-sectional survey that was emailed to patients.</p><p><strong>Settings: </strong>A large tertiary care teaching hospital.</p><p><strong>Patients: </strong>Patients who underwent pelvic pouch surgery for ulcerative colitis from 1980 to 2022.</p><p><strong>Interventions: </strong>Validated questionnaires included the 13-item Sexual Distress Scale, Hospital Anxiety and Depression Scale, and Colorectal Functional Outcome questionnaire.</p><p><strong>Main outcome measures: </strong>The primary outcome was the proportion of patients meeting established thresholds for sexual distress. Multivariable regression was used to evaluate associations between sexual distress and operative factors, age, sex, income, education, ethnicity, sexual orientation, and relationship status.</p><p><strong>Results: </strong>Of 1830 eligible patients, 497 responded and were included in the analysis. Overall, 194 patients (39%) screened positive for sexual distress. Women were disproportionately affected, with more than half reporting clinically significant distress (141/243; 57.8%). Female gender was the only independent preoperative predictor of sexual distress on multivariable analysis (OR 4.796; 95% CI, 3.119-7.374; p < 0.001). Poor bowel function, anxiety, and depression were all significantly more prevalent among patients with sexual distress (all p < 0.001).</p><p><strong>Limitations: </strong>Cross-sectional design limits causal inference. Selection and response bias are possible.</p><p><strong>Conclusions: </strong>Sexual distress is common after pelvic pouch surgery for ulcerative colitis, particularly among women, and is strongly associated with bowel dysfunction, anxiety, and depression. These findings highlight the importance of holistic preoperative and postoperative counseling and the consideration of psychological screening in follow-up care. Further research is needed to elucidate underlying mechanisms and develop targeted interventions. See Video Abstract.</p><p><strong>La disfuncin sexual es frecuente en el seguimiento a largo plazo tras la creacin de una bolsa plvica para la colitis ulcerosa un estudio transversal: </strong>ANTECEDENTES:La disfunción sexual es frecuente tras la cirugía de reservorio pélvico para la colitis ulcerosa. A pesar de ello, se ha investigado poco sobre el grado de malestar sexual que esto provoca en los pacientes.OBJETIVO:Determinar la proporción de pacientes con colitis ulcerosa que experimentan malestar sexual ","PeriodicalId":11299,"journal":{"name":"Diseases of the Colon & Rectum","volume":" ","pages":"2273-2282"},"PeriodicalIF":3.1,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148276567","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}